EC 1.1.1.176: 12alpha-hydroxysteroid dehydrogenase
OxidoreductasesOpen in Browse
CatLog read 12 records for EC 1.1.1.176 from 1 paper, for 3 organisms. Names in these papers: 12α-hydroxysteroid dehydrogenase (rCHIR), 12α-hydroxysteroid dehydrogenase (rCHYL), 12α-hydroxysteroid dehydrogenase (rCSCI).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 19 records for EC 1.1.1.176 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.176 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Metabolism of Oxo-Bile Acids and Characterization of Recombinant 12α-Hydroxysteroid Dehydrogenases from Bile Acid 7α-Dehydroxylating Human Gut Bacteria | Clostridium hiranonis, Clostridium hylemonae and 1 more | 12 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 12α-hydroxysteroid dehydrogenase (rCHIR) | Clostridium hiranonis | 12-Oxolithocholic acid | 72.09 | 0.03429 | 2.1 × 10³ | pH 7 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCHIR), 12-Oxolithocholic acid |
| 12α-hydroxysteroid dehydrogenase (rCHIR) | Clostridium hiranonis | Deoxycholic acid | 130.6 | 0.1754 | 740 | pH 7 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCHIR), Deoxycholic acid |
| 12α-hydroxysteroid dehydrogenase (rCHIR) | Clostridium hiranonis | NADP+ | 129.8 | 0.1279 | 1.01 × 10³ | pH 7 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCHIR), NADP+ |
| 12α-hydroxysteroid dehydrogenase (rCHIR) | Clostridium hiranonis | NADPH | 76.24 | 0.04037 | 1.89 × 10³ | pH 7 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCHIR), NADPH |
| 12α-hydroxysteroid dehydrogenase (rCHYL) | Clostridium hylemonae | 12-Oxolithocholic acid | 45.09 | 0.0327 | 1.38 × 10³ | pH 7 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCHYL), 12-Oxolithocholic acid |
| 12α-hydroxysteroid dehydrogenase (rCHYL) | Clostridium hylemonae | Deoxycholic acid | 72.52 | 0.1478 | 490 | pH 8 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCHYL), Deoxycholic acid |
| 12α-hydroxysteroid dehydrogenase (rCHYL) | Clostridium hylemonae | NADP+ | 66.72 | 0.1105 | 600 | pH 8 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCHYL), NADP+ |
| 12α-hydroxysteroid dehydrogenase (rCHYL) | Clostridium hylemonae | NADPH | 44.52 | 0.04831 | 920 | pH 7 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCHYL), NADPH |
| 12α-hydroxysteroid dehydrogenase (rCSCI) | Clostridium scindens | 12-Oxolithocholic acid | 31.13 | 0.01752 | 1.77 × 10³ | pH 7 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCSCI), 12-Oxolithocholic acid |
| 12α-hydroxysteroid dehydrogenase (rCSCI) | Clostridium scindens | Deoxycholic acid | 90.93 | 0.1786 | 510 | pH 7.5 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCSCI), Deoxycholic acid |
| 12α-hydroxysteroid dehydrogenase (rCSCI) | Clostridium scindens | NADP+ | 90.74 | 0.07988 | 1.14 × 10³ | pH 7.5 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCSCI), NADP+ |
| 12α-hydroxysteroid dehydrogenase (rCSCI) | Clostridium scindens | NADPH | 26.71 | 0.03401 | 790 | pH 7 | PMID 29549099 | Open record: 12α-hydroxysteroid dehydrogenase (rCSCI), NADPH |