Papers CatLog read

The 6,212 papers with a PubMed ID whose kcat, Km and kcat/Km values CatLog read from the paper, by title.

• "Catch 222," the effects of symmetry on ligand binding and catalysis in R67 dihydrofolate reductase as determined by mutations at Tyr-69 · PMID 15333637 · 14 records
• "Pinching" the ammonia tunnel of CTP synthase unveils coordinated catalytic and allosteric-dependent control of ammonia passage · PMID 30251661 · 31 records
• 'Super-perfect' enzymes: Structural stabilities and activities of recombinant triose phosphate isomerases from Pyrococcus furiosus and Thermococcus onnurineus produced in Escherichia coli · PMID 25824038 · 4 records
• (R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in… · PMID 14675446 · 20 records
• (S)-Mandelate dehydrogenase from Pseudomonas putida: mechanistic studies with alternate substrates and pH and kinetic isotope effects · PMID 10231535 · 20 records
• 1,2-β-Oligoglucan phosphorylase from Listeria innocua · PMID 24647662 · 10 records
• 1,6-α-L-Fucosidases from Bifidobacterium longum subsp. infantis ATCC 15697 Involved in the Degradation of Core-fucosylated N -Glycan · PMID 34429696 · 4 records
• 1-Aminocyclopropane-1-carboxylic acid oxidase reaction mechanism and putative post-translational activities of the ACCO protein · PMID 24244837 · 35 records
• 1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan · PMID 20399882 · 12 records
• 1.55Å-resolution structure of ent-copalyl diphosphate synthase and exploration of general acid function by site-directed mutagenesis · PMID 24036329 · 8 records
• 11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress · PMID 9405715 · 9 records
• 11β-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo · PMID 23415904 · 7 records
• 15-Hydroxyeicosatetraenoic acid dehydrogenase activity in microsomal fraction of mouse liver homogenate · PMID 3052453 · 2 records
• 2-Keto-4-hydroxyglutarate aldolase: purification and characterization of the homogeneous enzyme from bovine kidney · PMID 1587831 · 4 records
• 2-Ketogluconate Kinase from Cupriavidus necator H16: Purification, Characterization, and Exploration of Its Substrate Specificity · PMID 31261738 · 5 records
• 2-O-α-D-glucosylglycerol phosphorylase from Bacillus selenitireducens MLS10 possessing hydrolytic activity on β-D-glucose 1-phosphate · PMID 24466148 · 8 records
• 24-hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver x receptor… · PMID 19589875 · 7 records
• 3'-NADP and 3'-NAADP, Two Metabolites Formed by the Bacterial Type III Effector AvrRxo1 · PMID 27621317 · 4 records
• 3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282… · PMID 32087198 · 11 records
• 3-Hydroxy-3-methylglutaryl-coenzyme A reductase of Haloferax volcanii: role of histidine 398 and attenuation of activity by introduction of negative charge at position 404 · PMID 9007988 · 17 records
• 3-Hydroxyisobutyrate Dehydrogenase Is Involved in Both, Valine and Isoleucine Degradation in Arabidopsis thaliana · PMID 28705827 · 2 records
• 3-hydroxypropionyl-coenzyme A dehydratase and acryloyl-coenzyme A reductase, enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in the Sulfolobales · PMID 19429610 · 5 records
• 3-Hydroxypropionyl-coenzyme A synthetase from Metallosphaera sedula, an enzyme involved in autotrophic CO2 fixation · PMID 18165310 · 8 records
• 3-Isopropylmalate dehydrogenase from chemolithoautotroph Thiobacillus ferrooxidans: DNA sequence, enzyme purification, and characterization · PMID 8282728 · 4 records
• 3-Keto-5-aminohexanoate cleavage enzyme: a common fold for an uncommon Claisen-type condensation · PMID 21632536 · 8 records
• 3-Keto-5alpha-steroid Delta(1)-dehydrogenase from Rhodococcus erythropolis SQ1 and its orthologue in Mycobacterium tuberculosis H37Rv are highly specific enzymes that function in cholesterol… · PMID 18031290 · 23 records
• 4-Coumarate:coenzyme A ligase has the catalytic capacity to synthesize and reuse various (di)adenosine polyphosphates · PMID 12644689 · 14 records
• 4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB. A novel flavoprotein catalyzing Baeyer-Villiger oxidation of aromatic compounds · PMID 11322873 · 12 records
• 4-O-Methylglucaric Acid Production from Xylan with Uronic Acid Oxidase and Comparison to Glucaric Acid from Glucose · PMID 39831666 · 2 records
• 4-O-phosphoryl-L-threonine, a substrate of the pdxC(serC) gene product involved in vitamin B6 biosynthesis · PMID 8706854 · 6 records
• 5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs · PMID 27668519 · 19 records
• 6-Phospho-beta-galactosidases of gram-positive and 6-phospho-beta-glucosidase B of gram-negative bacteria: comparison of structure and function by kinetic and immunological methods and mutagenesis… · PMID 8309940 · 17 records
• 6-phosphogluconate dehydrogenase and the assay of uridine diphosphate glucose pyrophosphorylase in the cellular slime mould Dictyostelium discoideum · PMID 4672667 · 6 records
• 6-Phosphogluconate dehydrogenase: the mechanism of action investigated by a comparison of the enzyme from different species · PMID 9920387 · 7 records
• [Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa]. || Reinigung und Eigenschaften der Carnitindehydrogenase aus Pseudomonas aeruginosa · PMID 4302217 · 5 records
• A "moonlighting" dizinc aminopeptidase from Streptomyces griseus: mechanisms for peptide hydrolysis and the 4 x 10(10)-fold acceleration of the alternative phosphodiester hydrolysis · PMID 17105197 · 8 records
• A 38 kDa allylic alcohol dehydrogenase from the cultured cells of Nicotiana tabacum · PMID 11117876 · 11 records
• A 52-kDa leucyl aminopeptidase from treponema denticola is a cysteinylglycinase that mediates the second step of glutathione metabolism · PMID 18482986 · 5 records
• A 7-deoxyloganetic acid glucosyltransferase contributes a key step in secologanin biosynthesis in Madagascar periwinkle · PMID 24104568 · 6 records
• A 7-dimethylallyl tryptophan synthase from a fungal Neosartorya sp.: biochemical characterization and structural insight into the regioselective prenylation · PMID 24657051 · 5 records
• A [4Fe-4S] cluster resides at the active center of phosphomevalonate dehydratase, a key enzyme in the archaeal modified mevalonate pathway · PMID 36992929 · 1 record
• A bacterial spermidine biosynthetic pathway via carboxyaminopropylagmatine · PMID 37878710 · 11 records
• A BAHD acyltransferase catalyzing 19-O-acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids · PMID 29438577 · 8 records
• A bifunctional 3,5-epimerase/4-keto reductase for nucleotide-rhamnose synthesis in Arabidopsis · PMID 15020741 · 2 records
• A bifunctional salvage pathway for two distinct S-adenosylmethionine by-products that is widespread in bacteria, including pathogenic Escherichia coli · PMID 31950558 · 34 records
• A biosensor for all D-amino acids using evolved D-amino acid oxidase · PMID 18588925 · 19 records
• A Biotechnological Approach to Enzyme-Based Fertilisers: Immobilisation of Acid Phosphatases · PMID 42219665 · 3 records
• A broad specificity nucleoside kinase from Thermoplasma acidophilum · PMID 23161756 · 6 records
• A broader active site in Pyrococcus horikoshii CoA disulfide reductase accommodates larger substrates and reveals evidence of subunit asymmetry · PMID 29988575 · 8 records
• A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme · PMID 19666032 · 14 records
• A case for reverse protonation: identification of Glu160 as an acid/base catalyst in Thermoanaerobacterium saccharolyticum beta-xylosidase and detailed kinetic analysis of a site-directed mutant · PMID 12146939 · 10 records
• A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies · PMID 18342636 · 24 records
• A CDC25 homologue from rice functions as an arsenate reductase · PMID 17388894 · 8 records
• A cofactor-promiscuous HMGR from the Lyme disease pathogen illuminates diversity in bacterial isoprenoid biosynthesis · PMID 42615804 · 12 records
• A cold-active and thermostable alcohol dehydrogenase of a psychrotorelant from Antarctic seawater, Flavobacterium frigidimaris KUC-1 · PMID 17072683 · 10 records
• A cold-adapted and detergent-stable α-amylase from marine bacterium Photobacterium gaetbulicola Gung47^T · PMID 41964703 · 8 records
• A combinatorial strategy for HRV 3C protease engineering to achieve the N-terminal free cleavage · PMID 38521339 · 14 records
• A Comparative Study for the Incorporation of 8-oxo-dATP in DNA by Human DNA Polymerases · PMID 41898401 · 12 records
• A comparative study of influenza virus neuraminidases, using automated techniques · PMID 5816010 · 74 records
• A comparative study of several pancreatic ribonucleases: cleavage of dinucleoside phosphates and nucleoside cyclic phosphates · PMID 5724562 · 58 records
• A comparative study of the regulation of Ca2+ of the activities of the 2-oxoglutarate dehydrogenase complex and NAD+-isocitrate dehydrogenase from a variety of sources · PMID 7032511 · 18 records
• A comparison of selected physical properties of hepatic sorbitol dehydrogenases [L-iditol: NAD oxidoreductases] from four mammalian species · PMID 318236 · 36 records
• A comparison of two novel alcohol dehydrogenase enzymes (ADH1 and ADH2) from the extreme halophile Haloferax volcanii · PMID 22526808 · 7 records
• A comprehensive analysis of the NADP-malic enzyme gene family of Arabidopsis · PMID 16113210 · 7 records
• A comprehensive analysis of the peroxiredoxin reduction system in the Cyanobacterium Synechocystis sp. strain PCC 6803 reveals that all five peroxiredoxins are thioredoxin dependent · PMID 19820102 · 14 records
• A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes · PMID 25213862 · 9 records
• A conserved acidic residue in phenylalanine hydroxylase contributes to cofactor affinity and catalysis · PMID 25295853 · 8 records
• A conserved active-site threonine is important for both sugar and flavin oxidations of pyranose 2-oxidase · PMID 20089849 · 21 records
• A conserved C-terminal RXG motif in the NgBR subunit of cis-prenyltransferase is critical for prenyltransferase activity · PMID 28842490 · 10 records
• A conserved gene cluster rules anaerobic oxidative degradation of L-ornithine · PMID 19251850 · 7 records
• A conserved glutamate controls the commitment to acyl-adenylate formation in asparagine synthetase · PMID 20853825 · 16 records
• A conserved glutamate residue exhibits multifunctional catalytic roles in D-fructose-1,6-bisphosphate aldolases · PMID 11779856 · 5 records
• A conserved motif mediates both multimer formation and allosteric activation of phosphoglycerate mutase 5 · PMID 25012655 · 39 records
• A conserved phenylalanine of motif IV in superfamily 2 helicases is required for cooperative, ATP-dependent binding of RNA substrates in DEAD-box proteins · PMID 18332124 · 9 records
• A conserved residue of l-alanine dehydrogenase from Bacillus pseudofirmus, Lys-73, participates in the catalytic reaction through hydrogen bonding · PMID 29310857 · 16 records
• A conserved tyrosyl-glutamyl catalytic dyad in evolutionarily linked enzymes: carbapenam synthetase and beta-lactam synthetase · PMID 19371088 · 12 records
• A critical role for highly conserved Glu(610) residue of oligopeptidase B from Trypanosoma brucei in thermal stability · PMID 19819899 · 20 records
• A crucial active site network of titratable residues guides catalysis and NAD⁺ binding in human succinic semialdehyde dehydrogenase · PMID 39731543 · 12 records
• A crystal structure of 2-hydroxybiphenyl 3-monooxygenase with bound substrate provides insights into the enzymatic mechanism · PMID 26275805 · 12 records
• A Dedicated Type II NADPH Dehydrogenase Performs the Penultimate Step in the Biosynthesis of Vitamin K1 in Synechocystis and Arabidopsis · PMID 26023160 · 2 records
• A direct substrate-substrate interaction found in the kinase domain of the bifunctional enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase · PMID 17499765 · 6 records
• A direct, real-time, spectrophotometric assay for measuring ENPP1-catalyzed cGAMP hydrolysis · PMID 42055331 · 6 records
• A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis · PMID 25431972 · 10 records
• A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes · PMID 24463512 · 23 records
• A family of S-methylmethionine-dependent thiol/selenol methyltransferases. Role in selenium tolerance and evolutionary relation · PMID 10026151 · 3 records
• A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines · PMID 11927571 · 35 records
• A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism · PMID 20448045 · 5 records
• A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax · PMID 18519562 · 13 records
• A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity · PMID 17344335 · 8 records
• A functional genomics approach to (iso)flavonoid glycosylation in the model legume Medicago truncatula · PMID 17437063 · 13 records
• A functional genomics investigation of allelochemical biosynthesis in Sorghum bicolor root hairs · PMID 17998204 · 6 records
• A functional role for a flexible loop containing Glu182 in the class II fructose-1,6-bisphosphate aldolase from Escherichia coli · PMID 11779234 · 18 records
• A Fungal p-Terphenyl Prenyltransferase for Regioselective C-Prenylation of Flavonoids and Other Compounds Bearing ortho-Dihydroxyphenyl… · PMID 42083790 · 8 records
• A gene cluster involved in degradation of substituted salicylates via ortho cleavage in Pseudomonas sp. strain MT1 encodes enzymes specifically adapted for transformation of 4-methylcatechol and… · PMID 17172348 · 21 records
• A gene cluster responsible for alkylaldoxime metabolism coexisting with nitrile hydratase and amidase in Rhodococcus globerulus A-4 · PMID 14556637 · 14 records
• A gene encoding L-methionine gamma-lyase is present in Enterobacteriaceae family genomes: identification and characterization of Citrobacter freundii L-methionine gamma-lyase · PMID 15901718 · 14 records
• A genetically encoded bifunctional enzyme mitigates redox imbalance and lipotoxicity · PMID 41699300 · 2 records
• A Glutamate-Substituted Mutant Mimics the Phosphorylated and Active Form of Guanylyl Cyclase-A · PMID 28416574 · 1 record
• A Golgi-localized N-methyltransferase and reversible aldo-keto reductases coordinate dual terminal routes in galanthamine biosynthesis · PMID 42364649 · 2 records
• A Grapevine Anthocyanin Acyltransferase, Transcriptionally Regulated by VvMYBA, Can Produce Most Acylated Anthocyanins Present in Grape Skins · PMID 26395841 · 9 records
• A Growth-Based, High-Throughput Selection Platform Enables Remodeling of 4-Hydroxybenzoate Hydroxylase Active Site · PMID 34295569 · 10 records
• A GTP-dependent vertebrate-type phosphoenolpyruvate carboxykinase from Mycobacterium smegmatis · PMID 11278451 · 13 records
• A heterodimeric glutathione S-transferase that stereospecifically breaks lignin's β(R)-aryl ether bond reveals the diversity of bacterial β-etherases · PMID 30541921 · 6 records
• A hexanucleotide sequence (dC1-dC6 tract) restricts the dC-specific cleavage of single-stranded DNA by endonuclease IV of bacteriophage T4 · PMID 17940096 · 20 records
• A high-affinity adenosine kinase from Anopheles gambiae · PMID 21247194 · 10 records
• A high-throughput screen for porphyrin metal chelatases: application to the directed evolution of ferrochelatases for metalloporphyrin biosynthesis · PMID 15300829 · 14 records
• A highly active adipyl-cephalosporin acylase obtained via rational randomization · PMID 17922842 · 17 records
• A highly active decarboxylating dehydrogenase with rationally inverted coenzyme specificity · PMID 8524825 · 16 records
• A highly dynamic mononuclear non-heme iron enzyme for the two-step isonitrile biosynthesis · PMID 41587996 · 4 records
• A Highly Stable D-Amino Acid Oxidase of the Thermophilic Bacterium Rubrobacter xylanophilus · PMID 25217016 · 5 records
• A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction · PMID 21698192 · 4 records
• A homodimeric bacterial exo-β-1,3-glucanase derived from moose rumen microbiome shows a structural framework similar to yeast exo-β-1,3-glucanases · PMID 33375982 · 8 records
• A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease · PMID 9553139 · 6 records
• A human-like glutaminase-free asparaginase is highly efficacious in ASNS^low leukemia and solid cancer mouse xenograft models · PMID 39709177 · 3 records
• A hydrolase from Serratia liquefaciens IMD717 with esterase, dehalogenase and N-deformylase activities · PMID 42009829 · 4 records
• A hyperactive NAD(P)H:Rubredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus · PMID 10464233 · 7 records
• A Hyperthermostable Archaeal GH78 Rhamnosidase Efficiently Hydrolyzes Flavonoid Glycosides for Juice Debittering · PMID 41664936 · 4 records
• A hyperthermostable D-ribose-5-phosphate isomerase from Pyrococcus horikoshii characterization and three-dimensional structure · PMID 12057201 · 8 records
• A key amino acid responsible for substrate selectivity of monoamine oxidase A and B · PMID 9162023 · 26 records
• A kinetic comparison of asparagine synthetase isozymes from higher plants · PMID 21276727 · 22 records
• A kinetic comparison of partially purified rat liver Golgi and rat serum galactosyltransferases · PMID 6426461 · 12 records
• A kinetic comparison of the homologous proteases astacin and meprin A · PMID 8161197 · 15 records
• A kinetic study of NMC-A beta-lactamase, an Ambler class A carbapenemase also hydrolyzing cephamycins · PMID 8807798 · 16 records
• A kinetic study of pig liver glucose dehydrogenase · PMID 8012 · 8 records
• A kinetic study of the hydrolysis of the N-tosylalanine ester of 3-hydroxy-5-phenylpyrrole and related compounds by human leukocyte elastase · PMID 7487054 · 34 records
• A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase · PMID 18370401 · 8 records
• A la carte bioprospecting of substrate-selective laccases via high-throughput computational enzyme-substrate interaction profiling · PMID 41676955 · 5 records
• A large hinge bending domain rotation is necessary for the catalytic function of Escherichia coli 5'-nucleotidase · PMID 15709736 · 5 records
• A Low-Temperature-Active Pectate Lyase from a Marine Bacterium for Orange Juice Clarification · PMID 40142526 · 4 records
• A lung type prostaglandin F synthase is expressed in bovine liver: cDNA sequence and expression in E. coli · PMID 1339268 · 8 records
• A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites · PMID 19401154 · 12 records
• A mechanism of resistance to methotrexate. NADPH but not NADH stimulation of methotrexate binding to dihydrofolate reductase · PMID 6882460 · 8 records
• A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem · PMID 15588826 · 3 records
• A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes · PMID 23831062 · 29 records
• A modified consensus approach to mutagenesis inverts the cofactor specificity of Bacillus stearothermophilus lactate dehydrogenase · PMID 16012175 · 9 records
• A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1 · PMID 11756418 · 5 records
• A monofunctional-like mutant of DNA glycosylase NTHL1 changes the dynamics of DNA repair during acute oxidative stress · PMID 41763309 · 4 records
• A monomer-dimer switch modulates the activity of plant adenosine kinase · PMID 40063605 · 23 records
• A multi-dimensional engineering strategy integrating computational design, self-cyclization and whole cell biocatalysis for efficient epilactose production · PMID 42633114 · 4 records
• A multifunctional fermentative alcohol dehydrogenase from the strict aerobe Alcaligenes eutrophus: purification and properties · PMID 6378632 · 18 records
• A multifunctional true caffeoyl coenzyme A O-methyltransferase enzyme participates in the biosynthesis of polymethoxylated flavones in citrus · PMID 37086474 · 10 records
• A mutant Escherichia coli tyrosyl-tRNA synthetase utilizes the unnatural amino acid azatyrosine more efficiently than tyrosine · PMID 11006270 · 4 records
• A naturally occurring standalone TrpB enzyme provides insights into allosteric communication within tryptophan synthase · PMID 40100167 · 8 records
• A new aldehyde oxidase catalyzing the conversion of glycolaldehyde to glycolate from Burkholderia sp. AIU 129 · PMID 25283808 · 7 records
• A new branch of mammalian vitamin B₆ metabolism: AKR1C-mediated conversion of pyridoxal to pyridoxine and 4-pyridoxolactone · PMID 41741972 · 7 records
• A new cold-adapted beta-D-galactosidase from the Antarctic Arthrobacter sp. 32c - gene cloning, overexpression, purification and properties · PMID 19631003 · 11 records
• A new D-2-hydroxyacid dehydrogenase with dual coenzyme-specificity from Haloferax mediterranei, sequence analysis and heterologous overexpression · PMID 17049749 · 13 records
• A new family of type III polyketide synthases in Mycobacterium tuberculosis · PMID 12941968 · 6 records
• A new marine bacterial laccase with chloride-enhancing, alkaline-dependent activity and dye decolorization ability · PMID 22377476 · 10 records
• A new member of the alkaline phosphatase superfamily with a formylglycine nucleophile: structural and kinetic characterisation of a phosphonate monoester hydrolase/phosphodiesterase from Rhizobium… · PMID 18793651 · 21 records
• A new member of the DMATS superfamily from Aspergillus niger catalyzes prenylations of both tyrosine and tryptophan derivatives · PMID 24970457 · 10 records
• A new NAD⁺-dependent glyceraldehyde dehydrogenase obtained by rational design of l-lactaldehyde dehydrogenase from Escherichia coli · PMID 27671251 · 7 records
• A new nicotinamide-adenine dinucleotide-dependent hydroaromatic dehydrogenase of Lactobacillus plantarum and its role in formation of (minus)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate · PMID 4375976 · 10 records
• A new subfamily of agmatinases present in methanogenic Archaea is Fe(II) dependent · PMID 22439800 · 5 records
• A new type of peroxisomal acyl-coenzyme A synthetase from Arabidopsis thaliana has the catalytic capacity to activate biosynthetic precursors of jasmonic acid · PMID 15677481 · 9 records
• A Newly Determined Member of the meso-Diaminopimelate Dehydrogenase Family with a Broad Substrate Spectrum · PMID 28341677 · 12 records
• A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity · PMID 15178494 · 32 records
• A non-specific aminopeptidase from Aspergillus · PMID 10899618 · 7 records
• A novel 4-hydroxycoumarin biosynthetic pathway · PMID 19757094 · 9 records
• A novel alpha-glucosidase from the acidophilic archaeon Ferroplasma acidiphilum strain Y with high transglycosylation activity and an unusual catalytic nucleophile · PMID 15954864 · 16 records
• A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria · PMID 8550422 · 5 records
• A novel amylolytic enzyme from Thermotoga maritima, resembling cyclodextrinase and alpha-glucosidase, that liberates glucose from the reducing end of the substrates · PMID 12127967 · 7 records
• A novel approach to the characterization of substrate specificity in short/branched chain Acyl-CoA dehydrogenase · PMID 12855692 · 21 records
• A novel archaebacterial NAD+-dependent alcohol dehydrogenase. Purification and properties · PMID 3115775 · 18 records
• A novel assay method for an amino acid racemase reaction based on circular dichroism · PMID 15796715 · 6 records
• A novel beta-lactamase activity from a penicillin-binding protein of Treponema pallidum and why syphilis is still treatable with penicillin · PMID 14747460 · 12 records
• A novel beta-N-acetyl-D-hexosaminidase from the insect Ostrinia furnacalis (Guenée) · PMID 18959754 · 3 records
• A Novel Bifunctional Amino Acid Racemase With Multiple Substrate Specificity, MalY From Lactobacillus sakei LT-13: Genome-Based Identification and Enzymological Characterization · PMID 29563907 · 3 records
• A novel biosensor for measuring plasmin activity · PMID 42293733 · 6 records
• A novel carbohydrate:acceptor oxidoreductase from Microdochium nivale · PMID 11179980 · 5 records
• A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity · PMID 25572472 · 16 records
• A Novel Cold-Adapted Leucine Dehydrogenase from Antarctic Sea-Ice Bacterium Pseudoalteromonas sp. ANT178 · PMID 30275355 · 8 records
• A novel dCMP methylase by engineering thymidylate synthase · PMID 9398324 · 13 records
• A novel efficient β-glucanase from a paddy soil microbial metagenome with versatile activities · PMID 26877766 · 23 records
• A novel F(420) -dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents · PMID 23240649 · 12 records
• A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals · PMID 21507950 · 10 records
• A novel hyperthermophilic archaeal glyoxylate reductase from Thermococcus litoralis. Characterization, gene cloning, nucleotide sequence and expression in Escherichia coli · PMID 11532010 · 3 records
• A novel L-aspartate dehydrogenase from the mesophilic bacterium Pseudomonas aeruginosa PAO1: molecular characterization and application for L-aspartate production · PMID 21468714 · 10 records
• A novel L-xylulose reductase essential for L-arabinose catabolism in Trichoderma reesei · PMID 23506391 · 5 records
• A novel mammalian flavin-dependent histone demethylase · PMID 19407342 · 10 records
• A novel meso-Diaminopimelate dehydrogenase from Symbiobacterium thermophilum: overexpression, characterization, and potential for D-amino acid synthesis · PMID 23023754 · 9 records
• A novel metagenome-derived beta-galactosidase: gene cloning, overexpression, purification and characterization · PMID 20614217 · 8 records
• A Novel N-Methyltransferase in Arabidopsis Appears to Feed a Conserved Pathway for Nicotinate Detoxification among Land Plants and Is Associated with Lignin Biosynthesis · PMID 28533213 · 16 records
• A novel NAD(P)H-dependent carbonyl reductase specifically expressed in the thyroidectomized chicken fatty liver: catalytic properties and crystal structure · PMID 26206323 · 21 records
• A novel NADPH:diamide oxidoreductase activity in arabidopsis thaliana P1 zeta-crystallin · PMID 10848984 · 15 records
• A novel nucleotide kinase encoded by gene 1.7 of bacteriophage T7 · PMID 20497505 · 19 records
• A novel o-aminophenol oxidase responsible for formation of the phenoxazinone chromophore of grixazone · PMID 16282322 · 10 records
• A novel O-phospho-L-serine sulfhydrylation reaction catalyzed by O-acetylserine sulfhydrylase from Aeropyrum pernix K1 · PMID 12965218 · 6 records
• A novel plant enzyme with dual activity: an atypical Nudix hydrolase and a dipeptidyl peptidase III · PMID 27467751 · 12 records
• A novel polyamine acyltransferase responsible for the accumulation of spermidine conjugates in Arabidopsis seed · PMID 19168716 · 7 records
• A Novel Polyamine Oxidase from Kluyveromyces marxianus with Potential for Total Polyamine Determination · PMID 42645329 · 6 records
• A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family · PMID 3182871 · 15 records
• A Novel Screening System to Characterize and Engineer Quorum Quenching Lactonases · PMID 39825575 · 43 records
• A novel single-stranded DNA-specific 3'-5' exonuclease, Thermus thermophilus exonuclease I, is involved in several DNA repair pathways · PMID 20457749 · 10 records
• A novel subfamily of monomeric inorganic pyrophosphatases in photosynthetic eukaryotes · PMID 16313235 · 7 records
• A novel subtype of class II alcohol dehydrogenase in rodents. Unique Pro(47) and Ser(182) modulates hydride transfer in the mouse enzyme · PMID 10514444 · 66 records
• A novel thermostable arylesterase from the archaeon Sulfolobus solfataricus P1: purification, characterization, and expression · PMID 18931117 · 11 records
• A novel thermostable D-amino acid oxidase of the thermophilic fungus Rasamsonia emersonii strain YA · PMID 31420577 · 5 records
• A novel thermostable esterase from the thermoacidophilic archaeon Sulfolobus tokodaii strain 7 · PMID 15212797 · 3 records
• A novel tryptophan synthase beta-subunit from the hyperthermophile Thermotoga maritima. Quaternary structure, steady-state kinetics, and putative physiological role · PMID 11756459 · 10 records
• A novel twist on molecular interactions between thioredoxin and nicotinamide adenine dinucleotide phosphate-dependent thioredoxin reductase · PMID 24123219 · 27 records
• A Novel Type II NAD+-Specific Isocitrate Dehydrogenase from the Marine Bacterium Congregibacter litoralis KT71 · PMID 25942017 · 7 records
• A novel white laccase from Pleurotus ostreatus · PMID 9395457 · 11 records
• A novel zinc-dependent D-serine dehydratase from Saccharomyces cerevisiae · PMID 17937657 · 8 records
• A novel α-L-arabinofuranosidase of family 43 glycoside hydrolase (Ct43Araf) from Clostridium thermocellum · PMID 24039988 · 16 records
• A Novel β/ε Subunit Combination Expands the Tri-Subunit Acyl-CoA Carboxylase Repertoire in Streptomyces coelicolor · PMID 42075131 · 11 records
• A p-coumaroyl esterase from Rhizoctonia solani with a pronounced chlorogenic acid esterase activity · PMID 28159727 · 4 records
• A pantothenate kinase from Staphylococcus aureus refractory to feedback regulation by coenzyme A · PMID 15548531 · 4 records
• A paradigm shift for the amino acid editing mechanism of human cytoplasmic leucyl-tRNA synthetase · PMID 19702327 · 6 records
• A pentose bisphosphate pathway for nucleoside degradation in Archaea · PMID 25822915 · 9 records
• A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis · PMID 23387521 · 16 records
• A phosphate-binding histidine of binuclear metallophosphodiesterase enzymes is a determinant of 2',3'-cyclic nucleotide phosphodiesterase activity · PMID 18757371 · 8 records
• A phylogenomic analysis of the shikimate dehydrogenases reveals broadscale functional diversification and identifies one functionally distinct subclass · PMID 18669580 · 14 records
• A point mutation in ftmD blocks the fumitremorgin biosynthetic pathway in Aspergillus fumigatus strain Af293 · PMID 23649274 · 4 records
• A Portable Colorimetric Device for Rapid Bacterial Detection with Cleavable Functional Nucleic Acid Probes for A Common Bacterial Endoribonuclease · PMID 42148598 · 4 records
• A positively charged amino acid at position 129 in nitrilase from Rhodococcus rhodochrous ATCC 33278 is an essential residue for the activity with meta-substituted benzonitriles · PMID 19903476 · 11 records
• A Potent and Selective Quinolone-Based PTPN22 Inhibitor with Improved Immunotherapeutic Activity · PMID 42388138 · 4 records
• A Potent Quinone Reductase Encoded by ywqN (Qnr1) Protects Bacillus subtilis from Oxygen Radical Genotoxicity · PMID 41752478 · 5 records
• A preliminary characterization of the cytosolic glutathione transferase proteome from Drosophila melanogaster · PMID 22082028 · 65 records
• A promiscuous beta-glucosidase is involved in benzoxazinoid deglycosylation in Lamium galeobdolon · PMID 30336442 · 7 records
• A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion · PMID 29950589 · 6 records
• A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro · PMID 29101342 · 4 records
• A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase · PMID 27570878 · 12 records
• A reciprocal single mutation affects the metal requirement of 3-deoxy-D-manno-2-octulosonate-8-phosphate (KDO8P) synthases from Aquifex pyrophilus and Escherichia coli · PMID 15308670 · 15 records
• A residue in the S2 subsite controls substrate selectivity of matrix metalloproteinase-2 and matrix metalloproteinase-9 · PMID 12591933 · 12 records
• A reverse TCA cycle 2-oxoacid:ferredoxin oxidoreductase that makes C-C bonds from CO₂ · PMID 31080943 · 10 records
• A robust metallo-oxidase from the hyperthermophilic bacterium Aquifex aeolicus · PMID 17451433 · 18 records
• A role for catalase-peroxidase large loop 2 revealed by deletion mutagenesis: control of active site water and ferric enzyme reactivity · PMID 25674665 · 53 records
• A role for glutamate-333 of Saccharomyces cerevisiae cystathionine γ-lyase as a determinant of specificity · PMID 24291053 · 33 records
• A role for glutamine 183 in the folate oxidative half-reaction of methylenetetrahydrofolate reductase from Escherichia coli · PMID 29407039 · 13 records
• A role for His-160 in peroxide inhibition of S. cerevisiae S-formylglutathione hydrolase: evidence for an oxidation sensitive motif · PMID 22906720 · 15 records
• A root-expressed L-phenylalanine:4-hydroxyphenylpyruvate aminotransferase is required for tropane alkaloid biosynthesis in Atropa belladonna · PMID 25228340 · 9 records
• A Scots pine 4-coumarate:CoA ligase with high cinnamic acid affinity is the primary candidate for pinosylvin biosynthesis · PMID 41709713 · 32 records
• A second dihydroorotate dehydrogenase (Type A) of the human pathogen Enterococcus faecalis: expression, purification, and steady-state kinetic mechanism · PMID 10775458 · 6 records
• A second GDP-L-galactose phosphorylase in arabidopsis en route to vitamin C. Covalent intermediate and substrate requirements for the conserved reaction · PMID 18463094 · 18 records
• A second-sphere variant of cytochrome P450 PbdA improves turnover and apparent coupling in veratrate oxidation · PMID 42720817 · 3 records
• A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts · PMID 12813046 · 21 records
• A Selective Phenyl Azo Acetate Substrate for Enhanced Carbonic Anhydrase Functional Analysis · PMID 42255016 · 6 records
• A set of regioselective O-methyltransferases gives rise to the complex pattern of methoxylated flavones in sweet basil · PMID 22923679 · 22 records
• A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet · PMID 21668645 · 12 records
• A sialyltransferase mutant with decreased donor hydrolysis and reduced sialidase activities for directly sialylating LewisX · PMID 22583967 · 17 records
• A simple assay for 3-deoxy-d-manno-octulosonate cytidylyltransferase and its use as a pathway screen · PMID 21669179 · 5 records
• A simple two step procedure for purification of the catalytic domain of chicken tryptophan hydroxylase 1 in a form suitable for crystallization · PMID 18055219 · 4 records
• A single amino acid change is responsible for evolution of acyltransferase specificity in bacterial methionine biosynthesis · PMID 18216013 · 22 records
• A single amino acid limits the substrate specificity of Thermus thermophilus uridine-cytidine kinase to cytidine · PMID 21539325 · 12 records
• A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi · PMID 12121990 · 8 records
• A single Phe54Tyr substitution improves the catalytic activity and thermostability of Trigonopsis variabilis D-amino acid oxidase · PMID 19909828 · 6 records
• A single residue at the active site of CD38 determines its NAD cyclizing and hydrolyzing activities · PMID 11278881 · 33 records
• A single residue determines substrate preference in benzylisoquinoline alkaloid N-methyltransferases · PMID 31765874 · 16 records
• A single residue in leucyl-tRNA synthetase affecting amino acid specificity and tRNA aminoacylation · PMID 17378584 · 31 records
• A single-residue exchange gives human recombinant beta beta alcohol dehydrogenase gamma gamma isozyme properties · PMID 1572355 · 15 records
• A solanesyl-diphosphate synthase localizes in glycosomes of Trypanosoma cruzi · PMID 17062572 · 6 records
• A Solanum torvum GH3 β-glucosidase expressed in Pichia pastoris catalyzes the hydrolysis of furostanol glycoside · PMID 27055587 · 3 records
• A soluble metalloendopeptidase from rat brain. Purification of the enzyme and determination of specificity with synthetic and natural peptides · PMID 6349998 · 11 records
• A specialized citric acid cycle requiring succinyl-coenzyme A (CoA):acetate CoA-transferase (AarC) confers acetic acid resistance on the acidophile Acetobacter aceti · PMID 18502856 · 7 records
• A stable GH31 α-glucosidase as a model system for the study of mutations leading to human glycogen storage disease type II · PMID 39995088 · 9 records
• A steric gate prevents mutagenic dATP incorporation opposite 8-oxo-deoxyguanosine in mitochondrial DNA polymerases · PMID 40070220 · 30 records
• A strategically positioned cation is crucial for efficient catalysis by chorismate mutase · PMID 10960481 · 3 records
• A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis · PMID 27821871 · 4 records
• A structural basis for substrate selectivity and stereoselectivity in octopine dehydrogenase from Pecten maximus · PMID 18599075 · 8 records
• A structural determinant of mycophenolic acid resistance in eukaryotic inosine 5'-monophosphate dehydrogenases · PMID 31675145 · 8 records
• A Structure-Guided Switch in the Regioselectivity of a Tryptophan Halogenase · PMID 26840773 · 3 records
• A study of human furin specificity using synthetic peptides derived from natural substrates, and effects of potassium ions · PMID 19477160 · 114 records
• A study of the kinetics and mechanism of rabbit muscle L-glycerol 3-phosphate dehydrogenase · PMID 4377219 · 32 records
• A study of the kinetics and mechanism of yeast alcohol dehydrogenase with a variety of substrates · PMID 4352908 · 13 records
• A study on reducing substrates of manganese-oxidizing peroxidases from Pleurotus eryngii and Bjerkandera adusta · PMID 9654123 · 34 records
• A substrate-bound structure of cyanobacterial biliverdin reductase identifies stacked substrates as critical for activity · PMID 28169272 · 17 records
• A substrate-induced switch in the reaction mechanism of a thermophilic esterase: kinetic evidences and structural basis · PMID 14617621 · 22 records
• A sugar isomerization reaction established on various (βα)₈-barrel scaffolds is based on substrate-assisted catalysis · PMID 23109729 · 4 records
• A sulfotransferase from a gut microbe acts on diverse phenolic sulfate compounds, including acetaminophen sulfate · PMID 41552834 · 8 records
• A survey of the kinetic parameters of class C beta-lactamases. Cephalosporins and other beta-lactam compounds · PMID 3264155 · 86 records
• A switch in the kinase domain of rat testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase · PMID 10493801 · 10 records
• A Tailor-Made Deazaflavin-Mediated Recycling System for Artificial Nicotinamide Cofactor Biomimetics · PMID 34557329 · 20 records
• A tailored CoA ligase-N-acyltransferase cascade for on-DNA amide bond formation gives access to broad substrate scope · PMID 42630299 · 4 records
• A tale of two isomerases: compact versus extended active sites in ketosteroid isomerase and phosphoglucose isomerase · PMID 21970785 · 16 records
• A thermostable and highly active fungal GH3 β-glucosidase generated by random and saturation mutagenesis · PMID 39971319 · 8 records
• A thermostable triple mutant of pyranose 2-oxidase from Trametes multicolor with improved properties for biotechnological applications · PMID 19291706 · 16 records
• A thermostable variant of fructose bisphosphate aldolase constructed by directed evolution also shows increased stability in organic solvents · PMID 15531627 · 9 records
• A three-dimensional model of the neprilysin 2 active site based on the X-ray structure of neprilysin. Identification of residues involved in substrate hydrolysis and inhibitor binding of neprilysin… · PMID 15294904 · 6 records
• A tyrosine aminotransferase involved in rosmarinic acid biosynthesis in Prunella vulgaris L · PMID 28687763 · 10 records
• A Tyrosine Residue Along with a Glutamic Acid of the Omega-Like Loop Governs the Beta-Lactamase Activity of MSMEG_4455 in Mycobacterium smegmatis · PMID 28421415 · 14 records
• A UDP-glucose:isoflavone 7-O-glucosyltransferase from the roots of soybean (glycine max) seedlings. Purification, gene cloning, phylogenetics, and an implication for an alternative strategy of… · PMID 17565994 · 20 records
• A unique homodimeric NAD⁺-linked isocitrate dehydrogenase from the smallest autotrophic eukaryote Ostreococcus tauri · PMID 25724193 · 8 records
• A unique insertion in the CP1 domain of Giardia lamblia leucyl-tRNA synthetase · PMID 19170608 · 13 records
• A unique substrate recognition profile for matrix metalloproteinase-2 · PMID 11694539 · 52 records
• A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle · PMID 38287013 · 10 records
• A universal polyphosphate kinase powers in vitro transcription · PMID 41507187 · 8 records
• A Val292 substitution combined with an alanine duplication (ADUP) in the Ω loop of ADC β-lactamase confers reduced susceptibility to advanced β-lactam agents, including cefiderocol · PMID 41949313 · 12 records
• A Versatile Protein Scaffold Engineered for the Hierarchical Assembly of Robust and Highly Active Enzymes · PMID 39985242 · 4 records
• A zinc-containing mannitol-2-dehydrogenase from Leuconostoc pseudomesenteroides ATCC 12291: purification of the enzyme and cloning of the gene · PMID 12560988 · 4 records
• AAC(3)-XI, a new aminoglycoside 3-N-acetyltransferase from Corynebacterium striatum · PMID 26149994 · 3 records
• aac(6')-Iaq, a novel aminoglycoside acetyltransferase gene identified from an animal isolate Brucella intermedia DW0551 · PMID 40134786 · 5 records
• Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1 · PMID 18675810 · 3 records
• Acceptor substrate selectivity and kinetic mechanism of Bacillus subtilis TagA · PMID 16953575 · 7 records
• Access to the carbamate tunnel of carbamoyl phosphate synthetase · PMID 15081891 · 52 records
• Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase · PMID 18795799 · 4 records
• ACE2-like Catalytic Activity in Anti-SARS-CoV-2 Spike Protein Monoclonal Antibodies · PMID 42796707 · 5 records
• Acetolactate synthase from Bacillus subtilis serves as a 2-ketoisovalerate decarboxylase for isobutanol biosynthesis in Escherichia coli · PMID 19684168 · 10 records
• Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates · PMID 12665427 · 9 records
• Acetylcholinesterase peripheral anionic site degeneracy conferred by amino acid arrays sharing a common core · PMID 8119978 · 19 records
• Acetyltransfer in natural product biosynthesis--functional cloning and molecular analysis of vinorine synthase · PMID 15110860 · 10 records
• Acetyltransfer precedes uridylyltransfer in the formation of UDP-N-acetylglucosamine in separable active sites of the bifunctional GlmU protein of Escherichia coli · PMID 8555230 · 15 records
• Acid stabilization of Bacillus licheniformis alpha amylase through introduction of mutations · PMID 18626642 · 20 records
• Acidic residues important for substrate binding and cofactor reactivity in eukaryotic ornithine decarboxylase identified by alanine scanning mutagenesis · PMID 7744828 · 13 records
• Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase · PMID 19861168 · 41 records
• Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein · PMID 12603323 · 5 records
• Actions of two serine proteases from Trimeresurus jerdonii venom on chromogenic substrates and fibrinogen · PMID 12091097 · 5 records
• Activating a zymogen without proteolytic processing: mutation of Lys15 and Asn194 activates trypsinogen · PMID 9819212 · 22 records
• Activation and inhibition of pyruvate carboxylase from Rhizobium etli · PMID 21958066 · 32 records
• Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding · PMID 17973628 · 20 records
• Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa · PMID 19490111 · 12 records
• Activation mechanism of recombinant Der p 3 allergen zymogen: contribution of cysteine protease Der p 1 and effect of propeptide glycosylation · PMID 18725410 · 5 records
• Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release · PMID 19385665 · 12 records
• Activation of Latent Dihydroorotase from Aquifex aeolicus by Pressure · PMID 27746403 · 11 records
• Activation of Sulfolobus solfataricus alcohol dehydrogenase by modification of cysteine residue 38 with iodoacetic acid · PMID 8555238 · 27 records
• Activation of thiamin diphosphate and FAD in the phosphatedependent pyruvate oxidase from Lactobacillus plantarum · PMID 9582325 · 8 records
• Active site and loop 4 movements within human glycolate oxidase: implications for substrate specificity and drug design · PMID 18215067 · 3 records
• Active site architecture of an acetyl xylan esterase indicates a novel cold adaptation strategy · PMID 34058201 · 28 records
• Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase · PMID 28157283 · 6 records
• Active site labeling of the gentamicin resistance enzyme AAC(6')-APH(2") by the lipid kinase inhibitor wortmannin · PMID 11514228 · 17 records
• Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis · PMID 23298222 · 12 records
• Active site mapping of MraY, a member of the polyprenyl-phosphate N-acetylhexosamine 1-phosphate transferase superfamily, catalyzing the first membrane step of peptidoglycan biosynthesis · PMID 18672909 · 30 records
• Active site mutants of Escherichia coli citrate synthase. Effects of mutations on catalytic and allosteric properties · PMID 8276829 · 7 records
• Active site mutants of Escherichia coli dethiobiotin synthetase: effects of mutations on enzyme catalytic and structural properties · PMID 9125495 · 25 records
• Active site mutants of the "non-hydrolyzing" UDP-N-acetylglucosamine 2-epimerase from Escherichia coli · PMID 15210128 · 6 records
• Active site of Zn(2+)-dependent sn-glycerol-1-phosphate dehydrogenase from Aeropyrum pernix K1 · PMID 15876564 · 18 records
• Active site residues and mechanism of UDP-glucose dehydrogenase · PMID 14686915 · 9 records
• Active site residues of glutamate racemase · PMID 11371180 · 8 records
• Active site specificity of plasmepsin II · PMID 10548045 · 70 records
• Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase · PMID 11786019 · 9 records
• Active-site mapping of bovine and human blood coagulation serine proteases using synthetic peptide 4-nitroanilide and thio ester substrates · PMID 6370301 · 131 records
• Active-site structure of class IV adenylyl cyclase and transphyletic mechanism · PMID 21094652 · 43 records
• Active-site-mutagenesis study of rat liver betaine-homocysteine S-methyltransferase · PMID 12487625 · 24 records
• Activities of recombinant human bleomycin hydrolase on bleomycins and engineered analogues revealing new opportunities to overcome bleomycin-induced pulmonary toxicity · PMID 29730026 · 7 records
• Activity enhancement of CotA laccase by hydrophilic engineering, histidine tag optimization and static culture · PMID 29301022 · 7 records
• Activity Essential Residue Analysis of Taxoid 10β-O-Acetyl Transferase for Enzymatic Synthesis of Baccatin · PMID 29797298 · 14 records
• Activity modulation of the oligopeptidase B from Serratia proteamaculans by site-directed mutagenesis of amino acid residues surrounding catalytic triad histidine · PMID 28554571 · 30 records
• Activity of 3-ketosteroid 9α-hydroxylase (KshAB) indicates cholesterol side chain and ring degradation occur simultaneously in Mycobacterium tuberculosis · PMID 21987574 · 5 records
• Activity of a second Trypanosoma brucei hexokinase is controlled by an 18-amino-acid C-terminal tail · PMID 17028241 · 14 records
• Activity of ADAM17 (a disintegrin and metalloprotease 17) is regulated by its noncatalytic domains and secondary structure of its substrates · PMID 23779109 · 37 records
• Activity of hyperthermophilic glycosynthases is significantly enhanced at acidic pH · PMID 12859194 · 19 records
• Acyl carrier protein synthases from gram-negative, gram-positive, and atypical bacterial species: Biochemical and structural properties and physiological implications · PMID 16788183 · 28 records
• Acyl carrier proteins from sunflower (Helianthus annuus L.) seeds and their influence on FatA and FatB acyl-ACP thioesterase activities · PMID 27095109 · 21 records
• Acyl coenzyme A thioesterase Them5/Acot15 is involved in cardiolipin remodeling and fatty liver development · PMID 22586271 · 12 records
• Acyl glucuronidation of fluoroquinolone antibiotics by the UDP-glucuronosyltransferase 1A subfamily in human liver microsomes · PMID 15769885 · 12 records
• Acyl transfer activity of an amidase from Rhodococcus sp. strain R312: formation of a wide range of hydroxamic acids · PMID 9687439 · 56 records
• Acyl-ACP thioesterases from Camelina sativa: cloning, enzymatic characterization and implication in seed oil fatty acid composition · PMID 25212866 · 8 records
• Acyl-ACP thioesterases from castor (Ricinus communis L.): an enzymatic system appropriate for high rates of oil synthesis and accumulation · PMID 20382402 · 8 records
• Acyl-ACP thioesterases from macadamia (Macadamia tetraphylla) nuts: cloning, characterization and their impact on oil composition · PMID 21071236 · 8 records
• Acyl-adenylate motif of the acyl-adenylate/thioester-forming enzyme superfamily: a site-directed mutagenesis study with the Pseudomonas sp. strain CBS3 4-chlorobenzoate:coenzyme A ligase · PMID 9398293 · 15 records
• Acylamino acid-releasing enzyme from the thermophilic archaeon Pyrococcus horikoshii · PMID 9651372 · 16 records
• Adaptation of a thermophilic enzyme, 3-isopropylmalate dehydrogenase, to low temperatures · PMID 11297666 · 20 records
• Adaptation of Folding and Function of a Nuclease from the Cold Deep Sea · PMID 41443464 · 4 records
• Adaptation of the Romanomermis culicivorax CCA-Adding Enzyme to Miniaturized Armless tRNA Substrates · PMID 33260740 · 12 records
• Additional data about thermolysin specificity in buffer- and glycerol-containing media · PMID 9003446 · 12 records
• Additivity of the Stabilization Effect of Single Amino Acid Substitutions in Triple Mutants of Recombinant Formate Dehydrogenase from the Soybean Glycine max · PMID 26483960 · 6 records
• Adenine binding mode is a key factor in triggering the early release of NADH in coenzyme A-dependent methylmalonate semialdehyde dehydrogenase · PMID 22782904 · 18 records
• Adenine nucleotide-dependent and redox-independent control of mitochondrial malate dehydrogenase activity in Arabidopsis thaliana · PMID 26946085 · 24 records
• Adenosine kinase mediates high affinity adenosine salvage in Trypanosoma brucei · PMID 18167353 · 16 records
• ADP-dependent 6-phosphofructokinase from Pyrococcus horikoshii OT3: structure determination and biochemical characterization of PH1645 · PMID 19553681 · 30 records
• ADP-Dependent Kinases From the Archaeal Order Methanosarcinales Adapt to Salt by a Non-canonical Evolutionarily Conserved Strategy · PMID 29997580 · 7 records
• ADP-dependent phosphofructokinases from the archaeal order Methanosarcinales display redundant glucokinase activity · PMID 28919057 · 8 records
• Adult and juvenile Fasciola cathepsin L proteases: different enzymes for different roles · PMID 21167899 · 31 records
• Aedes aegypti juvenile hormone acid methyl transferase, the ultimate enzyme in the biosynthetic pathway of juvenile hormone III, exhibits substrate control · PMID 24657668 · 8 records
• Aerobic Cytotoxicity of Aromatic N-Oxides: The Role of NAD(P)H:Quinone Oxidoreductase (NQO1) · PMID 33228195 · 28 records
• Agmatine coumaroyltransferase gene on the short arm of chromosome 2H is involved in hordatine biosynthesis in barley · PMID 42137025 · 8 records
• AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A · PMID 15078101 · 6 records
• AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A · PMID 15911373 · 7 records
• Akt-FoxO signaling drives co-adaptation to insecticide and host plant stresses in an herbivorous insect · PMID 39510378 · 11 records
• Alanine racemase free energy profiles from global analyses of progress curves · PMID 15198593 · 6 records
• Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions · PMID 12907737 · 32 records
• Alanine-scanning mutation approach for classification of the roles of conserved residues in the activity and substrate affinity of L-carnitine dehydrogenase · PMID 24101242 · 34 records
• Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity · PMID 21338592 · 1 record
• Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress · PMID 20207735 · 9 records
• Aldehyde dehydrogenase enzyme ALDH3H1 from Arabidopsis thaliana: Identification of amino acid residues critical for cofactor specificity · PMID 24463048 · 42 records
• Aldehyde dehydrogenase from adult human brain that dehydrogenates gamma-aminobutyraldehyde: purification, characterization, cloning and distribution · PMID 8645224 · 13 records
• Aldehyde dismutase activity of human liver alcohol dehydrogenase · PMID 8843167 · 3 records
• Aldo-keto Reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates · PMID 25577493 · 7 records
• Aldose reductase from human skeletal and heart muscle. Interconvertible forms related by thiol-disulfide exchange · PMID 2174432 · 7 records
• Aldoxime dehydratase co-existing with nitrile hydratase and amidase in the iron-type nitrile hydratase-producer Rhodococcus sp. N-771 · PMID 16233624 · 18 records
• Alkali and halide-resistant catalysis by the multipotent oxidase from Marinomonas mediterranea · PMID 15831249 · 7 records
• All four putative selectivity filter glycine residues in KtrB are essential for high affinity and selective K+ uptake by the KtrAB system from Vibrio alginolyticus · PMID 16210320 · 12 records
• Allene oxide synthase from Arabidopsis thaliana (CYP74A1) exhibits dual specificity that is regulated by monomer-micelle association · PMID 16831431 · 8 records
• Alliin lyase (Alliinase) from garlic (Allium sativum). Biochemical characterization and cDNA cloning · PMID 7979352 · 1 record
• Alliinase [S-alk(en)yl-L-cysteine sulfoxide lyase] from Allium tuberosum (Chinese chive)--purification, localization, cDNA cloning and heterologous functional expression · PMID 9799098 · 1 record
• Allosteric and catalytic functions of the PPi-binding motif in the ATP sulfurylase-GTPase system · PMID 14506286 · 18 records
• Allosteric communication in cysteinyl tRNA synthetase: a network of direct and indirect readout · PMID 21890630 · 11 records
• Allosteric ensembles elucidate mechanisms of inhibition in the human soluble epoxide hydrolase · PMID 42086723 · 8 records
• Allosteric inhibitor specificity of Thermotoga maritima 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase · PMID 23916814 · 8 records
• Allosteric kinetics of human carboxylesterase 1: species differences and interindividual variability · PMID 18383336 · 17 records
• Allosteric modulation of the Lon protease via ssDNA binding and local charge changes · PMID 39542252 · 12 records
• Allosteric monofunctional aspartate kinases from Arabidopsis · PMID 17140415 · 8 records
• Allosteric regulation of pyruvate kinase enables efficient and robust gluconeogenesis by preventing metabolic conflicts and carbon overflow · PMID 39873491 · 2 records
• Allosteric regulation of the human and mouse deoxyribonucleotide triphosphohydrolase sterile α-motif/histidine-aspartate domain-containing protein 1 (SAMHD1) · PMID 24828500 · 10 records
• Allostery and Evolution: A Molecular Journey Through the Structural and Dynamical Landscape of an Enzyme Super Family · PMID 39834309 · 8 records
• Allostery and Hysteresis Are Coupled in Human UDP-Glucose Dehydrogenase · PMID 27966912 · 7 records
• alpha-1,4-D-glucan phosphorylase of gram-positive Corynebacterium callunae: isolation, biochemical properties and molecular shape of the enzyme from solution X-ray scattering · PMID 9307027 · 16 records
• Alpha-isoenzyme of alcohol dehydrogenase from monkey liver. Cloning, expression, mechanism, coenzyme, and substrate specificity · PMID 1618764 · 56 records
• alpha-ketoglutaric semialdehyde dehydrogenase isozymes involved in metabolic pathways of D-glucarate, D-galactarate, and hydroxy-L-proline. Molecular and metabolic convergent evolution · PMID 17202142 · 20 records
• alpha-oxidation of fatty acids in higher plants. Identification of a pathogen-inducible oxygenase (piox) as an alpha-dioxygenase and biosynthesis of 2-hydroperoxylinolenic acid · PMID 10455113 · 8 records
• Alteration of leucine aminopeptidase from Streptomyces septatus TH-2 to phenylalanine aminopeptidase by site-directed mutagenesis · PMID 16269763 · 16 records
• Alteration of substrate specificity of cholesterol oxidase from Streptomyces sp. by site-directed mutagenesis · PMID 12082166 · 22 records
• Alteration of substrate specificity of fructosyl-amino acid oxidase from Fusarium oxysporum · PMID 17160532 · 22 records
• Alteration of the quaternary structure of human UDP-glucose dehydrogenase by a double mutation · PMID 17927902 · 4 records
• Altered substrate specificity of the gluco-oligosaccharide oxidase from Acremonium strictum · PMID 21455933 · 36 records
• Altering 2-Hydroxybiphenyl 3-Monooxygenase Regioselectivity by Protein Engineering for the Production of a New Antioxidant · PMID 29297973 · 12 records
• Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing · PMID 18028553 · 16 records
• Altering substrate specificity of Bacillus sp. SAM1606 alpha-glucosidase by comparative site-specific mutagenesis · PMID 8999834 · 42 records
• Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity · PMID 28396388 · 10 records
• Altering the nucleophile specificity of a protein-tyrosine phosphatase-catalyzed reaction. Probing the function of the invariant glutamine residues · PMID 9488671 · 63 records
• Altering the Substrate Specificity of Acetyl-CoA Synthetase by Rational Mutagenesis of the Carboxylate Binding Pocket · PMID 31117358 · 83 records
• Altering the substrate specificity of cephalosporin acylase by directed evolution of the Beta -subunit · PMID 12198140 · 12 records
• Alternate substrates of human glutaryl-CoA dehydrogenase: structure and reactivity of substrates, and identification of a novel 2-enoyl-CoA product · PMID 11802727 · 7 records
• Alternative Biotransformation of Retinal to Retinoic Acid or Retinol by an Aldehyde Dehydrogenase from Bacillus cereus · PMID 27107124 · 15 records
• Alternative sites for proton entry from the cytoplasm to the quinone binding site in Escherichia coli succinate dehydrogenase · PMID 18690748 · 57 records
• Alternative substrates for wild-type and L109A E. coli CTP synthases: kinetic evidence for a constricted ammonia tunnel · PMID 15511226 · 16 records
• Ambiguities in mapping the active site of a conformationally dynamic enzyme by directed mutation. Role of dynamics in structure-function correlations in Escherichia coli adenylosuccinate synthetase · PMID 9632649 · 28 records
• Amenability of the Gatekeeper Enzyme HphA to Engineering in the Homologation Pathway of l‑Phenylalanine and l‑Tyrosine through Homology-Based Site-Directed Mutagenesis · PMID 41799147 · 12 records
• Amine N-methyltransferases from rabbit liver · PMID 3949799 · 14 records
• Amine oxidases from Aspergillus niger: identification of a novel flavin-dependent enzyme · PMID 7727530 · 24 records
• Amino acid discrimination by a highly differentiated metal center of an aminoacyl-tRNA synthetase · PMID 12974627 · 41 records
• Amino acid residues 62 and 193 play the key role in regulating the synergism of substrate binding in oyster arginine kinase · PMID 15757662 · 14 records
• Amino acid residues involved in substrate binding and catalysis in an insect digestive beta-glycosidase · PMID 11342030 · 9 records
• Amino acid residues involved in substrate recognition of the Escherichia coli Orf135 protein · PMID 15823026 · 12 records
• Amino acid sequence determinants of extended spectrum cephalosporin hydrolysis by the class C P99 beta-lactamase · PMID 11591698 · 10 records
• Amino Acid Variants at the P94 Position in Staphylococcus aureus Class a Sortase Modulate Substrate Binding and Enzyme Activity · PMID 41926714 · 5 records
• Amino acids in transmembrane helix 1 confer major functional differences between human and mouse orthologs of the polyspecific membrane transporter OCT1 · PMID 35469921 · 48 records
• Amino acids involved in polyphosphate synthesis and its mobilization are distinct in polyphosphate kinase-1 from Mycobacterium tuberculosis · PMID 22110640 · 14 records
• Amino-acid substitutions at the domain interface affect substrate and allosteric inhibitor binding in α-isopropylmalate synthase from Mycobacterium tuberculosis · PMID 23500460 · 10 records
• Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides · PMID 22349737 · 18 records
• Aminoalcohol-Induced Activation of Organophosphorus Hydrolase (OPH) towards Diisopropylfluorophosphate (DFP) · PMID 28085964 · 60 records
• Aminopeptidase N1 (EtAPN1), an M1 metalloprotease of the apicomplexan parasite Eimeria tenella, participates in parasite development · PMID 24839124 · 8 records
• Ammonia channeling in bacterial glucosamine-6-phosphate synthase (Glms): molecular dynamics simulations and kinetic studies of protein mutants · PMID 17559838 · 18 records
• Amphioxus alcohol dehydrogenase is a class 3 form of single type and of structural conservation but with unique developmental expression · PMID 11054102 · 4 records
• Amylomaltase of Pyrobaculum aerophilum IM2 produces thermoreversible starch gels · PMID 16151092 · 5 records
• An (R)-Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines · PMID 27547270 · 11 records
• An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity · PMID 32729927 · 33 records
• An active site homology model of phenylalanine ammonia-lyase from Petroselinum crispum · PMID 12071972 · 12 records
• An active site tyrosine influences the ability of the dimethyl sulfoxide reductase family of molybdopterin enzymes to reduce S-oxides · PMID 11278798 · 28 records
• An active-site lysine in avian liver phosphoenolpyruvate carboxykinase · PMID 1909575 · 6 records
• An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability-activity trade-offs · PMID 18093993 · 26 records
• An additional glucose dehydrogenase from Sulfolobus solfataricus: fine-tuning of sugar degradation? · PMID 21265750 · 2 records
• An additional substrate binding site in a bacterial phenylalanine hydroxylase · PMID 23860686 · 5 records
• An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase · PMID 12105228 · 6 records
• An alcohol oxidase of Phanerochaete chrysosporium with a distinct glycerol oxidase activity · PMID 24910330 · 5 records
• An aldo-keto reductase with 2-keto-l-gulonate reductase activity functions in l-tartaric acid biosynthesis from vitamin C in Vitis vinifera · PMID 31488549 · 7 records
• An Alkyne-Containing Isoprenoid Analogue Based on a Farnesyl Diphosphate Scaffold Is a Biologically Functional Universal Probe for Proteomic Analysis · PMID 39652878 · 7 records
• An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme · PMID 15317584 · 7 records
• An alternative allosteric pathway in thermophilic methylglyoxal synthase · PMID 27608544 · 14 records
• An alternative allosteric regulation mechanism of an acidophilic l-lactate dehydrogenase from Enterococcus mundtii 15-1A · PMID 25379380 · 16 records
• An alternative mechanism for the methylation of phosphoethanolamine catalyzed by Plasmodium falciparum phosphoethanolamine methyltransferase · PMID 25288796 · 4 records
• An alternative pathway contributes to phenylalanine biosynthesis in plants via a cytosolic tyrosine:phenylpyruvate aminotransferase · PMID 24270997 · 8 records
• An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae · PMID 19196710 · 4 records
• An amino acid at position 142 in nitrilase from Rhodococcus rhodochrous ATCC 33278 determines the substrate specificity for aliphatic and aromatic nitriles · PMID 18412544 · 28 records
• An ancestral glutamine-dependent NAD(+) synthetase revealed by poor kinetic synergism · PMID 19647806 · 8 records
• An antenna-biased carboxylesterase is specifically active to plant volatiles in Spodoptera exigua · PMID 26267057 · 8 records
• An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases · PMID 12628650 · 8 records
• An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense · PMID 14617060 · 6 records
• An archaeal ADP-dependent serine kinase involved in cysteine biosynthesis and serine metabolism · PMID 27857065 · 2 records
• An aryl-alcohol oxidase of Pleurotus sapidus: heterologous expression, characterization, and application in a 2-enzyme system · PMID 27138199 · 3 records
• An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases · PMID 10587441 · 32 records
• An endoglucanase, EglA, from the hyperthermophilic archaeon Pyrococcus furiosus hydrolyzes beta-1,4 bonds in mixed-linkage (1-->3),(1-->4)-beta-D-glucans and cellulose · PMID 9864341 · 5 records
• An Engineered Alcohol Oxidase for the Oxidation of Primary Alcohols · PMID 30338899 · 14 records
• An Engineered Enzyme Catalyzing Tandem Reductive Aminations for Synthesizing Tertiary Amines · PMID 42454891 · 4 records
• An Engineered Tryptophan Synthase Opens New Enzymatic Pathways to β-Methyltryptophan and Derivatives · PMID 28005309 · 6 records
• An esterase from Escherichia coli with a sequence similarity to hormone-sensitive lipase · PMID 9576853 · 6 records
• An Examination by Site-Directed Mutagenesis of Putative Key Residues in the Determination of Coenzyme Specificity in Clostridial NAD-Dependent Glutamate Dehydrogenase · PMID 21876794 · 36 records
• An FMN hydrolase is fused to a riboflavin kinase homolog in plants · PMID 16183635 · 7 records
• An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis · PMID 27849620 · 6 records
• An important lysine residue in copper/quinone-containing amine oxidases · PMID 17433047 · 18 records
• An improved variant of tobacco etch virus (TEV) protease that does not need reducing agents · PMID 39969093 · 6 records
• An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11 · PMID 10050318 · 13 records
• An indoleacetate-CoA ligase and a phenylsuccinyl-CoA transferase involved in anaerobic metabolism of auxin · PMID 27102732 · 14 records
• An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target… · PMID 17950253 · 6 records
• An integrated genomic, proteomic and biochemical analysis of (+)-3-carene biosynthesis in Sitka spruce (Picea sitchensis) genotypes that are resistant or susceptible to white pine weevil · PMID 21323772 · 5 records
• An integrated study of threonine-pathway enzyme kinetics in Escherichia coli · PMID 11368768 · 17 records
• An LL-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants · PMID 16361515 · 4 records
• An NADPH:FAD oxidoreductase from the valanimycin producer, Streptomyces viridifaciens. Cloning, analysis, and overexpression · PMID 9287340 · 5 records
• An O-methyltransferase modifies accumulation of methylated anthocyanins in seedlings of tomato · PMID 25227758 · 7 records
• An omega-class glutathione S-transferase in the brown planthopper Nilaparvata lugens exhibits glutathione transferase and dehydroascorbate reductase activities · PMID 31328816 · 12 records
• An ornithine ω-aminotransferase required for growth in the absence of exogenous proline in the archaeon Thermococcus kodakarensis · PMID 29352105 · 4 records
• An overview of the kinetic parameters of class B beta-lactamases · PMID 8471035 · 43 records
• An Oxidative Pathway for Microbial Utilization of Methylphosphonic Acid as a Phosphate Source · PMID 30810303 · 5 records
• An S752D activation loop mutation dynamically primes Muscle-Specific Kinase for activation · PMID 42240394 · 7 records
• An uncharacterized member of the ribokinase family in Thermococcus kodakarensis exhibits myo-inositol kinase activity · PMID 23737529 · 9 records
• An unexpected alternative viologen electron mediator site in tungsten-containing formate dehydrogenase · PMID 42206755 · 9 records
• An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme · PMID 29523689 · 7 records
• An unprecedented NADPH domain conformation in lysine monooxygenase NbtG provides insights into uncoupling of oxygen consumption from substrate hydroxylation · PMID 25802330 · 20 records
• An unusual metal-bound 4-fluorothreonine transaldolase from Streptomyces sp. MA37 catalyses promiscuous transaldol reactions · PMID 32140842 · 8 records
• An unusual oxygen-sensitive, iron- and zinc-containing alcohol dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosus · PMID 9973342 · 9 records
• An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway · PMID 14532271 · 26 records
• Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase · PMID 26803203 · 17 records
• Analysis of a substrate specificity switch residue of cephalosporin acylase · PMID 14680829 · 38 records
• Analysis of Agaricus meleagris pyranose dehydrogenase N-glycosylation sites and performance of partially non-glycosylated enzymes · PMID 28193332 · 44 records
• Analysis of amino acid residues involved in catalysis of polyethylene glycol dehydrogenase from Sphingopyxis terrae, using three-dimensional molecular modeling-based kinetic characterization of… · PMID 16751555 · 34 records
• Analysis of catalytic properties of tripeptidyl peptidase I (TTP-I), a serine carboxyl lysosomal protease, and its detection in tissue extracts using selective FRET peptide substrate · PMID 26775801 · 8 records
• Analysis of Fasciola cathepsin L5 by S2 subsite substitutions and determination of the P1-P4 specificity reveals an unusual preference · PMID 22285967 · 12 records
• Analysis of flavin oxidation and electron-transfer inhibition in Plasmodium falciparum dihydroorotate dehydrogenase · PMID 18225919 · 37 records
• Analysis of the Atypical Temperature Dependence and Conformational Changes During Turnover of a Lactobacillus Chlorogenic Acid Esterase · PMID 42531162 · 6 records
• Analysis of the catalytic and binding residues of the diadenosine tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans by site-directed mutagenesis · PMID 12475970 · 17 records
• Analysis of the catalytic mechanism of a fungal lipase using computer-aided design and structural mutants · PMID 8862551 · 8 records
• Analysis of the enzymatic formation of citral in the glands of sweet basil · PMID 16150417 · 5 records
• Analysis of the enzymatic properties of a broad family of alanine aminotransferases · PMID 23408955 · 40 records
• Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis · PMID 12725860 · 36 records
• Analysis of the kinetic and redox properties of the NADH peroxidase R303M mutant: correlation with the crystal structure · PMID 10956025 · 8 records
• Analysis of the kinetic mechanism of enterococcal NADH peroxidase reveals catalytic roles for NADH complexes with both oxidized and two-electron-reduced enzyme forms · PMID 7578008 · 13 records
• Analysis of the kinetic mechanism of the bovine liver mitochondrial dihydroorotate dehydrogenase · PMID 2540819 · 6 records
• Analysis of the kinetics of prothrombin activation and evidence that two equilibrating forms of prothrombinase are involved in the process · PMID 12496269 · 13 records
• Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs · PMID 16940157 · 21 records
• Analysis of the putative substrate binding region of hyperthermophilic endoglucanase from Pyrococcus horikoshii · PMID 17928686 · 11 records
• Analysis of the role of the active site residue Arg98 in the flavoprotein tryptophan 2-monooxygenase, a member of the L-amino oxidase family · PMID 14636049 · 4 records
• Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis · PMID 19154134 · 11 records
• Analysis of the substrate specificity loop of the HAD superfamily cap domain · PMID 15005616 · 13 records
• Analysis of the substrate specificity of human sulfotransferases SULT1A1 and SULT1A3: site-directed mutagenesis and kinetic studies · PMID 10441143 · 38 records
• Analysis of tissue plasminogen activator specificity using peptidyl fluorogenic substrates · PMID 9047311 · 76 records
• Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1 · PMID 26077812 · 7 records
• Analyzing the catalytic role of Asp97 in the methionine aminopeptidase from Escherichia coli · PMID 19019076 · 7 records
• Ancestral sequence reconstruction produces thermally stable enzymes with mesophilic enzyme-like catalytic properties · PMID 32968141 · 26 records
• Anchoring mechanism-inspired discovery of a bacterial P450 gene conferring resistance to auxin herbicides · PMID 42642398 · 8 records
• Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana · PMID 14725861 · 8 records
• Anthranilate-activating modules from fungal nonribosomal peptide assembly lines · PMID 20225828 · 8 records
• Antibacterial activity of enmetazobactam against Acinetobacter spp.: a molecular dissection of mechanism of action and resistance determinants · PMID 41427713 · 2 records
• Antibiotic-Adjuvants Abolish Resistance Conferred by the Staphylococcus aureus Erythromycin Resistance Methyltransferase in an Escherichia coli Model · PMID 41369274 · 6 records
• Anticancer, antioxidant and antibacterial potential of L-Glutaminase (Streptomyces roseolus strain ZKB1) capped silver and zinc oxide nanoparticles and its molecular characterization · PMID 40121594 · 2 records
• Antioxidative function and substrate specificity of NAD(P)H-dependent alkenal/one oxidoreductase. A new role for leukotriene B4 12-hydroxydehydrogenase/15-oxoprostaglandin 13-reductase · PMID 11524419 · 20 records
• Antiplasmodial activity of quinones: roles of aziridinyl substituents and the inhibition of Plasmodium falciparum glutathione reductase · PMID 19919822 · 48 records
• ApbA, the ketopantoate reductase enzyme of Salmonella typhimurium is required for the synthesis of thiamine via the alternative pyrimidine biosynthetic pathway · PMID 9488683 · 2 records
• APHO1 from the yeast Arxula adeninivorans encodes an acid phosphatase of broad substrate specificity · PMID 17016743 · 30 records
• Application of the YebF secretion pathway in Escherichia coli for rapid, on-plate screening of PETase libraries for improved activity · PMID 42206195 · 6 records
• Applying the Sabatier Principle to Decipher the Surface-Structure-Dependent Catalysis of Different Starch Granules by Pullulanase · PMID 39886568 · 12 records
• Approaches to the simultaneous inactivation of metallo- and serine-beta-lactamases · PMID 19243936 · 24 records
• Aprataxin forms a discrete branch in the HIT (histidine triad) superfamily of proteins with both DNA/RNA binding and nucleotide hydrolase activities · PMID 16547001 · 4 records
• Aqueous-Phase Polycondensation of Hydroxy Fatty Acids via a Whole-Cell CoA Activation-Acyltransferase Cascade · PMID 41755814 · 2 records
• Arabidopsis CYP735A1 and CYP735A2 encode cytokinin hydroxylases that catalyze the biosynthesis of trans-Zeatin · PMID 15280363 · 6 records
• Arabidopsis glyoxalase II contains a zinc/iron binuclear metal center that is essential for substrate binding and catalysis · PMID 11085979 · 7 records
• Arabidopsis phosphoglycerate dehydrogenase1 of the phosphoserine pathway is essential for development and required for ammonium assimilation and tryptophan biosynthesis · PMID 24368794 · 12 records
• Arabidopsis thaliana GH3.15 acyl acid amido synthetase has a highly specific substrate preference for the auxin precursor indole-3-butyric acid · PMID 29462792 · 31 records
• Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity · PMID 15180996 · 3 records
• Arabidopsis thaliana NADP-malic enzyme isoforms: high degree of identity but clearly distinct properties · PMID 18288573 · 23 records
• Arabidopsis VTC2 encodes a GDP-L-galactose phosphorylase, the last unknown enzyme in the Smirnoff-Wheeler pathway to ascorbic acid in plants · PMID 17462988 · 7 records
• Archaeal Mo-Containing Glyceraldehyde Oxidoreductase Isozymes Exhibit Diverse Substrate Specificities through Unique Subunit Assemblies · PMID 26808202 · 22 records
• Archaeal NSUN6 catalyzes m5C72 modification on a wide-range of specific tRNAs · PMID 30541086 · 31 records
• Arg-85 and Thr-430 in murine 5-aminolevulinate synthase coordinate acyl-CoA-binding and contribute to substrate specificity · PMID 19562746 · 38 records
• Arginine 165/arginine 277 pair in (S)-mandelate dehydrogenase from Pseudomonas putida: role in catalysis and substrate binding · PMID 12369819 · 10 records
• Arginine 177 is involved in Mn(II) binding by manganese peroxidase · PMID 10471300 · 9 records
• Arginine inhibits the arginine biosynthesis rate-limiting enzyme and leads to the accumulation of intracellular aspartate in Synechocystis sp. PCC 6803 · PMID 38478146 · 3 records
• Arginine-178 is an essential residue for ITPA function · PMID 37506994 · 5 records
• Arginines 65 and 310 in putidaredoxin reductase are critical for interaction with putidaredoxin · PMID 20524621 · 32 records
• Aristolochene synthase: mechanistic analysis of active site residues by site-directed mutagenesis · PMID 15186158 · 14 records
• Aristolochene synthase: purification, molecular cloning, high-level expression in Escherichia coli, and characterization of the Aspergillus terreus cyclase · PMID 10775423 · 3 records
• Aromatic aldehydes at the active site of aldehyde oxidoreductase from Desulfovibrio gigas: reactivity and molecular details of the enzyme-substrate and enzyme-product interaction · PMID 25261288 · 9 records
• Aromatic Residue F443 Modulates the Dimer Interface and Activity of Pseudomonas mandelii Glutathione Reductase · PMID 40060842 · 7 records
• Aromatic stacking interactions govern catalysis in aryl-alcohol oxidase · PMID 25639975 · 14 records
• Arresting the Catalytic Arginine in Chlorite Dismutases: Impact on Heme Coordination, Thermal Stability, and Catalysis · PMID 33586945 · 9 records
• Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty · PMID 11573087 · 4 records
• Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange · PMID 19286650 · 14 records
• Aryl sulfotransferase IV from rat liver · PMID 6946725 · 18 records
• Arylamine N-acetyltransferase responsible for acetylation of 2-aminophenols in Streptomyces griseus · PMID 17158669 · 9 records
• Arylamine N-acetyltransferases: characterization of the substrate specificities and molecular interactions of environmental arylamines with human NAT1 and NAT2 · PMID 17672512 · 30 records
• Ascertaining the biochemical function of an essential pectin methylesterase in the gut microbe Bacteroides thetaiotaomicron · PMID 33097594 · 12 records
• Asn-150 of Murine Erythroid 5-Aminolevulinate Synthase Modulates the Catalytic Balance between the Rates of the Reversible Reaction · PMID 26511319 · 16 records
• Asn249Tyr substitution at the coenzyme binding domain activates Sulfolobus solfataricus alcohol dehydrogenase and increases its thermal stability · PMID 10074357 · 16 records
• Asp-120 locates Zn2 for optimal metallo-beta-lactamase activity · PMID 17426028 · 20 records
• Asp79 makes a large, unfavorable contribution to the stability of RNase Sa · PMID 16288913 · 7 records
• Asparagine 229 in thymidylate synthase contributes to, but is not essential for, catalysis · PMID 8378336 · 44 records
• Asparagine362 is essential for zinc binding and catalysis in the peptidase reaction of Saccharomyces cerevisiae leukotriene A₄ hydrolase · PMID 20624488 · 32 records
• Asparaginyl-tRNA synthetase from the Escherichia coli temperature-sensitive strain HO202. A proline replacement in motif 2 is responsible for a large increase in Km for asparagine and ATP · PMID 1544480 · 12 records
• Asparatic acid 221 is critical in the calcium-induced modulation of the enzymatic activity of human aminopeptidase A · PMID 17932029 · 26 records
• Aspartate 458 of human glutathione synthetase is important for cooperativity and active site structure · PMID 21771585 · 12 records
• Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis · PMID 32327655 · 3 records
• Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643 · PMID 12496312 · 4 records
• Aspartic acid 214 in Citrobacter freundii tyrosine phenol-lyase ensures sufficient C--H-acidity of the external aldimine intermediate and proper orientation of the cofactor at the active site · PMID 16793353 · 17 records
• Aspartic acid 397 in subunit B of the Na+-pumping NADH:quinone oxidoreductase from Vibrio cholerae forms part of a sodium-binding site, is involved in cation selectivity, and affects cation-binding… · PMID 24030824 · 9 records
• Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization… · PMID 42045997 · 4 records
• Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target · PMID 32005728 · 3 records
• Aspergillus fumigatus SidA is a highly specific ornithine hydroxylase with bound flavin cofactor · PMID 20614882 · 8 records
• Assay of L-3-hydroxyacyl-coenzyme A dehydrogenase with substrates of different chain lengths · PMID 2817332 · 6 records
• Assembly and engineering of BioBricks to develop an efficient NADH regeneration system · PMID 39660873 · 8 records
• Assessing the roles of essential functional groups in the mechanism of homoserine succinyltransferase · PMID 17442255 · 28 records
• Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars · PMID 27402745 · 37 records
• Assignment of pterin deaminase activity to an enzyme of unknown function guided by homology modeling and docking · PMID 23256477 · 14 records
• Association between Archaeal prolyl- and leucyl-tRNA synthetases enhances tRNA(Pro) aminoacylation · PMID 15917221 · 10 records
• Association of both enoyl coenzyme A hydratase and 3-hydroxyacyl coenzyme A epimerase with an active site in the amino-terminal domain of the multifunctional fatty acid oxidation protein from… · PMID 8454629 · 10 records
• Astacin · PMID 7674929 · 1 record
• Atomic resolution structures of R-specific alcohol dehydrogenase from Lactobacillus brevis provide the structural bases of its substrate and cosubstrate specificity · PMID 15896805 · 10 records
• ATP binding site in the plant ADP-glucose pyrophosphorylase large subunit · PMID 17137579 · 50 records
• ATP sulfurylase from higher plants: kinetic and structural characterization of the chloroplast and cytosol enzymes from spinach leaf · PMID 8274013 · 17 records
• ATP synthesis of Enterococcus hirae V-ATPase driven by sodium motive force · PMID 40118453 · 2 records
• ATP- and Polyphosphate-Dependent Glucokinases from Aerobic Methanotrophs · PMID 30769875 · 4 records
• ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3) · PMID 10644759 · 4 records
• Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity · PMID 18758447 · 4 records
• Atypical transient state kinetics of recombinant human dihydrofolate reductase produced by hysteretic behavior. Comparison with dihydrofolate reductases from other sources · PMID 2492521 · 9 records
• Augmented hydrolysis of diisopropyl fluorophosphate in engineered mutants of phosphotriesterase · PMID 9325279 · 70 records
• Augmented intrinsic activity of Factor VIIa by replacement of residues 305, 314, 337 and 374: evidence of two unique mutational mechanisms of activity enhancement · PMID 14686879 · 12 records
• Automated Engineering Protein Dynamics via Loop Grafting: Improving Renilla Luciferase Catalysis · PMID 40013243 · 3 records
• Autoprocessing and peptide substrates for human herpesvirus 6 proteinase · PMID 9756878 · 15 records
• Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid binding · PMID 15882147 · 10 records
• Axial bonds at the T1 Cu site of Thermus thermophilus SG0.5JP17-16 laccase influence enzymatic properties · PMID 30964606 · 6 records
• B-factor-saturation mutagenesis as a strategy to increase the thermostability of α-L-rhamnosidase from Aspergillus terreus · PMID 29605638 · 3 records
• Bacillus licheniformis trehalose-6-phosphate hydrolase structures suggest keys to substrate specificity · PMID 26894535 · 10 records
• Bacillus subtilis chorismate mutase is partially diffusion-controlled · PMID 10103029 · 11 records
• Bacillus subtilis encodes three N-acetylcysteine deacetylase enzymes that can catalyze the final step in S-(2-succino)cysteine breakdown · PMID 41260340 · 3 records
• Bacillus subtilis MutL samples multiple conformations during nucleotide binding and hydrolysis · PMID 41478286 · 1 record
• Bacterial 2,4-dioxygenases: new members of the alpha/beta hydrolase-fold superfamily of enzymes functionally related to serine hydrolases · PMID 10482514 · 5 records
• Bacterial acyl-CoA mutase specifically catalyzes coenzyme B12-dependent isomerization of 2-hydroxyisobutyryl-CoA and (S)-3-hydroxybutyryl-CoA · PMID 22433853 · 7 records
• Bacterial Anabaena variabilis phenylalanine ammonia lyase: a biocatalyst with broad substrate specificity · PMID 25037641 · 32 records
• Bacterial and eukaryotic phenylalanyl-tRNA synthetases catalyze misaminoacylation of tRNA(Phe) with 3,4-dihydroxy-L-phenylalanine · PMID 22035791 · 8 records
• Bacterial Avenalumic Acid Biosynthesis Includes Substitution of an Aromatic Amino Group for Hydride by Nitrous Acid Dependent Diazotization · PMID 36115045 · 5 records
• Bacterial beta-peptidyl aminopeptidases with unique substrate specificities for beta-oligopeptides and mixed beta,alpha-oligopeptides · PMID 17064315 · 8 records
• Bacterial citrate synthases: purification, molecular weight and kinetic mechanism · PMID 4211224 · 14 records
• Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo · PMID 19487291 · 8 records
• Bacterial expression and characterization of catalytic loop mutants of SRC protein tyrosine kinase · PMID 17144667 · 14 records
• Bacterial Sugar 3,4-Ketoisomerases: Structural Insight into Product Stereochemistry · PMID 26125548 · 11 records
• Bacterial β-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2) · PMID 27115290 · 9 records
• Banana aroma is a result of acetohydroxyacid synthase and isopropylmalate synthase alternative isoforms that bypass feedback inhibition · PMID 41802060 · 9 records
• Barley xyloglucan xyloglucosyl transferases bind xyloglucan-derived oligosaccharides in their acceptor-binding regions in multiple conformational states · PMID 20117073 · 9 records
• Basic residues play key roles in catalysis and NADP(+)-specificity in maize (Zea mays L.) photosynthetic NADP(+)-dependent malic enzyme · PMID 15245332 · 5 records
• Basic-patch mutations in bacteriophage T4 Rad50 uncouple ATPase activation from processive nuclease activity · PMID 42417150 · 18 records
• BEL-1, a novel clavulanic acid-inhibited extended-spectrum beta-lactamase, and the class 1 integron In120 in Pseudomonas aeruginosa · PMID 16127048 · 12 records
• Benzyl alcohol biosynthesis and its subcellular compartmentalization enable scent formation and salicylic acid production · PMID 42443198 · 14 records
• Beta sheet 2-alpha helix C loop of cytochrome P450 reductase serves as a docking site for redox partners · PMID 20152939 · 30 records
• Beta-cyanoalanine synthase and cysteine synthase from potato: molecular cloning, biochemical characterization, and spatial and hormonal regulation · PMID 11575729 · 14 records
• beta-D-Xylosidase from Selenomonas ruminantium: role of glutamate 186 in catalysis revealed by site-directed mutagenesis, alternate substrates, and active-site inhibitor · PMID 20127424 · 14 records
• Beta-glucosidase, exo-beta-glucanase and pyridoxine transglucosylase activities of rice BGlu1 · PMID 14692878 · 26 records
• Beta-ketophosphonates as beta-lactamase inhibitors: Intramolecular cooperativity between the hydrophobic subsites of a class D beta-lactamase · PMID 18572409 · 5 records
• Beta-lactamases (Actinomycetes species) · PMID 1134377 · 18 records
• Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase · PMID 18230605 · 3 records
• Bidirectional catalysis by copper-containing nitrite reductase · PMID 15301545 · 14 records
• Bifunctional ADP-dependent phosphofructokinase/glucokinase activity in the order Methanococcales--biochemical characterization of the mesophilic enzyme from Methanococcus maripaludis · PMID 24860874 · 8 records
• Bifunctional catalysis by CDP-ribitol synthase: convergent recruitment of reductase and cytidylyltransferase activities in Haemophilus influenzae and Staphylococcus aureus · PMID 15362865 · 8 records
• Bifunctional cytosolic UDP-glucose 4-epimerases catalyse the interconversion between UDP-D-xylose and UDP-L-arabinose in plants · PMID 19754426 · 14 records
• Bifunctional homodimeric triokinase/FMN cyclase: contribution of protein domains to the activities of the human enzyme and molecular dynamics simulation of domain movements · PMID 24569995 · 31 records
• Bifunctional isocitrate-homoisocitrate dehydrogenase: a missing link in the evolution of beta-decarboxylating dehydrogenase · PMID 15845397 · 3 records
• Bifunctional Malic/Malolactic Enzyme Provides a Novel Mechanism for NADPH-Balancing in Bacillus subtilis · PMID 33824210 · 4 records
• Bifunctional phosphoglucose/phosphomannose isomerases from the Archaea Aeropyrum pernix and Thermoplasma acidophilum constitute a novel enzyme family within the phosphoglucose isomerase superfamily · PMID 14551194 · 7 records
• Binding energy and specificity in the catalytic mechanism of yeast aldose reductases · PMID 10548539 · 60 records
• Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi · PMID 26999093 · 10 records
• Binding mode between peptidyl-tRNA hydrolase and the peptidyl-A76 moiety of the substrate · PMID 40049414 · 5 records
• Binding of 14-3-3 stabilises recombinant AMPKγ2-containing complexes · PMID 41873906 · 3 records
• Binding of ATP at the active site of human pancreatic glucokinase--nucleotide-induced conformational changes with possible implications for its kinetic cooperativity · PMID 21569204 · 7 records
• Binuclear metal centers in plant purple acid phosphatases: Fe-Mn in sweet potato and Fe-Zn in soybean · PMID 10510276 · 22 records
• Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase from Nicotiana tabacum · PMID 27547488 · 7 records
• Biocatalytic Indigo Synthesis From L-Tryptophan Using a Three-Step Cascade Without Cofactor Regeneration · PMID 42011133 · 2 records
• Biocatalytic sulfation of aromatic and aliphatic alcohols catalyzed by arylsulfate sulfotransferases · PMID 39560778 · 14 records
• Biocatalytic versatility of engineered and wild-type tyrosinase from R. solanacearum for the synthesis of 4-halocatechols · PMID 29691629 · 16 records
• Biochemical analysis and structure determination of bacterial acetyltransferases responsible for the biosynthesis of UDP-N,N'-diacetylbacillosamine · PMID 24064219 · 24 records
• Biochemical analysis and the preliminary crystallographic characterization of D-tagatose 3-epimerase from Rhodobacter sphaeroides · PMID 29121933 · 8 records
• Biochemical analysis of a beta-D-xylosidase and a bifunctional xylanase-ferulic acid esterase from a xylanolytic gene cluster in Prevotella ruminicola 23 · PMID 19304844 · 7 records
• Biochemical analysis of the 20 S proteasome of Trypanosoma brucei · PMID 12600991 · 8 records
• Biochemical analysis of Thermotoga maritima GH36 alpha-galactosidase (TmGalA) confirms the mechanistic commonality of clan GH-D glycoside hydrolases · PMID 17323919 · 26 records
• Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP) · PMID 33536500 · 6 records
• Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase · PMID 27226387 · 5 records
• Biochemical and Computational Characterization of Haloalkane Dehalogenase Variants Designed by Generative AI: Accelerating the S_N2 Step · PMID 39792627 · 5 records
• Biochemical and Computational Insights on a Novel Acid-Resistant and Thermal-Stable Glucose 1-Dehydrogenase · PMID 28587256 · 3 records
• Biochemical and crystallographic analysis of substrate binding and conformational changes in acetyl-CoA synthetase · PMID 17497934 · 27 records
• Biochemical and crystallographic characterization of ferredoxin-NADP(+) reductase from nonphotosynthetic tissues · PMID 11724563 · 8 records
• Biochemical and Expression Analyses of the Rice Cinnamoyl-CoA Reductase Gene Family · PMID 29312373 · 9 records
• Biochemical and genetic analysis of a cutinase-type polyesterase from a thermophilic Thermobifida alba AHK119 · PMID 22183084 · 4 records
• Biochemical and genetic analysis of methylenetetrahydrofolate reductase in Leishmania metabolism and virulence · PMID 17032644 · 5 records
• Biochemical and genetic characterization of carbapenem-hydrolyzing β-lactamase OXA-229 from Acinetobacter bereziniae · PMID 22508298 · 8 records
• Biochemical and kinetic analysis of the GH3 family beta-xylosidase from Aspergillus awamori X-100 · PMID 17145041 · 16 records
• Biochemical and kinetic characterization of the recombinant ADP-forming acetyl coenzyme A synthetase from the amitochondriate protozoan Entamoeba histolytica · PMID 25303954 · 17 records
• Biochemical and mass spectrometric characterization of soluble ecto-5'-nucleotidase from bull seminal plasma · PMID 12608891 · 16 records
• Biochemical and Mechanistic Insights into O₂ Scavenging and Stability of the Soluble Hydrogenase from Hydrogenophaga pseudoflava · PMID 41552538 · 4 records
• Biochemical and molecular characterization of a ring fission dioxygenase with the ability to oxidize (substituted) salicylate(s) from Pseudaminobacter salicylatoxidans · PMID 15220336 · 18 records
• Biochemical and Molecular Characterization of Glycerol Dehydrogenas from Klebsiella pneumoniae · PMID 31635443 · 4 records
• Biochemical and molecular characterization of phenylacetate-coenzyme A ligase, an enzyme catalyzing the first step in aerobic metabolism of phenylacetic acid in Azoarcus evansii · PMID 10629172 · 3 records
• Biochemical and molecular characterization of the isocitrate dehydrogenase with dual coenzyme specificity from the obligate methylotroph Methylobacillus Flagellatus · PMID 28423051 · 4 records
• Biochemical and molecular characterization of the NAD(+)-dependent isocitrate dehydrogenase from the chemolithotroph Acidithiobacillus thiooxidans · PMID 12204383 · 3 records
• Biochemical and molecular characterization of the oxidative branch of glycerol utilization by Citrobacter freundii · PMID 7635824 · 4 records
• Biochemical and molecular characterization of three new variants of AmpC beta-lactamases from Morganella morganii · PMID 16495258 · 19 records
• Biochemical and molecular genetic characterisation of a novel laccase produced by the aquatic ascomycete Phoma sp. UHH 5-1-03 · PMID 19455326 · 5 records
• Biochemical and molecular modeling studies of the O-methylation of various endogenous and exogenous catechol substrates catalyzed by recombinant human soluble and membrane-bound… · PMID 17880176 · 38 records
• Biochemical and mutational analyses of a Trametes pyranose oxidase and comparison of its mutants in breadmaking · PMID 29536215 · 5 records
• Biochemical and mutational analysis of a novel nicotinamidase from Oceanobacillus iheyensis HTE831 · PMID 23451075 · 26 records
• Biochemical and phylogenetic characterization of a novel diaminopimelate biosynthesis pathway in prokaryotes identifies a diverged form of LL-diaminopimelate aminotransferase · PMID 18310350 · 16 records
• Biochemical and physiological analyses of NADPH-dependent thioredoxin reductase isozymes in Euglena gracilis · PMID 26025518 · 7 records
• Biochemical and physiological characterization of Aedes aegypti midgut chymotrypsin · PMID 40113878 · 61 records
• Biochemical and spectroscopic characterization of Escherichia coli aconitases (AcnA and AcnB) · PMID 10585860 · 24 records
• Biochemical and structural analyses of metallo-β-lactamase VIM-28: impact of substitutions at residues 224 and 228 on substrate profile, stability, and zinc affinity · PMID 41660846 · 96 records
• Biochemical and Structural Characterisation of a Bacterial Lactoperoxidase · PMID 39570012 · 7 records
• Biochemical and structural characterisation of cutinase mutants in the presence of the anionic surfactant AOT · PMID 18501723 · 20 records
• Biochemical and structural characterization of a short-chain dehydrogenase/reductase of Thermus thermophilus HB8: a hyperthermostable aldose-1-dehydrogenase with broad substrate specificity · PMID 18926808 · 28 records
• Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase · PMID 25542170 · 6 records
• Biochemical and Structural Characterization of l-2-Keto-3-deoxyarabinonate Dehydratase: A Unique Catalytic Mechanism in the Class I Aldolase Protein Superfamily · PMID 32697085 · 27 records
• Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV · PMID 20977429 · 12 records
• Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2 · PMID 22342964 · 4 records
• Biochemical and structural characterization of polyphosphate kinase 2 from the intracellular pathogen Francisella tularensis · PMID 26582818 · 4 records
• Biochemical and structural characterization of quinoprotein aldose sugar dehydrogenase from Thermus thermophilus HJ6: Mutational analysis of Tyr156 in the substrate-binding site · PMID 27592307 · 41 records
• Biochemical and structural characterization of Salmonella typhimurium glyoxalase II: new insights into metal ion selectivity · PMID 17764159 · 4 records
• Biochemical and structural characterization of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Pyrococcus horikoshii · PMID 18405676 · 12 records
• Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4 · PMID 21149620 · 9 records
• Biochemical and structural characterization of the trans-enoyl-CoA reductase from Treponema denticola · PMID 22906002 · 20 records
• Biochemical and structural characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid · PMID 21241053 · 12 records
• Biochemical and Structural Characterization of XoxG and XoxJ and Their Roles in Lanthanide-Dependent Methanol Dehydrogenase Activity · PMID 31017712 · 6 records
• Biochemical and structural features of diverse bacterial glucuronoyl esterases facilitating recalcitrant biomass conversion · PMID 30083226 · 100 records
• Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase · PMID 15328606 · 44 records
• Biochemical and structural studies of conserved Maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides · PMID 24210219 · 42 records
• Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase · PMID 22128181 · 9 records
• Biochemical and thermodynamic characterization of mutated β1,4-galactosyltransferase 7 involved in the progeroid form of the Ehlers-Danlos syndrome · PMID 20809901 · 22 records
• Biochemical and X-ray crystallographic studies on shikimate kinase: the important structural role of the P-loop lysine · PMID 11369852 · 6 records
• Biochemical characterisation of aconitase from Corynebacterium glutamicum · PMID 20647021 · 3 records
• Biochemical characterisation of the CTX-M-14 beta-lactamase · PMID 17207608 · 16 records
• Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica · PMID 16938293 · 3 records
• Biochemical characteristics of maltose phosphorylase MalE from Bacillus sp. AHU2001 and chemoenzymatic synthesis of oligosaccharides by the enzyme · PMID 31262243 · 18 records
• Biochemical characteristics of the novel haloalkane dehalogenase DatA, isolated from the plant pathogen Agrobacterium tumefaciens C58 · PMID 21193677 · 5 records
• Biochemical Characterization and Active-Site Analysis of N-Acetylornithine Aminotransferase from Crocosphaera subtropica ATCC 51142 · PMID 42514279 · 10 records
• Biochemical Characterization and Complete Conversion of Coenzyme Specificity of Isocitrate Dehydrogenase from Bifidobacterium longum · PMID 26927087 · 10 records
• Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism · PMID 10231530 · 4 records
• Biochemical characterization and discovery of inhibitors for PfSir2A: new tricks for an old enzyme · PMID 39897407 · 12 records
• Biochemical characterization and essentiality of Plasmodium fumarate hydratase · PMID 29449371 · 3 records
• Biochemical characterization and FAD-binding analysis of oleate hydratase from Macrococcus caseolyticus · PMID 22203098 · 5 records
• Biochemical characterization and identification of the catalytic residues of a family 43 beta-D-xylosidase from Geobacillus stearothermophilus T-6 · PMID 15628881 · 16 records
• Biochemical characterization and kinetic properties of alanine aminotransferase homologues partially purified from wheat (Triticum aestivum L.) · PMID 22863564 · 20 records
• Biochemical characterization and mechanism of action of a thermostable beta-glucosidase purified from Thermoascus aurantiacus · PMID 11115405 · 7 records
• Biochemical characterization and molecular cloning of a plasminogen activator proteinase (LV-PA) from bushmaster snake venom · PMID 17034951 · 4 records
• Biochemical characterization and mutational analysis of alanine racemase from Clostridium perfringens · PMID 30826314 · 18 records
• Biochemical characterization and mutational improvement of a thermophilic esterase from Sulfolobus solfataricus P2 · PMID 20386955 · 4 records
• Biochemical characterization and physiological properties of Escherichia coli UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase · PMID 17384195 · 8 records
• Biochemical characterization and structural analysis of a highly proficient cocaine esterase · PMID 12369817 · 10 records
• Biochemical characterization and synthetic application of aromatic L-amino acid decarboxylase from Bacillus atrophaeus · PMID 33713143 · 5 records
• Biochemical characterization of a beta-galactosidase with a low temperature optimum obtained from an Antarctic arthrobacter isolate · PMID 12949099 · 9 records
• Biochemical characterization of a carboxylesterase from the archaeon Pyrobaculum sp. 1860 and a rational explanation of its substrate specificity and thermostability · PMID 25250909 · 4 records
• Biochemical characterization of a dihydroneopterin aldolase used for methanopterin biosynthesis in methanogens · PMID 24982305 · 7 records
• Biochemical Characterization of a Flavonoid O-methyltransferase from Perilla Leaves and Its Application in 7-Methoxyflavonoid Production · PMID 32998370 · 6 records
• Biochemical characterization of a haloalkane dehalogenase DadB from Alcanivorax dieselolei B-5 · PMID 24586552 · 6 records
• Biochemical characterization of a new nicotinamidase from an unclassified bacterium thriving in a geothermal water stream microbial mat community · PMID 28750065 · 27 records
• Biochemical characterization of a novel hypoxanthine/xanthine dNTP pyrophosphatase from Methanococcus jannaschii · PMID 11452035 · 23 records
• Biochemical characterization of a recombinant short-chain NAD(H)-dependent dehydrogenase/reductase from Sulfolobus acidocaldarius · PMID 20049620 · 21 records
• Biochemical characterization of a thermophilic cellobiose 2-epimerase from a thermohalophilic bacterium, Rhodothermus marinus JCM9785 · PMID 22056431 · 2 records
• Biochemical characterization of an L-tryptophan dehydrogenase from the photoautotrophic cyanobacterium Nostoc punctiforme · PMID 24835098 · 7 records
• Biochemical characterization of an L-Xylulose reductase from Neurospora crassa · PMID 17261518 · 4 records
• Biochemical characterization of Aspergillus awamori exoinulinase: substrate binding characteristics and regioselectivity of hydrolysis · PMID 12922166 · 11 records
• Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase · PMID 30547035 · 8 records
• Biochemical characterization of Aspergillus oryzae native tannase and the recombinant enzyme expressed in Pichia pastoris · PMID 24856589 · 12 records
• Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes · PMID 18703501 · 8 records
• Biochemical Characterization of Disease-Associated Variants of Human Ornithine Transcarbamylase · PMID 40059726 · 28 records
• Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7 · PMID 17905981 · 4 records
• Biochemical characterization of glutaredoxins from Chlamydomonas reinhardtii: kinetics and specificity in deglutathionylation reactions · PMID 20406640 · 6 records
• Biochemical characterization of Helicobacter pylori α1-3-fucosyltransferase and its application in the synthesis of fucosylated human milk oligosaccharides · PMID 31132553 · 4 records
• Biochemical characterization of human cathepsin X revealed that the enzyme is an exopeptidase, acting as carboxymonopeptidase or carboxydipeptidase · PMID 10951198 · 19 records
• Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins · PMID 16337200 · 6 records
• Biochemical Characterization of Hypothetical Proteins from Helicobacter pylori · PMID 23825549 · 18 records
• Biochemical characterization of indole prenyltransferases: filling the last gap of prenylation positions by a 5-dimethylallyltryptophan synthase from Aspergillus clavatus · PMID 22123822 · 13 records
• Biochemical characterization of L-asparaginase isoforms from Rhizobium etli-the boosting effect of zinc · PMID 38456185 · 17 records
• Biochemical characterization of laboratory mutants of extended-spectrum beta-lactamase TEM-60 · PMID 15328132 · 16 records
• Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain · PMID 18362187 · 24 records
• Biochemical characterization of mouse d-aspartate oxidase · PMID 32553892 · 6 records
• Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability · PMID 25324420 · 56 records
• Biochemical characterization of pantoate kinase, a novel enzyme necessary for coenzyme A biosynthesis in the Archaea · PMID 22865846 · 10 records
• Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans · PMID 16774642 · 6 records
• Biochemical characterization of recombinant Enterovirus 71 3C protease with fluorogenic model peptide substrates and development of a biochemical assay · PMID 25421478 · 10 records
• Biochemical characterization of SHV-55, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae · PMID 18316524 · 10 records
• Biochemical characterization of the 2-ketoacid reductases encoded by ycdW and yiaE genes in Escherichia coli · PMID 11237876 · 5 records
• Biochemical characterization of the carbapenem-hydrolyzing beta-lactamase AsbM1 from Aeromonas sobria AER 14M: a member of a novel subgroup of metallo-beta-lactamases · PMID 8998985 · 7 records
• Biochemical characterization of the class B acid phosphatase (AphA) of Escherichia coli MG1655 · PMID 16297670 · 20 records
• Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production · PMID 16896603 · 4 records
• Biochemical Characterization of the Lysine Acetylation of Tyrosyl-tRNA Synthetase in Escherichia coli · PMID 28741290 · 14 records
• Biochemical characterization of the Nocardia lactamdurans ACV synthetase · PMID 32275728 · 4 records
• Biochemical characterization of the phosphatase domain of the tumor suppressor PH domain leucine-rich repeat protein phosphatase · PMID 24892992 · 12 records
• Biochemical characterization of the POM-1 metallo-β-lactamase from Pseudomonas otitidis · PMID 25512428 · 12 records
• Biochemical characterization of the retaining glycosyltransferase glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis · PMID 25317963 · 16 records
• Biochemical Characterization of the Rice Cinnamyl Alcohol Dehydrogenase Gene Family · PMID 30332817 · 12 records
• Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea · PMID 21911565 · 9 records
• Biochemical characterization of the α-1,3-mannosidase AnGH92A from Aspergillus nidulans · PMID 41491408 · 3 records
• Biochemical characterization of trypsins from the hepatopancreas of Japanese sea bass (Lateolabrax japonicus) · PMID 21515400 · 12 records
• Biochemical characterization of two forms of 3-hydroxy-3-methylglutaryl-CoA reductase kinase from cauliflower (Brassica oleracia) · PMID 8112324 · 18 records
• Biochemical characterization of two glutamate dehydrogenases with different cofactor specificities from a hyperthermophilic archaeon Pyrobaculum calidifontis · PMID 23508687 · 10 records
• Biochemical characterization of two haloalkane dehalogenases: DccA from Caulobacter crescentus and DsaA from Saccharomonospora azurea · PMID 26833751 · 5 records
• Biochemical characterization of uronate dehydrogenases from three Pseudomonads, Chromohalobacter salixigens, and Polaromonas naphthalenivorans · PMID 25640726 · 23 records
• Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate · PMID 19264755 · 8 records
• Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family · PMID 12968022 · 8 records
• Biochemical elucidation of citrate accumulation in Synechocystis sp. PCC 6803 via kinetic analysis of aconitase · PMID 34429477 · 30 records
• Biochemical Functions of Glutathione S-Transferase Family of Salix babylonica · PMID 32308662 · 28 records
• Biochemical investigation of the tryptophan biosynthetic enzyme anthranilate phosphoribosyltransferase in plants · PMID 37659723 · 18 records
• Biochemical investigations using mass spectrometry to monitor JMJD6-catalysed hydroxylation of multi-lysine containing bromodomain-derived substrates · PMID 40046450 · 5 records
• Biochemical properties and expression profile of human prolyl dipeptidase DPP9 · PMID 19268648 · 12 records
• Biochemical properties and subcellular localization of tyrosine aminotransferases in Arabidopsis thaliana · PMID 27726859 · 19 records
• Biochemical properties and substrate specificity of GOB-38 in Elizabethkingia anophelis · PMID 39747310 · 11 records
• Biochemical properties of a Pseudomonas aminotransferase involved in caprolactam metabolism · PMID 31162815 · 29 records
• Biochemical properties of alcohol dehydrogenase from Drosophila lebanonensis · PMID 2943270 · 44 records
• Biochemical properties of ectoine hydroxylases from extremophiles and their wider taxonomic distribution among microorganisms · PMID 24714029 · 14 records
• Biochemical properties of GH94 cellodextrin phosphorylase THA_1941 from a thermophilic eubacterium Thermosipho africanus TCF52B with cellobiose phosphorylase activity · PMID 28687766 · 11 records
• Biochemical Properties of Human D-Amino Acid Oxidase · PMID 29326945 · 5 records
• Biochemical properties of mutant and wild-type fructose-1,6-bisphosphatases are consistent with the coupling of intra- and intersubunit conformational changes in the T- and R-state transition · PMID 8969189 · 6 records
• Biochemical properties of nematode O-acetylserine(thiol)lyase paralogs imply their distinct roles in hydrogen sulfide homeostasis · PMID 24100226 · 22 records
• Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate:quinone oxidoreductase, a potential drug target · PMID 29269266 · 5 records
• Biochemical Studies of Mycobacterial Fatty Acid Methyltransferase: A Catalyst for the Enzymatic Production of Biodiesel · PMID 26526103 · 10 records
• Biochemical, Structural, and Conformational Characterization of a Fungal Ethylene-Forming Enzyme · PMID 40052306 · 5 records
• Biochemical/spectroscopic characterization and preliminary X-ray analysis of a new aldehyde oxidoreductase isolated from Desulfovibrio desulfuricans ATCC 27774 · PMID 10679276 · 3 records
• Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor · PMID 18563898 · 4 records
• Biodegradation of Ephedrine Isomers by Arthrobacter sp. Strain TS-15: Discovery of Novel Ephedrine and Pseudoephedrine Dehydrogenases · PMID 31900306 · 6 records
• Biogenesis of Hydrogen Sulfide and Thioethers by Cystathionine Beta-Synthase · PMID 28874062 · 10 records
• Bioinformatic analysis of the fold type I PLP-dependent enzymes reveals determinants of reaction specificity in l-threonine aldolase from Aeromonas jandaei · PMID 29928580 · 32 records
• Bioinformatic and biochemical analysis of a novel maltose-forming α-amylase of the GH57 family in the hyperthermophilic archaeon Thermococcus sp. CL1 · PMID 24835094 · 4 records
• Bioinformatic and biochemical characterizations of C-S bond formation and cleavage enzymes in the fungus Neurospora crassa ergothioneine biosynthetic pathway · PMID 25275953 · 5 records
• Bioinformatics and Computationally Supported Redesign of Aspartase for β-Alanine Synthesis by Acrylic Acid Hydroamination · PMID 39839848 · 8 records
• Biological phosphorylation of an Unnatural Base Pair (UBP) using a Drosophila melanogaster deoxynucleoside kinase (DmdNK) mutant · PMID 28323896 · 8 records
• Biophysical and biochemical evidence for the role of acetate kinases (AckAs) in an acetogenic pathway in pathogenic spirochetes · PMID 39787173 · 14 records
• Biophysical and enzymatic properties of aminoglycoside adenylyltransferase AadA6 from Pseudomonas aeruginosa · PMID 29124199 · 6 records
• Bioproduction of L-Aspartic Acid and Cinnamic Acid by L-Aspartate Ammonia Lyase from Pseudomonas aeruginosa PAO1 · PMID 27988856 · 3 records
• Biosensor-guided directed evolution of aldehyde dehydrogenase for improved adipic acid production from caprolactone · PMID 41872847 · 4 records
• Biosynthesis of a central intermediate in hydrogen sulfide metabolism by a novel human sulfurtransferase and its yeast ortholog · PMID 24981631 · 29 records
• Biosynthesis of Nucleoside Diphosphoramidates in Campylobacter jejuni · PMID 29023101 · 3 records
• Biosynthesis of phytosterols. Kinetic mechanism for the enzymatic C-methylation of sterols · PMID 12807886 · 12 records
• Biosynthesis of pteridines in Escherichia coli. Structural and mechanistic similarity of dihydroneopterin-triphosphate epimerase and dihydroneopterin aldolase · PMID 9651328 · 11 records
• Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe · PMID 11856310 · 14 records
• Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme · PMID 17873868 · 5 records
• Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators · PMID 32324389 · 7 records
• Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS-PKS hybrid enzyme · PMID 26503170 · 3 records
• Biosynthesis of the nitrile glucosides rhodiocyanoside A and D and the cyanogenic glucosides lotaustralin and linamarin in Lotus japonicus · PMID 15122013 · 4 records
• Biosynthesis of vitamin B12: stepwise amidation of carboxyl groups b, d, e, and g of cobyrinic acid a,c-diamide is catalyzed by one enzyme in Pseudomonas denitrificans · PMID 1917839 · 13 records
• Biosynthesis, purification, and substrate specificity of severe acute respiratory syndrome coronavirus 3C-like proteinase · PMID 14561748 · 11 records
• Biosynthesized uricase with dual-terminus zwitterionic EKylation for prolonged elimination half-life and reduced immunogenicity · PMID 41709250 · 3 records
• Biotechnological potential and initial characterization of two novel sesquiterpene synthases from Basidiomycota Coniophora puteana for heterologous production of δ-cadinol · PMID 35440053 · 9 records
• Boosting Reversible Photocontrol of a Photoxenase by an Engineered Conformational Shift · PMID 41255148 · 48 records
• Bovine brain ketimine reductase · PMID 3191146 · 6 records
• Bovine lens aldehyde dehydrogenase. Kinetics and mechanism · PMID 6651766 · 12 records
• Bovine lens aldehyde reductase (aldose reductase). Purification, kinetics and mechanism · PMID 6426471 · 12 records
• Bovine liver glucose dehydrogenase: isolation and characterization · PMID 7092232 · 30 records
• Brassica juncea 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase 1: expression and characterization of recombinant wild-type and mutant enzymes · PMID 15233626 · 11 records
• Breaking symmetry: mutations engineered into R67 dihydrofolate reductase, a D2 symmetric homotetramer possessing a single active site pore · PMID 12501195 · 14 records
• Breaking the regioselectivity of indole prenyltransferases: identification of regular C3-prenylated hexahydropyrrolo[2,3-b]indoles as side products of the regular C2-prenyltransferase FtmPT1 · PMID 23090579 · 12 records
• Bridging Simulation and Sustainability: Laccase Immobilization on Bio-Polymeric Hybrids for Degradation of 17α-Ethinylestradiol in Water Systems · PMID 42110815 · 2 records
• Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back-conversion pathway in Arabidopsis · PMID 18583528 · 4 records
• Brighter NIR Bioluminescence System for Mammalian Cell Bioimaging Based on Engineered Railroadworm Luciferase and 6'-Aminoluciferin Analogues · PMID 42358773 · 7 records
• Broad spectrum aminoglycoside phosphotransferase type III from Enterococcus: overexpression, purification, and substrate specificity · PMID 8204627 · 11 records
• Broad substrate stereospecificity of the Mycobacterium tuberculosis 7-keto-8-aminopelargonic acid synthase: Spectroscopic and kinetic studies · PMID 16769720 · 3 records
• Broad-Spectrum Inhibitors for Conserved Unique Phosphoethanolamine Methyltransferases in Parasitic Nematodes Possess Anthelmintic Efficacy · PMID 37212658 · 12 records
• Broadening the Substrate Specificity of Cellobiose Phosphorylase from Clostridium thermocellum for Improved Transformation of Cellodextrin to Starch · PMID 37833899 · 8 records
• Butyryl-CoA dehydrogenase from Megasphaera elsdenii. Specificity of the catalytic reaction · PMID 6712628 · 17 records
• Butyryl-CoA:acetoacetate CoA-transferase from a lysine-fermenting Clostridium · PMID 624727 · 31 records
• Bypass of Methoxyamine-Adducted Abasic Sites by Eukaryotic Translesion DNA Polymerases · PMID 39859356 · 35 records
• C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis · PMID 17138693 · 10 records
• C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG · PMID 24066157 · 6 records
• C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes · PMID 34728636 · 3 records
• C-Glycosyltransferases catalyzing the formation of di-C-glucosyl flavonoids in citrus plants · PMID 28370711 · 5 records
• C-Terminal region of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase is involved in the interaction with prostaglandin substrates · PMID 11422365 · 24 records
• C1-Tetrahydrofolate synthase from rabbit liver. Structural and kinetic properties of the enzyme and its two domains · PMID 3871768 · 12 records
• C2α-carbanion-protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2-hydroxyacyl-CoA lyase · PMID 41606311 · 9 records
• Caenorhabditis elegans has two genes encoding functional d-aspartate oxidases · PMID 17140416 · 9 records
• Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability · PMID 21111690 · 4 records
• Calcium activation mechanism of a noncanonical aromatic L-amino acid decarboxylase from psilocybin mushroom Psilocybe cubensis · PMID 41748824 · 8 records
• Camphor pathway redux: functional recombinant expression of 2,5- and 3,6-diketocamphane monooxygenases of Pseudomonas putida ATCC 17453 with their cognate flavin reductase catalyzing Baeyer-Villiger… · PMID 23524667 · 3 records
• Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry · PMID 10951190 · 13 records
• Candida albicans utilizes a modified β-oxidation pathway for the degradation of toxic propionyl-CoA · PMID 24497638 · 6 records
• Carbamate transport in carbamoyl phosphate synthetase: a theoretical and experimental investigation · PMID 20187643 · 54 records
• Carbamoyl phosphate synthetase I of human liver. Purification, some properties and immunological cross-reactivity with the rat liver enzyme · PMID 7248316 · 3 records
• Carbohydrate deacetylase, a key enzyme in oxidative chitin degradation, is evolutionarily linked to amino acid deacetylase · PMID 40113045 · 6 records
• Carbohydrate metabolism in Thermoproteus tenax: in vivo utilization of the non-phosphorylative Entner-Doudoroff pathway and characterization of its first enzyme, glucose dehydrogenase · PMID 9238103 · 4 records
• Carbonyl reductase activity of sepiapterin reductase from rat erythrocytes · PMID 3904835 · 22 records
• Carbonyl reductase from human testis: purification and comparison with carbonyl reductase from human brain and rat testis · PMID 1540623 · 48 records
• Carboxymethylproline synthase from Pectobacterium carotorova: a multifaceted member of the crotonase superfamily · PMID 15595850 · 7 records
• Cardiolipin Stabilizes and Increases Catalytic Efficiency of Carnitine Palmitoyltransferase II and Its Variants S113L, P50H, and Y479F · PMID 34063237 · 16 records
• Catabolism of 1,5-anhydro-D-fructose in Sinorhizobium morelense S-30.7.5: discovery, characterization, and overexpression of a new 1,5-anhydro-D-fructose reductase and its application in sugar… · PMID 16461673 · 3 records
• Catalysis by human leukocyte elastase: mechanistic insights into specificity requirements · PMID 3646070 · 13 records
• Catalysis by the large subunit of the second beta-galactosidase of Escherichia coli in the absence of the small subunit · PMID 7492325 · 21 records
• Catalysis by the second class of tRNA(m1G37) methyl transferase requires a conserved proline · PMID 16768442 · 15 records
• Catalytic action of fuculose 1-phosphate aldolase (class II) as derived from structure-directed mutagenesis · PMID 10821675 · 15 records
• Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene · PMID 32101217 · 3 records
• Catalytic activity of human indoleamine 2,3-dioxygenase (hIDO1) at low oxygen · PMID 25712221 · 16 records
• Catalytic and inhibitor binding properties of zebrafish monoamine oxidase (zMAO): comparisons with human MAO A and MAO B · PMID 21354322 · 22 records
• Catalytic and inhibitor-binding properties of some active-site mutants of human carbonic anhydrase I · PMID 7758465 · 26 records
• Catalytic and redox properties of glycine oxidase from Bacillus subtilis · PMID 19254749 · 12 records
• Catalytic and regulatory roles of divalent metal cations on the phosphoryl-transfer mechanism of ADP-dependent sugar kinases from hyperthermophilic archaea · PMID 21906652 · 14 records
• Catalytic and structural characteristics of carp hepatopancreas D-amino acid oxidase expressed in Escherichia coli · PMID 15694590 · 9 records
• Catalytic and structural contributions for glutathione-binding residues in a Delta class glutathione S-transferase · PMID 15182230 · 15 records
• Catalytic and substrate promiscuity: distinct multiple chemistries catalysed by the phosphatase domain of receptor protein tyrosine phosphatase · PMID 27208174 · 5 records
• Catalytic and thermodynamic properties of a tannase produced by Aspergillus niger GH1 grown on polyurethane foam · PMID 21837378 · 10 records
• Catalytic consequences of experimental evolution: catalysis by a 'third-generation' evolvant of the second beta-galactosidase of Escherichia coli, ebgabcde, and by ebgabcd, a 'second-generation'… · PMID 8554546 · 22 records
• Catalytic contribution of threonine 244 in human ALDH2 · PMID 23295226 · 10 records
• Catalytic cycling in beta-phosphoglucomutase: a kinetic and structural analysis · PMID 15996095 · 8 records
• Catalytic cysteine of thymidylate synthase is activated upon substrate binding · PMID 10841779 · 17 records
• Catalytic Efficiency for the Chemoenzymatic Synthesis of Core Human Milk Oligosaccharides and Analogs via Sugar Oxazolines · PMID 42200609 · 12 records
• Catalytic features and crystal structure of a tau class glutathione transferase from Glycine max specifically upregulated in response to soybean mosaic virus infections · PMID 25479053 · 8 records
• Catalytic Features and Thermal Adaptation Mechanisms of a Deep Sea Bacterial Cutinase-Type Poly(Ethylene Terephthalate) Hydrolase · PMID 35557867 · 15 records
• Catalytic improvement and evolution of atrazine chlorohydrolase · PMID 19201959 · 13 records
• Catalytic mechanism and molecular recognition of E. coli UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase probed by mutagenesis · PMID 17176046 · 10 records
• Catalytic mechanism and three-dimensional structure of adenine deaminase · PMID 21247091 · 33 records
• Catalytic mechanism of active-site serine beta-lactamases: role of the conserved hydroxy group of the Lys-Thr(Ser)-Gly triad · PMID 8042993 · 97 records
• Catalytic mechanism of alpha-retaining glucosyl transfer by Corynebacterium callunae starch phosphorylase: the role of histidine-334 examined through kinetic characterization of site-directed… · PMID 15535798 · 24 records
• Catalytic mechanism of C-C hydrolase MhpC from Escherichia coli: kinetic analysis of His263 and Ser110 site-directed mutants · PMID 15663941 · 11 records
• Catalytic mechanism of Chlamydia trachomatis flavin-dependent thymidylate synthase · PMID 15591067 · 3 records
• Catalytic Mechanism of Cruzain from Trypanosoma cruzi As Determined from Solvent Kinetic Isotope Effects of Steady-State and Pre-Steady-State Kinetics · PMID 29336553 · 157 records
• Catalytic mechanism of cyclic di-GMP-specific phosphodiesterase: a study of the EAL domain-containing RocR from Pseudomonas aeruginosa · PMID 18344366 · 12 records
• Catalytic mechanism of dichloromethane dehalogenase from Methylophilus sp. strain DM11 · PMID 12974641 · 13 records
• Catalytic mechanism of Escherichia coli endonuclease VIII: roles of the intercalation loop and the zinc finger · PMID 17002303 · 75 records
• Catalytic mechanism of glycine N-methyltransferase · PMID 12859184 · 12 records
• Catalytic mechanism of retaining alpha-galactosidase belonging to glycoside hydrolase family 97 · PMID 19646996 · 4 records
• Catalytic mechanism of S-ribosylhomocysteinase (LuxS): stereochemical course and kinetic isotope effect of proton transfer reactions · PMID 15287744 · 10 records
• Catalytic mechanism of S-type phycobiliprotein lyase: chaperone-like action and functional amino acid residues · PMID 19864423 · 9 records
• Catalytic mechanism of short ethoxy chain nonylphenol dehydrogenase belonging to a polyethylene glycol dehydrogenase group in the GMC oxidoreductase family · PMID 23306149 · 8 records
• Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase · PMID 14756554 · 11 records
• Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis · PMID 12627955 · 31 records
• Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton · PMID 12756244 · 6 records
• Catalytic properties and crystal structure of quinoprotein aldose sugar dehydrogenase from hyperthermophilic archaeon Pyrobaculum aerophilum · PMID 20692227 · 9 records
• Catalytic properties of a short manganese peroxidase from Irpex lacteus F17 and the role of Glu166 in the Mn²⁺-independent activity · PMID 31226373 · 14 records
• Catalytic properties of dihydroorotate dehydrogenase from Saccharomyces cerevisiae: studies on pH, alternate substrates, and inhibitors · PMID 10871048 · 7 records
• Catalytic properties of mutant 23 S ribosomes resistant to oxazolidinones · PMID 12645571 · 8 records
• Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase · PMID 9367528 · 13 records
• Catalytic Properties of NADP-Reducing Enzymes from Streptococcus cristatus ATCC 51100 · PMID 42650878 · 16 records
• Catalytic properties of polymorphic human cytochrome P450 1B1 variants · PMID 10426814 · 20 records
• Catalytic properties of the cysteine aminopeptidase PepC, a bacterial bleomycin hydrolase · PMID 9546047 · 34 records
• Catalytic properties of the plant cytochrome P450 CYP73 expressed in yeast. Substrate specificity of a cinnamate hydroxylase · PMID 7925408 · 5 records
• Catalytic properties of thimet oligopeptidase H600A mutant · PMID 20226173 · 20 records
• Catalytic properties of two Rhizopus oryzae 99-880 glucoamylase enzymes without starch binding domains expressed in Pichia pastoris · PMID 20549574 · 15 records
• Catalytic properties of X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis subsp. cremoris nTR · PMID 1369485 · 7 records
• Catalytic reaction of cytokinin dehydrogenase: preference for quinones as electron acceptors · PMID 14965342 · 48 records
• Catalytic reaction profile for NADH-dependent reduction of aromatic aldehydes by xylose reductase from Candida tenuis · PMID 12003638 · 60 records
• Catalytic residues and an electrostatic sandwich that promote enolpyruvyl shikimate 3-phosphate synthase (AroA) catalysis · PMID 19271774 · 28 records
• Catalytic residues and substrate specificity of recombinant human tripeptidyl peptidase I (CLN2) · PMID 16091586 · 13 records
• Catalytic residues Lys197 and Arg199 of Bacillus subtilis phosphoribosyl diphosphate synthase. Alanine-scanning mutagenesis of the flexible catalytic loop · PMID 16008562 · 15 records
• Catalytic role for arginine 188 in the C-C hydrolase catalytic mechanism for Escherichia coli MhpC and Burkholderia xenovorans LB400 BphD · PMID 17029402 · 10 records
• Catalytic Role of the Substrate Defines Specificity of Therapeutic l-Asparaginase · PMID 26142822 · 7 records
• Catalytic site cooperativity in dimeric methylthioadenosine nucleosidase · PMID 24502544 · 6 records
• Catalytic surface radical in dye-decolorizing peroxidase: a computational, spectroscopic and site-directed mutagenesis study · PMID 25495127 · 88 records
• Catechol 1,2-dioxygenase from the Gram-positive Rhodococcus opacus 1CP: quantitative structure/activity relationship and the crystal structures of native enzyme and catechols adducts · PMID 20040374 · 18 records
• Catechol dioxygenases from Escherichia coli (MhpB) and Alcaligenes eutrophus (MpcI): sequence analysis and biochemical properties of a third family of extradiol dioxygenases · PMID 8752345 · 9 records
• Catecholase activity associated with copper-S100B · PMID 12693934 · 8 records
• Cathepsin B carboxydipeptidase specificity analysis using internally quenched fluorescent peptides · PMID 12201820 · 58 records
• Cation dependent O-methyltransferases from rice · PMID 17943312 · 8 records
• Cations modulate the substrate specificity of bifunctional class I O-methyltransferase from Ammi majus · PMID 15556611 · 10 records
• Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases · PMID 16981730 · 6 records
• cDNA cloning and characterization of a new human microsomal NAD+-dependent dehydrogenase that oxidizes all-trans-retinol and 3alpha-hydroxysteroids · PMID 9677409 · 7 records
• cDNA cloning, expression and characterization of human prostaglandin F synthase · PMID 10622721 · 6 records
• cDNA cloning, expression, and mutagenesis study of liver-type prostaglandin F synthase · PMID 9867836 · 24 records
• cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase. Candidate for selenium delivery protein in selenoprotein synthesis · PMID 10692412 · 3 records
• Cefepime-taniborbactam and ceftibuten-ledaborbactam maintain activity against KPC variants that lead to ceftazidime-avibactam resistance · PMID 39927783 · 28 records
• Ceftazidime and aztreonam resistance in Providencia stuartii: characterization of a natural TEM-derived extended-spectrum beta-lactamase, TEM-60 · PMID 9624494 · 14 records
• Cell permeable cocaine esterases constructed by chemical conjugation and genetic recombination · PMID 22404344 · 12 records
• Cell polarity control by an unconventional G-protein complex in bacteria · PMID 42297786 · 10 records
• Cell-specific activity of neprilysin 2 isoforms and enzymic specificity compared with neprilysin · PMID 11964170 · 48 records
• Cellobiose dehydrogenase from the ligninolytic basidiomycete Ceriporiopsis subvermispora · PMID 19270118 · 13 records
• Cellodextrin phosphorylase from Ruminiclostridium thermocellum: X-ray crystal structure and substrate specificity analysis · PMID 28760417 · 6 records
• Cephalosporin substrate specificity determinants of TEM-1 beta-lactamase · PMID 9360991 · 30 records
• Cg2091 encodes a polyphosphate/ATP-dependent glucokinase of Corynebacterium glutamicum · PMID 20379711 · 15 records
• Change of the donor substrate specificity of Clostridium difficile toxin B by site-directed mutagenesis · PMID 16157585 · 9 records
• Changing the amino acid specificity of yeast tyrosyl-tRNA synthetase by genetic engineering · PMID 11530018 · 12 records
• Changing the metal ion selectivity of rabbit muscle enolase by mutagenesis: effects of the G37A and G41A mutations · PMID 15752688 · 15 records
• Changing the regioselectivity of a P450 from C15 to C11 hydroxylation of progesterone · PMID 22532270 · 15 records
• Characterisation and preliminary X-ray diffraction analysis of human pancreatic procarboxypeptidase A2 · PMID 9450539 · 7 records
• Characterisation of a cold-adapted, thermostable glucokinase from psychrophilic Pseudoalteromonas sp. AS-131 reveals how the enzyme achieves high thermal stability without loss of cold adaptation · PMID 41397938 · 30 records
• Characterisation of a novel mouse liver aldo-keto reductase AKR7A5 · PMID 12123834 · 25 records
• Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase · PMID 11514237 · 3 records
• Characterisation of KLUA-9, a beta-lactamase from extended-spectrum cephalosporin-susceptible Kluyvera ascorbata, and genetic organisation of bla(KLUA-9) · PMID 17196371 · 12 records
• Characterisation of recombinant pyranose oxidase from the cultivated mycorrhizal basidiomycete Lyophyllum shimeji (hon-shimeji) · PMID 20630076 · 15 records
• Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition · PMID 20350571 · 5 records
• Characterisation of the flavin adenine dinucleotide binding region of Myxococcus xanthus protoporphyrinogen oxidase · PMID 29124218 · 8 records
• Characterisation of the N-Methyltransferase SgPsmC: Application in the Kinetic Resolution of Pyrroloindolines · PMID 41273157 · 2 records
• Characterisation of the organophosphate hydrolase catalytic activity of SsoPox · PMID 23139857 · 30 records
• Characterisation of three fungal glucuronoyl esterases on glucuronic acid ester model compounds · PMID 28429057 · 3 records
• Characteristic properties of endoplasmic reticulum membrane m-calpain, calpastatin and lumen m-calpain: a comparative study between membrane and lumen m-calpains · PMID 20123702 · 8 records
• Characterization and amino acid sequence analysis of a new oxyimino cephalosporin-hydrolyzing class A beta-lactamase from Serratia fonticola CUV · PMID 9300809 · 20 records
• Characterization and application of calcium-dependent β-propeller phytase from Bacillus amyloliquefaciens DS11 · PMID 22775008 · 18 records
• Characterization and cloning of the chlorophyll-degrading enzyme pheophorbidase from cotyledons of radish · PMID 16384908 · 6 records
• Characterization and crystal structure determination of β-1,2-mannobiose phosphorylase from Listeria innocua · PMID 26632508 · 8 records
• Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase · PMID 27873437 · 20 records
• Characterization and Dye Decolorization Potential of Two Laccases from the Marine-Derived Fungus Pestalotiopsis sp. · PMID 30991752 · 8 records
• Characterization and engineering of the bifunctional N- and O-glucosyltransferase involved in xenobiotic metabolism in plants · PMID 18077347 · 13 records
• Characterization and evolution of an activator-independent methanol dehydrogenase from Cupriavidus necator N-1 · PMID 26846745 · 23 records
• Characterization and expression of human bifunctional 3'-phosphoadenosine 5'-phosphosulphate synthase isoforms · PMID 11931637 · 6 records
• Characterization and functional analysis of a recombinant tau class glutathione transferase GmGSTU2-2 from Glycine max · PMID 27103493 · 8 records
• Characterization and functional reconstruction of a highly productive germacrene A synthase from Liriodendron chinense · PMID 40011225 · 1 record
• Characterization and heterologous gene expression of a novel esterase from Lactobacillus casei CL96 · PMID 15184114 · 6 records
• Characterization and improved properties of Glutamine synthetase from Providencia vermicola by site-directed mutagenesis · PMID 30353099 · 6 records
• Characterization and improvement of substrate-binding affinity of D-aspartate oxidase of the thermophilic fungus Thermomyces dupontii · PMID 30937498 · 8 records
• Characterization and inactivation of an agmatine deiminase from Helicobacter pylori · PMID 20036411 · 2 records
• Characterization and interaction studies of two isoforms of the dual localized 3-mercaptopyruvate sulfurtransferase TUM1 from humans · PMID 25336638 · 8 records
• Characterization and kinetic analysis of enzyme-substrate recognition by three recombinant lactococcal PepVs · PMID 16962986 · 60 records
• Characterization and kinetic analysis of enzyme-substrate recognition by three recombinant lactococcal tripeptidases · PMID 15752689 · 10 records
• Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis · PMID 19182993 · 3 records
• Characterization and manipulation of the acyl chain selectivity of fatty acid amide hydrolase · PMID 11352748 · 31 records
• Characterization and mode of action of an exopolygalacturonase from the hyperthermophilic bacterium Thermotoga maritima · PMID 16262687 · 8 records
• Characterization and mutagenesis of Gal/GlcNAc-6-O-sulfotransferases · PMID 12501187 · 12 records
• Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency · PMID 28388636 · 5 records
• Characterization and nucleotide binding properties of a mutant dihydropteridine reductase containing an aspartate 37-isoleucine replacement · PMID 1639779 · 8 records
• Characterization and Purification of an Aldose Reductase from the Acidophilic and Thermophilic Red Alga Galdieria sulphuraria · PMID 12223702 · 12 records
• Characterization and redox regulation of Plasmodium falciparum methionine adenosyltransferase · PMID 27466371 · 8 records
• Characterization and regulation of a bacterial sugar phosphatase of the haloalkanoate dehalogenase superfamily, AraL, from Bacillus subtilis · PMID 21575135 · 8 records
• Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase · PMID 10861207 · 2 records
• Characterization and selective inhibition of myristoyl-CoA:protein N-myristoyltransferase from Trypanosoma brucei and Leishmania major · PMID 16480339 · 4 records
• Characterization and sequence of the Chryseobacterium (Flavobacterium) meningosepticum carbapenemase: a new molecular class B beta-lactamase showing a broad substrate profile · PMID 9576862 · 7 records
• Characterization and Soluble Expression of D-Hydantoinase from Pseudomonas fluorescens for the Synthesis of D-Amino Acids · PMID 26821258 · 6 records
• Characterization and structural analyses of a novel glycosyltransferase acting on the β-1,2-glucosidic linkages · PMID 35065074 · 20 records
• Characterization and use of a bacterial lignin peroxidase with an improved manganese-oxidative activity · PMID 30302519 · 8 records
• Characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme involved in isopentenyl diphosphate biosynthesis, and identification of its catalytic amino acid residues · PMID 10787409 · 14 records
• Characterization of 2-enoyl thioester reductase from mammals. An ortholog of YBR026p/MRF1'p of the yeast mitochondrial fatty acid synthesis type II · PMID 12654921 · 3 records
• Characterization of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A-dependent enzyme involved in peptide fermentation by hyperthermophilic archaea · PMID 8550513 · 30 records
• Characterization of 3-ketosteroid 9α-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis · PMID 19234303 · 4 records
• Characterization of 4-hydroxyphenylpyruvate dioxygenases, inhibition by herbicides and engineering for herbicide tolerance in crops · PMID 31027586 · 31 records
• Characterization of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases from Borrelia burgdorferi: Antibiotic targets for Lyme disease · PMID 31669585 · 9 records
• Characterization of a (2R,3R)-2,3-butanediol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product. Disruption and induction of the gene · PMID 10938079 · 6 records
• Characterization of a 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase from the gram-negative bacterium Comamonas testosteroni · PMID 8944761 · 30 records
• Characterization of a beta-hydroxybutyryl-CoA dehydrogenase from Mycobacterium tuberculosis · PMID 20378648 · 4 records
• Characterization of a beta-N-acetylhexosaminidase and a beta-N-acetylglucosaminidase/beta-glucosidase from Cellulomonas fimi · PMID 16762038 · 4 records
• Characterization of a butyrate kinase from Desulfovibrio vulgaris str. Hildenborough · PMID 32166312 · 7 records
• Characterization of a caffeic acid 3-O-methyltransferase from wheat and its function in lignin biosynthesis · PMID 17976886 · 7 records
• Characterization of a caffeoyl-CoA O-methyltransferase-like enzyme involved in biosynthesis of polymethoxylated flavones in Citrus reticulata · PMID 32182355 · 8 records
• Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism · PMID 19875455 · 3 records
• Characterization of a cellobiose dehydrogenase from Humicola insolens · PMID 9461557 · 11 records
• Characterization of a cold-adapted glutathione synthetase from the psychrophile Pseudoalteromonas haloplanktis · PMID 22777241 · 8 records
• Characterization of a cytosolic malate dehydrogenase cDNA which encodes an isozyme toward oxaloacetate reduction in wheat · PMID 15388227 · 6 records
• Characterization of a Dye-Decolorizing Peroxidase from Irpex lacteus Expressed in Escherichia coli: An Enzyme with Wide Substrate Specificity Able to Transform Lignosulfonates · PMID 33922393 · 8 records
• Characterization of a F280N variant of L-arabinose isomerase from Geobacillus thermodenitrificans identified as a D-galactose isomerase · PMID 24880627 · 2 records
• Characterization of a fibrinogen-clotting enzyme from Trimeresurus stejnegeri venom, and comparative study with other venom proteases · PMID 9604287 · 21 records
• Characterization of a Flavonoid 3'/5'/7-O-Methyltransferase from Citrus reticulata and Evaluation of the In Vitro Cytotoxicity of Its Methylated Products · PMID 32075249 · 3 records
• Characterization of a flavonol 3-O-methyltransferase in the trichomes of the wild tomato species Solanum habrochaites · PMID 22711283 · 4 records
• Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine · PMID 20060817 · 5 records
• Characterization of a leucine aminopeptidase of Babesia gibsoni · PMID 19549347 · 6 records
• Characterization of a low redox potential laccase from the basidiomycete C30 · PMID 12473107 · 8 records
• Characterization of a mildly alkalophilic and thermostable recombinant Thermus thermophilus laccase with applications in decolourization of dyes · PMID 29063287 · 6 records
• Characterization of a new cobalt-containing nitrile hydratase purified from urea-induced cells of Rhodococcus rhodochrous J1 · PMID 2013281 · 13 records
• Characterization of a new extended-spectrum beta-lactamase (TEM-87) isolated in Proteus mirabilis during an Italian survey · PMID 11850290 · 10 records
• Characterization of a new member of the flavoprotein disulfide reductase family of enzymes from Mycobacterium tuberculosis · PMID 15456792 · 12 records
• Characterization of a new pantothenate kinase isoform from Helicobacter pylori · PMID 15795230 · 4 records
• Characterization of a novel 3-hydroxybutyrate dehydrogenase from Ralstonia pickettii T1 · PMID 19219638 · 4 records
• Characterization of a novel aminoglycoside resistance gene, aadA34, identified from Serratia ureilytica S24 · PMID 41929691 · 2 records
• Characterization of a novel Aspergillus oryzae tannase expressed in Pichia pastoris · PMID 29859669 · 6 records
• Characterization of a novel bifunctional endo-β-1,4-glucanase/mannanase from Aspergillus oryzae · PMID 42098350 · 2 records
• Characterization of a Novel cis-3-Hydroxy-l-Proline Dehydratase and a trans-3-Hydroxy-l-Proline Dehydratase from Bacteria · PMID 28559297 · 5 records
• Characterization of a novel D-lyxose isomerase from Cohnella laevoribosii RI-39 sp. nov · PMID 17189362 · 3 records
• Characterization of a novel D-sorbitol dehydrogenase from Faunimonas pinastri A52C2 · PMID 39869196 · 1 record
• Characterization of a novel debranching enzyme from Nostoc punctiforme possessing a high specificity for long branched chains · PMID 19010304 · 13 records
• Characterization of a novel dye-decolorizing peroxidase (DyP)-type enzyme from Irpex lacteus and its application in enzymatic hydrolysis of wheat straw · PMID 23666335 · 6 records
• Characterization of a novel moderate-substrate specificity amino acid racemase from the hyperthermophilic archaeon Thermococcus litoralis · PMID 33942867 · 4 records
• Characterization of a novel N-acetylneuraminic acid lyase favoring industrial N-acetylneuraminic acid synthesis · PMID 25799411 · 7 records
• Characterization of a novel NADP(+)-dependent D-arabitol dehydrogenase from the plant pathogen Uromyces fabae · PMID 15796718 · 12 records
• Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1 · PMID 12644499 · 6 records
• Characterization of a novel type of human microsomal 3alpha -hydroxysteroid dehydrogenase: unique tissue distribution and catalytic properties · PMID 11294878 · 7 records
• Characterization of a novel zinc-containing, lysine-specific aminopeptidase from the hyperthermophilic archaeon Pyrococcus furiosus · PMID 15743956 · 5 records
• Characterization of a Novel, Cold-Adapted, and Thermostable Laccase-Like Enzyme With High Tolerance for Organic Solvents and Salt and Potent Dye Decolorization Ability, Derived From a Marine… · PMID 30568647 · 5 records
• Characterization of a petunia acetyltransferase involved in the biosynthesis of the floral volatile isoeugenol · PMID 17241449 · 8 records
• Characterization of a phenylacetate-CoA ligase from Penicillium chrysogenum · PMID 18834333 · 75 records
• Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX · PMID 17630782 · 24 records
• Characterization of a phosphotriesterase-like lactonase from the hyperthermoacidophilic crenarchaeon Vulcanisaeta moutnovskia · PMID 24858677 · 8 records
• Characterization of a recombinant 7,8-linoleate diol synthase from Glomerella cingulate · PMID 26577673 · 12 records
• Characterization of a recombinant L-rhamnose isomerase from Dictyoglomus turgidum and its application for L-rhamnulose production · PMID 23070627 · 7 records
• Characterization of a SAM-dependent fluorinase from a latent biosynthetic pathway for fluoroacetate and 4-fluorothreonine formation in Nocardia brasiliensis · PMID 24795808 · 4 records
• Characterization of a sulfur-regulated oxygenative alkylsulfatase from Pseudomonas putida S-313 · PMID 10913158 · 8 records
• Characterization of a thermoacidophilic L-arabinose isomerase from Alicyclobacillus acidocaldarius: role of Lys-269 in pH optimum · PMID 16332764 · 13 records
• Characterization of a thermophilic L-rhamnose isomerase from Caldicellulosiruptor saccharolyticus ATCC 43494 · PMID 21761877 · 5 records
• Characterization of a thermophilic L-rhamnose isomerase from Thermoanaerobacterium saccharolyticum NTOU1 · PMID 20822145 · 5 records
• Characterization of a thiamin diphosphate-dependent phenylpyruvate decarboxylase from Saccharomyces cerevisiae · PMID 21501384 · 41 records
• Characterization of a transient covalent adduct formed during dimethylarginine dimethylaminohydrolase catalysis · PMID 15865451 · 6 records
• Characterization of a tryptophan 6-halogenase from Streptomyces toxytricini · PMID 21424165 · 1 record
• Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli · PMID 10480865 · 15 records
• Characterization of a zinc-containing alcohol dehydrogenase with stereoselectivity from the hyperthermophilic archaeon Thermococcus guaymasensis · PMID 21515780 · 9 records
• Characterization of a β-Glucosidase from Fragaria × ananassa: Substrate Specificity, Catalytic Efficiency, and Structural Insights · PMID 42794075 · 8 records
• Characterization of acetovanillone degradation in wild-type and engineered Rhodococcus aromaticivorans RHA1 · PMID 41860218 · 1 record
• Characterization of active site residues of nitroalkane oxidase · PMID 20056514 · 11 records
• Characterization of active site variants of xanthine hydroxylase from Aspergillus nidulans · PMID 18036331 · 24 records
• Characterization of alpha-Galactosidase from Cucumber Leaves · PMID 16661511 · 8 records
• Characterization of amine oxidases from Arthrobacter aurescens and application for determination of biogenic amines · PMID 23225177 · 9 records
• Characterization of amino acid aminotransferases of Methanococcus aeolicus · PMID 1729242 · 28 records
• Characterization of an actin-targeting ADP-ribosyltransferase from Aeromonas hydrophila · PMID 22969084 · 14 records
• Characterization of an acyl-coA thioesterase that functions as a major regulator of peroxisomal lipid metabolism · PMID 11673457 · 27 records
• Characterization of an acyltransferase capable of synthesizing benzylbenzoate and other volatile esters in flowers and damaged leaves of Clarkia breweri · PMID 12226525 · 9 records
• Characterization of an alcohol dehydrogenase from the Cyanobacterium Synechocystis sp. strain PCC 6803 that responds to environmental stress conditions via the Hik34-Rre1 two-component system · PMID 19411329 · 12 records
• Characterization of an Aldehyde Oxidoreductase From the Mesophilic Bacterium Aromatoleum aromaticum EbN1, a Member of a New Subfamily of Tungsten-Containing Enzymes · PMID 30766522 · 8 records
• Characterization of an aldolase-dehydrogenase complex from the cholesterol degradation pathway of Mycobacterium tuberculosis · PMID 23614353 · 20 records
• Characterization of an aldolase-dehydrogenase complex that exhibits substrate channeling in the polychlorinated biphenyls degradation pathway · PMID 19476337 · 16 records
• Characterization of an allylic/benzyl alcohol dehydrogenase from Yokenella sp. strain WZY002, an organism potentially useful for the synthesis of α,β-unsaturated alcohols from allylic aldehydes and… · PMID 24509923 · 6 records
• Characterization of an archaeal medium-chain acyl coenzyme A synthetase from Methanosarcina acetivorans · PMID 20851904 · 14 records
• Characterization of an aryl-alcohol oxidase from the plant saprophytic basidiomycete Coprinopsis cinerea with broad substrate specificity against aromatic alcohols · PMID 29785669 · 27 records
• Characterization of an exo-acting intracellular alpha-amylase from the hyperthermophilic bacterium Thermotoga neapolitana · PMID 19834705 · 5 records
• Characterization of an L-phosphinothricin resistant glutamine synthetase from Exiguobacterium sp. and its improvement · PMID 28175947 · 8 records
• Characterization of an NAD(P)⁺-dependent meso-diaminopimelate dehydrogenase from Thermosyntropha lipolytica · PMID 32599299 · 3 records
• Characterization of an NADPH-dependent 17β-hydroxysteroid dehydrogenase from a urinary tract bacterial isolate · PMID 41845996 · 4 records
• Characterization of an oligomeric carbonyl reductase of dog liver: its identity with peroxisomal tetrameric carbonyl reductase · PMID 17827741 · 22 records
• Characterization of and functional evidence for Ste27 of Streptomyces sp. 139 as a novel spermine/spermidine acetyltransferase · PMID 22313365 · 5 records
• Characterization of Arabidopsis thaliana Hydroxyphenylpyruvate Reductases in the Tyrosine Conversion Pathway · PMID 30233632 · 7 records
• Characterization of aromatic aminotransferases from the hyperthermophilic archaeon Thermococcus litoralis · PMID 8125113 · 8 records
• Characterization of bacterial homocitrate synthase involved in lysine biosynthesis · PMID 12095615 · 4 records
• Characterization of bacterial NMN deamidase as a Ser/Lys hydrolase expands diversity of serine amidohydrolases · PMID 24530526 · 4 records
• Characterization of butyrylcholinesterase from porcine milk · PMID 29908755 · 8 records
• Characterization of C-S lyase from Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 and its potential role in food flavour applications · PMID 28003427 · 8 records
• Characterization of Carboxylic Acid Reductases as Enzymes in the Toolbox for Synthetic Chemistry · PMID 28450969 · 77 records
• Characterization of cell-bound papain-soluble beta-lactamases in BRO-1 and BRO-2 producing strains of Moraxella (Branhamella) catarrhalis and Moraxella nonliquefaciens · PMID 1396750 · 28 records
• Characterization of chicken-liver glutathione S-transferase (GST) A1-1 and A2-2 isoenzymes and their site-directed mutants heterologously expressed in Escherichia coli: identification of Lys-15 and… · PMID 9359434 · 16 records
• Characterization of chondroitin sulfate lyase ABC from Bacteroides thetaiotaomicron WAL2926 · PMID 18512954 · 15 records
• Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori. An aldehyde dismutating enzyme · PMID 15720399 · 13 records
• Characterization of cis-4-hydroxy-D-proline dehydrogenase from Sinorhizobium meliloti · PMID 29191113 · 8 records
• Characterization of CmaA, an adenylation-thiolation didomain enzyme involved in the biosynthesis of coronatine · PMID 14679222 · 20 records
• Characterization of cold-adapted Atlantic cod (Gadus morhua) trypsin I--kinetic parameters, autolysis and thermal stability · PMID 19913635 · 9 records
• Characterization of Coturnix quail liver alcohol dehydrogenase enzymes · PMID 2789998 · 13 records
• Characterization of cross-linked immobilized arylesterase from Gluconobacter oxydans 621H with activity toward cephalosporin C and 7-aminocephalosporanic acid · PMID 26443058 · 12 records
• Characterization of CYP76M5-8 indicates metabolic plasticity within a plant biosynthetic gene cluster · PMID 22215681 · 8 records
• Characterization of Danio rerio Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase, the structural prototype of the ADPRibase-Mn-like protein family · PMID 22848751 · 13 records
• Characterization of DcsC, a PLP-independent racemase involved in the biosynthesis of D-cycloserine · PMID 22307920 · 2 records
• Characterization of dihydrodipicolinate reductase from Thermotoga maritima reveals evolution of substrate binding kinetics · PMID 18250105 · 6 records
• Characterization of disease-related 5beta-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency · PMID 20522910 · 6 records
• Characterization of dTDP-4-dehydrorhamnose 3,5-epimerase and dTDP-4-dehydrorhamnose reductase, required for dTDP-L-rhamnose biosynthesis in Salmonella enterica serovar Typhimurium LT2 · PMID 10455186 · 5 records
• Characterization of Dye-decolorizing Peroxidase (DyP) from Thermomonospora curvata Reveals Unique Catalytic Properties of A-type DyPs · PMID 26205819 · 14 records
• Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides · PMID 12560336 · 5 records
• Characterization of EntF as a serine-activating enzyme · PMID 1338974 · 6 records
• Characterization of enzymes involved in the central metabolism of Gluconobacter oxydans · PMID 20676631 · 13 records
• Characterization of flavonoid 7-O-glucosyltransferase from Arabidopsis thaliana · PMID 16794327 · 3 records
• Characterization of four beta-lactamases produced by Staphylococcus aureus · PMID 1605608 · 67 records
• Characterization of four substrates emphasizes kinetic similarity between insect and human C-domain angiotensin-converting enzyme · PMID 12135492 · 22 records
• Characterization of glutamate-cysteine ligase and glutathione synthetase from the δ-proteobacterium Myxococcus xanthus · PMID 35277888 · 25 records
• Characterization of glutathione amide reductase from Chromatium gracile. Identification of a novel thiol peroxidase (Prx/Grx) fueled by glutathione amide redox cycling · PMID 11399772 · 4 records
• Characterization of glutathione-S-transferases in zebrafish (Danio rerio) · PMID 25461745 · 34 records
• Characterization of glycosyl hydrolase family 3 beta-N-acetylglucosaminidases from Thermotoga maritima and Thermotoga neapolitana · PMID 19914575 · 6 records
• Characterization of GUA-1, a chromosomally encoded ESBL from Pseudomonas guariconensis-like · PMID 42377112 · 7 records
• Characterization of hbzE-encoded gentisate 1,2-dioxygenase from Pseudomonas alcaligenes NCIMB 9867 · PMID 17720458 · 6 records
• Characterization of herpes simplex virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity · PMID 12192082 · 12 records
• Characterization of heterodimeric alkaline phosphatases from Escherichia coli: an investigation of intragenic complementation · PMID 11099386 · 65 records
• Characterization of homoisocitrate dehydrogenase involved in lysine biosynthesis of an extremely thermophilic bacterium, Thermus thermophilus HB27, and evolutionary implication of… · PMID 12427751 · 4 records
• Characterization of human DHRS4: an inducible short-chain dehydrogenase/reductase enzyme with 3beta-hydroxysteroid dehydrogenase activity · PMID 18571493 · 37 records
• Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase · PMID 16380372 · 4 records
• Characterization of human lysophospholipid acyltransferase 3 · PMID 19351971 · 1 record
• Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis · PMID 21742010 · 12 records
• Characterization of human type I and type II IMP dehydrogenases · PMID 7903306 · 8 records
• Characterization of hydroxycinnamoyltransferase from rice and its application for biological synthesis of hydroxycinnamoyl glycerols · PMID 22285622 · 5 records
• Characterization of inosine-uridine nucleoside hydrolase (RihC) from Escherichia coli · PMID 24473221 · 6 records
• Characterization of Ke 6, a new 17beta-hydroxysteroid dehydrogenase, and its expression in gonadal tissues · PMID 9712896 · 4 records
• Characterization of KPC-160, a novel Ω-loop-deleted KPC variant on a dual-copy plasmid that confers cefiderocol resistance · PMID 42089618 · 8 records
• Characterization of malate dehydrogenase from the hyperthermophilic archaeon Pyrobaculum islandicum · PMID 17487443 · 5 records
• Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization · PMID 21803176 · 28 records
• Characterization of multicopper oxidase CopA from Pseudomonas putida KT2440 and Pseudomonas fluorescens Pf-5: Involvement in bacterial lignin oxidation · PMID 30347180 · 6 records
• Characterization of Mycobacterium tuberculosis diaminopimelic acid epimerase: paired cysteine residues are crucial for racemization · PMID 18269631 · 3 records
• Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase · PMID 14556638 · 14 records
• Characterization of N-acetylneuraminic acid synthase isoenzyme 1 from Campylobacter jejuni · PMID 15200387 · 5 records
• Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum · PMID 10887194 · 18 records
• Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin · PMID 17539640 · 7 records
• Characterization of new recombinant 3-ketosteroid-Δ¹-dehydrogenases for the biotransformation of steroids · PMID 28634849 · 27 records
• Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway · PMID 19454282 · 7 records
• Characterization of phenylpropene O-methyltransferases from sweet basil: facile change of substrate specificity and convergent evolution within a plant O-methyltransferase family · PMID 11884690 · 9 records
• Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target · PMID 30098336 · 6 records
• Characterization of Plasmodium falciparum serine hydroxymethyltransferase-A potential antimalarial target · PMID 19591881 · 7 records
• Characterization of porcine alpha-class glutathione transferase A1-1 · PMID 21172301 · 6 records
• Characterization of Porphyromonas gingivalis sialidase and disruption of its role in host-pathogen interactions · PMID 31517596 · 6 records
• Characterization of prolidase activity in erythrocytes from a patient with prolidase deficiency: comparison with prolidase I and II purified from normal human erythrocytes · PMID 16009141 · 16 records
• Characterization of putative hydrophobic substrate binding site residues of a Delta class glutathione transferase from Anopheles dirus · PMID 18760991 · 37 records
• Characterization of pyranose dehydrogenase from Agaricus meleagris and its application in the C-2 specific conversion of D-galactose · PMID 18083263 · 21 records
• Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2 · PMID 16359636 · 29 records
• Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues · PMID 22475552 · 9 records
• Characterization of rabbit morphine 6-dehydrogenase and two NAD(+)-dependent 3α(17β)-hydroxysteroid dehydrogenases · PMID 23228597 · 103 records
• Characterization of RASA-1, a novel class A extended-spectrum beta-lactamase from Riemerella anatipestifer · PMID 35580446 · 10 records
• Characterization of rat and human CYP2J enzymes as Vitamin D 25-hydroxylases · PMID 16842832 · 6 records
• Characterization of recombinant Aspergillus fumigatus mannitol-1-phosphate 5-dehydrogenase and its application for the stereoselective synthesis of protio and deuterio forms of D-mannitol… · PMID 18452897 · 6 records
• Characterization of recombinant beta-fructofuranosidase from Bifidobacterium adolescentis G1 · PMID 20380746 · 6 records
• Characterization of recombinant diaminopropionate ammonia-lyase from Escherichia coli and Salmonella typhimurium · PMID 12821154 · 6 records
• Characterization of recombinant Dictyostelium discoideum sepiapterin reductase expressed in E. coli · PMID 10987137 · 2 records
• Characterization of recombinant fructose-1,6-bisphosphatase gene mutations: evidence of inhibition/activation of FBPase protein by gene mutation · PMID 30683805 · 13 records
• Characterization of recombinant fructose-1,6-bisphosphate aldolase from Methylococcus capsulatus Bath · PMID 20673213 · 6 records
• Characterization of Recombinant GMPR from Pocillopora damicornis and Potential Mechanisms of Cold-Induced Metabolic Adaptation · PMID 42274488 · 2 records
• Characterization of recombinant rat cathepsin B and nonglycosylated mutants expressed in yeast. New insights into the pH dependence of cathepsin B-catalyzed hydrolyses · PMID 1537854 · 43 records
• Characterization of recombinant xylitol dehydrogenase from Galactocandida mastotermitis expressed in Escherichia coli · PMID 12604239 · 12 records
• Characterization of retinaldehyde dehydrogenase 3 · PMID 16241904 · 9 records
• Characterization of RmlABCD Enzymes from Marine Bacteria and Efficient Synthesis of dTDP-L-Rhamnose · PMID 42197457 · 3 records
• Characterization of salt-regulated mannitol-1-phosphate dehydrogenase in the red alga Caloglossa continua · PMID 12972650 · 18 records
• Characterization of santalene synthases using an inorganic pyrophosphatase coupled colorimetric assay · PMID 29438678 · 5 records
• Characterization of short-chain dehydrogenase/reductase homologues of Escherichia coli (YdfG) and Saccharomyces cerevisiae (YMR226C) · PMID 12535615 · 17 records
• Characterization of site-directed mutants of residues R58, R59, D116, W340 and R372 in the active site of E. coli cystathionine beta-lyase · PMID 20014435 · 11 records
• Characterization of Streptococcus pneumoniae 5-enolpyruvylshikimate 3-phosphate synthase and its activation by univalent cations · PMID 10601870 · 16 records
• Characterization of structural and functional properties of human 17 beta-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesis · PMID 8994190 · 18 records
• Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases · PMID 12061798 · 14 records
• Characterization of successive ortho-methyl oxidation of the priority pollutant 2,4-xylenol by a Rieske oxygenase system in Pseudomonas putida NCIMB 9866 · PMID 42554493 · 5 records
• Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K · PMID 19420133 · 6 records
• Characterization of the 2',3' cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage lambda phosphatase · PMID 17986465 · 21 records
• Characterization of the acetate binding pocket in the Methanosarcina thermophila acetate kinase · PMID 15774882 · 27 records
• Characterization of the action of tyrosinase on resorcinols · PMID 27480027 · 4 records
• Characterization of the active-site residues asparagine 167 and lysine 161 of the IMP-1 metallo beta-lactamase · PMID 11287151 · 30 records
• Characterization of the activity and folding of the glutathione transferase from Escherichia coli and the roles of residues Cys(10) and His(106) · PMID 18778244 · 10 records
• Characterization of the acyl substrate binding pocket of acetyl-CoA synthetase · PMID 16981708 · 35 records
• Characterization of the alkaline laccase Ssl1 from Streptomyces sviceus with unusual properties discovered by genome mining · PMID 23285009 · 6 records
• Characterization of the arginine kinase isoforms in Caenorhabditis elegans · PMID 25981702 · 14 records
• Characterization of the ATP- and GTP-specific succinyl-CoA synthetases in pigeon. The enzymes incorporate the same alpha-subunit · PMID 9765290 · 12 records
• Characterization of the ATPase and unwinding activities of the yeast DEAD-box protein Has1p and the analysis of the roles of the conserved motifs · PMID 15718299 · 8 records
• Characterization of the AXDH gene and the encoded xylitol dehydrogenase from the dimorphic yeast Arxula adeninivorans · PMID 15803389 · 8 records
• Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies · PMID 11239085 · 12 records
• Characterization of the bga1-encoded glycoside hydrolase family 35 beta-galactosidase of Hypocrea jecorina with galacto-beta-D-galactanase activity · PMID 17381511 · 10 records
• Characterization of the bifunctional gamma-glutamate-cysteine ligase/glutathione synthetase (GshF) of Pasteurella multocida · PMID 16339152 · 7 records
• Characterization of the branched-chain amino acid aminotransferase enzyme family in tomato · PMID 20435740 · 42 records
• Characterization of the catalytic pathway for D-serine dehydratase. Evidence for variation of the rate-determining step with substrate structure · PMID 6406501 · 13 records
• Characterization of the cinnamoyl-CoA reductase (CCR) gene family in Populus tomentosa reveals the enzymatic active sites and evolution of CCR · PMID 27580618 · 15 records
• Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short- and medium-chain fatty acids and xenobiotic carboxylic acids · PMID 10434065 · 16 records
• Characterization of the cupin-type phosphoglucose isomerase from the hyperthermophilic archaeon Thermococcus litoralis · PMID 12560104 · 6 records
• Characterization of the E26H Mutant Schistosoma japonicum Glutathione S-Transferase · PMID 39748618 · 2 records
• Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors · PMID 12878203 · 7 records
• Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP · PMID 26813693 · 12 records
• Characterization of the enzymatic activity of the rhythmic human NADP(H) phosphatase, Nocturnin · PMID 41354364 · 5 records
• Characterization of the first described mutation of human red blood cell phosphoglycerate mutase · PMID 15949708 · 25 records
• Characterization of the functional role of allosteric site residue Asp102 in the regulatory mechanism of human mitochondrial NAD(P)+-dependent malate dehydrogenase (malic enzyme) · PMID 15989682 · 24 records
• Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts · PMID 15843146 · 8 records
• Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor · PMID 12788921 · 52 records
• Characterization of the hydrophobic substrate-binding site of the bacterial beta class glutathione transferase from Proteus mirabilis · PMID 20663851 · 18 records
• Characterization of the interaction between human cytochrome c and transfer RNA^phe · PMID 41788349 · 2 records
• Characterization of the interaction of Rhodobacter capsulatus cytochrome c peroxidase with charge reversal mutants of cytochrome c(2) · PMID 12573282 · 32 records
• Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis · PMID 20698828 · 5 records
• Characterization of the low-temperature activity of Sulfolobus tokodaii glucose-1-dehydrogenase mutants · PMID 24742629 · 17 records
• Characterization of the membrane quinoprotein glucose dehydrogenase from Escherichia coli and characterization of a site-directed mutant in which histidine-262 has been changed to tyrosine · PMID 10359647 · 18 records
• Characterization of the Methanomicrobial Archaeal RNase Zs for Processing the CCA-Containing tRNA Precursors · PMID 32982996 · 9 records
• Characterization of the multiple forms of duck lens delta-crystallin with endogenous argininosuccinate lyase activity · PMID 7944404 · 10 records
• Characterization of the N-acetyl-α-D-glucosaminyl l-malate synthase and deacetylase functions for bacillithiol biosynthesis in Bacillus anthracis · PMID 20799687 · 4 records
• Characterization of the NADP malic enzyme gene family in the facultative, single-cell C4 monocot Hydrilla verticillata · PMID 17638114 · 4 records
• Characterization of the naturally occurring oxacillinase of Acinetobacter baumannii · PMID 16189095 · 10 records
• Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain · PMID 18644957 · 20 records
• Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration · PMID 15561708 · 2 records
• Characterization of the novel class A β-Lactamase gene bla_KOB-1 in an Enterobacter isolate · PMID 41803721 · 5 records
• Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering · PMID 29328619 · 17 records
• Characterization of the Propham Biodegradation Pathway in Starkeya sp. Strain YW6 and Cloning of a Novel Amidase Gene mmH · PMID 30864436 · 5 records
• Characterization of the S289A,D mutants of yeast cystathionine beta-synthase · PMID 19264153 · 4 records
• Characterization of the Saccharomyces cerevisiae YMR318C (ADH6) gene product as a broad specificity NADPH-dependent alcohol dehydrogenase: relevance in aldehyde reduction · PMID 11742541 · 10 records
• Characterization of the substrate binding site of polyenoic fatty acid isomerase, a novel enzyme from the marine alga Ptilota filicina · PMID 9062129 · 8 records
• Characterization of the substrate scope of an alcohol dehydrogenase commonly used as methanol dehydrogenase · PMID 31006524 · 8 records
• Characterization of the substrate specificity of human carboxypeptidase A4 and implications for a role in extracellular peptide processing · PMID 20385563 · 27 records
• Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase · PMID 12416979 · 5 records
• Characterization of theanine-forming enzyme from Methylovorus mays no. 9 in respect to utilization of theanine production · PMID 17284842 · 8 records
• Characterization of thermophilic archaeal isopentenyl phosphate kinases · PMID 19928876 · 20 records
• Characterization of Thermotoga maritima glycerol dehydrogenase for the enzymatic production of dihydroxyacetone · PMID 24664447 · 32 records
• Characterization of Thiamin Phosphate Kinase in the Hyperthermophilic Archaeon Pyrobaculum calidifontis · PMID 26639844 · 6 records
• Characterization of three beta-galactoside phosphorylases from Clostridium phytofermentans: discovery of d-galactosyl-beta1->4-l-rhamnose phosphorylase · PMID 19491100 · 16 records
• Characterization of three essential residues in the conserved ATP-binding region of Epstein-Barr virus thymidine kinase · PMID 15779905 · 14 records
• Characterization of three fibrinogenolytic enzymes from Chinese green tree viper (Trimeresurus stejnegeri) venom · PMID 9637365 · 6 records
• Characterization of three isoenzymes of rat alcohol dehydrogenase. Tissue distribution and physical and enzymatic properties · PMID 3816781 · 45 records
• Characterization of three pyranose dehydrogenase isoforms from the litter-decomposing basidiomycete Leucoagaricus meleagris (syn. Agaricus meleagris) · PMID 27995309 · 34 records
• Characterization of Trypanosoma brucei gamma-glutamylcysteine synthetase, an essential enzyme in the biosynthesis of trypanothione (diglutathionylspermidine) · PMID 8663359 · 5 records
• Characterization of two aldo-keto reductases from Gluconobacter oxydans 621H capable of regio- and stereoselective alpha-ketocarbonyl reduction · PMID 20414648 · 6 records
• Characterization of two candidate flavone 8-O-methyltransferases suggests the existence of two potential routes to nevadensin in sweet basil · PMID 23747095 · 8 records
• Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family · PMID 15577209 · 90 records
• Characterization of two isozymes of coniferyl alcohol dehydrogenase from Streptomyces sp. NL15-2K · PMID 21897026 · 14 records
• Characterization of two M17 family members in Escherichia coli, Peptidase A and Peptidase B · PMID 20350528 · 16 records
• Characterization of two members among the five ADP-forming acyl coenzyme A (Acyl-CoA) synthetases reveals the presence of a 2-(Imidazol-4-yl)acetyl-CoA synthetase in Thermococcus kodakarensis · PMID 24163338 · 9 records
• Characterization of two novel aldo-keto reductases from Arabidopsis: expression patterns, broad substrate specificity, and an open active-site structure suggest a role in toxicant metabolism… · PMID 19616008 · 39 records
• Characterization of two novel alpha-glucosidases from Bifidobacterium breve UCC2003 · PMID 19114534 · 12 records
• Characterization of two transketolases encoded on the chromosome and the plasmid pBM19 of the facultative ribulose monophosphate cycle methylotroph Bacillus methanolicus · PMID 24405865 · 8 records
• Characterization of two β-decarboxylating dehydrogenases from Sulfolobus acidocaldarius · PMID 27590116 · 6 records
• Characterization of uronate dehydrogenases catalysing the initial step in an oxidative pathway · PMID 25884328 · 35 records
• Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2 · PMID 17181551 · 12 records
• Characterization of Ypr1p from Saccharomyces cerevisiae as a 2-methylbutyraldehyde reductase · PMID 12210903 · 11 records
• Characterization studies of glucose dehydrogenase · PMID 6641908 · 12 records
• Characterizing Family 1 Glycosyltransferases (GT1, UGT) by Reverse Glycosylation: Fast Determination of Acceptor Specificity, Donor Specificity, Hydrolysis, and Enzyme Stability · PMID 41835576 · 413 records
• Characterizing non-hydrolyzing Neisseria meningitidis serogroup A UDP-N-acetylglucosamine (UDP-GlcNAc) 2-epimerase using UDP-N-acetylmannosamine (UDP-ManNAc) and derivatives · PMID 26598987 · 5 records
• Charge stabilization and entropy reduction of central lysine residues in fructose-bisphosphate aldolase · PMID 19354220 · 8 records
• Chemical differentiation of three DMSP lyases from the marine Roseobacter group · PMID 28485454 · 26 records
• Chemical mechanism of the fructose-6-phosphate,2-kinase reaction from the pH dependence of kinetic parameters of site-directed mutants of active site basic residues · PMID 9220964 · 33 records
• Chemical modification and site-directed mutagenesis of cysteine residues in human placental S-adenosylhomocysteine hydrolase · PMID 8910410 · 21 records
• Chemical rescue by guanidine derivatives of an arginine-substituted site-directed mutant of Escherichia coli ornithine transcarbamylase · PMID 8973189 · 12 records
• Chemical synthesis of an indomethacin ester prodrug and its metabolic activation by human carboxylesterase 1 · PMID 29503023 · 8 records
• Chemistry and biology of deoxy-myo-inositol phosphates: stereospecificity of substrate interactions within an archaeal and a bacterial IMPase · PMID 15563150 · 12 records
• Chicken IDO2 and TDO2: Biochemical Characteristics and Regulatory Roles in Avian Tryptophan Metabolism and Inflammatory Response · PMID 42791731 · 12 records
• Chimeric allosteric citrate synthases: construction and properties of citrate synthases containing domains from two different enzymes · PMID 1524432 · 15 records
• Chimeric dihydrofolate reductases display properties of modularity and biophysical diversity · PMID 31095809 · 7 records
• Chlamydia trachomatis CT771 (nudH) is an asymmetric Ap4A hydrolase · PMID 24354275 · 6 records
• Choline acetyltransferase mutations cause myasthenic syndrome associated with episodic apnea in humans · PMID 11172068 · 16 records
• Choline-glycine betaine pathway confers a high level of osmotic tolerance in Escherichia coli · PMID 3512525 · 5 records
• Chorismate mutase-prephenate dehydratase from Escherichia coli. Study of catalytic and regulatory domains using genetically engineered proteins · PMID 9497350 · 11 records
• Chromogenic assay for the activity of sphingomyelinase from Bacillus cereus and its application to the enzymatic hydrolysis of lysophospholipids · PMID 15516713 · 9 records
• Chromohalobacter salixigens Uronate Dehydrogenase: Directed Evolution for Improved Thermal Stability and Mutant CsUDH-inc X-ray Crystal Structure · PMID 35462854 · 34 records
• Chymopapain A. Purification and investigation by covalent chromatography and characterization by two-protonic-state reactivity-probe kinetics, steady-state kinetics and resonance Raman spectroscopy… · PMID 3513753 · 27 records
• Cinnamic acid 4-hydroxylase from cell cultures of the hornwort Anthoceros agrestis · PMID 12721853 · 2 records
• Citramalate synthase yields a biosynthetic pathway for isoleucine and straight- and branched-chain ester formation in ripening apple fruit · PMID 33431667 · 12 records
• Citrate synthase from Cyanidioschyzon merolae exhibits high oxaloacetate and acetyl-CoA catalytic efficiency · PMID 36884198 · 8 records
• Citrobacter diversus ULA-27 beta-lactamases. Improved purification and general properties · PMID 3264152 · 24 records
• Clarification of cinnamoyl co-enzyme A reductase catalysis in monolignol biosynthesis of Aspen · PMID 15870094 · 4 records
• Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique · PMID 12852784 · 24 records
• Class C beta-lactamases operate at the diffusion limit for turnover of their preferred cephalosporin substrates · PMID 10390233 · 19 records
• Cleavage of bovine collagen I by neutrophil collagenase MMP-8. Effect of pH on the catalytic properties as compared to synthetic substrates · PMID 10749856 · 18 records
• Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases · PMID 12121577 · 9 records
• Cloning and characterisation of rosmarinic acid synthase from Melissa officinalis L · PMID 21354582 · 16 records
• Cloning and characterization of a leucyl aminopeptidase from three pathogenic Leishmania species · PMID 12006595 · 21 records
• Cloning and characterization of a low molecular weight prolyl 4-hydroxylase from Arabidopsis thaliana. Effective hydroxylation of proline-rich, collagen-like, and hypoxia-inducible transcription… · PMID 11976332 · 17 records
• Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and… · PMID 12407114 · 12 records
• Cloning and characterization of a new pH-stable alginate lyase with high salt tolerance from marine Vibrio sp. NJ-04 · PMID 29698759 · 3 records
• Cloning and characterization of a norbelladine 4'-O-methyltransferase involved in the biosynthesis of the Alzheimer's drug galanthamine in Narcissus sp. aff. pseudonarcissus · PMID 25061748 · 4 records
• Cloning and characterization of a novel aspartate/glutamate racemase from the acorn worm Saccoglossus kowalevskii · PMID 30902582 · 22 records
• Cloning and characterization of a novel CoA-ligase gene from Penicillium chrysogenum · PMID 21625874 · 27 records
• Cloning and characterization of a thermostable cellobiose dehydrogenase from Sporotrichum thermophile · PMID 10328816 · 12 records
• Cloning and characterization of aspartate-beta-semialdehyde dehydrogenase from Mycobacterium tuberculosis H37 Rv · PMID 15752328 · 4 records
• Cloning and characterization of dihydrofolate reductases from deep-sea bacteria · PMID 20040594 · 10 records
• Cloning and characterization of purple acid phosphatase phytases from wheat, barley, maize, and rice · PMID 21220762 · 16 records
• Cloning and characterization of Rhodotorula glutinis thymine hydroxylase · PMID 19341313 · 8 records
• Cloning and characterization of the Escherichia coli Heptosyltransferase III: Exploring substrate specificity in lipopolysaccharide core biosynthesis · PMID 25957775 · 5 records
• Cloning and characterization of the glucooligosaccharide catabolic pathway beta-glucan glucohydrolase and cellobiose phosphorylase in the marine hyperthermophile Thermotoga neapolitana · PMID 10960102 · 6 records
• Cloning and characterization of the l-ribose isomerase gene from Cellulomonas parahominis MB426 · PMID 23207370 · 12 records
• Cloning and characterization of the xyl1 gene, encoding an NADH-preferring xylose reductase from Candida parapsilosis, and its functional expression in Candida tropicalis · PMID 14532079 · 8 records
• Cloning and characterization of Thermotoga maritima beta-glucuronidase · PMID 16303119 · 16 records
• Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases · PMID 17690096 · 8 records
• Cloning and characterization of uronate dehydrogenases from two pseudomonads and Agrobacterium tumefaciens strain C58 · PMID 19060141 · 9 records
• Cloning and characterization of Vitis vinifera UDP-glucose:flavonoid 3-O-glucosyltransferase, a homologue of the enzyme encoded by the maize Bronze-1 locus that may primarily serve to glucosylate… · PMID 9535914 · 7 records
• Cloning and expressing a highly functional and substrate specific farnesoic acid o-methyltransferase from the Asian citrus psyllid (Diaphorina citri Kuwayama) · PMID 25893162 · 5 records
• Cloning and Expression of a Novel Leucine Dehydrogenase: Characterization and L-tert-Leucine Production · PMID 32296684 · 4 records
• Cloning and expression of Mycobacterium tuberculosis and Mycobacterium leprae dihydropteroate synthase in Escherichia coli · PMID 10542185 · 4 records
• Cloning and Expression of Phytase appA Gene from Shigella sp. CD2 in Pichia pastoris and Comparison of Properties with Recombinant Enzyme Expressed in E. coli · PMID 26808559 · 2 records
• Cloning and functional analysis of novel short-chain cis-prenyltransferases · PMID 18725204 · 8 records
• Cloning and functional characterization of a 4-coumarate CoA ligase from liverwort Plagiochasma appendiculatum · PMID 25593011 · 8 records
• Cloning and functional characterization of a peroxiredoxin 4 from yellowtail kingfish (Seriola lalandi) · PMID 20381631 · 8 records
• Cloning and functional characterization of the ambler class C beta-lactamase of Yersinia ruckeri · PMID 16553832 · 7 records
• Cloning and functional characterization of three flavonoid O-glucosyltransferase genes from the liverworts Marchantia emarginata and Marchantia paleacea · PMID 34166976 · 14 records
• Cloning and high-level production of a chitinase from Chromobacterium sp. and the role of conserved or nonconserved residues on its catalytic activity · PMID 17294188 · 7 records
• Cloning and molecular characterization of ant(9)-If: a novel aminoglycoside adenylyltransferase gene conferring resistance to spectinomycin · PMID 42022107 · 1 record
• Cloning and molecular characterization of tick kynurenine aminotransferase (HlKAT) from Haemaphysalis longicornis (Acari: Ixodidae) · PMID 19381689 · 5 records
• Cloning and overexpression of Lactobacillus helveticus D-lactate dehydrogenase gene in Escherichia coli · PMID 1396685 · 9 records
• Cloning of a cDNA encoding an aldehyde dehydrogenase and its expression in Escherichia coli. Recognition of retinal as substrate · PMID 8663198 · 12 records
• Cloning of a novel pyrethroid-hydrolyzing carboxylesterase gene from Sphingobium sp. strain JZ-1 and characterization of the gene product · PMID 19581484 · 12 records
• Cloning of three 2,3-dihydroxybiphenyl-1,2-dioxygenase genes from Achromobacter sp. BP3 and the analysis of their roles in the biodegradation of biphenyl · PMID 23948567 · 12 records
• Cloning, Baeyer-Villiger biooxidations, and structures of the camphor pathway 2-oxo-Δ(3)-4,5,5-trimethylcyclopentenylacetyl-coenzyme A monooxygenase of Pseudomonas putida ATCC 17453 · PMID 22267661 · 11 records
• Cloning, characterization and mutagenesis of Russell's viper venom L-amino acid oxidase: Insights into its catalytic mechanism · PMID 21802487 · 11 records
• Cloning, Characterization, and Computer-Aided Evolution of a Thermostable Laccase of the DUF152 Family From Klebsiella michiganensis · PMID 39950717 · 11 records
• Cloning, characterization, and engineering of fungal L-arabinitol dehydrogenases · PMID 20414651 · 22 records
• Cloning, expression and characterisation of CYP102A7, a self-sufficient P450 monooxygenase from Bacillus licheniformis · PMID 18483737 · 9 records
• Cloning, expression and characterization of 3-hydroxyisobutyrate dehydrogenase from Pseudomonas denitrificans ATCC 13867 · PMID 23658760 · 6 records
• Cloning, expression and characterization of a eukaryotic cycloalkanone monooxygenase from Cylindrocarpon radicicola ATCC 11011 · PMID 22075635 · 7 records
• Cloning, expression and characterization of a fast self-sufficient P450: CYP102A5 from Bacillus cereus · PMID 17945181 · 4 records
• Cloning, expression and characterization of an aryl-alcohol dehydrogenase from the white-rot fungus Phanerochaete chrysosporium strain BKM-F-1767 · PMID 22742413 · 14 records
• Cloning, expression and characterization of the proteinase from human herpesvirus 6 · PMID 8648756 · 15 records
• Cloning, expression and characterization of trehalose-6-phosphate phosphatase from a psychrotrophic bacterium, Arthrobacter strain A3 · PMID 22806197 · 5 records
• Cloning, expression and tissue distribution of a tetrameric form of pig carbonyl reductase · PMID 12604222 · 55 records
• Cloning, expression, and characterization of a cellobiose dehydrogenase from Thielavia terrestris induced under cellulose growth conditions · PMID 22484439 · 9 records
• Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene · PMID 11278832 · 3 records
• Cloning, expression, and characterization of a thermostable glucoamylase from Thermoanaerobacter tengcongensis MB4 · PMID 20155355 · 7 records
• Cloning, expression, and characterization of an aldehyde dehydrogenase from Escherichia coli K-12 that utilizes 3-Hydroxypropionaldehyde as a substrate · PMID 18668238 · 10 records
• Cloning, expression, and characterization of bacterial L-arabinose 1-dehydrogenase involved in an alternative pathway of L-arabinose metabolism · PMID 16326697 · 14 records
• Cloning, expression, and directed evolution of carbonyl reductase from Leifsonia xyli HS0904 with enhanced catalytic efficiency · PMID 24788330 · 6 records
• Cloning, expression, characterization, and biocatalytic investigation of the 4-hydroxyacetophenone monooxygenase from Pseudomonas putida JD1 · PMID 19251889 · 22 records
• Cloning, expression, purification, and properties of a putative plasma membrane hexokinase from Solanum chacoense · PMID 16376570 · 8 records
• Cloning, expression, site-directed mutagenesis and immunolocalization of phenylalanine ammonia-lyase in Bambusa oldhamii · PMID 21035152 · 10 records
• Cloning, functional expression, biochemical characterization, and structural analysis of a haloalkane dehalogenase from Plesiocystis pacifica SIR-1 · PMID 21603934 · 7 records
• Cloning, heterologous expression and biochemical characterization of plastidial sn-glycerol-3-phosphate acyltransferase from Helianthus annuus · PMID 25618244 · 4 records
• Cloning, heterologous expression, and characterization of the xylitol and L-arabitol dehydrogenase genes, Texdh and Telad, from the thermophilic fungus Talaromyces emersonii · PMID 20111899 · 7 records
• Cloning, heterologous expression, purification and characterization of M12 mutant of Aspergillus niger glucose oxidase in yeast Pichia pastoris KM71H · PMID 24122283 · 4 records
• Cloning, nucleotide sequences, and enzymatic properties of glucose dehydrogenase isozymes from Bacillus megaterium IAM1030 · PMID 1629157 · 8 records
• Cloning, overexpression, and properties of a new thermophilic and thermostable esterase with sequence similarity to hormone-sensitive lipase subfamily from the archaeon Archaeoglobus fulgidus · PMID 10620337 · 5 records
• Cloning, purification and characterization of an NAD-Dependent D-Arabitol dehydrogenase from acetic acid bacterium, Acetobacter suboxydans · PMID 19629658 · 6 records
• Cloning, purification and possible use of a Bacillus nitroreductase in biotechnological applications · PMID 42086690 · 4 records
• Cloning, purification, and characterization of thermostable hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis · PMID 14965769 · 12 records
• Cloning, sequence analysis, and expression in Escherichia coli of the gene encoding an alpha-amino acid ester hydrolase from Acetobacter turbidans · PMID 11772629 · 8 records
• Cloning, sequence analysis, expression, and inactivation of the Corynebacterium glutamicum icd gene encoding isocitrate dehydrogenase and biochemical characterization of the enzyme · PMID 7836312 · 3 records
• Cloning, sequencing and functional expression of cytosolic malate dehydrogenase from Taenia solium: Purification and characterization of the recombinant enzyme · PMID 21439955 · 4 records
• Cloning, sequencing, and heterologous expression of the murine peroxisomal flavoprotein, N1-acetylated polyamine oxidase · PMID 12660232 · 9 records
• Cloning, sequencing, heterologous expression, purification, and characterization of adenosylcobalamin-dependent D-ornithine aminomutase from Clostridium sticklandii · PMID 11577113 · 3 records
• Clonorchis sinensis: molecular cloning and functional expression of novel cytosolic malate dehydrogenase · PMID 15755419 · 4 records
• Close amino acid sequence relationship between the new plasmid-mediated extended-spectrum beta-lactamase MEN-1 and chromosomally encoded enzymes of Klebsiella oxytoca · PMID 1633193 · 10 records
• Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor · PMID 19122202 · 52 records
• Closely related form I ribulose bisphosphate carboxylase/oxygenase molecules that possess different CO2/O2 substrate specificities · PMID 9882445 · 11 records
• CMT-type beta-lactamase TEM-125, an emerging problem for extended-spectrum beta-lactamase detection · PMID 16801418 · 23 records
• Co-expression, purification, and characterization of an acidophilic and n-hexane-tolerant lipase with its foldase from Burkholderia gladioli Bsp-1 · PMID 41904273 · 7 records
• Co-occurrence of both L-asparaginase subtypes in Arabidopsis: At3g16150 encodes a K+-dependent L-asparaginase · PMID 16705405 · 5 records
• Cobalt starvation affects multiple cellular processes in Desulfofundulus kuznetsovii TPOSR during alcohol oxidation · PMID 42690966 · 5 records
• Cobamides and ribonucleotide reduction. V. A kinetic study of the ribonucleoside triphosphate reductase of Lactobacillus leichmannii · PMID 4381877 · 15 records
• Codeinone reductase isoforms with differential stability, efficiency and product selectivity in opium poppy · PMID 29779229 · 8 records
• Coenzyme A disulfide reductase, the primary low molecular weight disulfide reductase from Staphylococcus aureus. Purification and characterization of the native enzyme · PMID 9488707 · 5 records
• Coenzyme A-acylating aldehyde dehydrogenase from Clostridium beijerinckii NRRL B592 · PMID 2275527 · 14 records
• Coenzyme Engineering of a Hyperthermophilic 6-Phosphogluconate Dehydrogenase from NADP⁺ to NAD⁺ with Its Application to Biobatteries · PMID 27805055 · 9 records
• Coenzyme site-directed mutants of photosynthetic A4-GAPDH show selectively reduced NADPH-dependent catalysis, similar to regulatory AB-GAPDH inhibited by oxidized thioredoxin · PMID 15236965 · 20 records
• Coexistence of bacterial leucyl-tRNA synthetases with archaeal tRNA binding domains that distinguish tRNA(Leu) in the archaeal mode · PMID 24500203 · 19 records
• Coexisting kinetically distinguishable forms of dialkylglycine decarboxylase engendered by alkali metal ions · PMID 9548963 · 4 records
• Cofactor binding triggers a molecular switch to allosterically activate human UDP-α-D-glucose 6-dehydrogenase · PMID 23106432 · 4 records
• Cofactor engineering for improved production of 2,4-dihydroxybutyric acid via the synthetic homoserine pathway · PMID 40051839 · 6 records
• Cofactor Specificity of the Bifunctional Alcohol and Aldehyde Dehydrogenase (AdhE) in Wild-Type and Mutant Clostridium thermocellum and Thermoanaerobacterium saccharolyticum · PMID 26013492 · 10 records
• Cold adaptation of xylose isomerase from Thermus thermophilus through random PCR mutagenesis. Gene cloning and protein characterization · PMID 11784309 · 8 records
• Cold-active alkaline phosphatase is irreversibly transformed into an inactive dimer by low urea concentrations · PMID 27043172 · 9 records
• Cold-active citrate synthase: mutagenesis of active-site residues · PMID 11707611 · 22 records
• Cold-adaptation mechanism of mutant enzymes of 3-isopropylmalate dehydrogenase from Thermus thermophilus · PMID 12082165 · 28 records
• Combination of phenylpyruvic acid (PPA) pathway engineering and molecular engineering of L-amino acid deaminase improves PPA production with an Escherichia coli whole-cell biocatalyst · PMID 26552798 · 9 records
• Combinatorial engineering of dextransucrase specificity · PMID 24204991 · 7 records
• Combinatorial pathway enzyme engineering and host engineering overcomes pyruvate overflow and enhances overproduction of N-acetylglucosamine in Bacillus subtilis · PMID 30609921 · 2 records
• Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase · PMID 19245203 · 18 records
• Combining mutagenesis on Glu281 of prenyltransferase NovQ and metabolic engineering strategies for the increased prenylated activity towards menadione · PMID 32125480 · 10 records
• Common-type acylphosphatase: steady-state kinetics and leaving-group dependence · PMID 9355750 · 7 records
• Comparative active-site mutation study of human and Caenorhabditis elegans thymidine kinase 1 · PMID 22385435 · 24 records
• Comparative analyses of hairpin substrate recognition by Escherichia coli and Bacillus subtilis ribonuclease P ribozymes · PMID 12951523 · 6 records
• Comparative Analysis of Kinetic Parameters of Sustainable Branched Esters Obtained from Lauric Acid · PMID 41726757 · 8 records
• Comparative analysis of ribosome-associated adenosinetriphosphatase (ATPase) from pig liver and the ATPase of elongation factor 3 from Saccharomyces cerevisiae · PMID 7957240 · 10 records
• Comparative analysis of two glyceraldehyde-3-phosphate dehydrogenases from a thermoacidophilic archaeon, Sulfolobus tokodaii · PMID 22841742 · 20 records
• Comparative biochemical and functional properties of two leucine aminopeptidases of Clonorchis sinensis · PMID 22155540 · 16 records
• Comparative biochemical and functional studies of family I soluble inorganic pyrophosphatases from photosynthetic bacteria · PMID 17635582 · 7 records
• Comparative characterization of Aedes 3-hydroxykynurenine transaminase/alanine glyoxylate transaminase and Drosophila serine pyruvate aminotransferase · PMID 12220660 · 18 records
• Comparative characterization of nine novel GH51, GH54 and GH62 α-l-arabinofuranosidases from Penicillium subrubescens · PMID 35014696 · 9 records
• Comparative characterization of three D-aspartate oxidases and one D-amino acid oxidase from Caenorhabditis elegans · PMID 20564561 · 22 records
• Comparative Characterization of Three Homologous Glutathione Transferases from the Weed Lolium perenne · PMID 39594000 · 21 records
• Comparative enzymatic properties of GapB-encoded erythrose-4-phosphate dehydrogenase of Escherichia coli and phosphorylating glyceraldehyde-3-phosphate dehydrogenase · PMID 9182530 · 33 records
• Comparative enzymology of 11 beta -hydroxysteroid dehydrogenase type 1 from glucocorticoid resistant (Guinea pig) versus sensitive (human) species · PMID 12397058 · 10 records
• Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids · PMID 16787387 · 8 records
• Comparative functional characterization of eugenol synthase from four different Ocimum species: Implications on eugenol accumulation · PMID 27519164 · 7 records
• Comparative glandular trichome transcriptome-based gene characterization reveals reasons for differential (-)-menthol biosynthesis in Mentha species · PMID 28188954 · 12 records
• Comparative insight into the roles of the non active-site residues E169 and N173 in imparting the beta-lactamase activity of CTX-M-15 · PMID 35175332 · 8 records
• Comparative kinetic properties of alpha, beta and psi forms of trypsin · PMID 4472038 · 17 records
• Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2 · PMID 15316017 · 23 records
• Comparative structural analysis and kinetic properties of lactate dehydrogenases from the four species of human malarial parasites · PMID 15147206 · 20 records
• Comparative structural analysis and substrate specificity engineering of the hyperthermostable beta-glucosidase CelB from Pyrococcus furiosus · PMID 10819960 · 16 records
• Comparative structural and enzymatic studies on Salmonella typhimurium diaminopropionate ammonia lyase reveal its unique features · PMID 29294403 · 8 records
• Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase · PMID 31141475 · 10 records
• Comparative studies of lactic acid dehydrogenases in lactic acid bacteria. I. Purification and kinetics of the allosteric L-lactic acid dehydrogenase from Lactobacillus casei ssp. casei and… · PMID 14601 · 22 records
• Comparative study of catalase-peroxidases (KatGs) · PMID 18178143 · 28 records
• Comparative study of Leishmania mexicana and Trypanosoma brucei NAD-dependent glycerol-3-phosphate dehydrogenase · PMID 10743613 · 8 records
• Comparative substrate specificity analysis of recombinant human cathepsin V and cathepsin L · PMID 15369827 · 144 records
• Compared action of neutrophil proteinase 3 and elastase on model substrates. Favorable effect of S'-P' interactions on proteinase 3 catalysts · PMID 12538645 · 51 records
• Comparing Ligninolytic Capabilities of Bacterial and Fungal Dye-Decolorizing Peroxidases and Class-II Peroxidase-Catalases · PMID 33807844 · 17 records
• Comparison between procaine and isocarboxazid metabolism in vitro by a liver microsomal amidase-esterase · PMID 8 · 2 records
• Comparison of crotoxin isoforms reveals that stability of the complex plays a major role in its pharmacological action · PMID 8513799 · 12 records
• Comparison of different microbial laccases as tools for industrial uses · PMID 26844639 · 32 records
• Comparison of glyoxalase I purified from yeast (Saccharomyces cerevisiae) with the enzyme from mammalian sources · PMID 393249 · 8 records
• Comparison of human and porcine tissue kallikrein substrate specificities · PMID 10615005 · 18 records
• Comparison of kinetic constants of creatine kinase isoforms · PMID 16451808 · 22 records
• Comparison of skin esterase activities from different species · PMID 16779705 · 40 records
• Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis · PMID 19636684 · 15 records
• Comparison of the HIV-1 and HIV-2 proteinases using oligopeptide substrates representing cleavage sites in Gag and Gag-Pol polyproteins · PMID 2015912 · 25 records
• Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase · PMID 25030770 · 8 records
• Comparison of the three rat GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferases FTA, FTB and FTC · PMID 11179967 · 10 records
• Comparison of three tannases cloned from closely related lactobacillus species: L. Plantarum, L. Paraplantarum, and L. Pentosus · PMID 24708557 · 24 records
• Comparison of two metal-dependent pyruvate aldolases related by convergent evolution: substrate specificity, kinetic mechanism, and substrate channeling · PMID 20364820 · 19 records
• Comparison of two models of surface display of xylose reductase in the Saccharomyces cerevisiae cell wall · PMID 30686349 · 18 records
• Comparison of Type 1 D-3-phosphoglycerate dehydrogenases reveals unique regulation in pathogenic Mycobacteria · PMID 25698123 · 14 records
• Complementary deoxyribonucleic acid cloning and enzymatic characterization of a novel 17beta/3alpha-hydroxysteroid/retinoid short chain dehydrogenase/reductase · PMID 10537158 · 1 record
• Complete oxidation of hydroxymethylfurfural to furandicarboxylic acid by aryl-alcohol oxidase · PMID 31528205 · 38 records
• Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics · PMID 11923312 · 6 records
• Complete replacement set of amino acids at the C-terminus of thymidylate synthase: quantitative structure-activity relationship of mutants of an enzyme · PMID 1627545 · 46 records
• Complete reversal of coenzyme specificity of xylitol dehydrogenase and increase of thermostability by the introduction of structural zinc · PMID 15623532 · 49 records
• Composite active site of chondroitin lyase ABC accepting both epimers of uronic acid · PMID 18227125 · 16 records
• Comprehensive analysis of cytosolic Nudix hydrolases in Arabidopsis thaliana · PMID 15878881 · 11 records
• Comprehensive biochemical, molecular and structural characterization of subtilisin with fibrinolytic potential in bioprocessing · PMID 40117024 · 2 records
• Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk · PMID 22942235 · 14 records
• Comprehensive investigation of a dye-decolorizing peroxidase and a manganese peroxidase from Irpex lacteus F17, a lignin-degrading basidiomycete · PMID 30019324 · 15 records
• Comprehensive kinetic and substrate specificity analysis of an arylsulfatase from Helix pomatia using mass spectrometry · PMID 30738652 · 11 records
• Comprehensive screening strategy coupled with structure-guided engineering of l-threonine aldolase from Pseudomonas putida for enhanced catalytic efficiency towards… · PMID 36793440 · 14 records
• Compromised catalysis and potential folding defects in in vitro studies of missense mutants associated with hereditary phosphoglucomutase 1 deficiency · PMID 25288802 · 10 records
• Computation-Guided Tunnel Engineering Enhances O₂ Transport and H₂O₂ Resistance of Fe(II)/α-Ketoglutarate-Dependent Dioxygenases · PMID 42405750 · 6 records
• Computational and experimental engineering of a Pleurotus citrinopileatus lipases: Structural insights and functional optimization to adapt the hydrolytic profile for cheese… · PMID 41704880 · 12 records
• Computational and experimental insights into the mechanism of substrate recognition and feedback inhibition of protoporphyrinogen oxidase · PMID 23935953 · 11 records
• Computational design and experimental evaluation of glycosyltransferase mutants: engineering of a blood type B galactosyltransferase with enhanced glucosyltransferase activity · PMID 17138593 · 6 records
• Computational Design of a Thermo-Acidostable Endo-Polygalacturonase for Efficient Juice Extraction · PMID 41897700 · 2 records
• Computational design of Bacillus licheniformis RN-01 levansucrase for control of the chain length of levan-type fructooligosaccharides · PMID 31437510 · 43 records
• Computational Design of CYP102A1 Variants for Biosynthesis of a Next-Generation Antiplatelet Drug DT-678 · PMID 41791881 · 5 records
• Computational Design of Enantiocomplementary Epoxide Hydrolases for Asymmetric Synthesis of Aliphatic and Aromatic Diols · PMID 31961471 · 12 records
• Computational design of enhanced detoxification activity of a zearalenone lactonase from Clonostachys rosea in acidic medium · PMID 35527979 · 17 records
• Computational design of oligosaccharide producing levansucrase from Bacillus licheniformis RN-01 to improve its thermostability for production of levan-type fructooligosaccharides from sucrose · PMID 32439436 · 8 records
• Computational evolution of poly(U) polymerase for efficient and controlled RNA oligonucleotide synthesis · PMID 41603735 · 32 records
• Computer-Aided Virtual Saturation Mutagenesis Improves the Lignocellulose-Degrading Performance of an Aspergillus niger LPMO · PMID 42354146 · 3 records
• Computer-directed rational engineering of dioxygenase TcsAB for triclosan biodegradation under cold conditions · PMID 40042274 · 2 records
• Conferral of allostery to Thermus sp. GH5 methylglyoxal synthase by a single mutation · PMID 23038673 · 15 records
• Conflicting requirements of Plasmodium falciparum dihydrofolate reductase mutations conferring resistance to pyrimethamine-WR99210 combination · PMID 17875995 · 16 records
• Conformational changes and substrate recognition in Pseudomonas aeruginosa D-arginine dehydrogenase · PMID 20809650 · 16 records
• Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme · PMID 23030629 · 41 records
• Conformational changes in the di-domain structure of Arabidopsis phosphoethanolamine methyltransferase leads to active-site formation · PMID 29084845 · 15 records
• Conformational changes involving ammonia tunnel formation and allosteric control in GMP synthetase · PMID 24434004 · 23 records
• Conformational Dynamics and Catalytic Backups in a Hyper-thermostable Engineered Archaeal Protein Tyrosine Phosphatase · PMID 41614192 · 5 records
• Conformational dynamics of the active site loop of S-adenosylmethionine synthetase illuminated by site-directed spin labeling · PMID 12831838 · 10 records
• Conformational flexibility associated with remote residues regulates the kinetic properties of glutamate dehydrogenase · PMID 39981924 · 8 records
• Conformational flexibility of PEP mutase · PMID 15078090 · 4 records
• Conservation and Role of Electrostatics in Thymidylate Synthase · PMID 26612036 · 4 records
• Conservation of mechanism in three chorismate-utilizing enzymes · PMID 14982443 · 9 records
• Conservative mutations of glutamine-125 in herpes simplex virus type 1 thymidine kinase result in a ganciclovir kinase with minimal deoxypyrimidine kinase activities · PMID 10747801 · 7 records
• Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis · PMID 14756557 · 18 records
• Conserved arginine-516 of Penicillium amagasakiense glucose oxidase is essential for the efficient binding of beta-D-glucose · PMID 10749686 · 9 records
• Conserved cysteine residues of histidinol dehydrogenase are not involved in catalysis. Novel chemistry required for enzymatic aldehyde oxidation · PMID 8314784 · 12 records
• Conserved residues in the mechanism of the E. coli Class II FBP-aldolase · PMID 9878448 · 18 records
• Considerations Regarding Activity Determinants of Fungal Polyphenol Oxidases Based on Mutational and Structural Studies · PMID 33741634 · 35 records
• Construction and characterization of mutant water-soluble PQQ glucose dehydrogenases with altered K(m) values--site-directed mutagenesis studies on the putative active site · PMID 10544015 · 32 records
• Construction of a synthetic metabolic pathway for biosynthesis of the non-natural methionine precursor 2,4-dihydroxybutyric acid · PMID 28631755 · 49 records
• Construction of cellobiose phosphorylase variants with broadened acceptor specificity towards anomerically substituted glucosides · PMID 20517986 · 7 records
• Continuous assays for meprin alpha and beta using prolyl tripeptidyl aminopeptidase (PtP) from Porphyromonas gingivalis · PMID 30098994 · 5 records
• Continuous Directed Evolution of a Short-Lived Plant Histidinol Dehydrogenase · PMID 41688052 · 7 records
• Contrasting in vitro and in vivo methanol oxidation activities of lanthanide-dependent alcohol dehydrogenases XoxF1 and ExaF from Methylobacterium extorquens AM1 · PMID 30862918 · 5 records
• Contrasting pH optima of β-lactamases CTX-M and CMY influence Escherichia coli fitness and resistance ecology · PMID 41457317 · 10 records
• Contribution of a low-barrier hydrogen bond to catalysis is not significant in ketosteroid isomerase · PMID 25947291 · 2 records
• Contribution of an imidazole-indole stack to high catalytic potency of a lysine-specific serine protease, Achromobacter protease I · PMID 11820934 · 35 records
• Contribution of CoA ligases to benzenoid biosynthesis in petunia flowers · PMID 22649270 · 10 records
• Contribution of the 7β-hydroxysteroid dehydrogenase from Ruminococcus gnavus N53 to ursodeoxycholic acid formation in the human colon · PMID 23729502 · 2 records
• Contribution of the two domains of E. coli 5'-nucleotidase to substrate specificity and catalysis · PMID 23333297 · 8 records
• Contribution to catalysis of ornithine binding residues in ornithine N5-monooxygenase · PMID 26375201 · 12 records
• Contributions of unique active site residues of eukaryotic UDP-galactopyranose mutases to substrate recognition and active site dynamics · PMID 25412209 · 12 records
• Control activity of yeast geranylgeranyl diphosphate synthase from dimer interface through H-bonds and hydrophobic interaction · PMID 23534508 · 22 records
• Control of glucose utilization in working perfused rat heart · PMID 7929251 · 25 records
• Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium · PMID 17927213 · 12 records
• Control of the NADPH supply and GSH recycling for oxidative stress management in hepatoma and liver mitochondria · PMID 30053395 · 26 records
• Controlling the regioselectivity and stereospecificity of FAD-dependent polyamine oxidases with the use of amine-attached guide molecules as conformational modulators · PMID 30006473 · 17 records
• Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase · PMID 14734549 · 5 records
• Convergent evolution in the BAHD family of acyl transferases: identification and characterization of anthocyanin acyl transferases from Arabidopsis thaliana · PMID 17425720 · 26 records
• Convergent Evolution of a Promiscuous 3-Hydroxypropionyl-CoA Dehydratase/Crotonyl-CoA Hydratase in Crenarchaeota and Thaumarchaeota · PMID 33472982 · 24 records
• Convergent Mechanistic Features between the Structurally Diverse N- and O-Methyltransferases: Glycine N-Methyltransferase and Catechol O-Methyltransferase · PMID 27355841 · 14 records
• Conversion of 4-hydroxybutyrate to acetyl coenzyme A and its anapleurosis in the Metallosphaera sedula 3-hydroxypropionate/4-hydroxybutyrate carbon fixation pathway · PMID 24532060 · 4 records
• Conversion of a glutamate dehydrogenase into methionine/norleucine dehydrogenase by site-directed mutagenesis · PMID 11722565 · 36 records
• Conversion of cysteine to 3-mercaptopyruvic acid by bacterial aminotransferases · PMID 28193330 · 6 records
• Conversion of feedback regulation in aspartate kinase by domain exchange · PMID 15033471 · 6 records
• Conversion of human steroid 5β-reductase (AKR1D1) into 3β-hydroxysteroid dehydrogenase by single point mutation E120H: example of perfect enzyme engineering · PMID 22437839 · 10 records
• Conversion of Inactive Non-Pro1 Tautomerase Superfamily Members into Active Tautomerases: Analysis of the Pro1 Mutants · PMID 39914393 · 14 records
• Conversion of L-lactate oxidase to a long chain alpha-hydroxyacid oxidase by site-directed mutagenesis of alanine 95 to glycine · PMID 8910450 · 16 records
• Conversion of methylamine dehydrogenase to a long-chain amine dehydrogenase by mutagenesis of a single residue · PMID 10985763 · 22 records
• Conversion of methylglyoxal to acetol by Escherichia coli aldo-keto reductases · PMID 16077126 · 4 records
• Cooperation between β-galactosidase and an isoprimeverose-producing oligoxyloglucan hydrolase is key for xyloglucan degradation in Aspergillus oryzae · PMID 30980597 · 4 records
• Cooperative effect of two surface amino acid mutations (Q252L and E170K) in glucose dehydrogenase from Bacillus megaterium IWG3 on stabilization of its oligomeric state · PMID 15933031 · 12 records
• Copper Coordination to the Prion Fragment (95-126): Implications for Neurodegenerative Diseases · PMID 42196171 · 6 records
• Copper Radical Oxidases Contribute to Virulence in Sclerotinia sclerotiorum · PMID 42796654 · 6 records
• Copy-DNA cloning and characterisation of a potato alpha-glucosidase: expression in Escherichia coli and effects of down-regulation in transgenic potato · PMID 11469591 · 7 records
• Correction to "Fortification of FeS Clusters Reshapes Anaerobic CO Dehydrogenase into an Air-Viable Enzyme Through Multilayered Sealing of O₂ Tunnels" · PMID 41287407 · 16 records
• Correlated Mutation in the Evolution of Catalysis in Uracil DNA Glycosylase Superfamily · PMID 28397787 · 10 records
• Correlation between dissociation and catalysis of SARS-CoV main protease · PMID 18275836 · 24 records
• Correlation between the T1 copper reduction potential and catalytic activity of a small laccase · PMID 31536948 · 14 records
• Correlation of structure and function in the human hotdog-fold enzyme hTHEM4 · PMID 22871024 · 8 records
• Correlations of inhibitor kinetics for Pneumocystis jirovecii and human dihydrofolate reductase with structural data for human active site mutant enzyme complexes · PMID 19196009 · 20 records
• Cosubstrate and allosteric modifier activities of structural analogues of NAD and ADP for NAD-specific isocitrate dehydrogenase from bovine heart · PMID 223632 · 1 record
• Coupling effects of distal loops on structural stability and enzymatic activity of Escherichia coli dihydrofolate reductase revealed by deletion mutants · PMID 20045086 · 11 records
• Covalent immobilization of Lepidium draba peroxidase on chitosan-coated magnetic nanoparticles and its application in glucose biosensing · PMID 41634276 · 4 records
• Covalent modification of reduced flavin mononucleotide in type-2 isopentenyl diphosphate isomerase by active-site-directed inhibitors · PMID 22158896 · 6 records
• Cowchock syndrome is associated with a mutation in apoptosis-inducing factor · PMID 23217327 · 21 records
• Creatine kinase: a role for arginine-95 in creatine binding and active site organization · PMID 11295435 · 8 records
• Creatine kinase: the reactive cysteine is required for synergism but is nonessential for catalysis · PMID 8334132 · 25 records
• Creating a non-native bio-amidation activity in asparagine synthetase via biosensor-guided directed evolution for the synthesis of (S)-2-aminobutyramide · PMID 42683046 · 2 records
• Creating lactose phosphorylase enzymes by directed evolution of cellobiose phosphorylase · PMID 19487233 · 8 records
• CreSAMT1 is mainly responsible for the biosynthesis of characteristic aroma compound dimethyl anthranilate in Citrus reticulata 'Chachiensis' · PMID 41810387 · 8 records
• CRISPR/Cas9 editing of two adenine phosphoribosyl transferase coding genes reveals the functional specialization of adenine salvage proteins in common bean · PMID 39387692 · 6 records
• Critical amino acids in phosphodiesterase-5 catalytic site that provide for high-affinity interaction with cyclic guanosine monophosphate and inhibitors · PMID 17979301 · 9 records
• Critical determinants for substrate recognition and catalysis in the M. tuberculosis class II AP-endonuclease/3'-5' exonuclease III · PMID 25748880 · 8 records
• Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors · PMID 22238126 · 8 records
• Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase · PMID 14592457 · 28 records
• Critical role of Ca2+ ions in the reaction mechanism of Euphorbia characias peroxidase · PMID 12873152 · 6 records
• Critical role of Lys212 and Tyr140 in porcine NADP-dependent isocitrate dehydrogenase · PMID 14512428 · 16 records
• Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes · PMID 15750346 · 20 records
• Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases · PMID 19860471 · 59 records
• Critical roles of conserved carboxylic acid residues in pigeon cytosolic NADP+-dependent malic enzyme · PMID 16889632 · 23 records
• Critical Sites of DNA Backbone Integrity for Damaged Base Removal by Formamidopyrimidine-DNA Glycosylase · PMID 31120733 · 22 records
• Cross-functionalities of Bacillus deacetylases involved in bacillithiol biosynthesis and bacillithiol-S-conjugate detoxification pathways · PMID 23758290 · 16 records
• Cross-Species Analysis of Protein Dynamics Associated with Hydride and Proton Transfer in the Catalytic Cycle of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase · PMID 26807652 · 20 records
• Cross-talk between thiamin diphosphate binding and phosphorylation loop conformation in human branched-chain alpha-keto acid decarboxylase/dehydrogenase · PMID 15166214 · 22 records
• Crucial role of conserved lysine 277 in the fidelity of tRNA aminoacylation by Escherichia coli valyl-tRNA synthetase · PMID 12475234 · 11 records
• Crucial role of the C-terminal domain of Mycobacterium tuberculosis leucyl-tRNA synthetase in aminoacylation and editing · PMID 23268443 · 13 records
• Cryo-EM Structure of Recombinantly Expressed hUGDH Unveils a Hidden, Alternative Allosteric Inhibitor · PMID 39680853 · 8 records
• CryoEM and crystal structure analyses reveal the indirect role played by Trp89 in glutamate dehydrogenase enzymatic reactions · PMID 39891504 · 2 records
• Cryoenzymic studies on yeast 3-phosphoglycerate kinase. Attempt to obtain the kinetics of the hinge-bending motion · PMID 9154937 · 10 records
• Crystal Structure and Biochemical Characterization of Ketol-Acid Reductoisomerase from Corynebacterium glutamicum · PMID 31298526 · 3 records
• Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases · PMID 27816563 · 11 records
• Crystal structure and biochemical studies of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase · PMID 24657441 · 26 records
• Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1 · PMID 19054767 · 12 records
• Crystal structure and computational analyses provide insights into the catalytic mechanism of 2,4-diacetylphloroglucinol hydrolase PhlG from Pseudomonas fluorescens · PMID 20018877 · 9 records
• Crystal structure and enzymatic properties of chalcone isomerase from the Antarctic vascular plant Deschampsia antarctica Desv · PMID 29394293 · 19 records
• Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis · PMID 19776021 · 18 records
• Crystal structure and functional assignment of YfaU, a metal ion dependent class II aldolase from Escherichia coli K12 · PMID 18754683 · 6 records
• Crystal structure and functional characterization of an isoaspartyl dipeptidase (CpsIadA) from Colwellia psychrerythraea strain 34H · PMID 28723955 · 8 records
• Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic β-glucosidase Td2F2 · PMID 27092463 · 48 records
• Crystal structure and identification of amino acid residues for catalysis and binding of GH3 AnBX β-xylosidase from Aspergillus niger · PMID 36877249 · 51 records
• Crystal Structure and Identification of Two Key Amino Acids Involved in AI-2 Production and Biofilm Formation in Streptococcus suis LuxS · PMID 26484864 · 5 records
• Crystal structure and immunogenicity of the class C acid phosphatase from Pasteurella multocida · PMID 21371420 · 5 records
• Crystal structure and kinetics identify Escherichia coli YdcW gene product as a medium-chain aldehyde dehydrogenase · PMID 15381418 · 58 records
• Crystal Structure and Mutational Analysis of Isomalto-dextranase, a Member of Glycoside Hydrolase Family 27 · PMID 26330557 · 8 records
• Crystal structure and pH-dependent allosteric regulation of human β-ureidopropionase, an enzyme involved in anticancer drug metabolism · PMID 29976570 · 10 records
• Crystal structure and tartrate inhibition of Legionella pneumophila histidine acid phosphatase · PMID 26380880 · 3 records
• Crystal structure and thermodynamic and kinetic stability of metagenome-derived LC-cutinase · PMID 24593046 · 9 records
• Crystal structure at 1.8 A resolution and identification of active site residues of Sulfolobus solfataricus peptidyl-tRNA hydrolase · PMID 15766258 · 11 records
• Crystal Structure of 4-Hydroxyphenylpyruvate Dioxygenase in Complex with Substrate Reveals a New Starting Point for Herbicide Discovery · PMID 31549053 · 7 records
• Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity · PMID 18566346 · 10 records
• Crystal structure of a cold-adapted class C beta-lactamase · PMID 18312599 · 8 records
• Crystal structure of a hyperthermophilic archaeal acylphosphatase from Pyrococcus horikoshii--structural insights into enzymatic catalysis, thermostability, and dimerization · PMID 15779887 · 5 records
• Crystal structure of a new type of NADPH-dependent quinone oxidoreductase (QOR2) from Escherichia coli · PMID 18455185 · 10 records
• Crystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activity · PMID 22997138 · 8 records
• Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution · PMID 21308848 · 15 records
• Crystal Structure of a Thermostable Alanine Racemase from Thermoanaerobacter tengcongensis MB4 Reveals the Role of Gln360 in Substrate Selection · PMID 26218070 · 12 records
• Crystal structure of a β1,3-Glucosyltransferase reveals an unusual substrate recognition by a two-domain GT-A fold glycosyltransferase · PMID 42575440 · 16 records
• Crystal structure of an Exo-1,5-α-L-arabinofuranosidase from Streptomyces avermitilis provides insights into the mechanism of substrate discrimination between exo- and endo-type enzymes in… · PMID 20739278 · 17 records
• Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection · PMID 20527960 · 7 records
• Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry · PMID 26859324 · 6 records
• Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism · PMID 19213731 · 6 records
• Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis · PMID 31548418 · 5 records
• Crystal structure of CotA laccase complexed with 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) at a novel binding site · PMID 27050268 · 16 records
• Crystal structure of DmdD, a crotonase superfamily enzyme that catalyzes the hydration and hydrolysis of methylthioacryloyl-CoA · PMID 23704947 · 7 records
• Crystal structure of E.coli alcohol dehydrogenase YqhD: evidence of a covalently modified NADP coenzyme · PMID 15327949 · 11 records
• Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling · PMID 23027977 · 4 records
• Crystal structure of Escherichia coli diaminopropionate ammonia-lyase reveals mechanism of enzyme activation and catalysis · PMID 22505717 · 7 records
• Crystal structure of Escherichia coli enterobactin-specific isochorismate synthase (EntC) bound to its reaction product isochorismate: implications for the enzyme mechanism and differential activity… · PMID 20079748 · 8 records
• Crystal structure of Escherichia coli ketopantoate reductase in a ternary complex with NADP+ and pantoate bound: substrate recognition, conformational change, and cooperativity · PMID 17229734 · 14 records
• Crystal structure of Escherichia coli xanthine phosphoribosyltransferase · PMID 9100006 · 4 records
• Crystal structure of extended-spectrum beta-lactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion · PMID 12962487 · 20 records
• Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism · PMID 20620151 · 12 records
• Crystal structure of group A streptococcus Mac-1: insight into dimer-mediated specificity for recognition of human IgG · PMID 16472742 · 11 records
• Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD⁺ and retinoic acid · PMID 27759097 · 6 records
• Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity · PMID 15595823 · 4 records
• Crystal structure of human pyrroline-5-carboxylate reductase · PMID 16730026 · 6 records
• Crystal structure of human thioesterase superfamily member 2 · PMID 16934754 · 15 records
• Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase · PMID 11285217 · 9 records
• Crystal structure of l-rhamnose 1-dehydrogenase involved in the nonphosphorylative pathway of l-rhamnose metabolism in bacteria · PMID 33482017 · 22 records
• Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition · PMID 10360941 · 4 records
• Crystal structure of Medicago truncatula UGT85H2--insights into the structural basis of a multifunctional (iso)flavonoid glycosyltransferase · PMID 17553523 · 6 records
• Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity · PMID 16460003 · 5 records
• Crystal structure of NADP(H)-dependent 1,5-anhydro-D-fructose reductase from Sinorhizobium morelense at 2.2 A resolution: construction of a NADH-accepting mutant and its application in rare sugar… · PMID 16906761 · 24 records
• Crystal structure of Plasmodium falciparum adenosine deaminase reveals a novel binding pocket for inosine · PMID 31002765 · 22 records
• Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 · PMID 17989071 · 6 records
• Crystal structure of pyridoxine 4-oxidase from Mesorhizobium loti · PMID 23501672 · 3 records
• Crystal structure of reaction intermediates in pyruvate class II aldolase: substrate cleavage, enolate stabilization, and substrate specificity · PMID 22908224 · 5 records
• Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway · PMID 27935959 · 28 records
• Crystal structure of the 2-iminoglutarate-bound complex of glutamate dehydrogenase from Corynebacterium glutamicum · PMID 28486765 · 10 records
• Crystal structure of the bifunctional N-acetylglucosamine 1-phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamily · PMID 10428949 · 17 records
• Crystal structure of the cofactor-independent monooxygenase SnoaB from Streptomyces nogalater: implications for the reaction mechanism · PMID 20052967 · 7 records
• Crystal structure of the deglycating enzyme fructosamine oxidase (amadoriase II) · PMID 18667417 · 20 records
• Crystal Structure of the Ergothioneine Sulfoxide Synthase from Candidatus Chloracidobacterium thermophilum and Structure-Guided Engineering To Modulate Its Substrate Selectivity · PMID 32257583 · 16 records
• Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity · PMID 19143568 · 8 records
• Crystal Structure of the LysY·LysW Complex from Thermus thermophilus · PMID 26966182 · 10 records
• Crystal structure of the multicopper oxidase from the pathogenic bacterium Campylobacter jejuni CGUG11284: characterization of a metallo-oxidase · PMID 22127520 · 6 records
• Crystal structure of the novel amino-acid racemase isoleucine 2-epimerase from Lactobacillus buchneri · PMID 28471367 · 8 records
• Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases · PMID 19477418 · 13 records
• Crystal structure of Thermus thermophilus tRNA m1A58 methyltransferase and biophysical characterization of its interaction with tRNA · PMID 18262540 · 8 records
• Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination · PMID 16554305 · 24 records
• Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding · PMID 27292129 · 10 records
• Crystal structure of urea carboxylase provides insights into the carboxyltransfer reaction · PMID 22277658 · 7 records
• Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands · PMID 15122882 · 5 records
• Crystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskia · PMID 25670483 · 16 records
• Crystal structure of β-glucosidase 1A from Thermotoga neapolitana and comparison of active site mutants for hydrolysis of flavonoid glucosides · PMID 28142197 · 14 records
• Crystal Structure, Steady-State, and Pre-Steady-State Kinetics of Acinetobacter baumannii ATP Phosphoribosyltransferase · PMID 38150593 · 19 records
• Crystal structures and biochemical analyses of intermediate cleavage peptidase: role of dynamics in enzymatic function · PMID 30582634 · 3 records
• Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus · PMID 21458463 · 4 records
• Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism · PMID 21728995 · 29 records
• Crystal structures and mutagenesis of sucrose hydrolase from Xanthomonas axonopodis pv. glycines: insight into the exclusively hydrolytic amylosucrase fold · PMID 18565544 · 7 records
• Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor · PMID 20690600 · 16 records
• Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases · PMID 26154028 · 8 records
• Crystal structures of ADP and AMPPNP-bound propionate kinase (TdcD) from Salmonella typhimurium: comparison with members of acetate and sugar kinase/heat shock cognate 70/actin superfamily · PMID 16139298 · 3 records
• Crystal Structures of Apo and Liganded 4-Oxalocrotonate Decarboxylase Uncover a Structural Basis for the Metal-Assisted Decarboxylation of a Vinylogous β-Keto Acid · PMID 27082660 · 5 records
• Crystal structures of archaeal 2-oxoacid:ferredoxin oxidoreductases from Sulfolobus tokodaii · PMID 27619895 · 9 records
• Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate… · PMID 18434308 · 1 record
• Crystal structures of glycoside hydrolase family 136 lacto-N-biosidases from monkey gut- and human adult gut bacteria · PMID 35092420 · 8 records
• Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity · PMID 20299452 · 14 records
• Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition · PMID 19075558 · 3 records
• Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation · PMID 16135565 · 14 records
• Crystal structures of intermediates in the nitroalkane oxidase reaction · PMID 19265437 · 5 records
• Crystal structures of lysine-preferred racemases, the non-antibiotic selectable markers for transgenic plants · PMID 23118975 · 9 records
• Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates · PMID 16870616 · 9 records
• Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities · PMID 26738801 · 6 records
• Crystal structures of Pseudomonas aeruginosa guanidinobutyrase and guanidinopropionase, members of the ureohydrolase superfamily · PMID 21600989 · 7 records
• Crystal structures of rice (Oryza sativa) glyceraldehyde-3-phosphate dehydrogenase complexes with NAD and sulfate suggest involvement of Phe37 in NAD binding for catalysis · PMID 22903596 · 16 records
• Crystal Structures of the C-Glycosyltransferase UGT708C1 from Buckwheat Provide Insights into the Mechanism of C-Glycosylation · PMID 32699169 · 22 records
• Crystal structures of the Helicobacter pylori MTAN enzyme reveal specific interactions between S-adenosylhomocysteine and the 5'-alkylthio binding subsite · PMID 23148563 · 6 records
• Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in… · PMID 15788389 · 14 records
• Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. alcohol dehydrogenase toward NADH cosubstrate specificity · PMID 23686719 · 12 records
• Crystallographic analysis of the reaction cycle of 2',3'-cyclic nucleotide 3'-phosphodiesterase, a unique member of the 2H phosphoesterase family · PMID 23831225 · 5 records
• Crystallographic and activity-based evidence for thumb flexibility and its relevance in glycoside hydrolase family 11 xylanases · PMID 19422059 · 22 records
• Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function · PMID 17371050 · 7 records
• Crystallographic and mutational analyses of cystathionine β-synthase in the H₂ S-synthetic gene cluster in Lactobacillus plantarum · PMID 28127810 · 22 records
• Crystallographic evidence for a domain motion in rat nucleoside triphosphate diphosphohydrolase (NTPDase) 1 · PMID 22100451 · 26 records
• Crystallographic snapshots of oxalyl-CoA decarboxylase give insights into catalysis by nonoxidative ThDP-dependent decarboxylases · PMID 17637344 · 9 records
• Crystallographic study to determine the substrate specificity of an L-serine-acetylating enzyme found in the D-cycloserine biosynthetic pathway · PMID 23396912 · 8 records
• Crystallographic, kinetic, and calorimetric investigation of PKA interactions with L-type calcium channels and Rad GTPase · PMID 39615689 · 12 records
• CugP is a novel ubiquitous non-GalU-type bacterial UDP-glucose pyrophosphorylase found in cyanobacteria · PMID 24727225 · 4 records
• Cumulative effect of amino acid replacements results in enhanced thermostability of potato type L alpha-glucan phosphorylase · PMID 16151135 · 16 records
• Cumulative stabilizing effects of glycine to alanine substitutions in Bacillus subtilis neutral protease · PMID 1438165 · 16 records
• Cuprous oxidase activity of yeast Fet3p and human ceruloplasmin: implication for function · PMID 14623105 · 4 records
• Customization of Ethylene Glycol (EG)-Induced BmoR-Based Biosensor for the Directed Evolution of PET Degrading Enzymes · PMID 39927766 · 2 records
• Cyanophage MazG is a pyrophosphohydrolase but unable to hydrolyse magic spot nucleotides · PMID 30809954 · 18 records
• CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis · PMID 12970475 · 4 records
• CYP90A1/CPD, a brassinosteroid biosynthetic cytochrome P450 of Arabidopsis, catalyzes C-3 oxidation · PMID 22822057 · 6 records
• CYP96T1 of Narcissus sp. aff. pseudonarcissus Catalyzes Formation of the Para-Para' C-C Phenol Couple in the Amaryllidaceae Alkaloids · PMID 26941773 · 4 records
• CysK2 from Mycobacterium tuberculosis is an O-phospho-L-serine-dependent S-sulfocysteine synthase · PMID 25022854 · 8 records
• Cysteine 10 is critical for the activity of Ochrobactrum anthropi glutathione transferase and its mutation to alanine causes the preferential binding of glutathione to the H-site · PMID 18076047 · 6 records
• Cysteine activation is an inherent in vitro property of prolyl-tRNA synthetases · PMID 12130657 · 26 records
• Cysteine and keto acids modulate mosquito kynurenine aminotransferase catalyzed kynurenic acid production · PMID 15556614 · 13 records
• Cysteine Disulfide Traps Reveal Distinct Conformational Ensembles in Dengue Virus NS2B-NS3 Protease · PMID 30472839 · 13 records
• Cysteine sulfinate desulfinase, a NIFS-like protein of Escherichia coli with selenocysteine lyase and cysteine desulfurase activities. Gene cloning, purification, and characterization of a novel… · PMID 9278392 · 4 records
• Cysteine synthase (O-acetylserine (thiol) lyase) substrate specificities classify the mitochondrial isoform as a cyanoalanine synthase · PMID 10948226 · 15 records
• Cytidine Diphosphoramidate Kinase: An Enzyme Required for the Biosynthesis of the O-Methyl Phosphoramidate Modification in the Capsular Polysaccharides of Campylobacter jejuni · PMID 29578334 · 10 records
• Cytochrome b5 reductase: role of the si-face residues, proline 92 and tyrosine 93, in structure and catalysis · PMID 15709757 · 30 records
• Cytochrome cd1, reductive activation and kinetic analysis of a multifunctional respiratory enzyme · PMID 11709555 · 31 records
• Cytochrome P450 2E polymorphism in feline liver · PMID 16168565 · 5 records
• Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps · PMID 15772082 · 21 records
• Cytochromes P-450 from cassava (Manihot esculenta Crantz) catalyzing the first steps in the biosynthesis of the cyanogenic glucosides linamarin and lotaustralin. Cloning, functional expression in… · PMID 10636899 · 2 records
• Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy · PMID 12907246 · 19 records
• Cytosolic mercaptopyruvate sulfurtransferase is evolutionarily related to mitochondrial rhodanese. Striking similarity in active site amino acid sequence and the increase in the mercaptopyruvate… · PMID 7608189 · 10 records
• Cytosolic pyruvate kinase: subunit composition, activity, and amount in developing castor and soybean seeds, and biochemical characterization of the purified castor seed enzyme · PMID 16049677 · 8 records
• Cytosolic Triosephosphate Isomerase from Arabidopsis thaliana Is Reversibly Modified by Glutathione on Cysteines 127 and 218 · PMID 28066493 · 6 records
• Cytotoxic, Anti-Proliferative and Apoptosis Activity of l-Amino Acid Oxidase from Malaysian Cryptelytrops purpureomaculatus (CP-LAAO) Venom on Human Colon Cancer Cells · PMID 29890640 · 1 record
• D-2-hydroxy-4-methylvalerate dehydrogenase from Lactobacillus delbrueckii subsp. bulgaricus. II. Mutagenic analysis of catalytically important residues · PMID 9063466 · 30 records
• D-arabinose dehydrogenase and biosynthesis of erythroascorbic acid in Candida albicans · PMID 8841374 · 5 records
• D-erythrulose reductase can also reduce diacetyl: further purification and characterization of D-erythrulose reductase from chicken liver · PMID 9538249 · 12 records
• D-Galactose dehydrogenase from Pseudomonas fluorescens. Purification, properties and structure · PMID 4153311 · 4 records
• D-ribose-5-phosphate isomerase B from Escherichia coli is also a functional D-allose-6-phosphate isomerase, while the Mycobacterium tuberculosis enzyme is not · PMID 18640127 · 5 records
• D-ribose-5-phosphate isomerase from spinach: heterologous overexpression, purification, characterization, and site-directed mutagenesis of the recombinant enzyme · PMID 10620366 · 7 records
• D-Xylose (D-glucose) isomerase from Arthrobacter strain N.R.R.L. B3728. Purification and properties · PMID 1854338 · 8 records
• D-xylose degradation pathway in the halophilic archaeon Haloferax volcanii · PMID 19584053 · 12 records
• D-Xylose metabolism by Candida intermedia: isolation and characterisation of two forms of aldose reductase with different coenzyme specificities · PMID 10681056 · 6 records
• DapE can function as an aspartyl peptidase in the presence of Mn2+ · PMID 12896993 · 3 records
• Data sets on the interaction of FKBP35 from Plasmodium knowlesi and Hsp90 C-terminal pentapeptide · PMID 42376286 · 3 records
• Dcs2, a novel stress-induced modulator of m7GpppX pyrophosphatase activity that locates to P bodies · PMID 16963086 · 4 records
• De novo biosynthesis of 4,6-dihydroxycoumarin in Escherichia coli · PMID 40013057 · 8 records
• De novo cysteine biosynthesis in Pseudomonas aeruginosa: Characterization of the two main cysteine synthase isoforms · PMID 41541697 · 18 records
• Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes · PMID 23972005 · 41 records
• Debottlenecking 4-hydroxybenzoate hydroxylation in Pseudomonas putida KT2440 improves muconate productivity from p-coumarate · PMID 34982998 · 15 records
• Decaprenyl diphosphate synthesis in Mycobacterium tuberculosis · PMID 15516568 · 6 records
• Deciphering the kinetic mechanisms controlling selected plant ADP-glucose pyrophosphorylases · PMID 23603314 · 18 records
• Deciphering the molecular basis for nucleotide selection by the West Nile virus RNA helicase · PMID 20421212 · 22 records
• Deciphering the role of recurrent FAD-dependent enzymes in bacterial phosphonate catabolism · PMID 37876809 · 7 records
• Decoding in-cell respiratory enzyme dynamics by label-free in situ electrochemistry · PMID 40117313 · 8 records
• Decoding isozyme-specific substrate recognition in protein arginine deiminases by in vitro lysate-based citrullination mapping · PMID 42754570 · 13 records
• Decoding the substrate specificity landscape of a promiscuous enzyme through multi-substrate mutational scanning · PMID 41748636 · 223 records
• Deepening TOL and TOU catabolic pathways of Pseudomonas sp. OX1: cloning, sequencing and characterization of the lower pathways · PMID 23009925 · 7 records
• Defining sequence space and reaction products within the cyanuric acid hydrolase (AtzD)/barbiturase protein family · PMID 22730121 · 6 records
• Defining substrate specificities of human RNA capping methyltransferases through quantitative assessment of independent yet cooperative activities · PMID 41432309 · 10 records
• Defining the cytosolic pathway of glutathione degradation in Arabidopsis thaliana: role of the ChaC/GCG family of γ-glutamyl cyclotransferases as glutathione-degrading enzymes and AtLAP1 as the… · PMID 25716890 · 5 records
• Defining the role of phosphomethylethanolamine N-methyltransferase from Caenorhabditis elegans in phosphocholine biosynthesis by biochemical and kinetic analysis · PMID 16681378 · 3 records
• Definition of the extended substrate specificity determinants for beta-tryptases I and II · PMID 11438529 · 8 records
• Defluorination Capability of l-2-Haloacid Dehalogenases in the HAD-Like Hydrolase Superfamily Correlates with Active Site Compactness · PMID 34643018 · 10 records
• Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme · PMID 12542396 · 9 records
• Dehydration is catalyzed by glutamate-136 and aspartic acid-135 active site residues in Escherichia coli dTDP-glucose 4,6-dehydratase · PMID 11601973 · 10 records
• Dehydrogenase versus oxidase function: the interplay between substrate binding and flavin microenvironment · PMID 39781101 · 25 records
• Dehydroquinate dehydratase/shikimate dehydrogenases involved in gallate biosynthesis of the aluminum-tolerant tree species Eucalyptus camaldulensis · PMID 33346890 · 21 records
• Deletion variants of L-hydroxyisocaproate dehydrogenase. Probing substrate specificity · PMID 8055963 · 41 records
• Delineation of the roles of amino acids involved in the catalytic functions of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase · PMID 11106479 · 66 records
• Delta 5-3beta-hydroxysteroid dehydrogenase (3 beta HSD) from Digitalis lanata. Heterologous expression and characterisation of the recombinant enzyme · PMID 17564944 · 8 records
• Demonstration of 3 alpha(17 beta)-hydroxysteroid dehydrogenase distinct from 3 alpha-hydroxysteroid dehydrogenase in hamster liver · PMID 2317205 · 32 records
• Demonstration of glyoxalase II in rat liver mitochondria. Partial purification and occurrence in multiple forms · PMID 3382669 · 21 records
• Denuded peptidoglycan oligosaccharides enable the biochemical investigation of bacterial cell wall recognition, modification, and degradation · PMID 42607889 · 4 records
• Deoxynucleoside kinases encoded by the yaaG and yaaF genes of Bacillus subtilis. Substrate specificity and kinetic analysis of deoxyguanosine kinase with UTP as the preferred phosphate donor · PMID 11078735 · 9 records
• Deoxyribonucleoside kinases activate nucleoside antibiotics in severely pathogenic bacteria · PMID 17526755 · 6 records
• Deoxyribosyl transfer catalysis with trans-N-deoxyribosylase. Kinetic study of purine(pyrimidine) to pyrimidine(purine) trans-N-deoxyribosylase · PMID 1082813 · 8 records
• Description of a versatile peroxidase involved in the natural degradation of lignin that has both manganese peroxidase and lignin peroxidase substrate interaction sites · PMID 10187820 · 16 records
• Description of the rate-limiting hydrogen tunneling mechanism for plant 9- and 13-lipoxygenases · PMID 42227275 · 10 records
• Design and directed evolution of a dideoxy purine nucleoside phosphorylase · PMID 20525731 · 38 records
• Design and Engineering of an Artificial Bifunctional N-Deacetylase/N-Sulfotransferase for the Biosynthesis of N-Sulfated Heparosan · PMID 42429608 · 10 records
• Design and synthesis of new substrates of HtrA2 protease · PMID 25640585 · 6 records
• Design of an active fragment of a class II aminoacyl-tRNA synthetase and its significance for synthetase evolution · PMID 9131996 · 16 records
• Design of an adenosine phosphorylase by active-site modification of murine purine nucleoside phosphorylase. Enzyme kinetics and molecular dynamics simulation of Asn-243 and Lys-244 substitutions of… · PMID 10567244 · 12 records
• Design of an ectoine-responsive AraC mutant and its application in metabolic engineering of ectoine biosynthesis · PMID 26051748 · 6 records
• Design of Functionalized Silica Immobilization of PETase from Kibdelosporangium aridum: Comparison of Glyoxyl and Glutaraldehyde Strategies for PET Depolymerization · PMID 42146182 · 4 records
• Design of reverse transcriptase-specific nucleosides to visualize early steps of HIV-1 replication by click labeling · PMID 31201270 · 9 records
• Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine · PMID 20971807 · 6 records
• Design, synthesis, and biological evaluation of novel human 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP) substrates · PMID 15911263 · 34 records
• Designed Water Capture in Terpene Synthase Catalysis · PMID 41816904 · 4 records
• Designing an ecofriendly catalyst for a sustainable use of water resources · PMID 41623564 · 11 records
• Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity · PMID 24239948 · 4 records
• Desulfovibrio DA2_CueO is a novel multicopper oxidase with cuprous, ferrous and phenol oxidase activity · PMID 28749328 · 4 records
• Detailed dissection of a new mechanism for glycoside cleavage: alpha-1,4-glucan lyase · PMID 14596624 · 15 records
• Detailed kinetic analysis and identification of the nucleophile in alpha-L-arabinofuranosidase from Geobacillus stearothermophilus T-6, a family 51 glycoside hydrolase · PMID 12221104 · 17 records
• Detection and function of the intramolecular disulfide bond in arginine racemase: an enzyme with broad substrate specificity · PMID 20564572 · 16 records
• Detection of kinetically abnormal argininosuccinate synthase in neonatal citrullinemia by conversion of citrulline to arginine in intact fibroblasts · PMID 2791302 · 20 records
• Determinants for tRNA-dependent pretransfer editing in the synthetic site of isoleucyl-tRNA synthetase · PMID 25207837 · 13 records
• Determinants of chymotrypsin C cleavage specificity in the calcium-binding loop of human cationic trypsinogen · PMID 23035638 · 33 records
• Determinants of L-aspartate and IMP recognition in Escherichia coli adenylosuccinate synthetase · PMID 11781326 · 36 records
• Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase · PMID 26563764 · 12 records
• Determinants of nucleotide-binding selectivity of malic enzyme · PMID 21980421 · 70 records
• Determinants of ribose specificity in RNA polymerization: effects of Mn2+ and deoxynucleoside monophosphate incorporation into transcripts · PMID 9354643 · 16 records
• Determinants of substrate specificity in D-3-phosphoglycerate dehydrogenase. Conversion of the M. tuberculosis enzyme from one that does not use α-ketoglutarate as a substrate to one that does · PMID 31344342 · 9 records
• Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362 · PMID 16757477 · 16 records
• Determination of Alkyl-Donor Promiscuity of Tyrosine-O-Prenyltransferase SirD from Leptosphaeria maculans · PMID 28960770 · 11 records
• Determination of branched-chain L-amino-acid aminotransferase activity · PMID 10989414 · 16 records
• Determination of key residues for catalysis and RNA cleavage specificity: one mutation turns RNase II into a "SUPER-ENZYME" · PMID 19458082 · 2 records
• Determination of specific activities and kinetic constants of biotinidase and lipoamidase in LEW rat and Lactobacillus casei (Shirota) · PMID 16876490 · 114 records
• Determination of the crystal structure and substrate specificity of ananain · PMID 31306685 · 11 records
• Determination of the metal ion dependence and substrate specificity of a hydratase involved in the degradation pathway of biphenyl/chlorobiphenyl · PMID 15691330 · 4 records
• Determination of the roles of Glu-461 in beta-galactosidase (Escherichia coli) using site-specific mutagenesis · PMID 1969405 · 42 records
• Detoxification function of the Arabidopsis sulphotransferase AtSOT12 by sulphonation of xenobiotics · PMID 25736839 · 20 records
• Developing an E. coli heterologous expression system for characterizing a marine debrominase from Roseobacter sp · PMID 41930973 · 2 records
• Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide · PMID 19663506 · 7 records
• Developing promiscuous glycosidases for glycoside synthesis: residues W433 and E432 in Sulfolobus solfataricus beta-glycosidase are important glucoside- and galactoside-specificity determinants · PMID 15846595 · 51 records
• Development of a covalent inhibitor of gut bacterial bile salt hydrolases · PMID 32042200 · 7 records
• Development of a mutagenesis, expression and purification system for yeast phosphoglycerate mutase. Investigation of the role of active-site His181 · PMID 1386023 · 8 records
• Development of a protease-resistant ADAMTS13 to improve stability against proteolytic degradation · PMID 40127394 · 5 records
• Development of a Spectrophotometric Assay for the Cysteine Desulfurase from Staphylococcus aureus · PMID 40001373 · 6 records
• Development of Cathepsin B‑Activatable Cell-Penetrating Peptides for Tumor Targeting · PMID 41988367 · 180 records
• Development of the first internally-quenched fluorescent substrates of human cathepsin C: The application in the enzyme detection in biological samples · PMID 27746119 · 12 records
• Development, validation and application of a 96-well enzymatic assay based on LC-ESI-MS/MS quantification for the screening of selective inhibitors against Mycobacterium tuberculosis purine… · PMID 27769382 · 6 records
• DHS-21, a dicarbonyl/L-xylulose reductase (DCXR) ortholog, regulates longevity and reproduction in Caenorhabditis elegans · PMID 21477590 · 9 records
• Dictyostelium discoideum salvages purine deoxyribonucleosides by highly specific bacterial-like deoxyribonucleoside kinases · PMID 17448496 · 6 records
• Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase · PMID 10692580 · 4 records
• Differences and Compatibility between Human and Porcine Fibrinolytic Components toward Plasmin Generation and Fibrin Degradation · PMID 41567719 · 12 records
• Differences in Binding Affinity Among Cell-cycle CDK and Cyclin Pairs · PMID 39826708 · 20 records
• Differences in substrate and inhibitor sequence specificity of human, mouse and rat tissue kallikreins · PMID 15040788 · 22 records
• Differences in substrate specificity and kinetic properties of the recombinant hexokinases HXK1 and HXK2 from Entamoeba histolytica · PMID 10613700 · 17 records
• Differences in the catalytic mechanisms of mesophilic and thermophilic indole-3-glycerol phosphate synthase enzymes at their adaptive temperatures · PMID 22274606 · 6 records
• Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase · PMID 12416982 · 13 records
• Differences in the P1' substrate specificities of pepsin A and chymosin · PMID 19819898 · 16 records
• Differences in the roles of conserved glutamic acid residues in the active site of human class 3 and class 2 aldehyde dehydrogenases · PMID 10548037 · 6 records
• Differences in transition state stabilization between thermolysin (EC 3.4.24.27) and neprilysin (EC 3.4.24.11) · PMID 9827548 · 6 records
• Different effects of sulfur amino acids on prolidase and prolinase activity in normal and prolidase-deficient human erythrocytes · PMID 16899234 · 30 records
• Different functions between human monomeric carbonyl reductase 3 and carbonyl reductase 1 · PMID 18493841 · 9 records
• Different fungal manganese-oxidizing peroxidases: a comparison between Bjerkandera sp. and Phanerochaete chrysosporium · PMID 10682282 · 19 records
• Different properties of the central and peripheral forms of human tryptophan hydroxylase · PMID 15663479 · 10 records
• Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase · PMID 34256657 · 15 records
• Different ways to transport ammonia in human and Mycobacterium tuberculosis NAD⁺ synthetases · PMID 31911602 · 18 records
• Differential active site loop conformations mediate promiscuous activities in the lactonase SsoPox · PMID 24086491 · 70 records
• Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake · PMID 14557274 · 16 records
• Differential contributions of NADPH-cytochrome P450 oxidoreductase FAD binding site residues to flavin binding and catalysis · PMID 11022049 · 18 records
• Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain · PMID 16581093 · 22 records
• Differential recognition of Old World and New World arenavirus envelope glycoproteins by subtilisin kexin isozyme 1 (SKI-1)/site 1 protease (S1P) · PMID 23536681 · 26 records
• Differential recognition of the type I and II H antigen acceptors by the human ABO(H) blood group A and B glycosyltransferases · PMID 16326711 · 6 records
• Differential redox and electron-transfer properties of purified yeast, plant and human NADPH-cytochrome P-450 reductases highly modulate cytochrome P-450 activities · PMID 9990323 · 20 records
• Differential regulation of opposing RelMtb activities by the aminoacylation state of a tRNA.ribosome.mRNA.RelMtb complex · PMID 10995231 · 22 records
• Differential regulation of SIRT5 activity by reduced nicotinic acid riboside (NARH) · PMID 41409579 · 8 records
• Differential RNA-dependent ATPase activities of four rRNA processing yeast DEAD-box proteins · PMID 18975973 · 8 records
• Differential substrate behaviour of phenol and aniline derivatives during oxidation by horseradish peroxidase: kinetic evidence for a two-step mechanism · PMID 15158733 · 28 records
• Differentiating the Substrate Profiles of Inflammatory Caspases Using Extended Förster Resonance Energy Transfer-Based Peptide Substrates · PMID 41321079 · 5 records
• Dihydrodiol dehydrogenase activities of rabbit liver are associated with hydroxysteroid dehydrogenases and aldo-keto reductases · PMID 1576998 · 21 records
• Dihydrodiol dehydrogenases in guinea pig liver · PMID 3535806 · 34 records
• Dimeric 3-phosphoglycerate kinases from hyperthermophilic Archaea. Cloning, sequencing and expression of the 3-phosphoglycerate kinase gene of Pyrococcus woesei in Escherichia coli and… · PMID 7588750 · 18 records
• Dimeric crystal structure of rabbit L-gulonate 3-dehydrogenase/lambda-crystallin: insights into the catalytic mechanism · PMID 20620150 · 10 records
• Dimeric dihydrodiol dehydrogenase in monkey kidney. Substrate specificity, stereospecificity of hydrogen transfer, and distribution · PMID 2697716 · 10 records
• Dimerization and enzymatic activity of fungal 17beta-hydroxysteroid dehydrogenase from the short-chain dehydrogenase/reductase superfamily · PMID 16359545 · 4 records
• Dimerization interface of 3-hydroxyacyl-CoA dehydrogenase tunes the formation of its catalytic intermediate · PMID 24763278 · 4 records
• Dimerization mediates thermo-adaptation, substrate affinity and transglycosylation in a highly thermostable maltogenic amylase of Geobacillus thermoleovorans · PMID 24069213 · 25 records
• Dimerization-Dependent Trans-Domain Coupling Enables Intermediate Transfer in Fungal Haloacid Dehalogenase-Like Terpene Cyclases · PMID 42139319 · 14 records
• Dimethylarginine:pyruvate aminotransferase in rats. Purification, properties, and identity with alanine:glyoxylate aminotransferase 2 · PMID 2123486 · 12 records
• Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses · PMID 12651859 · 36 records
• Dioxygenases without requirement for cofactors: identification of amino acid residues involved in substrate binding and catalysis, and testing for rate-limiting steps in the reaction of… · PMID 16187153 · 30 records
• Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli) · PMID 19472413 · 10 records
• Direct comparison of gluco-oligosaccharide oxidase variants and glucose oxidase: substrate range and H₂O₂ stability · PMID 27869125 · 10 records
• Direct Comparison of the Enzymatic Characteristics and Superoxide Production of the Four Aldehyde Oxidase Enzymes Present in Mouse · PMID 28526768 · 18 records
• Direct comparison of the four aldehyde oxidase enzymes present in mouse gives insight into their substrate specificities · PMID 29370288 · 110 records
• Direct kinetic evidence that lysine 215 is involved in the phospho-transfer step of human 3-phosphoglycerate kinase · PMID 19530648 · 4 records
• Direct over-expression, characterization and H2O2 stability study of active Pleurotus eryngii versatile peroxidase in Escherichia coli · PMID 22566208 · 8 records
• Direct Participation of a Peripheral Side Chain of a Corrin Ring in Coenzyme B₁₂ Catalysis · PMID 29797764 · 6 records
• Directed evolution and site-specific mutagenesis of L-isoleucine dioxygenase derived from Bacillus weihenstephanensis · PMID 29869760 · 8 records
• Directed evolution and structural analysis of NADPH-dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics · PMID 23913421 · 6 records
• Directed Evolution Improves the Enzymatic Synthesis of L-5-Hydroxytryptophan by an Engineered Tryptophan Synthase · PMID 34097254 · 9 records
• Directed Evolution of a Fluorinase for Improved Fluorination Efficiency with a Non-native Substrate · PMID 27739177 · 6 records
• Directed evolution of a histone acetyltransferase--enhancing thermostability, whilst maintaining catalytic activity and substrate specificity · PMID 18959749 · 29 records
• Directed evolution of a temperature-, peroxide- and alkaline pH-tolerant versatile peroxidase · PMID 21980920 · 17 records
• Directed evolution of a thermostable phosphite dehydrogenase for NAD(P)H regeneration · PMID 16204481 · 37 records
• Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily · PMID 20980257 · 32 records
• Directed evolution of an endoinulinase from Talaromyces purpureogenus toward efficient production of inulooligosaccharides · PMID 29388362 · 4 records
• Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars · PMID 11094340 · 16 records
• Directed evolution of D-sialic acid aldolase to L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolase · PMID 15967977 · 23 records
• Directed evolution of mandelate racemase by a novel high-throughput screening method · PMID 27557723 · 16 records
• Directed evolution of rubisco in Escherichia coli reveals a specificity-determining hydrogen bond in the form II enzyme · PMID 18004873 · 15 records
• Directed evolution of Streptomyces clavuligerus deacetoxycephalosporin C synthase for enhancement of penicillin G expansion · PMID 16332884 · 22 records
• Directed evolution of the alpha-L-fucosidase from Thermotoga maritima into an alpha-L-transfucosidase · PMID 17240986 · 25 records
• Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation · PMID 26553994 · 10 records
• Directed evolution of thermotolerant malic enzyme for improved malate production · PMID 23932397 · 12 records
• Directed evolution of unspecific peroxygenase from Agrocybe aegerita · PMID 24682297 · 15 records
• Directed evolution on the cold adapted properties of TAB5 alkaline phosphatase · PMID 18411226 · 11 records
• Directed modification of l-LcLDH1, an l-lactate dehydrogenase from Lactobacillus casei, to improve its specific activity and catalytic efficiency towards phenylpyruvic acid · PMID 29800600 · 6 records
• Directed mutations in the poorly defined region of porcine liver fructose-1,6-bisphosphatase significantly affect catalysis and the mechanism of AMP inhibition · PMID 9651342 · 10 records
• Directing sequence-specific proteolysis to new targets. The influence of loop size and target sequence on selective proteolysis by tissue-type plasminogen activator and urokinase-type plasminogen… · PMID 9468480 · 20 records
• Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii. Implications for this disulfide metabolism of anaerobic hyperthermophiles · PMID 15720393 · 6 records
• Discovery and characterization of a marine bacterial SAM-dependent chlorinase · PMID 18059261 · 7 records
• Discovery and characterization of a novel chromosomally encoded aminoglycoside O-nucleotidyltransferase gene, designated ant(9)-Ie, in a strain of… · PMID 42312034 · 1 record
• Discovery and characterization of a putrescine oxidase from Rhodococcus erythropolis NCIMB 11540 · PMID 18183391 · 12 records
• Discovery and characterization of an FAD-dependent glucose 6-dehydrogenase · PMID 39814229 · 15 records
• Discovery and Characterization of Mannan-Specialized GH5 Endo-1,4-β-mannanases: a Strategy for Açaí (Euterpe oleracea Mart.) Seeds Upgrading · PMID 39680639 · 3 records
• Discovery and design of novel glucoamylases suitable for raw starch hydrolysis at moderate temperatures via an integrated bioinformatics-assisted strategy · PMID 41530843 · 4 records
• Discovery and Functional Characterization of SnFDHal, an Efficient Tryptophan 5-Halogenase from Streptomyces noursei · PMID 41205041 · 3 records
• Discovery and molecular and biocatalytic properties of hydroxynitrile lyase from an invasive millipede, Chamberlinius hualienensis · PMID 26261304 · 9 records
• Discovery and structural analysis of a phloretin hydrolase from the opportunistic human pathogen Mycobacterium abscessus · PMID 30784195 · 6 records
• Discovery and structure determination of the orphan enzyme isoxanthopterin deaminase · PMID 20415463 · 4 records
• Discovery and Synthetic Applications of a NAD(P)H-Dependent Reductive Aminase from Rhodococcus erythropolis · PMID 39781332 · 2 records
• Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening · PMID 19000819 · 16 records
• Discovery of a eugenol oxidase from Rhodococcus sp. strain RHA1 · PMID 17419730 · 6 records
• Discovery of a Kojibiose Phosphorylase in Escherichia coli K-12 · PMID 29684280 · 19 records
• Discovery of a novel L-lyxonate degradation pathway in Pseudomonas aeruginosa PAO1 · PMID 24831290 · 13 records
• Discovery of a Previously Unrecognized Ribonuclease from Escherichia coli That Hydrolyzes 5'-Phosphorylated Fragments of RNA · PMID 25871919 · 21 records
• Discovery of a substrate selectivity switch in tyrosine ammonia-lyase, a member of the aromatic amino acid lyase family · PMID 17185227 · 14 records
• Discovery of additional members of the tyrosine aminomutase enzyme family and the mutational analysis of CmdF · PMID 19222035 · 3 records
• Discovery of an L-fucono-1,5-lactonase from cog3618 of the amidohydrolase superfamily · PMID 23214453 · 33 records
• Discovery of ancestral L-ornithine and L-lysine decarboxylases reveals parallel, pseudoconvergent evolution of polyamine biosynthesis · PMID 34560100 · 22 records
• Discovery of cellobionic acid phosphorylase in cellulolytic bacteria and fungi · PMID 24055472 · 8 records
• Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the D-mannonate dehydratase subgroup · PMID 24697546 · 34 records
• Discovery of Lacto-N-Biosidases and a Novel N-Acetyllactosaminidase Activity in the CAZy Family GH20: Functional Diversity and Structural Insights · PMID 39239753 · 14 records
• Discovery of nigerose phosphorylase from Clostridium phytofermentans · PMID 21808968 · 7 records
• Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation · PMID 21983602 · 8 records
• Discovery of solabiose phosphorylase and its application for enzymatic synthesis of solabiose from sucrose and lactose · PMID 34997180 · 4 records
• Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization · PMID 17240984 · 5 records
• Discovery of Two Novel Oxidases Using a High-Throughput Activity Screen · PMID 34709726 · 22 records
• Discovery of two β-1,2-mannoside phosphorylases showing different chain-length specificities from Thermoanaerobacter sp. X-514 · PMID 25500577 · 19 records
• Discovery of β-1,4-D-mannosyl-N-acetyl-D-glucosamine phosphorylase involved in the metabolism of N-glycans · PMID 23943617 · 8 records
• Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates · PMID 21599834 · 26 records
• Discrimination of aliphatic substrates by a single amino acid substitution in Bacillus badius and Bacillus sphaericus phenylalanine dehydrogenases · PMID 19270409 · 17 records
• Discrimination of esterase and peptidase activities of acylaminoacyl peptidase from hyperthermophilic Aeropyrum pernix K1 by a single mutation · PMID 16670095 · 14 records
• Disease associated missense substitutions disrupt structural stability and catalytic function of 4-hydroxyphenylpyruvate dioxygenase · PMID 42140431 · 7 records
• Disease variants of human Δ¹-pyrroline-5-carboxylate reductase 2 (PYCR2) · PMID 33771508 · 18 records
• Disease variants of the human mitochondrial DNA helicase encoded by C10orf2 differentially alter protein stability, nucleotide hydrolysis, and helicase activity · PMID 20659899 · 22 records
• Disordered N-termini enhance the thermostability of SGNH-hydrolase family polyesterases · PMID 41427655 · 8 records
• Disruption of key NADH-binding pocket residues of the Mycobacterium tuberculosis InhA affects DD-CoA binding ability · PMID 28680153 · 10 records
• Dissecting a charged network at the active site of orotidine-5'-phosphate decarboxylase · PMID 11278904 · 3 records
• Dissecting a two-domain alginate lyase of family PL6 reveals a mechanistic basis for substrate specificity and enzyme activity · PMID 41638429 · 4 records
• Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT(4') · PMID 21040710 · 18 records
• Dissecting the essential role of N-glycosylation in catalytic performance of xanthan lyase · PMID 38647758 · 4 records
• Dissecting the functional roles of the conserved NXXE and HXE motifs of the ADP-dependent glucokinase from Thermococcus litoralis · PMID 26428088 · 10 records
• Dissecting the metabolic roles of pteridine reductase 1 in Trypanosoma brucei and Leishmania major · PMID 21239486 · 9 records
• Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase · PMID 10653632 · 26 records
• Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket · PMID 8349597 · 48 records
• Distal heme pocket residues of B-type dye-decolorizing peroxidase: arginine but not aspartate is essential for peroxidase activity · PMID 22308037 · 5 records
• Distal substrate interactions enhance plasmepsin activity · PMID 15574427 · 14 records
• Distinct biochemical properties of human serine hydroxymethyltransferase compared with the Plasmodium enzyme: implications for selective inhibition · PMID 24698160 · 6 records
• Distinct classes of glyoxalase I: metal specificity of the Yersinia pestis, Pseudomonas aeruginosa and Neisseria meningitidis enzymes · PMID 15270717 · 6 records
• Distinct conformation-mediated functions of an active site loop in the catalytic reactions of NAD-dependent D-lactate dehydrogenase and formate dehydrogenase · PMID 15734738 · 14 records
• Distinct contributions of O-acetylserine sulfhydrylases to cysteine biosynthesis in Pseudomonas aeruginosa · PMID 41676964 · 14 records
• Distinct Enzyme-Substrate Interactions Revealed by Two Dimensional Kinetic Comparison between Dehaloperoxidase-Hemoglobin and Horseradish Peroxidase · PMID 26375307 · 16 records
• Distinct enzymic functional groups are required for the phosphomonoesterase and phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase/phosphatase · PMID 16675457 · 30 records
• Distinct Mechanisms of Acetic Acid Inhibition in Thermophilic GH10 and GH11 Xylanases · PMID 42014366 · 6 records
• Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase eta · PMID 16116089 · 31 records
• Distinct photorespiratory reactions are preferentially catalyzed by glutamate:glyoxylate and serine:glyoxylate aminotransferases in rice · PMID 25528301 · 12 records
• Distinct properties of the five UDP-D-glucose/UDP-D-galactose 4-epimerase isoforms of Arabidopsis thaliana · PMID 16644739 · 19 records
• Distinct substrate specificities and unusual substrate flexibilities of two hydroxycinnamoyltransferases, rosmarinic acid synthase and hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl-transferase… · PMID 21318289 · 58 records
• Distinction between Cytosol and Chloroplast Fructose-Bisphosphate Aldolases from Pea, Wheat, and Corn Leaves · PMID 16664617 · 16 records
• Distinctive features of the two classes of eukaryotic peptide deformylases · PMID 11733990 · 30 records
• Distribution and biochemical properties of an M1-family aminopeptidase in Plasmodium falciparum indicate a role in vacuolar hemoglobin catabolism · PMID 21659511 · 12 records
• Distribution and evolution of the serine/aspartate racemase family in invertebrates. II. Frequent and widespread parallel evolution of aspartate racemase · PMID 35997160 · 16 records
• Distribution and evolution of the serine/aspartate racemase family in plants · PMID 31622858 · 26 records
• Divergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB) · PMID 20050615 · 10 records
• Divergence of catalytic mechanism within a glycosidase family provides insight into evolution of carbohydrate metabolism by human gut flora · PMID 18848471 · 12 records
• Divergence of function in the hot dog fold enzyme superfamily: the bacterial thioesterase YciA · PMID 18247525 · 42 records
• Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates · PMID 33139728 · 40 records
• Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases · PMID 16770009 · 30 records
• Divergent evolution of function in the ROK sugar kinase superfamily: role of enzyme loops in substrate specificity · PMID 17979299 · 35 records
• Divergent evolution of ligand binding in the o-succinylbenzoate synthase family · PMID 24060347 · 25 records
• Divergent roles in Arabidopsis thaliana development and defense of two homologous genes, aberrant growth and death2 and AGD2-LIKE DEFENSE RESPONSE PROTEIN1, encoding novel aminotransferases · PMID 14729919 · 15 records
• Diverse allosteric and catalytic functions of tetrameric d-lactate dehydrogenases from three Gram-negative bacteria · PMID 25401076 · 48 records
• Diverse evolutionary trajectories of Klebsiella pneumoniae carbapenemase: unraveling the impact of amino acid substitutions on β-lactam susceptibility and the role of avibactam in… · PMID 40067047 · 62 records
• Diversity of function in the isocitrate lyase enzyme superfamily: the Dianthus caryophyllus petal death protein cleaves alpha-keto and alpha-hydroxycarboxylic acids · PMID 16342929 · 16 records
• Diversity of properties among catalases · PMID 12054464 · 32 records
• DNA family shuffling of hyperthermostable beta-glycosidases · PMID 12164784 · 20 records
• DNA Repair Exhaustion Activates Orthocaspase-Mediated Cell Death and Promote Inclusive Fitness of Cyanobacterial Population Under Abiotic Stress · PMID 42304937 · 2 records
• Do cysteine 230 and lysine 238 of biotin carboxylase play a role in the activation of biotin? · PMID 10747803 · 11 records
• Domain dissection and characterization of the aminoglycoside resistance enzyme ANT(3″)-Ii/AAC(6')-IId from Serratia marcescens · PMID 23485681 · 34 records
• Domain swapping in the cytoplasmic domain of the Escherichia coli rhomboid protease · PMID 23353827 · 14 records
• Domain-domain interactions in the aminoglycoside antibiotic resistance enzyme AAC(6')-APH(2'') · PMID 15274639 · 29 records
• Domain-specific determinants of catalysis/substrate binding and the oligomerization status of barley UDP-glucose pyrophosphorylase · PMID 19683599 · 28 records
• Dominant negative role of the glutamic acid residue conserved in the pyruvate kinase M(1) isozyme in the heterotropic allosteric effect involving fructose-1,6-bisphosphate · PMID 10734049 · 8 records
• Donor-induced conformational gating and substrate-assisted catalysis in α-1,3-galactosyltransferase · PMID 42603117 · 16 records
• Double function hydroperoxide lyases/epoxyalcohol synthases (CYP74C) of higher plants: identification and conversion into allene oxide synthases by site-directed mutagenesis · PMID 29325723 · 30 records
• DR0022 from Deinococcus radiodurans is an acid uracil-DNA glycosylase · PMID 35607831 · 7 records
• Dramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis · PMID 15863831 · 42 records
• Dramatically improved catalytic activity of an artificial (S)-selective arylmalonate decarboxylase by structure-guided directed evolution · PMID 21559536 · 6 records
• Drosophila melanogaster angiotensin I-converting enzyme expressed in Pichia pastoris resembles the C domain of the mammalian homologue and does not require glycosylation for secretion and enzymic… · PMID 8761461 · 6 records
• Drug-resistant HIV-1 proteases identify enzyme residues important for substrate selection and catalytic rate · PMID 9753473 · 86 records
• Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase · PMID 17124497 · 20 records
• Dual biosynthesis pathway for longer-chain polyamines in the hyperthermophilic archaeon Thermococcus kodakarensis · PMID 20675472 · 5 records
• Dual functional roles of ATP in the human mitochondrial malic enzyme · PMID 15182181 · 10 records
• Dual functionality of β-tryptase protomers as both proteases and cofactors in the active tetramer · PMID 29661938 · 5 records
• Dual regulatory switch confers tighter control on HtrA2 proteolytic activity · PMID 24698088 · 4 records
• Dual role of cysteine 172 in redox regulation of ribulose 1,5-bisphosphate carboxylase/oxygenase activity and degradation · PMID 12591867 · 10 records
• Dual role of the active site 'lid' regions of protochlorophyllide oxidoreductase in photocatalysis and plant development · PMID 32866986 · 20 records
• Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in alpha-aminoadipate aminotransferase from Thermus thermophilus · PMID 19632206 · 25 records
• Dual specificity and novel structural folding of yeast phosphodiesterase-1 for hydrolysis of second messengers cyclic adenosine and guanosine 3',5'-monophosphate · PMID 25050706 · 36 records
• Duck liver 'malic' enzyme. Expression in Escherichia coli and characterization of the wild-type enzyme and site-directed mutants · PMID 1622402 · 8 records
• Duodenase, a new serine protease of unusual specificity from bovine duodenal mucosa. Purification and properties · PMID 7867648 · 7 records
• Duplication of teichoic acid biosynthetic genes in Staphylococcus aureus leads to functionally redundant poly(ribitol phosphate) polymerases · PMID 18556787 · 4 records
• DXP synthase-catalyzed C-N bond formation: nitroso substrate specificity studies guide selective inhibitor design · PMID 23824585 · 19 records
• Dynamic diversification of lignan metabolism in sesame via coordinated oxygenation and glucosylation across germination · PMID 42247565 · 19 records
• Dynamic kinetic resolution of amino acid amide catalyzed by D-aminopeptidase and alpha-amino-epsilon-caprolactam racemase · PMID 15913357 · 5 records
• Dynamin GTPase domain mutants that differentially affect GTP binding, GTP hydrolysis, and clathrin-mediated endocytosis · PMID 15262989 · 20 records
• DyP-like peroxidases of the jelly fungus Auricularia auricula-judae oxidize nonphenolic lignin model compounds and high-redox potential dyes · PMID 19756587 · 12 records
• E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical… · PMID 18160520 · 18 records
• E461H-beta-galactosidase (Escherichia coli): altered divalent metal specificity and slow but reversible metal inactivation · PMID 7577931 · 20 records
• Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function · PMID 20435888 · 18 records
• Early occurrence of caffeoylshikimic acid esterase (CSE) activity in the hornwort Anthoceros agrestis · PMID 41493499 · 5 records
• Ectoine hydroxylase displays selective trans-3-hydroxylation activity towards L-proline · PMID 31106391 · 4 records
• Effect of a disulfide bond on mevalonate kinase · PMID 17964869 · 16 records
• Effect of a mutagenized acyl-ACP thioesterase FATA allele from sunflower with improved activity in tobacco leaves and Arabidopsis seeds · PMID 24327259 · 20 records
• Effect of amines as activators on the alcohol-oxidizing activity of pyrroloquinoline quinone-dependent quinoprotein alcohol dehydrogenase · PMID 25229857 · 2 records
• Effect of an amino acid insertion into the omega loop region of a class C beta-lactamase on its substrate specificity · PMID 9671516 · 35 records
• Effect of an oxygen-tolerant bifurcating butyryl coenzyme A dehydrogenase/electron-transferring flavoprotein complex from Clostridium difficile on butyrate production in Escherichia coli · PMID 23772070 · 11 records
• Effect of Leu²⁷⁷ on Disproportionation and Hydrolysis Activity in Bacillus stearothermophilus NO2 Cyclodextrin Glucosyltransferase · PMID 33837009 · 18 records
• Effect of loop-grafting on the activity, stability and regioselectivity of Priestia megaterium levansucrase using two inulosucrases as loop donors · PMID 40023420 · 13 records
• Effect of modified nucleotides on Escherichia coli tRNAGlu structure and on its aminoacylation by glutamyl-tRNA synthetase. Predominant and distinct roles of the mnm5 and s2 modifications of U34 · PMID 10583410 · 5 records
• Effect of pH and buffer on substrate binding and catalysis by cis-aconitate decarboxylase · PMID 39934230 · 35 records
• Effect of single-site charge-reversal mutations on the catalytic properties of yeast cytochrome c peroxidase: mutations near the high-affinity cytochrome c binding site · PMID 17580971 · 15 records
• Effect of site-directed mutagenesis of the conserved aspartate and glutamate on E. coli undecaprenyl pyrophosphate synthase catalysis · PMID 11076526 · 10 records
• Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation · PMID 24771868 · 20 records
• Effect of the phosphate substrate on drug-inhibitor binding to human purine nucleoside phosphorylase · PMID 18938130 · 6 records
• Effect of wine inhibitors on free pineapple stem bromelain activity in a model wine system · PMID 21381670 · 13 records
• Effects of active site residues of 3α-hydroxysteroid dehydrogenase from pseudomonas sp. b-0831 on its catalysis and cofactor binding · PMID 29912635 · 13 records
• Effects of amines and aminoalcohols on bovine intestine alkaline phosphatase activity · PMID 22112405 · 47 records
• Effects of amino acid substitutions at positions 33 and 37 on UDP-glucuronosyltransferase 1A9 (UGT1A9) activity and substrate selectivity · PMID 22981363 · 36 records
• Effects of bienzyme complex formation of cysteine synthetase from escherichia coli on some properties and kinetics · PMID 10993149 · 14 records
• Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase · PMID 7910607 · 28 records
• Effects of elevated glucose concentrations on the metabolism of the aortic wall · PMID 4640951 · 22 records
• Effects of flavin-binding motif amino acid mutations in the NADH-cytochrome b5 reductase catalytic domain on protein stability and catalysis · PMID 11574067 · 22 records
• Effects of human SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of acetaminophen and opioid drugs by the cytosolic sulfotransferase SULT1A3 · PMID 29705271 · 52 records
• Effects of hydrogen bonds in association with flavin and substrate in flavoenzyme d-amino acid oxidase. The catalytic and structural roles of Gly313 and Thr317 · PMID 11754736 · 22 records
• Effects of inherited mutations on catalytic activity and structural stability of human glucose-6-phosphate isomerase expressed in Escherichia coli · PMID 19064002 · 15 records
• Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T · PMID 27720751 · 8 records
• Effects of isoleucine 135 side chain length on the cofactor donor-acceptor distance within F₄₂₀H₂:NADP⁺ oxidoreductase: A kinetic analysis · PMID 28955995 · 3 records
• Effects of magnesium ions on recombinant human furin: selective activation of hydrolytic activity upon substrates derived from virus envelope glycoprotein · PMID 20635860 · 51 records
• Effects of multiple ligand binding on kinetic isotope effects in PQQ-dependent methanol dehydrogenase · PMID 12667088 · 26 records
• Effects of mutation at methionine-42 of Escherichia coli dihydrofolate reductase on stability and function: implication of hydrophobic interactions · PMID 15944418 · 14 records
• Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase · PMID 11341926 · 27 records
• Effects of N(2)-alkylguanine, O(6)-alkylguanine, and abasic lesions on DNA binding and bypass synthesis by the euryarchaeal B-family DNA polymerase vent (exo(-)) · PMID 22793782 · 54 records
• Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin · PMID 3643848 · 45 records
• Effects of self-association of ornithine aminotransferase on its physicochemical characteristics · PMID 7470464 · 29 records
• Effects of several alcohols on glycosidase activities in rat liver and brain · PMID 1499277 · 45 records
• Effects of site-directed mutagenesis of Asn116 in the β-hairpin of the N-terminal domain of thermolysin on its activity and stability · PMID 22648563 · 25 records
• Effects of Substrate-Binding Site Residues on the Biochemical Properties of a Tau Class Glutathione S-Transferase from Oryza sativa · PMID 31878175 · 14 records
• Effects of the mutational combinations on the activity and stability of thermolysin · PMID 20214932 · 42 records
• Effects of TiO₂ nanoparticles on the kinetics and conformation of bovine alkaline phosphatase · PMID 42502275 · 4 records
• Effects on substrate profile by mutational substitutions at positions 164 and 179 of the class A TEM(pUC19) beta-lactamase from Escherichia coli · PMID 10438473 · 45 records
• Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4 · PMID 16306039 · 10 records
• Efficient Biotransformation of Zearalenone in Acidic Food Matrices by Alkaline Enzyme-Inorganic Hybrid Nanoflower · PMID 42188631 · 2 records
• Efficient glycosylation of polyphenols via dynamic complexation of cyclodextrin and synchronous coupling reaction with cyclodextrin glycosyltransferase in water · PMID 39353521 · 1 record
• Efficient screening for new amino acid dehydrogenase activity: directed evolution of Bacillus sphaericus phenylalanine dehydrogenase towards activity with an unsaturated non-natural amino acid · PMID 19501264 · 28 records
• Efficient Synthesis of Purine Nucleoside Analogs by a New Trimeric Purine Nucleoside Phosphorylase from Aneurinibacillus migulanus AM007 · PMID 31888088 · 3 records
• Efficient tryptophan-catabolizing activity is consistently conserved through evolution of TDO enzymes, but not IDO enzymes · PMID 25702628 · 5 records
• Efficient whole-cell biocatalytic synthesis of 2'-deoxy-2'-fluoroadenosine, a key building block for nucleic acid drugs · PMID 42179739 · 4 records
• EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides · PMID 22798687 · 12 records
• Eis, a novel family of arylalkylamine N-acetyltransferase (EC 2.3.1.87) · PMID 29402941 · 26 records
• Electrochemical Insight into the Copper Redox Chemistry and H2O2 and O2 Reducing Capability of Two AA10 Lytic Polysaccharide… · PMID 41669087 · 16 records
• Electron acceptor specificity of ferredoxin (flavodoxin):NADP+ oxidoreductase from Escherichia coli · PMID 12234497 · 4 records
• Electron transfer from quinohemoprotein alcohol dehydrogenase to blue copper protein azurin in the alcohol oxidase respiratory chain of Pseudomonas putida HK5 · PMID 10320337 · 5 records
• Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis · PMID 19228070 · 14 records
• Electrostatic Engineering of Phosphoketolase Enhances Activity on Small Nonphosphorylated Sugars and Improves Cell-Free ATP Regeneration from Inexpensive C2-Substrates · PMID 42560102 · 11 records
• Electrostatic Interactions Dictate Bile Salt Hydrolase Substrate Preference · PMID 37883888 · 10 records
• Electrostatic interactions play a significant role in the affinity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase for Mn2+ · PMID 20211682 · 32 records
• Electrostatic stabilization in a pre-organized polar active site: the catalytic role of Lys-80 in Candida tenuis xylose reductase (AKR2B5) probed by site-directed mutagenesis and functional… · PMID 15799715 · 4 records
• Electrostatic tuning of the pyridoxal-5'-phosphate cofactor site defines pH dependence in type I cystathionine β-lyases · PMID 42001944 · 15 records
• Elimination of a Free Cysteine by Creation of a Disulfide Bond Increases the Activity and Stability of Candida boidinii Formate Dehydrogenase · PMID 27836850 · 8 records
• Elucidating the biochemical properties of limonene synthase from Agastache rugosa · PMID 42420857 · 2 records
• Elucidation of a monovalent cation dependence and characterization of the divalent cation binding site of the fosfomycin resistance protein (FosA) · PMID 10360943 · 12 records
• Elucidation of active site residues of Arabidopsis thaliana flavonol synthase provides a molecular platform for engineering flavonols · PMID 17719613 · 6 records
• Elucidation of dimethyl sulfide assimilation in soil bacteria expands the enzymatic landscape of terrestrial sulfur cycling · PMID 42286912 · 13 records
• Elucidation of exo-beta-D-glucosaminidase activity of a family 9 glycoside hydrolase (PBPRA0520) from Photobacterium profundum SS9 · PMID 21098515 · 10 records
• Elucidation of the d-lysine biosynthetic pathway in the hyperthermophile Thermotoga maritima · PMID 30548096 · 10 records
• Elucidation of the key flavonol biosynthetic pathway in golden Camellia and its application in genetic modification of tomato fruit metabolism · PMID 39944987 · 6 records
• Elucidation of the role of Ser329 and the C-terminal region in the catalytic activity of Pseudomonas stutzeri L-rhamnose isomerase · PMID 20977999 · 18 records
• Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor · PMID 17709141 · 12 records
• Elucidation of the trigonelline degradation pathway reveals previously undescribed enzymes and metabolites · PMID 29686076 · 8 records
• Emergence of ceftazidime-avibactam resistance mediated by KPC variants KPC-71 and KPC-78 in ST463 Pseudomonas aeruginosa · PMID 42429474 · 11 records
• Emergence of Ceftazidime-Avibactam-Induced KPC Variants (KPC-25/127) in Intracranial Infection and Implications for Clinical Management · PMID 42385193 · 9 records
• Enantioselective Cascade Biocatalysis for Deracemization of Racemic β-Amino Alcohols to Enantiopure (S)-β-Amino Alcohols by Employing Cyclohexylamine Oxidase and ω-Transaminase · PMID 32789939 · 6 records
• Enantioselective Resolution of β- and γ-Lactams by a Single Amidase From Rhodococcus baikonurensis Enables Efficient Access to Key Intermediates for Paclitaxel and Carbocyclic Nucleosides · PMID 42503021 · 2 records
• Enantioselective substrate specificity of 15-lipoxygenase 1 · PMID 15595827 · 12 records
• Enantioselectivity of human AMP, dTMP and UMP-CMP kinases · PMID 17626051 · 24 records
• Endo-β-1,4-Xylanase GH10 from Geobacillus stearothermophilus CECT43: Biochemical Characterization, Insights into Its Thermal Behavior, and Synergistic Effects with a β-Xylosidase · PMID 42653343 · 5 records
• Endopeptidase 24.15 from rat testes. Isolation of the enzyme and its specificity toward synthetic and natural peptides, including enkephalin-containing peptides · PMID 2803255 · 12 records
• Engineered and Native Coenzyme B12-dependent Isovaleryl-CoA/Pivalyl-CoA Mutase · PMID 26134562 · 15 records
• Engineered Bacillus pumilus laccase-like multi-copper oxidase for enhanced oxidation of the lignin model compound guaiacol · PMID 28482039 · 9 records
• Engineered Citrobacter freundii methionine γ-lyase effectively produces antimicrobial thiosulfinates · PMID 27430732 · 17 records
• Engineered formate dehydrogenase from Chaetomium thermophilum, a promising enzymatic solution for biotechnical CO₂ fixation · PMID 32557118 · 9 records
• Engineered glycolytic glyceraldehyde-3-phosphate dehydrogenase binds the anti conformation of NAD+ nicotinamide but does not experience A-specific hydride transfer · PMID 10190977 · 15 records
• Engineered inhibitor sensitivity in the WPD loop of a protein tyrosine phosphatase · PMID 18358001 · 48 records
• Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli · PMID 21515217 · 18 records
• Engineered monomeric human histidine triad nucleotide-binding protein 1 hydrolyzes fluorogenic acyl-adenylate and lysyl-tRNA synthetase-generated lysyl-adenylate · PMID 17337452 · 10 records
• Engineered polymerase-mediated efficient synthesis of site-specifically functionalized RNA and 2'-modified RNA oligonucleotides via genetic alphabet expansion · PMID 42722644 · 18 records
• Engineering a domain-locking disulfide into a bacterial malate dehydrogenase produces a redox-sensitive enzyme · PMID 7647229 · 8 records
• Engineering a fungal peroxidase that degrades lignin at very acidic pH · PMID 25788979 · 22 records
• Engineering a monolignol 4-O-methyltransferase with high selectivity for the condensed lignin precursor coniferyl alcohol · PMID 26378240 · 6 records
• Engineering a norcoclaurine synthase for one-step synthesis of (S)-1-aryl-tetrahydroisoquinolines · PMID 38647611 · 4 records
• Engineering a substrate-specific cold-adapted subtilisin · PMID 15047911 · 10 records
• Engineering a thermostable Halothermothrix orenii β-glucosidase for improved galacto-oligosaccharide synthesis · PMID 26621798 · 12 records
• Engineering a thermostable highly active glucose 6-phosphate dehydrogenase and its application to hydrogen production in vitro · PMID 29480380 · 10 records
• Engineering a yeast cell factory for high-level production of unnatural ginsenoside 3β-O-Glc-DM · PMID 41731501 · 8 records
• Engineering acidic Streptomyces rubiginosus D-xylose isomerase by rational enzyme design · PMID 24402330 · 21 records
• Engineering an aldehyde dehydrogenase toward its substrates, 3-hydroxypropanal and NAD⁺, for enhancing the production of 3-hydroxypropionic acid · PMID 29214999 · 61 records
• Engineering an ATP-saving mevalonate pathway for high-efficiency S-(+)-linalool production in Serratia marcescens · PMID 42179738 · 2 records
• Engineering an enzyme by site-directed mutagenesis to be resistant to chemical oxidation · PMID 3922976 · 5 records
• Engineering and characterization of a NADPH-utilizing cytochrome b5 reductase · PMID 14503867 · 18 records
• Engineering and kinetic characterisation of two glucosyltransferases from Arabidopsis thaliana · PMID 18295607 · 8 records
• Engineering broad-spectrum digestion of polyuronides from an exolytic polysaccharide lyase · PMID 26913076 · 10 records
• Engineering catalytic properties and thermal stability of plant formate dehydrogenase by single-point mutations · PMID 23100543 · 8 records
• Engineering chimeric thermostable GH7 cellobiohydrolases in Saccharomyces cerevisiae · PMID 23974371 · 5 records
• Engineering Chondroitinase-Free Baculovirus-Insect Cell Expression System for Efficient Synthesis of Chondroitin Sulphates · PMID 42138055 · 3 records
• Engineering Cofactor Specificity of a Thermostable Phosphite Dehydrogenase for a Highly Efficient and Robust NADPH Regeneration System · PMID 33869158 · 20 records
• Engineering D-Lactate Dehydrogenase from Pediococcus acidilactici for Improved Activity on 2-Hydroxy Acids with Bulky C₃ Functional Group · PMID 31190286 · 14 records
• Engineering d-Lactate Dehydrogenase to Favor an Non-natural Cofactor Nicotinamide Cytosine Dinucleotide · PMID 32175634 · 10 records
• Engineering Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase for Fully Active Amidated NAD Biosynthesis · PMID 28455340 · 6 records
• Engineering galactoside acetyltransferase for enhanced hesperetin-7-O-glucoside bioavailability · PMID 41491277 · 3 records
• Engineering Herbicide-Tolerance Rice Expressing an Acetohydroxyacid Synthase with a Single Amino Acid Deletion · PMID 32070060 · 8 records
• Engineering human RNase 7 with an eosinophil RNase segment reveals determinants of cytotoxic and antimicrobial activity · PMID 42203172 · 2 records
• Engineering Klebsiella sp. 601 multicopper oxidase enhances the catalytic efficiency towards phenolic substrates · PMID 21624144 · 9 records
• Engineering methionine γ-lyase from Citrobacter freundii for anticancer activity · PMID 30268810 · 11 records
• Engineering mouse chymotrypsin B1 for improved trypsinogen degradation · PMID 40133496 · 6 records
• Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease · PMID 25089527 · 46 records
• Engineering of 10-Deacetylbaccatin III-10-β-O-Acetyltransferase From Taxus Species for Efficient Acetylating Non-Natural Substrates Into Taxol in Nicotiana benthamiana · PMID 41618615 · 19 records
• Engineering of a bacterial tyrosinase for improved catalytic efficiency towards D-tyrosine using random and site directed mutagenesis approaches · PMID 23381872 · 15 records
• Engineering of a borneol dehydrogenase from P. putida for the enzymatic resolution of camphor · PMID 33846823 · 8 records
• Engineering of a glycosidase Family 7 cellobiohydrolase to more alkaline pH optimum: the pH behaviour of Trichoderma reesei Cel7A and its E223S/ A224H/L225V/T226A/D262G mutant · PMID 11336632 · 12 records
• Engineering of Alicyclobacillus hesperidum L-arabinose isomerase for improved catalytic activity and reduced pH optimum using random and site-directed mutagenesis · PMID 26335445 · 12 records
• Engineering of anp efficient mutant of Neisseria polysaccharea amylosucrase for the synthesis of controlled size maltooligosaccharides · PMID 28732882 · 1 record
• Engineering of flavonoid 3'-O-methyltransferase for improved biosynthesis of chrysoeriol in Escherichia coli · PMID 36719434 · 6 records
• Engineering of glycerol dehydrogenase for improved activity towards 1, 3-butanediol · PMID 20585771 · 10 records
• Engineering of Helicobacter pylori L-asparaginase: characterization of two functionally distinct groups of mutants · PMID 25664771 · 7 records
• Engineering of LadA for enhanced hexadecane oxidation using random- and site-directed mutagenesis · PMID 22526792 · 10 records
• Engineering of Methionine Adenosyltransferase Reveals Key Roles of Electrostatic Interactions in Enhanced Catalytic Activity · PMID 37642924 · 13 records
• Engineering of pyranose dehydrogenase for increased oxygen reactivity · PMID 24614932 · 7 records
• Engineering of S2 site of aqualysin I; alteration of P2 specificity by excluding P2 side chain · PMID 9860855 · 13 records
• Engineering of the catalytic site of xylose isomerase to enhance bioconversion of a non-preferential substrate · PMID 22586153 · 6 records
• Engineering of the Flavone Rutinoside Biosynthetic Pathway Enables Production of Diosmin, a Venoactive Compound in Solanum lycopersicum and Nicotiana tabacum · PMID 41230737 · 10 records
• Engineering of the pH optimum of Bacillus cereus beta-amylase: conversion of the pH optimum from a bacterial type to a higher-plant type · PMID 15449941 · 7 records
• Engineering of the yeast antioxidant enzyme Mpr1 for enhanced activity and stability · PMID 19170243 · 20 records
• Engineering of trypsin and its impact on beta-casein processing · PMID 9739553 · 32 records
• Engineering polyethylenimine-metal functionalized cryogels for superior catalase binding, activity, and long-term durability · PMID 41663626 · 2 records
• Engineering PQQ glucose dehydrogenase with improved substrate specificity. Site-directed mutagenesis studies on the active center of PQQ glucose dehydrogenase · PMID 15113562 · 46 records
• Engineering pyranose 2-oxidase for modified oxygen reactivity · PMID 25296188 · 22 records
• Engineering Rubisco condensation in chloroplasts to manipulate plant photosynthesis · PMID 40087764 · 4 records
• Engineering Streptomyces clavuligerus deacetoxycephalosporin C synthase for optimal ring expansion activity toward penicillin G · PMID 12676714 · 16 records
• Engineering the acceptor specificity of trehalose phosphorylase for the production of trehalose analogs · PMID 22848048 · 42 records
• Engineering the active center of the 6-phospho-beta-galactosidase from Lactococcus lactis · PMID 10906347 · 11 records
• Engineering the cofactor specificity of an alcohol dehydrogenase via single mutations or insertions distal to the 2'-phosphate group of NADP(H) · PMID 28201792 · 28 records
• Engineering the enantioselectivity of glutathione transferase by combined active-site mutations and chemical modifications · PMID 17689871 · 101 records
• Engineering the expression and characterization of two novel laccase isoenzymes from Coprinus comatus in Pichia pastoris by fusing an additional ten amino acids tag at N-terminus · PMID 24710109 · 8 records
• Engineering the meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum by site saturation mutagenesis for D-phenylalanine synthesis · PMID 23728814 · 10 records
• Engineering the nucleotide coenzyme specificity and sulfhydryl redox sensitivity of two stress-responsive aldehyde dehydrogenase isoenzymes of Arabidopsis thaliana · PMID 21166653 · 28 records
• Engineering the respiratory complex I to energy-converting NADPH:ubiquinone oxidoreductase · PMID 21832062 · 10 records
• Engineering the substrate binding site of benzoylformate decarboxylase · PMID 19621900 · 20 records
• Engineering the substrate scope of the thermostable phenolic acid decarboxylase N31 towards sterically hindered phenolic acids · PMID 42438340 · 26 records
• Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase · PMID 19061385 · 24 records
• Engineering the substrate specificity of Alcaligenes D-aminoacylase useful for the production of D-amino acids by optical resolution · PMID 21546325 · 9 records
• Engineering the substrate specificity of D-amino-acid oxidase · PMID 12021281 · 19 records
• Engineering the substrate specificity of Escherichia coli asparaginase. II. Selective reduction of glutaminase activity by amino acid replacements at position 248 · PMID 11106175 · 33 records
• Engineering the substrate specificity of porcine kidney D-amino acid oxidase by mutagenesis of the "active-site lid" · PMID 16751595 · 44 records
• Engineering the substrate specificity of the Abl tyrosine kinase · PMID 9988744 · 35 records
• Engineering the substrate specificity of xylose isomerase · PMID 15713782 · 5 records
• Engineering the synthetic potential of β-lactam synthetase and the importance of catalytic loop dynamics · PMID 23616913 · 18 records
• Engineering the Turnover Stability of Cellobiose Dehydrogenase toward Long-Term Bioelectronic Applications · PMID 34306835 · 56 records
• Engineering the xenobiotic substrate specificity of maize glutathione S-transferase I · PMID 15556969 · 20 records
• Engineering yeast alcohol dehydrogenase. Replacing Trp54 by Leu broadens substrate specificity · PMID 8532667 · 22 records
• Engineering, characterization and phage display of hepatitis C virus NS3 protease and NS4A cofactor peptide as a single-chain protein · PMID 9930676 · 16 records
• Enhanced activity and substrate tolerance of 7α-hydroxysteroid dehydrogenase by directed evolution for 7-ketolithocholic acid production · PMID 30734123 · 4 records
• Enhanced catalytic efficiency and coenzyme affinity of leucine dehydrogenase by comprehensive screening strategy for L-tert-leucine synthesis · PMID 33929595 · 10 records
• Enhanced catalytic efficiency of CotA-laccase by DNA shuffling · PMID 31142180 · 2 records
• Enhanced cutinase-catalyzed hydrolysis of polyethylene terephthalate by covalent fusion to hydrophobins · PMID 25795674 · 8 records
• Enhanced expression and purification of fungal galactose oxidase in Escherichia coli and use for analysis of a saturation mutagenesis library · PMID 21264996 · 19 records
• Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from Arabidopsis · PMID 12913179 · 10 records
• Enhanced fructooligosaccharides synthesis by engineered Trichoderma atroviride β-fructofuranosidase · PMID 41795023 · 9 records
• Enhanced kinetic performance and stability of catalase immobilized on epoxy-functionalized kaolinite · PMID 41663741 · 2 records
• Enhanced maltose production through mutagenesis of acceptor binding subsite +2 in Bacillus stearothermophilus maltogenic amylase · PMID 26597712 · 6 records
• Enhanced Stability of Lactobacillus paracasei Aspartate Ammonia-Lyase via Electrospinning for Enzyme Immobilization · PMID 39940473 · 1 record
• Enhanced thermostability of nattokinase by rational design of disulfide bond · PMID 40033318 · 4 records
• Enhancement in the catalytic activity of Sulfolobus solfataricus P2 (+)-γ-lactamase by semi-rational design with the aid of a newly established high-throughput screening method · PMID 30310965 · 6 records
• Enhancement in the Catalytic Properties of CotA Laccase from Bacillus pumilus via High-Throughput Screening Using Malachite Green as a Pressure · PMID 40005745 · 5 records
• Enhancement of chymotrypsin-inhibitor/substrate interactions by 3 M NaCl · PMID 11342033 · 22 records
• Enhancement of isomerization activity and lactulose production of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus · PMID 27080880 · 5 records
• Enhancement of L-tryptophan 5-hydroxylation activity by structure-based modification of L-phenylalanine 4-hydroxylase from Chromobacterium violaceum · PMID 19664549 · 12 records
• Enhancement of the activity of horse liver alcohol dehydrogenase by modification of amino groups at the active sites · PMID 4314596 · 12 records
• Enhancement of the Brenneria sp. levansucrase thermostability by site-directed mutagenesis at Glu⁴⁰⁴ located at the "-TEAP-" residue motif · PMID 30503905 · 20 records
• Enhancement of the latent 3-isopropylmalate dehydrogenase activity of promiscuous homoisocitrate dehydrogenase by directed evolution · PMID 20735360 · 28 records
• Enhancement of thermal stability of chondroitinase ABC I by site-directed mutagenesis: an insight from Ramachandran plot · PMID 23159774 · 4 records
• Enhancing Bacillus cereus antibacterial ability through improved cofactor supply · PMID 40050842 · 8 records
• Enhancing prebiotic production by engineering the levanbiose-binding site of Erwinia tasmaniensis levansucrase · PMID 41769041 · 3 records
• Enhancing prediction accuracy for enzyme activity engineering through sequence co-evolution and epistatic relationship modeling · PMID 42708409 · 6 records
• Enhancing the activity and succinyl-CoA specificity of 3-ketoacyl-CoA thiolase Tfu_0875 through rational binding pocket engineering · PMID 38694995 · 16 records
• Enhancing the decolorization activity of Bacillus pumilus W3 CotA-laccase to Reactive Black 5 by site-saturation mutagenesis · PMID 32918582 · 12 records
• Enhancing the heat stability and kinetic parameters of the maize endosperm ADP-glucose pyrophosphorylase using iterative saturation mutagenesis · PMID 25600571 · 30 records
• Enhancing the latent nucleotide triphosphate flexibility of the glucose-1-phosphate thymidylyltransferase RmlA · PMID 17434871 · 14 records
• Enhancing the stability and catalytic efficiency of alkyl halide dehalogenase through poloxamer temperature-sensitive gel · PMID 40117280 · 2 records
• Enhancing the Thermostability of Bacillus licheniformis Alkaline Protease 2709 by Computation-Based Rational Design · PMID 40076384 · 15 records
• Enhancing the Thermostability of Feruloyl Esterase EstF27 by Directed Evolution and the Underlying Structural Basis · PMID 26329893 · 2 records
• Enhancing the Thermostability of Serratia plymuthica Sucrose Isomerase Using B-Factor-Directed Mutagenesis · PMID 26886729 · 4 records
• Entamoeba histolytica thioredoxin reductase: molecular and functional characterization of its atypical properties · PMID 22967759 · 28 records
• Enterococcus faecalis acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase, a dual-function protein of isopentenyl diphosphate biosynthesis · PMID 11914342 · 13 records
• Entropy effects on protein hinges: the reaction catalyzed by triosephosphate isomerase · PMID 15350130 · 6 records
• Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro · PMID 31214030 · 28 records
• Enzymatic activity and partial purification of solanapyrone synthase: first enzyme catalyzing Diels-Alder reaction · PMID 9659400 · 1 record
• Enzymatic activity and substrate specificity of mitogen-activated protein kinase p38alpha in different phosphorylation states · PMID 18669639 · 27 records
• Enzymatic activity and thermal stability of PEG-alpha-chymotrypsin conjugates · PMID 19224136 · 13 records
• Enzymatic Activity and Thermodynamic Stability of Biliverdin IXβ Reductase Are Maintained by an Active Site Serine · PMID 27897348 · 27 records
• Enzymatic activity assay of D-hydantoinase by isothermal titration calorimetry. Determination of the thermodynamic activation parameters for the hydrolysis of several substrates · PMID 16497383 · 22 records
• Enzymatic activity of Campylobacter jejuni hippurate hydrolase · PMID 16303789 · 11 records
• Enzymatic analysis of an amylolytic enzyme from the hyperthermophilic archaeon Pyrococcus furiosus reveals its novel catalytic properties as both an alpha-amylase and a cyclodextrin-hydrolyzing… · PMID 15466542 · 6 records
• Enzymatic and biochemical properties of a novel human serine dehydratase isoform · PMID 16580895 · 12 records
• Enzymatic and Mutational Analysis of the PruA Pteridine Reductase Required for Pterin-Dependent Control of Biofilm Formation in Agrobacterium tumefaciens · PMID 32482721 · 11 records
• Enzymatic and physiological properties of the tungsten-substituted molybdenum TMAO reductase from Escherichia coli · PMID 10216869 · 18 records
• Enzymatic and quantitative properties of Rubisco in C₃ herbaceous plants with early-spring persistent leaves and some alpine plants · PMID 41870733 · 15 records
• Enzymatic basis for N-glycan sialylation: structure of rat α2,6-sialyltransferase (ST6GAL1) reveals conserved and unique features for glycan sialylation · PMID 24155237 · 18 records
• Enzymatic Basis for the Oxidative Branch of Aromatic Amino Acid Fermentation Leading to p-cresol Formation · PMID 41915823 · 22 records
• Enzymatic characteristics and subcellular distribution of a short-chain dehydrogenase/reductase family protein, P26h, in hamster testis and epididymis · PMID 11141073 · 77 records
• Enzymatic characteristics of an aldo-keto reductase family protein (AKR1C15) and its localization in rat tissues · PMID 17574202 · 110 records
• Enzymatic characteristics of an ApaH-like phosphatase, PrpA, and a diadenosine tetraphosphate hydrolase, ApaH, from Myxococcus xanthus · PMID 25107648 · 9 records
• Enzymatic characteristics of cellobiose phosphorylase from Ruminococcus albus NE1 and kinetic mechanism of unusual substrate inhibition in reverse phosphorolysis · PMID 22484959 · 14 records
• Enzymatic characteristics of Nudix hydrolase 2 (Nud2), an 8-oxo-dGTP hydrolase from Myxococcus xanthus · PMID 31292314 · 14 records
• Enzymatic characteristics of two novel Myxococcus xanthus enzymes, PdeA and PdeB, displaying 3',5'- and 2',3'-cAMP phosphodiesterase, and phosphatase activities · PMID 19114044 · 8 records
• Enzymatic characterization and gene identification of aconitate isomerase, an enzyme involved in assimilation of trans-aconitic acid, from Pseudomonas sp. WU-0701 · PMID 26293748 · 4 records
• Enzymatic characterization of a monomeric isocitrate dehydrogenase from Streptomyces lividans TK54 · PMID 19631711 · 4 records
• Enzymatic characterization of a novel bovine liver dihydrodiol dehydrogenase--reaction mechanism and bile acid dehydrogenase activity · PMID 7766669 · 15 records
• Enzymatic characterization of AMP phosphorylase and ribose-1,5-bisphosphate isomerase functioning in an archaeal AMP metabolic pathway · PMID 23065974 · 5 records
• Enzymatic characterization of ancestral/group-IV clade xyloglucan endotransglycosylase/hydrolase enzymes reveals broad substrate specificities · PMID 33825243 · 10 records
• Enzymatic characterization of the recombinant Arabidopsis thaliana nitrilase subfamily encoded by the NIT2/NIT1/NIT3-gene cluster · PMID 11525507 · 18 records
• Enzymatic degradation of beta- and mixed alpha,beta-oligopeptides · PMID 17193247 · 8 records
• Enzymatic enantioselective decarboxylative protonation of heteroaryl malonates · PMID 25766433 · 29 records
• Enzymatic formation of prostaglandin F2 alpha from prostaglandin H2 and D2. Purification and properties of prostaglandin F synthetase from bovine lung · PMID 3858278 · 8 records
• Enzymatic Glucosylation Enhances the Solubility of Niclosamide but Abrogates Its Therapeutic Efficacy · PMID 41696203 · 4 records
• Enzymatic hydrolysis of PET: functional roles of three Ca²⁺ ions bound to a cutinase-like enzyme, Cut190*, and its engineering for improved activity · PMID 30250976 · 20 records
• Enzymatic Production of Prebiotic Xylooligosaccharides Using a Bacillus pumilus GH30_8 Glucuronoxylanase: Structural Basis of Glucuronoxylan Recognition and Hydrolysis · PMID 41632704 · 2 records
• Enzymatic properties of a thermostable α-glucosidase from acidothermophilic crenarchaeon Sulfolobus tokodaii strain 7 · PMID 23314368 · 9 records
• Enzymatic properties of mutant Escherichia coli tryptophan synthase alpha-subunits · PMID 1939081 · 88 records
• Enzymatic properties of the cysteinesulfinic acid derivative of the catalytic-base mutant Glu400-->Cys of glucoamylase from Aspergillus awamori · PMID 9521694 · 33 records
• Enzymatic properties of the glycine D-alanine [corrected] aminopeptidase of Aspergillus oryzae and its activity profiles in liquid-cultured mycelia and solid-state rice culture (rice koji) · PMID 22005737 · 3 records
• Enzymatic properties of the protein encoded by newly cloned human alcohol dehydrogenase ADH6 gene · PMID 1755855 · 3 records
• Enzymatic properties of UDP-glycosyltransferase 89B1 from radish and modulation of enzyme catalytic activity via loop region mutation · PMID 38416725 · 14 records
• ENZYMATIC SYNTHESIS OF ANALOGS OF THE CELL-WALL PRECURSOR. I. KINETICS AND SPECIFICITY OF URIDINE DIPHOSPHO-N-ACETYLMURAMYL-L-ALANYL-D-GLUTAMYL-L-LYSINE:D-ALANYL-D-ALANINE LIGASE (ADENOSINE… · PMID 14285229 · 22 records
• Enzymatic synthesis of model substrates recognized by glucuronoyl esterases from Podospora anserina and Myceliophthora thermophila · PMID 24531271 · 6 records
• Enzymatic versatility and thermostability of a new aryl-alcohol oxidase from Thermothelomyces thermophilus M77 · PMID 32653619 · 4 records
• Enzyme Architecture: A Startling Role for Asn270 in Glycerol 3-Phosphate Dehydrogenase-Catalyzed Hydride Transfer · PMID 26926520 · 4 records
• Enzyme architecture: deconstruction of the enzyme-activating phosphodianion interactions of orotidine 5'-monophosphate decarboxylase · PMID 24958125 · 10 records
• Enzyme architecture: the effect of replacement and deletion mutations of loop 6 on catalysis by triosephosphate isomerase · PMID 24825099 · 7 records
• Enzyme catalysis via control of activation entropy: site-directed mutagenesis of 6,7-dimethyl-8-ribityllumazine synthase · PMID 12581640 · 37 records
• Enzyme Characterization of Pro-virulent SntA, a Cell Wall-Anchored Protein of Streptococcus suis, With Phosphodiesterase Activity on cyclic-di-AMP at a Level Suited to Limit the Innate Immune… · PMID 35391727 · 62 records
• Enzyme I of the phosphotransferase system: induced-fit protonation of the reaction transition state by Cys-502 · PMID 12705838 · 17 records
• Enzyme kinetics of dUTPase from the planarian Dugesia ryukyuensis · PMID 30902068 · 6 records
• Enzyme structure and kinetics produce tRNA and nucleotide specificity of Schizosaccharomyces pombe CC- and A-adding enzymes · PMID 42130072 · 6 records
• Enzyme-catalysed synthesis of pyridines from biomass-derived feedstocks · PMID 42300662 · 3 records
• Enzyme-catalyzed acylation of homoserine: mechanistic characterization of the Escherichia coli metA-encoded homoserine transsuccinylase · PMID 10572016 · 9 records
• Enzyme-catalyzed acylation of homoserine: mechanistic characterization of the Haemophilus influenzae met2-encoded homoserine transacetylase · PMID 10913262 · 14 records
• Enzyme-catalyzed oxidation of 5-hydroxymethylfurfural to furan-2,5-dicarboxylic acid · PMID 24802551 · 3 records
• Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination · PMID 23929881 · 8 records
• Enzyme-substrate interaction and characterization of a 2,3-dihydroxybiphenyl 1,2-dioxygenase from Dyella ginsengisoli LA-4 · PMID 19187202 · 5 records
• Enzymes encoded by the farnesyl diphosphate synthase gene family in the Big Sagebrush Artemisia tridentata ssp. spiciformis · PMID 12782626 · 8 records
• Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina · PMID 16930134 · 21 records
• Enzymes of mannitol metabolism in the human pathogenic fungus Aspergillus fumigatus--kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological… · PMID 21299839 · 22 records
• Enzymological characterization of the signal-transducing uridylyltransferase/uridylyl-removing enzyme (EC 2.7.7.59) of Escherichia coli and its interaction with the PII protein · PMID 9737855 · 15 records
• Enzymology and evolution of the pyruvate pathway to 2-oxobutyrate in Methanocaldococcus jannaschii · PMID 17449626 · 9 records
• Enzymology and structure of the GH13_31 glucan 1,6-α-glucosidase that confers isomaltooligosaccharide utilization in the probiotic Lactobacillus acidophilus NCFM · PMID 22685275 · 6 records
• Epoxidation of linear, branched and cyclic alkenes catalyzed by unspecific peroxygenase · PMID 23608506 · 1 record
• EPR spectroscopy reveals glycerol-dependent activation of cysteamine dioxygenase (ADO) enables bidentate substrate coordination · PMID 41985785 · 6 records
• Epsilonproteobacterial hydroxylamine oxidoreductase (εHao): characterization of a 'missing link' in the multihaem cytochrome c family · PMID 28388834 · 16 records
• Erythrocyte adenylate kinase deficiency: characterization of recombinant mutant forms and relationship with nonspherocytic hemolytic anemia · PMID 17662886 · 12 records
• Escherichia coli alanyl-tRNA synthetase maintains proofreading activity and translational accuracy under oxidative stress · PMID 35065077 · 12 records
• Escherichia coli cystathionine gamma-synthase does not obey ping-pong kinetics. Novel continuous assays for the elimination and substitution reactions · PMID 14503880 · 14 records
• Escherichia coli cytosine deaminase: the kinetics and thermodynamics for binding of cytosine to the apoenzyme and the Zn(2+) holoenzyme are similar · PMID 10669789 · 13 records
• Escherichia coli dihydropyrimidine dehydrogenase is a novel NAD-dependent heterotetramer essential for the production of 5,6-dihydrouracil · PMID 21169495 · 4 records
• Escherichia coli DNA adenine methyltransferase: the structural basis of processive catalysis and indirect read-out · PMID 19419959 · 13 records
• Escherichia coli gamma-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding · PMID 11675389 · 46 records
• Escherichia coli tryptophanyl-tRNA synthetase mutants selected for tryptophan auxotrophy implicate the dimer interface in optimizing amino acid binding · PMID 8555191 · 43 records
• Escherichia coli YqhD exhibits aldehyde reductase activity and protects from the harmful effect of lipid peroxidation-derived aldehydes · PMID 18211903 · 5 records
• Essential biochemical, biophysical and computational inputs on efficient functioning of Mycobacterium tuberculosis H₃₇Rv FtsY · PMID 33412199 · 17 records
• Essential features of the catalytic core of peptidyl-alpha-hydroxyglycine alpha-amidating lyase · PMID 12369828 · 7 records
• Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosis · PMID 21153518 · 20 records
• Essential Role for an M17 Leucine Aminopeptidase in Encystation of Acanthamoeba castellanii · PMID 26075721 · 3 records
• Essential role of amino acid position 226 in oligosaccharide elongation by amylosucrase from Neisseria polysaccharea · PMID 24801911 · 10 records
• Essential role of amino acid position 71 in substrate preference by meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum IAM14863 · PMID 29421037 · 24 records
• Essential role of arginine 235 in the substrate-binding of Lactobacillus plantarum D-lactate dehydrogenase · PMID 7961609 · 10 records
• Essential role of histidine 20 in the catalytic mechanism of Escherichia coli peptidyl-tRNA hydrolase · PMID 15078105 · 11 records
• Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure · PMID 19780817 · 7 records
• Essential Role of the Linker Region in the Higher Catalytic Efficiency of a Bifunctional MsrA-MsrB Fusion Protein · PMID 27551953 · 14 records
• EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol · PMID 18223037 · 7 records
• Establishment of an in vitro D-cycloserine-synthesizing system by using O-ureido-L-serine synthase and D-cycloserine synthetase found in the biosynthetic pathway · PMID 23529730 · 18 records
• Establishment of mesophilic-like catalytic properties in a thermophilic enzyme without affecting its thermal stability · PMID 31249343 · 30 records
• Esters of mandelic acid as substrates for (S)-mandelate dehydrogenase from Pseudomonas putida: implications for the reaction mechanism · PMID 14967029 · 10 records
• Ethylmalonyl-CoA decarboxylase, a new enzyme involved in metabolite proofreading · PMID 22016388 · 4 records
• Eukaryotic and bacterial gene clusters related to an alternative pathway of nonphosphorylated L-rhamnose metabolism · PMID 18505728 · 19 records
• Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis · PMID 41441790 · 3 records
• Evaluation and Comparison of Candida albicans vs Mammalian 6-O-Phospho-Kinases: Substrate Specificity and Applications · PMID 39661445 · 6 records
• Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase · PMID 14555658 · 11 records
• Evaluation by site-directed mutagenesis of aspartic acid residues in the metal site of pig heart NADP-dependent isocitrate dehydrogenase · PMID 10694384 · 10 records
• Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2… · PMID 12920168 · 16 records
• Evaluation of substrate promiscuity of an L-carbamoyl amino acid amidohydrolase from Geobacillus stearothermophilus CECT43 · PMID 20730754 · 15 records
• Evaluation of the catalytic specificity, biochemical properties, and milk clotting abilities of an aspartic peptidase from Rhizomucor miehei · PMID 27165660 · 84 records
• Evaluation of the roles of hydrophobic residues in the N-terminal region of archaeal trehalase in its folding · PMID 33791835 · 10 records
• Evidence for an essential serine residue in the active site of the Theta class glutathione transferases · PMID 7575461 · 6 records
• Evidence for catalytic roles for Plasmodium falciparum aminopeptidase P in the food vacuole and cytosol · PMID 19574214 · 7 records
• Evidence for cysteine persulfide as reaction product of L-Cyst(e)ine C-S-lyase (C-DES) from Synechocystis. Analyses using cystine analogues and recombinant C-DES · PMID 9867829 · 9 records
• Evidence for differential folding of farnesyl pyrophosphate in the active site of aristolochene synthase: a single-point mutation converts aristolochene synthase into an (E)-beta-farnesene synthase · PMID 12820883 · 2 records
• Evidence for lysine 80 as general base catalyst of leucine dehydrogenase · PMID 8262941 · 25 records
• Evidence for the mechanism of hydroxylation by 4-hydroxyphenylpyruvate dioxygenase and hydroxymandelate synthase from intermediate partitioning in active site variants · PMID 21815644 · 9 records
• Evidence for the negative cooperativity of the two active sites within bovine somatic angiotensin-converting enzyme · PMID 12935891 · 11 records
• Evidence for two different mechanisms triggering the change in quaternary structure of the allosteric enzyme, glucosamine-6-phosphate deaminase · PMID 15667206 · 14 records
• Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments · PMID 11722566 · 21 records
• Evidence of a plasmid-encoded oxidative xylose-catabolic pathway in Arthrobacter nicotinovorans pAO1 · PMID 23063486 · 12 records
• Evidence of the participation of remote residues in the catalytic activity of Co-type nitrile hydratase from Pseudomonas putida · PMID 21473592 · 11 records
• Evidence of two functionally distinct ornithine decarboxylation systems in lactic acid bacteria · PMID 22247134 · 9 records
• Evidence that GH115 α-glucuronidase activity, which is required to degrade plant biomass, is dependent on conformational flexibility · PMID 24214982 · 29 records
• Evidence that glutamine transaminase and omega-amidase potentially act in tandem to close the methionine salvage cycle in bacteria and plants · PMID 24837359 · 6 records
• Evidence that human histidine triad nucleotide binding protein 3 (Hint3) is a distinct branch of the histidine triad (HIT) superfamily · PMID 17870088 · 12 records
• Evidence that the gene YLR070c of Saccharomyces cerevisiae encodes a xylitol dehydrogenase · PMID 10486580 · 6 records
• Evolution and biochemistry of family 4 glycosidases: implications for assigning enzyme function in sequence annotations · PMID 19625389 · 10 records
• Evolution and Functional Diversification of Serine Racemase Homologs in Bacteria · PMID 39821316 · 60 records
• Evolution of alcohol oxidase for improved methanol bioconversion and formaldehyde tolerance · PMID 42376006 · 4 records
• Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli · PMID 9772162 · 9 records
• Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli · PMID 10769114 · 19 records
• Evolution of enzymatic activities in the enolase superfamily: D-tartrate dehydratase from Bradyrhizobium japonicum · PMID 17144653 · 5 records
• Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli · PMID 11513584 · 9 records
• Evolution of enzymatic activities in the enolase superfamily: L-fuconate dehydratase from Xanthomonas campestris · PMID 17144652 · 10 records
• Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase · PMID 18754693 · 12 records
• Evolution of enzymatic activities in the enolase superfamily: N-succinylamino acid racemase and a new pathway for the irreversible conversion of D- to L-amino acids · PMID 16584181 · 40 records
• Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: mechanistic evidence for a proton relay system in the active site of 3-keto-L-gulonate 6-phosphate… · PMID 15157077 · 23 records
• Evolution of enzymatic activity in the enolase superfamily: functional studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis · PMID 14705949 · 12 records
• Evolution of Glucose Dehydrogenase for Cofactor Regeneration in Bioredox Processes with Denaturing Agents · PMID 32324965 · 7 records
• Evolution of lactate dehydrogenase-A homologs of barracuda fishes (genus Sphyraena) from different thermal environments: differences in kinetic properties and thermal stability are due to amino acid… · PMID 9115998 · 13 records
• Evolution of the adhE gene product of Escherichia coli from a functional reductase to a dehydrogenase. Genetic and biochemical studies of the mutant proteins · PMID 10922373 · 6 records
• Evolution of vertebrate indoleamine 2,3-dioxygenases · PMID 18026683 · 11 records
• Evolutional design of a hyperactive cysteine- and methionine-free mutant of Escherichia coli dihydrofolate reductase · PMID 16510443 · 22 records
• Evolutionarily Distinct BAHD N-Acyltransferases Are Responsible for Natural Variation of Aromatic Amine Conjugates in Rice · PMID 27354554 · 26 records
• Evolutionary and Functional Analysis of Monoamine Oxidase F: A Novel Member of the Monoamine Oxidase Gene Family · PMID 39749937 · 24 records
• Evolutionary conserved N-terminal region of human muscle fructose 1,6-bisphosphatase regulates its activity and the interaction with aldolase · PMID 18214967 · 9 records
• Evolutionary divergence of sedoheptulose 7-phosphate cyclases leads to several distinct cyclic products · PMID 22741921 · 5 records
• Evolutionary potential of (beta/alpha)8-barrels: in vitro enhancement of a "new" reaction in the enolase superfamily · PMID 16128573 · 13 records
• Evolutionary, computational, and biochemical studies of the salicylaldehyde dehydrogenases in the naphthalene degradation pathway · PMID 28233868 · 17 records
• Evolving transpeptidase and hydrolytic variants of γ-glutamyl transpeptidase from Bacillus licheniformis by targeted mutations of conserved residue Arg109 and their biotechnological relevance · PMID 28365292 · 12 records
• Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase · PMID 18342015 · 11 records
• Examination of substrate binding in thiamin diphosphate-dependent transketolase by protein crystallography and site-directed mutagenesis · PMID 8999873 · 12 records
• Examination of the thiamin diphosphate binding site in yeast transketolase by site-directed mutagenesis · PMID 9119035 · 8 records
• Examining the role of intersubunit contacts in catalysis by 3-deoxy-d-manno-octulosonate 8-phosphate synthase · PMID 23746359 · 13 records
• Exchange of active site residues alters substrate specificity in extremely thermostable β-glycosidase from Thermococcus kodakarensis KOD1 · PMID 26138395 · 6 records
• Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida · PMID 15930043 · 37 records
• Excision of products of oxidative DNA base damage by human NTH1 protein · PMID 9890904 · 39 records
• Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization… · PMID 12917011 · 19 records
• Expanding coincident signaling by PTEN through its inositol 1,3,4,5,6-pentakisphosphate 3-phosphatase activity · PMID 11418101 · 4 records
• Expanding knowledge of the Rubisco kinetics variability in plant species: environmental and evolutionary trends · PMID 24689692 · 68 records
• Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity · PMID 11959984 · 53 records
• Expanding the laccase-toolbox: a laccase from Corynebacterium glutamicum with phenol coupling and cuprous oxidase activity · PMID 24910971 · 4 records
• Expanding the substrate scope of phenylalanine ammonia-lyase from Petroselinum crispum towards styrylalanines · PMID 28405665 · 16 records
• Expanding tRNA recognition of a tRNA synthetase by a single amino acid change · PMID 12730374 · 7 records
• Expanding Yarrowia lipolytica's metabolic potential for detoxification of cyanogenic glycosides in edible plants · PMID 39915589 · 15 records
• Expansion of substrate specificity of cytochrome P450 2A6 by random and site-directed mutagenesis · PMID 16215230 · 51 records
• Expansion of the active site of the azoreductase from Shewanella oneidensis MR-1 · PMID 29100166 · 18 records
• Expansion of the Substrate Specificity of Porcine Kidney D-Amino Acid Oxidase for S-Stereoselective Oxidation of 4-Cl-Benzhydrylamine · PMID 30333894 · 17 records
• Experimental and computational investigation of enzyme functional annotations uncovers misannotation in the EC 1.1.3.15 enzyme class · PMID 34555022 · 5 records
• Experimental and computational studies on the unusual substrate specificity of branched-chain amino acid aminotransferase from Thermoproteus uzoniensis · PMID 27523731 · 4 records
• Experimentally Dissecting the Origins of Peroxiredoxin Catalysis · PMID 28375740 · 11 records
• Exploration of human xylosyltransferase for chemoenzymatic synthesis of proteoglycan linkage region · PMID 33899899 · 7 records
• Exploration of structure-function relationships in Escherichia coli cystathionine γ-synthase and cystathionine β-lyase via chimeric constructs and site-specific substitutions · PMID 23470500 · 11 records
• Exploration of the active site of Escherichia coli cystathionine γ-synthase · PMID 22855027 · 46 records
• Exploration of the six tryptophan residues of Escherichia coli cystathionine β-lyase as probes of enzyme conformational change · PMID 23969077 · 18 records
• Exploration of urease-aided calcium carbonate mineralization by enzyme analyses of Neobacillus mesonae strain NS-6 · PMID 39611830 · 4 records
• Exploring allosteric activation of LigAB from Sphingobium sp. strain SYK-6 through kinetics, mutagenesis and computational studies · PMID 25562402 · 8 records
• Exploring biochemical and functional features of Leishmania major phosphoenolpyruvate carboxykinase · PMID 26271440 · 20 records
• Exploring structural motifs necessary for substrate binding in the active site of Escherichia coli pantothenate kinase · PMID 24814884 · 28 records
• Exploring substrate binding and discrimination in fructose1, 6-bisphosphate and tagatose 1,6-bisphosphate aldolases · PMID 10712619 · 37 records
• Exploring the active site of tripeptidyl-peptidase II through studies of pH dependence of reaction kinetics · PMID 22266401 · 61 records
• Exploring the biochemical and biological functions of copper radical oxidases in the vascular wilt phytopathogen Verticillium dahliae · PMID 42233674 · 24 records
• Exploring the dihydrodipicolinate synthase tetramer: how resilient is the dimer-dimer interface? · PMID 19919824 · 16 records
• Exploring the evolutionary route of the acquisition of betaine aldehyde dehydrogenase activity by plant ALDH10 enzymes: implications for the synthesis of the osmoprotectant glycine betaine · PMID 24884441 · 28 records
• Exploring the Potential of Glutathione Reductase Overexpression to Improve Tellurium Nanoparticle Production in Escherichia coli · PMID 40004015 · 8 records
• Exploring the role of L209 residue in the active site of NDM-1 a metallo-β-lactamase · PMID 29293526 · 7 records
• Exploring the role of the active site cysteine in human muscle creatine kinase · PMID 16981706 · 20 records
• Exploring the sequence diversity in glycoside hydrolase family 13_18 reveals a novel glucosylglycerol phosphorylase · PMID 29470619 · 4 records
• Exploring the Structure-Function Relationships in a 5-Aminolevulinic Acid Synthase and the Use of Protein Engineering to Expand its Substrate Range · PMID 39688068 · 21 records
• Exploring the substrate promiscuity of drug-modifying enzymes for the chemoenzymatic generation of N-acylated aminoglycosides · PMID 19899089 · 43 records
• Exploring the synergy between fungal CE15 glucuronoyl esterases and xylanases for lignocellulose saccharification · PMID 40140928 · 2 records
• Expression and characterization of a Mycoplasma genitalium glycosyltransferase in membrane glycolipid biosynthesis: potential target against mycoplasma infections · PMID 21835921 · 6 records
• Expression and characterization of a novel β-glucosidase, with transglycosylation and exo-β-1,3-glucanase activities, from Rhizomucor miehei · PMID 25577102 · 8 records
• Expression and characterization of a thermostable penicillin G acylase from an environmental metagenomic library · PMID 24338159 · 9 records
• Expression and characterization of an extremely thermostable β-glycosidase (mannosidase) from the hyperthermophilic archaeon Pyrococcus furiosus DSM3638 · PMID 21624508 · 8 records
• Expression and characterization of Aspergillus thermostable phytases in Pichia pastoris · PMID 19025560 · 6 records
• Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite… · PMID 9578563 · 14 records
• Expression and characterization of human tissue kallikrein variants · PMID 9535704 · 12 records
• Expression and characterization of recombinant human angiotensin I-converting enzyme. Evidence for a C-terminal transmembrane anchor and for a proteolytic processing of the secreted recombinant and… · PMID 1848554 · 7 records
• Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular… · PMID 9415401 · 11 records
• Expression and characterization of the genes encoding azoreductases from Bacillus subtilis and Geobacillus stearothermophilus · PMID 16861800 · 6 records
• Expression and characterization of the human 3 beta-hydroxysteroid sulfotransferases (SULT2B1a and SULT2B1b) · PMID 11457664 · 15 records
• Expression and characterization of two functional methionine aminopeptidases from Mycobacterium tuberculosis H37Rv · PMID 19688379 · 4 records
• Expression and enzymatic properties of rice (Oryza sativa L.) monolignol β-glucosidases · PMID 25219312 · 20 records
• Expression and purification of aspartate beta-semialdehyde dehydrogenase from infectious microorganisms · PMID 12071715 · 12 records
• Expression and purification of the 5'-nucleotidase YitU from Bacillus species: its enzymatic properties and possible applications in biotechnology · PMID 32040605 · 9 records
• Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity · PMID 8099587 · 6 records
• Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate · PMID 9188497 · 14 records
• Expression in Escherichia coli of UDP-glucose pyrophosphorylase cDNA from potato tuber and functional assessment of the five lysyl residues located at the substrate-binding site · PMID 1909568 · 24 records
• Expression of a secretory α-glucosidase II from Apis cerana indica in Pichia pastoris and its characterization · PMID 23419073 · 6 records
• Expression of feruloyl esterase A from Aspergillus terreus and its application in biomass degradation · PMID 26282562 · 3 records
• Expression of human electron transfer flavoprotein-ubiquinone oxidoreductase from a baculovirus vector: kinetic and spectral characterization of the human protein · PMID 12049629 · 9 records
• Expression of Human β3GalT5-1 in Insect Cells as Active Glycoforms for the Efficient Synthesis of Cancer-Associated Globo-Series Glycans · PMID 40130300 · 15 records
• Expression of mouse uterine peptidylarginine deiminase in Escherichia coli: construction of expression plasmid and properties of the recombinant enzyme · PMID 7872804 · 16 records
• Expression of Novel L-Leucine Dehydrogenase and High-Level Production of L-Tert-Leucine Catalyzed by Engineered Escherichia coli · PMID 33859982 · 4 records
• Expression of peptidylarginine deiminase from Porphyromonas gingivalis in Escherichia coli: enzyme purification and characterization · PMID 19545534 · 14 records
• Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases. Isolation and characterization of the… · PMID 7887915 · 11 records
• Expression of Talaromyces emersonii cellobiohydrolase Cel7A in Saccharomyces cerevisiae and rational mutagenesis to improve its thermostability and activity · PMID 19951999 · 6 records
• Expression, Characterization and Selective Chemical Inhibition of Essential Schistosoma mansoni Tegumental Acetylcholinesterase (SmTAChE) · PMID 40076600 · 4 records
• Expression, characterization and structural modelling of a feruloyl esterase from the thermophilic fungus Myceliophthora thermophila · PMID 22012339 · 12 records
• Expression, characterization, and site-specific covalent immobilization of an L-amino acid oxidase from the fungus Hebeloma cylindrosporum · PMID 30631897 · 8 records
• Expression, crystallization and preliminary crystallographic analysis of human carbonyl reductase · PMID 7990149 · 10 records
• Expression, purification and catalytic activity of Lupinus luteus asparagine beta-amidohydrolase and its Escherichia coli homolog · PMID 15265041 · 4 records
• Expression, purification and characterization of GDP-D-mannose 4,6-dehydratase from Escherichia coli · PMID 9257704 · 1 record
• Expression, purification, and biochemical characterization of WbpP, a new UDP-GlcNAc C4 epimerase from Pseudomonas aeruginosa serotype O6 · PMID 10747995 · 4 records
• Expression, Purification, and Characterization of a Well-Adapted Tyrosinase from Peatlands Identified by Partial Community Analysis · PMID 34156250 · 8 records
• Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium · PMID 15122913 · 30 records
• Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes · PMID 16854592 · 9 records
• Expression, purification, and characterization of human type II arginase · PMID 11370664 · 3 records
• Expression, purification, and characterization of inosine 5'-monophosphate dehydrogenase from Borrelia burgdorferi · PMID 9268334 · 2 records
• Expression, purification, and characterization of mouse glycine N-acyltransferase in Escherichia coli · PMID 24576660 · 7 records
• Expression, purification, and characterization of Mycobacterium tuberculosis mycothione reductase · PMID 10512639 · 15 records
• Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis · PMID 10625657 · 7 records
• Expression, purification, and characterization of recombinant amorpha-4,11-diene synthase from Artemisia annua L · PMID 15797234 · 9 records
• Expression, purification, and characterization of the protein repair l-isoaspartyl methyltransferase from Arabidopsis thaliana · PMID 11049748 · 6 records
• Expression, purification, and characterization of the yeast KEX1 gene product, a polypeptide precursor processing carboxypeptidase · PMID 8416959 · 3 records
• Expression, purification, and characterization of two N,N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine · PMID 12119032 · 7 records
• Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases · PMID 15249053 · 21 records
• Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5A · PMID 31985200 · 14 records
• Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis · PMID 16787777 · 12 records
• Extended substrate specificity and first potent irreversible inhibitor/activity-based probe design for Zika virus NS2B-NS3 protease · PMID 28034744 · 5 records
• Extending Cofactor-Tethered Nanomachines to Complex Multienzyme Redox Cascades in Continuous Flow · PMID 42499152 · 37 records
• Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase · PMID 19159229 · 19 records
• Extensive site-directed mutagenesis reveals interconnected functional units in the alkaline phosphatase active site · PMID 25902402 · 34 records
• Extremely stable and versatile carboxylesterase from a hyperthermophilic archaeon · PMID 12147492 · 5 records
• F420H2 oxidase (FprA) from Methanobrevibacter arboriphilus, a coenzyme F420-dependent enzyme involved in O2 detoxification · PMID 15340796 · 4 records
• F420H2:NADP oxidoreductase from Methanobacterium thermoautotrophicum: identification of the encoding gene via functional overexpression in Escherichia coli · PMID 9821972 · 4 records
• FabH selectivity for anteiso branched-chain fatty acid precursors in low-temperature adaptation in Listeria monocytogenes · PMID 19863661 · 7 records
• Fabrication of a 3D nano-bienzyme cascade reactor based on a Dps protein scaffold for chiral amine synthesis · PMID 41793571 · 2 records
• Factor IX mutants with enhanced catalytic activity · PMID 19656280 · 18 records
• Factorizing the role of a critical leucine residue in the binding of substrate to human 20alpha-hydroxysteroid dehydrogenase (AKR1C1): molecular modeling and kinetic studies of the Leu308Val mutant… · PMID 20656485 · 4 records
• Factors affecting the substrate specificity of histone deacetylases · PMID 17428445 · 43 records
• Family-wide analysis of human macrodomains reveals novel activities and identifies PARG as most efficient ADPr-RNA hydrolase · PMID 40102620 · 3 records
• FenF: servicing the Mycosubtilin synthetase assembly line in trans · PMID 17330903 · 14 records
• Ferredoxin-NADP+ reductase from Plasmodium falciparum undergoes NADP+-dependent dimerization and inactivation: functional and crystallographic analysis · PMID 17258767 · 7 records
• Ferredoxin-NADP+ reductase from Pseudomonas putida functions as a ferric reductase · PMID 19114475 · 24 records
• Feruloyl esterases as a tool for the release of phenolic compounds from agro-industrial by-products · PMID 16697997 · 13 records
• Feruloyl esterases from Schizophyllum commune to treat food industry side-streams · PMID 27566510 · 10 records
• Fidelity and Promiscuity of a Mycobacterial Glycosyltransferase · PMID 27302377 · 5 records
• Fidelity, mismatch extension, and proofreading activity of the Plasmodium falciparum apicoplast DNA polymerase · PMID 24147857 · 29 records
• Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum · PMID 22359643 · 30 records
• First characterization of an archaeal amino acid racemase with broad substrate specificity from the hyperthermophile Pyrococcus horikoshii OT-3 · PMID 28343923 · 16 records
• First Crystal Structure of Bacterial Oligopeptidase B in an Intermediate State: The Roles of the Hinge Region Modification and Spermine · PMID 34681120 · 12 records
• First functional and mutational analysis of group 3 N-acetylneuraminate lyases from Lactobacillus antri and Lactobacillus sakei 23K · PMID 24817128 · 13 records
• Flavin-Containing Monooxygenase 3 Polymorphic Variants Significantly Affect Clearance of Tamoxifen and Clomiphene · PMID 29959872 · 12 records
• Fluorescent oligopeptide substrates for kinetic characterization of the specificity of Astacus protease · PMID 2261483 · 25 records
• Fluorinated substrates result in variable leakage of a reaction intermediate during catalysis by dehydroquinate synthase · PMID 21387027 · 9 records
• Fluorogenic Coupled Assays Reveal Catalytic Properties, Inhibition Constants and Cellular Location of Mucin-Active Carbohydrate Sulfatases · PMID 42175861 · 4 records
• Fluorogenic peptide substrates for carboxydipeptidase activity of cathepsin B · PMID 15094828 · 38 records
• Fluorogenic Substrates for In Situ Monitoring of Caspase-3 Activity in Live Cells · PMID 27168077 · 23 records
• Fluorogenic, Subsingle-Turnover Monitoring of Enzymatic Reactions Involving NAD(P)H Provides a Generalized Platform for Directed Ultrahigh-Throughput Evolution of Biocatalysts in Microdroplets · PMID 40127491 · 6 records
• Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28 · PMID 11371182 · 4 records
• Folate synthesis in plants: purification, kinetic properties, and inhibition of aminodeoxychorismate synthase · PMID 16466344 · 5 records
• Folded monomer of HIV-1 protease · PMID 11598128 · 9 records
• Formate Dehydrogenase: The Role of the AMP Cofactor Fragment in Stabilization of the Transition State for Enzyme-Catalyzed Hydride Transfer · PMID 42146174 · 2 records
• Formation of functional cross-species heterodimers of ornithine decarboxylase · PMID 7947774 · 8 records
• Formation of β-glucogallin, the precursor of ellagic acid in strawberry and raspberry · PMID 26884604 · 27 records
• Formiminoglutamase from Trypanosoma cruzi is an arginase-like manganese metalloenzyme · PMID 24261485 · 11 records
• Four amino acids define the CO₂ binding pocket of enoyl-CoA carboxylases/reductases · PMID 31243147 · 20 records
• Four aromatic residues in the active center of cyclodextrin glucanotransferase from alkalophilic Bacillus sp. 1011: effects of replacements on substrate binding and cyclization characteristics · PMID 8061001 · 55 records
• Four deoxynucleoside kinase activities from Drosophila melanogaster are contained within a single monomeric enzyme, a new multifunctional deoxynucleoside kinase · PMID 9461577 · 10 records
• Four Molybdenum-Dependent Steroid C-25 Hydroxylases: Heterologous Overproduction, Role in Steroid Degradation, and Application for 25-Hydroxyvitamin D₃ Synthesis · PMID 29921665 · 8 records
• Four second-sphere residues of Thermus thermophilus SG0.5JP17-16 laccase tune the catalysis by hydrogen-bonding networks · PMID 29516147 · 9 records
• Free energy calculations elucidate substrate binding, gating mechanism, and tolerance-promoting mutations in herbicide target 4-hydroxyphenylpyruvate dioxygenase · PMID 30945368 · 4 records
• From 10,000 to 1: Selective synthesis and enzymatic evaluation of fluorescence resonance energy transfer peptides as specific substrates for chymopapain · PMID 18814838 · 8 records
• From alcohol dehydrogenase to a "one-way" carbonyl reductase by active-site redesign: a mechanistic study of mannitol 2-dehydrogenase from pseudomonas fluorescens · PMID 20639204 · 26 records
• From Identification to Enzymatic Activity Profiling: Comprehensive Characterization of BloCAβ, a Probiotic β-Carbonic Anhydrase From Bifidobacterium longum · PMID 42745684 · 2 records
• FrxA is an S-nitrosoglutathione reductase enzyme that contributes to Helicobacter pylori pathogenicity · PMID 25132107 · 6 records
• Full-length human glutaminase in complex with an allosteric inhibitor · PMID 22049910 · 5 records
• Fumarase From Cyanidioschyzon merolae Stably Shows High Catalytic Activity for Fumarate Hydration Under High Temperature Conditions · PMID 33042040 · 4 records
• Fumarate hydratase isoforms of Leishmania major: subcellular localization, structural and kinetic properties · PMID 22569531 · 8 records
• Fumarate Production by Torulopsis glabrata: Engineering Heterologous Fumarase Expression and Improving Acid Tolerance · PMID 27711153 · 13 records
• Fumarate reductase and succinate oxidase activity of Escherichia coli complex II homologs are perturbed differently by mutation of the flavin binding domain · PMID 16484232 · 12 records
• Function and Structure of MalA/MalA', Iterative Halogenases for Late-Stage C-H Functionalization of Indole Alkaloids · PMID 28777910 · 4 records
• Function of aspartic acid residues in optimum pH control of L-arabinose isomerase from Lactobacillus fermentum · PMID 24220791 · 26 records
• Function of conserved residues of human glutathione synthetase: implications for the ATP-grasp enzymes · PMID 14990577 · 15 records
• Function of phenylalanine 259 and threonine 314 within the substrate binding pocket of the juvenile hormone esterase of Manduca sexta · PMID 20307057 · 5 records
• Functional Analysis of 3-Dehydroquinate Dehydratase/Shikimate Dehydrogenases Involved in Shikimate Pathway in Camellia sinensis · PMID 31681371 · 12 records
• Functional Analysis of Amino Acid Residues Responsible for Substrate Specificity of GH13_17 α‑Glucosidase from Aedes aegypti Saliva (AaMalI) · PMID 41867560 · 25 records
• Functional analysis of conserved cysteines in heparan sulfate N-deacetylase-N-sulfotransferases · PMID 9890952 · 18 records
• Functional analysis of disease-causing mutations in human galactokinase · PMID 12694189 · 14 records
• Functional analysis of disease-causing mutations in human UDP-galactose 4-epimerase · PMID 16302980 · 10 records
• Functional analysis of Gln-237 mutants of HhaI methyltransferase · PMID 7899082 · 12 records
• Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia · PMID 28539365 · 27 records
• Functional analysis of mutant variants of thrombin-activatable fibrinolysis inhibitor resistant to activation by thrombin or plasmin · PMID 19335449 · 17 records
• Functional analysis of propeptide as an intramolecular chaperone for in vivo folding of subtilisin nattokinase · PMID 21074529 · 6 records
• Functional analysis of the nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) enzyme, involved in the late steps of coenzyme B12 biosynthesis in Salmonella enterica · PMID 19880598 · 6 records
• Functional analysis of the purified anandamide-generating phospholipase D as a member of the metallo-beta-lactamase family · PMID 16527816 · 20 records
• Functional analysis of the transmembrane domain and activation cleavage of human corin: design and characterization of a soluble corin · PMID 14559895 · 5 records
• Functional analysis of two solanesyl diphosphate synthases from Arabidopsis thaliana · PMID 15784989 · 8 records
• Functional and mechanistic characterization of the phosphatidyl-myo-inositol mannosyltransferase PimA from Mycobacterium tuberculosis: implications for… · PMID 42688155 · 4 records
• Functional and molecular modelling studies of two hereditary fructose intolerance-causing mutations at arginine 303 in human liver aldolase · PMID 10970798 · 5 records
• Functional and Structural Analysis of a β-Glucosidase Involved in β-1,2-Glucan Metabolism in Listeria innocua · PMID 26886583 · 15 records
• Functional and structural analysis of catalase oxidized by singlet oxygen · PMID 15760714 · 4 records
• Functional and structural changes due to a serine to alanine mutation in the active-site flap of enolase · PMID 12054465 · 5 records
• Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis · PMID 18459799 · 8 records
• Functional and Structural Characterization of Purine Nucleoside Phosphorylase from Kluyveromyces lactis and Its Potential Applications in Reducing Purine Content in Food · PMID 27768715 · 8 records
• Functional and Structural Characterization of the UDP-Glucose Dehydrogenase Involved in Capsular Polysaccharide Biosynthesis from Campylobacter jejuni · PMID 33621065 · 16 records
• Functional annotation and kinetic characterization of PhnO from Salmonella enterica · PMID 16503658 · 19 records
• Functional annotation and structural characterization of a novel lactonase hydrolyzing D-xylono-1,4-lactone-5-phosphate and L-arabino-1,4-lactone-5-phosphate · PMID 24955762 · 19 records
• Functional asymmetry for the active sites of linked 5-aminolevulinate synthase and 8-amino-7-oxononanoate synthase · PMID 21600186 · 8 records
• Functional characterisation of a tropine-forming reductase gene from Brugmansia arborea, a woody plant species producing tropane alkaloids · PMID 26988730 · 6 records
• Functional characterization and categorization of missense mutations that cause methylmalonyl-CoA mutase (MUT) deficiency · PMID 25125334 · 18 records
• Functional characterization and evolution of the isotuberculosinol operon in Mycobacterium tuberculosis and related Mycobacteria · PMID 23091471 · 6 records
• Functional Characterization and Inhibition Analysis of a Glutathione Transferase from Cryptosporidium parvum: A Potential Target for Antiparasitic Drug Development · PMID 42515788 · 3 records
• Functional characterization and mutation analysis of human ATP:Cob(I)alamin adenosyltransferase · PMID 18251506 · 32 records
• Functional Characterization and Structure-Guided Mutational Analysis of the Transsulfuration Enzyme Cystathionine γ-Lyase from Toxoplasma gondii · PMID 30036991 · 11 records
• Functional characterization of a maize UDP-glucosyltransferase involved in the biosynthesis of flavonoid 7-O-glucosides and di-O-glucosides · PMID 39923422 · 9 records
• Functional characterization of a novel class A carbapenemase CAE-1 in carbapenem-resistant Pseudomonas aeruginosa clinical isolates · PMID 41728971 · 14 records
• Functional characterization of a novel p-coumarate 3-hydroxylase from Trametes versicolor · PMID 41615176 · 26 records
• Functional characterization of an aminotransferase required for pyoverdine siderophore biosynthesis in Pseudomonas aeruginosa PAO1 · PMID 15317763 · 4 records
• Functional characterization of an NADPH dependent 2-alkyl-3-ketoalkanoic acid reductase involved in olefin biosynthesis in Stenotrophomonas maltophilia · PMID 21958090 · 7 records
• Functional Characterization of COG1713 (YqeK) as a Novel Diadenosine Tetraphosphate Hydrolase Family · PMID 32152217 · 5 records
• Functional characterization of complement proteases C1s/mannan-binding lectin-associated serine protease-2 (MASP-2) chimeras reveals the higher C4 recognition efficacy of the MASP-2 complement… · PMID 16227207 · 10 records
• Functional characterization of Corynebacterium glutamicum mycothiol S-conjugate amidase · PMID 25514023 · 24 records
• Functional characterization of Delta3,Delta2-enoyl-CoA isomerases from rat liver · PMID 11781327 · 24 records
• Functional characterization of enone oxidoreductases from strawberry and tomato fruit · PMID 17636940 · 6 records
• Functional characterization of four allelic variants of human cytochrome P450 1A2 · PMID 14725854 · 24 records
• Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria · PMID 17531949 · 42 records
• Functional characterization of glutathione S-transferases associated with insecticide resistance in Tetranychus urticae · PMID 26047112 · 6 records
• Functional characterization of leucine-specific domain 1 from eukaryal and archaeal leucyl-tRNA synthetases · PMID 20482517 · 102 records
• Functional characterization of methionine sulfoxide reductases from Leptospira interrogans · PMID 33242654 · 17 records
• Functional characterization of OXA-57, a class D beta-lactamase from Burkholderia pseudomallei · PMID 15793160 · 22 records
• Functional characterization of PLP fold type IV transaminase with a mixed type of activity from Haliangium ochraceum · PMID 30902765 · 2 records
• Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates · PMID 17715131 · 21 records
• Functional characterization of protein variants encoded by nonsynonymous single nucleotide polymorphisms in MARC1 and MARC2 in healthy Caucasians · PMID 24423752 · 21 records
• Functional characterization of residues involved in redox modulation of maize photosynthetic NADP-malic enzyme activity · PMID 22514092 · 16 records
• Functional characterization of single nucleotide polymorphisms with amino acid substitution in CYP1A2, CYP2A6, and CYP2B6 found in the Japanese population · PMID 15681899 · 6 records
• Functional characterization of steroid hydroxylation by cytochrome P450 enzymes from Rhodococcus erythropolis KB1 · PMID 41612368 · 4 records
• Functional characterization of the NS2B/NS3 protease complex from seven viruses belonging to different groups inside the genus Flavivirus · PMID 16504332 · 13 records
• Functional characterization of the promiscuous prenyltransferase responsible for furaquinocin biosynthesis: identification of a physiological polyketide substrate and its prenylated reaction… · PMID 20937800 · 8 records
• Functional Characterization of the SHIP1-Domains Regarding Their Contribution to Inositol 5-Phosphatase Activity · PMID 39858499 · 7 records
• Functional Characterization of the ycjQRS Gene Cluster from Escherichia coli: A Novel Pathway for the Transformation of d-Gulosides to d-Glucosides · PMID 30742415 · 25 records
• Functional characterization of thioesterase superfamily member 1/Acyl-CoA thioesterase 11: implications for metabolic regulation · PMID 22993230 · 22 records
• Functional characterization of two acyltransferases from Populus trichocarpa capable of synthesizing benzyl benzoate and salicyl benzoate, potential intermediates in salicinoid phenolic glycoside… · PMID 25561400 · 12 records
• Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters · PMID 11959859 · 12 records
• Functional cloning and mutational analysis of the human cDNA for phosphoacetylglucosamine mutase: identification of the amino acid residues essential for the catalysis · PMID 11004509 · 16 records
• Functional comparison of citrate synthase isoforms from S. cerevisiae · PMID 17570335 · 3 records
• Functional complementation of an Escherichia coli gap mutant supports an amphibolic role for NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase of Synechocystis sp. strain PCC 6803 · PMID 9226260 · 6 records
• Functional conservation of divergent peptidase_M60 O-glycopeptidases in enterococcus · PMID 42704067 · 6 records
• Functional contribution of coenzyme specificity-determining sites of 7α-hydroxysteroid dehydrogenase from Clostridium absonum · PMID 28826103 · 6 records
• Functional convergence in Z-DNA biosynthesis highlighted by the characterization of nucleotide metabolism enzymes in bacteriophages · PMID 41657244 · 15 records
• Functional definition of the tobacco protoporphyrinogen IX oxidase substrate-binding site · PMID 17134376 · 13 records
• Functional dissection of Escherichia coli phosphotransacetylase structural domains and analysis of key compounds involved in activity regulation · PMID 20236319 · 18 records
• Functional diversification in the Nudix hydrolase gene family drives sesquiterpene biosynthesis in Rosa × wichurana · PMID 32639596 · 10 records
• Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora · PMID 18443127 · 12 records
• Functional diversity inside the Arabidopsis polyamine oxidase gene family · PMID 21081665 · 17 records
• Functional diversity of family 3 β-glucosidases from thermophilic cellulolytic fungus Humicola insolens Y1 · PMID 27271847 · 10 records
• Functional domains and interdomain communication in Candida albicans glucosamine-6-phosphate synthase · PMID 17309446 · 17 records
• Functional effects of active site mutations in NAD+-dependent formate dehydrogenases on transformation of hydrogen carbonate to formate · PMID 30321426 · 13 records
• Functional evaluation of conserved basic residues in human phosphomevalonate kinase · PMID 17902708 · 36 records
• Functional evaluation of serine 252 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase · PMID 18996167 · 12 records
• Functional evolution of C(4) pyruvate, orthophosphate dikinase · PMID 21414960 · 5 records
• Functional expression and characterization of two laccases from the brown rot Fomitopsis pinicola · PMID 34116754 · 12 records
• Functional expression enhancement of Bacillus pumilus CotA-laccase mutant WLF through site-directed mutagenesis · PMID 29224621 · 5 records
• Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants · PMID 10692477 · 11 records
• Functional expression of a plant hydroxynitrile lyase in Escherichia coli by directed evolution: creation and characterization of highly in vivo soluble mutants · PMID 21729945 · 11 records
• Functional expression of aryl-alcohol oxidase in Saccharomyces cerevisiae and Pichia pastoris by directed evolution · PMID 29532900 · 12 records
• Functional expression of human liver cytosolic beta-glucosidase in Pichia pastoris. Insights into its role in the metabolism of dietary glucosides · PMID 11784319 · 17 records
• Functional Expression of Two Unusual Acidic Peroxygenases from Candolleomyces aberdarensis in Yeasts by Adopting Evolved Secretion Mutations · PMID 34288703 · 12 records
• Functional expression, purification, and characterization of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni · PMID 10833462 · 8 records
• Functional identification of key enzymes in calycosin biosynthesis in Astragalus membranaceus and establishment of heterologous expression system · PMID 42005051 · 1 record
• Functional identification of the general acid and base in the dehydration step of indole-3-glycerol phosphate synthase catalysis · PMID 23900843 · 5 records
• Functional identification of the hypoxanthine/guanine transporters YjcD and YgfQ and the adenine transporters PurP and YicO of Escherichia coli K-12 · PMID 24214977 · 23 records
• Functional importance of motif I of pseudouridine synthases: mutagenesis of aligned lysine and proline residues · PMID 10924141 · 7 records
• Functional interaction of diphenols with polyphenol oxidase. Molecular determinants of substrate/inhibitor specificity · PMID 17651437 · 12 records
• Functional linkage of adenine nucleotide binding sites in mammalian muscle 6-phosphofructokinase · PMID 22474333 · 30 records
• Functional reclassification of the putative cinnamyl alcohol dehydrogenase multigene family in Arabidopsis · PMID 14745009 · 30 records
• Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli · PMID 19610625 · 6 records
• Functional role of catalytic triad and oxyanion hole-forming residues on enzyme activity of Escherichia coli thioesterase I/protease I/phospholipase L1 · PMID 16515533 · 16 records
• Functional role of dimerization of human peptidylarginine deiminase 4 (PAD4) · PMID 21731701 · 18 records
• Functional role of fatty acyl-coenzyme A synthetase in the transmembrane movement and activation of exogenous long-chain fatty acids. Amino acid residues within the ATP/AMP signature motif of… · PMID 12034706 · 6 records
• Functional role of glutamine 28 and arginine 39 in double stranded RNA cleavage by human pancreatic ribonuclease · PMID 21408145 · 22 records
• Functional Role of Lanthanides in Enzymatic Activity and Transcriptional Regulation of Pyrroloquinoline Quinone-Dependent Alcohol Dehydrogenases in Pseudomonas putida KT2440 · PMID 28655819 · 6 records
• Functional role of residues involved in substrate binding of human 4-hydroxyphenylpyruvate dioxygenase · PMID 34047349 · 10 records
• Functional role of the linker region in purified human P-glycoprotein · PMID 19490125 · 35 records
• Functional role of Trp-105 of Enterococcus faecalis azoreductase (AzoA) as resolved by structural and mutational analysis · PMID 18757799 · 10 records
• Functional roles of ATP-binding residues in the catalytic site of human mitochondrial NAD(P)+-dependent malic enzyme · PMID 16171388 · 16 records
• Functional roles of the tetramer organization of malic enzyme · PMID 19416979 · 80 records
• Functional roles of Trp337 and Glu632 in Clostridium glucoamylase, as determined by chemical modification, mutagenesis, and the stopped-flow method · PMID 7906268 · 30 records
• Functional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase. Investigations of the putative catalytic glutamate-arginine pair and of residues responsible for… · PMID 17302737 · 13 records
• Functional studies of rat galactokinase · PMID 19433218 · 40 records
• Functional substitution of domain 3 (T1 copper center) of a novel laccase with Cu ions · PMID 30465829 · 10 records
• Functionally important amino acids in Saccharomyces cerevisiae aspartate kinase · PMID 14623312 · 26 records
• Functions of amino acid residues in the active site of Escherichia coli pyrroloquinoline quinone-containing quinoprotein glucose dehydrogenase · PMID 10702303 · 13 records
• Functions of the alpha, beta, and gamma subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase · PMID 19955174 · 26 records
• Functions of the conserved anionic amino acids and those interacting with the substrate phosphate group of phosphoglucose isomerase · PMID 11418102 · 15 records
• Fungal Rutinosidase─Engineering of a Side Tunnel Steers Its Transglycosylation Potential · PMID 42130197 · 6 records
• Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase · PMID 15009205 · 10 records
• Further kinetic characterization of the non-allosteric phosphofructokinase from Escherichia coli K-12 · PMID 6448638 · 32 records
• Further studies of the role of Ser-16 in the regulation of the activity of phenylalanine hydroxylase · PMID 7761394 · 16 records
• Further study on the specificity of D-amino acid oxidase and D-aspartate oxidase and time course for complete oxidation of D-amino acids · PMID 8103425 · 23 records
• Fusion of a family 9 cellulose-binding module improves catalytic potential of Clostridium thermocellum cellodextrin phosphorylase on insoluble cellulose · PMID 21630044 · 15 records
• G521 is the gatekeeper and a key transmembrane domain contact residue of Candida albicans Cdr1 · PMID 41744681 · 11 records
• Gain of D-alanyl-D-lactate or D-lactyl-D-alanine synthetase activities in three active-site mutants of the Escherichia coli D-alanyl-D-alanine ligase B · PMID 8756703 · 50 records
• Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes · PMID 21447318 · 13 records
• Gene cloning and biochemical characterization of a NAD(P)+ -dependent aldehyde dehydrogenase from Bacillus licheniformis · PMID 20495892 · 12 records
• Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production · PMID 23470755 · 7 records
• Gene cloning and enzymatic properties of hyperthermostable beta-glycosidase from Thermus thermophilus HJ6 · PMID 19147104 · 7 records
• Gene cloning and molecular characterization of lysine decarboxylase from Selenomonas ruminantium delineate its evolutionary relationship to ornithine decarboxylases from eukaryotes · PMID 11073919 · 24 records
• Gene cloning, identification, and characterization of the multicopper oxidase CumA from Pseudomonas sp. 593 · PMID 27098101 · 3 records
• Gene cloning, protein characterization, and alteration of product selectivity for the trehalulose hydrolase and trehalulose synthase from "Pseudomonas mesoacidophila" MX-45 · PMID 19783746 · 14 records
• Gene duplications and losses among vertebrate deoxyribonucleoside kinases of the non-TK1 Family · PMID 27906638 · 25 records
• Gene expression and characterization of two 2-oxoacid:ferredoxin oxidoreductases from Aeropyrum pernix K1 · PMID 15848165 · 3 records
• Gene expression patterns and catalytic properties of UDP-D-glucose 4-epimerases from barley (Hordeum vulgare L.) · PMID 16266295 · 4 records
• Gene identification and characterization of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD+-dependent dismutase · PMID 19218190 · 10 records
• General enzymatic screens identify three new nucleotidases in Escherichia coli. Biochemical characterization of SurE, YfbR, and YjjG · PMID 15489502 · 19 records
• Generation of a mutagenized organophosphorus hydrolase for the biodegradation of the organophosphate pesticides malathion and demeton-S · PMID 20132373 · 10 records
• Generation of protein kinase Ck1alpha mutants which discriminate between canonical and non-canonical substrates · PMID 15975091 · 37 records
• Genes malh and pagl of Clostridium acetobutylicum ATCC 824 encode NAD+- and Mn2+-dependent phospho-alpha-glucosidase(s) · PMID 14570887 · 8 records
• Genetic and biochemical characterization of a chromosome-encoded carbapenem-hydrolyzing ambler class D beta-lactamase from Shewanella algae · PMID 15105119 · 12 records
• Genetic and biochemical characterization of FUS-1 (OXA-85), a narrow-spectrum class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum · PMID 16870757 · 7 records
• Genetic and biochemical characterization of GES-5, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae · PMID 17467221 · 8 records
• Genetic and biochemical characterization of OXA-1054, a carbapenem-hydrolyzing class D β-lactamase conferring broad-spectrum β-lactam resistance in Pseudomonas aeruginosa · PMID 42210695 · 6 records
• Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442 · PMID 18212108 · 5 records
• Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes · PMID 20124004 · 15 records
• Genetic and phenotypic characterization of the plasmid-encoded NDM-80 metallo-β-lactamase in Escherichia coli isolated from a pediatric patient · PMID 41847190 · 15 records
• Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States · PMID 21041509 · 16 records
• Genetic replacement of tesB with PTE1 affects chain-length proportions of 3-hydroxyalkanoic acids produced through β-oxidation of oleic acid in Escherichia coli · PMID 20547355 · 14 records
• Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases · PMID 17465518 · 13 records
• Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae · PMID 22403186 · 3 records
• Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family · PMID 16990279 · 60 records
• Genome-wide analysis of the UDP-glucose dehydrogenase gene family in Arabidopsis, a key enzyme for matrix polysaccharides in cell walls · PMID 18057039 · 6 records
• Genome-Wide Identification and Functional Characterization of UDP-Glucosyltransferase Genes Involved in Flavonoid Biosynthesis in Glycine max · PMID 28633497 · 23 records
• Genomics-driven reconstruction of acinetobacter NAD metabolism: insights for antibacterial target selection · PMID 20926389 · 9 records
• Gentisate 1,2-dioxygenase from pseudomonas. Purification, characterization, and comparison of the enzymes from Pseudomonas testosteroni and Pseudomonas acidovorans · PMID 2156846 · 29 records
• Geraniol and geranial dehydrogenases induced in anaerobic monoterpene degradation by Castellaniella defragrans · PMID 22286981 · 12 records
• Geranyl diphosphate:4-hydroxybenzoate geranyltransferase from Lithospermum erythrorhizon. Cloning and characterization of a ket enzyme in shikonin biosynthesis · PMID 11744717 · 4 records
• Gln49 and Ser174 residues play critical roles in determining the catalytic efficiencies of plant glutamine synthetase · PMID 16338958 · 16 records
• Glucoamylase of Caulobacter crescentus CB15: cloning and expression in Escherichia coli and functional identification · PMID 24468405 · 6 records
• Gluconate dehydratase from the promiscuous Entner-Doudoroff pathway in Sulfolobus solfataricus · PMID 15474024 · 2 records
• Glucose (hexose 6-phosphate) dehydrogenase in liver of rainbow trout · PMID 4397856 · 28 records
• Glucose 6-phosphate dehydrogenase from larval Taenia crassiceps (cysticerci): purification and properties · PMID 18297308 · 3 records
• Glucose dehydrogenase from the halophilic Archaeon Haloferax mediterranei: enzyme purification, characterisation and N-terminal sequence · PMID 8925901 · 3 records
• Glucose dehydrogenase from the thermoacidophilic archaebacterium Sulfolobus solfataricus · PMID 3827812 · 10 records
• Glucose dehydrogenase in beef (Bos taurus) and rainbow trout (Oncorhynchus mykiss) liver: a comparative study · PMID 7553351 · 7 records
• Glucose-6-phosphate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima: expression of the g6pd gene and characterization of an extremely thermophilic enzyme · PMID 12435510 · 9 records
• Glucose-6-phosphate dehydrogenase in barley roots: kinetic properties and localisation of the isoforms · PMID 11525521 · 15 records
• Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase: a unique bifunctional enzyme from Plasmodium falciparum · PMID 21443518 · 13 records
• Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis · PMID 16768451 · 10 records
• Glucosylation of the phytoalexin N-feruloyl tyramine modulates the levels of pathogen-responsive metabolites in Nicotiana benthamiana · PMID 31124249 · 30 records
• Glucosylglycerate Phosphorylase, an Enzyme with Novel Specificity Involved in Compatible Solute Metabolism · PMID 28754708 · 9 records
• Glutaconate CoA-transferase from Acidaminococcus fermentans · PMID 6945182 · 16 records
• Glutamate 264 modulates the pH dependence of the NAD(+)-dependent D-lactate dehydrogenase · PMID 1356978 · 24 records
• Glutamate 325 is a general acid-base catalyst in the reaction catalyzed by fructose-2,6-bisphosphatase · PMID 11123954 · 6 records
• Glutamate 636 of the Escherichia coli pyruvate dehydrogenase-E1 participates in active center communication and behaves as an engineered acetolactate synthase with unusual stereoselectivity · PMID 15802265 · 13 records
• Glutamate dehydrogenase (RocG) in Bacillus licheniformis WX-02: Enzymatic properties and specific functions in glutamic acid synthesis for poly-γ-glutamic acid production · PMID 28193334 · 3 records
• Glutamate Dehydrogenase from Thermus thermophilus Is Activated by AMP and Leucine as a Complex with Catalytically Inactive Adenine Phosphoribosyltransferase Homolog · PMID 31036724 · 20 records
• Glutamate racemase dimerization inhibits dynamic conformational flexibility and reduces catalytic rates · PMID 19552402 · 18 records
• Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis · PMID 27480853 · 5 records
• Glutamate residues at positions 162 and 164 influence the beta-lactamase activity of SHV-14 obtained from Klebsiella pneumoniae · PMID 29228168 · 18 records
• Glutamate residues required for substrate binding and cleavage activity in mitochondrial processing peptidase · PMID 9829990 · 12 records
• Glutamate versus glutamine exchange swaps substrate selectivity in tRNA-guanine transglycosylase: insight into the regulation of substrate selectivity by kinetic and crystallographic studies · PMID 17949745 · 8 records
• Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts · PMID 20427272 · 42 records
• Glutamic oxaloacetic transaminase isozymes from rat liver. Purification and physicochemical characterization · PMID 7410335 · 20 records
• Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP · PMID 29899358 · 18 records
• Glutamine Hydrolysis by Imidazole Glycerol Phosphate Synthase Displays Temperature Dependent Allosteric Activation · PMID 29468164 · 10 records
• Glutamine:phenylpyruvate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8 · PMID 14769873 · 21 records
• Glutathione analogues as substrates or inhibitors that discriminate between allozymes of the MDR-involved human glutathione transferase P1-1 · PMID 27037874 · 10 records
• Glutathione, S-substituted glutathiones, and leukotriene C4 as substrates for peptidylglycine alpha-amidating monooxygenase · PMID 12646261 · 14 records
• Glutathionyl-hydroquinone reductases from poplar are plastidial proteins that deglutathionylate both reduced and oxidized glutathionylated quinones · PMID 25455804 · 12 records
• Gly or Ala substitutions for Pro(210)Thr(211)Asn(212) at the β8-β9 turn of subtilisin Carlsberg increase the catalytic rate and decrease thermostability · PMID 22326746 · 7 records
• Glyceraldehyde dehydrogenases from the thermoacidophilic euryarchaeota Picrophilus torridus and Thermoplasma acidophilum, key enzymes of the non-phosphorylative Entner-Doudoroff pathway, constitute… · PMID 16458304 · 8 records
• Glycerol dehydrogenase plays a dual role in glycerol metabolism and 2,3-butanediol formation in Klebsiella pneumoniae · PMID 24429283 · 8 records
• Glycine 176 affects catalytic properties and stability of the Synechococcus sp. strain PCC6301 ribulose-1,5-bisphosphate carboxylase/oxygenase · PMID 15067012 · 8 records
• Glycine decarboxylase is an unusual amino acid decarboxylase involved in tumorigenesis · PMID 24467211 · 11 records
• Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261 · PMID 17573175 · 31 records
• Glycolysis in Entamoeba histolytica. Biochemical characterization of recombinant glycolytic enzymes and flux control analysis · PMID 15794763 · 136 records
• Glycosyltransferase activity can be selectively modulated by chemical modifications of acceptor substrates · PMID 15081009 · 23 records
• Glyphosate resistance by engineering the flavoenzyme glycine oxidase · PMID 19864430 · 17 records
• GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans · PMID 28062578 · 3 records
• gp180, a protein that binds duck hepatitis B virus particles, has metallocarboxypeptidase D-like enzymatic activity · PMID 9525948 · 6 records
• Graminicide insensitivity correlates with herbicide-binding co-operativity on acetyl-CoA carboxylase isoforms · PMID 12859251 · 30 records
• Groups on the side chain of T252 in Escherichia coli leucyl-tRNA synthetase are important for discrimination of amino acids and cell viability · PMID 15110746 · 9 records
• Gut Bacterial 20-Hydroxysteroid Dehydrogenases Modify Endogenous Glucocorticoids and Corticosteroid Drugs · PMID 42338389 · 15 records
• Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson's disease · PMID 30659181 · 7 records
• H₂-dependent reduction of rubredoxin by FrhAGB hydrogenase in Thermococcus onnurineus NA1 · PMID 42115472 · 2 records
• H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia · PMID 19261609 · 7 records
• H₂S oxidation by nanodisc-embedded human sulfide quinone oxidoreductase · PMID 28512131 · 8 records
• Harnessing the potential of chloroplast-derived expression elements for enhanced production of cellulases in Escherichia coli · PMID 39902317 · 2 records
• HDHD1, which is often deleted in X-linked ichthyosis, encodes a pseudouridine-5'-phosphatase · PMID 20722631 · 8 records
• Heat effect on the structure and activity of the recombinant glutamate dehydrogenase from a hyperthermophilic archaeon Pyrococcus horikoshii · PMID 12590923 · 6 records
• Helicobacter pylori 3-deoxy-D-manno-octulosonate-8-phosphate (KDO-8-P) synthase is a zinc-metalloenzyme · PMID 11904225 · 6 records
• Heme-dependent Inactivation of 5-Aminolevulinate Synthase from Caulobacter crescentus · PMID 30242198 · 8 records
• Heparin antagonists are potent inhibitors of mast cell tryptase · PMID 11401583 · 17 records
• Heparinase I from Flavobacterium heparinum. Role of positive charge in enzymatic activity · PMID 9417072 · 12 records
• Herbivore-induced SABATH methyltransferases of maize that methylate anthranilic acid using s-adenosyl-L-methionine · PMID 20519632 · 6 records
• Heterogeneity and regulation of manganese peroxidases from Phanerochaete chrysosporium · PMID 1592808 · 15 records
• Heterogeneity of glyceraldehyde-3-phosphate dehydrogenase from human brain · PMID 3370218 · 2 records
• Heterologous expression and biochemical characterization of novel pyranose 2-oxidases from the ascomycetes Aspergillus nidulans and Aspergillus oryzae · PMID 21968652 · 19 records
• Heterologous expression and characterization of functional mushroom tyrosinase (AbPPO4) · PMID 28500345 · 6 records
• Heterologous expression and characterization of recombinant Lactococcus lactis neutral endopeptidase (neprilysin) · PMID 8806762 · 19 records
• Heterologous expression and characterization of xylose-tolerant GH 43 family β-xylosidase/α-L-arabinofuranosidase from Limosilactobacillus fermentum and its application in xylan… · PMID 40129454 · 5 records
• Heterologous expression and purification of kynurenine-3-monooxygenase from Pseudomonas fluorescens strain 17400 · PMID 16973376 · 6 records
• Heterologous expression of a Streptomyces cyaneus laccase for biomass modification applications · PMID 28439850 · 3 records
• Heterologous expression of an Agaricus meleagris pyranose dehydrogenase-encoding gene in Aspergillus spp. and characterization of the recombinant enzyme · PMID 19888575 · 8 records
• Heterologous expression of an endogenous rat cytochrome b(5)/cytochrome b(5) reductase fusion protein: identification of histidines 62 and 85 as the heme axial ligands · PMID 11913972 · 16 records
• Heterologous expression of Phanerochaete chrysosporium cellobiose dehydrogenase in Trichoderma reesei · PMID 33407462 · 5 records
• Heterologous Overexpression and Biochemical Characterization of a Nitroreductase from Gluconobacter oxydans 621H · PMID 27138989 · 9 records
• Heterologous overexpression of Glomerella cingulata FAD-dependent glucose dehydrogenase in Escherichia coli and Pichia pastoris · PMID 22151971 · 4 records
• Hibernation impact on the catalytic activities of the mitochondrial D-3-hydroxybutyrate dehydrogenase in liver and brain tissues of jerboa (Jaculus orientalis) · PMID 12964952 · 24 records
• Hidden Activities of Tyrosine Phenol-Lyase and Tryptophan Indole-Lyase: Recombinant PLP-Dependent C-C Lyases as New Biocatalysts for Antimicrobial Thiosulfinate Generation · PMID 41754831 · 11 records
• High affinity, stability, and lactonase activity of serum paraoxonase PON1 anchored on HDL with ApoA-I · PMID 16128586 · 15 records
• High substrate specificity and induction characteristics of trimethylamine-N-oxide reductase of Escherichia coli · PMID 8639717 · 13 records
• High tolerance to simultaneous active-site mutations in TEM-1 beta-lactamase: Distinct mutational paths provide more generalized beta-lactam recognition · PMID 19177359 · 27 records
• High-level expression and characterization of Zea mays cytokinin oxidase/dehydrogenase in Yarrowia lipolytica · PMID 15927342 · 8 records
• High-level expression and purification of rat monoamine oxidase A (MAO A) in Pichia pastoris: comparison with human MAO A · PMID 19883764 · 1 record
• High-level expression of full-length human CYP2E1 in Escherichia coli: Comparison of full-length human CYP2E1 to truncated counterpart shows enhanced association with redox partners · PMID 42398471 · 8 records
• High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon · PMID 17256879 · 6 records
• High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation · PMID 32111831 · 9 records
• High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase · PMID 15795226 · 6 records
• High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase · PMID 22496096 · 4 records
• High-Throughput Screening of Coenzyme Preference Change of Thermophilic 6-Phosphogluconate Dehydrogenase from NADP(+) to NAD(.) · PMID 27587230 · 14 records
• High-yield expression, purification, and characterization of active, soluble Bacteroides fragilis metallo-beta-lactamase, CcrA · PMID 9126607 · 12 records
• High-yield production of aromatic peroxygenase by the agaric fungus Marasmius rotula · PMID 21988939 · 6 records
• Highly conserved salt bridge stabilizes a proteinase K subfamily enzyme, Aqualysin I, from Thermus aquaticus YT-1 · PMID 25136511 · 10 records
• Highly efficient chitinase production from Chitinibacter mangrovi FCG-7T and immunomodulatory efficacy of generated GlcNAc in cyclophosphamide-induced… · PMID 42199541 · 1 record
• Highly stable L-lysine 6-dehydrogenase from the thermophile Geobacillus stearothermophilus isolated from a Japanese hot spring: characterization, gene cloning and sequencing, and expression · PMID 14766574 · 6 records
• Highly stereoselective biosynthesis of (R)-α-hydroxy carboxylic acids through rationally re-designed mutation of D-lactate dehydrogenase · PMID 24292439 · 4 records
• Hirschioporus abietinus Laccase: Cloning, Heterologous Expression, Characterization and Solvent Tolerance Evaluation · PMID 41683436 · 9 records
• His-357 of beta-galactosidase (Escherichia coli) interacts with the C3 hydroxyl in the transition state and helps to mediate catalysis · PMID 9665715 · 27 records
• His-391 of beta-galactosidase (Escherichia coli) promotes catalyses by strong interactions with the transition state · PMID 11310566 · 15 records
• His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis · PMID 9890879 · 11 records
• Histidine 295 and histidine 510 are crucial for the enzymatic degradation of heparan sulfate by heparinase III · PMID 10747789 · 12 records
• Histidine 296 is essential for the catalysis in Lactobacillus plantarum D-lactate dehydrogenase · PMID 8349682 · 7 records
• Histidine 454 plays an important role in polymerization of human glutamate dehydrogenase · PMID 12681501 · 16 records
• Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding · PMID 18783250 · 34 records
• Histidine 61: an important heme ligand in the soluble fumarate reductase from Shewanella frigidimarina · PMID 14609326 · 10 records
• Histidine Ethylation by Histidine Methyltransferases SETD3 and METTL9 · PMID 42307994 · 3 records
• Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin · PMID 35481649 · 6 records
• Histone deacetylase 10 structure and molecular function as a polyamine deacetylase · PMID 28516954 · 78 records
• Hofmeister effects on activity and stability of alkaline phosphatase · PMID 20025997 · 12 records
• Homologs of the Rml enzymes from Salmonella enterica are responsible for dTDP-beta-L-rhamnose biosynthesis in the gram-positive thermophile Aneurinibacillus thermoaerophilus DSM 10155 · PMID 12147463 · 8 records
• Homology modeling and prediction of the amino acid residues participating in the transfer of acetyl-CoA to arylalkylamine by the N-acetyltransferase from Chryseobacterium sp · PMID 28721586 · 20 records
• Horse liver alcohol dehydrogenase SS: purification and characterization of the homogenous isoenzyme · PMID 20851 · 24 records
• Horse liver aldehyde dehydrogenase. Purification and characterization of two isozymes · PMID 1244351 · 16 records
• Hot or not? Discovery and characterization of a thermostable alditol oxidase from Acidothermus cellulolyticus 11B · PMID 22231860 · 7 records
• How does Pseudomonas fluorescens avoid suicide from its antibiotic pseudomonic acid?: Evidence for two evolutionarily distinct isoleucyl-tRNA synthetases conferring self-defense · PMID 12672810 · 9 records
• How pantothenol intervenes in Coenzyme-A biosynthesis of Mycobacterium tuberculosis · PMID 17679145 · 6 records
• How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state · PMID 25619277 · 2 records
• Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains · PMID 15065880 · 28 records
• Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity · PMID 24434280 · 4 records
• Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and… · PMID 10998348 · 26 records
• Human aldehyde dehydrogenase. Activity with aldehyde metabolites of monoamines, diamines, and polyamines · PMID 2071588 · 22 records
• Human aldehyde dehydrogenase: metabolism of putrescine and histamine · PMID 3324802 · 12 records
• Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function · PMID 14766013 · 3 records
• Human aldolase C: characterization of the recombinant enzyme expressed in Escherichia coli · PMID 7982900 · 10 records
• Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release · PMID 32499479 · 17 records
• Human and Plasmodium serine hydroxymethyltransferases differ in rate-limiting steps and pH-dependent substrate inhibition behavior · PMID 28760597 · 21 records
• Human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase is a single-domain multifunctional enzyme. Characterization of a novel 17beta-hydroxysteroid dehydrogenase · PMID 10329704 · 6 records
• Human carbonyl reductase 1 as efficient catalyst for the reduction of glutathionylated aldehydes derived from lipid peroxidation · PMID 27562619 · 7 records
• Human carbonyl reductase 1 is an S-nitrosoglutathione reductase · PMID 18826943 · 1 record
• Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase · PMID 19000905 · 10 records
• Human carbonyl reductase catalyzes reduction of 4-oxonon-2-enal · PMID 15476404 · 3 records
• Human carboxymethylenebutenolidase as a bioactivating hydrolase of olmesartan medoxomil in liver and intestine · PMID 20177059 · 6 records
• Human carboxypeptidase M. Purification and characterization of a membrane-bound carboxypeptidase that cleaves peptide hormones · PMID 2914904 · 4 records
• Human CTP:phosphoethanolamine cytidylyltransferase: enzymatic properties and unequal catalytic roles of CTP-binding motifs in two cytidylyltransferase domains · PMID 24802409 · 8 records
• Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE · PMID 25855791 · 6 records
• Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone… · PMID 14672942 · 7 records
• Human cytosolic adenylate kinase allelozymes; purification and characterization · PMID 1969292 · 9 records
• Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties · PMID 30500180 · 45 records
• Human cytosolic folylpoly-gamma-glutamate synthase · PMID 9250977 · 24 records
• Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism · PMID 19218247 · 12 records
• Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation · PMID 26075750 · 7 records
• Human dehydrogenase/reductase (SDR family) member 11 is a novel type of 17β-hydroxysteroid dehydrogenase · PMID 26920053 · 46 records
• Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: a kinetic and thermodynamic study · PMID 12809503 · 8 records
• Human endonuclease III acts preferentially on DNA damage opposite guanine residues in DNA · PMID 11380260 · 12 records
• Human enteropeptidase light chain: bioengineering of recombinants and kinetic investigations of structure and function · PMID 23436726 · 9 records
• Human flavin-containing monooxygenase 2.1 catalyzes oxygenation of the antitubercular drugs thiacetazone and ethionamide · PMID 18948378 · 7 records
• Human glutathione transferases catalyze the reaction between glutathione and nitrooleic acid · PMID 40024478 · 6 records
• Human hereditary glutathione synthetase deficiency: kinetic properties of mutant enzymes · PMID 15056072 · 16 records
• Human histone demethylase LSD1 reads the histone code · PMID 16223729 · 6 records
• Human IDO2 exhibits unique binding affinities distinct to those of human IDO1 · PMID 41804238 · 8 records
• Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1 · PMID 24875753 · 12 records
• Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines · PMID 11557028 · 12 records
• Human liver akdehyde dehydrogenase. Kinetics of aldehyde oxidation · PMID 170276 · 2 records
• Human liver aldehyde dehydrogenases: new method of purification of the major mitochondrial and cytosolic enzymes and re-evaluation of their kinetic properties · PMID 8155713 · 8 records
• Human liver fatty aldehyde dehydrogenase: microsomal localization, purification, and biochemical characterization · PMID 9133646 · 22 records
• Human malaria parasite orotate phosphoribosyltransferase: functional expression, characterization of kinetic reaction mechanism and inhibition profile · PMID 15003844 · 13 records
• Human metastasis regulator protein H-prune is a short-chain exopolyphosphatase · PMID 18700747 · 16 records
• Human microsomal prostaglandin E synthase-1: purification, functional characterization, and projection structure determination · PMID 12672824 · 3 records
• Human missense variants in F3 impair the initiation of blood coagulation · PMID 41100734 · 20 records
• Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis · PMID 17050531 · 36 records
• Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase · PMID 14676218 · 17 records
• Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase · PMID 29225823 · 4 records
• Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP · PMID 11139615 · 3 records
• Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity · PMID 19744929 · 14 records
• Human neuronal nitric oxide synthase can catalyze one-electron reduction of adriamycin: role of flavin domain · PMID 15196992 · 15 records
• Human NRDRB1, an alternatively spliced isoform of NADP(H)-dependent retinol dehydrogenase/reductase enhanced enzymatic activity of benzil · PMID 23128527 · 14 records
• Human pancreas protein 2 (PAN2) has a retinal reductase activity and is ubiquitously expressed in human tissues · PMID 12435598 · 6 records
• Human peroxisomal multifunctional enzyme type 2. Site-directed mutagenesis studies show the importance of two protic residues for 2-enoyl-CoA hydratase 2 activity · PMID 10671535 · 4 records
• Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate · PMID 25406093 · 6 records
• Human placental cytoplasmic 5'-nucleotidase. Kinetic properties and inhibition · PMID 3001058 · 12 records
• Human placental estradiol-17 beta dehydrogenase. II. Kinetics and substrate specificities · PMID 14413943 · 14 records
• Human pyridoxal phosphatase. Molecular cloning, functional expression, and tissue distribution · PMID 14522954 · 3 records
• Human retinol dehydrogenase 13 (RDH13) is a mitochondrial short-chain dehydrogenase/reductase with a retinaldehyde reductase activity · PMID 18039331 · 5 records
• Human serine racemase is nitrosylated at multiple sites · PMID 29410194 · 3 records
• Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes · PMID 10947957 · 8 records
• Human sulfide:quinone oxidoreductase catalyzes the first step in hydrogen sulfide metabolism and produces a sulfane sulfur metabolite · PMID 22852582 · 7 records
• Human symbiont Bacteroides thetaiotaomicron synthesizes 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid (KDN) · PMID 18804026 · 11 records
• Human testis specific protein: a new member of aldo-keto reductase superfamily · PMID 12604216 · 5 records
• Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation · PMID 23152787 · 3 records
• Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid · PMID 15039294 · 11 records
• Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications · PMID 17696873 · 7 records
• Huntington's disease LIG1 modifier variant increases ligase fidelity and suppresses somatic CAG repeat expansion · PMID 41770933 · 6 records
• Hydration and hydrolysis define antibiotic resistance conferred by macrolide esterases · PMID 42455676 · 9 records
• Hydrogen bond residue positioning in the 599-611 loop of thimet oligopeptidase is required for substrate selection · PMID 18959747 · 34 records
• Hydrogen Peroxide-Based Fluorometric Assay for Real-Time Monitoring of SAM-Dependent Methyltransferases · PMID 30406092 · 1 record
• Hydrogen Peroxide-Resistant CotA and YjqC of Bacillus altitudinis Spores Are a Promising Biocatalyst for Catalyzing Reduction of Sinapic Acid and Sinapine in Rapeseed Meal · PMID 27362423 · 12 records
• Hydrolase and transferase activities of the beta-1,3-exoglucanase of Candida albicans · PMID 10469155 · 14 records
• Hydrolysis and transglycosylation activity of a thermostable recombinant beta-glycosidase from Sulfolobus acidocaldarius · PMID 19626290 · 8 records
• Hydrolysis by plasma kallikrein of fluorogenic peptides derived from prorenin processing site · PMID 11004531 · 32 records
• Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase · PMID 11815627 · 9 records
• Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and… · PMID 15100172 · 7 records
• Hydrolysis of N-succinyl-L,L-diaminopimelic acid by the Haemophilus influenzae dapE-encoded desuccinylase: metal activation, solvent isotope effects, and kinetic mechanism · PMID 9671518 · 4 records
• Hydrolysis of Nonpolar n-Alkyl Ferulates by Feruloyl Esterases · PMID 27600375 · 24 records
• Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase · PMID 17649977 · 9 records
• Hydrolysis of thionopeptides by the aminopeptidase from Aeromonas proteolytica: insight into substrate binding · PMID 11888288 · 18 records
• Hydrolytic metabolism of pyrethroids by human and other mammalian carboxylesterases · PMID 16387282 · 14 records
• Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase · PMID 11555657 · 32 records
• Hydrophobic anion activation of human liver chi chi alcohol dehydrogenase · PMID 2043614 · 38 records
• Hydrophobic interactions of a substrate with L193 on the flexible substrate-binding loop contribute to 3α-hydroxysteroid dehydrogenase/carbonyl reductase catalytic efficiency · PMID 41940686 · 63 records
• Hydrophobic Mutagenesis and Semi-rational Engineering of Arginine Deiminase for Markedly Enhanced Stability and Catalytic Efficiency · PMID 26041055 · 5 records
• Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations · PMID 31324778 · 7 records
• Hydrophobic repacking of the dimer interface of triosephosphate isomerase by in silico design and directed evolution · PMID 18439027 · 4 records
• Hydroxamate formation in the lipopeptide containing siderophore taiwachelin · PMID 42291503 · 10 records
• Hydroxyatrazine N-ethylaminohydrolase (AtzB): an amidohydrolase superfamily enzyme catalyzing deamination and dechlorination · PMID 17660279 · 5 records
• Hydroxycinnamoyl-coenzyme A: tetrahydroxyhexanedioate hydroxycinnamoyl transferase (HHHT) from Phaseolus vulgaris L.: phylogeny, expression pattern, kinetic parameters, and active… · PMID 39989742 · 12 records
• Hydroxylation of p-substituted phenols by tyrosinase: further insight into the mechanism of tyrosinase activity · PMID 22732412 · 10 records
• Hyperactivation of human acidic chitinase (Chia) for potential medical use · PMID 39706263 · 5 records
• Hyperthermophilic asparaginase mutants with enhanced substrate affinity and antineoplastic activity: structural insights on their mechanism of action · PMID 22166247 · 8 records
• Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core · PMID 30457329 · 9 records
• Hysteresis and negative cooperativity in human UDP-glucose dehydrogenase · PMID 23363239 · 4 records
• ICEKAT: an interactive online tool for calculating initial rates from continuous enzyme kinetic traces · PMID 32410570 · 7 records
• Identification and biochemical characterization of a thermostable malate dehydrogenase from the mesophile Streptomyces coelicolor A3(2) · PMID 21071865 · 4 records
• Identification and biochemical characterization of polyamine oxidases in amphioxus: Implications for emergence of vertebrate-specific spermine and acetylpolyamine oxidases · PMID 26367330 · 24 records
• Identification and biochemical characterization of the fructokinase gene family in Arabidopsis thaliana · PMID 28441933 · 14 records
• Identification and characterisation of a novel acylpeptide hydrolase from Sulfolobus solfataricus: structural and functional insights · PMID 22655081 · 8 records
• Identification and characterisation of Arabidopsis glycosyltransferases capable of glucosylating coniferyl aldehyde and sinapyl aldehyde · PMID 15907484 · 6 records
• Identification and characterisation of human aldose 1-epimerase · PMID 12753898 · 7 records
• Identification and characteristics of a novel acquired aminoglycoside phosphotransferase, APH(3')-IVb, from Riemerella anatipestifer · PMID 41874382 · 3 records
• Identification and characteristics of a novel fosfomycin glutathione transferase, FosA12, from an MDR clinical isolate of Proteus vulgaris · PMID 41984079 · 2 records
• Identification and characterization of (1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase in the menaquinone biosynthesis of Escherichia coli · PMID 18284213 · 5 records
• Identification and characterization of a bacterial glycerol-1-phosphate dehydrogenase: Ni(2+)-dependent AraM from Bacillus subtilis · PMID 18558723 · 5 records
• Identification and characterization of a bile salt hydrolase from Lactobacillus salivarius for development of novel alternatives to antibiotic growth promoters · PMID 23064348 · 6 records
• Identification and characterization of a core fucosidase from the bacterium Elizabethkingia meningoseptica · PMID 29196602 · 24 records
• Identification and characterization of a mycobacterial NAD⁺-dependent alcohol dehydrogenase with superior reduction of diacetyl to (S)-acetoin · PMID 25082080 · 7 records
• Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacterium Bifidobacterium kashiwanohense · PMID 31123167 · 6 records
• Identification and characterization of a novel anthocyanin malonyltransferase from scarlet sage (Salvia splendens) flowers: an enzyme that is phylogenetically separated from other anthocyanin… · PMID 15165190 · 4 records
• Identification and characterization of a novel carboxylesterase (FpbH) that hydrolyzes aryloxyphenoxypropionate herbicides · PMID 28058522 · 6 records
• Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance · PMID 8328987 · 21 records
• Identification and characterization of a novel human aldose reductase-like gene · PMID 9565553 · 19 records
• Identification and characterization of a novel nitrilase from Pseudomonas fluorescens Pf-5 · PMID 19153727 · 11 records
• Identification and characterization of a plastid-localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde… · PMID 18495639 · 5 records
• Identification and characterization of a strict and a promiscuous N-acetylglucosamine-1-P uridylyltransferase in Arabidopsis · PMID 20557289 · 9 records
• Identification and characterization of a tyramine-glutamate ligase (MfnD) involved in methanofuran biosynthesis · PMID 25211225 · 11 records
• Identification and characterization of an archaeal ketopantoate reductase and its involvement in regulation of coenzyme A biosynthesis · PMID 23941541 · 13 records
• Identification and characterization of bacterial cysteine dioxygenases: a new route of cysteine degradation for eubacteria · PMID 16855246 · 5 records
• Identification and characterization of BAHD hydroxycinnamoyltransferases in the fern Neoblechnum brasiliense · PMID 41904984 · 24 records
• Identification and characterization of bifunctional proline racemase/hydroxyproline epimerase from archaea: discrimination of substrates and molecular evolution · PMID 25786142 · 30 records
• Identification and characterization of CYP79D16 and CYP71AN24 catalyzing the first and second steps in L-phenylalanine-derived cyanogenic glycoside biosynthesis in the Japanese apricot, Prunus mume… · PMID 25015725 · 6 records
• Identification and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis · PMID 20491913 · 28 records
• Identification and characterization of MalA in the maltose/maltodextrin operon of Sulfolobus acidocaldarius DSM639 · PMID 23396915 · 6 records
• Identification and characterization of multiple curcumin synthases from the herb Curcuma longa · PMID 19622354 · 4 records
• Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea · PMID 32193380 · 12 records
• Identification and characterization of novel broad-spectrum amino acid racemases from Escherichia coli and Bacillus subtilis · PMID 28894939 · 4 records
• Identification and characterization of prostaglandin F_2α 9-dehydrogenase from Rhodotorula kratochvilovae · PMID 41940877 · 2 records
• Identification and characterization of R75estA, a halophilic polyester-degrading enzyme from a marine bacterium · PMID 42499663 · 3 records
• Identification and characterization of RacX, a new broad-specificity amino acid racemase from a novel taxon within the order Flavobacteriales · PMID 41427669 · 23 records
• Identification and characterization of single-domain thiosulfate sulfurtransferases from Arabidopsis thaliana · PMID 12482606 · 6 records
• Identification and characterization of the BAHD acyltransferase malonyl CoA: anthocyanidin 5-O-glucoside-6''-O-malonyltransferase (At5MAT) in Arabidopsis thaliana · PMID 17292360 · 6 records
• Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase · PMID 34019876 · 12 records
• Identification and characterization of the Tuber borchii D-mannitol dehydrogenase which defines a new subfamily within the polyol-specific medium chain dehydrogenases · PMID 17317242 · 4 records
• Identification and characterization of trans-3-hydroxy-l-proline dehydratase and Δ(1)-pyrroline-2-carboxylate reductase involved in trans-3-hydroxy-l-proline metabolism of bacteria · PMID 24649405 · 23 records
• Identification and characterization of two arylalkylamine N-acetyltransferases in the yellow fever mosquito, Aedes aegypti · PMID 21645618 · 14 records
• Identification and characterization of two new 5-keto-4-deoxy-D-Glucarate Dehydratases/Decarboxylases · PMID 27855668 · 3 records
• Identification and clarification of the role of key active site residues in bacterial glutathione S-transferase zeta/maleylpyruvate isomerase · PMID 21672526 · 18 records
• Identification and designing of the S3 site of aqualysin I, a thermophilic subtilisin-related serine protease · PMID 10348901 · 18 records
• Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants · PMID 17050781 · 14 records
• Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity · PMID 10391916 · 17 records
• Identification and Functional Characterization of Anthocyanidin 3-O-Glucosyltransferases OsA3GT1 and OsA3GT2 in Black Rice · PMID 42043698 · 3 records
• Identification and functional characterization of arylamine N-acetyltransferases in eubacteria: evidence for highly selective acetylation of 5-aminosalicylic acid · PMID 11344150 · 42 records
• Identification and functional characterization of sorbitol-6-phosphate dehydrogenase protein from rice and structural elucidation by in silico approach · PMID 24817585 · 2 records
• Identification and molecular characterization of a novel flavin-free NADPH preferred azoreductase encoded by azoB in Pigmentiphaga kullae K24 · PMID 20233432 · 4 records
• Identification and molecular characterization of the first alpha -xylosidase from an archaeon · PMID 10801892 · 6 records
• Identification and properties of the prosthetic group of choline oxidase from Alcaligenes sp · PMID 6997283 · 2 records
• Identification and Thermal Stability Modification of a Zearalenone Lactone Hydrolase ZHD30L · PMID 42646752 · 2 records
• Identification by mutagenesis of arginines in the substrate binding site of the porcine NADP-dependent isocitrate dehydrogenase · PMID 10681542 · 10 records
• Identification in the mould Hypocrea jecorina of a gene encoding an NADP(+): d-xylose dehydrogenase · PMID 18031347 · 7 records
• Identification of 4-coumarate:coenzyme A ligase (4CL) substrate recognition domains · PMID 11576429 · 23 records
• Identification of 7 alpha,12 alpha-dihydroxy-5 beta-cholestan-3-one 3 alpha-hydroxysteroid dehydrogenase · PMID 3459552 · 6 records
• Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens · PMID 18722632 · 12 records
• Identification of a 5'-deoxyadenosine deaminase in Methanocaldococcus jannaschii and its possible role in recycling the radical S-adenosylmethionine enzyme reaction product 5'-deoxyadenosine · PMID 24375099 · 15 records
• Identification of a Catalytic Nucleophile-Activating Network in the endo-α-N-Acetylgalactosaminidase of Family GH101 · PMID 34694774 · 19 records
• Identification of a determinant for strict NADP(H)-specificity and high sensitivity to mixed-type steroid inhibitor of rabbit aldo-keto reductase 1C33 by site-directed mutagenesis · PMID 25660042 · 48 records
• Identification of a dTDP-rhamnose biosynthetic pathway that oscillates with the molting cycle in Caenorhabditis elegans · PMID 27009306 · 10 records
• Identification of a flexible loop region (297-313) of urokinase-type plasminogen activator, which helps determine its catalytic activity · PMID 9295329 · 20 records
• Identification of a Highly Specific Isoflavone 7-O-glucosyltransferase in the soybean (Glycine max (L.) Merr.) · PMID 26019269 · 16 records
• Identification of a hotdog fold thioesterase involved in the biosynthesis of menaquinone in Escherichia coli · PMID 23564174 · 7 records
• Identification of a hydrophobic exosite on tissue type plasminogen activator that modulates specificity for plasminogen · PMID 8999865 · 60 records
• Identification of a hypothetical protein from Podospora anserina as a nitroalkane oxidase · PMID 20481475 · 6 records
• Identification of a long-range protein network that modulates active site dynamics in extremophilic alcohol dehydrogenases · PMID 23525111 · 31 records
• Identification of a Novel (-)-5-Epieremophilene Synthase from Salvia miltiorrhiza via Transcriptome Mining · PMID 28487717 · 3 records
• Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia · PMID 25092711 · 18 records
• Identification of a novel aminoglycoside nucleotidyltransferase gene in Morganella morganii from farm sewage · PMID 40119290 · 2 records
• Identification of a Novel Fungal α‑l‑Fucosidase with Transfucosylation Potential · PMID 42626434 · 2 records
• Identification of a novel ligand binding site in phosphoserine phosphatase from the hyperthermophilic archaeon Thermococcus onnurineus · PMID 23239422 · 13 records
• Identification of a novel NADH-specific aldo-keto reductase using sequence and structural homologies · PMID 16813561 · 37 records
• Identification of a novel prostaglandin f(2alpha) synthase in Trypanosoma brucei · PMID 11067881 · 5 records
• Identification of a novel prostaglandin reductase reveals the involvement of prostaglandin E2 catabolism in regulation of peroxisome proliferator-activated receptor gamma activation · PMID 17449869 · 5 records
• Identification of a novel trifunctional homoisocitrate dehydrogenase and modulation of the broad substrate specificity through site-directed mutagenesis · PMID 16139794 · 8 records
• Identification of a novel UDP-sugar pyrophosphorylase with a broad substrate specificity in Trypanosoma cruzi · PMID 20482518 · 12 records
• Identification of a puromycin-sensitive aminopeptidase from zebrafish (Danio rerio) · PMID 21276865 · 9 records
• Identification of a S-(2-succino)cysteine breakdown pathway that uses a novel S-(2-succino) lyase · PMID 36309089 · 10 records
• Identification of a serine hydrolase as a key determinant in the microbial degradation of polychlorinated biphenyls · PMID 10821847 · 9 records
• Identification of a TeO32- reductase/mycothione reductase from Rhodococcus erythropolis PR4 · PMID 33377161 · 6 records
• Identification of acceptor substrate binding subsites +2 and +3 in the amylomaltase from Thermus thermophilus HB8 · PMID 17407266 · 19 records
• Identification of active site residues in mevalonate diphosphate decarboxylase: implications for a family of phosphotransferases · PMID 15169949 · 6 records
• Identification of ADP-ribosylation site in human glutamate dehydrogenase isozymes · PMID 16023112 · 36 records
• Identification of Allosteric Inhibitors against Active Caspase-6 · PMID 30940883 · 10 records
• Identification of amino acid residues contributing to the mechanism of cooperativity in Escherichia coli D-3-phosphoglycerate dehydrogenase · PMID 16363798 · 41 records
• Identification of amino acid residues essential for the yeast N-acetyltransferase Mpr1 activity by site-directed mutagenesis · PMID 18373682 · 24 records
• Identification of amino acid residues involved in substrate recognition of L-xylulose reductase by site-directed mutagenesis · PMID 12604240 · 39 records
• Identification of amino acid residues involved in the activity of phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase. A bifunctional enzyme in the alginate biosynthetic… · PMID 8106458 · 26 records
• Identification of amino acid residues responsible for increased thermostability of feruloyl esterase A from Aspergillus niger using the PoPMuSiC algorithm · PMID 20801026 · 4 records
• Identification of an archaeal 2-hydroxy acid dehydrogenase catalyzing reactions involved in coenzyme biosynthesis in methanoarchaea · PMID 10850983 · 26 records
• Identification of an arginine residue in the dual coenzyme-specific glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides that plays a key role in binding NADP+ but not NAD+ · PMID 8579362 · 28 records
• Identification of an ITPase/XTPase in Escherichia coli by structural and biochemical analysis · PMID 16216582 · 5 records
• Identification of an Unpredicted GAG-PUL in Roseihalotalea indica gen. nov. sp. nov. TK19036T and Characterization of Novel GAG-Lyases with Unique Substrate… · PMID 41892974 · 2 records
• Identification of arginine residues important for the activity of Escherichia coli signal peptidase I · PMID 15195997 · 18 records
• Identification of basic residues involved in substrate binding and catalysis by pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii · PMID 8195200 · 17 records
• Identification of catalysis, substrate, and coenzyme binding sites and improvement catalytic efficiency of formate dehydrogenase from Candida boidinii · PMID 27198726 · 8 records
• Identification of catalytic and substrate-binding site residues in Bacillus cereus ATCC7064 oligo-1,6-glucosidase · PMID 11676021 · 5 records
• Identification of catalytic bases in the active site of Escherichia coli methylglyoxal synthase: cloning, expression, and functional characterization of conserved aspartic acid residues · PMID 9665712 · 21 records
• Identification of catalytic residues in human mevalonate kinase · PMID 9325256 · 12 records
• Identification of catalytic residues of Ca2+-independent 1,2-alpha-D-mannosidase from Aspergillus saitoi by site-directed mutagenesis · PMID 12702721 · 9 records
• Identification of catalytic residues of pepstatin-insensitive carboxyl proteinases from prokaryotes by site-directed mutagenesis · PMID 10488127 · 9 records
• Identification of catalytically essential residues in Escherichia coli esterase by site-directed mutagenesis · PMID 10431819 · 7 records
• Identification of catalytically important amino acid residues for enzymatic reduction of glyoxylate in plants · PMID 24076009 · 16 records
• Identification of catalytically important residues in yeast transketolase · PMID 9398292 · 21 records
• Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition · PMID 12499375 · 16 records
• Identification of critical residues of choline kinase A2 from Caenorhabditis elegans · PMID 14960577 · 50 records
• Identification of critical residues of the mycobacterial dephosphocoenzyme a kinase by site-directed mutagenesis · PMID 21264299 · 17 records
• Identification of crucial amino acid residues involved in large ring cyclodextrin synthesis by amylomaltase from Corynebacterium glutamicum · PMID 36698977 · 15 records
• Identification of crucial amino acids in mouse aldehyde oxidase 3 that determine substrate specificity · PMID 24358164 · 46 records
• Identification of crucial amino acids of bacterial Peptide deformylases affecting enzymatic activity in response to oxidative stress · PMID 24142250 · 4 records
• Identification of cysteine and arginine residues essential for the phosphotransacetylase from Methanosarcina thermophila · PMID 9401029 · 26 records
• Identification of Dephospho-Coenzyme A (Dephospho-CoA) Kinase in Thermococcus kodakarensis and Elucidation of the Entire CoA Biosynthesis Pathway in Archaea · PMID 31337720 · 2 records
• Identification of domains involved in tetramerization and malate inhibition of maize C4-NADP-malic enzyme · PMID 17150960 · 24 records
• Identification of Drosophila and human 7-methyl GMP-specific nucleotidases · PMID 23223233 · 13 records
• Identification of enzymes acting on alpha-glycated amino acids in Bacillus subtilis · PMID 15556630 · 24 records
• Identification of Escherichia coli K12 YdcW protein as a gamma-aminobutyraldehyde dehydrogenase · PMID 16023116 · 4 records
• Identification of essential active-site residues in ornithine decarboxylase of Nicotiana glutinosa decarboxylating both L-ornithine and L-lysine · PMID 11736657 · 9 records
• Identification of essential amino acid residues in valine dehydrogenase from Streptomyces albus · PMID 16554717 · 8 records
• Identification of essential arginines in the acetate kinase from Methanosarcina thermophila · PMID 10736166 · 19 records
• Identification of essential residues in 2',3'-cyclic nucleotide 3'-phosphodiesterase. Chemical modification and site-directed mutagenesis to investigate the role of cysteine and histidine residues… · PMID 11278504 · 16 records
• Identification of Euglena gracilis β-1,3-glucan phosphorylase and establishment of a new glycoside hydrolase (GH) family GH149 · PMID 29317507 · 12 records
• Identification of functional conserved residues of CTP:glycerol-3-phosphate cytidylyltransferase. Role of histidines in the conserved HXGH in catalysis · PMID 9182537 · 62 records
• Identification of functionally important residues of Arabidopsis thaliana S-adenosylmethionine decarboxylase · PMID 10578049 · 7 records
• Identification of fungal oxaloacetate hydrolyase within the isocitrate lyase/PEP mutase enzyme superfamily using a sequence marker-based method · PMID 17654546 · 17 records
• Identification of genus Nitrosovibrio, ammonia-oxidizing bacteria, by comparison of N-terminal amino acid sequences of phosphoglycerate kinase · PMID 16233723 · 22 records
• Identification of glutathione (GSH)-independent glyoxalase III from Schizosaccharomyces pombe · PMID 24758716 · 5 records
• Identification of grass-specific enzyme that acylates monolignols with p-coumarate · PMID 22267741 · 9 records
• Identification of isoaspartyl-containing sequences in peptides and proteins that are usually poor substrates for the class II protein carboxyl methyltransferase · PMID 2303443 · 10 records
• Identification of Key Amino Acid Residues in the Adenylation Domains of Polymyxin Synthetase Responsible for l‑Threonine Adenylation in Paenibacillus polymyxa NBRC3020 · PMID 42757158 · 6 records
• Identification of key amino acids responsible for the substantially higher affinities of human type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD1) for substrates, coenzymes, and… · PMID 15797861 · 17 records
• Identification of key functional residues in the active site of human β1,4-galactosyltransferase 7: a major enzyme in the glycosaminoglycan synthesis pathway · PMID 20843813 · 27 records
• Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metabolite · PMID 42363837 · 26 records
• Identification of key residues for activities of atypical glutathione S-transferase of Ceriporiopsis subvermispora, a selective degrader of lignin in woody biomass, by crystallography and functional… · PMID 30928378 · 6 records
• Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases · PMID 21257746 · 25 records
• Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase · PMID 16737955 · 20 records
• Identification of novel peptide substrates for protein farnesyltransferase reveals two substrate classes with distinct sequence selectivities · PMID 19878682 · 70 records
• Identification of polyketide inhibitors targeting 3-dehydroquinate dehydratase in the shikimate pathway of Enterococcus faecalis · PMID 25072253 · 1 record
• Identification of positive and negative determinants of malonyl-CoA sensitivity and carnitine affinity within the amino termini of rat liver- and muscle-type carnitine palmitoyltransferase I · PMID 10969089 · 18 records
• Identification of PpoA from Aspergillus nidulans as a fusion protein of a fatty acid heme dioxygenase/peroxidase and a cytochrome P450 · PMID 19286665 · 5 records
• Identification of rat and human cytochrome p450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerate · PMID 17576809 · 12 records
• Identification of residues Asn89, Ile90, and Val107 of the factor IXa second epidermal growth factor domain that are essential for the assembly of the factor X-activating complex on activated… · PMID 15328360 · 15 records
• Identification of residues essential for a two-step reaction by malonyl-CoA synthetase from Rhizobium trifolii · PMID 10548546 · 24 records
• Identification of residues important for the activity of aldehyde-deformylating oxygenase through investigation into the structure-activity relationship · PMID 28302170 · 28 records
• Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster · PMID 10966789 · 8 records
• Identification of residues of Escherichia coli phosphofructokinase that contribute to nucleotide binding and specificity · PMID 10194349 · 81 records
• Identification of Significant residues for homoallylic substrate binding of Micrococcus luteus B-P 26 undecaprenyl diphosphate synthase · PMID 11346651 · 30 records
• Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity · PMID 16216875 · 9 records
• Identification of specific residues involved in substrate discrimination in two plant O-methyltransferases · PMID 10415125 · 11 records
• Identification of structural determinants of NAD(P)H selectivity and lysine binding in lysine N(6)-monooxygenase · PMID 27503802 · 14 records
• Identification of substrate-binding and selectivity-related residues of maltooligosyltrehalose synthase from the thermophilic archaeon Sulfolobus solfataricus ATCC 35092 · PMID 24564903 · 11 records
• Identification of the acid/base catalyst of a glycoside hydrolase family 3 (GH3) beta-glucosidase from Aspergillus niger ASKU28 · PMID 23201198 · 40 records
• Identification of the active site acid/base catalyst in a bacterial fumarate reductase: a kinetic and crystallographic study · PMID 10978153 · 14 records
• Identification of the amino acid residues essential for proteolytic activity in an archaeal signal peptide peptidase · PMID 16484219 · 13 records
• Identification of the amino acid residues responsible for cold tolerance in Flaveria brownii pyruvate,orthophosphate dikinase · PMID 9038349 · 24 records
• Identification of the Arabidopsis Calmodulin-Dependent NAD⁺ Kinase That Sustains the Elicitor-Induced Oxidative Burst · PMID 31554701 · 6 records
• Identification of the catalytic residues in family 52 glycoside hydrolase, a beta-xylosidase from Geobacillus stearothermophilus T-6 · PMID 12738774 · 59 records
• Identification of the catalytically important histidine of 3-hydroxy-3-methylglutaryl-coenzyme A reductase · PMID 1634543 · 18 records
• Identification of the cellobiose 2-epimerase gene in the genome of Bacteroides fragilis NCTC 9343 · PMID 19202279 · 2 records
• Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A · PMID 17718512 · 8 records
• Identification of the essential catalytic residues and selectivity-related residues of maltooligosyltrehalose trehalohydrolase from the thermophilic archaeon Sulfolobus solfataricus ATCC 35092 · PMID 18563901 · 34 records
• Identification of the gene encoding NADH-rubredoxin oxidoreductase in Clostridium acetobutylicum · PMID 11444870 · 7 records
• Identification of the glucosamine kinase in the chitinolytic pathway of Thermococcus kodakarensis · PMID 29146530 · 5 records
• Identification of the GTP binding site of human glutamate dehydrogenase by cassette mutagenesis and photoaffinity labeling · PMID 11600502 · 22 records
• Identification of the histidine ligands to the binuclear metal center of phosphotriesterase by site-directed mutagenesis · PMID 8155644 · 32 records
• Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells · PMID 25301951 · 9 records
• Identification of the missing links in prokaryotic pentose oxidation pathways: evidence for enzyme recruitment · PMID 16849334 · 10 records
• Identification of the peroxisomal beta-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids · PMID 15060085 · 4 records
• Identification of the rate-limiting step of the peroxygenase reactions catalyzed by the thermophilic cytochrome P450 from Sulfolobus tokodaii strain 7 · PMID 24410761 · 6 records
• Identification of the reactive cysteine residue (Cys227) in human carbonyl reductase · PMID 10091578 · 26 records
• Identification of the reactive cysteine residues in yeast dipeptidyl peptidase III · PMID 19825391 · 5 records
• Identification of the sequence encoding N-acetylneuraminate-9-phosphate phosphatase · PMID 16237198 · 22 records
• Identification of the site of oxidase substrate binding in Scytalidium thermophilum catalase · PMID 30289408 · 10 records
• Identification of the substrate specificity-conferring amino acid residues of 4-coumarate:coenzyme A ligase allows the rational design of mutant enzymes with new catalytic properties · PMID 11323416 · 22 records
• Identification of thermostable glyoxalase I in the fission yeast Schizosaccharomyces pombe · PMID 15042280 · 4 records
• Identification of three key active site residues in the C-terminal domain of human recombinant folylpoly-gamma-glutamate synthetase by site-directed mutagenesis · PMID 10480915 · 24 records
• Identification of two additional members of the membrane-bound dipeptidase family · PMID 12738806 · 4 records
• Identification of Two Distinct Stereoselective Lysine 5-Hydroxylases by Genome Mining Based on Alazopeptin Biosynthetic Enzymes · PMID 39960436 · 9 records
• Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules · PMID 18267101 · 6 records
• Identification of two highly promiscuous thermostable sugar nucleotidylyltransferases for glycorandomization · PMID 29806742 · 21 records
• Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis · PMID 20133360 · 8 records
• Identification of UDP glucosyltransferases from the aluminum-resistant tree Eucalyptus camaldulensis forming β-glucogallin, the precursor of hydrolyzable tannins · PMID 29775866 · 6 records
• Identification of UDP-glucuronosyltransferase (UGT) isoforms involved in the metabolism of Chlorophenols (CPs) · PMID 38705405 · 83 records
• Identification of UDP-glycosyltransferases involved in the biosynthesis of astringent taste compounds in tea (Camellia sinensis) · PMID 26941235 · 8 records
• Identification of UshA as a major enzyme for NAD degradation in Escherichia coli · PMID 24731828 · 4 records
• Identification, characterization, and crystal structure of an aldo-keto reductase (AKR2E4) from the silkworm Bombyx mori · PMID 24012638 · 5 records
• Identification, characterization, and site-directed mutagenesis of recombinant pentachlorophenol 4-monooxygenase · PMID 15262224 · 6 records
• Identification, cloning, heterologous expression, and characterization of a NADPH-dependent 7β-hydroxysteroid dehydrogenase from Collinsella aerofaciens · PMID 21181147 · 5 records
• Identification, functional characterization, and structural analysis of an atypical l-threonate 3-dehydrogenase · PMID 41690594 · 35 records
• Identification, heterologous expression and characterization of a dye-decolorizing peroxidase of Pleurotus sapidus · PMID 28831735 · 4 records
• Identification, Heterologous Expression, and Functional Characterization of Bacillus subtilis YutF, a HAD Superfamily 5'-Nucleotidase with Broad Substrate Specificity · PMID 27907199 · 5 records
• Identification, recombinant expression, and biochemical characterization of a flavonol 3-O-glucosyltransferase clone from Citrus paradisi · PMID 19733370 · 4 records
• Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases · PMID 15153101 · 16 records
• Identifying latent enzyme activities: substrate ambiguity within modern bacterial sugar kinases · PMID 15157072 · 12 records
• Identity of dimeric dihydrodiol dehydrogenase as NADP(+)-dependent D-xylose dehydrogenase in pig liver · PMID 11306093 · 44 records
• IdsA is the major geranylgeranyl pyrophosphate synthase involved in carotenogenesis in Corynebacterium glutamicum · PMID 25181035 · 8 records
• Ile209 of Leishmania donovani xanthine phosphoribosyltransferase plays a key role in determining its purine base specificity · PMID 34268726 · 20 records
• Imidazole glycerol phosphate synthase from Thermotoga maritima. Quaternary structure, steady-state kinetics, and reaction mechanism of the bienzyme complex · PMID 11264293 · 6 records
• Immobilization of β-Agarase onto Ni-NTA Magnetic Nanoparticles for Efficient Production of Functional Neoagarooligosaccharides · PMID 42650472 · 2 records
• Immobilized Wild-Type and Mutant L‑Alanine Dehydrogenase from Thermus thermophilus Coupled with Formate Dehydrogenase for Asymmetric Synthesis of Noncanonical Amino Acids · PMID 42756822 · 8 records
• Immunohistochemical localization of guinea-pig leukotriene B4 12-hydroxydehydrogenase/15-ketoprostaglandin 13-reductase · PMID 11733004 · 2 records
• IMP-12, a new plasmid-encoded metallo-beta-lactamase from a Pseudomonas putida clinical isolate · PMID 12709317 · 12 records
• Impact of intra-subunit domain-domain interactions on creatine kinase activity and stability · PMID 16797013 · 18 records
• Impact of Mutating the Key Residues of a Bifunctional 5,10-Methylenetetrahydrofolate Dehydrogenase-Cyclohydrolase from Escherichia coli on Its Activities · PMID 25988590 · 13 records
• Impact of naturally occurring variants of HCV protease on the binding of different classes of protease inhibitors · PMID 16445277 · 16 records
• Impact of pseudouridylation, substrate fold, and degradosome organization on the endonuclease activity of RNase E · PMID 34341070 · 12 records
• Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase · PMID 12054490 · 13 records
• Implication for functions of the ectopic adipocyte copper amine oxidase (AOC3) from purified enzyme and cell-based kinetic studies · PMID 22238597 · 32 records
• Importance of glutamate 279 for the coenzyme binding of human glutamate dehydrogenase · PMID 12193607 · 12 records
• Importance of glutamate 87 and the substrate α-amine for the reaction catalyzed by D-arginine dehydrogenase · PMID 25637657 · 10 records
• Importance of Ile71 in β-actin on histidine methyltransferase SETD3 catalysis · PMID 35142326 · 9 records
• Importance of lysine-286 at the NADP site of glutamate dehydrogenase from Salmonella typhimurium · PMID 1510967 · 49 records
• Importance of product/reactant equilibration in the kinetics of the phosphoglucose isomerization reaction by differential stopped flow microcalorimetry · PMID 15158492 · 6 records
• Importance of the conserved residues in the peptidoglycan glycosyltransferase module of the class A penicillin-binding protein 1b of Escherichia coli · PMID 18701463 · 6 records
• Importance of the dimer-dimer interface for allosteric signal transduction and AMP cooperativity of pig kidney fructose-1,6-bisphosphatase. Site-specific mutagenesis studies of Glu-192 and Asp-187… · PMID 9030572 · 4 records
• Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase · PMID 20528921 · 56 records
• Importance of the prime subsites of the C1s protease of the classical complement pathway for recognition of substrates · PMID 14674770 · 44 records
• Importance of the three basic residues in the vicinity of the zinc-binding motifs for the activity of the yeast dipeptidyl peptidase III · PMID 24136327 · 9 records
• Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform · PMID 16510539 · 43 records
• Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes · PMID 15044002 · 6 records
• Improved activity of α-chymotrypsin in mixed micelles of cetyltrimethylammonium bromide (CTAB) and ionic liquids: a kinetic study resorting to sequential injection analysis · PMID 24703063 · 21 records
• Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site · PMID 15850394 · 15 records
• Improved Enzymatic Properties of Chitosanase CsnMY002 from Bacillus subtilis via Computational Design · PMID 40004057 · 3 records
• Improved expression, purification and characterization of VPR, a cold active subtilisin-like serine proteinase and the effects of calcium on expression and stability · PMID 30502512 · 5 records
• Improved genetic screening with zygosity detection through multiplex high-resolution melting curve analysis and biochemical characterisation for G6PD deficiency · PMID 40078033 · 10 records
• Improved hydrolysis of piperacillin by OXA-48-like R214G variants, a selective advantage under piperacillin-tazobactam exposure · PMID 42053451 · 24 records
• Improved specificity toward substrates with positively charged side chains by site-directed mutagenesis of the L-lactate dehydrogenase of Bacillus stearothermophilus · PMID 7703235 · 25 records
• Improved thermostability and enzyme activity of a recombinant phyA mutant phytase from Aspergillus niger N25 by directed evolution and site-directed mutagenesis · PMID 29108630 · 8 records
• Improvement of catalytical properties of two invertases highly tolerant to sucrose after expression in Pichia pastoris. Effect of glycosylation on enzyme properties · PMID 26777250 · 4 records
• Improvement of Selenomonas ruminantium β-xylosidase thermal stability by replacing buried free cysteines via site directed mutagenesis · PMID 31220489 · 5 records
• Improvement of thermostable aldehyde dehydrogenase by directed evolution for application in Synthetic Cascade Biomanufacturing · PMID 24034429 · 6 records
• Improving activity of GenB3 and GenB4 in gentamicin dideoxygenation biosynthesis by semi-rational engineering · PMID 40016797 · 6 records
• Improving catalytic performance of an arylacetonitrilase by semirational engineering · PMID 28687857 · 8 records
• Improving glyphosate oxidation activity of glycine oxidase from Bacillus cereus by directed evolution · PMID 24223901 · 24 records
• Improving low-temperature catalysis in the hyperthermostable Pyrococcus furiosus beta-glucosidase CelB by directed evolution · PMID 10736164 · 28 records
• Improving the Activity and Stability of Human Galactokinase for Therapeutic and Biotechnological Applications · PMID 29505688 · 60 records
• Improving the catalytic activity of hyperthermophilic Pyrococcus horikoshii prolidase for detoxification of organophosphorus nerve agents over a broad range of temperatures · PMID 22162664 · 5 records
• Improving the catalytic activity of hyperthermophilic Pyrococcus prolidases for detoxification of organophosphorus nerve agents over a broad range of temperatures · PMID 20422176 · 12 records
• Improving the catalytic characteristics of phenolic acid decarboxylase from Bacillus amyloliquefaciens by the engineering of N-terminus and C-terminus · PMID 34311732 · 28 records
• Improving the catalytic efficiency of a meta-cleavage product hydrolase (CumD) from Pseudomonas fluorescens IP01 · PMID 16844437 · 33 records
• Improving the catalytic efficiency of Bacillus pumilus CotA-laccase by site-directed mutagenesis · PMID 27826721 · 12 records
• Improving the decolorization for textile dyes of a metagenome-derived alkaline laccase by directed evolution · PMID 21523474 · 8 records
• Improving the hydrophilic microenvironment surrounding the catalytic site of fructosyltransferase enhances its catalytic ability · PMID 40011254 · 2 records
• Improving the promiscuous nerve agent hydrolase activity of a thermostable archaeal lactonase · PMID 20667718 · 12 records
• Improving the thermostability and activity of Melanocarpus albomyces cellobiohydrolase Cel7B · PMID 19148633 · 10 records
• Improving thermostability and catalytic activity of pyranose 2-oxidase from Trametes multicolor by rational and semi-rational design · PMID 19143837 · 54 records
• Improving upon nature: active site remodeling produces highly efficient aldolase activity toward hydrophobic electrophilic substrates · PMID 22316217 · 16 records
• In Salmonella enterica, the sirtuin-dependent protein acylation/deacylation system (SDPADS) maintains energy homeostasis during growth on low concentrations of acetate · PMID 21306440 · 4 records
• In search of sustainable chemical processes: cloning, recombinant expression, and functional characterization of the 7α- and 7β-hydroxysteroid dehydrogenases from Clostridium absonum · PMID 22198717 · 13 records
• In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols · PMID 42522273 · 8 records
• In silico and in vitro investigations of the drug-drug interaction mechanisms between fludarabine and busulfan · PMID 41883506 · 3 records
• In Silico Optimization of a Bifunctional Lipase-Polyethylene Terephthalate (PET) Hydrolase for Enhanced PET and Lipid Hydrolysis · PMID 42214808 · 16 records
• In vitro activation of NAD-dependent alcohol dehydrogenases by Nudix hydrolases is more widespread than assumed · PMID 24928437 · 18 records
• In vitro and in vivo interactions of ferredoxin-NADP+ reductases in Pseudomonas putida · PMID 19122206 · 24 records
• In vitro characterization of a recombinant Blh protein from an uncultured marine bacterium as a beta-carotene 15,15'-dioxygenase · PMID 19366683 · 5 records
• In vitro characterization of N-terminal truncated EpsC from Bacillus subtilis 168, a UDP-N-acetylglucosamine 4,6-dehydratase · PMID 30222950 · 8 records
• In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes · PMID 16076215 · 21 records
• In vitro characterization of the catalytic domain of human histone deacetylase 5 · PMID 41760657 · 3 records
• In vitro kinetic analysis of substrate specificity in enterobactin biosynthetic lower pathway enzymes provides insight into the biochemical function of the hot dog-fold thioesterase EntH · PMID 19119850 · 12 records
• In vitro mutagenesis of Escherichia coli citrate synthase to clarify the locations of ligand binding sites · PMID 3276685 · 9 records
• In vitro mutagenesis studies at the arginine residues of adenylate kinase. A revised binding site for AMP in the X-ray-deduced model · PMID 2157484 · 14 records
• In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system · PMID 17962372 · 24 records
• In vitro processing of HIV-1 nucleocapsid protein by the viral proteinase: effects of amino acid substitutions at the scissile bond in the proximal zinc finger sequence · PMID 15065874 · 9 records
• In vitro reconstitution of an NADPH-dependent superoxide reduction pathway from Pyrococcus furiosus · PMID 15746356 · 5 records
• In vivo and in vitro analyses of single-amino acid variants of the Salmonella enterica phosphotransacetylase enzyme provide insights into the function of its N-terminal domain · PMID 17339319 · 12 records
• In vivo role of aldehyde reductase · PMID 22820017 · 10 records
• Inactivation of an aminoaldehyde dehydrogenase is responsible for fragrance in rice · PMID 18704694 · 8 records
• Inactivation of copper-containing amine oxidases by turnover products · PMID 14686927 · 9 records
• Inactivation of mesotrypsin by chymotrypsin C prevents trypsin inhibitor degradation · PMID 32014997 · 22 records
• Inactivation of microbial arginine deiminases by L-canavanine · PMID 18205354 · 9 records
• Incorporation of nucleoside probes opposite O⁶-methylguanine by Sulfolobus solfataricus DNA polymerase Dpo4: importance of hydrogen bonding · PMID 23959784 · 7 records
• Increase in D-tagatose production rate by site-directed mutagenesis of L-arabinose isomerase from Geobacillus thermodenitrificans · PMID 16489490 · 42 records
• Increase of Bacillus badius Phenylalanine dehydrogenase specificity towards phenylalanine substrate by site-directed mutagenesis · PMID 29051071 · 8 records
• Increased D-allose production by the R132E mutant of ribose-5-phosphate isomerase from Clostridium thermocellum · PMID 21132286 · 7 records
• Increased productivity of L-2-aminobutyric acid and total turnover number of NAD⁺/NADH in a one-pot system through enhanced thermostability of L-threonine deaminase · PMID 30259222 · 14 records
• Increased structural flexibility at the active site of a fluorophore-conjugated beta-lactamase distinctively impacts its binding toward diverse cephalosporin antibiotics · PMID 21705325 · 3 records
• Increased Turnover at Limiting O2 Concentrations by the Thr(387) → Ala Variant of HIF-Prolyl Hydroxylase PHD2 · PMID 25857330 · 10 records
• Increasing methotrexate resistance by combination of active-site mutations in human dihydrofolate reductase · PMID 17868689 · 11 records
• Increasing the catalytic activity of Bilirubin oxidase from Bacillus pumilus: Importance of host strain and chaperones proteins · PMID 27165502 · 2 records
• Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalytic fidelity · PMID 20476774 · 14 records
• Increasing the reaction rate of hydroxynitrile lyase from Hevea brasiliensis toward mandelonitrile by copying active site residues from an esterase that accepts aromatic esters · PMID 25044660 · 38 records
• Increasing the Thermostable Sugar-1-Phosphate Nucleotidylyltransferase Activities of the Archaeal ST0452 Protein through Site Saturation Mutagenesis of the 97th Amino Acid Position · PMID 27864169 · 8 records
• Increasing thermostability of the key photorespiratory enzyme glycerate 3-kinase by structure-based recombination · PMID 39550762 · 16 records
• Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2 · PMID 14625277 · 8 records
• Indispensable residue for uridine binding in the uridine-cytidine kinase family · PMID 28955773 · 29 records
• Individual variation in hepatic aldehyde oxidase activity · PMID 11569919 · 28 records
• Indoleglycerol phosphate synthase-phosphoribosyl anthranilate isomerase: comparison of the bifunctional enzyme from Escherichia coli with engineered monofunctional domains · PMID 7727400 · 12 records
• Inducible aldehyde dehydrogenases from rat liver cytosol · PMID 4002223 · 27 records
• Influence of a family 29 carbohydrate binding module on the activity of galactose oxidase from Fusarium graminearum · PMID 26518347 · 15 records
• Influence of moderate temperatures on myristoyl-CoA metabolism and acyl-CoA thioesterase activity in the psychrophilic antarctic yeast Rhodotorula aurantiaca · PMID 11279019 · 7 records
• Influence of pH on the Mn2+ activation of and binding to yeast enolase: a functional study · PMID 1536857 · 10 records
• Influence of polyols on the stability and kinetic parameters of invertase from Candida utilis: correlation with the conformational stability and activity · PMID 19020964 · 11 records
• Influence of substrate structure on the catalytic efficiency of hydroxysteroid sulfotransferase STa in the sulfation of alcohols · PMID 8924618 · 33 records
• Influencing the monophenolase/diphenolase activity ratio in tyrosinase · PMID 23305929 · 6 records
• InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis · PMID 30217823 · 14 records
• Inhibition and alternate substrate studies on the mechanism of carbapenam synthetase from Erwinia carotovora · PMID 12820893 · 12 records
• Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal · PMID 22819785 · 5 records
• Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds · PMID 25499551 · 8 records
• Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid · PMID 10869170 · 10 records
• Inhibition of L-threonine dehydrogenase from Trypanosoma cruzi reduces glycine and acetate production and interferes with parasite growth and viability · PMID 39675710 · 6 records
• Inhibition of methionyl-tRNA synthetase by REP8839 and effects of resistance mutations on enzyme activity · PMID 19015366 · 43 records
• Inhibition of Recombinant Aldose-6-Phosphate Reductase from Peach Leaves by Hexose-Phosphates, Inorganic Phosphate and Oxidants · PMID 28011870 · 4 records
• Inhibition of the Escherichia coli pyruvate dehydrogenase complex E1 subunit and its tyrosine 177 variants by thiamin 2-thiazolone and thiamin 2-thiothiazolone diphosphates. Evidence for reversible… · PMID 11583990 · 6 records
• Inhibitor-sensitive AmpC beta-lactamase variant produced by an Escherichia coli clinical isolate resistant to oxyiminocephalosporins and cephamycins · PMID 15215122 · 14 records
• Inhibitory effects of kynurenic acid, a tryptophan metabolite, and its derivatives on cytosolic sulfotransferases · PMID 19548878 · 37 records
• Inhibitory substrate binding site of human indoleamine 2,3-dioxygenase · PMID 19737010 · 6 records
• Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis · PMID 17402747 · 17 records
• Initial-rate kinetics of the flavin reductase reaction catalysed by human biliverdin-IXbeta reductase (BVR-B) · PMID 10620517 · 9 records
• Insertion of the Fe_B cofactor in cNORs lacking metal inserting chaperones · PMID 39927524 · 5 records
• Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans · PMID 26899032 · 5 records
• Insight into stability of CotA laccase from the spore coat of Bacillus subtilis · PMID 18031270 · 3 records
• Insight into substrate recognition and catalysis by the human neuraminidase 3 (NEU3) through molecular modeling and site-directed mutagenesis · PMID 20511247 · 7 records
• Insight into the Highly Conserved and Differentiated Cofactor-Binding Sites of meso-Diaminopimelate Dehydrogenase StDAPDH · PMID 30807172 · 15 records
• Insight into the mechanism of galactokinase: Role of a critical glutamate residue and helix/coil transitions · PMID 27789348 · 10 records
• Insight into the potential factors influencing the catalytic direction in cellobiose 2-epimerase by crystallization and mutagenesis · PMID 33135681 · 11 records
• Insight into the structural flexibility and function of Mycobacterium tuberculosis isocitrate lyase · PMID 25576828 · 4 records
• Insight of host immune evasion mediated by two variants of group a Streptococcus Mac protein · PMID 15466462 · 11 records
• Insights into Domain Organization and Regulatory Mechanism of Cystathionine Beta-Synthase from Toxoplasma gondii · PMID 35897745 · 4 records
• Insights into the catalytic mechanism of formate dehydrogenases from different microbial sources · PMID 41784227 · 12 records
• Insights into the catalytic mechanism of type VI sulfide:quinone oxidoreductases · PMID 33202220 · 6 records
• Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation · PMID 16953590 · 10 records
• Insights into the FMNAT Active Site of FAD Synthase: Aromaticity is Essential for Flavin Binding and Catalysis · PMID 32466340 · 26 records
• Insights into the function of RifI2: structural and biochemical investigation of a new shikimate dehydrogenase family protein · PMID 23142411 · 10 records
• Insights into the functional architecture of the catalytic center of a maize beta-glucosidase Zm-p60.1 · PMID 11706179 · 14 records
• Insights into the mechanism of dihydropyrimidine dehydrogenase from site-directed mutagenesis targeting the active site loop and redox cofactor coordination · PMID 20831907 · 11 records
• Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates · PMID 12960159 · 4 records
• Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates · PMID 21087925 · 3 records
• Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies · PMID 11148033 · 4 records
• Insights into the reaction mechanism of the diisopropyl fluorophosphatase from Loligo vulgaris by means of kinetic studies, chemical modification and site-directed mutagenesis · PMID 11295437 · 7 records
• Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum · PMID 18560156 · 15 records
• Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young · PMID 15677479 · 18 records
• Insights into the substrate specificity of plant peptide deformylase, an essential enzyme with potential for the development of novel biotechnology applications in agriculture · PMID 18412546 · 6 records
• Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies · PMID 17052977 · 71 records
• Integral role of the I'-helix in the function of the "inactive" C-terminal domain of catalase-peroxidase (KatG) · PMID 23084782 · 12 records
• Integrated characterization of six sesquiterpene synthases unravels diversified terpene biosynthesis in the mint species Leucosceptrum canum · PMID 42131745 · 6 records
• Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli · PMID 12732651 · 5 records
• Inter-domain communication in the dimeric DEAD-box helicase Hera from T. thermophilus and implications for the mechanism of RNA unwinding · PMID 39995044 · 20 records
• Inter-domain electron transfer in cellobiose dehydrogenase: modulation by pH and divalent cations · PMID 25913436 · 10 records
• Interaction between the lipoamide-containing H-protein and the lipoamide dehydrogenase (L-protein) of the glycine decarboxylase multienzyme system. 1. Biochemical studies · PMID 10806385 · 9 records
• Interaction of dopamine beta-mono-oxygenase with substituted imidazoles and pyrazoles. Catalysis and inhibition · PMID 3593236 · 2 records
• Interactions across the interface contribute the stability of homodimeric 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase · PMID 19683506 · 4 records
• Interactions at the 2 and 5 positions of 5-phosphoribosyl pyrophosphate are essential in Salmonella typhimurium quinolinate phosphoribosyltransferase · PMID 20047307 · 17 records
• Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase · PMID 14698288 · 23 records
• Interactions between serine acetyltransferase and O-acetylserine (thiol) lyase in higher plants--structural and kinetic properties of the free and bound enzymes · PMID 9692924 · 9 records
• Interactions of a family 18 chitinase with the designed inhibitor HM508 and its degradation product, chitobiono-delta-lactone · PMID 14597613 · 4 records
• Interactions of quinones with thioredoxin reductase: a challenge to the antioxidant role of the mammalian selenoprotein · PMID 14604985 · 28 records
• Interconversion of a pair of active-site residues in Escherichia coli cystathionine gamma-synthase, E. coli cystathionine beta-lyase, and Saccharomyces cerevisiae cystathionine gamma-lyase and… · PMID 19370061 · 24 records
• Interdomain contacts in flavocytochrome b(2), a mutational analysis · PMID 19821613 · 27 records
• Interfacial Redox Recycling Nanocatalysts with Ultrahigh Peroxidase Activity for Colorimetric Sensing Applications · PMID 42311319 · 1 record
• Intermediate instability at high temperature leads to low pathway efficiency for an in vitro reconstituted system of gluconeogenesis in Sulfolobus solfataricus · PMID 23865479 · 10 records
• Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate… · PMID 15835904 · 14 records
• Interplay between amino acid residues at positions 192 and 115 in modulating hydrolytic activities of human paraoxonase 1 · PMID 25107406 · 13 records
• Interplay between conformational dynamics and substrate binding regulates enzymatic activity: a single-molecule FRET study · PMID 39877815 · 7 records
• Interplay between ion binding and catalysis in the thioredoxin-coupled arsenate reductase family · PMID 16797027 · 14 records
• Interplay of isoprenoid and peptide substrate specificity in protein farnesyltransferase · PMID 16101305 · 11 records
• Intra-subunit residue interactions from the protein surface to the active site of glutathione S-transferase AdGSTD3-3 impact on structure and enzyme properties · PMID 15705499 · 8 records
• Intracellular β-glucosidase regulates cellulase expression and development in Aspergillus nidulans · PMID 42082762 · 6 records
• Intrinsic isomerase activity of medium-chain acyl-CoA dehydrogenase · PMID 15850406 · 13 records
• Inversion of enantioselectivity of asymmetric biocatalytic decarboxylation by site-directed mutagenesis based on the reaction mechanism · PMID 15700067 · 8 records
• Inversion of stereospecificity of vanillyl-alcohol oxidase · PMID 10920192 · 3 records
• Inversion of the substrate specificity of yeast alcohol dehydrogenase · PMID 8463307 · 102 records
• Investigating a catalytic mechanism of hyperthermophilic L-threonine dehydrogenase from Pyrococcus horikoshii · PMID 18390572 · 16 records
• Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca · PMID 20703875 · 32 records
• Investigating the mechanism of ADP-forming acetyl-CoA synthetase from the protozoan parasite Entamoeba histolytica · PMID 28129670 · 60 records
• Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity · PMID 17145127 · 36 records
• Investigating the roles of putative active site residues in the oxalate decarboxylase from Bacillus subtilis · PMID 17459326 · 12 records
• Investigation into the Mode of Phosphate Activation in the 4-Hydroxy-4-Methyl-2-Oxoglutarate/4-Carboxy-4-Hydroxy-2-Oxoadipate Aldolase from Pseudomonas putida F1 · PMID 27741265 · 22 records
• Investigation of conserved acidic residues in 3-hydroxy-3-methylglutaryl-CoA lyase: implications for human disease and for functional roles in a family of related proteins · PMID 12874287 · 8 records
• Investigation of metal binding and activation of Escherichia coli glyoxalase I: kinetic, thermodynamic and mutagenesis studies · PMID 14556652 · 4 records
• Investigation of pyrophosphate versus ATP substrate selection in the Entamoeba histolytica acetate kinase · PMID 28724909 · 22 records
• Investigation of the arylnitroso reductase activity of pig liver aldehyde reductase · PMID 3527154 · 5 records
• Investigation of the first step of biotin biosynthesis in Bacillus sphaericus. Purification and characterization of the pimeloyl-CoA synthase, and uptake of pimelate · PMID 1445232 · 4 records
• Investigation of the functional hot-spot residues of an enzyme by real-time monitoring of the enzymatic reaction using NMR and computational approaches · PMID 41530325 · 3 records
• Investigation of the Methanosarcina thermophila acetate kinase mechanism by fluorescence quenching · PMID 17999468 · 20 records
• Investigation of the pH-dependent electron transfer mechanism of ascomycetous class II cellobiose dehydrogenases on electrodes · PMID 22471986 · 180 records
• Investigation of the proton relay system operative in human cystosolic aminopeptidase P · PMID 29351301 · 6 records
• Investigation of the role of Arg301 identified in the X-ray structure of phosphite dehydrogenase · PMID 22564138 · 32 records
• Investigation of the role of conserved residues Ser13, Asn48 and Pro49 in the catalytic mechanism of the tau class glutathione transferase from Glycine max · PMID 19879385 · 6 records
• Investigation of the roles of catalytic residues in serotonin N-acetyltransferase · PMID 11884405 · 19 records
• Investigations of Accessibility of T2/T3 Copper Center of Two-Domain Laccase from Streptomyces griseoflavus Ac-993 · PMID 31261802 · 8 records
• Involvement of a flavosemiquinone in the enzymatic oxidation of nitroalkanes catalyzed by 2-nitropropane dioxygenase · PMID 15582992 · 26 records
• Involvement of conserved asparagine and arginine residues from the N-terminal region in the catalytic mechanism of rat liver and Trypanosoma cruzi tyrosine aminotransferases · PMID 12717026 · 30 records
• Involvement of glutamate 399 and lysine 192 in the mechanism of human liver mitochondrial aldehyde dehydrogenase · PMID 9228057 · 16 records
• Involvement of ionizable groups in catalysis of human liver glycolate oxidase · PMID 19758989 · 22 records
• Involvement of serine 74 in the enzyme-coenzyme interaction of rat liver mitochondrial aldehyde dehydrogenase · PMID 8043582 · 33 records
• Involvement of subdomain II in the recognition of acetyl-CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius · PMID 32897601 · 12 records
• Involvement of the chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase sequence His444-Arg-Glu-Arg in modulation of the bisphosphatase activity by its kinase domain · PMID 11439102 · 58 records
• Involvement of the pyrophosphate and the 2'-phosphate binding regions of ferredoxin-NADP+ reductase in coenzyme specificity · PMID 14500716 · 24 records
• Iodotyrosine deiodinase: a unique flavoprotein present in organisms of diverse phyla · PMID 24153409 · 7 records
• Irreversible inhibition of the Mycobacterium tuberculosis beta-lactamase by clavulanate · PMID 17915954 · 17 records
• Is rat an appropriate animal model to study the involvement of D-serine catabolism in schizophrenia? Insights from characterization of D-amino acid oxidase · PMID 21981077 · 8 records
• Isocitrate dehydrogenase from Streptococcus mutans: biochemical properties and evaluation of a putative phosphorylation site at Ser102 · PMID 23484056 · 10 records
• Isocitrate dehydrogenase of Plasmodium falciparum · PMID 12694190 · 3 records
• Isoflavone Malonyltransferases GmIMaT1 and GmIMaT3 Differently Modify Isoflavone Glucosides in Soybean (Glycine max) under Various Stresses · PMID 28559900 · 8 records
• Isoform-Specific NO Synthesis by Arabidopsis thaliana Nitrate Reductase · PMID 30884848 · 10 records
• Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase · PMID 25647642 · 3 records
• Isolation and analysis of mutated histidyl-tRNA synthetases from Escherichia coli · PMID 9266856 · 13 records
• Isolation and biochemical characterization of two soluble iron(III) reductases from Paracoccus denitrificans · PMID 14728682 · 10 records
• Isolation and characterization of a mutant dihydrofolate reductase-thymidylate synthase from methotrexate-resistant Leishmania cells · PMID 8144647 · 8 records
• Isolation and characterization of a new family 42 beta-galactosidase from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius: identification of the active site residues · PMID 18068682 · 8 records
• Isolation and characterization of a recombinant class C acid phosphatase from Sphingobium sp. RSMS strain · PMID 35242619 · 5 records
• Isolation and characterization of a thermostable F₄₂₀:NADPH oxidoreductase from Thermobifida fusca · PMID 28411200 · 28 records
• Isolation and characterization of an aldehyde dehydrogenase encoded by the aldB gene of Escherichia coli · PMID 15659684 · 9 records
• Isolation and characterization of dipeptidyl peptidase IV from human placenta · PMID 6751824 · 8 records
• Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization · PMID 17722885 · 26 records
• Isolation and characterization of human liver aldehyde dehydrogenase · PMID 4387261 · 6 records
• Isolation and characterization of mycophenolic acid-resistant mutants of inosine-5'-monophosphate dehydrogenase · PMID 8995388 · 18 records
• Isolation and Characterization of Reticuline N-Methyltransferase Involved in Biosynthesis of the Aporphine Alkaloid Magnoflorine in Opium Poppy · PMID 27634038 · 3 records
• Isolation and characterization of the acetyl-CoA synthetase from Penicillium chrysogenum. Involvement of this enzyme in the biosynthesis of penicillins · PMID 1347531 · 3 records
• Isolation and characterization of the cytosolic and chloroplastic 3-phosphoglycerate kinase from spinach leaves · PMID 16667463 · 32 records
• Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions · PMID 17261077 · 34 records
• Isolation and characterization of the human tRNA-(N1G37) methyltransferase (TRM5) and comparison to the Escherichia coli TrmD protein · PMID 15248782 · 23 records
• Isolation and characterization of the multiple charge isoforms of acyl-CoA synthetase from Escherichia coli · PMID 3907712 · 23 records
• Isolation and characterization of the stage-specific cytochrome b small subunit (CybS) of Ascaris suum complex II from the aerobic respiratory chain of larval mitochondria · PMID 12742584 · 12 records
• Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3 · PMID 1610806 · 25 records
• Isolation and characterization of the thrombin-like enzyme from Cryptelytrops albolabris (white-lipped tree viper) venom · PMID 21983189 · 5 records
• Isolation and characterization of thioredoxin and NADPH-dependent thioredoxin reductase from tomato (Solanum lycopersicum) · PMID 22027005 · 4 records
• Isolation and characterization of three alcohol dehydrogenase isozymes from Syrian golden hamsters · PMID 8730210 · 29 records
• Isolation and Characterization of Three New Monoterpene Synthases from Artemisia annua · PMID 27242840 · 3 records
• Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis · PMID 19098286 · 9 records
• Isolation and functional characterization of two Caffeoyl Coenzyme A 3-O-methyltransferases from the fern species Polypodiodes amoena · PMID 30685696 · 6 records
• Isolation and properties of cytoplasmic alpha-glycerol 3-phosphate dehydrogenase from the pectoral muscle of the fruit bat, Eidolon helvum · PMID 12689513 · 8 records
• Isolation and purification of N-formylmethionine aminopeptidase from rat intestine · PMID 1547272 · 10 records
• Isolation of 3 beta,20 alpha-hydroxysteroid oxidoreductase from sheep fetal blood · PMID 3483295 · 2 records
• Isolation of glyoxalase II from two different compartments of rat liver mitochondria. Kinetic and immunochemical characterization of the enzymes · PMID 2804125 · 8 records
• Isolation of proteins with carbonyl reductase activity and prostaglandin-9-ketoreductase activity from chicken kidney · PMID 6761337 · 26 records
• Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase · PMID 16201766 · 12 records
• Isoleucine 259 and isoleucine 260 residues in Streptococcus gordonii soluble inorganic pyrophosphatase play an important role in enzyme activity · PMID 21450519 · 6 records
• Isoleucine 69 and valine 325 form a specificity pocket in human muscle creatine kinase · PMID 15504039 · 47 records
• Isoniazid activation defects in recombinant Mycobacterium tuberculosis catalase-peroxidase (KatG) mutants evident in InhA inhibitor production · PMID 12543676 · 14 records
• Isopentenyl diphosphate/dimethylallyl diphosphate-specific Nudix hydrolase from the methanogenic archaeon Methanosarcina mazei · PMID 34864834 · 4 records
• Isopropylmalate synthase regulatory domain removal abolishes feedback regulation at the expense of leucine homeostasis in plants · PMID 39869449 · 8 records
• Isospecific adenine DNA methyltransferases show distinct preferences towards DNA substrates · PMID 29844340 · 13 records
• Isotope and elemental effects indicate a rate-limiting methyl transfer as the initial step in the reaction catalyzed by Escherichia coli cyclopropane fatty acid synthase · PMID 15491158 · 9 records
• Isotope sensitive branching and kinetic isotope effects in the reaction of deuterated arachidonic acids with human 12- and 15-lipoxygenases · PMID 18547056 · 4 records
• Jasmonates meet fatty acids: functional analysis of a new acyl-coenzyme A synthetase family from Arabidopsis thaliana · PMID 18267944 · 9 records
• Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade · PMID 20940292 · 11 records
• Kemp Elimination Catalyzed by Naturally Occurring Aldoxime Dehydratases · PMID 28120515 · 6 records
• Ketopantoate hydroxymethyltransferase. II. Physical, catalytic, and regulatory properties · PMID 6463 · 7 records
• Key amino acid residues in the regulation of soluble methane monooxygenase catalysis by component B · PMID 12741818 · 19 records
• Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase · PMID 15581601 · 18 records
• Key residues controlling phenacetin metabolism by human cytochrome P450 2A enzymes · PMID 18779312 · 10 records
• KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate · PMID 18765691 · 9 records
• Kinetic alteration of a human dihydrodiol/3alpha-hydroxysteroid dehydrogenase isoenzyme, AKR1C4, by replacement of histidine-216 with tyrosine or phenylalanine · PMID 11104674 · 77 records
• Kinetic analysis and substrate specificity of Escherichia coli dimethyl sulfoxide reductase · PMID 8969520 · 36 records
• Kinetic analysis of 6-phosphogluconate dehydrogenase from bass liver: effects of temperature and pH on its catalytic function · PMID 3355163 · 2 records
• Kinetic analysis of a globin-coupled diguanylate cyclase, YddV: Effects of heme iron redox state, axial ligands, and heme distal mutations on catalysis · PMID 31520879 · 14 records
• Kinetic Analysis of a Globin-Coupled Histidine Kinase, AfGcHK: Effects of the Heme Iron Complex, Response Regulator, and Metal Cations on Autophosphorylation Activity · PMID 26212354 · 28 records
• Kinetic analysis of a new human ornithine carbamoyltransferase variant · PMID 7397202 · 30 records
• Kinetic analysis of an inhibitor-resistant variant of the OHIO-1 beta-lactamase, an SHV-family class A enzyme · PMID 9735103 · 12 records
• Kinetic analysis of correct nucleotide insertion by a Y-family DNA polymerase reveals conformational changes both prior to and following phosphodiester bond formation as detected by tryptophan… · PMID 18984592 · 2 records
• Kinetic analysis of Escherichia coli 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase, wild type and mutants, reveals roles of active site amino acids · PMID 15379557 · 47 records
• Kinetic analysis of oxidation of coumarins by human cytochrome P450 2A6 · PMID 15665333 · 14 records
• Kinetic analysis of phenylalanine dehydrogenase mutants designed for aliphatic amino acid dehydrogenase activity with guidance from homology-based modelling · PMID 14622249 · 48 records
• Kinetic analysis of Pseudomonas aeruginosa arginine deiminase mutants and alternate substrates provides insight into structural determinants of function · PMID 16430212 · 13 records
• Kinetic analysis of the effects of monovalent cations and divalent metals on the activity of Mycobacterium tuberculosis alpha-isopropylmalate synthase · PMID 16684501 · 10 records
• Kinetic and biochemical properties of high and low redox potential laccases from fungal and plant origin · PMID 20056172 · 52 records
• Kinetic and catalytic mechanisms of the methionine-derived glucosinolate biosynthesis enzyme methylthioalkylmalate synthase · PMID 39322014 · 14 records
• Kinetic and chemical characterization of aldehyde oxidation by fungal aryl-alcohol oxidase · PMID 19891608 · 31 records
• Kinetic and chemical mechanism of alpha-isopropylmalate synthase from Mycobacterium tuberculosis · PMID 16846242 · 13 records
• Kinetic and chemical mechanism of arylamine N-acetyltransferase from Mycobacterium tuberculosis · PMID 18795795 · 19 records
• Kinetic and crystallographic analysis of active site mutants of Escherichia coli gamma-aminobutyrate aminotransferase · PMID 15723541 · 53 records
• Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase · PMID 11591148 · 5 records
• Kinetic and crystallographic studies of Escherichia coli UDP-N-acetylmuramate:L-alanine ligase · PMID 8976565 · 24 records
• Kinetic and crystallographic studies on the active site Arg289Lys mutant of flavocytochrome b2 (yeast L-lactate dehydrogenase) · PMID 10727218 · 6 records
• Kinetic and functional analysis of L-threonine kinase, the PduX enzyme of Salmonella enterica · PMID 19509296 · 26 records
• Kinetic and inhibition studies of cinnamoyl-CoA reductase 1 from Arabidopsis thaliana · PMID 16122934 · 6 records
• Kinetic and inhibition studies of dihydroxybenzoate-AMP ligase from Escherichia coli · PMID 20359185 · 7 records
• Kinetic and mechanistic characterization of recombinant Lactobacillus viridescens FemX (UDP-N-acetylmuramoyl pentapeptide-lysine N6-alanyltransferase) · PMID 12679335 · 15 records
• Kinetic and mechanistic studies of a cell cycle protein phosphatase Cdc14 · PMID 15128740 · 37 records
• Kinetic and mechanistic studies of prolyl oligopeptidase from the hyperthermophile Pyrococcus furiosus · PMID 11278687 · 11 records
• Kinetic and molecular analysis of 5-epiaristolochene 1,3-dihydroxylase, a cytochrome P450 enzyme catalyzing successive hydroxylations of sesquiterpenes · PMID 15522862 · 12 records
• Kinetic and molecular properties of Bacillus subtilis IBTC-3 subtilisin · PMID 15649780 · 13 records
• Kinetic and mutagenic studies of the role of the active site residues Asp-50 and Glu-327 of Escherichia coli glutamine synthetase · PMID 7904829 · 48 records
• Kinetic and mutation analyses of aspartate kinase from Thermus flavus · PMID 16232547 · 56 records
• Kinetic and pH studies on human phenylethanolamine N-methyltransferase · PMID 24018397 · 4 records
• Kinetic and redox properties of MnP II, a major manganese peroxidase isoenzyme from Panus tigrinus CBS 577.79 · PMID 19578878 · 11 records
• Kinetic and site-directed mutagenesis studies of the cysteine residues of bovine low molecular weight phosphotyrosyl protein phosphatase · PMID 8132604 · 19 records
• Kinetic and spectroscopic characterization of the H178A methionyl aminopeptidase from Escherichia coli · PMID 12755633 · 8 records
• Kinetic and spectroscopic studies on the quercetin 2,3-dioxygenase from Bacillus subtilis · PMID 16411777 · 6 records
• Kinetic and stability properties of Penicillium chrysogenum ATP sulfurylase missing the C-terminal regulatory domain · PMID 14613928 · 50 records
• Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed… · PMID 17902707 · 10 records
• Kinetic and stereochemical comparison of wild-type and active-site K145Q mutant enzyme of bacterial D-amino acid transaminase · PMID 8463224 · 18 records
• Kinetic and structural analysis for potent antifolate inhibition of Pneumocystis jirovecii, Pneumocystis carinii, and human dihydrofolate reductases and their active-site variants · PMID 23545530 · 51 records
• Kinetic and structural analysis of human ALDH9A1 · PMID 30914451 · 13 records
• Kinetic and structural analysis of mutant Escherichia coli dihydroorotases: a flexible loop stabilizes the transition state · PMID 17711307 · 5 records
• Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2 · PMID 28419689 · 9 records
• Kinetic and structural characterisation of the ubiquinol-binding site and oxygen reduction by the trypanosomal alternative oxidase · PMID 32565080 · 38 records
• Kinetic and structural characterization for cofactor preference of succinic semialdehyde dehydrogenase from Streptococcus pyogenes · PMID 25256219 · 2 records
• Kinetic and Structural Characterization of a Flavin-Dependent Putrescine N-Hydroxylase from Acinetobacter baumannii · PMID 36314559 · 8 records
• Kinetic and structural characterization of a heterohexamer 4-oxalocrotonate tautomerase from Chloroflexus aurantiacus J-10-fl: implications for functional and structural diversity in the tautomerase… · PMID 20465238 · 14 records
• Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus · PMID 20868223 · 33 records
• Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members · PMID 20709352 · 8 records
• Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis · PMID 38944687 · 15 records
• Kinetic and structural characterization of urease active site variants · PMID 10913264 · 10 records
• Kinetic and structural evidence for the importance of Tyr236 for the integrity of the Mo active site in a bacterial sulfite dehydrogenase · PMID 16893171 · 8 records
• Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin · PMID 20835842 · 22 records
• Kinetic and structural insights into enzymatic mechanism of succinic semialdehyde dehydrogenase from Cyanothece sp. ATCC51142 · PMID 32966327 · 20 records
• Kinetic and structural properties of triosephosphate isomerase from Helicobacter pylori · PMID 17957775 · 5 records
• Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase · PMID 19351586 · 6 records
• Kinetic and thermodynamic analysis of the interaction of cations with dialkylglycine decarboxylase · PMID 15109259 · 11 records
• Kinetic characterisation of a dye decolourising peroxidase from Streptomyces lividans: new insight into the mechanism of anthraquinone dye decolourisation · PMID 28695933 · 9 records
• Kinetic characteristics of phosphofructokinase from Bacillus stearothermophilus: MgATP nonallosterically inhibits the enzyme · PMID 8136379 · 14 records
• Kinetic characterization and quaternary structure of glutamate racemase from the periodontal anaerobe Fusobacterium nucleatum · PMID 19772853 · 9 records
• Kinetic characterization and structure analysis of an altered polyol dehydrogenase with d-lactate dehydrogenase activity · PMID 33020946 · 48 records
• Kinetic characterization of acetone monooxygenase from Gordonia sp. strain TY-5 · PMID 30392152 · 15 records
• Kinetic characterization of amino acid activation by aminoacyl-tRNA synthetases using radiolabelled γ-[³²P]ATP · PMID 39344714 · 3 records
• Kinetic characterization of cholinesterases and a therapeutically valuable cocaine hydrolase for their catalytic activities against heroin and its metabolite 6-monoacetylmorphine · PMID 30080993 · 6 records
• Kinetic characterization of human phosphopantothenoylcysteine synthetase · PMID 19683078 · 6 records
• Kinetic characterization of lysine-specific metalloendopeptidases from Grifola frondosa and Pleurotus ostreatus fruiting bodies · PMID 9644258 · 13 records
• Kinetic characterization of methionine gamma-lyases from the enteric protozoan parasite Entamoeba histolytica against physiological substrates and trifluoromethionine, a promising lead compound… · PMID 18199285 · 21 records
• Kinetic characterization of mitochondrial malate dehydrogenase from Dictyostelium discoideum · PMID 7142959 · 8 records
• Kinetic characterization of recombinant human cytosolic phosphoenolpyruvate carboxykinase with and without a His10-tag · PMID 17888579 · 10 records
• Kinetic characterization of the Escherichia coli oligopeptidase A (OpdA) and the role of the Tyr(607) residue · PMID 20513640 · 39 records
• Kinetic characterization of the oxidation of esculetin by polyphenol oxidase and peroxidase · PMID 17284853 · 8 records
• Kinetic characterization of the recombinant hyaluronan synthases from Streptococcus pyogenes and Streptococcus equisimilis · PMID 9933624 · 36 records
• Kinetic characterization of the soluble butane monooxygenase from Thauera butanivorans, formerly 'Pseudomonas butanovora' · PMID 19383682 · 9 records
• Kinetic characterization of the substrate specificity and mechanism of mushroom tyrosinase · PMID 10691963 · 18 records
• Kinetic characterization of thiolate anion formation and chemical catalysis of activated microsomal glutathione transferase 1 · PMID 15236595 · 9 records
• Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family · PMID 18559652 · 24 records
• Kinetic characterization of yeast alcohol dehydrogenases. Amino acid residue 294 and substrate specificity · PMID 3546317 · 40 records
• Kinetic characterization of yeast pyruvate carboxylase isozyme Pyc1 and the Pyc1 mutant, C249A · PMID 14744153 · 11 records
• Kinetic compartmentalization by unnatural reaction for itaconate production · PMID 36097012 · 14 records
• Kinetic control of nascent protein biogenesis by peptide deformylase · PMID 34961771 · 5 records
• Kinetic evaluation of glucose 1-phosphate analogues with a thymidylyltransferase using a continuous coupled enzyme assay · PMID 25408103 · 10 records
• Kinetic evidence for interdomain communication in the allosteric regulation of alpha-isopropylmalate synthase from Mycobacterium tuberculosis · PMID 19166329 · 13 records
• Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7… · PMID 15487984 · 40 records
• Kinetic investigations and stability studies of two Bothrops L-amino acid oxidases · PMID 30534149 · 14 records
• Kinetic mechanism and enantioselectivity of halohydrin dehalogenase from Agrobacterium radiobacter · PMID 12731879 · 12 records
• Kinetic mechanism and nucleotide specificity of NADH peroxidase · PMID 3124762 · 14 records
• Kinetic mechanism of AKT/PKB enzyme family · PMID 16540465 · 12 records
• Kinetic mechanism of Bacillus subtilis L-alanine dehydrogenase · PMID 6794611 · 6 records
• Kinetic mechanism of choline oxidase from Arthrobacter globiformis · PMID 12637017 · 6 records
• Kinetic mechanism of Escherichia coli isocitrate dehydrogenase · PMID 8369299 · 21 records
• Kinetic mechanism of glucose dehydrogenase from Halobacterium salinarum · PMID 10650712 · 4 records
• Kinetic mechanism of human inosine 5'-monophosphate dehydrogenase type II: random addition of substrates and ordered release of products · PMID 9214292 · 10 records
• Kinetic mechanism of indole-3-glycerol phosphate synthase · PMID 23214473 · 5 records
• Kinetic Mechanism of Nicotinamide N-Methyltransferase · PMID 30148963 · 8 records
• Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase · PMID 26902413 · 17 records
• Kinetic mechanism of protein N-terminal methyltransferase 1 · PMID 25771539 · 13 records
• Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines · PMID 15078100 · 15 records
• Kinetic mechanism of the endogenous lactate dehydrogenase activity of duck epsilon-crystallin · PMID 1989512 · 20 records
• Kinetic mechanism of the Rtt109-Vps75 histone acetyltransferase-chaperone complex · PMID 20560668 · 9 records
• Kinetic mechanism of the tRNA-modifying enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) · PMID 12731872 · 2 records
• Kinetic mechanism of uracil phosphoribosyltransferase from Escherichia coli and catalytic importance of the conserved proline in the PRPP binding site · PMID 10079076 · 8 records
• Kinetic mechanisms of Ca++/calmodulin dependent protein kinases · PMID 21081101 · 6 records
• Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum · PMID 10447682 · 49 records
• Kinetic mechanisms of glycine oxidase from Bacillus subtilis · PMID 12654003 · 6 records
• Kinetic mechanisms of polyphosphate glucokinase from Mycobacterium tuberculosis · PMID 8703950 · 11 records
• Kinetic mechanisms of the A and B isozymes of O-acetylserine sulfhydrylase from Salmonella typhimurium LT-2 using the natural and alternative reactants · PMID 8518286 · 16 records
• Kinetic modeling of beta-chloroprene metabolism: I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans · PMID 14976339 · 18 records
• Kinetic Parameters and Cytotoxic Activity of Recombinant Methionine γ-Lyase from Clostridium tetani, Clostridium sporogenes, Porphyromonas gingivalis and Citrobacter freundii · PMID 24303205 · 15 records
• Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1 · PMID 28684414 · 11 records
• Kinetic properties and ammonium-dependent regulation of cytosolic isoenzymes of glutamine synthetase in Arabidopsis · PMID 14757761 · 14 records
• Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Leishmania major · PMID 11420444 · 8 records
• Kinetic properties and metal content of the metallo-beta-lactamase CcrA harboring selective amino acid substitutions · PMID 10336469 · 24 records
• Kinetic properties and specificity of trimeric Plasmodium falciparum and human dUTPases · PMID 19879316 · 17 records
• Kinetic properties of bifunctional 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from spinach leaves · PMID 11856361 · 18 records
• Kinetic properties of four plasmid-mediated AmpC beta-lactamases · PMID 16189104 · 53 records
• Kinetic properties of fructose bisphosphate aldolase from Trypanosoma brucei compared to aldolase from rabbit muscle and Staphylococcus aureus · PMID 1857377 · 33 records
• Kinetic properties of human liver alcohol dehydrogenase: oxidation of alcohols by class I isoenzymes · PMID 6342669 · 144 records
• Kinetic properties of human placental glucose-6-phosphate dehydrogenase · PMID 11311853 · 8 records
• Kinetic properties of human thymidylate synthase, an anticancer drug target · PMID 12859954 · 3 records
• Kinetic properties of Mycobacterium tuberculosis bifunctional GlmU · PMID 21594607 · 4 records
• Kinetic properties of native and mutagenized isoforms of mitochondrial alcohol dehydrogenase III purified from Kluyveromyces lactis · PMID 15556281 · 24 records
• Kinetic properties of polymorphic variants and pathogenic mutants in human cystathionine gamma-lyase · PMID 18476726 · 10 records
• Kinetic properties of three isoforms of trypsin isolated from the pyloric caeca of chum salmon (Oncorhynchus keta) · PMID 17827714 · 24 records
• Kinetic properties of wild-type and altered recombinant amidases by the use of ion-selective electrode assay method · PMID 16792995 · 44 records
• Kinetic specificities of BPN' and Carlsberg subtilisins. Mapping the aromatic binding site · PMID 102640 · 49 records
• Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 · PMID 15153118 · 10 records
• Kinetic studies of AKR1B10, human aldose reductase-like protein: endogenous substrates and inhibition by steroids · PMID 19464995 · 60 records
• Kinetic studies of carboxypeptidase Y. I. Kinetic parameters for the hydrolysis of synthetic substrates · PMID 237004 · 47 records
• Kinetic studies of Mg(2+)-, Co(2+)- and Mn(2+)-activated D-xylose isomerases · PMID 1831974 · 174 records
• Kinetic studies of yeast nucleoside diphosphate kinase · PMID 5793714 · 6 records
• Kinetic studies on endo-beta-galactosidase by a novel colorimetric assay and synthesis of N-acetyllactosamine-repeating oligosaccharide beta-glycosides using its transglycosylation activity · PMID 12950254 · 9 records
• Kinetic studies on the enzyme (S)-hydroxynitrile lyase from hevea brasiliensis using initial rate methods and progress curve analysis · PMID 10099509 · 6 records
• Kinetic studies on the inhibition of creatine kinase activity by 3-butyl-1-phenyl-2-(phenyltelluro)oct-en-1-one in the cerebral cortex of rats · PMID 22884765 · 36 records
• KINETIC STUDIES ON THE REACTION CATALYZED BY PHOSPHOGLYCERATE KINASE. I. THE EFFECT OF MG2+ AND ADENOSINE 5'-TRIPHOSPHATE · PMID 14159303 · 5 records
• Kinetic study of sn-glycerol-1-phosphate dehydrogenase from the aerobic hyperthermophilic archaeon, Aeropyrum pernix K1 · PMID 11846799 · 10 records
• Kinetic study of thermostable L-threonine dehydrogenase from an archaeon Pyrococcus horikoshii · PMID 16233775 · 4 records
• Kinetic, computational, and phylogenetic characterisation of PA2125 from Pseudomonas aeruginosa PAO1: a hydroxybenzaldehyde dehydrogenase of the newly defined ALDH33 family · PMID 42713819 · 30 records
• Kinetic, Raman, NMR, and site-directed mutagenesis studies of the Pseudomonas sp. strain CBS3 4-hydroxybenzoyl-CoA thioesterase active site · PMID 12220180 · 11 records
• Kinetic, spectroscopic and thermodynamic characterization of the Mycobacterium tuberculosis adrenodoxin reductase homologue FprA · PMID 12614197 · 5 records
• Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus · PMID 29933553 · 6 records
• Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis · PMID 20851704 · 4 records
• Kinetically and Crystallographically Guided Mutations of a Benzoate CoA Ligase (BadA) Elucidate Mechanism and Expand Substrate Permissivity · PMID 26378464 · 25 records
• Kinetics and equilibrium of the inactivation of ornithine transcarbamylases by pyridoxal 5'-phosphate · PMID 16927 · 11 records
• Kinetics and inhibition studies of the L205R mutant of cAMP-dependent protein kinase involved in Cushing's syndrome · PMID 29632813 · 2 records
• Kinetics and mechanism of benzoylformate decarboxylase using 13C and solvent deuterium isotope effects on benzoylformate and benzoylformate analogues · PMID 3378056 · 6 records
• Kinetics and Predicted Structure of a Novel Xylose Reductase from Chaetomium thermophilum · PMID 30621365 · 8 records
• Kinetics and specificity of human liver aldehyde dehydrogenases toward aliphatic, aromatic, and fused polycyclic aldehydes · PMID 8605195 · 84 records
• Kinetics and stereochemistry of hydrolysis of an N-(phenylacetyl)-α-hydroxyglycine ester catalyzed by serine β-lactamases and DD-peptidases · PMID 22851054 · 8 records
• Kinetics and structural features of dimeric glutamine-dependent bacterial NAD⁺ synthetases suggest evolutionary adaptation to available metabolites · PMID 29581233 · 6 records
• Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes · PMID 28779158 · 12 records
• Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates · PMID 21177865 · 20 records
• Kinetics of human alcohol dehydrogenase with ring-oxidized retinoids: effect of Tween 80 · PMID 15369820 · 17 records
• Kinetics of turnover of cefotaxime by the Enterobacter cloacae P99 and GCl beta-lactamases: two free enzyme forms of the P99 beta-lactamase detected by a combination of pre- and post-steady state… · PMID 14992604 · 7 records
• Kinetics study of KPC-3, a plasmid-encoded class A carbapenem-hydrolyzing beta-lactamase · PMID 16251324 · 11 records
• Kinetics study reveals interconnected relationships of component activities in trifunctional RNA capping enzymes · PMID 42248456 · 10 records
• Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase · PMID 17595169 · 6 records
• Km defect in neuraminidase of dysmorphic type sialidosis with and without beta-galactosidase deficiency · PMID 6811161 · 32 records
• Kosmotropic salt activation and substrate specificity of poliovirus protease 3C · PMID 17002308 · 14 records
• L-allo-threonine aldolase with an H128Y/S292R mutation from Aeromonas jandaei DK-39 reveals the structural basis of changes in substrate stereoselectivity · PMID 24914980 · 8 records
• L-Arabinose degradation pathway in the haloarchaeon Haloferax volcanii involves a novel type of L-arabinose dehydrogenase · PMID 23949136 · 3 records
• L-Asparaginase from Erwinia Chrysanthemi 3937: cloning, expression and characterization · PMID 16984804 · 4 records
• l-Galactono-gamma-lactone dehydrogenase from Arabidopsis thaliana, a flavoprotein involved in vitamin C biosynthesis · PMID 18190525 · 10 records
• l-Galactose metabolism in Bacteroides vulgatus from the human gut microbiota · PMID 24963813 · 17 records
• L-Idose: an attractive substrate alternative to D-glucose for measuring aldose reductase activity · PMID 25528584 · 4 records
• L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase · PMID 21042731 · 32 records
• L-Malyl-coenzyme A lyase/beta-methylmalyl-coenzyme A lyase from Chloroflexus aurantiacus, a bifunctional enzyme involved in autotrophic CO(2) fixation · PMID 12374834 · 15 records
• L-Mandelate dehydrogenase from Rhodotorula graminis: cloning, sequencing and kinetic characterization of the recombinant enzyme and its independently expressed flavin domain · PMID 9639569 · 9 records
• L-serine and L-threonine dehydratase from Clostridium propionicum. Two enzymes with different prosthetic groups · PMID 8344301 · 3 records
• Laboratory-evolved vanillyl-alcohol oxidase produces natural vanillin · PMID 15169773 · 76 records
• Lactate dehydrogenase A exhibits sorbitol/fructose-related catalytic activity and contributes to polyol pathway metabolism in tumor cells · PMID 42548485 · 16 records
• Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis · PMID 37863926 · 9 records
• Lacto-N-biosidase encoded by a novel gene of Bifidobacterium longum subspecies longum shows unique substrate specificity and requires a designated chaperone for its active expression · PMID 23843461 · 4 records
• Lactonase-mediated inhibition of quorum sensing largely alters phenotypes, proteome, and antimicrobial activities in Burkholderia thailandensis E264 · PMID 37333853 · 12 records
• Lamprey fructose-1,6-bisphosphate aldolase: characterization of the muscle-type and non-muscle-type isozymes · PMID 9143366 · 8 records
• Lanthanide-Dependent Methanol Dehydrogenases of XoxF4 and XoxF5 Clades Are Differentially Distributed Among Methylotrophic Bacteria and They Reveal Different Biochemical Properties · PMID 29997591 · 18 records
• LccA, an archaeal laccase secreted as a highly stable glycoprotein into the extracellular medium by Haloferax volcanii · PMID 19966030 · 5 records
• Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity · PMID 26771178 · 4 records
• Leishmania UDP-sugar pyrophosphorylase: the missing link in galactose salvage? · PMID 19906649 · 12 records
• Lethal effects of a hyperactive dGTP triphosphohydrolase in E. coli · PMID 42234826 · 4 records
• Leucine 208 in human histamine N-methyltransferase emerges as a hotspot for protein stability rationalizing the role of the L208P variant in intellectual disability · PMID 27769936 · 7 records
• Leucyl-tRNA synthetase consisting of two subunits from hyperthermophilic bacteria Aquifex aeolicus · PMID 12196521 · 13 records
• Leukotriene A4 hydrolase: an anion activated peptidase · PMID 1536866 · 15 records
• Lid L11 of the glutamine amidotransferase domain of CTP synthase mediates allosteric GTP activation of glutaminase activity · PMID 15670165 · 24 records
• Ligand complex structures of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 and its conformational change · PMID 29511608 · 20 records
• Ligands of the Mn2+ bound to porcine mitochondrial NADP-dependent isocitrate dehydrogenase, as assessed by mutagenesis · PMID 15005617 · 14 records
• Linking coupled motions and entropic effects to the catalytic activity of 2-deoxyribose-5-phosphate aldolase (DERA) · PMID 29910900 · 21 records
• Lipoamidase is a multiple hydrolase · PMID 2222421 · 32 records
• Lipoamide dehydrogenase from human liver · PMID 4289186 · 5 records
• Lipopolysaccharide biosynthesis without the lipids: recognition promiscuity of Escherichia coli heptosyltransferase I · PMID 22059588 · 8 records
• Live-cell DNMT3A "catalysome" mapping using engineered methyl-transfer pathways · PMID 42770327 · 10 records
• Loblolly pine abietadienol/abietadienal oxidase PtAO (CYP720B1) is a multifunctional, multisubstrate cytochrome P450 monooxygenase · PMID 15911762 · 7 records
• Localization and characteristics of hexose 6-phosphate dehydrogenase (glucose dehydrogenase) · PMID 4169027 · 12 records
• Localization and functional analysis of the substrate specificity/catalytic domains of human M-form and P-form phenol sulfotransferases · PMID 9497349 · 18 records
• Location of the coenzyme binding site in the porcine mitochondrial NADP-dependent isocitrate dehydrogenase · PMID 15975917 · 16 records
• Locations and functional roles of conserved lysine residues in Salmonella typhimurium orotate phosphoribosyltransferase · PMID 7545005 · 60 records
• Long range communication between exosites 1 and 2 modulates thrombin function · PMID 19589779 · 12 records
• Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids · PMID 28209804 · 35 records
• Loop of Streptomyces Feruloyl Esterase Plays an Important Role in the Enzyme's Catalyzing the Release of Ferulic Acid from Biomass · PMID 29150515 · 14 records
• Loop-loop interactions govern multiple steps in indole-3-glycerol phosphate synthase catalysis · PMID 24403092 · 11 records
• Low efficiency IDO2 enzymes are conserved in lower vertebrates, whereas higher efficiency IDO1 enzymes are dispensable · PMID 25950090 · 18 records
• Lys-D48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase B of Lactococcus lactis · PMID 16624811 · 11 records
• Lys300 plays a major role in the catalytic mechanism of maize polyamine oxidase · PMID 16331971 · 15 records
• Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5 · PMID 10320345 · 7 records
• Lysine decarboxylase catalyzes the first step of quinolizidine alkaloid biosynthesis and coevolved with alkaloid production in leguminosae · PMID 22415272 · 12 records
• Lysine racemase from a lactic acid bacterium, Oenococcus oeni: structural basis of substrate specificity · PMID 23035128 · 20 records
• Lysine-21 of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase participates in substrate binding through charge-charge interaction · PMID 1304341 · 12 records
• Lysine-Specific Demethylase 1A (KDM1A/LSD1): Product Recognition and Kinetic Analysis of Full-Length Histones · PMID 26673564 · 3 records
• Lysophosphatidic acids are new substrates for the phosphatase domain of soluble epoxide hydrolase · PMID 22217705 · 10 records
• LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis · PMID 12482608 · 2 records
• Lytic Polysaccharide Monooxygenase from Talaromyces amestolkiae with an Enigmatic Linker-like Region: The Role of This Enzyme on Cellulose Saccharification · PMID 34948409 · 6 records
• M379A Mutant Tyrosine Phenol-lyase from Citrobacter freundii Has Altered Conformational Dynamics · PMID 35577764 · 11 records
• m⁶A RNA Degradation Products Are Catabolized by an Evolutionarily Conserved N⁶-Methyl-AMP Deaminase in Plant and Mammalian Cells · PMID 29884623 · 7 records
• Maize C4 NADP-malic enzyme. Expression in Escherichia coli and characterization of site-directed mutants at the putative nucleoside-binding sites · PMID 12562758 · 11 records
• Maize phenylalanine ammonia-lyase has tyrosine ammonia-lyase activity · PMID 9008393 · 4 records
• Maize phenylalanine ammonia-lyase produces (R)-β-tyrosine, a growth inhibitor for the parasitic weed Striga hermonthica · PMID 42480067 · 3 records
• Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members · PMID 10510318 · 28 records
• Malate dehydrogenase. Kinetic studies with meso-tartrate and 2-keto-3-hydroxysuccinate, comparison of the mitochondrial and supernatant pig heart enzymes · PMID 475389 · 12 records
• Malate dehydrogenases of leaf tissue from Spinacia oleracea: properties of three isoenzymes · PMID 5114926 · 18 records
• Maltose-forming α-amylase from the hyperthermophilic archaeon Pyrococcus sp. ST04 · PMID 23884203 · 4 records
• MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis · PMID 17369439 · 8 records
• Mammalian Arachidonic Acid 15-Lipoxygenases: Fed-Batch Fermentation, Enzyme Purification and Functional Characterization · PMID 42646335 · 6 records
• Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide… · PMID 3893542 · 139 records
• Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics · PMID 19804409 · 33 records
• Mannose foraging by Bacteroides thetaiotaomicron: structure and specificity of the beta-mannosidase, BtMan2A · PMID 17287210 · 24 records
• Many fructosamine 3-kinase homologues in bacteria are ribulosamine/erythrulosamine 3-kinases potentially involved in protein deglycation · PMID 17681011 · 17 records
• Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin… · PMID 22443469 · 20 records
• Mapping active site residues in glutamate-5-kinase. The substrate glutamate and the feed-back inhibitor proline bind at overlapping sites · PMID 17069808 · 21 records
• Mapping of ATP binding regions in poly(A) polymerases by photoaffinity labeling and by mutational analysis identifies a domain conserved in many nucleotidyltransferases · PMID 10595540 · 35 records
• Mapping the active site of meprin-A with peptide substrates and inhibitors · PMID 1883833 · 27 records
• Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases · PMID 34133730 · 10 records
• Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity · PMID 11278902 · 16 records
• Mass spectrometric characterization of a three-enzyme tandem reaction for assembly and modification of the novobiocin skeleton · PMID 15218104 · 4 records
• Measurement of incorporation kinetics of non-fluorescent native nucleotides by DNA polymerases using fluorescence microscopy · PMID 29036327 · 8 records
• Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus · PMID 18335995 · 18 records
• Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomallei · PMID 21393229 · 5 records
• Mechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia mallei · PMID 20055482 · 19 records
• Mechanism and regulation of mycobactin fatty acyl-AMP ligase FadD33 · PMID 23935107 · 7 records
• Mechanism and Structure of γ-Resorcylate Decarboxylase · PMID 29283551 · 4 records
• Mechanism and substrate recognition of 2-hydroxyethylphosphonate dioxygenase · PMID 21711001 · 8 records
• Mechanism and substrate recognition of human holo ACP synthase · PMID 18022563 · 10 records
• Mechanism for the hydrolysis of organophosphates by the bacterial phosphotriesterase · PMID 15134445 · 25 records
• Mechanism of 6-Hydroxynicotinate 3-Monooxygenase, a Flavin-Dependent Decarboxylative Hydroxylase Involved in Bacterial Nicotinic Acid Degradation · PMID 30810301 · 16 records
• Mechanism of adenylate kinase. The conserved aspartates 140 and 141 are important for transition state stabilization instead of substrate-induced conformational changes · PMID 8132532 · 16 records
• Mechanism of aminoglycoside 3'-phosphotransferase type IIIa: His188 is not a phosphate-accepting residue · PMID 8939691 · 16 records
• Mechanism of cobyrinic acid a,c-diamide synthetase from Salmonella typhimurium LT2 · PMID 15311923 · 43 records
• Mechanism of GlvA from Bacillus subtilis: a detailed kinetic analysis of a 6-phospho-alpha-glucosidase from glycoside hydrolase family 4 · PMID 17676871 · 30 records
• Mechanism of Human Nucleocytoplasmic Hexosaminidase D · PMID 27149221 · 14 records
• Mechanism of poly(A) polymerase: structure of the enzyme-MgATP-RNA ternary complex and kinetic analysis · PMID 17850751 · 26 records
• Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis · PMID 11581264 · 12 records
• Mechanism of rabbit muscle enolase: identification of the rate-limiting steps and the site of Li+ inhibition · PMID 8651685 · 5 records
• Mechanism of substrate recognition by botulinum neurotoxin serotype A · PMID 17244603 · 19 records
• Mechanism of the dihydroorotase reaction · PMID 15610022 · 12 records
• Mechanism of the family 1 beta-glucosidase from Streptomyces sp: catalytic residues and kinetic studies · PMID 11352732 · 37 records
• Mechanism of the Flavoprotein d-6-Hydroxynicotine Oxidase: Substrate Specificity, pH and Solvent Isotope Effects, and Roles of Key Active-Site Residues · PMID 31046245 · 20 records
• Mechanism of the insect enzyme, tyramine beta-monooxygenase, reveals differences from the mammalian enzyme, dopamine beta-monooxygenase · PMID 18032384 · 35 records
• Mechanism of the intramolecular Claisen condensation reaction catalyzed by MenB, a crotonase superfamily member · PMID 21830810 · 6 records
• Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site · PMID 21870810 · 15 records
• Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants · PMID 10933783 · 10 records
• Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 2. Substrate modeling and active site mutations · PMID 18627130 · 20 records
• Mechanism of the reaction catalyzed by dehydroascorbate reductase from spinach chloroplasts · PMID 12603325 · 8 records
• Mechanism of the reaction catalyzed by isoaspartyl dipeptidase from Escherichia coli · PMID 15882050 · 21 records
• Mechanism of U-insertion RNA editing in trypanosome mitochondria: characterization of RET2 functional domains by mutational analysis · PMID 20417643 · 9 records
• Mechanism-based inhibition of human persulfide dioxygenase by γ-glutamyl-homocysteinyl-glycine · PMID 29980601 · 5 records
• Mechanisms of interaction of Escherichia coli threonine synthase with substrates and inhibitors · PMID 7907888 · 2 records
• Mechanistic analysis of the argE-encoded N-acetylornithine deacetylase · PMID 10684608 · 16 records
• Mechanistic and Crystallographic Studies of Azoreductase AzoA from Bacillus wakoensis A01 · PMID 31967777 · 12 records
• Mechanistic and Molecular Dynamics Studies Reveal that Increased Loop 3 Mobility Alters Substrate Capture in an NADH:Quinone Oxidoreductase · PMID 41388968 · 4 records
• Mechanistic and structural analyses of the roles of active site residues in yeast polyamine oxidase Fms1: characterization of the N195A and D94N enzymes · PMID 23034052 · 10 records
• Mechanistic and structural analysis of a family 31 alpha-glycosidase and its glycosyl-enzyme intermediate · PMID 15501829 · 5 records
• Mechanistic characterization of N-formimino-L-glutamate iminohydrolase from Pseudomonas aeruginosa · PMID 17128965 · 10 records
• Mechanistic characterization of the MSDH (methylmalonate semialdehyde dehydrogenase) from Bacillus subtilis · PMID 16332250 · 10 records
• Mechanistic characterization of the tetraacyldisaccharide-1-phosphate 4'-kinase LpxK involved in lipid A biosynthesis · PMID 23464738 · 22 records
• Mechanistic features of lignin peroxidase-catalyzed oxidation of substituted phenols and 1,2-dimethoxyarenes · PMID 12857756 · 22 records
• Mechanistic features of Salmonella typhimurium propionate kinase (TdcD): insights from kinetic and crystallographic studies · PMID 23747922 · 7 records
• Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria · PMID 30677184 · 46 records
• Mechanistic insight into the substrate specificity of 1,2-β-oligoglucan phosphorylase from Lachnoclostridium phytofermentans · PMID 28198470 · 8 records
• Mechanistic insights from substrate preference in unsaturated glucuronyl hydrolase · PMID 24227702 · 10 records
• Mechanistic insights into the isochorismate pyruvate lyase activity of the catalytically promiscuous PchB from combinatorial mutagenesis and selection · PMID 16036918 · 25 records
• Mechanistic investigation of the endo-alpha-N-acetylgalactosaminidase from Streptococcus pneumoniae R6 · PMID 19788271 · 18 records
• Mechanistic role of each metal ion in Streptomyces dinuclear aminopeptidase: PEPTIDE hydrolysis and 7x10(10)-fold rate enhancement of phosphodiester hydrolysis · PMID 19879003 · 13 records
• Mechanistic roles of Ser-114, Tyr-155, and Lys-159 in 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni · PMID 15572373 · 11 records
• Mechanistic roles of Thr134, Tyr160, and Lys 164 in the reaction catalyzed by dTDP-glucose 4,6-dehydratase · PMID 11478886 · 10 records
• Mechanistic Studies of 1-Deoxy-D-Xylulose-5-Phosphate Synthase from Deinococcus radiodurans · PMID 29552677 · 10 records
• Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism · PMID 24989433 · 9 records
• Mechanistic studies of the role of a conserved histidine in a mammalian polyamine oxidase · PMID 22959971 · 25 records
• Mechanistic Studies of the Streptomyces bingchenggensis Aldolase-Dehydratase: Implications for Substrate and Reaction Specificity in the Acetoacetate Decarboxylase-like Superfamily · PMID 31524380 · 27 records
• Mechanistic studies of two dioxygenases in the methionine salvage pathway of Klebsiella pneumoniae · PMID 11371200 · 4 records
• Mechanistic studies on bovine cytosolic 5'-nucleotidase II, an enzyme belonging to the HAD superfamily · PMID 15606776 · 20 records
• Mechanistic studies on trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (Ent A) in the biosynthesis of the iron chelator enterobactin · PMID 2144454 · 15 records
• Mechanistic studies with 2-C-methyl-D-erythritol 4-phosphate synthase from Escherichia coli · PMID 15938625 · 3 records
• Mechanistic study of beta-xylosidase from Trichoderma koningii G-39 · PMID 10731699 · 9 records
• Mechanistic, mutational, and structural evaluation of a Taxus phenylalanine aminomutase · PMID 21361343 · 14 records
• Medium-long-chain chimeric human Acyl-CoA dehydrogenase: medium-chain enzyme with the active center base arrangement of long-chain Acyl-CoA dehydrogenase · PMID 8823175 · 18 records
• Menaquinone-specific turnover by Mycobacterium tuberculosis cytochrome bd is redox regulated by the Q-loop disulfide bond · PMID 39706268 · 3 records
• Mesaconase Activity of Class I Fumarase Contributes to Mesaconate Utilization by Burkholderia xenovorans · PMID 26070669 · 8 records
• Mesaconase/Fumarase FumD in Escherichia coli O157:H7 and Promiscuity of Escherichia coli Class I Fumarases FumA and FumB · PMID 26658641 · 18 records
• Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis · PMID 26013824 · 12 records
• Metabolic engineering of Saccharomyces cerevisiae for bioconversion of D-xylose to D-xylonate · PMID 22709678 · 9 records
• Metabolic enzymes from psychrophilic bacteria: challenge of adaptation to low temperatures in ornithine carbamoyltransferase from Moritella abyssi · PMID 12644485 · 9 records
• Metabolic mechanism of mannan in a ruminal bacterium, Ruminococcus albus, involving two mannoside phosphorylases and cellobiose 2-epimerase: discovery of a new carbohydrate phosphorylase… · PMID 23093406 · 43 records
• Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis · PMID 27513637 · 9 records
• Metabolic pathway promiscuity in the archaeon Sulfolobus solfataricus revealed by studies on glucose dehydrogenase and 2-keto-3-deoxygluconate aldolase · PMID 12824170 · 7 records
• Metabolic reprogramming promotes Staphylococcus aureus serum resistance · PMID 42228390 · 8 records
• Metabolic stability of alpha-methylated polyamine derivatives and their use as substitutes for the natural polyamines · PMID 15611107 · 18 records
• Metabolism of Oxo-Bile Acids and Characterization of Recombinant 12α-Hydroxysteroid Dehydrogenases from Bile Acid 7α-Dehydroxylating Human Gut Bacteria · PMID 29549099 · 12 records
• Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1 · PMID 15258110 · 10 records
• Metabolism of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses by Klebsiella pneumoniae. Participation and properties of sucrose-6-phosphate hydrolase and phospho-alpha-glucosidase · PMID 11473129 · 12 records
• Metabolism of the anti-tuberculosis drug ethionamide by mouse and human FMO1, FMO2 and FMO3 and mouse and human lung microsomes · PMID 18930751 · 6 records
• Metadynamics Simulations Meet Ligand Design for the Reversible Inhibition of Human Peroxiredoxin 5 · PMID 42540239 · 1 record
• Metal binding Asp-120 in metallo-beta-lactamase L1 from Stenotrophomonas maltophilia plays a crucial role in catalysis · PMID 14573595 · 23 records
• Metal binding stoichiometry and mechanism of metal ion modulation of the activity of porcine kidney leucine aminopeptidase · PMID 7295698 · 7 records
• Metal dependence of oxalate decarboxylase activity · PMID 19473032 · 8 records
• Metal requirements and phosphodiesterase activity of tRNase Z enzymes · PMID 18052196 · 9 records
• Metal-cation regulation of enzyme dynamics is a key factor influencing the activity of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa · PMID 30054521 · 7 records
• Metal-ion dependent catalytic properties of Sulfolobus solfataricus class ii α-mannosidase · PMID 22989181 · 20 records
• Methanogen homoaconitase catalyzes both hydrolyase reactions in coenzyme B biosynthesis · PMID 18765671 · 9 records
• Methionine Adenosyltransferase Engineering to Enable Bioorthogonal Platforms for AdoMet-Utilizing Enzymes · PMID 32091873 · 6 records
• Methionine residues lining the substrate pathway in prolyl oligopeptidase from Pleurotus eryngii play an important role in substrate recognition · PMID 29623768 · 16 records
• Methionine γ-lyase in enzyme prodrug therapy: An improvement of pharmacokinetic parameters of the enzyme · PMID 31470057 · 8 records
• Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers · PMID 7890613 · 16 records
• Methyl syringate: an efficient phenolic mediator for bacterial and fungal laccases · PMID 22995168 · 6 records
• Methylation of gibberellins by Arabidopsis GAMT1 and GAMT2 · PMID 17220201 · 4 records
• Methylcitrate cycle activation during adaptation of Fusarium solani and Fusarium verticillioides to propionyl-CoA-generating carbon sources · PMID 19661181 · 8 records
• Methylcitrate synthase from Aspergillus fumigatus. Propionyl-CoA affects polyketide synthesis, growth and morphology of conidia · PMID 16008561 · 7 records
• Methylenetetrahydrofolate dehydrogenase-cyclohydrolase from Photobacterium phosphoreum shares properties with a mammalian mitochondrial homologue · PMID 8765228 · 5 records
• Methylglyoxal detoxification by an aldo-keto reductase in the cyanobacterium Synechococcus sp. PCC 7002 · PMID 16804176 · 11 records
• Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1 · PMID 15082749 · 24 records
• Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing · PMID 21197954 · 3 records
• Microbial production of branched-chain dicarboxylate 2-methylsuccinic acid via enoate reductase-mediated bioreduction · PMID 29155059 · 4 records
• Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues · PMID 18258203 · 25 records
• Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A · PMID 12962489 · 4 records
• Mining Thermophile Genomes for New PETases with Exceptional Thermostabilities Using Sequence Similarity Networks · PMID 40069109 · 14 records
• Misfolding of galactose 1-phosphate uridylyltransferase can result in type I galactosemia · PMID 23583749 · 12 records
• Misfolding PRSS1 variant p.Ala61Val in a case of suspected intrauterine pancreatitis · PMID 39734120 · 2 records
• Mismatch-Driven CRISPR/Cas12a Biosensing of UV-Induced DNA Lesions for Environmental Solar Exposure Surveillance · PMID 41935970 · 3 records
• Mitochondrial exonuclease EXOG supports DNA integrity by the removal of single-stranded DNA flaps · PMID 40042814 · 2 records
• Mitochondrial malate dehydrogenase from the thermophilic, filamentous fungus Talaromyces emersonii · PMID 15265031 · 8 records
• Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues · PMID 24733394 · 6 records
• Mitochondrial trans-2-enoyl-CoA reductase of wax ester fermentation from Euglena gracilis defines a new family of enzymes involved in lipid synthesis · PMID 15569691 · 4 records
• Mixed disulfide formation at Cys141 leads to apparent unidirectional attenuation of Aspergillus niger NADP-glutamate dehydrogenase activity · PMID 24987966 · 10 records
• MJ0109 is an enzyme that is both an inositol monophosphatase and the 'missing' archaeal fructose-1,6-bisphosphatase · PMID 11062561 · 10 records
• MJ0917 in archaeon Methanococcus jannaschii is a novel NADP phosphatase/NAD kinase · PMID 16192277 · 5 records
• Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells · PMID 18352857 · 5 records
• Mode of action and properties of the beta-xylosidases from Talaromyces emersonii and Trichoderma reesei · PMID 16752410 · 12 records
• Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis · PMID 16363801 · 15 records
• Modification of activity and specificity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26 by engineering of its entrance tunnel · PMID 14525993 · 33 records
• Modification of auxinic phenoxyalkanoic acid herbicides by the acyl acid amido synthetase GH3.15 from Arabidopsis · PMID 30315112 · 19 records
• Modification of the peroxygenative:peroxidative activity ratio in the unspecific peroxygenase from Agrocybe aegerita by structure-guided evolution · PMID 28044007 · 6 records
• Modification of the substrate specificity of porcine pepsin for the enzymatic production of bovine hide gelatin · PMID 11106168 · 45 records
• Modifications of the Prothrombin Active Site S4 Subpocket Confer Resistance to Dabigatran · PMID 39938570 · 8 records
• Modified Deacetylcephalosporin C Synthase for the Biotransformation of Semisynthetic Cephalosporins · PMID 27084018 · 6 records
• Modified substrate specificity of L-hydroxyisocaproate dehydrogenase derived from structure-based protein engineering · PMID 9153075 · 50 records
• Modifying recombinant purple acid phosphatase using computational design · PMID 40650743 · 16 records
• Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution · PMID 12626743 · 12 records
• Modulating O2 reactivity in a fungal flavoenzyme: involvement of aryl-alcohol oxidase Phe-501 contiguous to catalytic histidine · PMID 21940622 · 8 records
• Modulating the thermostability of Endoglucanase I from Trichoderma reesei using computational approaches · PMID 25784767 · 4 records
• Modulation of acceptor specificity of Ruminococcus albus cellobiose phosphorylase through site-directed mutagenesis · PMID 23845516 · 14 records
• Modulation of activity of NADH oxidase from Thermus thermophilus through change in flexibility in the enzyme active site induced by Hofmeister series anions · PMID 14686918 · 34 records
• Modulation of allosteric regulation by E38K and G101N mutations in the potato tuber ADP-glucose pyrophosphorylase · PMID 24018661 · 8 records
• Modulation of Aminoacylation and Editing Properties of Leucyl-tRNA Synthetase by a Conserved Structural Module · PMID 25817995 · 43 records
• Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol · PMID 17029589 · 52 records
• Modulation of Fructose Transfer Process for Promoting Apparent Isomerization Activity of Amylosucrase from Bifidobacterium thermophilum · PMID 41937541 · 5 records
• Modulation of human cytidine deaminase by specific aminoacids involved in the intersubunit interactions · PMID 17640070 · 9 records
• Modulation of succinyl-CoA:3-ketoacid CoA transferase activity by a single amino acid residue in acetate:succinate CoA transferase from Trypanosoma brucei, the causative agent of African sleeping… · PMID 41556494 · 14 records
• Modulation of the interaction between aldolase and glycerol-phosphate dehydrogenase by fructose phosphates · PMID 2065091 · 5 records
• Modulation of the mobility of a key region in human galactokinase: Impacts on catalysis and stability · PMID 30253338 · 26 records
• Modulation of the substrate preference of a MYST acetyltransferase by a scaffold protein · PMID 39909374 · 40 records
• Modulation of the substrate specificity of Escherichia coli dimethylsulfoxide reductase · PMID 9492325 · 48 records
• Molecular adaptations of NADP-malic enzyme for its function in C₄ photosynthesis in grasses · PMID 31235877 · 24 records
• Molecular analysis of NAD⁺-dependent xylitol dehydrogenase from the zygomycetous fungus Rhizomucor pusillus and reversal of the coenzyme preference · PMID 25082263 · 16 records
• Molecular analysis of the gene encoding a new chitinase from the marine psychrophilic bacterium Moritella marina and biochemical characterization of the recombinant enzyme · PMID 18368288 · 6 records
• Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243 · PMID 15743957 · 4 records
• Molecular and biochemical characterisation of Mycobacterium smegmatis alcohol dehydrogenase C · PMID 11257547 · 5 records
• Molecular and biochemical characterization of 2-hydroxyisoflavanone dehydratase. Involvement of carboxylesterase-like proteins in leguminous isoflavone biosynthesis · PMID 15734910 · 6 records
• Molecular and biochemical characterization of AtPAP15, a purple acid phosphatase with phytase activity, in Arabidopsis · PMID 19633233 · 3 records
• Molecular and biochemical characterization of rat gamma-trimethylaminobutyraldehyde dehydrogenase and evidence for the involvement of human aldehyde dehydrogenase 9 in carnitine biosynthesis · PMID 10702312 · 37 records
• Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii · PMID 17846134 · 11 records
• Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola · PMID 19884377 · 9 records
• Molecular and biochemical characterization of three GH62 α-l-arabinofuranosidases from the soil deuteromycete Penicillium funiculosum · PMID 24034435 · 7 records
• Molecular and biochemical characterization of two brassinosteroid sulfotransferases from Arabidopsis, AtST4a (At2g14920) and AtST1 (At2g03760) · PMID 17039368 · 14 records
• Molecular and catalytic properties of an arginine kinase from the nematode Ascaris suum · PMID 21781373 · 8 records
• Molecular and catalytic properties of fungal extracellular cellobiose dehydrogenase produced in prokaryotic and eukaryotic expression systems · PMID 28245812 · 7 records
• Molecular and Enzymatic Features of Homoserine Dehydrogenase from Bacillus subtilis · PMID 33046675 · 2 records
• Molecular and kinetic comparison of the novel extended-spectrum beta-lactamases CTX-M-25 and CTX-M-26 · PMID 15561863 · 16 records
• Molecular and phylogenetic characterization of isopropylmalate dehydrogenase of a thermoacidophilic archaeon, Sulfolobus sp. strain 7 · PMID 9023199 · 9 records
• Molecular and physiological role of the trehalose-hydrolyzing alpha-glucosidase from Thermus thermophilus HB27 · PMID 18223075 · 11 records
• Molecular and structural characterization of agmatine coumaroyltransferase in Triticeae, the key regulator of hydroxycinnamic acid amide accumulation · PMID 34119689 · 38 records
• Molecular and structural characterization of hexameric beta-D-glucosidases in wheat and rye · PMID 16751439 · 51 records
• Molecular annotation of ketol-acid reductoisomerases from Streptomyces reveals a novel amino acid biosynthesis interlock mediated by enzyme promiscuity · PMID 25296650 · 82 records
• Molecular architecture of the glucose 1-phosphate site in ADP-glucose pyrophosphorylases · PMID 17079236 · 41 records
• Molecular architecture of TylM1 from Streptomyces fradiae: an N,N-dimethyltransferase involved in the production of dTDP-D-mycaminose · PMID 21142177 · 3 records
• Molecular architectures of benzoic acid-specific type III polyketide synthases · PMID 29199980 · 10 records
• Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase · PMID 25692488 · 59 records
• Molecular basis and biological relevance of bacterial and plant pinoresinol/lariciresinol reductase specificities · PMID 41556626 · 8 records
• Molecular basis for branched steviol glucoside biosynthesis · PMID 31182573 · 36 records
• Molecular basis for enantioselectivity in the (R)- and (S)-hydroxypropylthioethanesulfonate dehydrogenases, a unique pair of stereoselective short-chain dehydrogenases/reductases involved in… · PMID 20302306 · 29 records
• Molecular basis for enzymatic sulfite oxidation: how three conserved active site residues shape enzyme activity · PMID 19004819 · 30 records
• Molecular basis for N-terminal acetylation by the heterodimeric NatA complex · PMID 23912279 · 28 records
• Molecular basis for the isozymes of bovine glucose-6-phosphate isomerase · PMID 3369868 · 8 records
• Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase · PMID 8985174 · 27 records
• Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA · PMID 1931965 · 39 records
• Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase · PMID 27642068 · 13 records
• Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase · PMID 33773110 · 24 records
• Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana · PMID 16166087 · 40 records
• Molecular basis of exopeptidase activity in the C-terminal domain of human angiotensin I-converting enzyme: insights into the origins of its exopeptidase activity · PMID 15615692 · 16 records
• Molecular basis of formaldehyde detoxification. Characterization of two S-formylglutathione hydrolases from Escherichia coli, FrmB and YeiG · PMID 16567800 · 17 records
• Molecular basis of perhydrolase activity in serine hydrolases · PMID 15803517 · 4 records
• Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin · PMID 19702337 · 4 records
• Molecular basis of substrate recognition in D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida · PMID 16888731 · 10 records
• Molecular basis of the activity of the phytopathogen pectin methylesterase · PMID 17717531 · 6 records
• Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad · PMID 24737327 · 6 records
• Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans · PMID 19351325 · 14 records
• Molecular basis of the substrate specificity and the catalytic mechanism of citramalate synthase from Leptospira interrogans · PMID 18498255 · 42 records
• Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase · PMID 19292872 · 37 records
• Molecular characterization and expression of a novel alcohol oxidase from Aspergillus terreus MTCC6324 · PMID 24752075 · 4 records
• Molecular characterization and verification of azido-3,8-dideoxy-d-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide · PMID 29018092 · 2 records
• Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase · PMID 15561840 · 15 records
• Molecular characterization of a first human 3(alpha-->beta)-hydroxysteroid epimerase · PMID 10896656 · 5 records
• Molecular Characterization of a Mesophilic Cellobiose 2-Epimerase That Maintains a High Catalytic Efficiency at Low Temperatures · PMID 34231359 · 2 records
• Molecular characterization of a novel arylesterase from the wine-associated acetic acid bacterium Gluconobacter oxidans 621H · PMID 23003572 · 8 records
• Molecular characterization of a novel beta-glucuronidase from Scutellaria baicalensis georgi · PMID 10858442 · 4 records
• Molecular characterization of a novel thermostable mannose-6-phosphate isomerase from Thermus thermophilus · PMID 21729734 · 9 records
• Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily · PMID 18006499 · 9 records
• Molecular characterization of a thermostable L-fucose isomerase from Dictyoglomus turgidum that isomerizes L-fucose and D-arabinose · PMID 22627384 · 17 records
• Molecular characterization of human ABHD2 as TAG lipase and ester hydrolase · PMID 27247428 · 3 records
• Molecular characterization of L-amino acid oxidase from king cobra venom · PMID 17543361 · 5 records
• Molecular characterization of lysine 6-dehydrogenase from Achromobacter denitrificans · PMID 19017491 · 5 records
• Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney · PMID 11882650 · 135 records
• Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis · PMID 18815383 · 11 records
• Molecular characterization of pyridoxine 5'-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy · PMID 32788630 · 7 records
• Molecular characterization of two monkey dihydrodiol dehydrogenases · PMID 15618685 · 96 records
• Molecular cloning and baculovirus expression of the rabbit corneal aldehyde dehydrogenase (ALDH1A1) cDNA · PMID 12941160 · 8 records
• Molecular cloning and biochemical characterization of the UDP-glucose: flavonoid 3-O-glucosyltransferase from Concord grape (Vitis labrusca) · PMID 22098678 · 3 records
• Molecular cloning and biochemical characterization of three phosphoglycerate kinase isoforms from developing sunflower (Helianthus annuus L.) seeds · PMID 22552275 · 18 records
• Molecular cloning and biochemical characterization of two cinnamyl alcohol dehydrogenases from a liverwort Plagiochasma appendiculatum · PMID 23774375 · 10 records
• Molecular cloning and catalytic characterization of a recombinant tropine biosynthetic tropinone reductase from Withania coagulans leaf · PMID 23266822 · 4 records
• Molecular cloning and characterization of a broad substrate terpenoid oxidoreductase from Artemisia annua · PMID 20483909 · 2 records
• Molecular cloning and characterization of a GH10 thermophilic xylanase from hot spring and its potential application in promoting probiotic growth · PMID 41501755 · 1 record
• Molecular cloning and characterization of a M17 leucine aminopeptidase of Cryptosporidium parvum · PMID 21414242 · 5 records
• Molecular cloning and characterization of a novel metagenome-derived multicopper oxidase with alkaline laccase activity and highly soluble expression · PMID 20358193 · 6 records
• Molecular cloning and characterization of an alpha-amylase from Pichia burtonii 15-1 · PMID 18071262 · 20 records
• Molecular cloning and characterization of an NADPH quinone oxidoreductase from Kluyveromyces marxianus · PMID 14536026 · 4 records
• Molecular cloning and characterization of l-methionine γ-lyase from Streptomyces avermitilis · PMID 25817696 · 3 records
• Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family · PMID 7737980 · 30 records
• Molecular cloning and characterization of one member of 3beta-hydroxy sterol glucosyltransferase gene family in Withania somnifera · PMID 17324374 · 24 records
• Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases · PMID 15007068 · 29 records
• Molecular cloning and characterization of two thermostable carboxyl esterases from Geobacillus stearothermophilus · PMID 15033540 · 2 records
• Molecular cloning and functional analysis of nine cinnamyl alcohol dehydrogenase family members in Populus tomentosa · PMID 25096165 · 6 records
• Molecular Cloning and Functional Characterization of a Hexokinase from the Oriental River Prawn Macrobrachium nipponense in Response to Hypoxia · PMID 28608798 · 3 records
• Molecular cloning and functional characterization of multiple NADPH-cytochrome P450 reductases from Andrographis paniculata · PMID 28410952 · 6 records
• Molecular cloning and functional characterization of three distinct N-methyltransferases involved in the caffeine biosynthetic pathway in coffee plants · PMID 12746542 · 12 records
• Molecular cloning and functional characterization of three terpene synthases from unripe fruit of black pepper (Piper nigrum) · PMID 29248443 · 3 records
• Molecular cloning and functional characterization of two divergent 4-coumarate : coenzyme A ligases from Kudzu (Pueraria lobata) · PMID 24141262 · 6 records
• Molecular cloning and functional expression of codeinone reductase: the penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum · PMID 10417697 · 21 records
• Molecular cloning and functional expression of d-arabitol dehydrogenase gene from Gluconobacter oxydans in Escherichia coli · PMID 16165327 · 8 records
• Molecular cloning and heterologous expression of progesterone 5beta-reductase from Digitalis lanata Ehrh · PMID 16386278 · 5 records
• Molecular cloning and mutational analysis of the ddsA gene encoding decaprenyl diphosphate synthase from Gluconobacter suboxydans · PMID 9692900 · 19 records
• Molecular cloning and oxidative modification of human lens ALDH1A1: implication in impaired detoxification of lipid aldehydes · PMID 19296407 · 7 records
• Molecular cloning of a bifunctional beta-xylosidase/alpha-L-arabinosidase from alfalfa roots: heterologous expression in Medicago truncatula and substrate specificity of the purified enzyme · PMID 17615411 · 3 records
• Molecular cloning of a novel type of rat cytoplasmic 17beta-hydroxysteroid dehydrogenase distinct from the type 5 isozyme · PMID 16788056 · 96 records
• Molecular cloning of the DNA and expression and characterization of rat testes fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase · PMID 1651918 · 3 records
• Molecular cloning, characterization and in silico analysis of a thermostable β-glucosidase enzyme from Putranjiva roxburghii with a significant activity for cellobiose · PMID 28500928 · 6 records
• Molecular cloning, characterization, and potential roles of cytosolic and mitochondrial aldehyde dehydrogenases in ethanol metabolism in Saccharomyces cerevisiae · PMID 9473035 · 18 records
• Molecular cloning, chromosomal assignment and tissue-specific expression of a murine alpha(1,2)fucosyltransferase expressed in thymic and epididymal epithelial cells · PMID 9355741 · 11 records
• Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a… · PMID 9576847 · 16 records
• Molecular cloning, expression and characterization of pyridoxamine-pyruvate aminotransferase · PMID 16545075 · 6 records
• Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.) · PMID 15381407 · 4 records
• Molecular cloning, expression, and properties of an unusual aldo-keto reductase family enzyme, pyridoxal 4-dehydrogenase, that catalyzes irreversible oxidation of pyridoxal · PMID 15226311 · 7 records
• Molecular cloning, overexpression and characterization of a novel feruloyl esterase from a soil metagenomic library · PMID 21757926 · 6 records
• Molecular cloning, overexpression, purification, and characterization of an aerobic FMN-dependent azoreductase from Enterococcus faecalis · PMID 15003265 · 2 records
• Molecular cloning, purification, and biochemical characterization of a novel pyrethroid-hydrolyzing esterase from Klebsiella sp. strain ZD112 · PMID 16448191 · 12 records
• Molecular cloning, sequencing and expression of a cDNA encoding a human liver NAD-dependent alpha-glycerol-3-phosphate dehydrogenase · PMID 7772607 · 3 records
• Molecular cloning, substrate specificity of the functionally expressed dihydroflavonol 4-reductases from Malus domestica and Pyrus communis cultivars and the consequences for flavonoid metabolism · PMID 12667486 · 5 records
• Molecular conversion of NAD kinase to NADH kinase through single amino acid residue substitution · PMID 15855156 · 22 records
• Molecular Determinants of N-Acetylglucosamine Recognition and Turnover by N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside Deacetylase (MshB) · PMID 26024468 · 5 records
• Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channels · PMID 17675410 · 10 records
• Molecular Dissection of Escherichia coli CpdB: Roles of the N Domain in Catalysis and Phosphate Inhibition, and of the C Domain in Substrate Specificity and Adenosine Inhibition · PMID 33671286 · 16 records
• Molecular diversity of sterol 14alpha-demethylase substrates in plants, fungi and humans · PMID 9559662 · 9 records
• Molecular dynamics simulations and structure-guided mutagenesis provide insight into the architecture of the catalytic core of the ectoine hydroxylase · PMID 24184278 · 14 records
• Molecular Engineering L-Aspartate-Alpha-Decarboxylase to Enhance Catalytic Stability and Performance · PMID 39460447 · 3 records
• Molecular Engineering of Nicotinamide Riboside Kinase and Process Optimization for Efficient Nicotinamide Mononucleotide Production · PMID 42279625 · 4 records
• Molecular evolution and characterization of fungal indoleamine 2,3-dioxygenases · PMID 21170645 · 8 records
• Molecular evolution by change of function. Alkaloid-specific homospermidine synthase retained all properties of deoxyhypusine synthase except binding the eIF5A precursor protein · PMID 12562768 · 22 records
• Molecular identification of a functional homologue of the mammalian fatty acid amide hydrolase in Arabidopsis thaliana · PMID 12824167 · 5 records
• Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1) · PMID 20097752 · 21 records
• Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency · PMID 12547821 · 11 records
• Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine · PMID 22241472 · 6 records
• Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the alpha-D-phosphohexomutase family · PMID 17804405 · 11 records
• Molecular identification of omega-amidase, the enzyme that is functionally coupled with glutamine transaminases, as the putative tumor suppressor Nit2 · PMID 19596042 · 8 records
• Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation · PMID 19155213 · 8 records
• Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase · PMID 17197414 · 5 records
• Molecular Interplay between the Dimer Interface and the Substrate-Binding Site of Human Peptidylarginine Deiminase 4 · PMID 28209966 · 30 records
• Molecular interpretation of inhibition by excess substrate in flavocytochrome b2: a study with wild-type and Y143F mutant enzymes · PMID 9188712 · 34 records
• Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation · PMID 15576032 · 10 records
• Molecular mechanism of ADP-ribose hydrolysis by human NUDT5 from structural and kinetic studies · PMID 18462755 · 22 records
• Molecular mechanism of N-terminal acetylation by the ternary NatC complex · PMID 34019809 · 14 records
• Molecular mechanism of the enterococcal aminoglycoside 6'-N-acetyltransferase': role of GNAT-conserved residues in the chemistry of antibiotic inactivation · PMID 14717599 · 39 records
• Molecular mechanism of the Thermus thermophilus ADP-ribose pyrophosphatase from mutational and kinetic studies · PMID 15981998 · 35 records
• Molecular Mechanisms of AhpC in Resistance to Oxidative Stress in Burkholderia thailandensis · PMID 31338075 · 12 records
• Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations identified in tumors: The role of size and hydrophobicity at residue 132 on catalytic efficiency · PMID 28330869 · 115 records
• Molecular mechanisms of substrate recognition and specificity of botulinum neurotoxin serotype F · PMID 21029044 · 21 records
• Molecular Mechanisms Underlying the Loop-Closing Dynamics of β-1,4 Galactosyltransferase 1 · PMID 39737871 · 11 records
• Molecular modeling and site-directed mutagenesis reveal the benzylisoquinoline binding site of the short-chain dehydrogenase/reductase salutaridine reductase · PMID 17337529 · 18 records
• Molecular properties and enhancement of thermostability by random mutagenesis of glutamate dehydrogenase from Bacillus subtilis · PMID 16244435 · 11 records
• Molecular recognition of tryptophan tRNA by tryptophanyl-tRNA synthetase from Aeropyrum pernix K1 · PMID 19179361 · 23 records
• Molecular, kinetic and thermodynamic characterization of Mycobacterium tuberculosis orotate phosphoribosyltransferase · PMID 22075667 · 6 records
• Molybdopterin dinucleotide biosynthesis in Escherichia coli: identification of amino acid residues of molybdopterin dinucleotide transferases that determine specificity for binding of guanine or… · PMID 21081498 · 11 records
• MomL, a novel marine-derived N-acyl homoserine lactonase from Muricauda olearia · PMID 25398866 · 8 records
• Monomeric NADH-Oxidizing Methylenetetrahydrofolate Reductases from Mycobacterium smegmatis Lack Flavin Coenzyme · PMID 32253341 · 4 records
• Monooxygenase Activity of Indoleamine 2,3-Dioxygenase · PMID 41640298 · 1 record
• Monooxygenase Substrates Mimic Flavin to Catalyze Cofactorless Oxygenations · PMID 27307041 · 4 records
• Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint · PMID 13679086 · 6 records
• Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate · PMID 19487664 · 4 records
• Moonlighting glutamate formiminotransferases can functionally replace 5-formyltetrahydrofolate cycloligase · PMID 20952389 · 15 records
• Motif V is an allosteric couple between the SARS-CoV-2 nsp13 nucleotide triphosphatase and helicase active sites · PMID 41581884 · 12 records
• Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate… · PMID 17442338 · 6 records
• Mouse aminoacylase 3: a metalloenzyme activated by cobalt and nickel · PMID 19362172 · 44 records
• Mouse glutamate carboxypeptidase II (GCPII) has a similar enzyme activity and inhibition profile but a different tissue distribution to human GCPII · PMID 28904865 · 4 records
• Mouse liver dihydrodiol dehydrogenases. Identity of the predominant and a minor form with 17 beta-hydroxysteroid dehydrogenase and aldehyde reductase · PMID 3276326 · 42 records
• Mouse RS21-C6 is a mammalian 2'-deoxycytidine 5'-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine · PMID 19220460 · 13 records
• MptpB, a virulence factor from Mycobacterium tuberculosis, exhibits triple-specificity phosphatase activity · PMID 17584180 · 19 records
• Multi-Enzymatic Cascade Synthesis of Oligosaccharide Haptens from Streptococcus suis Serotype 2 and 1/2 Capsular Polysaccharides and Antigenicity Evaluation · PMID 42063853 · 6 records
• Multi-Functional Alginate Lyase AlgVR7 from Vibrio rumoiensis: Structural Insights and Catalytic Mechanisms · PMID 40137310 · 3 records
• Multi-site substrate binding and interplay in barley alpha-amylase 1 · PMID 18588886 · 8 records
• Multiple amino acid substitutions significantly improve the thermostability of feruloyl esterase A from Aspergillus niger · PMID 22613889 · 4 records
• Multiple determinants for the high substrate specificity of an angiotensin II-forming chymase from the human heart · PMID 1918036 · 17 records
• Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools · PMID 15850400 · 14 records
• Multiple forms of mutarotases from the kidney, liver, and small intestine of rats: purification, properties, subcellular localization and developmental changes · PMID 6630166 · 44 records
• Multiple forms of the asclepains. Cysteinyl proteases from milkweed · PMID 6988008 · 10 records
• Multiple forms of xylose reductase in Candida intermedia: comparison of their functional properties using quantitative structure-activity relationships, steady-state kinetic analysis, and pH studies · PMID 14690376 · 49 records
• Multiple molecular forms of ATP:hexose 6-phosphotransferase from rat liver · PMID 5871820 · 10 records
• Multiple Reaction Products from the Hydrolysis of Chiral and Prochiral Organophosphate Substrates by the Phosphotriesterase from Sphingobium sp. TCM1 · PMID 29513982 · 14 records
• Mushroom hunting by using bioinformatics: application of a predictive framework facilitates the selective identification of sesquiterpene synthases in basidiomycota · PMID 24166732 · 3 records
• Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase · PMID 7761851 · 8 records
• Mutagenesis and mechanistic study of a glycoside hydrolase family 54 alpha-L-arabinofuranosidase from Trichoderma koningii · PMID 17002602 · 19 records
• Mutagenesis at two distinct phosphate-binding sites unravels their differential roles in regulation of Rubisco activation and catalysis · PMID 15937184 · 13 records
• Mutagenesis evidence that the partial reactions of firefly bioluminescence are catalyzed by different conformations of the luciferase C-terminal domain · PMID 15683224 · 22 records
• Mutagenesis of a conserved glutamate reveals the contribution of electrostatic energy to adenosylcobalamin co-C bond homolysis in ornithine 4,5-aminomutase and methylmalonyl-CoA mutase · PMID 23311430 · 7 records
• Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylase · PMID 23368961 · 77 records
• Mutagenesis of Ala290, which modulates substrate subsite affinity at the catalytic interface of dimeric ThMA · PMID 15975859 · 12 records
• Mutagenesis of an Asn156 Residue in a Surface Region of S-Selective Hydroxynitrile Lyase from Baliospermum montanum Enhances Catalytic Efficiency and Enantioselectivity · PMID 26109164 · 6 records
• Mutagenesis of catalytically important residues of cupin type phosphoglucose isomerase from Archaeoglobus fulgidus · PMID 16336264 · 12 records
• Mutagenesis of cysteine 280 of the reverse transcriptase of human immunodeficiency virus type-1: the effects on the ribonuclease H activity · PMID 12614605 · 7 records
• Mutagenesis of Glycine 179 modulates both catalytic efficiency and reduced pyridine nucleotide specificity in cytochrome b5 reductase · PMID 16216070 · 19 records
• Mutagenesis of histidinol dehydrogenase reveals roles for conserved histidine residues · PMID 10353848 · 22 records
• Mutagenesis of Key Residues in the Binding Center of l-Aspartate-b-Semialdehyde Dehydrogenase from Escherichia coli Enhances Utilization of the Cofactor NAD(H) · PMID 26662025 · 6 records
• Mutagenesis of putative catalytic and regulatory residues of Streptomyces chromofuscus phospholipase D differentially modifies phosphatase and phosphodiesterase activities · PMID 14557260 · 13 records
• Mutagenesis of residue 157 in the active site of human glyoxalase I · PMID 9359858 · 7 records
• Mutagenesis of the phosphate-binding pocket of KDPG aldolase enhances selectivity for hydrophobic substrates · PMID 17962400 · 19 records
• Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus · PMID 18375951 · 11 records
• Mutagenesis studies toward understanding allostery in thrombin · PMID 19640005 · 10 records
• Mutagenic and chemical analyses provide new insight into enzyme activation and mechanism of the type 2 iron-sulfur l-serine dehydratase from Legionella pneumophila · PMID 26971469 · 8 records
• Mutagenic and kinetic support for an allosteric site in arginase from the extreme thermophile Bacillus caldovelox, which allows activation by arginine · PMID 25447142 · 7 records
• Mutagenic investigation of conserved functional amino acids in Escherichia coli L-aspartase · PMID 8119980 · 5 records
• Mutant IDH1 enhances the production of 2-hydroxyglutarate due to its kinetic mechanism · PMID 23731180 · 28 records
• Mutant N143P reveals how Na+ activates thrombin · PMID 19846563 · 23 records
• Mutant rat trypsin selectively cleaves tyrosyl peptide bonds · PMID 15003560 · 23 records
• Mutated forms of phosphoglycerate mutase in yeast affect reversal of metabolic flux. Effect of reversible and irreversible function of an enzyme on pathway reversal · PMID 2844813 · 4 records
• Mutation network-based understanding of pleiotropic and epistatic mutational behavior of Enterococcus faecalis FMN-dependent azoreductase · PMID 29214224 · 12 records
• Mutation of active site residues of insulin-degrading enzyme alters allosteric interactions · PMID 15749695 · 7 records
• Mutation of Arg-115 of human class III alcohol dehydrogenase: a binding site required for formaldehyde dehydrogenase activity and fatty acid activation · PMID 8460164 · 13 records
• Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase I · PMID 15736931 · 8 records
• Mutation of asparagine 229 to aspartate in thymidylate synthase converts the enzyme to a deoxycytidylate methylase · PMID 1606134 · 6 records
• Mutation of essential catalytic residues in pig citrate synthase · PMID 1702991 · 9 records
• Mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease · PMID 20371333 · 7 records
• Mutation of Lys242 allows Delta3-Delta2-enoyl-CoA isomerase to acquire enoyl-CoA hydratase activity · PMID 16952422 · 13 records
• Mutation of regulatory serines of rat tyrosine hydroxylase to glutamate: effects on enzyme stability and activity · PMID 15639226 · 43 records
• Mutation of surface cysteine 374 to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines · PMID 15848762 · 10 records
• Mutation of Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase at Trp-110 affects stereoselectivity of aromatic ketone reduction · PMID 24984815 · 14 records
• Mutation to phenylalanine of tyrosine 371 in tyrosine hydroxylase increases the affinity for phenylalanine · PMID 9819237 · 14 records
• Mutational analysis defines the roles of conserved amino acid residues in the predicted catalytic pocket of the rRNA:m6A methyltransferase ErmC' · PMID 12946350 · 16 records
• Mutational analysis of 4-coumarate:CoA ligase identifies functionally important amino acids and verifies its close relationship to other adenylate-forming enzymes · PMID 10664468 · 13 records
• Mutational analysis of a feruloyl esterase from Aspergillus awamori involved in substrate discrimination and pH dependence · PMID 15716038 · 10 records
• Mutational analysis of a helicase motif-based RNA 5'-triphosphatase/NTPase from bamboo mosaic virus · PMID 17585982 · 12 records
• Mutational analysis of a key residue in the substrate specificity of a cephalosporin acylase · PMID 15174165 · 31 records
• Mutational analysis of a nucleosidase involved in quorum-sensing autoinducer-2 biosynthesis · PMID 16101288 · 24 records
• Mutational analysis of allylic substrate binding site of Micrococcus luteus B-P 26 undecaprenyl diphosphate synthase · PMID 12680756 · 26 records
• Mutational analysis of Asp51 of Anabaena azollae glutamine synthetase. D51E mutation confers resistance to the active site inhibitors L-methionine-DL-sulfoximine and phosphinothricin · PMID 10583418 · 20 records
• Mutational analysis of catecholamine binding in tyrosine hydroxylase · PMID 21235236 · 24 records
• Mutational analysis of cysteine 328 and cysteine 368 at the interface of Plasmodium falciparum adenylosuccinate synthetase · PMID 22289630 · 18 records
• Mutational analysis of divalent metal ion binding in the active site of class II α-mannosidase from Sulfolobus solfataricus · PMID 25751413 · 22 records
• Mutational analysis of domain II of flavonol 3-sulfotransferase · PMID 9288931 · 37 records
• Mutational analysis of duck delta 2 crystallin and the structure of an inactive mutant with bound substrate provide insight into the enzymatic mechanism of argininosuccinate lyase · PMID 11698398 · 8 records
• Mutational analysis of mammalian poly(A) polymerase identifies a region for primer binding and catalytic domain, homologous to the family X polymerases, and to other nucleotidyltransferases · PMID 8665867 · 11 records
• Mutational analysis of N-glycosylation recognition sites on the biochemical properties of Aspergillus kawachii alpha-L-arabinofuranosidase 54 · PMID 16784813 · 4 records
• Mutational analysis of parasite trypanothione reductase: acquisition of glutathione reductase activity in a triple mutant · PMID 2007114 · 16 records
• Mutational analysis of peptidyl carrier protein and acyl carrier protein synthase unveils residues involved in protein-protein recognition · PMID 15248752 · 19 records
• Mutational analysis of residues in the nucleotide binding domain of human terminal deoxynucleotidyl transferase · PMID 8163485 · 18 records
• Mutational analysis of sites in sepiapterin reductase phosphorylated by Ca2+/calmodulin-dependent protein kinase II · PMID 11825621 · 8 records
• Mutational analysis of the active site flap (20s loop) of mandelate racemase · PMID 18092808 · 60 records
• Mutational analysis of the active site residues of a D: -psicose 3-epimerase from Agrobacterium tumefaciens · PMID 19859667 · 10 records
• Mutational analysis of the active-site residues crucial for catalytic activity of adenosine kinase from Leishmania donovani · PMID 15606359 · 11 records
• Mutational analysis of the catalytic residues lysine 230 and tyrosine 160 in the NADP(+)-dependent isocitrate dehydrogenase from Escherichia coli · PMID 7819221 · 11 records
• Mutational analysis of the conserved cationic residues of Bacillus stearothermophilus 6-phosphoglucose isomerase · PMID 9826199 · 11 records
• Mutational analysis of the substrate binding/catalytic domains of human M form and P form phenol sulfotransferases · PMID 10788459 · 30 records
• Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum · PMID 15139852 · 17 records
• Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-beta-lactamase · PMID 11964169 · 86 records
• Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila · PMID 18498253 · 55 records
• Mutational analysis of UMP kinase from Escherichia coli · PMID 9457846 · 28 records
• Mutational analysis suggests the same design for editing activities of two tRNA synthetases · PMID 8611551 · 15 records
• Mutational and Functional Analyses of Substrate Binding and Catalysis of the Listeria monocytogenes EutT ATP:Co(I)rrinoid Adenosyltransferase · PMID 32125848 · 10 records
• Mutational and structural analysis of aglycone specificity in maize and sorghum beta-glucosidases · PMID 12684498 · 59 records
• Mutational and structural analysis of cobalt-containing nitrile hydratase on substrate and metal binding · PMID 14717710 · 14 records
• Mutational and Structural Analysis of Conserved Residues in Ribose-5-Phosphate Isomerase B from Leishmania donovani: Role in Substrate Recognition and Conformational Stability · PMID 26953696 · 5 records
• Mutational, kinetic, and NMR studies of the mechanism of E. coli GDP-mannose mannosyl hydrolase, an unusual Nudix enzyme · PMID 12196023 · 22 records
• Mutational, structural, and kinetic evidence for a dissociative mechanism in the GDP-mannose mannosyl hydrolase reaction · PMID 15966723 · 19 records
• Mutational, structural, and kinetic studies of the ATP-binding site of Methanobacterium thermoautotrophicum nicotinamide mononucleotide adenylyltransferase · PMID 12810729 · 14 records
• Mutations affecting the internal equilibrium of the reaction catalyzed by 6-aminohexanoate-dimer hydrolase · PMID 27529542 · 8 records
• Mutations at the S1 sites of methionine aminopeptidases from Escherichia coli and Homo sapiens reveal the residues critical for substrate specificity · PMID 14976199 · 5 records
• Mutations in the small subunit of ribulosebisphosphate carboxylase affect subunit binding and catalysis · PMID 1911767 · 18 records
• Mutations in two specific residues of testicular angiotensin-converting enzyme change its catalytic properties · PMID 7902354 · 7 records
• Mutations on aromatic residues of the active site to alter selectivity of the Sulfolobus solfataricus maltooligosyltrehalose synthase · PMID 19127729 · 19 records
• Mutually exclusive pathways for biosynthesis of polyamine homospermidine dependent on putrescine or agmatine · PMID 42665092 · 12 records
• MxiN Differentially Regulates Monomeric and Oligomeric Species of the Shigella Type Three Secretion System ATPase Spa47 · PMID 29595954 · 6 records
• Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery · PMID 25631047 · 23 records
• Mycobacterium tuberculosis FprA, a novel bacterial NADPH-ferredoxin reductase · PMID 12071965 · 12 records
• Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action · PMID 19307712 · 4 records
• myo-Inositol-1-Phosphatase from the Pollen of Lilium longiflorum Thunb · PMID 16662572 · 9 records
• Myrosinases from root and leaves of Arabidopsis thaliana have different catalytic properties · PMID 19703694 · 6 records
• N- and S-oxygenation activity of truncated human flavin-containing monooxygenase 3 and its common polymorphic variants · PMID 33152328 · 40 records
• N-acetyl lysyl-tRNA synthetases evolved by a CcdB-based selection possess N-acetyl lysine specificity in vitro and in vivo · PMID 22289181 · 3 records
• N-Acetyl-D-glucosamine-6-phosphate deacetylase: substrate activation via a single divalent metal ion · PMID 17567047 · 30 records
• N-acetyl-L-glutamate kinase (NAGK) from oxygenic phototrophs: P(II) signal transduction across domains of life reveals novel insights in NAGK control · PMID 19409905 · 45 records
• N-acetylamino acid utilization by kidney aminoacylase-1 · PMID 18222180 · 30 records
• N-acetylgalactosamine kinase: a naturally promiscuous small molecule kinase · PMID 21984386 · 44 records
• N-Carbamoyl-β-alanine amidohydrolase from Agrobacterium tumefaciens C58: a promiscuous enzyme for the production of amino acids · PMID 21515096 · 17 records
• N-glucosylation of cytokinins by glycosyltransferases of Arabidopsis thaliana · PMID 15342621 · 10 records
• N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding · PMID 14691230 · 40 records
• N-Terminal methionine processing by the zinc-activated Plasmodium falciparum methionine aminopeptidase 1b · PMID 27023914 · 6 records
• N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase from Streptococcus lactis. Purification and partial characterization · PMID 2498334 · 4 records
• N5-CAIR mutase: role of a CO2 binding site and substrate movement in catalysis · PMID 17298082 · 5 records
• Na+ site in blood coagulation factor IXa: effect on catalysis and factor VIIIa binding · PMID 15913649 · 16 records
• NAD biosynthesis: identification of the tryptophan to quinolinate pathway in bacteria · PMID 14700627 · 7 records
• NAD(+)-dependent D-2-hydroxyisocaproate dehydrogenase of Lactobacillus delbrueckii subsp. bulgaricus. Gene cloning and enzyme characterization · PMID 7925358 · 7 records
• NAD(P)H-dependent aldose reductase from the xylose-assimilating yeast Candida tenuis. Isolation, characterization and biochemical properties of the enzyme · PMID 9307017 · 11 records
• NAD(P)H:menadione oxidoreductase of the amitochondriate eukaryote Giardia lamblia: a simpler homologue of the vertebrate enzyme · PMID 11238963 · 8 records
• NADH/NADPH bi-cofactor-utilizing and thermoactive ketol-acid reductoisomerase from Sulfolobus acidocaldarius · PMID 29739976 · 14 records
• NADP(+)-dependent D-xylose dehydrogenase from pig liver. Purification and properties · PMID 2327952 · 13 records
• NADP(H) allosterically regulates the interaction between ferredoxin and ferredoxin-NADP⁺ reductase · PMID 31665566 · 19 records
• NADP(H) phosphatase activities of archaeal inositol monophosphatase and eubacterial 3'-phosphoadenosine 5'-phosphate phosphatase · PMID 17616624 · 13 records
• NADP+-dependent farnesol dehydrogenase, a corpora allata enzyme involved in juvenile hormone synthesis · PMID 19940247 · 7 records
• NADP-dependent alcohol dehydrogenases in bacteria and yeast: purification and partial characterization of the enzymes from Acinetobacter calcoaceticus and Saccharomyces cerevisiae · PMID 8162187 · 41 records
• NADP-Dependent Aldehyde Dehydrogenase from Archaeon Pyrobaculum sp.1860: Structural and Functional Features · PMID 27956891 · 4 records
• NADPH-dependent reductases involved in the detoxification of reactive carbonyls in plants · PMID 21169366 · 38 records
• Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies · PMID 39655780 · 4 records
• Nanomachine Networks: Functional All-Enzyme Hydrogels from Photochemical Cross-Linking of Glucose Oxidase · PMID 39847607 · 2 records
• Naphthyl Thio- and Carba-xylopyranosides for Exploration of the Active Site of β-1,4-Galactosyltransferase 7 (β4GalT7) · PMID 29024190 · 5 records
• Nardilysin cleaves peptides at monobasic sites · PMID 12590613 · 19 records
• Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase · PMID 15461450 · 5 records
• Naturally occurring Class A ss-lactamases from the Burkholderia cepacia complex · PMID 19075063 · 12 records
• Naturally occurring mutations in human mitochondrial pre-tRNASer(UCN) can affect the transfer ribonuclease Z cleavage site, processing kinetics, and substrate secondary structure · PMID 16361254 · 10 records
• NCY-1 β-Lactamase Activity Correlates With Antimicrobial Susceptibility of a Clinical Strain of Nocardia cyriacigeorgica · PMID 41860015 · 5 records
• Negative regulation of the yeast ABC transporter Ycf1p by phosphorylation within its N-terminal extension · PMID 18667437 · 4 records
• Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates · PMID 10873836 · 20 records
• Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine · PMID 23754471 · 8 records
• Network reorganization of a cold-adapted β-glucosidase couples conformational flexibility to catalytic efficiency under low-temperature conditions · PMID 42577411 · 1 record
• New dye-decolorizing peroxidases from Bacillus subtilis and Pseudomonas putida MET94: towards biotechnological applications · PMID 23820555 · 15 records
• New fluorogenic probes for neutral and alkaline ceramidases · PMID 30926626 · 11 records
• New insights from the structure-function analysis of the catalytic region of human platelet phosphodiesterase 3A: a role for the unique 44-amino acid insert · PMID 16873361 · 14 records
• New insights into the alternative D-glucarate degradation pathway · PMID 18364348 · 14 records
• New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C · PMID 26055718 · 8 records
• New Insights into the Determinants of Specificity in Human Type I Arginase: Generation of a Mutant That Is Only Active with Agmatine as Substrate · PMID 35742891 · 21 records
• New insights into the mechanism of nucleoside hydrolases from the crystal structure of the Escherichia coli YbeK protein bound to the reaction product · PMID 16411753 · 6 records
• New insights into the mechanism of substrates trafficking in Glyoxylate/Hydroxypyruvate reductases · PMID 26865263 · 12 records
• New insights into the substrate specificity of macrophage elastase MMP-12 · PMID 26760307 · 142 records
• New insights into two yeast BDHs from the PDH subfamily as aldehyde reductases in context of detoxification of lignocellulosic aldehyde inhibitors · PMID 32556414 · 8 records
• New pieces to the carbon metabolism puzzle of Nitrosomonas europaea: Kinetic characterization of glyceraldehyde-3 phosphate and succinate semialdehyde dehydrogenases · PMID 30690134 · 13 records
• New role for leucyl aminopeptidase in glutathione turnover · PMID 14583094 · 12 records
• New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1 · PMID 33475202 · 21 records
• Ngt-1: A glycosyltransferase that confers resistance to three distinct antibiotic classes · PMID 42031167 · 4 records
• Nickel(II) chelatase variants directly evolved from murine ferrochelatase: porphyrin distortion and kinetic mechanism · PMID 21222436 · 16 records
• Nicotiana benthamiana cathepsin B displays distinct enzymatic features which differ from its human relative and aleurain-like protease · PMID 26166069 · 7 records
• Nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei. The effects of nicotinamide mononucleotide concentration and pH on dinucleotide synthesis · PMID 13684981 · 17 records
• Nicotinamide riboside kinase structures reveal new pathways to NAD+ · PMID 17914902 · 12 records
• Nicotinoprotein (NADH-containing) alcohol dehydrogenase from Rhodococcus erythropolis DSM 1069: an efficient catalyst for coenzyme-independent oxidation of a broad spectrum of alcohols and the… · PMID 10784035 · 50 records
• Nitric-oxide dioxygenase activity and function of flavohemoglobins. sensitivity to nitric oxide and carbon monoxide inhibition · PMID 10922365 · 11 records
• Nitrilase superfamily aryl acylamidase from the halotolerant mangrove Streptomyces sp. 211726 · PMID 24752846 · 5 records
• NMR structure and functional characterization of a human cancer-related nucleoside triphosphatase · PMID 17291528 · 7 records
• NMR study of manganese(II) binding by a new versatile peroxidase from the white-rot fungus Pleurotus eryngii · PMID 12884090 · 8 records
• NMR-based model reveals the structural determinants of mammalian arylamine N-acetyltransferase substrate specificity · PMID 16959263 · 6 records
• Non-active site mutation (Q123A) in New Delhi metallo-β-lactamase (NDM-1) enhanced its enzyme activity · PMID 29454953 · 14 records
• Non-natural cinnamic acid derivatives as substrates of cinnamate 4-hydroxylase · PMID 17141284 · 8 records
• Non-photosynthetic 'malic enzyme' from maize: a constituvely expressed enzyme that responds to plant defence inducers · PMID 11352460 · 4 records
• Non-stereoselective decomposition of (±)-S-alk(en)yl-l-cysteine sulfoxides to antibacterial thiosulfinates catalyzed by C115H mutant methionine γ-lyase from Citrobacter freundii · PMID 29803632 · 6 records
• Noncatalytic chalcone isomerase-fold proteins in Humulus lupulus are auxiliary components in prenylated flavonoid biosynthesis · PMID 29760092 · 8 records
• Nonidentity of the cDNA sequence of human breast cancer cell malic enzyme to that from the normal human cell · PMID 8804575 · 12 records
• Novel aldoxime dehydratase involved in carbon-nitrogen triple bond synthesis of Pseudomonas chlororaphis B23. Sequencing, gene expression, purification, and characterization · PMID 12773527 · 3 records
• Novel aminoglycoside 2''-phosphotransferase identified in a gram-negative pathogen · PMID 23129050 · 24 records
• Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates · PMID 21128666 · 14 records
• Novel assays to assess the prevalence and neutralizing potential of anti-IdeS antibodies in healthy humans · PMID 41737221 · 1 record
• Novel biosensors based on optimized glycine oxidase · PMID 24925096 · 37 records
• Novel CAD-like enzymes from Escherichia coli K-12 as additional tools in chemical production · PMID 23093176 · 29 records
• Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime · PMID 18955524 · 5 records
• Novel cholesterol esterase secreted by Streptomyces persists during aqueous long-term storage · PMID 16503286 · 6 records
• Novel deoxynucleoside-phosphorylating enzymes in mycoplasmas: evidence for efficient utilization of deoxynucleosides · PMID 11737647 · 7 records
• Novel family of cholesterol esterases produced by actinomycetes bacteria · PMID 17161031 · 12 records
• Novel glutaminase-free l-asparaginase from Leuconostoc mesenteroides BN1: biochemical properties, molecular dynamics, and anticancer activity · PMID 42770085 · 3 records
• Novel haloperoxidase from the agaric basidiomycete Agrocybe aegerita oxidizes aryl alcohols and aldehydes · PMID 15294788 · 5 records
• Novel heme-containing lyase, phenylacetaldoxime dehydratase from Bacillus sp. strain OxB-1: purification, characterization, and molecular cloning of the gene · PMID 10651646 · 13 records
• Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins · PMID 12071861 · 9 records
• Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism · PMID 18042490 · 3 records
• Novel modified version of nonphosphorylated sugar metabolism--an alternative L-rhamnose pathway of Sphingomonas sp · PMID 19187228 · 6 records
• Novel Nucleoside Diphosphatase Contributes to Staphylococcus aureus Virulence · PMID 27422825 · 5 records
• Novel pH-Stable Glycoside Hydrolase Family 3 β-Xylosidase from Talaromyces amestolkiae: an Enzyme Displaying Regioselective Transxylosylation · PMID 26150469 · 9 records
• Novel polyphenol oxidase mined from a metagenome expression library of bovine rumen: biochemical properties, structural analysis, and phylogenetic relationships · PMID 16740638 · 7 records
• Novel product specificity toward erlose and panose exhibited by multisite engineered mutants of amylosucrase · PMID 28019698 · 3 records
• Novel substrate specificities of two lacto-N-biosidases towards β-linked galacto-N-biose-containing oligosaccharides of globo H, Gb5, and GA1 · PMID 25839135 · 6 records
• Novel substrate specificity of a membrane-bound beta-glycosidase from the hyperthermophilic archaeon Pyrococcus horikoshii · PMID 10675537 · 15 records
• Novel substrates of a ribose-5-phosphate isomerase from Clostridium thermocellum · PMID 18984017 · 12 records
• Novel type II and monomeric NAD+ specific isocitrate dehydrogenases: phylogenetic affinity, enzymatic characterization, and evolutionary implication · PMID 25775177 · 12 records
• Novel type of ADP-forming acetyl coenzyme A synthetase in hyperthermophilic archaea: heterologous expression and characterization of isoenzymes from the sulfate reducer Archaeoglobus fulgidus and… · PMID 11790732 · 16 records
• Novel xylose dehydrogenase in the halophilic archaeon Haloarcula marismortui · PMID 15342590 · 7 records
• Novel, highly specific N-demethylases enable bacteria to live on caffeine and related purine alkaloids · PMID 22328667 · 8 records
• Nucleophilic Water Capture or Proton Loss: Single Amino Acid Switch Converts δ-Cadinene Synthase into Germacradien-4-ol Synthase · PMID 29115742 · 8 records
• Nucleoside ester prodrug substrate specificity of liver carboxylesterase · PMID 16223870 · 38 records
• Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase · PMID 33089641 · 6 records
• Nucleoside triphosphate mimicry: a sugar triazolyl nucleoside as an ATP-competitive inhibitor of B. anthracis pantothenate kinase · PMID 19763307 · 8 records
• Nucleotide binding as an allosteric regulatory mechanism for Akkermansia muciniphila β-N-acetylhexosaminidase Am2136 · PMID 36394293 · 40 records
• Nucleotide pyrophosphatase/phosphodiesterase 1 exerts a negative effect on starch accumulation and growth in rice seedlings under high temperature and CO2 concentration conditions · PMID 24092883 · 31 records
• Nucleotide recognition in the ATP-grasp protein carbamoyl phosphate synthetase · PMID 14718657 · 39 records
• Nucleotide sequence variation does not relate to differences in kinetic properties of neutral trehalase from the insect pathogenic fungus Metarhizium anisopliae · PMID 15170238 · 6 records
• Nucleotide specificity of HIV-1 reverse transcriptases with amino acid substitutions affecting Ala-114 · PMID 15548134 · 43 records
• Nucleotide specificity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase Kinetics, fluorescence spectroscopy, and molecular simulation studies · PMID 16330239 · 14 records
• Nucleotide triphosphate promiscuity in Mycobacterium tuberculosis dethiobiotin synthetase · PMID 25801336 · 28 records
• NUDIX hydrolases with inorganic polyphosphate exo- and endopolyphosphatase activities in the glycosome, cytosol and nucleus of Trypanosoma brucei · PMID 31043451 · 6 records
• NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest · PMID 20385596 · 7 records
• Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform · PMID 29378847 · 19 records
• NUDT5 hydrolyzes oxidized deoxyribonucleoside diphosphates with broad substrate specificity · PMID 19699693 · 6 records
• O-Methylation of benzaldehyde derivatives by "lignin specific" caffeic acid 3-O-methyltransferase · PMID 15081283 · 44 records
• Observation of aldicarb hydrolysis by a cocaine hydrolase · PMID 41716048 · 1 record
• Occurrence and properties of four forms of phosphoenolpyruvate carboxykinase in the chicken liver · PMID 4828524 · 40 records
• Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides · PMID 26324178 · 11 records
• Ohr (organic hydroperoxide resistance protein) possesses a previously undescribed activity, lipoyl-dependent peroxidase · PMID 20463026 · 6 records
• Oligomeric defects in soybean serine hydroxymethyltransferase 8: tetramer destabilization by A149T and other variants associated with soybean cyst nematode resistance · PMID 41914311 · 6 records
• Oligomeric State and Thermal Stability of Apo- and Holo- Human Ornithine δ-Aminotransferase · PMID 28345116 · 9 records
• Oligomerization and Catalytic Parameters of Human UDP-Glucuronosyltransferase 1A10: Expression and Characterization of the Recombinant Protein · PMID 30111624 · 7 records
• Oligomerization of Sulfolobus solfataricus signature amidase is promoted by acidic pH and high temperature · PMID 16243781 · 30 records
• Oligopeptidase B from Serratia proteamaculans. II. Enzymatic characteristics: substrate analysis, influence of calcium ions, pH and temperature dependences · PMID 21585325 · 29 records
• Oligopeptidase B from Trypanosoma evansi. A parasite peptidase that inactivates atrial natriuretic factor in the bloodstream of infected hosts · PMID 15644339 · 48 records
• Oligosaccharide oxidase for the enzymatic synthesis of glucosaminic acids · PMID 41844952 · 5 records
• Oligosaccharide preferences of beta1,4-galactosyltransferase-I: crystal structures of Met340His mutant of human beta1,4-galactosyltransferase-I with a pentasaccharide and trisaccharides of the… · PMID 16157350 · 10 records
• On the active site for hydrolysis of aryl amides and choline esters by human cholinesterases · PMID 16504521 · 12 records
• On the catalytic mechanism and stereospecificity of Escherichia coli L-threonine aldolase · PMID 24165453 · 18 records
• On the catalytic role of the active site residue E121 of E. coli L-aspartate oxidase · PMID 20600565 · 10 records
• On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosis · PMID 21303655 · 4 records
• On the functionality of a methionine sulfoxide reductase B from Trypanosoma cruzi · PMID 32682073 · 20 records
• On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase · PMID 9485426 · 12 records
• On the specificity and pH dependence of ficin-catalyzed hydrolyses. Some comparisons with bromelain specificity · PMID 4363754 · 38 records
• On the specificity of phospho-N-acetylmuramyl-pentapeptide translocase. The peptide subunit of uridine diphosphate-N-actylmuramyl-pentapeptide · PMID 4208473 · 17 records
• On the specificity of Pseudomonas aeruginosa alkaline proteinase with synthetic peptides · PMID 4199986 · 27 records
• One substrate, five products: reactions catalyzed by the dihydroneopterin aldolase from Mycobacterium tuberculosis · PMID 23150985 · 7 records
• One-carbon metabolism in plants: characterization of a plastid serine hydroxymethyltransferase · PMID 20518745 · 8 records
• One-pot sustainable synthesis of glucosylglycerate from starch and glycerol through artificial in vitro enzymatic cascade · PMID 38508282 · 2 records
• One-pot two-strain system based on glucaric acid biosensor for rapid screening of myo-inositol oxygenase mutations and glucaric acid production in recombinant cells · PMID 30125674 · 6 records
• One-site polarity switch enhances catalytic efficiency and stability of D-allulose 3-epimerase via flexibility-rigidity rebalancing · PMID 42218266 · 2 records
• One-Step Enzymatic Synthesis of 1-Tuliposide A Using Tuliposide-Converting Enzyme · PMID 30284210 · 4 records
• One-step purification and immobilization of thermophilic polyphosphate glucokinase from Thermobifida fusca YX: glucose-6-phosphate generation without ATP · PMID 21766194 · 6 records
• One-step purification of a recombinant beta-galactosidase using magnetic cellulose as a support: Rapid immobilization and high thermal stability · PMID 34883192 · 9 records
• Open and closed structures of L-arginine oxidase by cryo-electron microscopy and X-ray crystallography · PMID 39420599 · 6 records
• Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase · PMID 25644306 · 8 records
• Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between the Substrate and Positively Charged Residues · PMID 32011131 · 17 records
• Optimal electrostatic interactions between substrate and protein are essential for radical chemistry in ornithine 4,5-aminomutase · PMID 28528213 · 8 records
• Optimization of a high throughput screening platform to identify inhibitors of asymmetric diadenosine polyphosphatases · PMID 39521360 · 6 records
• Optimization of a small laccase by active-site redesign · PMID 23775916 · 8 records
• Optimization of D-amino acid oxidase for low substrate concentrations--towards a cancer enzyme therapy · PMID 19694805 · 6 records
• Optimizing an artificial metabolic pathway: engineering the cofactor specificity of Corynebacterium 2,5-diketo-D-gluconic acid reductase for use in vitamin C biosynthesis · PMID 12009883 · 46 records
• Ordered chimerogenesis applied to CYP2B P450 enzymes · PMID 27015760 · 30 records
• Orf135 from Escherichia coli Is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP · PMID 11053429 · 3 records
• Organ-specific human alcohol dehydrogenase: isolation and characterization of isozymes from testis · PMID 2936344 · 8 records
• Organization of the human mitochondrial hydrogen sulfide oxidation pathway · PMID 25225291 · 16 records
• Origin of cooperativity in the activation of fructose-1,6-bisphosphatase by Mg2+ · PMID 14978036 · 11 records
• Origin of the proton-transfer step in the cofactor-free (1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase: effect of the basicity of an active site His residue · PMID 24482238 · 6 records
• Ornithine cyclodeaminase/μ-crystallin homolog from the hyperthermophilic archaeon Thermococcus litoralis functions as a novel Δ(1)-pyrroline-2-carboxylate reductase involved in putative… · PMID 25161870 · 22 records
• Ornithine oxoacid aminotransferase found in AH 130 ascites hepatoma cells · PMID 7055619 · 16 records
• Ornithine transcarbamylase from Streptococcus faecalis and bovine liver. II. Multiple binding sites for carbamyl-P and L-norvaline, correlation with steady state kinetics · PMID 4622304 · 36 records
• Orotidine 5'-Monophosphate Decarboxylase: The Operation of Active Site Chains Within and Across Protein Subunits · PMID 32374983 · 10 records
• Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic properties · PMID 21849506 · 10 records
• Outer Membrane Protease OmpT-Based Strategy for Simplified Analysis of Histone Post-Translational Modifications by Mass Spectrometry · PMID 31775502 · 8 records
• Over-expression, purification, and kinetic analysis of Mycobacterium tuberculosis WecA · PMID 41507074 · 2 records
• Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae · PMID 17002315 · 5 records
• Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity · PMID 30744994 · 6 records
• Overexpression and characterization of dimeric and tetrameric forms of recombinant serine hydroxymethyltransferase from Bacillus stearothermophilus · PMID 12089472 · 6 records
• Overexpression and characterization of the chromosomal aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium · PMID 9145851 · 14 records
• Overexpression and characterization of two unknown proteins, YicI and YihQ, originated from Escherichia coli · PMID 15294295 · 3 records
• Overexpression and mutagenesis of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase. Role of cysteines and tyrosines in catalysis · PMID 8175784 · 32 records
• Overexpression of a novel thermostable and chloride-tolerant laccase from Thermus thermophilus SG0.5JP17-16 in Pichia pastoris and its application in synthetic dye decolorization · PMID 25790466 · 4 records
• Overexpression of Artemisia annua Cinnamyl Alcohol Dehydrogenase Increases Lignin and Coumarin and Reduces Artemisinin and Other Sesquiterpenes · PMID 29971081 · 3 records
• Overexpression of penicillin V acylase from Streptomyces lavendulae and elucidation of its catalytic residues · PMID 25501472 · 5 records
• Overexpression of thermostable meso-diaminopimelate dehydrogenase to redirect diaminopimelate pathway for increasing L-lysine production in Escherichia coli · PMID 30787467 · 18 records
• Overexpression, purification and characterization of Mycobacterium bovis BCG alcohol dehydrogenase · PMID 10336611 · 10 records
• Overexpression, purification, and characterization of the cloned metallo-beta-lactamase L1 from Stenotrophomonas maltophilia · PMID 9559809 · 29 records
• Overexpression, purification, and characterization of VanX, a D-, D-dipeptidase which is essential for vancomycin resistance in Enterococcus faecium BM4147 · PMID 7873524 · 7 records
• Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes · PMID 28062577 · 19 records
• Overlapping substrate specificities of benzaldehyde dehydrogenase (the xylC gene product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product) encoded by TOL plasmid pWW0 of… · PMID 7868591 · 10 records
• Oxalate accumulation and regulation is independent of glycolate oxidase in rice leaves · PMID 16595582 · 4 records
• Oxanosine Monophosphate Is a Covalent Inhibitor of Inosine 5'-Monophosphate Dehydrogenase · PMID 30746940 · 10 records
• Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes · PMID 17980859 · 24 records
• Oxidation of alcohols and reduction of aldehydes derived from methyl- and dimethylpyrenes by cDNA-expressed human alcohol dehydrogenases · PMID 18242813 · 39 records
• Oxidation of resveratrol catalyzed by soybean lipoxygenase · PMID 12617600 · 5 records
• Oxidative cyclization of N-methyl-dopa by a fungal flavoenzyme of the amine oxidase family · PMID 30194285 · 4 records
• Oxidative deamination of sulfur amino acids by bacterial and snake venom L-amino acid oxidase · PMID 5169142 · 9 records
• Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases · PMID 17493578 · 16 records
• Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH · PMID 20662781 · 7 records
• Oxylipin biosynthesis in spikemoss Selaginella moellendorffii: Molecular cloning and identification of divinyl ether synthases CYP74M1 and CYP74M3 · PMID 26776054 · 4 records
• Pa0148 from Pseudomonas aeruginosa catalyzes the deamination of adenine · PMID 21710971 · 20 records
• Paenibacillus sp. TS12 glucosylceramidase: kinetic studies of a novel sub-family of family 3 glycosidases and identification of the catalytic residues · PMID 14561218 · 6 records
• Pancreatic branched-chain-amino-acid aminotransferase · PMID 2853816 · 30 records
• Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea · PMID 19666462 · 3 records
• PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif · PMID 21788334 · 6 records
• Paramecium bursaria chlorella virus-1 encodes an unusual arginine decarboxylase that is a close homolog of eukaryotic ornithine decarboxylases · PMID 15190062 · 11 records
• Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues · PMID 25416785 · 3 records
• Partial purification and characterisation of sucrose synthase in sugarcane · PMID 15700416 · 12 records
• Partial purification and characterization of a soybean beta-glucosidase with high specific activity towards isoflavone conjugates · PMID 11730862 · 19 records
• Partial purification and characterization of L-lactate dehydrogenase isozymes from sweet potato roots · PMID 19425 · 10 records
• Partial purification and some properties of human liver alkaline phosphatase · PMID 945751 · 22 records
• Partial purification of human intestinal alkaline phosphatase with affinity chromotography. Some properties and interaction of concanavalin A with alkaline phosphatase · PMID 823966 · 16 records
• Partial purification, kinetic analysis, and amino acid sequence information of a flavonol 3-O-methyltransferase from Serratula tinctoria · PMID 15084728 · 4 records
• Partial reconstruction of flavonoid and isoflavonoid biosynthesis in yeast using soybean type I and type II chalcone isomerases · PMID 15778463 · 15 records
• Partial restoration of activity to Lactobacillus casei thymidylate synthase following inactivation by domain deletion · PMID 8180187 · 12 records
• Pasteurella multocida CMP-sialic acid synthetase and mutants of Neisseria meningitidis CMP-sialic acid synthetase with improved substrate promiscuity · PMID 21968653 · 14 records
• Pathogenic mutations in the carboxyl-terminal domain of glutaryl-CoA dehydrogenase: effects on catalytic activity and the stability of the tetramer · PMID 12948740 · 10 records
• Patulin Detoxification by Evolutionarily Divergent Reductases of Gluconobacter oxydans ATCC 621 · PMID 40066527 · 19 records
• Pcal_1311, an alcohol dehydrogenase homologue from Pyrobaculum calidifontis, displays NADH-dependent high aldehyde reductase activity · PMID 29022135 · 4 records
• Penicillin sulfone inhibitors of class D beta-lactamases · PMID 20086146 · 8 records
• Penicillium camemberti galacturonate reductase: C-1 oxidation/reduction of uronic acids and substrate inhibition mitigation by aldonic acids · PMID 31756465 · 27 records
• Penicillopepsin-JT2, a recombinant enzyme from Penicillium janthinellum and the contribution of a hydrogen bond in subsite S3 to k(cat) · PMID 10850809 · 48 records
• Peptidase specificity characterization of C- and N-terminal catalytic sites of angiotensin I-converting enzyme · PMID 10913258 · 66 records
• Peptide specificity of protein prenyltransferases is determined mainly by reactivity rather than binding affinity · PMID 16285735 · 19 records
• Peptidoglycan N-acetylglucosamine deacetylases from Bacillus cereus, highly conserved proteins in Bacillus anthracis · PMID 15961396 · 10 records
• Peptidyl-tRNA hydrolase from Sulfolobus solfataricus · PMID 12799450 · 5 records
• Perforation of the tunnel wall in carbamoyl phosphate synthetase derails the passage of ammonia between sequential active sites · PMID 15122899 · 36 records
• Perturbing the hydrophobic pocket of mandelate racemase to probe phenyl motion during catalysis · PMID 15966725 · 10 records
• pH and kinetic isotope effects on sarcosine oxidation by N-methyltryptophan oxidase · PMID 15723552 · 7 records
• pH and kinetic studies of chloroplast sedoheptulose-1,7-bisphosphatase from spinach (Spinacia oleracea) · PMID 2844169 · 4 records
• pH dependence of the enzymatic processing of collagen I by MMP-1 (fibroblast collagenase), MMP-2 (gelatinase A), and MMP-14 ectodomain · PMID 20549272 · 24 records
• pH dependence of the reaction catalyzed by yeast Mg-enolase · PMID 9790688 · 44 records
• pH dependence, substrate specificity and inhibition of human kynurenine aminotransferase I · PMID 15606768 · 18 records
• pH-dependence of the triose phosphate isomerase reaction · PMID 4643319 · 26 records
• PH-Dependent Enantioselectivity of D-amino Acid Oxidase in Aqueous Solution · PMID 28592826 · 21 records
• pH-rate profiles of L-arabinitol 4-dehydrogenase from Hypocrea jecorina and its application in L-xylulose production · PMID 24342239 · 15 records
• Phage-assisted continuous evolution of enzymes for noncanonical tyrosine biosynthesis · PMID 42721086 · 12 records
• Phenanthrene degradation by a flavoprotein monooxygenase from Phanerodontia chrysosporium · PMID 39898659 · 19 records
• Phenol hydroxylase from Bacillus thermoglucosidasius A7, a two-protein component monooxygenase with a dual role for FAD · PMID 12968028 · 11 records
• Phenol hydroxylase from yeast. Reaction with phenol derivatives · PMID 569150 · 30 records
• Phenol sulfotransferases · PMID 447677 · 34 records
• Phenolic metabolism in Sarcandra glabra is mediated by distinct BAHD hydroxycinnamoyltransferases · PMID 40029908 · 24 records
• Phenolic metabolism in the hornwort Anthoceros agrestis: 4-coumarate CoA ligase and 4-hydroxybenzoate CoA ligase · PMID 32405654 · 17 records
• Phenolic substrates and suicide inactivation of tyrosinase: kinetics and mechanism · PMID 18647136 · 13 records
• Phenotypic and biochemical characterization of the class C β-lactamase, PAC-1 · PMID 42639739 · 9 records
• Phenotypic and genotypic characterization of HMB-3, a metallo-beta-lactamase from Pseudomonas asiatica · PMID 42089879 · 14 records
• Phenylalanine ammonia lyase from Arabidopsis thaliana (AtPAL2): A potent MIO-enzyme for the synthesis of non-canonical aromatic alpha-amino acids: Part I: Comparative characterization to the enzymes… · PMID 28392421 · 8 records
• Phenylalanine ammonia-lyase (PAL) from tobacco (Nicotiana tabacum): characterization of the four tobacco PAL genes and active heterotetrameric enzymes · PMID 19725811 · 12 records
• Phenylalanine ammonia-lyase: the use of its broad substrate specificity for mechanistic investigations and biocatalysis--synthesis of L-arylalanines · PMID 11039531 · 11 records
• Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases · PMID 17726025 · 10 records
• Phosphate sensitivity of KPC-2: a hidden variable in β-lactamase kinetics · PMID 41616264 · 48 records
• Phosphinothricin Acetyltransferases Identified Using In Vivo, In Vitro, and Bioinformatic Analyses · PMID 27694229 · 8 records
• Phosphodeoxyribosyltransferases, designed enzymes for deoxyribonucleotides synthesis · PMID 23325804 · 10 records
• Phosphoenolpyruvate carboxykinase assayed at physiological concentrations of metal ions has a high affinity for CO2 · PMID 11788761 · 20 records
• Phosphoenolpyruvate synthetase from the hyperthermophilic archaeon Pyrococcus furiosus · PMID 11133966 · 5 records
• Phosphoenolpyruvate- and ATP-dependent dihydroxyacetone kinases: covalent substrate-binding and kinetic mechanism · PMID 15476397 · 17 records
• Phosphofructokinases A and B from Mycobacterium tuberculosis Display Different Catalytic Properties and Allosteric Regulation · PMID 33540748 · 9 records
• Phosphoglucose isomerase from human erythrocyte. Preparation and properties · PMID 5135316 · 3 records
• Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea · PMID 33234025 · 3 records
• Phosphoglycerate mutase. Kinetics and effects of salts on the mutase and bisphosphoglycerate phosphatase activities of the enzyme from chicken breast muscle · PMID 213437 · 19 records
• Phosphoketolases from Lactococcus lactis, Leuconostoc mesenteroides and Pseudomonas aeruginosa: dissimilar sequences, similar substrates but distinct enzymatic characteristics · PMID 24740691 · 6 records
• Phospholipid hydroperoxide glutathione peroxidase activity of human glutathione transferases · PMID 9576856 · 9 records
• Phosphomevalonate kinase: functional investigation of the recombinant human enzyme · PMID 16519518 · 20 records
• Phosphomimetic T335D Mutation of Hydroxypyruvate Reductase 1 Modifies Cofactor Specificity and Impacts Arabidopsis Growth in Air · PMID 32156771 · 24 records
• Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria · PMID 11278255 · 4 records
• Phosphoramidate pronucleotides: a comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins · PMID 17217311 · 40 records
• Phosphorothioate analogues of adenosine triphosphate as substrates of the mevalonate kinase reaction · PMID 6329303 · 22 records
• Phosphorylation of deoxycytidine kinase on Ser-74: impact on kinetic properties and nucleoside analog activation in cancer cells · PMID 22490700 · 16 records
• Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activities · PMID 15946941 · 4 records
• Phosphorylation of Human Choline Kinase Beta by Protein Kinase A: Its Impact on Activity and Inhibition · PMID 27149373 · 9 records
• Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis · PMID 21143326 · 4 records
• Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity · PMID 27365393 · 6 records
• Phosphorylation of pyrimidine L-deoxynucleoside analog diphosphates. Kinetics of phosphorylation and dephosphorylation of nucleoside analog diphosphates and triphosphates by 3-phosphoglycerate… · PMID 12080078 · 70 records
• Phosphorylation of ribavirin and viramidine by adenosine kinase and cytosolic 5'-nucleotidase II: Implications for ribavirin metabolism in erythrocytes · PMID 15917509 · 13 records
• Phosphotyrosyl peptides and analogues as substrates and inhibitors of purple acid phosphatases · PMID 15047187 · 10 records
• Phylogenetic analysis and in-depth characterization of functionally and structurally diverse CE5 cutinases · PMID 34653507 · 25 records
• Phylogenetic analysis of ADP-glucose pyrophosphorylase subunits reveals a role of subunit interfaces in the allosteric properties of the enzyme · PMID 19625637 · 30 records
• Phylogenetic diversity and the structural basis of substrate specificity in the beta/alpha-barrel fold basic amino acid decarboxylases · PMID 17626020 · 26 records
• Phylogenetic investigation of the 100 kDa hexokinase enzyme family with the topiary ancestral sequence reconstruction pipeline · PMID 42267741 · 23 records
• Physical and chemical characterization of a horse serum carboxylesterase · PMID 3196030 · 17 records
• Physical and enzymatic properties of a class II alcohol dehydrogenase isozyme of human liver: pi-ADH · PMID 6397223 · 13 records
• Physical and enzymatic properties of a class III isozyme of human liver alcohol dehydrogenase: chi-ADH · PMID 6375718 · 9 records
• Physiological and biochemical characterization of three nucleoside diphosphate kinase isozymes from rice (Oryza sativa L.) · PMID 21897044 · 18 records
• Physiological function and kinetic mechanism of human liver alcohol dehydrogenase as 5 beta-cholestane-3 alpha,7 alpha,12 alpha,26-tetrol dehydrogenase · PMID 6338006 · 6 records
• Picosecond-resolved fluorescence studies of substrate and cofactor-binding domain mutants in a thermophilic alcohol dehydrogenase uncover an extended network of communication · PMID 25314615 · 12 records
• Piezo-adapted 3-isopropylmalate dehydrogenase of the obligate piezophile Shewanella benthica DB21MT-2 isolated from the 11,000-m depth of the Mariana Trench · PMID 19897891 · 12 records
• Pig liver carnitine palmitoyltransferase. Chimera studies show that both the N- and C-terminal regions of the enzyme are important for the unusual high malonyl-CoA sensitivity · PMID 11790778 · 22 records
• Pig muscle aldehyde reductase. Identity of pig muscle aldehyde reductase with pig lens aldose reductase and with the low Km aldehyde reductase of pig brain and pig kidney · PMID 6339488 · 16 records
• Plant ALDH10 family: identifying critical residues for substrate specificity and trapping a thiohemiacetal intermediate · PMID 23408433 · 30 records
• Plant carbonic anhydrase. Properties and carbon dioxide hydration kinetics · PMID 4210017 · 26 records
• Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly · PMID 29187521 · 12 records
• Plant Glyoxylate/Succinic Semialdehyde Reductases: Comparative Biochemical Properties, Function during Chilling Stress, and Subcellular Localization · PMID 28855911 · 18 records
• Plant nucleoside N-ribohydrolases: riboside binding and role in nitrogen storage mobilization · PMID 38044809 · 56 records
• Plant-type phytoene desaturase: Functional evaluation of structural implications · PMID 29176862 · 5 records
• Plants Possess a Cyclic Mitochondrial Metabolic Pathway similar to the Mammalian Metabolic Repair Mechanism Involving Malate Dehydrogenase and l-2-Hydroxyglutarate Dehydrogenase · PMID 26203119 · 5 records
• Plants utilize a highly conserved system for repair of NADH and NADPH hydrates · PMID 24599492 · 4 records
• Plasmodium falciparum Apicomplexan-Specific Glucosamine-6-Phosphate N-Acetyltransferase Is Key for Amino Sugar Metabolism and Asexual Blood Stage Development · PMID 33082260 · 12 records
• Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis · PMID 19736991 · 14 records
• Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase · PMID 18729382 · 8 records
• Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine · PMID 21992006 · 4 records
• Plasmodium falciparum: asparagine mutant at residue 108 of dihydrofolate reductase is an optimal antifolate-resistant single mutant · PMID 9371090 · 8 records
• Plasticity of the quinone-binding site of the complex II homolog quinol:fumarate reductase · PMID 23836905 · 49 records
• Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme · PMID 11294621 · 17 records
• Pleiotropic effects of ATP.Mg2+ binding in the catalytic cycle of ubiquitin-activating enzyme · PMID 16595681 · 22 records
• Point mutation (R153H or R153C) in Escherichia coli isocitrate dehydrogenase: Biochemical characterization and functional implication · PMID 27406240 · 10 records
• Point mutations (Q19P and N23K) increase the operational solubility of a 2alpha-O-benzoyltransferase that conveys various acyl groups from CoA to a taxane acceptor · PMID 20108947 · 17 records
• Poly(C) synthesis by class I and class II CCA-adding enzymes · PMID 11926813 · 10 records
• Poly-lysine supported cross-linked enzyme aggregates of penicillin G acylase and its application in synthesis of β-lactam antibiotics · PMID 31381925 · 9 records
• Polyamine oxidase 7 is a terminal catabolism-type enzyme in Oryza sativa and is specifically expressed in anthers · PMID 24634478 · 14 records
• Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS-3 · PMID 41804212 · 12 records
• Polyol-pathway enzymes of human brain. Partial purification and properties of aldose reductase and hexonate dehydrogenase · PMID 6773519 · 16 records
• Polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) isozyme surface charge governs charge substrate preferences to modulate mucin type O-glycosylation · PMID 37555669 · 10 records
• Polyphosphate/ATP-dependent NAD kinase of Corynebacterium glutamicum: biochemical properties and impact of ppnK overexpression on lysine production · PMID 20180116 · 11 records
• Porcine serum maltase-glucoamylase: structure, kinetics, and inhibition · PMID 41534875 · 30 records
• Possible role of a histidine residue in the substrate specificity of yeast d-aspartate oxidase · PMID 26519738 · 8 records
• Possible role of inter-domain salt bridges in oligopeptidase B from Trypanosoma brucei: critical role of Glu172 of non-catalytic β-propeller domain in catalytic activity and Glu490 of catalytic… · PMID 23946505 · 25 records
• Post-translational regulation of human D-3-phosphoglycerate dehydrogenase in Alzheimer's disease · PMID 41711160 · 13 records
• Potato tuber isoapyrases: substrate specificity, affinity labeling, and proteolytic susceptibility · PMID 15896365 · 22 records
• Potentiometric and further kinetic characterization of the flavin-binding domain of Saccharomyces cerevisiae flavocytochrome b2. Inhibition by anions binding in the active site · PMID 17373777 · 20 records
• PqsE of Pseudomonas aeruginosa Acts as Pathway-Specific Thioesterase in the Biosynthesis of Alkylquinolone Signaling Molecules · PMID 25960261 · 5 records
• PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase · PMID 27129774 · 57 records
• Pre-steady-state kinetics of Bacillus licheniformis 1,3-1,4-beta-glucanase: evidence for a regulatory binding site · PMID 12568655 · 20 records
• Precise Probing of Residue Roles by NRPS Code Swapping: Mutation, Enzymatic Characterization, Modeling, and Substrate Promiscuity of Aryl Acid Adenylation Domains · PMID 31894971 · 15 records
• Predatory myxobacteria lay at the cross-roads of metallo-β-lactamase evolution · PMID 42286160 · 63 records
• Preferential hydrolysis of aberrant intermediates by the type II thioesterase in Escherichia coli nonribosomal enterobactin synthesis: substrate specificities and mutagenic studies on the… · PMID 19193103 · 23 records
• Prenylation of flavonoids by using a dimethylallyltryptophan synthase, 7-DMATS, from Aspergillus fumigatus · PMID 23106077 · 6 records
• Preparative and Kinetic Analysis of β-1,4- and β-1,3-Glucan Phosphorylases Informs Access to Human Milk Oligosaccharide Fragments and Analogues Thereof · PMID 31657512 · 14 records
• Preparative use of isolated CYP102 monooxygenases -- a critical appraisal · PMID 16716428 · 13 records
• Presence of a closely related subgroup in the aldo-ketoreductase family of the mouse · PMID 7851421 · 5 records
• Primary structure, physicochemical properties, and chemical modification of NAD(+)-dependent D-lactate dehydrogenase. Evidence for the presence of Arg-235, His-303, Tyr-101, and Trp-19 at or near… · PMID 1569100 · 8 records
• Primordial-like enzymes from bacteria with reduced genomes · PMID 28640457 · 13 records
• Probing active site chemistry in SHV beta-lactamase variants at Ambler position 244. Understanding unique properties of inhibitor resistance · PMID 16803899 · 15 records
• Probing active-site residues of pyranose 2-oxidase from Trametes multicolor by semi-rational protein design · PMID 19370721 · 36 records
• Probing allosteric binding sites of the maize endosperm ADP-glucose pyrophosphorylase · PMID 19889875 · 13 records
• Probing catalysis by Escherichia coli dTDP-glucose-4,6-dehydratase: identification and preliminary characterization of functional amino acid residues at the active site · PMID 11380254 · 21 records
• Probing domain mobility in a flavocytochrome · PMID 15109257 · 8 records
• Probing hydrogen-bonding interactions in the active site of medium-chain acyl-CoA dehydrogenase using Raman spectroscopy · PMID 14529297 · 3 records
• Probing mammalian spermine oxidase enzyme-substrate complex through molecular modeling, site-directed mutagenesis and biochemical characterization · PMID 20839014 · 3 records
• Probing remote residues important for catalysis in Escherichia coli ornithine transcarbamoylase · PMID 32027716 · 30 records
• Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis · PMID 11876827 · 89 records
• Probing the acceptor active site organization of the human recombinant β1,4-galactosyltransferase 7 and design of xyloside-based inhibitors · PMID 25568325 · 20 records
• Probing the active center gorge of acetylcholinesterase by fluorophores linked to substituted cysteines · PMID 10779503 · 8 records
• Probing the active site loop motif of murine ferrochelatase by random mutagenesis · PMID 14981080 · 12 records
• Probing the acyl-binding pocket of aminoacylase-1 · PMID 18341290 · 43 records
• Probing the beta-1,3:1,4 glucanase, CtLic26A, with a thio-oligosaccharide and enzyme variants · PMID 18292875 · 20 records
• Probing the catalytic mechanism of bovine CD38/NAD+ glycohydrolase by site directed mutagenesis of key active site residues · PMID 24721563 · 12 records
• Probing the catalytic mechanism of Escherichia coli amine oxidase using mutational variants and a reversible inhibitor as a substrate analogue · PMID 11985492 · 11 records
• Probing the catalytic mechanism of prephenate dehydratase by site-directed mutagenesis of the Escherichia coli P-protein dehydratase domain · PMID 10769128 · 24 records
• Probing the catalytic mechanism of S-ribosylhomocysteinase (LuxS) with catalytic intermediates and substrate analogues · PMID 19099445 · 10 records
• Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 · PMID 19860825 · 33 records
• Probing the catalytically essential residues of the alpha-L-arabinofuranosidase from Thermobacillus xylanilyticus · PMID 11842234 · 17 records
• Probing the chemical steps of nitroalkane oxidation catalyzed by 2-nitropropane dioxygenase with solvent viscosity, pH, and substrate kinetic isotope effects · PMID 17105207 · 8 records
• Probing the conformational change of Escherichia coli undecaprenyl pyrophosphate synthase during catalysis using an inhibitor and tryptophan mutants · PMID 11744728 · 15 records
• Probing the determinants of coenzyme specificity in Peptostreptococcus asaccharolyticus glutamate dehydrogenase by site-directed mutagenesis · PMID 17850332 · 12 records
• Probing the determinants of substrate specificity of a feruloyl esterase, AnFaeA, from Aspergillus niger · PMID 16128806 · 19 records
• Probing the dynamics of a mobile loop above the active site of L1, a metallo-beta-lactamase from Stenotrophomonas maltophilia, via site-directed mutagenesis and stopped-flow fluorescence… · PMID 15271998 · 24 records
• Probing the essential catalytic residues and substrate affinity in the thermoactive Bacillus stearothermophilus US100 L-arabinose isomerase by site-directed mutagenesis · PMID 17337581 · 7 records
• Probing the function of Mycobacterium tuberculosis catalase-peroxidase by site-directed mutagenesis · PMID 16315359 · 15 records
• Probing the H-protein-induced conformational change and the function of the N-terminal region of Escherichia coli T-protein of the glycine cleavage system by limited proteolysis · PMID 12531904 · 16 records
• Probing the Human 4-Oxo-l-proline Reductase-Catalyzed Reaction by Deuterium Kinetic and Equilibrium Isotope Effects · PMID 42462138 · 6 records
• Probing the importance of hydrogen bonds in the active site of the subtilisin nattokinase by site-directed mutagenesis and molecular dynamics simulation · PMID 16411898 · 5 records
• Probing the interactions between the folding elements early in the folding of Escherichia coli dihydrofolate reductase by systematic sequence perturbation analysis · PMID 15740745 · 52 records
• Probing the location and function of the conserved histidine residue of phosphoglucose isomerase by using an active site directed inhibitor N-bromoacetylethanolamine phosphate · PMID 10595547 · 6 records
• Probing the mechanism of the bifunctional enzyme ketol-acid reductoisomerase by site-directed mutagenesis of the active site · PMID 15654896 · 44 records
• Probing the molecular basis of substrate specificity, stereospecificity, and catalysis in the class II pyruvate aldolase, BphI · PMID 21425833 · 27 records
• Probing the molecular determinant for the catalytic efficiency of L-arabinose isomerase from Bacillus licheniformis · PMID 20048061 · 5 records
• Probing the NADH- and Methyl Red-binding site of a FMN-dependent azoreductase (AzoA) from Enterococcus faecalis · PMID 22387379 · 21 records
• Probing the NADPH-binding site of Escherichia coli flavodoxin oxidoreductase · PMID 11085917 · 20 records
• Probing the origins of glutathione biosynthesis through biochemical analysis of glutamate-cysteine ligase and glutathione synthetase from a model photosynthetic prokaryote · PMID 23170977 · 21 records
• Probing the promiscuous active site of myo-inositol dehydrogenase using synthetic substrates, homology modeling, and active site modification · PMID 17539607 · 20 records
• Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase · PMID 27172425 · 8 records
• Probing the role of an invariant active site His in family GH1 β-glycosidases · PMID 31072150 · 6 records
• Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography · PMID 15788415 · 17 records
• Probing the role of cysteine residues in glucosamine-1-phosphate acetyltransferase activity of the bifunctional GlmU protein from Escherichia coli: site-directed mutagenesis and characterization of… · PMID 9733680 · 20 records
• Probing the role of glutamic acid 139 of Anabaena ferredoxin-NADP+ reductase in the interaction with substrates · PMID 12383252 · 34 records
• Probing the role of highly conserved residues in triosephosphate isomerase--analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzyme · PMID 26206206 · 5 records
• Probing the role of metal ions in the catalysis of Helicobacter pylori 3-deoxy-D-manno-octulosonate-8-phosphate synthase using a transient kinetic analysis · PMID 14701842 · 5 records
• Probing the role of the C-terminus of Bacillus subtilis chorismate mutase by a novel random protein-termination strategy · PMID 11087356 · 7 records
• Probing the role of the fully conserved Cys126 in triosephosphate isomerase by site-specific mutagenesis--distal effects on dimer stability · PMID 21447068 · 6 records
• Probing the role of the hyper-reactive histidine residue of arginase · PMID 16266687 · 15 records
• Probing the roles of conserved arginine-44 of Escherichia coli dihydrofolate reductase in its function and stability by systematic sequence perturbation analysis · PMID 20043879 · 20 records
• Probing the roles of key residues in the unique regulatory NADH binding site of type II citrate synthase of Escherichia coli · PMID 12824188 · 18 records
• Probing the Signal Transduction Mechanism of the Light-Activated Adenylate Cyclase OaPAC Using Unnatural Amino Acid Mutagenesis · PMID 39844630 · 4 records
• Probing the specificity determinants of amino acid recognition by arginase · PMID 19093830 · 9 records
• Probing the specificity of the subclass B3 FEZ-1 metallo-beta-lactamase by site-directed mutagenesis · PMID 15159411 · 70 records
• Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis · PMID 16336198 · 62 records
• Probing the Substrate Promiscuity of Isopentenyl Phosphate Kinase as a Platform for Hemiterpene Analogue Production · PMID 30998839 · 10 records
• Probing the substrate specificities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched fluorescent peptides · PMID 19302215 · 50 records
• Procarboxypeptidase A from the insect pest Helicoverpa armigera and its derived enzyme. Two forms with new functional properties · PMID 12846836 · 7 records
• Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci · PMID 10021417 · 35 records
• Product formation controlled by substrate dynamics in leukotriene A4 hydrolase · PMID 24333438 · 4 records
• Production and characterisation of AoSOX2 from Aspergillus oryzae, a novel flavin-dependent sulfhydryl oxidase with good pH and temperature stability · PMID 21327412 · 5 records
• Production and characterization of bifunctional enzymes. Domain swapping to produce new bifunctional enzymes in the aspartate pathway · PMID 11888289 · 9 records
• Production and Characterization of Recombinant Wild Type Uricase from Indonesian Coelacanth (L. menadoensis) and Improvement of Its Thermostability by In Silico Rational Design and Disulphide… · PMID 30871218 · 6 records
• Production and characterization of the Talaromyces stipitatus feruloyl esterase FAEC in Pichia pastoris: identification of the nucleophilic serine · PMID 12767807 · 3 records
• Production of Hydroxy Acids: Selective Double Oxidation of Diols by Flavoprotein Alcohol Oxidase · PMID 31912947 · 9 records
• Production of Xylooligosaccharides (XOSs) with Anti-inflammatory and Prebiotic Activities Using Recombinant Endo-1,4-β-xylanases from Bacillus subtilis · PMID 41838424 · 2 records
• Production, isolation and characterization of a sterol esterase from Ophiostoma piceae · PMID 12479402 · 9 records
• Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7 · PMID 12732193 · 3 records
• Profactor IX propeptide and glutamate substrate binding sites on the vitamin K-dependent carboxylase identified by site-directed mutagenesis · PMID 8663364 · 33 records
• Profiling Cellular Substrates of Lysine Acetyltransferases GCN5 and p300 with Orthogonal Labeling and Click Chemistry · PMID 28426192 · 10 records
• Progress Curve Analysis Within BioCatNet: Comparing Kinetic Models for Enzyme-Catalyzed Self-Ligation · PMID 29999245 · 20 records
• Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria · PMID 25697095 · 7 records
• Promiscuity in the part-phosphorylative Entner-Doudoroff pathway of the archaeon Sulfolobus solfataricus · PMID 16330030 · 5 records
• Promiscuous Transferases Malonylate Furaneol Glucoside in Fragaria × ananassa · PMID 41640380 · 10 records
• Promising properties of a formate dehydrogenase from a methanol-assimilating yeast Ogataea parapolymorpha DL-1 in His-tagged form · PMID 23715855 · 2 records
• Properties and catalytic activities of MICAL1, the flavoenzyme involved in cytoskeleton dynamics, and modulation by its CH, LIM and C-terminal domains · PMID 26845023 · 15 records
• Properties and distribution of a metallo-β-lactamase (ALI-1) from the fish pathogen Aliivibrio salmonicida LFI1238 · PMID 25362569 · 13 records
• Properties and kinetic analysis of UDP-glucose dehydrogenase from group A streptococci. Irreversible inhibition by UDP-chloroacetol · PMID 9013585 · 2 records
• Properties and physiological functions of UDP-sugar pyrophosphorylase in Arabidopsis · PMID 17341835 · 8 records
• Properties and regulation of the bifunctional enzyme HPr kinase/phosphatase in Bacillus subtilis · PMID 12411438 · 16 records
• Properties and tissue distribution of mouse monomeric carbonyl reductase · PMID 9743262 · 21 records
• Properties of a class C beta-lactamase from Serratia marcescens · PMID 3548700 · 18 records
• Properties of a novel D-stereospecific aminopeptidase from Ochrobactrum anthropi · PMID 2760064 · 16 records
• Properties of an alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix K1 · PMID 16233615 · 23 records
• Properties of bacteriophage T4 thymidylate synthase following mutagenic changes in the active site and folate binding region · PMID 2271601 · 14 records
• Properties of Malic Enzyme from the Aerobic Methanotroph Methylosinus trichosporium · PMID 31228930 · 6 records
• Properties of membrane-bound and solubilized forms of alkaline phosphatase from human liver · PMID 3921059 · 19 records
• Properties of meso-alpha,epsilon-diaminopimelate D-dehydrogenase from Bacillus sphaericus · PMID 7430138 · 5 records
• Properties of purified methylmalonate semialdehyde dehydrogenase of Pseudomonas aeruginosa · PMID 4314598 · 8 records
• Properties of pyranose dehydrogenase purified from the litter-degrading fungus Agaricus xanthoderma · PMID 17227387 · 22 records
• Properties of recombinant human cytosolic sialidase HsNEU2. The enzyme hydrolyzes monomerically dispersed GM1 ganglioside molecules · PMID 14613940 · 14 records
• Properties of recombinant Strep-tagged and untagged hyperthermophilic D-arabitol dehydrogenase from Thermotoga maritima · PMID 21347726 · 10 records
• Properties of serine:glyoxylate aminotransferase purified from Arabidopsis thaliana leaves · PMID 18235971 · 10 records
• Properties of short-chain dehydrogenase/reductase RalR1: characterization of purified enzyme, its orientation in the microsomal membrane, and distribution in human tissues and cell lines · PMID 14674758 · 12 records
• Properties of the 40 kDa antigen of Mycobacterium tuberculosis, a functional L-alanine dehydrogenase · PMID 10527947 · 5 records
• Properties of the thermostable glutamate dehydrogenase of the mesophilic anaerobe Peptostreptoccus asaccharolyticus purified by a novel method after over-expression in an Escherichia coli host · PMID 15727821 · 7 records
• Properties of tryptophan indole-lyase from a piezophilic bacterium, Photobacterium profundum SS9 · PMID 21081107 · 7 records
• Properties, intracellular localization, and stage-specific expression of membrane-bound beta-glucosidase, BglM1, from Physarum polycephalum · PMID 18395487 · 10 records
• Propionate metabolism in Desulfurella acetivorans · PMID 40012784 · 5 records
• Propionyl-coenzyme A synthase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO2 fixation · PMID 11821399 · 6 records
• Propionyl-coenzyme A synthetases of Ralstonia solanacearum and Salmonella choleraesuis display atypical kinetics · PMID 14706841 · 12 records
• Proposal of metagenomic-origin LRA-5 as a precursor of active β-lactamases through Tyr69Gln and Val166Glu amino acid substitutions: a functional and structural analysis · PMID 41312992 · 16 records
• Proposed mechanism and functional amino acid residues of malonyl-CoA:anthocyanin 5-O-glucoside-6'''-O-malonyltransferase from flowers of Salvia splendens, a member of the versatile plant… · PMID 12578391 · 16 records
• Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP⁺ binding site · PMID 30583861 · 8 records
• Prospecting for unannotated enzymes: discovery of a 3',5'-nucleotide bisphosphate phosphatase within the amidohydrolase superfamily · PMID 24401123 · 12 records
• Prostaglandin endoperoxide H synthases: peroxidase hydroperoxide specificity and cyclooxygenase activation · PMID 17462992 · 44 records
• Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7 · PMID 19010934 · 11 records
• Protease and helicase activities of hepatitis C virus genotype 4, 5, and 6 NS3-NS4A proteins · PMID 19944069 · 5 records
• Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design · PMID 25621824 · 15 records
• Protein arginine N-methyltransferase 2 plays a noncatalytic role in the histone methylation activity of PRMT1 · PMID 37863263 · 9 records
• Protein engineering of a bacterial N-acyl-d-glucosamine 2-epimerase for improved stability under process conditions · PMID 27178797 · 11 records
• Protein engineering of Aspergillus awamori glucoamylase to increase its pH optimum · PMID 9681871 · 16 records
• Protein engineering of class-A non-specific acid phosphatase (PhoN) of Salmonella typhimurium: modulation of the pH-activity profile · PMID 16901752 · 14 records
• Protein engineering of Sulfolobus solfataricus maltooligosyltrehalose synthase to alter its selectivity · PMID 17567140 · 21 records
• Protein engineering of the relative specificity of glucoamylase from Aspergillus awamori based on sequence similarities between starch-degrading enzymes · PMID 7716159 · 13 records
• Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites · PMID 1610791 · 15 records
• Protein engineering of α2,3/2,6-sialyltransferase to improve the yield and productivity of in vitro sialyllactose synthesis · PMID 24142961 · 24 records
• Protein engineering studies of dichloromethane dehalogenase/glutathione S-transferase from Methylophilus sp. strain DM11. Ser12 but not Tyr6 is required for enzyme activity · PMID 8706748 · 13 records
• Protein engineering tests of a homology model of Plasmodium falciparum lactate dehydrogenase · PMID 9051732 · 15 records
• Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity · PMID 18985644 · 38 records
• Protein Language Model-Guided Engineering of a 2,3-Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α-Hydroxy Ketones · PMID 41580984 · 11 records
• Protein loops are major contributors to DNA strand separation and high-fidelity substrate recognition for DNA methyltransferase CcrM · PMID 41887600 · 7 records
• Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases · PMID 20521764 · 44 records
• Protein O-Linked Mannose β-1,4-N-Acetylglucosaminyl-transferase 2 (POMGNT2) Is a Gatekeeper Enzyme for Functional Glycosylation of α-Dystroglycan · PMID 27932460 · 11 records
• Protein radicals in fungal versatile peroxidase: catalytic tryptophan radical in both compound I and compound II and studies on W164Y, W164H, and W164S variants · PMID 19158088 · 3 records
• Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus. Unusual methyl-accepting affinity for D-aspartyl and N-succinyl-containing peptides · PMID 11694513 · 16 records
• Protein STM3547 From Salmonella typhimurium Is a Phosphofructose Kinase B-Type Enzyme With Ribose Kinase Activity · PMID 42249657 · 6 records
• Protein-glutaminase from Chryseobacterium proteolyticum, an enzyme that deamidates glutaminyl residues in proteins. Purification, characterization and gene cloning · PMID 11231294 · 9 records
• Protein-protein interactions and substrate channeling in orthologous and chimeric aldolase-dehydrogenase complexes · PMID 22316175 · 27 records
• Proteolysin, a novel highly thermostable and cosolvent-compatible protease from the thermophilic bacterium Coprothermobacter proteolyticus · PMID 23851086 · 21 records
• Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors · PMID 18296439 · 12 records
• Protonation of a neutral (S)-beta-bisabolene intermediate is involved in (S)-beta-macrocarpene formation by the maize sesquiterpene synthases TPS6 and TPS11 · PMID 18524777 · 2 records
• Proximal FAD histidine residue influences interflavin electron transfer in cytochrome P450 reductase and methionine synthase reductase · PMID 24589657 · 15 records
• Proximal mutations at the type 1 copper site of CotA laccase: spectroscopic, redox, kinetic and structural characterization of I494A and L386A mutants · PMID 18307408 · 9 records
• Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity · PMID 40057486 · 7 records
• Pseudomonas aeruginosa Exopolyphosphatase Is Also a Polyphosphate: ADP Phosphotransferase · PMID 26576296 · 15 records
• Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl-CoA reductase. Characterization and chemical modification · PMID 2681185 · 11 records
• Pterocarpan synthase (PTS) structures suggest a common quinone methide-stabilizing function in dirigent proteins and proteins with dirigent-like domains · PMID 32565424 · 12 records
• Purification and biochemical characterization of a pyruvate-specific class II aldolase, HpaI · PMID 15996099 · 4 records
• Purification and biochemical characterization of IMP-13 metallo-beta-lactamase · PMID 20974864 · 16 records
• Purification and biochemical characterization of Mur ligases from Staphylococcus aureus · PMID 20659527 · 13 records
• Purification and biochemical characterization of recombinant rice UDP-arabinopyranose mutase generated in insect cells · PMID 20057139 · 4 records
• Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB · PMID 11600501 · 6 records
• Purification and biochemical properties of an N-hydroxyarylamine O-acetyltransferase from Escherichia coli · PMID 10806332 · 11 records
• Purification and catalytic properties of L-valine dehydrogenase from Streptomyces cinnamonensis · PMID 2803248 · 15 records
• Purification and catalytic properties of two manganese peroxidase isoenzymes from Pleurotus eryngii · PMID 8647081 · 16 records
• Purification and characterisation of an alpha-glucan phosphorylase from the thermophilic bacterium Thermus thermophilus · PMID 8706700 · 15 records
• Purification and characterisation of glyoxalase II from human red blood cells · PMID 8504817 · 4 records
• Purification and Characterisation of Malate Dehydrogenase From Synechocystis sp. PCC 6803: Biochemical Barrier of the Oxidative Tricarboxylic Acid Cycle · PMID 30057585 · 16 records
• Purification and characteristics of an enzyme with both bilirubin oxidase and laccase activities from mycelium of the basidiomycete Pleurotus ostreatus · PMID 19916914 · 5 records
• Purification and characterization of 2-deoxy-scyllo-inosose synthase derived from Bacillus circulans. A crucial carbocyclization enzyme in the biosynthesis of 2-deoxystreptamine-containing… · PMID 10344560 · 2 records
• Purification and characterization of 5-ketofructose reductase from Erwinia citreus · PMID 3178725 · 7 records
• Purification and characterization of 6-phosphogluconate dehydrogenase from the wing-polymorphic cricket, Gryllus firmus, and assessment of causes of morph-differences in enzyme activity · PMID 24726622 · 14 records
• Purification and characterization of a Bacillus sp. SAM1606 thermostable alpha-glucosidase with transglucosylation activity · PMID 7764968 · 17 records
• Purification and characterization of a Baeyer-Villiger mono-oxygenase from Rhodococcus erythropolis DCL14 involved in three different monocyclic monoterpene degradation pathways · PMID 10769172 · 6 records
• Purification and characterization of a beta-glucosidase from rye (Secale cereale L.) seedlings · PMID 10773341 · 8 records
• Purification and characterization of a beta-lactamase from Haemophilus ducreyi in Escherichia coli · PMID 11570857 · 7 records
• Purification and characterization of a coagulant enzyme, okinaxobin II, from Trimeresurus okinavensis (himehabu snake) venom which release fibrinopeptides A and B · PMID 7725319 · 6 records
• Purification and characterization of a coenzyme-A-dependent succinate-semialdehyde dehydrogenase from Clostridium kluyveri · PMID 8444151 · 5 records
• Purification and characterization of a glycoside hydrolase family 43 beta-xylosidase from Geobacillus thermoleovorans IT-08 · PMID 18815904 · 6 records
• Purification and characterization of a hydroxamic acid glucoside beta-glucosidase from wheat (Triticum aestivum L.) seedlings · PMID 10750901 · 9 records
• Purification and Characterization of a Malate:Quinone Oxidoreductase from Pseudomonas taetrolens Capable of Producing Valuable Lactobionic Acid · PMID 33166455 · 4 records
• Purification and characterization of a monomeric isocitrate dehydrogenase with dual coenzyme specificity from the photosynthetic bacterium Rhodomicrobium vannielii · PMID 1935983 · 8 records
• Purification and characterization of a NADPH-dependent aldehyde reductase from mung bean that detoxifies eutypine, a toxin from eutypa lata1 · PMID 9952458 · 24 records
• Purification and characterization of a new human prostatic acid phosphatase isoenzyme · PMID 6404297 · 12 records
• Purification and characterization of a novel (R)-hydroxynitrile lyase from Eriobotrya japonica (Loquat) · PMID 18540101 · 9 records
• Purification and characterization of a novel carbaryl hydrolase from Aspergillus niger PY168 · PMID 14612234 · 11 records
• Purification and characterization of a novel dimeric 20 alpha-hydroxysteroid dehydrogenase from Tetrahymena pyriformis · PMID 8280099 · 18 records
• Purification and characterization of a novel fungal alpha-glucosidase from Mortierella alliacea with high starch-hydrolytic activity · PMID 12506981 · 6 records
• Purification and characterization of a novel NADP-dependent branched-chain alcohol dehydrogenase from Saccharomyces cerevisiae · PMID 9327572 · 19 records
• Purification and characterization of a novel NADPH(NADH)-dependent glyoxylate reductase from spinach leaves. Comparison of immunological properties of leaf glyoxylate reductase and hydroxypyruvate… · PMID 3548703 · 4 records
• Purification and characterization of a novel phloretin-2'-O-glycosyltransferase favoring phloridzin biosynthesis · PMID 27731384 · 14 records
• Purification and characterization of a novel pyrazole-sensitive carbonyl reductase in guinea pig lung · PMID 6753749 · 21 records
• Purification and characterization of a novel recombinant highly enantioselective short-chain NAD(H)-dependent alcohol dehydrogenase from Thermus thermophilus · PMID 18456852 · 15 records
• Purification and characterization of a phytase from Klebsiella terrigena · PMID 9169005 · 13 records
• Purification and characterization of a purple acid phosphatase from rat spleen · PMID 6706919 · 18 records
• Purification and characterization of a pyranose oxidase from the basidiomycete Peniophora gigantea and chemical analyses of its reaction products · PMID 8319689 · 4 records
• Purification and characterization of a recombinant laccase-like multi-copper oxidase from Paenibacillus glucanolyticus SLM1 · PMID 27451019 · 3 records
• Purification and characterization of a reduced nicotinamide adenine dinucleotide phosphate-linked aldehyde reductase from brain · PMID 4393513 · 7 records
• Purification and characterization of a tartrate-resistant acid phosphatase from human osteoclastomas · PMID 2775236 · 16 records
• Purification and characterization of a thermostable carboxylesterase from the thermoacidophilic eubacterium Bacillus acidocaldarius · PMID 8181479 · 20 records
• Purification and characterization of a two-component monooxygenase that hydroxylates nitrilotriacetate from "Chelatobacter" strain ATCC 29600 · PMID 1735711 · 4 records
• Purification and characterization of acid phosphatase from yellow lupin (Lupinus luteus) seeds · PMID 9300805 · 20 records
• Purification and characterization of adenosine diphosphate glucose pyrophosphorylase from maize/potato mosaics · PMID 15951484 · 18 records
• Purification and characterization of Ak.1 protease, a thermostable subtilisin with a disulphide bond in the substrate-binding cleft · PMID 10926860 · 21 records
• Purification and characterization of alanine dehydrogenase from a cyanobacterium, Phormidium lapideum · PMID 7896761 · 6 records
• Purification and characterization of alpha-glucosidase I from Japanese honeybee (Apis cerana japonica) and molecular cloning of its cDNA · PMID 17151473 · 11 records
• Purification and characterization of an activator protein for methanol dehydrogenase from thermotolerant Bacillus spp · PMID 1995643 · 8 records
• Purification and characterization of an alcohol dehydrogenase from the Antarctic psychrophile Moraxella sp. TAE123 · PMID 9660191 · 7 records
• Purification and characterization of an alpha-glucosidase from germinating millet seeds · PMID 15845403 · 12 records
• Purification and characterization of aromatic amine dehydrogenase from Alcaligenes xylosoxidans · PMID 15388968 · 4 records
• Purification and characterization of banana fruit acid phosphatase · PMID 11800388 · 11 records
• Purification and characterization of barley dipeptidyl peptidase IV · PMID 10677435 · 18 records
• Purification and characterization of benzoate-para-hydroxylase, a cytochrome P450 (CYP53A1), from Aspergillus niger · PMID 11594739 · 9 records
• Purification and characterization of benzyl alcohol- and benzaldehyde- dehydrogenase from Pseudomonas putida CSV86 · PMID 21448720 · 40 records
• Purification and characterization of bifunctional alginate lyase from Alteromonas sp. strain no. 272 and its action on saturated oligomeric substrates · PMID 11272816 · 12 records
• Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from rat liver · PMID 624713 · 12 records
• Purification and characterization of cellobiose dehydrogenase from the plant pathogen Sclerotium (Athelia) rolfsii · PMID 11282631 · 28 records
• Purification and characterization of cellobiose dehydrogenase, a novel extracellular hemoflavoenzyme from the white-rot fungus Phanerochaete chrysosporium · PMID 8434950 · 10 records
• Purification and characterization of cytosol phosphoenolpyruvate carboxykinase from bullfrog (Rana catesbeiana) liver · PMID 314446 · 15 records
• Purification and characterization of cytosolic pyruvate kinase from Brassica napus (rapeseed) suspension cell cultures: implications for the integration of glycolysis with nitrogen assimilation · PMID 10880971 · 11 records
• Purification and characterization of D-glyceraldehyde-3-phosphate dehydrogenase from the thermophilic archaebacterium Methanothermus fervidus · PMID 3569291 · 6 records
• Purification and characterization of delta 4-3-ketosteroid 5 beta-reductase · PMID 6736016 · 8 records
• Purification and characterization of dimeric dihydrodiol dehydrogenase from dog liver · PMID 7852295 · 28 records
• Purification and characterization of enzymes exhibiting beta-D-xylosidase activities in stem tissues of Arabidopsis · PMID 15181203 · 4 records
• Purification and characterization of extracellular alpha-amylase and glucoamylase from the yeast Candida antarctica CBS 6678 · PMID 3106037 · 24 records
• Purification and characterization of fumarase from Corynebacterium glutamicum · PMID 16717409 · 12 records
• Purification and characterization of gamma-glutamylcysteine synthetase from Ascaris suum · PMID 8538700 · 4 records
• Purification and characterization of glpQ-encoded glycerophosphodiester phosphodiesterase from Escherichia coli K-12 · PMID 2829735 · 8 records
• Purification and characterization of glucose-6-phosphate dehydrogenase from Aspergillus niger and Aspergillus nidulans · PMID 8277259 · 4 records
• Purification and characterization of glycerophosphate acyltransferase from rat liver mitochondria · PMID 7961630 · 15 records
• Purification and characterization of guinea pig liver morphine 6-dehydrogenase · PMID 2580834 · 14 records
• Purification and characterization of heterologously expressed nitrilases from filamentous fungi · PMID 21892598 · 19 records
• Purification and characterization of human liver "high Km" aldehyde dehydrogenase and its identification as glutamic gamma-semialdehyde dehydrogenase · PMID 3944130 · 25 records
• Purification and characterization of human liver sorbitol dehydrogenase · PMID 3365415 · 9 records
• Purification and characterization of human prolyl dipeptidase DPP8 in Sf9 insect cells · PMID 15039077 · 6 records
• Purification and characterization of human testis aldose and aldehyde reductase · PMID 1901806 · 12 records
• Purification and characterization of human-brain aldose reductase · PMID 6814912 · 16 records
• Purification and characterization of hydroxypyruvate reductase from a serine-producing methylotroph, Hyphomicrobium methylovorum GM2 · PMID 2114287 · 3 records
• Purification and characterization of isocitrate dehydrogenase from a hyperthermophilic archaebacterium, Caldococcus noboribetus · PMID 9252109 · 4 records
• Purification and Characterization of Latent Polyphenol Oxidase from Apricot (Prunus armeniaca L.) · PMID 28812349 · 4 records
• Purification and characterization of malate dehydrogenase from Corynebacterium glutamicum · PMID 16233457 · 10 records
• Purification and characterization of malate dehydrogenase from the syntrophic propionate-oxidizing bacterium strain MPOB · PMID 8900056 · 4 records
• Purification and characterization of methylmalonate-semialdehyde dehydrogenase from rat liver. Identity to malonate-semialdehyde dehydrogenase · PMID 2768248 · 4 records
• Purification and characterization of NADP+-dependent 3 alpha-hydroxysteroid dehydrogenase from mouse liver cytosol · PMID 3170514 · 34 records
• Purification and characterization of PBP4a, a new low-molecular-weight penicillin-binding protein from Bacillus subtilis · PMID 11160090 · 7 records
• Purification and characterization of phenylalanine 4-monooxygenase from rat liver · PMID 7407194 · 11 records
• Purification and characterization of pranlukast hydrolase from rat liver microsomes: the hydrolase is identical to carboxylesterase pI 6.2 · PMID 9013810 · 23 records
• Purification and characterization of prostaglandin F synthase from bovine liver · PMID 1605628 · 25 records
• Purification and characterization of pyranose oxidase from the white rot fungus Trametes multicolor · PMID 11472941 · 24 records
• Purification and characterization of pyrophosphate- and ATP-dependent phosphofructokinases from banana fruit · PMID 12721855 · 16 records
• Purification and characterization of recombinant human liver glycolate oxidase · PMID 17669354 · 9 records
• Purification and characterization of recombinant human neutrophil leukotriene B4 omega-hydroxylase (cytochrome P450 4F3) · PMID 9675028 · 11 records
• Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the… · PMID 3968063 · 22 records
• Purification and characterization of the alanine aminotransferase from the hyperthermophilic Archaeon pyrococcus furiosus and its role in alanine production · PMID 10762259 · 8 records
• Purification and characterization of the constitutive form of laccase from the basidiomycete Coriolus hirsutus and effect of inducers on laccase synthesis · PMID 9693088 · 6 records
• Purification and characterization of the first archaeal aconitase from the thermoacidophilic Sulfolobus acidocaldarius · PMID 11248696 · 5 records
• Purification and characterization of the first archaeal glutamate decarboxylase from Pyrococcus horikoshii · PMID 19129626 · 4 records
• Purification and characterization of the multiple forms of aldehyde reductase in ox kidney · PMID 6753832 · 27 records
• Purification and characterization of the oxygen-sensitive 4-hydroxybutanoate dehydrogenase from Clostridium kluyveri · PMID 7606170 · 5 records
• Purification and characterization of the VanB ligase associated with type B vancomycin resistance in Enterococcus faecalis V583 · PMID 7957913 · 8 records
• Purification and characterization of three phytases from germinated lupine seeds (Lupinus albus var. amiga) · PMID 12405788 · 45 records
• Purification and characterization of two alpha-galactosidases associated with catabolism of guar gum and other alpha-galactosides by Bacteroides ovatus · PMID 2981815 · 10 records
• Purification and characterization of two enantioselective alpha-ketoglutarate-dependent dioxygenases, RdpA and SdpA, from Sphingomonas herbicidovorans MH · PMID 16820480 · 9 records
• Purification and characterization of two isozymes of 3-phosphoglycerate kinase from the mouse · PMID 23844 · 24 records
• Purification and characterization of two reversible and ADP-dependent acetyl coenzyme A synthetases from the hyperthermophilic archaeon Pyrococcus furiosus · PMID 8830684 · 23 records
• Purification and characterization of two secreted purple acid phosphatase isozymes from phosphate-starved tomato (Lycopersicon esculentum) cell cultures · PMID 12473124 · 21 records
• Purification and characterization of xylitol dehydrogenase with l-arabitol dehydrogenase activity from the newly isolated pentose-fermenting yeast Meyerozyma caribbica 5XY2 · PMID 27506274 · 9 records
• Purification and characterizations of beta-Ketoacyl-[acyl-carrier-protein] reductase, beta-hydroxyacyl-[acyl-carrier-protein] dehydrase, and enoyl-[acyl-carrier-protein] reductase from Spinacia… · PMID 6756317 · 17 records
• Purification and cloning of chloroplast 6-phosphogluconate dehydrogenase from spinach. Cyanobacterial genes for chloroplast and cytosolic isoenzymes encoded in eukaryotic chromosomes · PMID 11322889 · 2 records
• Purification and detailed study of two clinically different human glucose 6-phosphate dehydrogenase variants, G6PD(Plymouth) and G6PD(Mahidol): Evidence for defective protein folding as the basis of… · PMID 17959407 · 6 records
• Purification and enzymatic properties of glyoxylate reductase II from baker's yeast · PMID 6993451 · 4 records
• Purification and Initial Characterization of 3-Hydroxybenzoate 6-Hydroxylase From a Halophilic Martelella Strain AD-3 · PMID 30034371 · 12 records
• Purification and kinetic analysis of the two recombinant arogenate dehydrogenase isoforms of Arabidopsis thaliana · PMID 12354106 · 5 records
• Purification and kinetic characterization of mannitol-1-phosphate dehydrogenase from Aspergillus niger · PMID 7030216 · 17 records
• Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-kappa B1 p105 · PMID 16087150 · 12 records
• Purification and kinetic study of glyoxalase-I from rat liver, erythrocytes, brain and kidney · PMID 953039 · 11 records
• Purification and molecular characterization of the NAD(+)-dependent acetaldehyde/alcohol dehydrogenase from Entamoeba histolytica · PMID 7980441 · 6 records
• Purification and partial characterization of a novel thermophilic carboxylesterase with high mesophilic specific activity · PMID 7576531 · 13 records
• Purification and partial characterization of an aldo-keto reductase from Saccharomyces cerevisiae · PMID 7747971 · 8 records
• Purification and partial characterization of camel anionic chymotrypsin · PMID 9434749 · 10 records
• Purification and partial characterization of the pancreatic proteolytic enzymes trypsin, chymotrypsin, and elastase from the chicken · PMID 10480246 · 6 records
• Purification and preliminary characterization of a serine hydrolase involved in the microbial degradation of polychlorinated biphenyls · PMID 9722515 · 13 records
• Purification and properties of 2,3-bisphosphoglycerate phosphatase-mutase from erythrocytes of day-old chicks · PMID 199431 · 2 records
• Purification and properties of 4-hydroxybenzoate 1-hydroxylase (decarboxylating), a novel flavin adenine dinucleotide-dependent monooxygenase from Candida parapsilosis CBS604 · PMID 9352916 · 17 records
• Purification and properties of a beta-galactosidase with potential application as a digestive supplement · PMID 17625262 · 3 records
• Purification and properties of a novel arylmalonate decarboxylase from Alcaligenes bronchisepticus KU 1201 · PMID 1459132 · 14 records
• Purification and properties of a novel enzyme, maltooligosyl trehalose synthase, from Arthrobacter sp. Q36 · PMID 8611744 · 4 records
• Purification and properties of a phenol sulphotransferase from Euglena using L-tyrosine as substrate · PMID 8129730 · 17 records
• Purification and properties of alanopine dehydrogenase from the adductor muscle of the oyster, Crassostrea gigas (Mollusca, Bivalvia) · PMID 7238503 · 12 records
• Purification and properties of aldehyde reductases from human placenta · PMID 3890957 · 11 records
• Purification and properties of an extracellular glucoamylase from a diastatic strain of Saccharomyces cerevisiae · PMID 3124820 · 11 records
• Purification and Properties of an NADPH-Aldose Reductase (Aldehyde Reductase) from Euonymus japonica Leaves · PMID 16664750 · 22 records
• Purification and properties of an NADPH-linked aldehyde reductase from rat kidney · PMID 6416297 · 25 records
• Purification and properties of bovine liver lysosomal adenosine 5'-phosphosulphate sulphohydrolase. A non-specific enzyme with pyrophosphatase and phosphodiesterase activities · PMID 214136 · 5 records
• Purification and properties of bovine liver plasma membrane 5' nucleotidase · PMID 6317380 · 10 records
• Purification and properties of carnitine acetyltransferase from human liver · PMID 2351134 · 15 records
• Purification and properties of carnitine acetyltransferase from rat liver · PMID 6404901 · 20 records
• Purification and properties of cytosolic and mitochondrial malic enzyme isolated from human brain · PMID 7757881 · 6 records
• Purification and properties of diphosphopyridine nuleotide-linked isocitrate dehydrogenase of mammalian liver · PMID 4387006 · 21 records
• Purification and properties of F420- and NADP(+)-dependent alcohol dehydrogenases of Methanogenium liminatans and Methanobacterium palustre, specific for secondary alcohols · PMID 1879431 · 30 records
• Purification and Properties of Flavin- and Molybdenum-Containing Aldehyde Oxidase from Coleoptiles of Maize · PMID 12226218 · 12 records
• Purification and Properties of Fructokinase from Developing Tubers of Potato (Solanum tuberosum L.) · PMID 16652943 · 15 records
• Purification and properties of gentamicin acetyltransferase I · PMID 764855 · 5 records
• Purification and properties of glycerol-3-phosphate dehydrogenase from the liver of the hibernating ground squirrel, Urocitellus richardsonii · PMID 27521690 · 21 records
• Purification and Properties of Glycine Oxidase from Pseudomonas putida KT2440 · PMID 26875494 · 4 records
• Purification and properties of histidinol dehydrogenases from psychrophilic, mesophilic and thermophilic bacilli · PMID 921748 · 10 records
• Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene · PMID 8662720 · 27 records
• Purification and properties of human D-3-hydroxyacyl-CoA dehydratase: medium-chain enoyl-CoA hydratase is D-3-hydroxyacyl-CoA dehydratase · PMID 8902629 · 19 records
• Purification and properties of human intestine alanine aminopeptidase · PMID 6103715 · 15 records
• Purification and properties of human liver aldehyde reductases · PMID 6753936 · 17 records
• Purification and properties of inosine-guanosine phosphorylase from Escherichia coli K-12 · PMID 3042752 · 13 records
• Purification and properties of membrane-bound aminopeptidase P from rat lung · PMID 7669781 · 12 records
• Purification and properties of methylmalonyl coenzyme A mutase from human liver · PMID 6124211 · 2 records
• Purification and properties of mitochondrial and peroxisomal 3-hydroxyacyl-CoA dehydrogenase from rat liver · PMID 6773478 · 17 records
• Purification and properties of mitochondrial phosphoenolpyruvate carboxykinase from liver of Squalus acanthias · PMID 2369129 · 13 records
• Purification and properties of N5-methyltetrahydromethanopterin:coenzyme M methyltransferase from Methanobacterium thermoautotrophicum · PMID 8477726 · 2 records
• Purification and properties of NADPH-dependent aldehyde reductase from human liver · PMID 16919 · 17 records
• Purification and properties of ornithine carbamoyltransferase from loggerhead turtle liver · PMID 12108925 · 20 records
• Purification and properties of prostaglandin 9-ketoreductase from pig and human kidney. Identity with human carbonyl reductase · PMID 1597188 · 5 records
• Purification and properties of short chain acyl-CoA, medium chain acyl-CoA, and isovaleryl-CoA dehydrogenases from human liver · PMID 3597357 · 21 records
• Purification and properties of soluble and bound gamma-glutamyltransferases from radish cotyledon · PMID 16495652 · 20 records
• Purification and properties of sorbitol dehydrogenase from mouse liver · PMID 6852349 · 4 records
• Purification and properties of the aromatic amino acid aminotransferase from gramicidin S-producing Bacillus brevis · PMID 2440856 · 18 records
• Purification and properties of the L-amino acid oxidase from Malayan pit viper (Calloselasma rhodostoma) venom · PMID 8080286 · 15 records
• Purification and properties of the L-amino acid oxidase from monocellate cobra (Naja naja kaouthia) venom · PMID 1612186 · 18 records
• Purification and properties of the mannokinase from Escherichia coli · PMID 4557975 · 12 records
• Purification and properties of thiol beta-lactamase. A mutant of pBR322 beta-lactamase in which the active site serine has been replaced with cysteine · PMID 6425288 · 17 records
• Purification and properties of three NAD(P)+ isozymes of L-glutamate dehydrogenase of Chlamydomonas reinhardtii · PMID 1540636 · 21 records
• Purification and Some Properties of a Protease from the Sarcocarp of Musk Melon Fruit · PMID 27396886 · 8 records
• Purification and some properties of aldehyde reductases from pig liver · PMID 6989609 · 17 records
• Purification and some properties of cytosol 5'-nucleotidase from rat liver · PMID 6260203 · 14 records
• Purification and some properties of sarcosine oxidase from Corynebacterium sp. U-96 · PMID 7240129 · 9 records
• Purification and some properties of wild-type and N-terminal-truncated ethanolamine ammonia-lyase of Escherichia coli · PMID 19762342 · 8 records
• Purification and steady-state kinetic characterization of human liver beta 3 beta 3 alcohol dehydrogenase · PMID 2819035 · 9 records
• Purification and substrate specificity of honeybee, Apis mellifera L., alpha-glucosidase III · PMID 11515546 · 13 records
• Purification of 2-oxoaldehyde dehydrogenase and its dependence on unusual amines · PMID 998 · 12 records
• Purification of acetaldehyde dehydrogenase and alcohol dehydrogenases from Thermoanaerobacter ethanolicus 39E and characterization of the secondary-alcohol dehydrogenase (2 degrees Adh) as a… · PMID 8068002 · 31 records
• Purification of an isoflavonoid 7-O-beta-apiosyl-glucoside beta-glycosidase and its substrates from Dalbergia nigrescens Kurz · PMID 16098548 · 6 records
• Purification of and kinetic studies on a cloned protoporphyrinogen oxidase from the aerobic bacterium Bacillus subtilis · PMID 9784236 · 3 records
• Purification of polyphosphate and ATP glucose phosphotransferase from Mycobacterium tuberculosis H37Ra: evidence that poly(P) and ATP glucokinase activities are catalyzed by the same enzyme · PMID 8381043 · 6 records
• Purification of the 45 kDa, membrane bound NADH dehydrogenase of Escherichia coli (NDH-2) and analysis of its interaction with ubiquinone analogues · PMID 10664466 · 6 records
• Purification of the NADPH:5 alpha-dihydroprogesterone 3 alpha-hydroxysteroid oxidoreductase from female rat pituitary cytosol · PMID 2268552 · 5 records
• Purification of the recombinant human serotonin N-acetyltransferase (EC 2.3.1.87): further characterization of and comparison with AANAT from other species · PMID 15477086 · 41 records
• Purification, catalytic properties and thermostability of 3-isopropylmalate dehydrogenase from Escherichia coli · PMID 9003442 · 8 records
• Purification, cDNA cloning and expression of 15-oxoprostaglandin 13-reductase from pig lung · PMID 9461497 · 9 records
• Purification, characterization and amino acid sequence of a novel enzyme, D-threo-3-hydroxyaspartate dehydratase, from Delftia sp. HT23 · PMID 20843822 · 5 records
• Purification, characterization and biological activities of the L-amino acid oxidase from Bungarus fasciatus snake venom · PMID 19393676 · 14 records
• Purification, characterization and catalytic properties of human sterol 8-isomerase · PMID 12133002 · 4 records
• Purification, characterization and cDNA cloning of a trypsin from the hepatopancreas of snakehead (Channa argus) · PMID 22155550 · 5 records
• Purification, characterization and crystallization of thermostable anthranilate phosphoribosyltransferase from Sulfolobus solfataricus · PMID 11298741 · 6 records
• Purification, characterization and partial amino acid sequencing of two new aspartic proteinases from fresh flowers of Cynara cardunculus L · PMID 8654427 · 4 records
• Purification, characterization and substrate specificity of a trypsin from the Amazonian fish tambaqui (Colossoma macropomum) · PMID 20438707 · 23 records
• Purification, characterization cloning, and sequencing of metalloendopeptidase from Streptomyces septatus TH-2 · PMID 15639229 · 1 record
• Purification, characterization, and application of a high activity 3-ketosteroid-Δ¹-dehydrogenase from Mycobacterium neoaurum DSM 1381 · PMID 31289904 · 9 records
• Purification, characterization, and cDNA cloning of opine dehydrogenases from the polychaete rockworm Marphysa sanguinea · PMID 17350870 · 58 records
• Purification, characterization, and chemical modification of manganese peroxidase from Bjerkandera adusta UAMH 8258 · PMID 12070683 · 20 records
• Purification, characterization, and gene cloning of cis,cis-muconate cycloisomerase from benzamide-assimilating Arthrobacter sp. BA-5-17 · PMID 14769475 · 5 records
• Purification, characterization, and mechanism of a flavin mononucleotide-dependent 2-nitropropane dioxygenase from Neurospora crassa · PMID 9501443 · 6 records
• Purification, characterization, and metabolic function of tungsten-containing aldehyde ferredoxin oxidoreductase from the hyperthermophilic and proteolytic archaeon Thermococcus strain ES-1 · PMID 7642503 · 15 records
• Purification, characterization, and molecular cloning of a pyranose oxidase from the fruit body of the basidiomycete, Tricholoma matsutake · PMID 14730138 · 11 records
• Purification, characterization, and molecular cloning of tyrosinase from Pholiota nameko · PMID 17617709 · 9 records
• Purification, characterization, and overexpression of psychrophilic and thermolabile malate dehydrogenase of a novel antarctic psychrotolerant, Flavobacterium frigidimaris KUC-1 · PMID 16306697 · 8 records
• Purification, characterization, and sequence analysis of a potential virulence factor from Porphyromonas gingivalis, peptidylarginine deiminase · PMID 10377098 · 6 records
• Purification, characterization, and substrate specificity of two 2,3-dihydroxybiphenyl 1,2-dioxygenase from Rhodococcus sp. R04, showing their distinct stability at various temperature · PMID 18585431 · 17 records
• Purification, characterization, cloning, and expression of a glutamic acid-specific protease from Bacillus licheniformis ATCC 14580 · PMID 1429718 · 10 records
• Purification, cloning, and heterologous expression of a catalytically efficient flavonol 3-O-galactosyltransferase expressed in the male gametophyte of Petunia hybrida · PMID 10567367 · 8 records
• Purification, cloning, and properties of an acyltransferase controlling shikimate and quinate ester intermediates in phenylpropanoid metabolism · PMID 12381722 · 7 records
• Purification, immobilization, and biochemical characterization of l-arginine deiminase from thermophilic Aspergillus fumigatus KJ434941: anticancer activity in vitro · PMID 25582958 · 9 records
• Purification, kinetic characterization, and molecular cloning of a novel enzyme ecdysteroid-phosphate phosphatase · PMID 12721294 · 7 records
• Purification, molecular cloning, and catalytic activity of Schizosaccharomyces pombe pyridoxal reductase. A possible additional family in the aldo-keto reductase superfamily · PMID 10438489 · 8 records
• Purification, molecular cloning, and characterization of pyridoxine 4-oxidase from Microbacterium luteolum · PMID 12092811 · 4 records
• Purification, molecular, and catalytic properties of pyruvate phosphate dikinase from the maize leaf · PMID 4719122 · 5 records
• Purification, properties, and characterization of recombinant Streptomyces sp. strain C5 DoxA, a cytochrome P-450 catalyzing multiple steps in doxorubicin biosynthesis · PMID 9864343 · 4 records
• Purification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2 · PMID 11940569 · 9 records
• Purine nucleoside phosphorylase from bovine lens: purification and properties · PMID 1445943 · 13 records
• Purine nucleoside phosphorylase from Escherichia coli and Salmonella typhimurium. Purification and some properties · PMID 235429 · 15 records
• Purine nucleoside phosphorylase. 1. Structure-function studies · PMID 9305962 · 45 records
• Puromycin-sensitive alanyl aminopeptidase from human liver cytosol: purification and characterization · PMID 10978616 · 5 records
• Purple acid phosphatase in the walls of tobacco cells · PMID 18762304 · 8 records
• Putative functional role for the invariant aspartate 263 residue of Rhodospirillum rubrum Rubisco · PMID 19231887 · 12 records
• Putative reaction mechanism of heterologously expressed octopine dehydrogenase from the great scallop, Pecten maximus (L) · PMID 18028427 · 19 records
• Putrescine N-methyltransferases--a structure-function analysis · PMID 17221359 · 9 records
• Pycnoporus cinnabarinus glyoxal oxidases display differential catalytic efficiencies on 5-hydroxymethylfurfural and its oxidized derivatives · PMID 30984409 · 13 records
• Pyranose 2-oxidase from Phanerochaete chrysosporium--expression in E. coli and biochemical characterization · PMID 19501263 · 17 records
• Pyranose 2-oxidase from Phanerochaete chrysosporium--further biochemical characterisation · PMID 9210340 · 33 records
• Pyranose Dehydrogenase from Agaricus campestris and Agaricus xanthoderma: Characterization and Applications in Carbohydrate Conversions · PMID 24970179 · 16 records
• Pyridine Nucleotide Coenzyme Specificity of p-Hydroxybenzoate Hydroxylase and Related Flavoprotein Monooxygenases · PMID 30631308 · 14 records
• Pyridine nucleotide complexes with Bacillus anthracis coenzyme A-disulfide reductase: a structural analysis of dual NAD(P)H specificity · PMID 18399646 · 8 records
• Pyrimethamine-resistant dihydrofolate reductase enzymes of Plasmodium falciparum are not enzymatically compromised in vitro · PMID 17451822 · 8 records
• Pyrimidine nucleoside monophosphate kinase from rat liver and rat Novikoff ascites hepatoma (EC 2.7.4.14) · PMID 211381 · 18 records
• Pyroglutamyl aminopeptidase I, as a drug metabolizing enzyme, recognizes xenobiotic substrates containing L-2-oxothiazolidine-4-carboxylic acid · PMID 14709911 · 20 records
• Pyroglutamyl peptidase type I from Trypanosoma brucei: a new virulence factor from African trypanosomes that de-blocks regulatory peptides in the plasma of infected hosts · PMID 16248854 · 8 records
• Pyrroloquinoline Quinone Ethanol Dehydrogenase in Methylobacterium extorquens AM1 Extends Lanthanide-Dependent Metabolism to Multicarbon Substrates · PMID 27573017 · 4 records
• Pyruvate kinase directly generates GTP in glycolysis, supporting growth and contributing to guanosine toxicity · PMID 39998177 · 4 records
• Pyruvate kinase of Trypanosoma brucei: overexpression, purification, and functional characterization of wild-type and mutated enzyme · PMID 9693062 · 23 records
• Quantifying cathepsin S activity in antigen presenting cells using a novel specific substrate · PMID 18957408 · 50 records
• Quantifying the Characteristic Turnover Frequency of an Individual Redox Enzyme via Real-Time Electrical Transduction of Catalytic Events in a Label-Free Single-Protein Junction · PMID 42584624 · 6 records
• Quantitative functional characterization of conserved molecular interactions in the active site of mannitol 2-dehydrogenase · PMID 25752240 · 31 records
• Quaternary organization in a bifunctional prokaryotic FAD synthetase: Involvement of an arginine at its adenylyltransferase module on the riboflavin kinase activity · PMID 25801930 · 11 records
• Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes · PMID 18073106 · 14 records
• Quercetin production from rutin by a thermostable β-rutinosidase from Pyrococcus furiosus · PMID 22052256 · 3 records
• Quinohaemoprotein alcohol dehydrogenase apoenzyme from Pseudomonas testosteroni · PMID 3521592 · 12 records
• Quinone reductase reaction catalyzed by Streptococcus faecalis NADH peroxidase · PMID 7756294 · 16 records
• R-hydroxynitrile lyase from the cyanogenic millipede, Chamberlinius hualienensis-A new entry to the carrier protein family Lipocalines · PMID 32679618 · 10 records
• Random mutagenesis improves the low-temperature activity of the tetrameric 3-isopropylmalate dehydrogenase from the hyperthermophile Sulfolobus tokodaii · PMID 18854331 · 36 records
• Random mutagenesis into the conserved Gly154 of subtilisin E: isolation and characterization of the revertant enzymes · PMID 9930669 · 16 records
• Random mutagenesis of pullulanase from Klebsiella aerogenes for studies of the structure and function of the enzyme · PMID 7706211 · 8 records
• Rapid and flexible biochemical assays for evaluating 4'-phosphopantetheinyl transferase activity · PMID 21466506 · 20 records
• Rapid evolution of beta-glucuronidase specificity by saturation mutagenesis of an active site loop · PMID 15069062 · 10 records
• Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme · PMID 14973125 · 31 records
• Rapid simultaneous determination of metabolic clearance of multiple compounds catalyzed in vitro by recombinant human UDP-glucuronosyltransferases · PMID 15866534 · 15 records
• Rat aldose reductase-like protein (AKR1B14) efficiently reduces the lipid peroxidation product 4-oxo-2-nonenal · PMID 21048316 · 42 records
• Rat guanidinoacetate methyltransferase. Effect of site-directed alteration of an aspartic acid residue that is conserved across most mammalian S-adenosylmethionine-dependent methyltransferases · PMID 8119887 · 26 records
• Rat inositol 1,4,5-trisphosphate 3-kinase C is enzymatically specialized for basal cellular inositol trisphosphate phosphorylation and shuttles actively between nucleus and cytoplasm · PMID 12649294 · 10 records
• Rat intestinal brush border membrane dipeptidyl-aminopeptidase IV: kinetic properties and substrate specificities of the purified enzyme · PMID 6756314 · 13 records
• Rat kidney L-2-hydroxyacid oxidase. Structural and mechanistic comparison with flavocytochrome b2 from baker's yeast · PMID 3061453 · 21 records
• Rat liver constitutive and phenobarbital-inducible cytosolic aldehyde dehydrogenases are highly homologous proteins that function as distinct isozymes · PMID 10998257 · 7 records
• Rat liver omega-amidase. Purification and properties · PMID 5114531 · 20 records
• Rat NAD+-dependent 3alpha-hydroxysteroid dehydrogenase (AKR1C17): a member of the aldo-keto reductase family highly expressed in kidney cytosol · PMID 17475203 · 51 records
• Rate and Equilibrium Constants for an Enzyme Conformational Change during Catalysis by Orotidine 5'-Monophosphate Decarboxylase · PMID 26135041 · 9 records
• Rates of phosphorylation and dephosphorylation of phosphoglycerate mutase and bisphosphoglycerate synthase · PMID 8447 · 14 records
• Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis · PMID 26356484 · 9 records
• Rational conversion of substrate and product specificity in a Salvia monoterpene synthase: structural insights into the evolution of terpene synthase function · PMID 17557809 · 13 records
• Rational Design of Aspergillus awamori Glucoamylase for Activity Improvement · PMID 42776784 · 5 records
• Rational design of cholesterol oxidase for efficient bioresolution of cholestane skeleton substrates · PMID 29180806 · 18 records
• Rational design of Meso-2,3-butanediol dehydrogenase by molecular dynamics simulation and experimental evaluations · PMID 28875495 · 20 records
• Rational design of novel mutants of fungal 17beta-hydroxysteroid dehydrogenase · PMID 17196285 · 4 records
• Rational design of ornithine decarboxylase with high catalytic activity for the production of putrescine · PMID 24706212 · 13 records
• Rational design of stereoselectivity in the class II pyruvate aldolase BphI · PMID 22081904 · 24 records
• Rational design of substrate binding pockets in polyphosphate kinase for use in cost-effective ATP-dependent cascade reactions · PMID 28417169 · 4 records
• Rational design toward developing a more efficient laccase: Catalytic efficiency and selectivity · PMID 29425870 · 10 records
• Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification · PMID 24919140 · 3 records
• Rational engineering of 2-deoxyribose-5-phosphate aldolases for the biosynthesis of (R)-1,3-butanediol · PMID 31806708 · 11 records
• Rational Engineering of Cellobiose 2-Epimerase Through Flexible Loop Modulation and Structure-Guided Sequence Alignment for Enhanced Lactulose Synthesis · PMID 41750276 · 3 records
• Rational selection of ketopantoate hydroxymethyltransferase with low product feedback inhibition based on binding free energy calculation analysis · PMID 42429766 · 5 records
• Rational structural design for the dual enhancement of catalytic activity and thermal stability of hyaluronidase from Citrobacter portucalensis · PMID 42178561 · 13 records
• Re-evaluation of the C-Glucosyltransferase IroB Illuminates Its Ability to C-Glucosylate Non-native Triscatecholate Enterobactin Mimics · PMID 39718537 · 7 records
• Reaction coupling through interdomain contacts in imidazole glycerol phosphate synthase · PMID 16142895 · 25 records
• Reaction mechanism and structural model of ADP-forming Acetyl-CoA synthetase from the hyperthermophilic archaeon Pyrococcus furiosus: evidence for a second active site histidine residue · PMID 18372246 · 28 records
• Reaction mechanism of chalcone isomerase. pH dependence, diffusion control, and product binding differences · PMID 11698411 · 8 records
• Reaction mechanism of chitobiose phosphorylase from Vibrio proteolyticus: identification of family 36 glycosyltransferase in Vibrio · PMID 13678418 · 7 records
• Reaction mechanism of glutathione synthetase from Arabidopsis thaliana: site-directed mutagenesis of active site residues · PMID 17452339 · 50 records
• Reaction mechanism of phosphoglucosamine mutase from Escherichia coli · PMID 10231382 · 9 records
• Reaction Mechanism of Prephenate Dehydrogenase from the Alternative Tyrosine Biosynthesis Pathway in Plants · PMID 29601138 · 12 records
• Reaction mechanism of the heterotetrameric (alpha2beta2) E1 component of 2-oxo acid dehydrogenase multienzyme complexes · PMID 12795594 · 2 records
• Reaction mechanism of Zn2+-dependent d-serine dehydratase: role of a conserved tyrosine residue interacting with pyridine ring nitrogen of pyridoxal 5'-phosphate · PMID 24881047 · 6 records
• Reaction of dopa decarboxylase with L-aromatic amino acids under aerobic and anaerobic conditions · PMID 11085948 · 4 records
• Reaction of human chymase with reactive site variants of alpha 1-antichymotrypsin. Modulation of inhibitor versus substrate properties · PMID 8226889 · 3 records
• Reaction of human UMP-CMP kinase with natural and analog substrates · PMID 12694191 · 15 records
• Reaction of the molybdenum- and copper-containing carbon monoxide dehydrogenase from Oligotropha carboxydovorans with quinones · PMID 21275368 · 3 records
• Reactions of asparaginase II of Saccharomyces cerevisiae. A mechanistic analysis of hydrolysis and hydroxylaminolysis · PMID 6986375 · 21 records
• Reactions of Plasmodium falciparum Ferredoxin:NADP⁺ Oxidoreductase with Redox Cycling Xenobiotics: A Mechanistic Study · PMID 32370303 · 31 records
• Reactions of Plasmodium falciparum Type II NADH: Ubiquinone Oxidoreductase with Nonphysiological Quinoidal and Nitroaromatic Oxidants · PMID 40141152 · 33 records
• Reactive amino acid residues involved in glutamate-binding of human glutamate dehydrogenase isozymes · PMID 15194228 · 22 records
• Reactivity and metal-dependent stereospecificity of the phosphorothioate analogs of ADP and ATP and reactivity of Cr(III)ATP in the 3-phosphoglycerate kinase reaction. Structure of the metal… · PMID 7045111 · 17 records
• Reactivity of horseradish peroxidase compound II toward substrates: kinetic evidence for a two-step mechanism · PMID 11052672 · 36 records
• Reappraisal of the regulation of lactococcal L-lactate dehydrogenase · PMID 15006814 · 24 records
• Reassessing the type I dehydroquinate dehydratase catalytic triad: kinetic and structural studies of Glu86 mutants · PMID 23341204 · 3 records
• Reassessment of effects on lignification and vascular development in the irx4 Arabidopsis mutant · PMID 16153410 · 6 records
• Reassessment of the reaction mechanism in the heme dioxygenases · PMID 19275153 · 5 records
• Recognition by tryptophanyl-tRNA synthetases of discriminator base on tRNATrp from three biological domains · PMID 11834741 · 37 records
• Recognition of nucleoside monophosphate substrates by Haemophilus influenzae class C acid phosphatase · PMID 20934434 · 4 records
• Recognition of tRNA^Ile with a UAU anticodon by isoleucyl-tRNA synthetase in lactic acid bacteria · PMID 35122395 · 14 records
• Recognition of unnatural base pairs by a eukaryotic DNA polymerase enables universal sequencing of an expanded genetic alphabet · PMID 41505089 · 6 records
• Recognition site for the side chain of 2-ketoacid substrate in d-lactate dehydrogenase · PMID 16428303 · 42 records
• Recognition, isolation, and characterization of rat liver D-methylmalonyl coenzyme A hydrolase · PMID 6885824 · 5 records
• Recombinant expression and biochemical characterization of the unique elongating beta-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using… · PMID 16467310 · 7 records
• Recombinant expression and characterization of the major beta-lactamase of Mycobacterium tuberculosis · PMID 9624479 · 24 records
• Recombinant expression and molecular insights into the catalytic mechanism of an NADPH-dependent conjugated polyketone reductase for the asymmetric synthesis of (R)-pantolactone · PMID 31000167 · 3 records
• Recombinant expression of an l-amino acid oxidase from the fungus Hebeloma cylindrosporum in Pichia pastoris including fermentation · PMID 32852125 · 12 records
• Recombinant expression, purification and biochemical characterization of kievitone hydratase from Nectria haematococca · PMID 29420618 · 1 record
• Recombinant expression, purification, and biochemical characterization of chondroitinase ABC II from Proteus vulgaris · PMID 18849565 · 7 records
• Recombinant expression, purification, and characterization of three isoenzymes of aspartate aminotransferase from Arabidopsis thaliana · PMID 9535706 · 12 records
• Recombinant heteromeric phenylalanine monooxygenase and the oxygenation of carbon and sulfur substrates · PMID 21401608 · 36 records
• Recombinant human DNA (cytosine-5) methyltransferase. III. Allosteric control, reaction order, and influence of plasmid topology and triplet repeat length on methylation of the fragile X CGG.CCG… · PMID 11359795 · 14 records
• Recombinant human liver medium-chain acyl-CoA dehydrogenase: purification, characterization, and the mechanism of interactions with functionally diverse C8-CoA molecules · PMID 7578106 · 19 records
• Recombinant production and characterisation of two related GH5 endo-β-1,4-mannanases from Aspergillus nidulans FGSC A4 showing distinctly different transglycosylation capacity · PMID 21867780 · 12 records
• Recombinant Production and Characterization of Six Ene-reductases from Penicillium steckii · PMID 40072226 · 12 records
• Recombinant rat nucleoside diphosphate kinase isoforms (alpha and beta): purification, properties and application to immunological detection of native isoforms in rat tissues · PMID 8142475 · 12 records
• Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases · PMID 28726643 · 16 records
• Reconstruction of an acetogenic 2,3-butanediol pathway involving a novel NADPH-dependent primary-secondary alcohol dehydrogenase · PMID 24657865 · 5 records
• Recovery of argininosuccinate lyase activity in duck delta1 crystallin · PMID 15966727 · 16 records
• Redefining the minimal substrate tolerance of mandelate racemase. Racemization of trifluorolactate · PMID 21894901 · 9 records
• Redesign of a New Manganese Peroxidase Highly Expressed in Pichia pastoris towards a Lignin-Degrading Versatile Peroxidase · PMID 30290081 · 23 records
• Redesign of carnitine acetyltransferase specificity by protein engineering · PMID 15155769 · 20 records
• Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities · PMID 24055536 · 12 records
• Redirecting catalysis from proteolysis to perhydrolysis in subtilisin Carlsberg · PMID 23835157 · 25 records
• Redox properties of flavocytochrome c3 from Shewanella frigidimarina NCIMB400 · PMID 10079073 · 12 records
• Redox-dependent changes in molecular properties of mitochondrial apoptosis-inducing factor · PMID 18167347 · 31 records
• Redox-dependent stability of the γ-glutamylcysteine synthetase enzyme of Escherichia coli: a novel means of redox regulation · PMID 23126248 · 21 records
• Redox-regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H-site flexibility · PMID 29732642 · 4 records
• Reduced catalytic activity of KPC β-lactamase can increase ceftazidime resistance · PMID 41946819 · 20 records
• Reductases for aromatic aldehydes and ketones from rabbit liver. Purification and characterization · PMID 7390984 · 60 records
• Reduction of benzoquinones to hydroquinones via spontaneous reaction with glutathione and enzymatic reaction by S-glutathionyl-hydroquinone reductases · PMID 22686328 · 20 records
• Reduction of lipid peroxidation products and advanced glycation end-product precursors by cyanobacterial aldo-keto reductase AKR3G1—a founding member of the AKR3G subfamily · PMID 25376835 · 27 records
• Reduction of quinones and nitroaromatic compounds by Escherichia coli nitroreductase A (NfsA): Characterization of kinetics and substrate specificity · PMID 27986535 · 31 records
• Reduction of S-nitrosoglutathione by human alcohol dehydrogenase 3 is an irreversible reaction as analysed by electrospray mass spectrometry · PMID 12631283 · 14 records
• Reduction of trioses by NADPH-dependent aldo-keto reductases. Aldose reductase, methylglyoxal, and diabetic complications · PMID 1537826 · 19 records
• Reduction precedes cytidylyl transfer without substrate channeling in distinct active sites of the bifunctional CDP-ribitol synthase from Haemophilus influenzae · PMID 11305920 · 21 records
• Reductive half-reaction of nitroalkane oxidase: effect of mutation of the active site aspartate to glutamate · PMID 12741843 · 4 records
• Reductive modification and nonreductive activation of purified spinach chloroplast NADP-dependent glyceraldehyde-3-phosphate dehydrogenase · PMID 8554310 · 13 records
• Refolding, characterization and crystal structure of (S)-malate dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix · PMID 19555779 · 15 records
• Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1A9 and UGT2B7 · PMID 25496264 · 28 records
• Regioselective monosulfation and disulfation of the phytoestrogens daidzein and genistein by human liver sulfotransferases · PMID 15499189 · 25 records
• Regioselectivity of taxoid-O-acetyltransferases: heterologous expression and characterization of a new taxadien-5alpha-ol-O-acetyltransferase · PMID 15369823 · 10 records
• Regiospecific O-methylation of naphthoic acids catalyzed by NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin · PMID 18387946 · 5 records
• Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets · PMID 19010784 · 2 records
• Regulation of Leishmania major PAS domain-containing phosphoglycerate kinase by cofactor Mg²⁺ ion at neutral pH · PMID 32196942 · 24 records
• Regulation of Microenvironments of Hydrogen-Bonded Organic Frameworks for Enhanced Enzyme Activity of Phosphotriesterase · PMID 42197205 · 6 records
• Regulation of photosynthetic GAPDH dissected by mutants · PMID 16055685 · 18 records
• Regulation of protein kinase D by multisite phosphorylation. Identification of phosphorylation sites by mass spectrometry and characterization by site-directed mutagenesis · PMID 10867018 · 41 records
• Regulation of S-adenosylhomocysteine hydrolase by lysine acetylation · PMID 25248746 · 12 records
• Regulation of the dauBAR operon and characterization of D-amino acid dehydrogenase DauA in arginine and lysine catabolism of Pseudomonas aeruginosa PAO1 · PMID 19850617 · 7 records
• Regulatory and functional diversity of methylmercaptopropionate coenzyme A ligases from the dimethylsulfoniopropionate demethylation pathway in Ruegeria pomeroyi DSS-3 and other proteobacteria · PMID 24443527 · 24 records
• Regulatory control of human cytosolic branched-chain aminotransferase by oxidation and S-glutathionylation and its interactions with redox sensitive neuronal proteins · PMID 18419134 · 32 records
• Regulatory mechanisms differ in UMP kinases from gram-negative and gram-positive bacteria · PMID 17210578 · 62 records
• Relationship of Catalysis and Active Site Loop Dynamics in the (βα)₈-Barrel Enzyme Indole-3-glycerol Phosphate Synthase · PMID 29498826 · 6 records
• Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells · PMID 8573067 · 18 records
• Relative catalytic efficiencies and transcript levels of three d- and two l-lactate dehydrogenases for optically pure d-lactate production in Sporolactobacillus inulinus · PMID 30066438 · 5 records
• Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues · PMID 34066758 · 8 records
• Relaxing the coenzyme specificity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design · PMID 20156491 · 6 records
• Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design · PMID 14529270 · 16 records
• Relevance of aromatic and polar amino acids in the specificity of Inulinase ISO3 from Kluyveromyces marxianus: A molecular dynamics approach with an experimental verification · PMID 37150366 · 19 records
• Relevant double mutations in bioengineered Streptomyces clavuligerus deacetoxycephalosporin C synthase result in higher binding specificities which improve penicillin bioconversion · PMID 18083859 · 34 records
• Remarkable transglycosylation activity of glycosynthase mutants of endo-D, an endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae · PMID 22318728 · 6 records
• Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency · PMID 32284326 · 17 records
• Remdesivir Is Effective in Combating COVID-19 because It Is a Better Substrate than ATP for the Viral RNA-Dependent RNA Polymerase · PMID 33283177 · 6 records
• Removal of substrate inhibition and increase in maximal velocity in the short chain dehydrogenase/reductase salutaridine reductase involved in morphine biosynthesis · PMID 19648114 · 32 records
• Removing allosteric feedback inhibition of tomato 4-coumarate:CoA ligase by directed evolution · PMID 21883557 · 11 records
• Repeated insertions at positions 261-280 in KPC-2 highlight a ceftazidime-avibactam resistance hotspot · PMID 42389611 · 6 records
• Replacement of Tyr50 stacked on the si-face of the isoalloxazine ring of the flavin adenine dinucleotide prosthetic group modulates Bacillus subtilis ferredoxin-NADP(+) oxidoreductase activity… · PMID 25698107 · 4 records
• Replacement set mutagenesis of the four phosphate-binding arginine residues of thymidylate synthase · PMID 10964985 · 105 records
• Replication past the butadiene diepoxide-derived DNA adduct S-[4-(N(6)-deoxyadenosinyl)-2,3-dihydroxybutyl]glutathione by DNA polymerases · PMID 23701509 · 36 records
• Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry · PMID 19397282 · 24 records
• Repurposing approved drugs targeting Leishmania infantum 5-Methylthioadenosine Phosphorylase as anti-leishmanial candidates · PMID 41909839 · 4 records
• Research Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia · PMID 26172259 · 4 records
• Reshaping the Binding Pocket of Cellobiose 2-Epimerase for Improved Substrate Affinity and Isomerization Activity for Enabling Green Synthesis of Lactulose · PMID 36475670 · 8 records
• Residue 234 is a master switch of the alternative-substrate activity profile of human and rodent theta class glutathione transferase T1-1 · PMID 20097269 · 8 records
• Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the… · PMID 19236001 · 28 records
• Residue Phe42 is critical for the catalytic activity of Escherichia coli major nitroreductase NfsA · PMID 23801116 · 20 records
• Residues Asn214, Gln211, Glu219 and Gln221 contained in the subfamily 3 catalytic signature of the isocitrate lyase from Pseudomonas aeruginosa are involved in its catalytic and thermal properties · PMID 23338961 · 5 records
• Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis · PMID 18434499 · 18 records
• Residues at the active site of the esterase 2 from Alicyclobacillus acidocaldarius involved in substrate specificity and catalytic activity at high temperature · PMID 11447219 · 43 records
• Residues essential for catalysis and stability of the active site of Escherichia coli adenylosuccinate synthetase as revealed by directed mutation and kinetics · PMID 9115248 · 18 records
• Residues His172 and Lys238 are Essential for the Catalytic Activity of the Maleylacetate Reductase from Sphingobium chlorophenolicum Strain L-1 · PMID 29273747 · 10 records
• Residues Lys-149 and Glu-153 switch the aminoacylation of tRNA(Trp) in Bacillus subtilis · PMID 15280378 · 40 records
• Residues specific for class III alcohol dehydrogenase. Site-directed mutagenesis of the human enzyme · PMID 7999766 · 68 records
• Resistance development in KPC-producing Klebsiella pneumoniae under ceftazidime/avibactam-meropenem pressure: KPC-2 Ω-loop mutations attenuate avibactam efficacy · PMID 42545018 · 16 records
• Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1 · PMID 26824416 · 11 records
• Resolution and partial characterization of two aldehyde reductases of mammalian liver · PMID 15991 · 24 records
• Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1 · PMID 28258219 · 6 records
• Resolving the roles of the Rhodobacter sphaeroides HemA and HemT 5-aminolevulinic acid synthases · PMID 30232811 · 8 records
• Restriction of substrate specificity of subtilisin E by introduction of a side chain into a conserved glycine residue · PMID 8898079 · 10 records
• Resurrection of an ancient inflammatory locus reveals switch to caspase-1 specificity on a caspase-4 scaffold · PMID 35427646 · 14 records
• Retention of NADPH-linked quinone reductase activity in an aldo-keto reductase following mutation of the catalytic tyrosine · PMID 9692994 · 13 records
• Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition · PMID 23220587 · 11 records
• Retinoids, omega-hydroxyfatty acids and cytotoxic aldehydes as physiological substrates, and H2-receptor antagonists as pharmacological inhibitors, of human class IV alcohol dehydrogenase · PMID 9600267 · 13 records
• Revealing two important tryptophan residues with completely different roles in a dye-decolorizing peroxidase from Irpex lacteus F17 · PMID 34059116 · 26 records
• Reversal of coenzyme specificity and improvement of catalytic efficiency of Pichia stipitis xylose reductase by rational site-directed mutagenesis · PMID 19330484 · 8 records
• Reversal of the deoxyhypusine synthesis reaction. Generation of spermidine or homospermidine from deoxyhypusine by deoxyhypusine synthase · PMID 12788913 · 10 records
• Reversal of the nucleotide specificity of ketol acid reductoisomerase by site-directed mutagenesis identifies the NADPH binding site · PMID 9015391 · 17 records
• Reverse and forward reactions of carbamyl phosphokinase from Streptococcus faecalis R. Participation of nucleotides and reaction mechanisms · PMID 6269635 · 14 records
• Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design · PMID 19894712 · 15 records
• Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins · PMID 26206330 · 5 records
• Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins · PMID 22307087 · 19 records
• Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase · PMID 19447118 · 36 records
• Reversing the substrate specificities of phenylalanine and tyrosine hydroxylase: aspartate 425 of tyrosine hydroxylase is essential for L-DOPA formation · PMID 10933781 · 20 records
• Revisiting the enzymatic kinetics of pepsin using isothermal titration calorimetry · PMID 30064809 · 6 records
• Revisiting the nucleotide and aminoglycoside substrate specificity of the bifunctional aminoglycoside acetyltransferase(6')-Ie/aminoglycoside phosphotransferase(2'')-Ia enzyme · PMID 23115238 · 9 records
• Revisiting the Roles of Catalytic Residues in Human Ornithine Transcarbamylase · PMID 38940639 · 22 records
• Reye-like syndrome resulting from novel missense mutations in mitochondrial medium- and short-chain l-3-hydroxy-acyl-CoA dehydrogenase · PMID 16725361 · 4 records
• Ribose 5-phosphate isomerase type B from Trypanosoma cruzi: kinetic properties and site-directed mutagenesis reveal information about the reaction mechanism · PMID 16981853 · 6 records
• Rice family GH1 glycoside hydrolases with beta-D-glucosidase and beta-D-mannosidase activities · PMID 19766588 · 27 records
• Ricin A-chain substrate specificity in RNA, DNA, and hybrid stem-loop structures · PMID 15109249 · 19 records
• Rifampin phosphotransferase is an unusual antibiotic resistance kinase · PMID 27103605 · 16 records
• RNAi suppression of Arogenate Dehydratase1 reveals that phenylalanine is synthesized predominantly via the arogenate pathway in petunia petals · PMID 20215586 · 5 records
• Role of 4-hydroxybutyrate-CoA synthetase in the CO2 fixation cycle in thermoacidophilic archaea · PMID 23258541 · 13 records
• Role of a conserved active site cation-pi interaction in Escherichia coli serine hydroxymethyltransferase · PMID 19883126 · 14 records
• Role of a conserved arginine in the mechanism of acetohydroxyacid synthase: catalysis of condensation with a specific ketoacid substrate · PMID 15044456 · 13 records
• Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5'-phosphate decarboxylase-catalyzed reactions · PMID 24053466 · 7 records
• Role of a highly conserved proline-126 in ThDP binding of Mycobacterium tuberculosis acetohydroxyacid synthase · PMID 23931689 · 4 records
• Role of a highly conserved YPITP motif in 2-oxoacid:ferredoxin oxidoreductase: heterologous expression of the gene from Sulfolobus sp.strain 7, and characterization of the recombinant and variant… · PMID 11683888 · 26 records
• Role of active site binding interactions in 4-chlorobenzoyl-coenzyme A dehalogenase catalysis · PMID 11747444 · 20 records
• Role of active site histidines in the two half-reactions of the aryl-alcohol oxidase catalytic cycle · PMID 22834786 · 5 records
• Role of active site loop in coenzyme binding and flavin reduction in cytochrome P450 reductase · PMID 27461959 · 14 records
• Role of active-site residues of dispersin B, a biofilm-releasing beta-hexosaminidase from a periodontal pathogen, in substrate hydrolysis · PMID 17949435 · 11 records
• Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity · PMID 14967036 · 31 records
• Role of Ambler Position 104 in Defining Substrate Specificity in the KPC Family of β-Lactamases · PMID 42047351 · 5 records
• Role of amino acid residues in the active site of rat liver mercaptopyruvate sulfurtransferase. CDNA cloning, overexpression, and site-directed mutagenesis · PMID 8910318 · 12 records
• Role of arginine 177 in the MnII binding site of manganese peroxidase. Studies with R177D, R177E, R177N, and R177Q mutants · PMID 11106414 · 8 records
• Role of arginine 285 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study · PMID 10821840 · 4 records
• Role of arginine 59 in the gamma-class carbonic anhydrases · PMID 11781108 · 34 records
• Role of arginines in coenzyme A binding and catalysis by the phosphotransacetylase from Methanosarcina thermophila · PMID 11418565 · 27 records
• Role of Asn-382 and Thr-383 in activation and inactivation of human prostaglandin H synthase cyclooxygenase catalysis · PMID 14625295 · 16 records
• Role of Asp104 in the SHV beta-lactamase · PMID 16982784 · 21 records
• Role of asparaginase variable loop at the carboxyl terminal of the alpha subunit in the determination of substrate preference in plants · PMID 22127737 · 49 records
• Role of aspartate 143 in Escherichia coli tRNA-guanine transglycosylase: alteration of heterocyclic substrate specificity · PMID 16401090 · 6 records
• Role of aspartate 400, arginine 262, and arginine 401 in the catalytic mechanism of human coproporphyrinogen oxidase · PMID 17242372 · 9 records
• Role of Aspartate 86 in the Catalytic Mechanism of Escherichia coli Glutamate Decarboxylase · PMID 41717872 · 20 records
• Role of aspartate-133 and histidine-458 in the mechanism of tryptophan indole-lyase from Proteus vulgaris · PMID 14503866 · 31 records
• Role of connecting loop I in catalysis and allosteric regulation of human glucokinase · PMID 24723372 · 25 records
• Role of coupled dynamics in the catalytic activity of prokaryotic-like prolyl-tRNA synthetases · PMID 22356126 · 6 records
• Role of cysteine 306 in the catalytic mechanism of Ascaris suum phosphoenolpyruvate carboxykinase · PMID 12127066 · 24 records
• Role of cysteine residues in pseudouridine synthases of different families · PMID 10529181 · 9 records
• Role of cytochrome P450 enzymes in fimasartan metabolism in vitro · PMID 29596975 · 9 records
• Role of enzyme-ribofuranosyl contacts in the ground state and transition state for orotidine 5'-phosphate decarboxylase: a role for substrate destabilization? · PMID 11371183 · 5 records
• Role of GldA in dihydroxyacetone and methylglyoxal metabolism of Escherichia coli K12 · PMID 18179582 · 4 records
• Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2 · PMID 16828555 · 7 records
• Role of glutamine-169 in the substrate recognition of human aminopeptidase B · PMID 24412328 · 10 records
• Role of glycine 81 in (S)-mandelate dehydrogenase from Pseudomonas putida in substrate specificity and oxidase activity · PMID 15311930 · 26 records
• Role of His505 in the soluble fumarate reductase from Shewanella frigidimarina · PMID 12093271 · 8 records
• Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1 · PMID 33048542 · 7 records
• Role of hydrogen bonds in the reaction mechanism of chalcone isomerase · PMID 11955065 · 25 records
• Role of key residues at the flavin mononucleotide (FMN):adenylyltransferase catalytic site of the bifunctional riboflavin kinase/flavin adenine dinucleotide (FAD) Synthetase from Corynebacterium… · PMID 23203077 · 42 records
• Role of Loop-Clamping Side Chains in Catalysis by Triosephosphate Isomerase · PMID 26570983 · 35 records
• Role of Lys-32 residues in R67 dihydrofolate reductase probed by asymmetric mutations · PMID 15333636 · 10 records
• Role of lysine-54 in determining cofactor specificity and binding in human dihydrofolate reductase · PMID 2124504 · 6 records
• Role of metal ions in the reaction catalyzed by L-ribulose-5-phosphate 4-epimerase · PMID 10769139 · 26 records
• Role of motif III in catalysis by acetyl-CoA synthetase · PMID 22973162 · 13 records
• Role of N,N-Dimethylglycine and Its Catabolism to Sarcosine in Chromohalobacter salexigens DSM 3043 · PMID 32631860 · 4 records
• Role of non-covalent enzyme-substrate interactions in the reaction catalysed by cellobiose phosphorylase from Cellulomonas uda · PMID 11042119 · 16 records
• Role of proline residues in the folding of serine hydroxymethyltransferase · PMID 12773539 · 9 records
• Role of RecJ-like protein with 5'-3' exonuclease activity in oligo(deoxy)nucleotide degradation · PMID 21087930 · 28 records
• Role of residues 104, 164, 166, 238 and 240 in the substrate profile of PER-1 beta-lactamase hydrolysing third-generation cephalosporins · PMID 9494118 · 44 records
• Role of S'1 loop residues in the substrate specificities of pepsin A and chymosin · PMID 15568804 · 64 records
• Role of S65, Q67, I68, and Y69 residues in homotetrameric R67 dihydrofolate reductase · PMID 11560482 · 12 records
• Role of Ser-238 and Lys-240 in the hydrolysis of third-generation cephalosporins by SHV-type beta-lactamases probed by site-directed mutagenesis and three-dimensional modeling · PMID 8429044 · 28 records
• Role of Ser-257 in the sliding mechanism of NADP(H) in the reaction catalyzed by the Aspergillus fumigatus flavin-dependent ornithine N5-monooxygenase SidA · PMID 24072704 · 8 records
• Role of short-chain hydroxyacyl CoA dehydrogenases in SCHAD deficiency · PMID 18036338 · 11 records
• Role of side-chains in the operation of the main molecular hinge of 3-phosphoglycerate kinase · PMID 18358841 · 22 records
• Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids · PMID 22387545 · 7 records
• Role of subsite +1 residues in pH dependence and catalytic activity of the glycoside hydrolase family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium · PMID 18023045 · 5 records
• Role of the active-site carboxylate in dihydrofolate reductase: kinetic and spectroscopic studies of the aspartate 26-->asparagine mutant of the Lactobacillus casei enzyme · PMID 7893701 · 8 records
• Role of the amino acid invariants in the active site of MurG as evaluated by site-directed mutagenesis · PMID 17692452 · 18 records
• Role of the C-terminal tyrosine of ferredoxin-nicotinamide adenine dinucleotide phosphate reductase in the electron transfer processes with its protein partners ferredoxin and flavodoxin · PMID 15147197 · 11 records
• Role of the C-terminus of Pleurotus eryngii Ery4 laccase in determining enzyme structure, catalytic properties and stability · PMID 22996391 · 55 records
• Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5'-Monophosphate: Transition State Stabilization Dominates Over Ground State Destabilization · PMID 31365243 · 7 records
• Role of the flavin domain residues, His689 and Asn732, in the catalytic mechanism of cellobiose dehydrogenase from phanerochaete chrysosporium · PMID 12680758 · 19 records
• Role of the flexible loop of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus in enzyme catalysis · PMID 11284686 · 18 records
• Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding · PMID 39879323 · 16 records
• Role of the N-terminus in human 4-hydroxyphenylpyruvate dioxygenase activity · PMID 31722428 · 8 records
• Role of the ortholog and paralog amino acid invariants in the active site of the UDP-MurNAc-L-alanine:D-glutamate ligase (MurD) · PMID 10493791 · 44 records
• Role of the Ser-287-Asn replacement in the hydrolysis spectrum extension of AmpC beta-lactamases in Escherichia coli · PMID 19001118 · 26 records
• Role of the Tyr270 residue in 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti · PMID 27568368 · 9 records
• Role of Thr(66) in porcine NADH-cytochrome b5 reductase in catalysis and control of the rate-limiting step in electron transfer · PMID 12459552 · 11 records
• Role of Trp19 and Tyr200 in catalysis by the γ-class carbonic anhydrase from Methanosarcina thermophila · PMID 23111186 · 19 records
• Role of tryptophan 95 in substrate specificity and structural stability of Sulfolobus solfataricus alcohol dehydrogenase · PMID 19588068 · 47 records
• Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide · PMID 20057057 · 12 records
• Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study · PMID 12354107 · 25 records
• Role of yeast glutaredoxins as glutathione S-transferases · PMID 12684511 · 10 records
• Role of Δ1-pyrroline-5-carboxylate dehydrogenase supports mitochondrial metabolism and host-cell invasion of Trypanosoma cruzi · PMID 25623067 · 6 records
• Roles for ALDH10 enzymes in γ-butyrobetaine synthesis, seed development, germination, and salt tolerance in Arabidopsis · PMID 32845293 · 10 records
• Roles for cationic residues at the quinolinic acid binding site of quinolinate phosphoribosyltransferase · PMID 20047306 · 11 records
• Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme · PMID 15182179 · 28 records
• Roles of acetyl-CoA synthetase (ADP-forming) and acetate kinase (PPi-forming) in ATP and PPi supply in Entamoeba histolytica · PMID 26922831 · 16 records
• Roles of acidic residues in SpeG acetyltransferases-insights into importance for kinetic activity and polyamine binding in allosteric and acceptor sites · PMID 42101420 · 20 records
• Roles of active site residues in LodA, a cysteine tryptophylquinone dependent ε-lysine oxidase · PMID 26048732 · 15 records
• Roles of amino acid residues H66 and D326 in the creatine kinase activity and structural stability · PMID 28916380 · 10 records
• Roles of amino acids in the Escherichia coli octaprenyl diphosphate synthase active site probed by structure-guided site-directed mutagenesis · PMID 22471615 · 34 records
• Roles of Arg427 and Arg472 in the binding and allosteric effects of acetyl CoA in pyruvate carboxylase · PMID 22985389 · 40 records
• Roles of conserved basic amino acid residues and activation mechanism of the hyperthermophilic aspartate racemase at high temperature · PMID 16705641 · 25 records
• Roles of His-79 and Tyr-180 of D-xylose/dihydrodiol dehydrogenase in catalytic function · PMID 11097839 · 12 records
• Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase: refined phosphorylation loop structure in the active site · PMID 12902323 · 6 records
• Roles of Ile66 and Ala107 of D-psicose 3-epimerase from Agrobacterium tumefaciens in binding O6 of its substrate, D-fructose · PMID 19728106 · 22 records
• Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity · PMID 14621997 · 12 records
• Roles of low specificity and cofactor interaction sites on thrombin during factor XIII activation. Competition for cofactor sites on thrombin determines its fate · PMID 12794066 · 20 records
• Roles of phosphate recognition in inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) substrate binding and activation · PMID 23884422 · 12 records
• Roles of poly(3-hydroxybutyrate) depolymerase and 3HB-oligomer hydrolase in bacterial PHB metabolism · PMID 15170237 · 31 records
• Roles of the conserved aspartate and arginine in the catalytic mechanism of an archaeal beta-class carbonic anhydrase · PMID 12107142 · 14 records
• Roles of the four DNA polymerases of the crenarchaeon Sulfolobus solfataricus and accessory proteins in DNA replication · PMID 21784862 · 14 records
• Roles of two conserved amino acid residues in the active site of galactose-1-phosphate uridylyltransferase: an essential serine and a nonessential cysteine · PMID 10820011 · 10 records
• Rubisco carboxylation kinetics and inorganic carbon utilization in polar versus cold-temperate seaweeds · PMID 30576461 · 36 records
• S-adenosylhomocysteine hydrolase from the archaeon Pyrococcus furiosus: biochemical characterization and analysis of protein structure by comparative molecular modeling · PMID 15645450 · 3 records
• S-Adenosylmethionine synthetase from Escherichia coli · PMID 6251075 · 14 records
• S-Inosyl-L-Homocysteine Hydrolase, a Novel Enzyme Involved in S-Adenosyl-L-Methionine Recycling · PMID 25917907 · 3 records
• S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity · PMID 23295225 · 20 records
• S-selective hydroxynitrile lyase from a plant Baliospermum montanum: molecular characterization of recombinant enzyme · PMID 21352863 · 19 records
• Saccharomyces cerevisiae Atf1p is an alcohol acetyltransferase and a thioesterase in vitro · PMID 28160314 · 18 records
• Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase · PMID 26774271 · 11 records
• Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis · PMID 9867860 · 23 records
• SacPox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase · PMID 24894602 · 25 records
• Salmonella enterica serovar Typhimurium has three transketolase enzymes contributing to the pentose phosphate pathway · PMID 29848552 · 12 records
• Salmonella enterica serovar typhimurium peptidase B is a leucyl aminopeptidase with specificity for acidic amino acids · PMID 10852868 · 11 records
• Salvage of the 5-deoxyribose byproduct of radical SAM enzymes · PMID 30082730 · 6 records
• Sandalwood fragrance biosynthesis involves sesquiterpene synthases of both the terpene synthase (TPS)-a and TPS-b subfamilies, including santalene synthases · PMID 21454632 · 3 records
• Saturation mutagenesis of putative catalytic residues of benzoylformate decarboxylase provides a challenge to the accepted mechanism · PMID 18398009 · 17 records
• Saturation mutagenesis on Arg244 of the tryptophan C4-prenyltransferase FgaPT2 leads to enhanced catalytic ability and different preferences for tryptophan-containing cyclic dipeptides · PMID 26875876 · 7 records
• Saturation mutagenesis on Tyr205 of the cyclic dipeptide C2-prenyltransferase FtmPT1 results in mutants with strongly increased C3-prenylating activity · PMID 27311563 · 9 records
• Saturation mutagenesis, complement selection, and steady-state kinetic studies illuminate the roles of invariant residues in active site loop I of the hypoxanthine phosphoribosyltransferase from… · PMID 15158715 · 9 records
• Saturation-mutagenesis in two positions distant from active site of a Klebsiella pneumoniae glycerol dehydratase identifies some highly active mutants · PMID 19555728 · 62 records
• Screening and Evaluation of New Hydroxymethylfurfural Oxidases for Furandicarboxylic Acid Production · PMID 32503910 · 16 records
• Screening for hydrolytic enzymes reveals Ayr1p as a novel triacylglycerol lipase in Saccharomyces cerevisiae · PMID 24187129 · 11 records
• Screening of a 4-Ethylguaiacol-Producing Bacillus coagulans JN11 and Biochemical Characterization of Its Phenolic Acid Decarboxylase BcPAD · PMID 42354962 · 3 records
• Screening of Ionic Liquids and Deep Eutectic Solvents for Enhancing the Activity and Stability of Fungal Laccase: Empowering Kinetic Parameters and Long-Term Conservation · PMID 42255576 · 4 records
• Screening, identification, and characterization of a novel saccharide-stimulated β-glycosidase from a soil metagenomic library · PMID 27557720 · 15 records
• Searching sequence space by definably random mutagenesis: improving the catalytic potency of an enzyme · PMID 1967829 · 16 records
• Second generation engineering of transketolase for polar aromatic aldehyde substrates · PMID 25765309 · 9 records
• Secreted fungal sulfhydryl oxidases: sequence analysis and characterisation of a representative flavin-dependent enzyme from Aspergillus oryzae · PMID 20727152 · 5 records
• Secretion of an acid phosphatase provides a possible mechanism to acquire host nutrients by Plasmodium falciparum · PMID 20070315 · 10 records
• Selected mutations in Bacillus subtilis levansucrase semi-conserved regions affecting its biochemical properties · PMID 18596022 · 9 records
• Selecting of a cytochrome P450_cam SeSaM library with 3-chloroindole and endosulfan - Identification of mutants that dehalogenate 3-chloroindole · PMID 28923662 · 7 records
• Selection for growth on 3-nitrotoluene by 2-nitrotoluene-utilizing Acidovorax sp. strain JS42 identifies nitroarene dioxygenases with altered specificities · PMID 25344236 · 54 records
• Selection of a pH- and temperature-stable laccase from Ganoderma australe and its application for bioremediation of textile dyes · PMID 34467865 · 30 records
• Selection of Cyanobacterial (Synechococcus sp. Strain PCC 6301) RubisCO Variants with Improved Functional Properties That Confer Enhanced CO2-Dependent Growth of Rhodobacter… · PMID 31337726 · 30 records
• Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone · PMID 12604236 · 71 records
• Selective cleavage of glycyl bonds by papaya proteinase IV · PMID 2404797 · 9 records
• Selective Engineering of Linkage-Specific α2,6-N-Linked Sialoproteins Using Sydnone-Modified Sialic Acid Bioorthogonal Reporters · PMID 30706985 · 6 records
• Selective inhibition of human 3β-hydroxysteroid dehydrogenase type 1 as a potential treatment for breast cancer · PMID 20736065 · 2 records
• Selective neurotensin-derived internally quenched fluorogenic substrates for neurolysin (EC 3.4.24.16): comparison with thimet oligopeptidase (EC 3.4.24.15) and neprilysin (EC 3.4.24.11) · PMID 11355859 · 36 records
• Selective oxidation of alkyl and aryl glyceryl monoethers catalysed by an engineered and immobilised glycerol dehydrogenase · PMID 34123216 · 19 records
• Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes · PMID 10557352 · 30 records
• Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum · PMID 27697464 · 5 records
• Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase · PMID 27136302 · 14 records
• Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems · PMID 11259642 · 8 records
• Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis · PMID 29194485 · 4 records
• Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides · PMID 36707645 · 8 records
• Semi-rational approach to expand the Acyl-CoA Chain length tolerance of Sphingomonas paucimobilis serine palmitoyltransferase · PMID 32423667 · 10 records
• Semi-rational design and modification of phosphoketolase to improve the yield of tyrosol in Saccharomyces cerevisiae · PMID 39686978 · 8 records
• Semi-rational design and molecular dynamics simulations study of the thermostability enhancement of cellobiose 2-epimerases · PMID 31733243 · 9 records
• Semi-rational engineering of an α-L-fucosidase for regioselective synthesis of fucosyl-N-acetylglucosamine disaccharides · PMID 40034538 · 3 records
• Semi-rational engineering of cellobiose dehydrogenase for improved hydrogen peroxide production · PMID 23617537 · 6 records
• Semi-Rational Engineering of Formate Dehydrogenase Reveals Loop Dynamics as a Key Determinant of Thermostability · PMID 42281337 · 10 records
• Semi-rationally engineered variants of S-adenosylmethionine synthetase from Escherichia coli with reduced product inhibition and improved catalytic activity · PMID 31307578 · 10 records
• Separation and characterization of the 1,3-propanediol and glycerol dehydrogenase activities from Clostridium butyricum E5 wild-type and mutant D · PMID 11412332 · 14 records
• Separation and partial characterization of multiple forms of rat liver alcohol dehydrogenase · PMID 6354095 · 60 records
• Separation and properties of leaf aspartate aminotransferase and alanine aminotransferase isoenzymes operative in the C4 pathway of photosynthesis · PMID 4730471 · 20 records
• Sepiapterin reductase mediates chemical redox cycling in lung epithelial cells · PMID 23640889 · 27 records
• Sequence analysis and biochemical properties of an acidophilic and hyperthermophilic amylopullulanase from Thermofilum pendens · PMID 29551507 · 7 records
• Sequence analysis of glutamate dehydrogenase (GDH) from the hyperthermophilic archaeon Pyrococcus sp. KOD1 and comparison of the enzymatic characteristics of native and recombinant GDHs · PMID 9520268 · 16 records
• Sequence and biochemical analysis of vaccinia virus A32 protein: Implications for in vitro stability and coiled-coil motif mediated regulation of the DNA-dependent ATPase activity · PMID 39761312 · 6 records
• Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with… · PMID 7876235 · 4 records
• Sequence and Structural Motifs Controlling the Broad Substrate Specificity of the Mycobacterial Hormone-Sensitive Lipase LipN · PMID 37065048 · 93 records
• Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase · PMID 12473676 · 6 records
• Sequence of the cDNA of a human dihydrodiol dehydrogenase isoform (AKR1C2) and tissue distribution of its mRNA · PMID 9716498 · 6 records
• Sequence redesign of glycosyltransferases for enhanced heterologous expression and glycosylation efficiency in Escherichia coli · PMID 42310000 · 20 records
• Sequential oxidation of 5-hydroxymethylfurfural to furan-2,5-dicarboxylic acid by an evolved aryl-alcohol oxidase · PMID 31676448 · 2 records
• Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol · PMID 23676275 · 8 records
• Ser475, Glu272, Asp276, Asp327, and Asp360 are involved in catalytic activity of human tripeptidyl-peptidase I · PMID 15733845 · 6 records
• Serendipitous discovery of α-hydroxyalkyl esters as β-lactamase substrates · PMID 21087009 · 14 records
• Serine 363 of a Hydrophobic Region of Archaeal Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase from Archaeoglobus fulgidus and Thermococcus kodakaraensis Affects CO2/O2 Substrate Specificity and… · PMID 26381513 · 15 records
• Serine 51 residue of Citrobacter freundii tyrosine phenol-lyase assists in C-α-proton abstraction and transfer in the reaction with substrate · PMID 29183854 · 12 records
• Serine Acetyltransferase from Pseudomonas aeruginosa: Distinctive Features, Pleiotropic Roles, and Therapeutic Potential · PMID 42278617 · 4 records
• Serine hydroxymethyltransferase from Plasmodium vivax is different in substrate specificity from its homologues · PMID 19549189 · 8 records
• Serine hydroxymethyltransferase from the silkworm Bombyx mori: Identification, distribution, and biochemical characterization · PMID 31298425 · 7 records
• Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity · PMID 15536068 · 16 records
• Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers · PMID 20419721 · 7 records
• SETD3 protein is the actin-specific histidine N-methyltransferase · PMID 30526847 · 6 records
• Severing of a hydrogen bond disrupts amino acid networks in the catalytically active state of the alpha subunit of tryptophan synthase · PMID 25377949 · 9 records
• Shared active sites of fructose-1,6-bisphosphatase. Arginine 243 mediates substrate binding and fructose 2,6-bisphosphate inhibition · PMID 7989306 · 4 records
• Shifting the NAD/NADP preference in class 3 aldehyde dehydrogenase · PMID 11012673 · 22 records
• Shifting the optimal pH of activity for a laccase from the fungus Trametes versicolor by structure-based mutagenesis · PMID 16368720 · 8 records
• Shifting the substrate scope of dimeric pyranose oxidase from monosaccharide to glycoside preference through oligomeric state modification · PMID 39915905 · 3 records
• Significance of Asn-77 and Trp-78 in the catalytic function of undecaprenyl diphosphate synthase of Micrococcus luteus B-P 26 · PMID 11098133 · 21 records
• Significance of H461 at subsite +1 in substrate binding and transglucosylation activity of amylomaltase from Corynebacterium glutamicum · PMID 29885290 · 6 records
• Significance of highly conserved aromatic residues in Micrococcus luteus B-P 26 undecaprenyl diphosphate synthase · PMID 14769870 · 10 records
• Significantly improved catalytic efficiency of caffeic acid O-methyltransferase towards N-acetylserotonin by strengthening its interactions with the unnatural substrate's terminal structure · PMID 30885319 · 5 records
• Simian liver alcohol dehydrogenase: isolation and characterization of isoenzymes from Saimiri sciureus · PMID 7011375 · 18 records
• Similarities and differences in the biochemical and enzymological properties of the four isomaltases from Saccharomyces cerevisiae · PMID 24649402 · 25 records
• Simple and efficient expression of Agaricus meleagris pyranose dehydrogenase in Pichia pastoris · PMID 22080342 · 8 records
• Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues · PMID 23300904 · 8 records
• Simultaneously Enhancing the Stability and Catalytic Activity of Multimeric Lysine Decarboxylase CadA by Engineering Interface Regions for Enzymatic Production of Cadaverine at High Concentration of… · PMID 28843030 · 3 records
• Single Amino Acid Change in 6-Phosphogluconate Dehydrogenase from Synechocystis Conveys Higher Affinity for NADP+ and Altered Mode of Inhibition by NADPH · PMID 30107441 · 40 records
• Single amino acid mutation altered substrate specificity for L-glucose and inositol in scyllo-inositol dehydrogenase isolated from Paracoccus laeviglucosivorans · PMID 31842701 · 8 records
• Single amino acid mutations, but not common polymorphisms, decrease the activity of CYP1B1 against (-)benzo[a]pyrene-7R-trans-7,8-dihydrodiol · PMID 12807732 · 22 records
• Single amino acid substitution in Bacillus sphaericus phenylalanine dehydrogenase dramatically increases its discrimination between phenylalanine and tyrosine substrates · PMID 12234181 · 86 records
• Single arginine mutation in two yeast isocitrate dehydrogenases: biochemical characterization and functional implication · PMID 25502799 · 26 records
• Single-atom substitution redirects KatG reactivity from cofactor biogenesis to stereoselective sulfoxidation · PMID 42288482 · 6 records
• Single-Molecule Imaging of Wood Xylans on Surfaces and Their Interaction with GH11 Xylanase · PMID 40014065 · 4 records
• Single-residue engineering of Klenow fragment enables broad acceptance of chemically modified nucleotides · PMID 42454372 · 8 records
• SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2 · PMID 32457458 · 10 records
• Site directed mutagenesis of amino acid residues at the active site of mouse aldehyde oxidase AOX1 · PMID 19401776 · 28 records
• Site Saturation Mutagenesis Applications on Candida methylica Formate Dehydrogenase · PMID 27847673 · 25 records
• Site-directed fluorescence labeling reveals differences on the R-conformer of glucosamine 6-phosphate deaminase of Escherichia coli induced by active or allosteric site ligands at steady state · PMID 16285712 · 6 records
• Site-Directed Immobilization of DuraPETase onto PET-Binding PDA@SiO₂ for High-Efficiency PET Degradation · PMID 42197229 · 2 records
• Site-directed mutagenesis and halophilicity of dihydrolipoamide dehydrogenase from the halophilic archaeon, Haloferax volcanii · PMID 9346289 · 20 records
• Site-directed mutagenesis combined with chemical modification as a strategy for altering the specificity of the S1 and S1' pockets of subtilisin Bacillus lentus · PMID 9558332 · 17 records
• Site-directed mutagenesis experiments on the putative deprotonation site of squalene-hopene cyclase from Alicyclobacillus acidocaldarius · PMID 15056909 · 39 records
• Site-directed mutagenesis of a conserved Asn450 residue of Bacillus licheniformis γ-glutamyltranspeptidase · PMID 27246377 · 5 records
• Site-directed mutagenesis of a hexapeptide segment involved in substrate recognition of phenylalanine dehydrogenase from Thermoactinomyces intermedius · PMID 8407879 · 30 records
• Site-directed mutagenesis of a loop at the active site of E1 (alpha2beta2) of the pyruvate dehydrogenase complex. A possible common sequence motif · PMID 12603319 · 20 records
• Site-directed mutagenesis of active site residues of phosphite dehydrogenase · PMID 15779903 · 16 records
• Site-directed mutagenesis of arginine 179 of thymidylate synthase. A nonessential substrate-binding residue · PMID 2182628 · 10 records
• Site-directed mutagenesis of ATP binding residues of biotin carboxylase. Insight into the mechanism of catalysis · PMID 11346647 · 21 records
• Site-directed mutagenesis of beta-lactamase I. Single and double mutants of Glu-166 and Lys-73 · PMID 1980064 · 28 records
• Site-directed mutagenesis of beta-lactamase I: role of Glu-166 · PMID 7910734 · 20 records
• Site-directed mutagenesis of catalytic residues in N(5)-carboxyaminoimidazole ribonucleotide synthetase · PMID 23899325 · 20 records
• Site-directed mutagenesis of catalytic residues of influenza virus neuraminidase as an aid to drug design · PMID 9874196 · 8 records
• Site-directed mutagenesis of conserved aromatic residues in rat squalene epoxidase · PMID 17112472 · 26 records
• Site-directed mutagenesis of disulfide bridges in Aspergillus niger NRRL 3135 phytase (PhyA), their expression in Pichia pastoris and catalytic characterization · PMID 20376636 · 5 records
• Site-directed mutagenesis of Escherichia coli acetylglutamate kinase and aspartokinase III probes the catalytic and substrate-binding mechanisms of these amino acid kinase family enzymes and allows… · PMID 14623187 · 22 records
• Site-directed mutagenesis of essential residues involved in the mechanism of bacterial glycosylasparaginase · PMID 9545303 · 31 records
• Site-directed mutagenesis of human dihydrolipoamide dehydrogenase: role of lysine-54 and glutamate-192 in stabilizing the thiolate-FAD intermediate · PMID 10336857 · 13 records
• Site-directed mutagenesis of human leukotriene C4 synthase · PMID 9153254 · 36 records
• Site-directed mutagenesis of human membrane-associated ganglioside sialidase: identification of amino-acid residues contributing to substrate specificity · PMID 11298736 · 13 records
• Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors · PMID 26242695 · 7 records
• Site-directed mutagenesis of possible catalytic residues of cellobiose 2-epimerase from Ruminococcus albus · PMID 19330485 · 17 records
• Site-directed mutagenesis of proline 204 in the 'hinge' region of yeast phosphoglycerate kinase · PMID 10092885 · 4 records
• Site-directed mutagenesis of putative substrate-binding residues reveals a mechanism controlling the different stereospecificities of two tropinone reductases · PMID 10347221 · 41 records
• Site-directed mutagenesis of selected residues at the active site of aryl-alcohol oxidase, an H2O2-producing ligninolytic enzyme · PMID 16999821 · 26 records
• Site-directed mutagenesis of the active site glutamate in human matrilysin: investigation of its role in catalysis · PMID 9398337 · 5 records
• Site-directed mutagenesis of the active site region in the quinate/shikimate 5-dehydrogenase YdiB of Escherichia coli · PMID 15596430 · 30 records
• Site-directed mutagenesis of the amino acid residues in beta-strand III [Val30-Val36] of D-amino acid aminotransferase of Bacillus sp. YM-1 · PMID 8977094 · 14 records
• Site-directed mutagenesis of the catalytic tryptophan environment in Pleurotus eryngii versatile peroxidase · PMID 18201105 · 43 records
• Site-directed mutagenesis of the conserved residues in component I of Bacillus subtilis heptaprenyl diphosphate synthase · PMID 10545188 · 28 records
• Site-directed mutagenesis of the putative active site of endoglucanase K from Bacillus sp. KSM-330 · PMID 8075149 · 6 records
• Site-directed mutagenesis of the substrate-binding cleft of human estrogen sulfotransferase · PMID 11006110 · 18 records
• Site-directed mutagenesis of yeast phosphoglycerate kinase. Arginines 65, 121 and 168 · PMID 8462685 · 14 records
• Site-directed mutagenesis studies on the determinants of sugar specificity and cooperative behavior of human beta-cell glucokinase · PMID 7961659 · 39 records
• Site-directed mutagenesis studies on the L-arginine-binding sites of feedback inhibition in N-acetyl-L-glutamate kinase (NAGK) from Corynebacterium glutamicum · PMID 22101454 · 34 records
• Site-directed mutagenesis study of the microenvironment characteristics of Lys213 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase · PMID 16469427 · 9 records
• Site-directed mutation of conserved cysteine residues does not inactivate the Streptococcus pyogenes hyaluronan synthase · PMID 11805074 · 18 records
• Site-directed mutational analysis of active site residues in the acetate kinase from Methanosarcina thermophila · PMID 11562377 · 27 records
• Site-saturation mutagenesis of Tyr-105 reveals its importance in substrate stabilization and discrimination in TEM-1 beta-lactamase · PMID 15326193 · 12 records
• Site-specific α-glycosylation of hydroxyflavones and hydroxyflavanones by amylosucrase from Deinococcus geothermalis · PMID 31307576 · 4 records
• Slow PP_i release enhances fidelity of the SARS-CoV-2 RNA dependent RNA polymerase · PMID 41999896 · 14 records
• Snake venom fibrin(ogen)olytic enzymes · PMID 15882884 · 11 records
• Sodium chloride-induced modulation of the activity and thermal stability of short-chain oxidoreductase from the archaeon Thermococcus sibiricus · PMID 24061874 · 12 records
• Solubilization and Iterative Saturation Mutagenesis of α1,3-fucosyltransferase from Helicobacter pylori to enhance its catalytic efficiency · PMID 26804479 · 12 records
• Solubilization, molecular forms, purification and substrate specificity of two acetylcholinesterases in the medicinal leech (Hirudo medicinalis) · PMID 7702560 · 12 records
• Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer · PMID 31201273 · 8 records
• Some kinetic properties of pyruvate kinase from Trypanosoma brucei · PMID 1371328 · 22 records
• Sorbitol dehydrogenase from bovine lens: purification and properties · PMID 9143345 · 11 records
• Soybean nodule xanthine dehydrogenase: a kinetic study · PMID 6573870 · 23 records
• Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose-1,6-bisphosphate aldolase · PMID 12611890 · 7 records
• Spatial requirement for PAMO for transformation of non-native linear substrates · PMID 29318252 · 2 records
• Spatially restricted substrate-binding site of cortisol-synthesizing CYP11B1 limits multiple hydroxylations and hinders aldosterone synthesis · PMID 34485929 · 8 records
• Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse · PMID 22207054 · 28 records
• Species variation in kinetic properties of ribulose 1,5-bisphosphate carboxylase/oxygenase · PMID 6582802 · 22 records
• Specific Activation of the Plant P-type Plasma Membrane H+-ATPase by Lysophospholipids Depends on the Autoinhibitory N- and C-terminal Domains · PMID 25971968 · 22 records
• Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES · PMID 26555264 · 8 records
• Specific interaction of cytosolic and mitochondrial glyoxalase II with acidic phospholipids in form of liposomes results in the inhibition of the cytosolic enzyme only · PMID 10944391 · 10 records
• Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase · PMID 24895213 · 6 records
• Specificity and enzyme kinetics of the quorum-quenching N-Acyl homoserine lactone lactonase (AHL-lactonase) · PMID 14734559 · 10 records
• Specificity and kinetics of triose phosphate isomerase from chicken muscle · PMID 4643318 · 3 records
• Specificity and mechanism of mandelamide hydrolase catalysis · PMID 28129982 · 12 records
• Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in… · PMID 15472229 · 42 records
• Specificity determinants for lysine incorporation in Staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex · PMID 24064214 · 2 records
• Specificity inversion of Ochrobactrum anthropi D-aminopeptidase to a D,D-carboxypeptidase with new penicillin binding activity by directed mutagenesis · PMID 16131658 · 15 records
• Specificity of a prodrug-activating enzyme hVACVase: the leaving group effect · PMID 21028903 · 6 records
• Specificity of activated human protein C · PMID 3863616 · 12 records
• Specificity of Aeromonas aminopeptidase toward amino acid amides and dipeptides · PMID 5010066 · 20 records
• Specificity of aminoacylase III-mediated deacetylation of mercapturic acids · PMID 17012540 · 20 records
• Specificity of human alcohol dehydrogenase 1C*2 (gamma2gamma2) for steroids and simulation of the uncompetitive inhibition of ethanol metabolism · PMID 12604203 · 7 records
• Specificity of S'1 and S'2 subsites of human tissue kallikrein using the reactive-centre loop of kallistatin: the importance of P'1 and P'2 positions in design of inhibitors · PMID 12578561 · 8 records
• Specificity of Streptomyces griseus aminopeptidase and modulation of activity by divalent metal ion binding and substitution · PMID 8444149 · 12 records
• Specificity of the trypanothione-dependent Leishmania major glyoxalase I: structure and biochemical comparison with the human enzyme · PMID 16430697 · 10 records
• Specificity of the wound-induced leucine aminopeptidase (LAP-A) of tomato activity on dipeptide and tripeptide substrates · PMID 10672029 · 10 records
• Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function · PMID 4026306 · 13 records
• Specificity studies on Kallikrein-related peptidase 7 (KLK7) and effects of osmolytes and glycosaminoglycans on its peptidase activity · PMID 25448018 · 43 records
• Spectral and catalytic properties of aryl-alcohol oxidase, a fungal flavoenzyme acting on polyunsaturated alcohols · PMID 15813702 · 15 records
• Spectral and kinetic properties of the Fet3 protein from Saccharomyces cerevisiae, a multinuclear copper ferroxidase enzyme · PMID 9722559 · 4 records
• Spectrophotometric assay for detection of aromatic hydroxylation catalyzed by fungal haloperoxidase-peroxygenase · PMID 17410351 · 1 record
• Sphingadienine-1-phosphate levels are regulated by a novel glycoside hydrolase family 1 glucocerebrosidase widely distributed in seed plants · PMID 34563538 · 9 records
• SPIN-guided engineering of a novel (R)-amine transaminase from Fusarium albosuccineum for enantioselective synthesis of chiral piperidyl amines · PMID 41551743 · 2 records
• Stabilization of a metabolic enzyme by library selection in Thermus thermophilus · PMID 21455924 · 16 records
• Stabilization of Hydroxynitrile Lyases from Two Variants of Passion Fruit, Passiflora edulis Sims and Passiflora edulis Forma flavicarpa, by C-Terminal Truncation · PMID 31562666 · 9 records
• Staphylococcal SplA and SplB Serine Protease Allelic Variants Exhibit Different Substrate Specificities · PMID 41424281 · 12 records
• Staphylococcus aureus CstB Is a Novel Multidomain Persulfide Dioxygenase-Sulfurtransferase Involved in Hydrogen Sulfide Detoxification · PMID 26177047 · 12 records
• Staphylopine, pseudopaline, and yersinopine dehydrogenases: A structural and kinetic analysis of a new functional class of opine dehydrogenase · PMID 29618515 · 17 records
• Stapled histone H3 tails are super-substrates for lysine methyltransferase SETD7 · PMID 41383456 · 8 records
• Steady state kinetic analysis of O-linked GalNAc glycan release catalyzed by endo-α-N-acetylgalactosaminidase · PMID 31176190 · 6 records
• Steady-state and pre-steady-state kinetic analysis of halopropane conversion by a rhodococcus haloalkane dehalogenase · PMID 12834356 · 9 records
• Steady-state and pre-steady-state kinetic analysis of Mycobacterium tuberculosis pantothenate synthetase · PMID 11669627 · 13 records
• Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis · PMID 18237196 · 14 records
• Steady-state and transient kinetic analyses of taurine/alpha-ketoglutarate dioxygenase: effects of oxygen concentration, alternative sulfonates, and active-site variants on the FeIV-oxo intermediate · PMID 15751960 · 26 records
• Steady-state and transient kinetics of Escherichia coli nitric-oxide dioxygenase (flavohemoglobin). The B10 tyrosine hydroxyl is essential for dioxygen binding and catalysis · PMID 10777548 · 13 records
• Steady-state kinetic characterization of RB69 DNA polymerase mutants that affect dNTP incorporation · PMID 10387055 · 39 records
• Steady-state kinetic mechanism of Escherichia coli UDP-N-acetylenolpyruvylglucosamine reductase · PMID 7727397 · 31 records
• Steady-state kinetics and mechanism of LpxD, the N-acyltransferase of lipid A biosynthesis · PMID 18422345 · 24 records
• Steady-state kinetics and mutational studies of recombinant human thiamin pyrophosphokinase · PMID 12953792 · 17 records
• Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis. The role of the allosteric activator GTP incoupling between glutamine hydrolysis and CTP synthesis · PMID 12354108 · 12 records
• Steady-state kinetics of the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi · PMID 15210120 · 8 records
• Stereoselective catalysis controlled by a native leucine or variant isoleucine wing-gatekeeper in 2-haloacid dehalogenase · PMID 30499103 · 8 records
• Stereoselective Formation of Multiple Reaction Products by the Phosphotriesterase from Sphingobium sp. TCM1 · PMID 32167750 · 33 records
• Stereoselective hydrolysis of organophosphate nerve agents by the bacterial phosphotriesterase · PMID 20701311 · 447 records
• Steric Control of the Rate-Limiting Step of UDP-Galactopyranose Mutase · PMID 29757624 · 4 records
• Steroid-binding site residues dictate optimal substrate positioning in rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD or AKR1C9) · PMID 12604226 · 35 records
• Sterol 3β-glucosyltransferase biocatalysts with a range of selectivities, including selectivity for testosterone · PMID 24056940 · 7 records
• Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesis · PMID 14717613 · 9 records
• Sterylglucoside catabolism in Cryptococcus neoformans with endoglycoceramidase-related protein 2 (EGCrP2), the first steryl-β-glucosidase identified in fungi · PMID 25361768 · 4 records
• Stimulation of KatG catalase activity by peroxidatic electron donors · PMID 22705398 · 10 records
• STM2360 encodes a d-ornithine/d-lysine decarboxylase in Salmonella enterica serovar typhimurium · PMID 29024617 · 2 records
• Streptococcus pneumoniae GAPN is a key metabolic player necessary for host infection · PMID 39660954 · 6 records
• Streptomyces coelicolor RedP and FabH enzymes, initiating undecylprodiginine and fatty acid biosynthesis, exhibit distinct acyl-CoA and malonyl-acyl carrier protein substrate specificities · PMID 22136753 · 10 records
• Structural analysis of CYP2R1 in complex with vitamin D3 · PMID 18511070 · 3 records
• Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases · PMID 25422158 · 5 records
• Structural analysis of Saccharomyces cerevisiae alpha-galactosidase and its complexes with natural substrates reveals new insights into substrate specificity of GH27 glycosidases · PMID 20592022 · 9 records
• Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase · PMID 18627175 · 9 records
• Structural analysis of the FMN binding domain of NADPH-cytochrome P-450 oxidoreductase by site-directed mutagenesis · PMID 2708380 · 11 records
• Structural analysis of thermostabilizing mutations of cocaine esterase · PMID 20436035 · 5 records
• Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis · PMID 33299080 · 8 records
• Structural and biochemical analyses of Microcystis aeruginosa O-acetylserine sulfhydrylases reveal a negative feedback regulation of cysteine biosynthesis · PMID 24275508 · 18 records
• Structural and biochemical analysis of a type II free methionine-R-sulfoxide reductase from Thermoplasma acidophilum · PMID 25043974 · 3 records
• Structural and biochemical approaches uncover multiple evolutionary trajectories of plant quinate dehydrogenases · PMID 29890023 · 22 records
• Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum · PMID 34200865 · 5 records
• Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia · PMID 38701795 · 6 records
• Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties · PMID 30050039 · 5 records
• Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes · PMID 27785912 · 34 records
• Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity · PMID 26115006 · 12 records
• Structural and Biochemical Characterization of Aldehyde Dehydrogenase 12, the Last Enzyme of Proline Catabolism in Plants · PMID 30580036 · 24 records
• Structural and Biochemical Characterization of Apicomplexan Inorganic Pyrophosphatases · PMID 28701714 · 15 records
• Structural and Biochemical Characterization of Cinnamoyl-CoA Reductases · PMID 27956488 · 14 records
• Structural and biochemical characterization of free methionine-R-sulfoxide reductase from Neisseria meningitidis · PMID 20489204 · 16 records
• Structural and biochemical characterization of fructose-1,6/sedoheptulose-1,7-bisphosphatase from the cyanobacterium Synechocystis strain 6803 · PMID 24286336 · 16 records
• Structural and Biochemical Characterization of Porcine Epidemic Diarrhea Virus Papain-Like Protease 2 · PMID 34643430 · 7 records
• Structural and biochemical characterization of Siw14: A protein-tyrosine phosphatase fold that metabolizes inositol pyrophosphates · PMID 29540476 · 13 records
• Structural and biochemical characterization of the broad substrate specificity of Bacteroides thetaiotaomicron commensal sialidase · PMID 23665536 · 5 records
• Structural and biochemical characterization of the nucleoside hydrolase from C. elegans reveals the role of two active site cysteine residues in catalysis · PMID 28218438 · 15 records
• Structural and biochemical characterization of the type II fructose-1,6-bisphosphatase GlpX from Escherichia coli · PMID 19073594 · 7 records
• Structural and biochemical characterization of the yeast HD domain containing protein YGK1 reveals a metal-dependent nucleoside 5'-monophosphatase · PMID 29752939 · 5 records
• Structural and biochemical elucidation of mechanism for decarboxylative condensation of beta-keto acid by curcumin synthase · PMID 21148316 · 6 records
• Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis · PMID 19812041 · 14 records
• Structural and biochemical insights into an engineered high-redox potential laccase overproduced in Aspergillus · PMID 31505206 · 12 records
• Structural and biochemical insights into the catalytic mechanisms of two insect chitin deacetylases of the carbohydrate esterase 4 family · PMID 30755482 · 6 records
• Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases · PMID 30276262 · 8 records
• Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum · PMID 42630012 · 4 records
• Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality · PMID 27578891 · 8 records
• Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from Leishmania major · PMID 31743022 · 16 records
• Structural and biochemical properties of cloned and expressed human and rat steroid 5 alpha-reductases · PMID 2339109 · 6 records
• Structural and biochemical studies enlighten the unspecific peroxygenase from Hypoxylon sp. EC38 as an efficient oxidative biocatalyst · PMID 34540338 · 6 records
• Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity · PMID 20836570 · 15 records
• Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria · PMID 21998747 · 10 records
• Structural and biochemical studies of the glucuronoyl esterase OtCE15A illuminate its interaction with lignocellulosic components · PMID 31740581 · 8 records
• Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization · PMID 21592965 · 7 records
• Structural and catalytic diversity in the two family 11 aldo-keto reductases · PMID 15019785 · 9 records
• Structural and Catalytic Roles of the Disulfide Bonds Cys19-Cys154 and Cys134-Cys199 in Trypsin-like Proteases: Evolutionary Insights for Disulfide Bond Acquisition · PMID 41599399 · 4 records
• Structural and enzymatic analyses of Anabaena heterocyst-specific alkaline invertase InvB · PMID 29578606 · 5 records
• Structural and enzymatic characterization of BacD, an L-amino acid dipeptide ligase from Bacillus subtilis · PMID 22407814 · 14 records
• Structural and enzymatic characterization of DR1281: A calcineurin-like phosphoesterase from Deinococcus radiodurans · PMID 17847097 · 8 records
• Structural and enzymatic characterization of Os3BGlu6, a rice beta-glucosidase hydrolyzing hydrophobic glycosides and (1->3)- and (1->2)-linked disaccharides · PMID 19587102 · 10 records
• Structural and enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus · PMID 23071703 · 48 records
• Structural and enzymatic properties of a gastric NADP(H)- dependent and retinal-active alcohol dehydrogenase · PMID 10473548 · 29 records
• Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family · PMID 21914792 · 10 records
• Structural and functional analyses of beta-glucosidase 3B from Thermotoga neapolitana: a thermostable three-domain representative of glycoside hydrolase 3 · PMID 20138890 · 14 records
• Structural and functional analyses of human tryptophan 2,3-dioxygenase · PMID 25066423 · 7 records
• Structural and functional analyses of the human-type corrinoid adenosyltransferase (PduO) from Lactobacillus reuteri · PMID 17988155 · 19 records
• Structural and functional analysis of a conjugated bile salt hydrolase from Bifidobacterium longum reveals an evolutionary relationship with penicillin V acylase · PMID 16905539 · 10 records
• Structural and functional analysis of a glycoside hydrolase family 97 enzyme from Bacteroides thetaiotaomicron · PMID 18981178 · 13 records
• Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance · PMID 12417303 · 10 records
• Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway · PMID 19483088 · 6 records
• Structural and functional analysis of Erwinia amylovora SrlD. The first crystal structure of a sorbitol-6-phosphate 2-dehydrogenase · PMID 29605571 · 4 records
• Structural and functional analysis of hydroxynitrile lyase from Baliospermum montanum with crystal structure, molecular dynamics and enzyme kinetics · PMID 25220808 · 5 records
• Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase · PMID 15933070 · 24 records
• Structural and functional analysis of substrate recognition by the 250s loop in amylomaltase from Thermus brockianus · PMID 21117235 · 4 records
• Structural and functional analysis of tetracenomycin F2 cyclase from Streptomyces glaucescens. A type II polyketide cyclase · PMID 15231835 · 8 records
• Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design · PMID 17610893 · 8 records
• Structural and functional characterization of a noncanonical nucleoside triphosphate pyrophosphatase from Thermotoga maritima · PMID 23385455 · 6 records
• Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii · PMID 15128743 · 6 records
• Structural and functional characterization of BaiA, an enzyme involved in secondary bile acid synthesis in human gut microbe · PMID 23836456 · 30 records
• Structural and functional characterization of elastases from horse neutrophils · PMID 7516152 · 4 records
• Structural and functional characterization of Escherichia coli UMP kinase in complex with its allosteric regulator GTP · PMID 18945668 · 22 records
• Structural and functional characterization of M. tuberculosis sedoheptulose- 7-phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway · PMID 33257730 · 14 records
• Structural and functional characterization of plant aminoaldehyde dehydrogenase from Pisum sativum with a broad specificity for natural and synthetic aminoaldehydes · PMID 20026072 · 10 records
• Structural and Functional Characterization of Plasmodium falciparum Nicotinic Acid Mononucleotide Adenylyltransferase · PMID 27984041 · 12 records
• Structural and functional characterization of rabbit and human L-gulonate 3-dehydrogenase · PMID 15809331 · 41 records
• Structural and functional characterization of the α-tubulin acetyltransferase MEC-17 · PMID 24846647 · 20 records
• Structural and functional characterization of two-domain laccase from Streptomyces viridochromogenes · PMID 25778839 · 4 records
• Structural and functional comparison of two human liver dihydrodiol dehydrogenases associated with 3 alpha-hydroxysteroid dehydrogenase activity · PMID 1554355 · 40 records
• Structural and functional consequences of single amino acid substitutions in the pyrimidine base binding pocket of Escherichia coli CMP kinase · PMID 17542990 · 20 records
• Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA) · PMID 29728457 · 11 records
• Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase · PMID 16210326 · 5 records
• Structural and functional evolution of isopropylmalate dehydrogenases in the leucine and glucosinolate pathways of Arabidopsis thaliana · PMID 21697089 · 12 records
• Structural and functional highlights of methionine aminopeptidase 2 from Leishmania donovani · PMID 29680505 · 6 records
• Structural and functional impairment of an Old Yellow Enzyme homologue upon affinity tag incorporation · PMID 15249051 · 5 records
• Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I · PMID 12820884 · 9 records
• Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana · PMID 22493446 · 3 records
• Structural and functional insights into (S)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization · PMID 23284870 · 20 records
• Structural and Functional Insights into a Honey Bee Omega-Class Glutathione S-Transferase Mediating Chemical Sequestration and Antioxidative Stress · PMID 42205059 · 10 records
• Structural and functional insights into RHA-P, a bacterial GH106 α-L-rhamnosidase from Novosphingobium sp. PP1Y · PMID 29678627 · 7 records
• Structural and functional investigations of Pcal_0606, a bifunctional phosphoglucose/phosphomannose isomerase from Pyrobaculum calidifontis · PMID 39208883 · 3 records
• Structural and functional modularity of proteins in the de novo purine biosynthetic pathway · PMID 19384989 · 12 records
• Structural and functional modulation of human kynurenine aminotransferase I enhances selenium-driven redox metabolism for cancer therapy · PMID 41412036 · 44 records
• Structural and functional properties of aldose xylose reductase from the D-xylose-metabolizing yeast Candida tenuis · PMID 11306077 · 4 records
• Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1) · PMID 31784620 · 18 records
• Structural and functional significance of the highly-conserved residues in Mycobacterium tuberculosis acetohydroxyacid synthase · PMID 24731825 · 6 records
• Structural and functional similarities in the ADP-forming amide bond ligase superfamily: implications for a substrate-induced conformational change in folylpolyglutamate synthetase · PMID 10970743 · 18 records
• Structural and functional studies of the glycoside hydrolase family 3 β-glucosidase Cel3A from the moderately thermophilic fungus Rasamsonia emersonii · PMID 27377383 · 5 records
• Structural and functional studies of WlbA: A dehydrogenase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid · PMID 20690587 · 4 records
• Structural and functional studies suggest a catalytic mechanism for the phosphotransacetylase from Methanosarcina thermophila · PMID 16428418 · 16 records
• Structural and kinetic analyses of arginine residues in the active site of the acetate kinase from Methanosarcina thermophila · PMID 15647264 · 35 records
• Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition · PMID 16781734 · 8 records
• Structural and kinetic analysis of catalysis by a thiamin diphosphate-dependent enzyme, benzoylformate decarboxylase · PMID 12590569 · 4 records
• Structural and kinetic analysis of Schwanniomyces occidentalis invertase reveals a new oligomerization pattern and the role of its supplementary domain in substrate binding · PMID 20181943 · 27 records
• Structural and kinetic basis for substrate selectivity in Populus tremuloides sinapyl alcohol dehydrogenase · PMID 15829607 · 6 records
• Structural and Kinetic Basis for the Rational Design of Next-Generation β-Lactamase Inhibitors · PMID 41838618 · 8 records
• Structural and kinetic basis of steroid 17α,20-lyase activity in teleost fish cytochrome P450 17A1 and its absence in cytochrome P450 17A2 · PMID 25533464 · 6 records
• Structural and kinetic characterization of 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate aldolase, a protocatechuate degradation enzyme evolutionarily convergent with the HpaI… · PMID 20843800 · 11 records
• Structural and Kinetic Characterization of the SpeG Spermidine/Spermine N-acetyltransferase from Methicillin-Resistant Staphylococcus aureus USA300 · PMID 37508494 · 6 records
• Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major · PMID 25978379 · 7 records
• Structural and kinetic characterization of Trypanosoma congolense pyruvate kinase · PMID 32084384 · 6 records
• Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase · PMID 18601654 · 12 records
• Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates · PMID 22123821 · 14 records
• Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae · PMID 22229411 · 17 records
• Structural and kinetic properties of chymotrypsin from Atlantic cod (Gadus morhua). Comparison with bovine chymotrypsin · PMID 1764912 · 24 records
• Structural and kinetic properties of nonglycosylated recombinant Penicillium amagasakiense glucose oxidase expressed in Escherichia coli · PMID 9546178 · 7 records
• Structural and kinetic properties of serine hydroxymethyltransferase from the halophytic cyanobacterium Aphanothece halophytica provide a rationale for salt tolerance · PMID 32417544 · 70 records
• Structural and kinetic studies of a series of mutants of galactose oxidase identified by directed evolution · PMID 15047910 · 36 records
• Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii · PMID 27100912 · 2 records
• Structural and kinetic studies of induced fit in xylulose kinase from Escherichia coli · PMID 17123542 · 13 records
• Structural and kinetic studies of sugar binding to galactose mutarotase from Lactococcus lactis · PMID 12218067 · 6 records
• Structural and Mechanistic Analysis of the Choline Sulfatase from Sinorhizobium melliloti: A Class I Sulfatase Specific for an Alkyl Sulfate Ester · PMID 29458126 · 34 records
• Structural and mechanistic basis of sulfolytic C-S bond cleavage by an Fe(ii)/α-ketoglutarate-dependent sulfoquinovose dioxygenase · PMID 41777709 · 2 records
• Structural and mechanistic characterization of L-histidinol phosphate phosphatase from the polymerase and histidinol phosphatase family of proteins · PMID 23327428 · 24 records
• Structural and Mechanistic Insights Into Dimethylsulfoxide Formation Through Dimethylsulfide Oxidation · PMID 34630359 · 13 records
• Structural and mechanistic insights into the substrate specificity and hydrolysis of GH31 α-N-acetylgalactosaminidase · PMID 34826537 · 10 records
• Structural and mechanistic investigations on Salmonella typhimurium acetate kinase (AckA): identification of a putative ligand binding pocket at the dimeric interface · PMID 23031654 · 11 records
• Structural and mechanistic roles of three consecutive Pro residues of porcine NADH-cytochrome b(5) reductase for the binding of beta-NADH · PMID 19716516 · 26 records
• Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme · PMID 15684426 · 18 records
• Structural and mechanistic studies of HpxO, a novel flavin adenine dinucleotide-dependent urate oxidase from Klebsiella pneumoniae · PMID 23259842 · 5 records
• Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases · PMID 19728741 · 14 records
• Structural and mutational analyses reveal the functional role of active-site Lys-154 and Asp-173 of Salmonella typhimurium AphA protein · PMID 17570338 · 5 records
• Structural and mutational analysis of amino acid residues involved in ATP specificity of Escherichia coli acetate kinase · PMID 24856051 · 8 records
• Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus · PMID 16714288 · 15 records
• Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferase · PMID 15099582 · 14 records
• Structural and redox properties of the small laccase Ssl1 from Streptomyces sviceus · PMID 24548692 · 6 records
• Structural aspects of the distinct biochemical properties of glutaredoxin 1 and glutaredoxin 2 from Saccharomyces cerevisiae · PMID 18992757 · 9 records
• Structural asymmetry and disulfide bridges among subunits modulate the activity of human malonyl-CoA decarboxylase · PMID 23482565 · 14 records
• Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic acid, and role of the invariant glutamine · PMID 21483814 · 6 records
• Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase · PMID 17158155 · 16 records
• Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen… · PMID 15274625 · 21 records
• Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis · PMID 17507985 · 7 records
• Structural basis for cofactor-independent dioxygenation of N-heteroaromatic compounds at the alpha/beta-hydrolase fold · PMID 20080731 · 8 records
• Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum · PMID 10206992 · 7 records
• Structural basis for dual nucleotide selectivity of aminoglycoside 2''-phosphotransferase IVa provides insight on determinants of nucleotide specificity of aminoglycoside kinases · PMID 22371504 · 6 records
• Structural basis for interdomain communication in SHIP2 providing high phosphatase activity · PMID 28792888 · 20 records
• Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase · PMID 34562453 · 13 records
• Structural basis for L-lysine feedback inhibition of homocitrate synthase · PMID 20089861 · 8 records
• Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain · PMID 15894617 · 23 records
• Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD · PMID 26183229 · 10 records
• Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A · PMID 26792860 · 11 records
• Structural basis for nucleotide recognition by the ectoenzyme CD203c · PMID 29717535 · 15 records
• Structural basis for oxidative decarboxylation of lignin-derived aromatics by the fungal flavoprotein monooxygenase PcMNX1 · PMID 42567519 · 21 records
• Structural Basis for Specificity and Flexibility in a Plant 4-Coumarate:CoA Ligase · PMID 26412334 · 21 records
• Structural basis for substrate binding, catalysis, and inhibition of cancer target mitochondrial creatine kinase by a covalent inhibitor · PMID 39904336 · 26 records
• Structural basis for substrate recognition and inhibition of prephenate aminotransferase from Arabidopsis · PMID 29405514 · 12 records
• Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development · PMID 42030356 · 2 records
• Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains · PMID 20356844 · 6 records
• Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1 · PMID 22615379 · 8 records
• Structural basis for substrate specificity in group I nucleoside hydrolases · PMID 18361502 · 21 records
• Structural basis for substrate specificity in phosphate binding (beta/alpha)8-barrels: D-allulose 6-phosphate 3-epimerase from Escherichia coli K-12 · PMID 18700786 · 19 records
• Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase · PMID 12937174 · 7 records
• Structural basis for substrate specificity of methylsuccinyl-CoA dehydrogenase, an unusual member of the acyl-CoA dehydrogenase family · PMID 29275330 · 5 records
• Structural basis for substrate-specific acetylation of Nα-acetyltransferase Ard1 from Sulfolobus solfataricus · PMID 25728374 · 4 records
• Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant · PMID 16828705 · 22 records
• Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase · PMID 26276389 · 27 records
• Structural basis for the bifunctionality of fructose-1,6-bisphosphate aldolase/phosphatase · PMID 21983966 · 7 records
• Structural basis for the broad specificity of a new family of amino-acid racemases · PMID 24419381 · 10 records
• Structural basis for the catalytic mechanism of aspartate ammonia lyase · PMID 21661762 · 4 records
• Structural basis for the catalytic mechanism of the glycoside hydrolase family 3 isoprimeverose-producing oligoxyloglucan hydrolase from Aspergillus oryzae · PMID 35717558 · 5 records
• Structural basis for the enantiospecificities of R- and S-specific phenoxypropionate/alpha-ketoglutarate dioxygenases · PMID 16731970 · 17 records
• Structural basis for the erythro-stereospecificity of the L-arginine oxygenase VioC in viomycin biosynthesis · PMID 19490124 · 3 records
• Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10 · PMID 18087047 · 18 records
• Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization · PMID 16401075 · 24 records
• Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition · PMID 29891918 · 10 records
• Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate · PMID 26121039 · 5 records
• Structural basis for the substrate specificity of a Bacillus 1,3-1,4-beta-glucanase · PMID 16483609 · 17 records
• Structural basis for the substrate specificity of a novel β-N-acetylhexosaminidase StrH protein from Streptococcus pneumoniae R6 · PMID 22013074 · 22 records
• Structural basis for the synthesis of the core 1 structure by C1GalT1 · PMID 35504880 · 14 records
• Structural basis of D-DOPA oxidation by D-amino acid oxidase: alternative pathway for dopamine biosynthesis · PMID 17303072 · 4 records
• Structural basis of enzyme activity regulation by the propeptide of l-lysine α-oxidase precursor from Trichoderma viride · PMID 33554108 · 2 records
• Structural basis of Fumosorinone-mediated allosteric inhibition of PTP1B for cancer immunotherapy · PMID 42209755 · 3 records
• Structural basis of glyphosate resistance resulting from the double mutation Thr97 -> Ile and Pro101 -> Ser in 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli · PMID 19211556 · 8 records
• Structural basis of hematopoietic prostaglandin D synthase activity elucidated by site-directed mutagenesis · PMID 10871602 · 24 records
• Structural basis of L-glucose oxidation by scyllo-inositol dehydrogenase: Implications for a novel enzyme subfamily classification · PMID 29799855 · 4 records
• Structural basis of lipid binding for the membrane-embedded tetraacyldisaccharide-1-phosphate 4'-kinase LpxK · PMID 25023290 · 15 records
• Structural basis of methotrexate and pemetrexed action on serine hydroxymethyltransferases revealed using plant models · PMID 31873125 · 20 records
• Structural basis of strict substrate recognition of l-lysine α-oxidase from Trichoderma viride · PMID 32894626 · 9 records
• Structural basis of substrate recognition by hematopoietic tyrosine phosphatase · PMID 19053285 · 4 records
• Structural basis of substrate recognition in human nicotinamide N-methyltransferase · PMID 21823666 · 8 records
• Structural basis of substrate specificity and selectivity of murine cytosolic 5'-nucleotidase III · PMID 22925580 · 8 records
• Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase · PMID 19546224 · 13 records
• Structural basis of the ferrous iron specificity of the yeast ferroxidase, Fet3p · PMID 17042492 · 14 records
• Structural basis of the stereospecificity of bacterial B12-dependent 2-hydroxyisobutyryl-CoA mutase · PMID 25720495 · 18 records
• Structural characteristics of the nonallosteric human cytosolic malic enzyme · PMID 24998673 · 60 records
• Structural Characterization and Directed Evolution of a Novel Acetyl Xylan Esterase Reveals Thermostability Determinants of the Carbohydrate Esterase 7 Family · PMID 29453256 · 14 records
• Structural Characterization and Engineering of a GH134 β-Mannanase from Aspergillus nidulans for Enhancement of Activity and Stability · PMID 42715962 · 4 records
• Structural characterization and function determination of a nonspecific carboxylate esterase from the amidohydrolase superfamily with a promiscuous ability to hydrolyze methylphosphonate esters · PMID 24832101 · 33 records
• Structural characterization and functional analysis of cystathionine β-synthase: an enzyme involved in the reverse transsulfuration pathway of Bacillus anthracis · PMID 28921884 · 9 records
• Structural characterization and reversal of the natural organophosphate resistance of a D-type esterase, Saccharomyces cerevisiae S-formylglutathione hydrolase · PMID 18707125 · 25 records
• Structural Characterization of Functionally Important Chloride Binding Sites in the Marine Vibrio Alkaline Phosphatase · PMID 36194497 · 14 records
• Structural characterization of pyruvic oxime dioxygenase, a key enzyme in heterotrophic nitrification · PMID 39772954 · 10 records
• Structural characterization of the catalytic site of a Nilaparvata lugens delta-class glutathione transferase · PMID 25497345 · 16 records
• Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase · PMID 20565114 · 3 records
• Structural Comparison of a Promiscuous and a Highly Specific Sucrose 6^F-Phosphate Phosphorylase · PMID 31405215 · 9 records
• Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development · PMID 33139328 · 10 records
• Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80 · PMID 29581307 · 7 records
• Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases · PMID 17185228 · 3 records
• Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily · PMID 31283204 · 9 records
• Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs · PMID 12742017 · 48 records
• Structural determinants in streptococcal unsaturated glucuronyl hydrolase for recognition of glycosaminoglycan sulfate groups · PMID 21147778 · 17 records
• Structural determinants of an insect beta-N-Acetyl-D-hexosaminidase specialized as a chitinolytic enzyme · PMID 21106526 · 11 records
• Structural determinants of specificity and catalytic mechanism in mammalian 25-kDa thiamine triphosphatase · PMID 23707715 · 12 records
• Structural determinants of substrate recognition in the HAD superfamily member D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB) · PMID 20050614 · 11 records
• Structural determinants of the 5'-methylthioinosine specificity of Plasmodium purine nucleoside phosphorylase · PMID 24416224 · 38 records
• Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases · PMID 10620324 · 26 records
• Structural dissection and high-throughput screening of mannosylglycerate synthase · PMID 15951819 · 11 records
• Structural diversity and substrate preferences of three tannase enzymes encoded by the anaerobic bacterium Clostridium butyricum · PMID 35202648 · 14 records
• Structural diversity of angiotensin-converting enzyme · PMID 16403023 · 18 records
• Structural elements in dextran glucosidase responsible for high specificity to long chain substrate · PMID 16503208 · 39 records
• Structural elucidation and characterization of GH29A α-l-fucosidases and the effect of pH on their transglycosylation · PMID 39658312 · 5 records
• Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa · PMID 35921328 · 12 records
• Structural enzymological studies of 2-enoyl thioester reductase of the human mitochondrial FAS II pathway: new insights into its substrate recognition properties · PMID 18479707 · 21 records
• Structural enzymology of a Fusarium graminearum aldehyde oxidase reveals a distinct active-site and reactivity versus its paralog galactose oxidase · PMID 41883256 · 21 records
• Structural features of Aspergillus niger β-galactosidase define its activity against glycoside linkages · PMID 28391618 · 8 records
• Structural flexibility of the methanogenic-type seryl-tRNA synthetase active site and its implication for specific substrate recognition · PMID 18422966 · 22 records
• Structural insight into _D-xylose utilization by xylose reductase from Scheffersomyces stipitis · PMID 30487522 · 8 records
• Structural insight into the catalytic mechanism of the bifunctional enzyme l-fucokinase/GDP-fucose pyrophosphorylase · PMID 39993526 · 26 records
• Structural insight into the mechanism of substrate specificity and catalytic activity of an HD-domain phosphohydrolase: the 5'-deoxyribonucleotidase YfbR from Escherichia coli · PMID 18353368 · 11 records
• Structural insight into the oxidation of sinapic acid by CotA laccase · PMID 25799944 · 9 records
• Structural insight into the reaction mechanism and evolution of cytokinin biosynthesis · PMID 18258747 · 13 records
• Structural insight into the unique substrate binding mechanism and flavin redox state of UDP-galactopyranose mutase from Aspergillus fumigatus · PMID 22334662 · 4 records
• Structural Insights into a Bifunctional Peptide Methionine Sulfoxide Reductase MsrA/B Fusion Protein from Helicobacter pylori · PMID 33807684 · 14 records
• Structural insights into catalytic promiscuity of chalcone synthase from Glycine max (L.) Merr.: Coenzyme A-induced alteration of product specificity · PMID 38735137 · 4 records
• Structural Insights into Catalytic Versatility of the Flavin-dependent Hydroxylase (HpaB) from Escherichia coli · PMID 31068633 · 24 records
• Structural insights into catalytical capability for CPT11 hydrolysis and substrate specificity of a novel marine microbial carboxylesterase, E93 · PMID 36756200 · 29 records
• Structural Insights Into CO₂ Transport Pathways in a W-Formate Dehydrogenase: Structural Basis for CO₂ Reduction · PMID 41787858 · 10 records
• Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium · PMID 22796868 · 8 records
• Structural insights into enzymatic activity and substrate specificity determination by a single amino acid in nitrilase from Syechocystis sp. PCC6803 · PMID 25450592 · 18 records
• Structural insights into interdomain interactions in Entamoeba histolytica APS kinase · PMID 42212241 · 8 records
• Structural Insights into l-Tryptophan Dehydrogenase from a Photoautotrophic Cyanobacterium, Nostoc punctiforme · PMID 27815281 · 18 records
• Structural Insights into Malic Enzyme Variants Favoring an Unnatural Redox Cofactor · PMID 33523590 · 18 records
• Structural insights into marine carbohydrate degradation by family GH16 κ-carrageenases · PMID 29030427 · 8 records
• Structural insights into ortho-aminophenol oxidases: kinetic and crystallographic characterization of SmNspF and SgGriF · PMID 41836335 · 17 records
• Structural insights into rice BGlu1 beta-glucosidase oligosaccharide hydrolysis and transglycosylation · PMID 18308333 · 15 records
• Structural insights into SETD3-mediated histidine methylation on β-actin · PMID 30785395 · 18 records
• Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution · PMID 20826162 · 14 records
• Structural insights into the broad substrate specificity of carboxypeptidase T from Thermoactinomyces vulgaris · PMID 25619204 · 16 records
• Structural insights into the cofactor-assisted substrate recognition of yeast methylglyoxal/isovaleraldehyde reductase Gre2 · PMID 24879127 · 8 records
• Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases · PMID 22522127 · 8 records
• Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase · PMID 29576532 · 7 records
• Structural insights into the low pH adaptation of a unique carboxylesterase from Ferroplasma: altering the pH optima of two carboxylesterases · PMID 25043762 · 11 records
• Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis · PMID 16541109 · 10 records
• Structural insights into the mechanism of four-coordinate Cob(II)alamin formation in the active site of the Salmonella enterica ATP:Co(I)rrinoid adenosyltransferase enzyme: critical role of residues… · PMID 23148601 · 38 records
• Structural Insights into the Nonmutagenicity of 2-Haloacetophenone · PMID 40142039 · 2 records
• Structural insights into the novel diadenosine 5',5‴-P¹,P⁴-tetraphosphate phosphorylase from Mycobacterium tuberculosis H37Rv · PMID 21565198 · 5 records
• Structural Insights into the Substrate Recognition of Ginsenoside Glycosyltransferase Pq3-O-UGT2 · PMID 39887940 · 44 records
• Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria · PMID 18167146 · 21 records
• Structural insights into the substrate specificity of (s)-ureidoglycolate amidohydrolase and its comparison with allantoate amidohydrolase · PMID 25020232 · 5 records
• Structural insights into the Thermus thermophilus ADP-ribose pyrophosphatase mechanism via crystal structures with the bound substrate and metal · PMID 15210687 · 10 records
• Structural insights into ubiquitin recognition by USP15 revealed through a covalent activity-based probe · PMID 42259887 · 2 records
• Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator. Implications for the design of low molecular weight substrates and inhibitors · PMID 9268299 · 29 records
• Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase · PMID 29307486 · 6 records
• Structural principles of the broad substrate specificity of Thermoactinomyces vulgaris carboxypeptidase T--role of amino acid residues at positions 260 and 262 · PMID 18515300 · 14 records
• Structural studies of cinnamoyl-CoA reductase and cinnamyl-alcohol dehydrogenase, key enzymes of monolignol biosynthesis · PMID 25217505 · 12 records
• Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase · PMID 15007066 · 4 records
• Structural study reveals that Ser-354 determines substrate specificity on human histidine decarboxylase · PMID 22767596 · 4 records
• Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 · PMID 29791483 · 62 records
• Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies · PMID 29309127 · 7 records
• Structural, immunological and kinetic comparisons of NADP-dependent malate dehydrogenases from spinach (C3) and corn (C4) chloroplasts · PMID 3948869 · 6 records
• Structural, kinetic, and calorimetric characterization of the cold-active phosphoglycerate kinase from the antarctic Pseudomonas sp. TACII18 · PMID 10753921 · 8 records
• Structural, kinetic, and evolutionary peculiarities of HISN3, a plant 5'-ProFAR isomerase · PMID 39186852 · 2 records
• Structural, Mechanistic, and Functional Insights into an Arthrobacter nicotinovorans Molybdenum Hydroxylase Involved in Nicotine Degradation · PMID 34299660 · 9 records
• Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase · PMID 16279783 · 20 records
• Structural, Thermodynamic and Enzymatic Characterization of N,N-Diacetylchitobiose Deacetylase from Pyrococcus chitonophagus · PMID 36555375 · 17 records
• Structurally informed site-directed mutagenesis of a stereochemically promiscuous aldolase to afford stereochemically complementary biocatalysts · PMID 20684556 · 6 records
• Structure and activity of a phosphinothricin N-acetyltransferase (PSPTO_3321) from Pseudomonas syringae pv. tomato DC3000 · PMID 40054337 · 5 records
• Structure and activity of human mitochondrial peptide deformylase, a novel cancer target · PMID 19236878 · 18 records
• Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae · PMID 20427268 · 21 records
• Structure and activity of the NAD(P)+-dependent succinate semialdehyde dehydrogenase YneI from Salmonella typhimurium · PMID 23229889 · 18 records
• Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme · PMID 21548881 · 6 records
• Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase · PMID 29791083 · 7 records
• Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant · PMID 27486859 · 6 records
• Structure and catalysis of acylaminoacyl peptidase: closed and open subunits of a dimer oligopeptidase · PMID 21084296 · 30 records
• Structure and catalytic mechanism of 3-ketosteroid-Delta4-(5α)-dehydrogenase from Rhodococcus jostii RHA1 genome · PMID 22833669 · 3 records
• Structure and catalytic mechanism of a SET domain protein methyltransferase · PMID 12372303 · 8 records
• Structure and catalytic mechanism of LigI: insight into the amidohydrolase enzymes of cog3618 and lignin degradation · PMID 22475079 · 14 records
• Structure and catalytic mechanism of the evolutionarily unique bacterial chalcone isomerase · PMID 25849401 · 8 records
• Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase · PMID 32591529 · 18 records
• Structure and characterisation of CMP-Kdn synthetase from the haptophyte microalgae Prymnesium parvum · PMID 41756713 · 6 records
• Structure and characterization of amidase from Rhodococcus sp. N-771: Insight into the molecular mechanism of substrate recognition · PMID 19819352 · 4 records
• Structure and engineering of L-arabinitol 4-dehydrogenase from Neurospora crassa · PMID 20655316 · 8 records
• Structure and enzymology of glutaminase S482C and H461L variants associated with excess brain glutamate and neurological disease · PMID 42055345 · 6 records
• Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase · PMID 26175150 · 4 records
• Structure and function of 2,3-dimethylmalate lyase, a PEP mutase/isocitrate lyase superfamily member · PMID 19133276 · 18 records
• Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax · PMID 11292348 · 7 records
• Structure and function of an ancestral-type β-decarboxylating dehydrogenase from Thermococcus kodakarensis · PMID 27831491 · 36 records
• Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase · PMID 26734760 · 8 records
• Structure and Function of Honeybee α-Amylase of Glycoside Hydrolase Family 13 Subfamily 15 · PMID 42588464 · 27 records
• Structure and function of nucleoside hydrolases from Physcomitrella patens and maize catalyzing the hydrolysis of purine, pyrimidine, and cytokinin ribosides · PMID 24170203 · 42 records
• Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation · PMID 24361046 · 19 records
• Structure and function of Salmonella typhimurium orotate phosphoribosyltransferase: protein complementation reveals shared active sites · PMID 7545006 · 12 records
• Structure and Function of the Acetylpolyamine Amidohydrolase from the Deep Earth Halophile Marinobacter subterrani · PMID 31436969 · 5 records
• Structure and function of the engineered multicopper oxidase CueO from Escherichia coli--deletion of the methionine-rich helical region covering the substrate-binding site · PMID 17804014 · 8 records
• Structure and function of the glutamine phosphoribosylpyrophosphate amidotransferase glutamine site and communication with the phosphoribosylpyrophosphate site · PMID 8663035 · 40 records
• Structure and function of YcnD from Bacillus subtilis, a flavin-containing oxidoreductase · PMID 16229462 · 8 records
• Structure and functional characterization of a bile acid 7α dehydratase BaiE in secondary bile acid synthesis · PMID 26650892 · 8 records
• Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae · PMID 17059210 · 2 records
• Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity · PMID 26364932 · 4 records
• Structure and kinetic analysis of H2S production by human mercaptopyruvate sulfurtransferase · PMID 23698001 · 14 records
• Structure and kinetic properties of human d-aspartate oxidase, the enzyme-controlling d-aspartate levels in brain · PMID 31914658 · 25 records
• Structure and kinetics of phosphonopyruvate hydrolase from Variovorax sp. Pal2: new insight into the divergence of catalysis within the PEP mutase/isocitrate lyase superfamily · PMID 16981709 · 4 records
• Structure and mechanism of a cysteine sulfinate desulfinase engineered on the aspartate aminotransferase scaffold · PMID 22138634 · 5 records
• Structure and mechanism of an inverting alkylsulfatase from Pseudomonas sp. DSM6611 specific for secondary alkyl sulfates · PMID 23061549 · 12 records
• Structure and mechanism of benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633, a member of the Class 3 aldehyde dehydrogenase superfamily · PMID 28338942 · 9 records
• Structure and mechanism of chitin deacetylase from the fungal pathogen Colletotrichum lindemuthianum · PMID 16878976 · 4 records
• Structure and mechanism of copper- and nickel-substituted analogues of metallo-beta-lactamase L1 · PMID 19228020 · 18 records
• Structure and mechanism of glutamate racemase from Aquifex pyrophilus · PMID 10331867 · 6 records
• Structure and mechanism of GumK, a membrane-associated glucuronosyltransferase · PMID 18596046 · 20 records
• Structure and mechanism of human diacylglycerol O-acyltransferase 1 · PMID 32433610 · 13 records
• Structure and Mechanism of Isopropylmalate Dehydrogenase from Arabidopsis thaliana: INSIGHTS ON LEUCINE AND ALIPHATIC GLUCOSINOLATE BIOSYNTHESIS · PMID 27137927 · 12 records
• Structure and mechanism of PhnP, a phosphodiesterase of the carbon-phosphorus lyase pathway · PMID 21830807 · 19 records
• Structure and mechanism of soybean ATP sulfurylase and the committed step in plant sulfur assimilation · PMID 24584934 · 42 records
• Structure and mechanism of spermidine synthases · PMID 17585781 · 18 records
• Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei · PMID 20825170 · 14 records
• Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM · PMID 18502766 · 20 records
• Structure and mutational analysis of a plant mitochondrial nucleoside diphosphate kinase. Identification of residues involved in serine phosphorylation and oligomerization · PMID 15466238 · 6 records
• Structure and properties of the putrescine carbamoyltransferase of Streptococcus faecalis · PMID 116850 · 11 records
• Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an antiparasitic drug target · PMID 22117061 · 6 records
• Structure and Reaction Mechanism of the LigJ Hydratase: An Enzyme Critical for the Bacterial Degradation of Lignin in the Protocatechuate 4,5-Cleavage Pathway · PMID 30207699 · 4 records
• Structure and reactivity of Bacillus subtilis MenD catalyzing the first committed step in menaquinone biosynthesis · PMID 20600129 · 18 records
• Structure and spectroscopy of the periplasmic cytochrome c nitrite reductase from Escherichia coli · PMID 11863430 · 2 records
• Structure and substrate specificity of the pyrococcal coenzyme A disulfide reductases/polysulfide reductases (CoADR/Psr): implications for S(0)-based respiration and a sulfur-dependent antioxidant… · PMID 23530771 · 11 records
• Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis · PMID 29317628 · 4 records
• Structure of 6-oxo camphor hydrolase H122A mutant bound to its natural product, (2S,4S)-alpha-campholinic acid: mutant structure suggests an atypical mode of transition state binding for a crotonase… · PMID 15138275 · 6 records
• Structure of a bacterial α-1,2-glucosidase defines mechanisms of hydrolysis and substrate specificity in GH65 family hydrolases · PMID 34728215 · 7 records
• Structure of a PL17 family alginate lyase demonstrates functional similarities among exotype depolymerases · PMID 24478312 · 7 records
• Structure of an endogalactosylceramidase from Rhodococcus hoagii 103S reveals the molecular basis of its substrate specificity · PMID 31557527 · 10 records
• Structure of Arabidopsis dehydroquinate dehydratase-shikimate dehydrogenase and implications for metabolic channeling in the shikimate pathway · PMID 16784230 · 19 records
• Structure of dihydropyrimidinase from Sinorhizobium meliloti CECT4114: new features in an amidohydrolase family member · PMID 19895890 · 16 records
• Structure of human dCK suggests strategies to improve anticancer and antiviral therapy · PMID 12808445 · 8 records
• Structure of NADP(+)-dependent glutamate dehydrogenase from Escherichia coli--reflections on the basis of coenzyme specificity in the family of glutamate dehydrogenases · PMID 23879525 · 11 records
• Structure of PhnP, a phosphodiesterase of the carbon-phosphorus lyase pathway for phosphonate degradation · PMID 19366688 · 8 records
• Structure of the D142N mutant of the family 18 chitinase ChiB from Serratia marcescens and its complex with allosamidin · PMID 14726210 · 14 records
• Structure of the flavoprotein tryptophan 2-monooxygenase, a key enzyme in the formation of galls in plants · PMID 23521653 · 3 records
• Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate · PMID 19237748 · 10 records
• Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution · PMID 11514561 · 3 records
• Structure of the human aminopeptidase XPNPEP3 and comparison of its in vitro activity with Icp55 orthologs: Insights into diverse cellular processes · PMID 28476889 · 24 records
• Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs · PMID 24992307 · 16 records
• Structure prediction and active site analysis of the metal binding determinants in gamma -glutamylcysteine synthetase · PMID 11527962 · 22 records
• Structure, characterisation and application of an unspecific peroxygenase from Daldinia childiae · PMID 42328014 · 1 record
• Structure, function, and mechanism of the phenylacetate pathway hot dog-fold thioesterase PaaI · PMID 16464851 · 36 records
• Structure, interactions and action of Mycobacterium tuberculosis 3-hydroxyisobutyric acid dehydrogenase · PMID 29959185 · 9 records
• Structure, kinetics, and mechanism of Pseudomonas putida sulfoquinovose dehydrogenase, the first enzyme in the sulfoglycolytic Entner-Doudoroff pathway · PMID 39840830 · 4 records
• Structure, mechanism, and substrate profile for Sco3058: the closest bacterial homologue to human renal dipeptidase · PMID 20000809 · 28 records
• Structure, molecular evolution, and hydrolytic specificities of largemouth bass pepsins · PMID 26627128 · 15 records
• Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum · PMID 14555659 · 3 records
• Structure-activity analysis of cathepsin K/chondroitin 4-sulfate interactions · PMID 21193413 · 12 records
• Structure-activity relationship of a cold-adapted purine nucleoside phosphorylase by site-directed mutagenesis · PMID 22579392 · 8 records
• Structure-activity relationship study shows versatility in substrate specificity for heterodisulfide reductase in methanogenic archaea · PMID 42283392 · 5 records
• Structure-activity relationships and thermal stability of human glutathione transferase P1-1 governed by the H-site residue 105 · PMID 9600848 · 24 records
• Structure-activity relationships in catalytic amyloids · PMID 41422714 · 14 records
• Structure-activity studies of the inhibition of FabI, the enoyl reductase from Escherichia coli, by triclosan: kinetic analysis of mutant FabIs · PMID 12693936 · 12 records
• Structure-based activity prediction for an enzyme of unknown function · PMID 17603473 · 5 records
• Structure-based alteration of substrate specificity and catalytic activity of sulfite oxidase from sulfite oxidation to nitrate reduction · PMID 22263579 · 127 records
• Structure-based characterization of canine-human chimeric uricases and its evolutionary implications · PMID 22481018 · 5 records
• Structure-Based Design and Mechanistic Insight for Enhanced Catalytic Activity of Aldo/Keto Reductase AKR13B3 from Devosia A6-243 Toward T-2 Toxin · PMID 42043022 · 4 records
• Structure-based dissection of the active site chemistry of leukotriene A4 hydrolase: implications for M1 aminopeptidases and inhibitor design · PMID 18804029 · 6 records
• Structure-based engineering of Alcaligenes xylosoxidans copper-containing nitrite reductase enhances intermolecular electron transfer reaction with pseudoazurin · PMID 15475344 · 9 records
• Structure-Based Engineering of Phanerochaete chrysosporium Alcohol Oxidase for Enhanced Oxidative Power toward Glycerol · PMID 30272958 · 18 records
• Structure-based engineering of strictosidine synthase: auxiliary for alkaloid libraries · PMID 17884630 · 14 records
• Structure-based functionality of a multi-domain periplasmic chitodextrinase from marine bacterium Vibrio cholerae · PMID 42480705 · 1 record
• Structure-based identification of a novel NTPase from Methanococcus jannaschii · PMID 10404228 · 7 records
• Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase · PMID 12467706 · 12 records
• Structure-Based Redesign of a Self-Sufficient Flavin-Containing Monooxygenase towards Indigo Production · PMID 31817552 · 10 records
• Structure-based redesign of cofactor binding in putrescine oxidase · PMID 21486042 · 8 records
• Structure-based virtual screening aids the identification of glycosyltransferases in the biosynthesis of salidroside · PMID 39932927 · 1 record
• Structure-function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds · PMID 30814248 · 17 records
• Structure-function analysis of 2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphatase defines specificity elements in type C0 haloalkanoate dehalogenase family members · PMID 18986982 · 9 records
• Structure-function analysis of a new PL17 oligoalginate lyase from the marine bacterium Zobellia galactanivorans DsijT · PMID 34184062 · 7 records
• Structure-function analysis of human l-prostaglandin D synthase bound with fatty acid molecules · PMID 20667974 · 12 records
• Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: amino acid residues responsible for species-based difference of CYP24A1 between humans and rats · PMID 16617161 · 9 records
• Structure-function relationship of assimilatory nitrite reductases from the leaf and root of tobacco based on high-resolution structures · PMID 22238192 · 7 records
• Structure-Function Relationship of the β-Hairpin of Thermus thermophilus HB27 Laccase · PMID 39859450 · 28 records
• Structure-function relationship of Vibrio harveyi NADPH-flavin oxidoreductase FRP: essential residues Lys167 and Arg15 for NADPH binding · PMID 22650604 · 8 records
• Structure-function relationships for Schizophyllum commune trehalose phosphorylase and their implications for the catalytic mechanism of family GT-4 glycosyltransferases · PMID 16640506 · 14 records
• Structure-function relationships in Escherichia coli adenylate cyclase · PMID 18620542 · 15 records
• Structure-function studies of arginine at position 276 in CTX-M beta-lactamases · PMID 18281307 · 14 records
• Structure-function studies of two novel UDP-GlcNAc C6 dehydratases/C4 reductases. Variation from the SYK dogma · PMID 12004063 · 7 records
• Structure-Functional Examination of Novel Ribonucleoside Hydrolase C (RihC) from Limosilactobacillus reuteri LR1 · PMID 38203708 · 9 records
• Structure-guided alteration of coenzyme specificity of formate dehydrogenase by saturation mutagenesis to enable efficient utilization of NADP+ · PMID 18616465 · 18 records
• Structure-Guided Biochemical Analysis of Quorum Signal Synthase Specificities · PMID 32356962 · 28 records
• Structure-guided design of a methyl donor cofactor that controls a viral histone H3 lysine 27 methyltransferase activity · PMID 21958314 · 11 records
• Structure-Guided Engineering of α-Keto Acid Decarboxylase for the Production of Higher Alcohols at Elevated Temperature · PMID 29953730 · 14 records
• Structure-guided function discovery of an NRPS-like glycine betaine reductase for choline biosynthesis in fungi · PMID 31061132 · 10 records
• Structure-guided mutagenesis for the improvement of substrate specificity of Bacillus megaterium glucose 1-dehydrogenase IV · PMID 22804868 · 16 records
• Structure-guided protein engineering of ammonia lyase for efficient synthesis of sterically bulky unnatural amino acids · PMID 38650190 · 6 records
• Structure-guided surface engineering to improve the catalytic activity of ethylene-forming enzyme · PMID 42238545 · 6 records
• Structure-oriented substrate specificity engineering of aldehyde-deformylating oxygenase towards aldehydes carbon chain length · PMID 27588038 · 29 records
• Structure/function of human type 1 3beta-hydroxysteroid dehydrogenase: An intrasubunit disulfide bond in the Rossmann-fold domain and a Cys residue in the active site are critical for substrate and… · PMID 17624763 · 34 records
• Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase · PMID 12832414 · 13 records
• Structure/function relationships responsible for the kinetic differences between human type 1 and type 2 3beta-hydroxysteroid dehydrogenase and for the catalysis of the type 1 activity · PMID 12205101 · 19 records
• Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases · PMID 30536999 · 19 records
• Structures of activated fructose-1,6-bisphosphatase from Escherichia coli. Coordinate regulation of bacterial metabolism and the conservation of the R-state · PMID 17314096 · 3 records
• Structures of bacterial kynurenine formamidase reveal a crowded binuclear zinc catalytic site primed to generate a potent nucleophile · PMID 24942958 · 3 records
• Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds · PMID 12614151 · 10 records
• Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities · PMID 12637497 · 10 records
• Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors · PMID 17727341 · 6 records
• Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism · PMID 23050861 · 5 records
• Studies of a novel cysteine sulfoxide lyase from Petiveria alliacea: the first heteromeric alliinase · PMID 19789290 · 12 records
• Studies of catalysis by ribonuclease U2. Steady-state kinetics for transphosphorylation of oligonucleotide and synthetic substrates · PMID 7074019 · 18 records
• Studies of rabbit brain, intestine and liver guanine aminohydrolase · PMID 6713831 · 27 records
• Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant · PMID 15109252 · 25 records
• Studies of the regulation and reaction mechanism of the carbamyl phosphate synthetase and aspartate transcarbamylase of bakers' yeast · PMID 182284 · 2 records
• Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme · PMID 20124700 · 36 records
• Studies on active site mutants of P. falciparum adenylosuccinate synthetase: insights into enzyme catalysis and activation · PMID 20654742 · 22 records
• Studies on D-tetrose metabolism. Crystallization and properties of D-erythrulose reductase from chicken liver · PMID 7358641 · 4 records
• Studies on structure-function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway · PMID 12752452 · 12 records
• Studies on the kinetic mechanism of pig kidney D-amino acid oxidase by site-directed mutagenesis of tyrosine 224 and tyrosine 228 · PMID 7989339 · 30 records
• Studies on the regioselectivity and kinetics of the action of trypsin on proinsulin and its derivatives using mass spectrometry · PMID 22982989 · 8 records
• Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics · PMID 28852116 · 6 records
• Studies on the subsite specificity of rat nardilysin (N-arginine dibasic convertase) · PMID 10764809 · 45 records
• Studies on the substrate specificity of Escherichia coli galactokinase · PMID 12816414 · 6 records
• Studies on the substrate specificity of hexosaminidase A and B from liver · PMID 4346630 · 15 records
• Study of Class I and Class III Polyhydroxyalkanoate (PHA) Synthases with Substrates Containing a Modified Side Chain · PMID 26974339 · 9 records
• Study of the arrangement of the functional domains along the yeast cytoplasmic aspartyl-tRNA synthetase · PMID 2647492 · 33 records
• Study of the mode of action of endopolygalacturonase from Fusarium moniliforme · PMID 11410340 · 6 records
• Study of the roles of Arg-104 and Arg-225 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by site-directed mutagenesis · PMID 7619077 · 16 records
• Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms · PMID 16118205 · 12 records
• Subcellular distribution and properties of acyl/alkyl dihydroxyacetone phosphate reductase in rodent livers · PMID 3954368 · 9 records
• SUBCELLULAR DISTRIBUTION AND PROPERTIES OF HEPATIC GLUCOSE DEHYDROGENASES OF SELECTED VERTEBRATES · PMID 14342292 · 15 records
• Subcloning of the enterobactin biosynthetic gene entB: expression, purification, characterization, and substrate specificity of isochorismatase · PMID 2139796 · 6 records
• Subcloning, characterization, and affinity labeling of Escherichia coli glycinamide ribonucleotide transformylase · PMID 2185839 · 12 records
• Subsite preferences of pepstatin-insensitive carboxyl proteinases from bacteria · PMID 9880800 · 88 records
• Subsite preferences of pepstatin-insensitive carboxyl proteinases from prokaryotes: kumamolysin, a thermostable pepstatin-insensitive carboxyl proteinase · PMID 10965051 · 67 records
• Subsite specificity (S3, S2, S1', S2' and S3') of oligopeptidase B from Trypanosoma cruzi and Trypanosoma brucei using fluorescent quenched peptides: comparative study and identification of specific… · PMID 12737623 · 142 records
• Subsite structure of the endo-type chitin deacetylase from a deuteromycete, Colletotrichum lindemuthianum: an investigation using steady-state kinetic analysis and MS · PMID 12775215 · 7 records
• Subsites of trypsin active site favor catalysis or substrate binding · PMID 11779198 · 46 records
• Substituent effects during the rat liver aldehyde dehydrogenase catalyzed oxidation of aromatic aldehydes · PMID 3300781 · 27 records
• Substituents effects on activity of kynureninase from Homo sapiens and Pseudomonas fluorescens · PMID 23791867 · 15 records
• Substituted aryl malonamates as new serine beta-lactamase substrates: structure-activity studies · PMID 19932622 · 22 records
• Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM) · PMID 18952446 · 57 records
• Substitution of a Surface-Exposed Residue Involved in an Allosteric Network Enhances Tryptophan Synthase Function in Cells · PMID 34124159 · 6 records
• Substitution of Arginine 120 in Human D-Amino Acid Oxidase Favors FAD-Binding and Nuclear Mistargeting · PMID 31799256 · 6 records
• Substitution of cysteine for selenocysteine in the catalytic center of type III iodothyronine deiodinase reduces catalytic efficiency and alters substrate preference · PMID 12746313 · 19 records
• Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase · PMID 20043918 · 13 records
• Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction · PMID 15078097 · 4 records
• Substitutions at the cofactor phosphate-binding site of a clostridial alcohol dehydrogenase lead to unexpected changes in substrate specificity · PMID 26034298 · 24 records
• Substitutions of S101 decrease proton and hydride transfers in the oxidation of betaine aldehyde by choline oxidase · PMID 29029877 · 8 records
• Substrate (aglycone) specificity of human cytosolic beta-glucosidase · PMID 12667141 · 21 records
• Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase? · PMID 16142893 · 10 records
• Substrate analogues as probes of the catalytic mechanism of L-mandelate dehydrogenase from Rhodotorula graminis · PMID 8110205 · 11 records
• Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum · PMID 9497046 · 25 records
• Substrate and inhibitor specificity of Mycobacterium avium dihydrofolate reductase · PMID 17542991 · 20 records
• Substrate and metabolic promiscuities of d-altronate dehydratase family proteins involved in non-phosphorylative d-arabinose, sugar acid, l-galactose and l-fucose pathways from bacteria · PMID 30985034 · 50 records
• Substrate and metal ion promiscuity in mannosylglycerate synthase · PMID 21288903 · 42 records
• Substrate and pH-Dependent Kinetic Profile of 3-Mercaptopropionate Dioxygenase from Pseudomonas aeruginosa · PMID 26878277 · 23 records
• Substrate and positional specificity of feruloyl esterases for monoferuloylated and monoacetylated 4-nitrophenyl glycosides · PMID 16901567 · 23 records
• Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase · PMID 15447632 · 15 records
• Substrate and Stereochemical Control of Peptidoglycan Cross-Linking by Transpeptidation by Escherichia coli PBP1B · PMID 32048840 · 14 records
• Substrate binding and catalytic mechanism of a barley beta-D-Glucosidase/(1,4)-beta-D-glucan exohydrolase · PMID 9556600 · 8 records
• Substrate binding determinants of Trypanosoma brucei gamma-glutamylcysteine synthetase · PMID 11851421 · 20 records
• Substrate cooperativity shapes competitive inhibitor responses in mycobacterial inosine 5'-monophosphate dehydrogenase · PMID 41495879 · 8 records
• Substrate determinants of the course of tartrate dehydrogenase-catalyzed reactions · PMID 7779796 · 13 records
• Substrate diffusion and oxidation in GMC oxidoreductases: an experimental and computational study on fungal aryl-alcohol oxidase · PMID 21375505 · 5 records
• Substrate discrimination by formamidopyrimidine-DNA glycosylase: a mutational analysis · PMID 14607836 · 18 records
• Substrate discrimination by the human GTP fucose pyrophosphorylase · PMID 16086588 · 29 records
• Substrate diversity of herpes simplex virus thymidine kinase. Impact Of the kinematics of the enzyme · PMID 10542226 · 10 records
• Substrate hydrolysis by matrix metalloproteinase-9 · PMID 11279151 · 22 records
• Substrate inactivation of bacterial L-aspartate α-decarboxylase from Corynebacterium jeikeium K411 and improvement of molecular stability by saturation mutagenesis · PMID 30923994 · 5 records
• Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L · PMID 22234330 · 8 records
• Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center · PMID 1396557 · 13 records
• Substrate interaction defects in histidyl-tRNA synthetase linked to dominant axonal peripheral neuropathy · PMID 29235198 · 10 records
• Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs · PMID 21914723 · 10 records
• Substrate preference of carbamate hydrolase CehA reveals its environmental behavior · PMID 32835992 · 15 records
• Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change · PMID 23787140 · 4 records
• Substrate profiling of cyclohexylamine oxidase and its mutants reveals new biocatalytic potential in deracemization of racemic amines · PMID 23793344 · 18 records
• Substrate promiscuity of a rosmarinic acid synthase from lavender (Lavandula angustifolia L.) · PMID 21424826 · 20 records
• Substrate promiscuity of N-acetylhexosamine 1-kinases · PMID 21799473 · 8 records
• Substrate Recognition Analysis in an Ethyl Carbamate-Hydrolyzing Esterase and Semi-Rational Baijiu Flavor Preservation · PMID 42737361 · 2 records
• Substrate recognition and catalysis by the cofactor-independent dioxygenase DpgC · PMID 18004875 · 8 records
• Substrate recognition and catalysis by UCH-L1 · PMID 17144664 · 38 records
• Substrate Recognition and Catalytic Mechanism of the Phosphate Acyltransferase PlsX from Bacillus subtilis · PMID 32180316 · 29 records
• Substrate recognition and cleavage by mucin degrading O-glycopeptidases from the gut microbe Bacteroides caccae · PMID 42248462 · 23 records
• Substrate recognition and mechanism revealed by ligand-bound polyphosphate kinase 2 structures · PMID 29531036 · 10 records
• Substrate recognition and selectivity of peptide deformylase. Similarities and differences with metzincins and thermolysin · PMID 10373378 · 69 records
• Substrate recognition by a yeast 2'-phosphotransferase involved in tRNA splicing and by its Escherichia coli homolog · PMID 11705403 · 23 records
• Substrate recognition by the human fatty-acid synthase · PMID 16215233 · 27 records
• Substrate recognition by β-ketoacyl-ACP synthases · PMID 22017312 · 26 records
• Substrate recognition mechanism of carboxypeptidase Y · PMID 11791720 · 12 records
• Substrate recognition mechanisms of ʟ-glutamate oxidase from Streptomyces sp. and its conversion to ʟ-tyrosine oxidase · PMID 41432352 · 11 records
• Substrate recognition properties of oligopeptidase B from Salmonella enterica serovar Typhimurium · PMID 12029050 · 49 records
• Substrate scope of a dehydrogenase from Sphingomonas species A1 and its potential application in the synthesis of rare sugars and sugar derivatives · PMID 29697194 · 18 records
• Substrate Selectivities of GH78 α-L-Rhamnosidases from Human Gut Bacteria on Dietary Flavonoid Glycosides · PMID 40076204 · 11 records
• Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase · PMID 20421396 · 15 records
• Substrate specificities and conformational flexibility of 3-ketosteroid 9α-hydroxylases · PMID 25049233 · 15 records
• Substrate specificities and kinetic properties of proteinase A from the yeast Saccharomyces cerevisiae and the development of a novel substrate · PMID 9644256 · 41 records
• Substrate specificities of 3-oxoacyl-CoA thiolase A and sterol carrier protein 2/3-oxoacyl-CoA thiolase purified from normal rat liver peroxisomes. Sterol carrier protein 2/3-oxoacyl-CoA thiolase is… · PMID 9325339 · 18 records
• Substrate specificities of caspase family proteases · PMID 9092497 · 46 records
• Substrate Specificities of DDX1: A Human DEAD-Box Protein · PMID 39895751 · 9 records
• Substrate specificities of deuterolysin from Aspergillus oryzae and electron paramagnetic resonance measurement of cobalt-substituted deuterolysin · PMID 12728984 · 10 records
• Substrate specificities of family 1 UGTs gained by domain swapping · PMID 19261311 · 43 records
• Substrate specificities of porcine and bovine enteropeptidases toward the peptide Val-(Asp)4-Lys-Ile-Val-Gly and its analogs · PMID 18323639 · 14 records
• Substrate specificities of recombinant mannan-binding lectin-associated serine proteases-1 and -2 · PMID 11527969 · 18 records
• Substrate specificities of two tau class glutathione transferases inducible by 2,4,6-trinitrotoluene in poplar · PMID 26026470 · 10 records
• Substrate specificity analysis and inhibitor design of homoisocitrate dehydrogenase · PMID 17116397 · 25 records
• Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes · PMID 17381426 · 28 records
• Substrate Specificity and Chemical Mechanism for the Reaction Catalyzed by Glutamine Kinase · PMID 30142271 · 5 records
• Substrate specificity and enantioselectivity of 4-hydroxyacetophenone monooxygenase · PMID 12514023 · 28 records
• Substrate specificity and expression of three 2,3-dihydroxybiphenyl 1,2-dioxygenases from Rhodococcus globerulus strain P6 · PMID 12700274 · 19 records
• Substrate specificity and identification of functional groups of homoserine kinase from Escherichia coli · PMID 8973190 · 38 records
• Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1) · PMID 21255593 · 9 records
• Substrate specificity and inhibitor sensitivity of rabbit 20α-hydroxysteroid dehydrogenase · PMID 23995665 · 64 records
• Substrate specificity and kinetic mechanism of Escherichia coli ribulokinase · PMID 11747300 · 15 records
• Substrate specificity and kinetic mechanism of purine nucleoside phosphorylase from Mycobacterium tuberculosis · PMID 19416718 · 14 records
• Substrate Specificity and Kinetic Mechanism of the NAD+-Dependent Deacylase from Mycobacterium tuberculosis, Rv1151c (Mt-Sirt) · PMID 42441379 · 46 records
• Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases · PMID 15274642 · 21 records
• Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases · PMID 16325466 · 84 records
• Substrate specificity and kinetic properties of pepstatin-insensitive carboxyl proteinase from Pseudomonas sp. No. 101 · PMID 1562589 · 18 records
• Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3 · PMID 20469888 · 65 records
• Substrate specificity and stereoselectivity of horse liver alcohol dehydrogenase. Kinetic evaluation of binding and activation parameters controlling the catalytic cycles of unbranched, acyclic… · PMID 1935957 · 24 records
• Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II · PMID 18620547 · 28 records
• Substrate specificity and structure-activity relationships of gentamicin acetyltransferase I. The dependence of antibiotic resistance upon substrate Vmax/Km values · PMID 681328 · 16 records
• Substrate specificity characterization of recombinant metallo oligo-peptidases thimet oligopeptidase and neurolysin · PMID 11284698 · 150 records
• Substrate specificity engineering of beta-mannosidase and beta-glucosidase from Pyrococcus by exchange of unique active site residues · PMID 11900558 · 26 records
• Substrate specificity in glycoside hydrolase family 10. Tyrosine 87 and leucine 314 play a pivotal role in discriminating between glucose and xylose binding in the proximal active site of… · PMID 10767281 · 34 records
• Substrate specificity of 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum: toward a bio-based production of adipic acid · PMID 21434666 · 13 records
• Substrate specificity of a mannose-6-phosphate isomerase from Bacillus subtilis and its application in the production of L-ribose · PMID 19447949 · 8 records
• Substrate specificity of a recombinant D-lyxose isomerase from Serratia proteamaculans that produces D-lyxose and D-mannose · PMID 20695994 · 4 records
• Substrate specificity of a tripeptidase as a metalloenzyme purified from Lactococcus lactis subsp. lactis biovar. diacetylactis ATCC 13675 · PMID 16233215 · 20 records
• Substrate specificity of an oxygen dependent sulfoxide synthase in ovothiol biosynthesis · PMID 23877651 · 6 records
• Substrate specificity of and product formation by muconate cycloisomerases: an analysis of wild-type enzymes and engineered variants · PMID 9726873 · 59 records
• Substrate Specificity of Aqualysin I, a Bacterial Thermophilic Alkaline Serine Protease from Thermus aquaticus YT-1: Comparison with Proteinase K, Subtilisin BPN' and Subtilisin Carlsberg · PMID 27393587 · 38 records
• Substrate specificity of ascorbate oxidase: unexpected similarity to the reduction site of dopamine beta-monooxygenase · PMID 7945293 · 9 records
• Substrate specificity of barley cysteine endoproteases EP-A and EP-B · PMID 9576795 · 45 records
• Substrate specificity of catechol oxidase from Lycopus europaeus and characterization of the bioproducts of enzymic caffeic acid oxidation · PMID 10069382 · 9 records
• Substrate specificity of copper-containing plant amine oxidases · PMID 17521737 · 38 records
• Substrate specificity of cucumisin on synthetic peptides · PMID 11129582 · 12 records
• Substrate specificity of Escherichia coli thymidine phosphorylase · PMID 17309433 · 11 records
• Substrate specificity of flavin-dependent vanillyl-alcohol oxidase from Penicillium simplicissimum. Evidence for the production of 4-hydroxycinnamyl alcohols from 4-allylphenols · PMID 8529652 · 10 records
• Substrate specificity of glutaminyl cyclases from plants and animals · PMID 14719800 · 109 records
• Substrate specificity of glycoside hydrolase family 1 β-glucosidase AtBGlu42 from Arabidopsis thaliana and its molecular mechanism · PMID 34965581 · 32 records
• Substrate specificity of human aldose reductase: identification of 4-hydroxynonenal as an endogenous substrate · PMID 7599164 · 24 records
• Substrate specificity of human cathepsin D using internally quenched fluorescent peptides derived from reactive site loop of kallistatin · PMID 11341921 · 55 records
• Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects · PMID 16321973 · 147 records
• Substrate specificity of human metallocarboxypeptidase D: Comparison of the two active carboxypeptidase domains · PMID 29131831 · 3 records
• Substrate specificity of insect trypsins and the role of their subsites in catalysis · PMID 16431280 · 206 records
• Substrate specificity of king cobra (Ophiophagus hannah) venom L-amino acid oxidase · PMID 2044840 · 42 records
• Substrate specificity of mitochondrial intermediate peptidase analysed by a support-bound peptide library · PMID 26082885 · 15 records
• Substrate specificity of penicillin amidase from E. coli · PMID 7011386 · 14 records
• Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2 · PMID 21291263 · 64 records
• Substrate specificity of RdgB protein, a deoxyribonucleoside triphosphate pyrophosphohydrolase · PMID 17090528 · 12 records
• Substrate specificity of recombinant dengue 2 virus NS2B-NS3 protease: influence of natural and unnatural basic amino acids on hydrolysis of synthetic fluorescent substrates · PMID 17184724 · 51 records
• Substrate specificity of ribose-5-phosphate isomerases from Clostridium difficile and Thermotoga maritima · PMID 20155483 · 8 records
• Substrate specificity of sheep liver sorbitol dehydrogenase · PMID 9461546 · 81 records
• Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C · PMID 21802486 · 9 records
• Substrate specificity of strictosidine synthase · PMID 16481164 · 9 records
• Substrate specificity of the Escherichia coli outer membrane protease OmpP · PMID 17085556 · 20 records
• Substrate specificity of the streptococcal cysteine protease · PMID 11553627 · 35 records
• Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase · PMID 26222439 · 29 records
• Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2) · PMID 20089856 · 10 records
• Substrate specificity, plasma membrane localization, and lipid modification of the aldehyde dehydrogenase ALDH3B1 · PMID 23721920 · 3 records
• Substrate synergism and the kinetic mechanism of yeast hexokinase · PMID 7041974 · 39 records
• Substrate-induced changes in the ammonia channel for imidazole glycerol phosphate synthase · PMID 12795596 · 46 records
• Substrate-Induced Dimerization of Engineered Monomeric Variants of Triosephosphate Isomerase from Trichomonas vaginalis · PMID 26618356 · 10 records
• Substrate-product analogue inhibitors of isoleucine 2-epimerase from Lactobacillus buchneri by rational design · PMID 31528932 · 6 records
• Substrate-specificity of benzyl alcohol dehydrogenase and benzaldehyde dehydrogenase encoded by TOL plasmid pWW0. Metabolic and mechanistic implications · PMID 1590768 · 45 records
• Subunit association as the stabilizing determinant for archaeal methionine adenosyltransferases · PMID 19348969 · 30 records
• Subunit fusion of two yeast D-amino acid oxidases enhances their thermostability and resistance to H2O2 · PMID 18330517 · 8 records
• Succinate thiokinase. VI. Multiple interconvertible forms of the enzyme · PMID 4120859 · 15 records
• Succinic semialdehyde dehydrogenase from the parasitic cattle tick Rhipicephalus microplus: gene identification, biochemical characterization and comparison with the mouse ortholog · PMID 18588919 · 29 records
• SUCCINIC THIOKINASE. II. KINETIC STUDIES: INITIAL VELOCITY, PRODUCT INHIBITION, AND EFFECT OF ARSENATE · PMID 14213385 · 49 records
• Succinyl-CoA:Mesaconate CoA-Transferase and Mesaconyl-CoA Hydratase, Enzymes of the Methylaspartate Cycle in Haloarcula hispanica · PMID 28932214 · 14 records
• Sucrose Isomerase Mutants' Expression in Bacillus subtilis for Isomaltulose Production · PMID 42075214 · 3 records
• Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence · PMID 10592030 · 16 records
• Sugar derivatives as new 6-phosphogluconate dehydrogenase inhibitors selective for the parasite Trypanosoma brucei · PMID 12628648 · 4 records
• Sugar recognition by human galactokinase · PMID 14596685 · 6 records
• Sugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme · PMID 11827479 · 16 records
• Sugar specificity of human beta-cell glucokinase: correlation of molecular models with kinetic measurements · PMID 7742312 · 4 records
• Sugar transport by the bacterial phosphotransferase system. The glucose receptors of the Salmonella typhimurium phosphotransferase system · PMID 6292227 · 10 records
• Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes · PMID 12767217 · 8 records
• Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16 · PMID 20693281 · 3 records
• Sulfoglycolysis sustains Eubacterium rectale in low-fiber diets · PMID 39956340 · 1 record
• Sulphoxidation reaction catalysed by myeloperoxidase from human leucocytes · PMID 9742209 · 22 records
• Suppressive Immune Response of Poly(sarcosine) Conjugated Proteins: PSARylation · PMID 42456079 · 4 records
• Surface charge engineering of PQQ glucose dehydrogenase for downstream processing · PMID 14626410 · 18 records
• Surface engineering of a cutinase from Thermobifida cellulosilytica for improved polyester hydrolysis · PMID 23592055 · 20 records
• Swapping FAD binding motifs between plastidic and bacterial ferredoxin-NADP(H) reductases · PMID 21306142 · 28 records
• Switch of coenzyme specificity of mouse lung carbonyl reductase by substitution of threonine 38 with aspartic acid · PMID 8999926 · 16 records
• Switch of substrate specificity of hyperthermophilic acylaminoacyl peptidase by combination of protein and solvent engineering · PMID 21748600 · 13 records
• Switching kinetic mechanism and putative proton donor by directed mutagenesis of glutathione reductase · PMID 2540822 · 15 records
• Switching the substrate specificity of lysoplasmalogen-specific phospholipase D · PMID 33599379 · 43 records
• Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis · PMID 41556264 · 5 records
• Synthesis and enzymatic ketonization of the 5-(halo)-2-hydroxymuconates and 5-(halo)-2-hydroxy-2,4-pentadienoates · PMID 28684981 · 19 records
• Synthesis and evaluation of xylopyranoside derivatives as "decoy acceptors" of human β-1,4-galactosyltransferase 7 · PMID 21327212 · 12 records
• Synthesis and hydrolysis by cathepsin B of fluorogenic substrates with the general structure benzoyl-X-ARG-MCA containing non-natural basic amino acids at position X · PMID 11343794 · 48 records
• Synthesis of 1-Naphthol by a Natural Peroxygenase Engineered by Directed Evolution · PMID 26677801 · 8 records
• Synthesis of 11-thialinoleic acid and 14-thialinoleic acid, inhibitors of soybean and human lipoxygenases · PMID 18972057 · 8 records
• Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate)… · PMID 19414000 · 14 records
• Synthesis of cinnamyl alcohol from cinnamaldehyde with Bacillus stearothermophilus alcohol dehydrogenase as the isolated enzyme and in recombinant E. coli cells · PMID 23686507 · 5 records
• Synthesis of CMP-9''-modified-sialic acids as donor substrate analogues for mammalian and bacterial sialyltransferases · PMID 17572399 · 20 records
• Synthesis of N3-substituted carboranyl thymidine bioconjugates and their evaluation as substrates of recombinant human thymidine kinase 1 · PMID 23318906 · 10 records
• Synthesis of neuroactive guanidino compounds by rat kidney L-arginine: glycine amidinotransferase · PMID 8035648 · 12 records
• Synthesis of thermostable artificial nicotinamide cofactors: carba-NAD⁺ and carba-NADP · PMID 42164813 · 24 records
• Synthetic peptide substrates for a conductimetric assay of Pseudomonas aeruginosa elastase · PMID 8660569 · 6 records
• Synthetic UDP-galactofuranose analogs reveal critical enzyme-substrate interactions in GlfT2-catalyzed mycobacterial galactan assembly · PMID 22499274 · 7 records
• Systematic exploration of active site mutations on human deoxycytidine kinase substrate specificity · PMID 18361501 · 44 records
• Systematic Functional Analysis of Active-Site Residues in l-Threonine Dehydrogenase from Thermoplasma volcanium · PMID 31457655 · 19 records
• Systematic mutations of highly conserved His49 and carboxyl-terminal of recombinant porcine liver NADH-cytochrome b5 reductase solubilized domain · PMID 10082957 · 27 records
• Systematically Engineering for Efficient Production of 3-Methyl-1-Butanol in Escherichia coli · PMID 41674273 · 2 records
• Systems engineering of tyrosine 195, tyrosine 260, and glutamine 265 in cyclodextrin glycosyltransferase from Paenibacillus macerans to enhance maltodextrin specificity for… · PMID 23160123 · 16 records
• Tailored catalysts for plant cell-wall degradation: redesigning the exo/endo preference of Cellvibrio japonicus arabinanase 43A · PMID 15708971 · 14 records
• Tailoring the specificity of the type C feruloyl esterase FoFaeC from Fusarium oxysporum towards methyl sinapate by rational redesign based on small molecule docking simulations · PMID 29795702 · 24 records
• Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly · PMID 18828589 · 4 records
• Tandem enzymatic oxygenations in biosynthesis of epoxyquinone pharmacophore of manumycin-type metabolites · PMID 23890006 · 9 records
• Tandem-yeast expression system for engineering and producing unspecific peroxygenase · PMID 26002501 · 8 records
• Target RNA-triggered CRISPR-Cas12a2 preferentially cleaves collateral DNA over RNA · PMID 42301915 · 31 records
• Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species · PMID 19624470 · 6 records
• Targeting the active site gate to yield hyperactive variants of 5-aminolevulinate synthase · PMID 20194506 · 20 records
• Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase · PMID 21438567 · 14 records
• Tartronate semialdehyde reductase defines a novel rate-limiting step in assimilation and bioconversion of glycerol in Ustilago maydis · PMID 21305026 · 5 records
• TAS3351 is a brain penetrable EGFR-TKI that overcomes T790M and C797S resistant mutations · PMID 41882274 · 9 records
• Tauropine dehydrogenase from the sandworm Arabella iricolor (Polychaeta: Errantia): purification and characterization · PMID 8840516 · 7 records
• Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the β-lactamase from Mycobacterium tuberculosis · PMID 24846409 · 2 records
• TEM-109 (CMT-5), a natural complex mutant of TEM-1 beta-lactamase combining the amino acid substitutions of TEM-6 and TEM-33 (IRT-5) · PMID 16251281 · 28 records
• TEM-89 beta-lactamase produced by a Proteus mirabilis clinical isolate: new complex mutant (CMT 3) with mutations in both TEM-59 (IRT-17) and TEM-3 · PMID 11709345 · 28 records
• Temperature adaptation of proteins: engineering mesophilic-like activity and stability in a cold-adapted alpha-amylase · PMID 14499602 · 8 records
• Temperature and pH sensitivity of trypsins from Atlantic salmon (Salmo salar) in comparison with bovine and porcine trypsin · PMID 8896331 · 12 records
• Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase · PMID 12199711 · 50 records
• Temperature-dependent modulation of farnesyl diphosphate/geranylgeranyl diphosphate synthase from hyperthermophilic archaea · PMID 15541397 · 12 records
• Tetrameric hotdog-fold structure and catalytic mechanism of the SaPaaI thioesterase from Staphylococcus aureus · PMID 42043294 · 1 record
• Tetrameric structure of the GlfT2 galactofuranosyltransferase reveals a scaffold for the assembly of mycobacterial Arabinogalactan · PMID 22707726 · 8 records
• TetX is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics · PMID 15452119 · 7 records
• The "super mutant" of yeast FMN adenylyltransferase enhances the enzyme turnover rate by attenuating product inhibition · PMID 23663086 · 18 records
• The 'gating' residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition · PMID 21978362 · 13 records
• The 'pH optimum anomaly' of intracellular enzymes of Ferroplasma acidiphilum · PMID 16478448 · 15 records
• THE 21-HYDROXYSTEROID DEHYDROGENASES OF LIVER. A NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE AND TWO NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASES · PMID 14253469 · 18 records
• The 5'-Isobutyryl Ester Prodrug of 4'-Thiouridine Inhibits SARS-CoV‑2 Replication in Culture and in a Syrian Hamster Infection Model · PMID 42540126 · 3 records
• The A26G replacement in the consensus sequence A-X-X-X-X-G-K-[T,S] of the guanine nucleotide binding site activates the intrinsic GTPase of the elongation factor 2 from the archaeon Sulfolobus… · PMID 10336648 · 5 records
• The abnormal accumulation of heparan sulfate in patients with mucopolysaccharidosis prevents the elastolytic activity of cathepsin V · PMID 33278943 · 8 records
• The accessory protein CvnF8 modulates histidine kinase activity in an actinobacterial G protein system in Streptomyces coelicolor · PMID 42200631 · 2 records
• The acid tolerant L-arabinose isomerase from the food grade Lactobacillus sakei 23K is an attractive D-tagatose producer · PMID 20688514 · 6 records
• The activation of rat liver phenylalanine hydroxylase by limited proteolysis, lysolecithin, and tocopherol phosphate. Changes in conformation and catalytic properties · PMID 6501308 · 10 records
• The active site loop of S-adenosylmethionine synthetase modulates catalytic efficiency · PMID 12135357 · 31 records
• The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction · PMID 8313877 · 86 records
• The active sites of fructose 6-phosphate,2-kinase: fructose-2, 6-bisphosphatase from rat testis. Roles of Asp-128, Thr-52, Thr-130, Asn-73, and Tyr-197 · PMID 9065453 · 121 records
• The active-site histidine-10 of enterococcal NADH peroxidase is not essential for catalytic activity · PMID 8652580 · 4 records
• The activity and cofactor preferences of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) change depending on environmental conditions · PMID 21507949 · 6 records
• The aglycone specificity-determining sites are different in 2, 4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA)-glucosidase (Maize beta -glucosidase) and dhurrinase (Sorghum beta -glucosidase) · PMID 10748038 · 27 records
• The AhpC and AhpD antioxidant defense system of Mycobacterium tuberculosis · PMID 10766746 · 14 records
• The Akt C-terminal modulator protein is an acyl-CoA thioesterase of the Hotdog-Fold family · PMID 19453107 · 20 records
• The ALDH21 gene found in lower plants and some vascular plants codes for a NADP⁺ -dependent succinic semialdehyde dehydrogenase · PMID 28749584 · 11 records
• The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase · PMID 33249721 · 5 records
• The allosteric regulation of pyruvate kinase · PMID 10751408 · 15 records
• The alpha-glucuronidase, GlcA67A, of Cellvibrio japonicus utilizes the carboxylate and methyl groups of aldobiouronic acid as important substrate recognition determinants · PMID 12654910 · 10 records
• The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants · PMID 18511072 · 24 records
• The apparent malate synthase activity of Rhodobacter sphaeroides is due to two paralogous enzymes, (3S)-Malyl-coenzyme A (CoA)/β-methylmalyl-CoA lyase and (3S)- Malyl-CoA thioesterase · PMID 20047909 · 7 records
• The Arabidopsis phenylalanine ammonia lyase gene family: kinetic characterization of the four PAL isoforms · PMID 15276452 · 7 records
• The Arabidopsis plastidic methionine sulfoxide reductase B proteins. Sequence and activity characteristics, comparison of the expression with plastidic methionine sulfoxide reductase A, and… · PMID 15923321 · 5 records
• The Arabidopsis thaliana Myo-inositol 1-phosphate synthase1 gene is required for Myo-inositol synthesis and suppression of cell death · PMID 20215587 · 6 records
• The archaeal LDH-like malate dehydrogenase from Ignicoccus islandicus displays dual substrate recognition, hidden allostery and a non-canonical tetrameric oligomeric organization · PMID 31301348 · 2 records
• The ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate base · PMID 24115522 · 8 records
• The AtProT family. Compatible solute transporters with similar substrate specificity but differential expression patterns · PMID 15618414 · 9 records
• The aza-analogues of 1,4-naphthoquinones are potent substrates and inhibitors of plasmodial thioredoxin and glutathione reductases and of human erythrocyte glutathione reductase · PMID 18633531 · 18 records
• The B-ring hydroxylation pattern of anthocyanins can be determined through activity of the flavonoid 3'-hydroxylase on leucoanthocyanidins · PMID 25269395 · 14 records
• The Bacillus subtilis ywkA gene encodes a malic enzyme and its transcription is activated by the YufL/YufM two-component system in response to malate · PMID 12949160 · 2 records
• The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus · PMID 31949045 · 9 records
• The beta-galactosidase (Escherichia coli) reaction is partly facilitated by interactions of His-540 with the C6 hydroxyl of galactose · PMID 8662937 · 44 records
• The bifunctional active site of S-adenosylmethionine synthetase. Roles of the basic residues · PMID 10660564 · 21 records
• The biosynthesis and regulation of biosynthesis of Concord grape fruit esters, including 'foxy' methylanthranilate · PMID 16262710 · 8 records
• The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex · PMID 16055448 · 24 records
• The C-terminal extension of bacterial flavodoxin-reductases: involvement in the hydride transfer mechanism from the coenzyme · PMID 24016470 · 8 records
• The C-terminal lectin-like domain modulates the substrate specificity and transglycosylation activity of rice β-galactosidase1 (OsBGal1) · PMID 41978877 · 5 records
• The C-terminal loop of aldehyde reductase determines the substrate and inhibitor specificity · PMID 8916913 · 15 records
• The C-terminal regulatory domain is required for catalysis by Neisseria meningitidis alpha-isopropylmalate synthase · PMID 20117081 · 10 records
• The carboligation reaction of acetohydroxyacid synthase II: steady-state intermediate distributions in wild type and mutants by NMR · PMID 15640355 · 11 records
• The catabolism of 2,4-xylenol and p-cresol share the enzymes for the oxidation of para-methyl group in Pseudomonas putida NCIMB 9866 · PMID 23736872 · 4 records
• The catalytic activity of pig pepsin C towards small synthetic substrates · PMID 38772 · 12 records
• The catalytic and lectin domains of UDP-GalNAc:polypeptide alpha-N-Acetylgalactosaminyltransferase function in concert to direct glycosylation site selection · PMID 18562306 · 22 records
• The catalytic and other residues essential for the activity of the midgut trehalase from Spodoptera frugiperda · PMID 20691783 · 7 records
• The catalytic architecture of leukotriene C4 synthase with two arginine residues · PMID 21454538 · 46 records
• The catalytic consequences of experimental evolution. Studies on the subunit structure of the second (ebg) beta-galactosidase of Escherichia coli, and on catalysis by ebgab, an experimental evolvant… · PMID 1540130 · 20 records
• The catalytic consequences of experimental evolution. Transition-state structure during catalysis by the evolved beta-galactosidases of Escherichia coli (ebg enzymes) changed by a single mutational… · PMID 2505746 · 31 records
• The catalytic function of the Rev1 dCMP transferase is required in a lesion-specific manner for translesion synthesis and base damage-induced mutagenesis · PMID 20388628 · 6 records
• The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation · PMID 29298880 · 20 records
• The catalytic mechanism of NADH-dependent reduction of 9,10-phenanthrenequinone by Candida tenuis xylose reductase reveals plasticity in an aldo-keto reductase active site · PMID 19368528 · 17 records
• The catalytic mechanism of the hotdog-fold enzyme superfamily 4-hydroxybenzoyl-CoA thioesterase from Arthrobacter sp. strain SU · PMID 22873756 · 25 records
• The catalytic property of 3-hydroxyisobutyrate dehydrogenase from Bacillus cereus on 3-hydroxypropionate · PMID 19517068 · 3 records
• The catalytic role of the distal site asparagine-histidine couple in catalase-peroxidases · PMID 12603334 · 3 records
• The catalytic site of chloroplastic NADP-dependent malate dehydrogenase contains a His/Asp pair · PMID 8665917 · 13 records
• The Characterization of an Efficient Phenylpyruvate Decarboxylase KDC4427, Involved in 2-Phenylethanol and IAA Production from Bacterial Enterobacter sp. CGMCC 5087 · PMID 35377224 · 8 records
• The Characterization of Different Flavodoxin Reductase-Flavodoxin (FNR-Fld) Interactions Reveals an Efficient FNR-Fld Redox Pair and Identifies a Novel FNR Subclass · PMID 30142264 · 7 records
• The characterization of mutant Bacillus subtilis adenylosuccinate lyases corresponding to severe human adenylosuccinate lyase deficiencies · PMID 12876319 · 12 records
• The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography · PMID 15320875 · 36 records
• The cofactor preference of glucose-6-phosphate dehydrogenase from Escherichia coli--modeling the physiological production of reduced cofactors · PMID 22519976 · 12 records
• The combined structural and kinetic characterization of a bacterial nitronate monooxygenase from Pseudomonas aeruginosa PAO1 establishes NMO class I and II · PMID 25002579 · 8 records
• The comparative enzymology of lactic dehydrogenases. 3. Properties of the H4 and M4 enzymes from a number of vertebrates · PMID 6022861 · 20 records
• The comparative interaction of quinonoid (6R)-dihydrobiopterin and an alternative dihydropterin substrate with wild-type and mutant rat dihydropteridine reductases · PMID 9235988 · 24 records
• The complex allosteric and redox regulation of the fumarate hydratase and malate dehydratase reactions of Arabidopsis thaliana Fumarase 1 and 2 gives clues for understanding the massive accumulation… · PMID 29688630 · 23 records
• The conformational switch from the factor X zymogen to protease state mediates exosite expression and prothrombinase assembly · PMID 18460471 · 20 records
• The continued evolution of the L2 cephalosporinase in Stenotrophomonas maltophilia: a key driver of beta-lactam resistance · PMID 39804574 · 9 records
• The contribution of adjacent subunits to the active sites of D-3-phosphoglycerate dehydrogenase · PMID 10026144 · 17 records
• The contribution of lysine-36 to catalysis by human myo-inositol monophosphatase · PMID 8718889 · 16 records
• The coprophilous mushroom Coprinus radians secretes a haloperoxidase that catalyzes aromatic peroxygenation · PMID 17601809 · 6 records
• The crystal structure of an algal prolyl 4-hydroxylase complexed with a proline-rich peptide reveals a novel buried tripeptide binding motif · PMID 19553701 · 19 records
• The crystal structure of an inverting glycoside hydrolase family 9 exo-β-D-glucosaminidase and the design of glycosynthase · PMID 26621872 · 9 records
• The crystal structure of Aquifex aeolicus prephenate dehydrogenase reveals the mode of tyrosine inhibition · PMID 19279014 · 9 records
• The crystal structure of caspase-6, a selective effector of axonal degeneration · PMID 19694615 · 14 records
• The crystal structure of human cytosolic beta-glucosidase unravels the substrate aglycone specificity of a family 1 glycoside hydrolase · PMID 17555766 · 44 records
• The crystal structure of three site-directed mutants of Escherichia coli dihydrodipicolinate synthase: further evidence for a catalytic triad · PMID 15066435 · 8 records
• The Cys(X)5Arg catalytic motif in phosphoester hydrolysis · PMID 7803389 · 12 records
• The Cys319 loop modulates the transition between dehydrogenase and hydrolase conformations in inosine 5'-monophosphate dehydrogenase · PMID 21062060 · 7 records
• The cysteine dioxygenase homologue from Pseudomonas aeruginosa is a 3-mercaptopropionate dioxygenase · PMID 26272617 · 3 records
• The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism · PMID 27588339 · 7 records
• The cytosolic and glycosomal glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma brucei. Kinetic properties and comparison with homologous enzymes · PMID 2040304 · 24 records
• The D-xylose reductase of Hypocrea jecorina is the major aldose reductase in pentose and D-galactose catabolism and necessary for beta-galactosidase and cellulase induction by lactose · PMID 17924946 · 12 records
• The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast · PMID 4291828 · 14 records
• The Dephospho-CoA Kinase of Mycobacterium tuberculosis: Molecular Mechanism and Function · PMID 42825154 · 4 records
• The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase · PMID 9531482 · 7 records
• The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping… · PMID 10419486 · 5 records
• The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity · PMID 28139703 · 4 records
• The Differential Redox Resilience of Alvelestat and Sivelestat: A Mechanistic Hypothesis for Inhibitor Performance Under Oxidative Stress · PMID 42123820 · 2 records
• The DmpA aminopeptidase from Ochrobactrum anthropi LMG7991 is the prototype of a new terminal nucleophile hydrolase family · PMID 10377256 · 9 records
• The Drosophila melanogaster-related angiotensin-I-converting enzymes Acer and Ance--distinct enzymic characteristics and alternative expression during pupal development · PMID 9839949 · 8 records
• The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner · PMID 29187596 · 21 records
• The E2 domain of OdhA of Corynebacterium glutamicum has succinyltransferase activity dependent on lipoyl residues of the acetyltransferase AceF · PMID 20675489 · 8 records
• The effect of a unique halide-stabilizing residue on the catalytic properties of haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 · PMID 23490078 · 6 records
• The effect of C-terminal domain deletion on the catalytic activity of Leishmania donovani surface proteinase GP63: Role of Ser446 in proteolysis · PMID 20678540 · 9 records
• The effect of mutations near the T1 copper site on the biochemical characteristics of the small laccase from Streptomyces coelicolor A3(2) · PMID 25435502 · 8 records
• The Effect of Recombinant Tags on Citrus paradisi Flavonol-Specific 3-O Glucosyltransferase Activity · PMID 32213838 · 6 records
• The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex · PMID 39549 · 20 records
• The effects of multiple ancestral residues on the Thermus thermophilus 3-isopropylmalate dehydrogenase · PMID 16797545 · 18 records
• The Effects of Phosphorylation on the Structure and Function of Motif A, an Intrinsically Disordered Region within SIRT1 · PMID 42610734 · 10 records
• The elusive role of the potential factor X cation-binding exosite-1 in substrate and inhibitor interactions · PMID 14583605 · 53 records
• The enhanced affinity for thiolate anion and activation of enzyme-bound glutathione is governed by an arginine residue of human Mu class glutathione S-transferases · PMID 10652317 · 32 records
• The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis · PMID 11007778 · 2 records
• The enzymatic carboxylation of phosphoenolpyruvate. 3. Investigation of the kinetics and mechanism of the mitochondrial phosphoenolpyruvate carboxykinase-catalyzed reaction · PMID 5911621 · 15 records
• The Enzyme Activity and Substrate Specificity of Two Major Cinnamyl Alcohol Dehydrogenases in Sorghum (Sorghum bicolor), SbCAD2 and SbCAD4 · PMID 28606901 · 27 records
• The enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure · PMID 22750542 · 36 records
• The Escherichia coli Periplasmic Aldehyde Oxidoreductase Is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes · PMID 27622978 · 12 records
• The essential catalytic redox couple in arsenate reductase from Staphylococcus aureus · PMID 10606519 · 6 records
• The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases. Gene cloning, protein expression, and catalytic mechanism · PMID 9603950 · 18 records
• The evolution of substrate discrimination in macrolide antibiotic resistance enzymes · PMID 29317655 · 63 records
• The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity · PMID 31578392 · 30 records
• The external aldimine form of serine palmitoyltransferase: structural, kinetic, and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics · PMID 19376777 · 17 records
• The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines · PMID 23294703 · 2 records
• The facial triad in the α-ketoglutarate dependent oxygenase FIH: A role for sterics in linking substrate binding to O₂ activation · PMID 27815979 · 8 records
• The fast-reacting sulfhydryl group of rat muscle phosphoglycerate kinase is necessary for activity and maintenance of tertiary structure · PMID 7159552 · 9 records
• The feruloyl esterase system of Talaromyces stipitatus: determining the hydrolytic and synthetic specificity of TsFaeC · PMID 16584797 · 17 records
• The first agmatine/cadaverine aminopropyl transferase: biochemical and structural characterization of an enzyme involved in polyamine biosynthesis in the hyperthermophilic archaeon Pyrococcus… · PMID 17545282 · 5 records
• The first archaeal ATP-dependent glucokinase, from the hyperthermophilic crenarchaeon Aeropyrum pernix, represents a monomeric, extremely thermophilic ROK glucokinase with broad hexose specificity · PMID 12374829 · 9 records
• The first mammalian aldehyde oxidase crystal structure: insights into substrate specificity · PMID 23019336 · 25 records
• The flexible motif V of Epstein-Barr virus deoxyuridine 5'-triphosphate pyrophosphatase is essential for catalysis · PMID 19586911 · 15 records
• The fruit ripening-related gene FaAAT2 encodes an acyl transferase involved in strawberry aroma biogenesis · PMID 22563120 · 69 records
• The function of Arg-94 in the oxidation and decarboxylation of glutaryl-CoA by human glutaryl-CoA dehydrogenase · PMID 11024031 · 12 records
• The functional divergence of short-chain dehydrogenases involved in tropinone reduction · PMID 18221363 · 11 records
• The functional role of a conserved loop in EAL domain-based cyclic di-GMP-specific phosphodiesterase · PMID 19376848 · 7 records
• The functional role of cysteines in isopenicillin N synthase. Correlation of cysteine reactivities toward sulfhydryl reagents with kinetic properties of cysteine mutants · PMID 2050677 · 5 records
• The Functional Unit of Neisseria meningitidis 3-Deoxy-ᴅ-Arabino-Heptulosonate 7-Phosphate Synthase Is Dimeric · PMID 26828675 · 4 records
• The functions of key residues in the inhibitor, substrate and cofactor sites of human 3beta-hydroxysteroid dehydrogenase type 1 are validated by mutagenesis · PMID 20420909 · 23 records
• The G473D mutation impairs dimerization and catalysis in human sulfite oxidase · PMID 16475804 · 39 records
• The glucuronidation of Delta4-3-Keto C19- and C21-hydroxysteroids by human liver microsomal and recombinant UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective… · PMID 17151189 · 17 records
• The HD domain of the Escherichia coli tRNA nucleotidyltransferase has 2',3'-cyclic phosphodiesterase, 2'-nucleotidase, and phosphatase activities · PMID 15210699 · 16 records
• The Helicobacter pylori amidotransferase GatCAB is equally efficient in glutamine-dependent transamidation of Asp-tRNAAsn and Glu-tRNAGln · PMID 17329242 · 11 records
• The heterogeneity of mast cell tryptase from human lung and skin · PMID 12605678 · 36 records
• The hexokinase of the hyperthermophile Thermoproteus tenax. ATP-dependent hexokinases and ADP-dependent glucokinases, teo alternatives for glucose phosphorylation in Archaea · PMID 12626506 · 9 records
• The histidine 115-histidine 134 dyad mediates the lactonase activity of mammalian serum paraoxonases · PMID 16407305 · 23 records
• The homotetrameric phosphoseryl-tRNA synthetase from Methanosarcina mazei exhibits half-of-the-sites activity · PMID 18559342 · 8 records
• The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs · PMID 12835412 · 2 records
• The human pyridoxal kinase, a plausible target for ginkgotoxin from Ginkgo biloba · PMID 17250738 · 5 records
• The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation · PMID 23756265 · 13 records
• The human UDP-glucuronosyltransferase: identification of key residues within the nucleotide-sugar binding site · PMID 17578897 · 16 records
• The hyperthermostable indoleglycerol phosphate synthase from Thermotoga maritima is destabilized by mutational disruption of two solvent-exposed salt bridges · PMID 10329177 · 7 records
• The identification and molecular characterization of the first archaeal bifunctional exo-β-glucosidase/N-acetyl-β-glucosaminidase demonstrate that family GH116 is made of three functionally distinct… · PMID 24060745 · 6 records
• The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases · PMID 6935986 · 22 records
• The identity of the active site of oxalate decarboxylase and the importance of the stability of active-site lid conformations · PMID 17680775 · 9 records
• The impact of single nucleotide polymorphisms on human aldehyde oxidase · PMID 22279051 · 95 records
• The influence of conserved aromatic residues in 3-hydroxy-3-methylglutaryl-CoA synthase · PMID 12743118 · 17 records
• The influence of substrate peptide length on human beta-tryptase specificity · PMID 18320560 · 16 records
• The inhibitory effect of halides and carboxylates on hepatic NADH: cytochrome b5 oxidoreductase · PMID 4052043 · 54 records
• The inhibitory effects of lipoic compounds on mammalian pyruvate dehydrogenase complex and its catalytic components · PMID 10218658 · 4 records
• The interaction of the phosphonate analogue of 3-phospho-D-glycerate with phosphoglycerate kinase · PMID 4463959 · 4 records
• The interactions in the carboxyl terminus of human 4-hydroxyphenylpyruvate dioxygenase are critical to mediate the conformation of the final helix and the tail to shield the active site for… · PMID 23950902 · 8 records
• The isolation and characterization of the aspartate transcarbamylase domain of the multifunctional protein, CAD · PMID 6300078 · 2 records
• The isolation and crystallization of yeast and rabbit liver triose phosphate isomerase and a comparative characterization with the rabbit muscle enzyme · PMID 5506172 · 6 records
• The isozymes of glucose-phosphate isomerase (GPI-A2 and GPI-B2) from the teleost fish Fundulus heteroclitus (L.) · PMID 4055792 · 22 records
• The kinase activity of human brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is regulated via inhibition by phosphoenolpyruvate · PMID 15896703 · 51 records
• The kinetic analysis of the substrate specificity of motif 5 in a HAD hydrolase-type phosphosugar phosphatase of Arabidopsis thaliana · PMID 24915748 · 18 records
• The kinetic mechanism of AAC3-IV aminoglycoside acetyltransferase from Escherichia coli · PMID 16331988 · 21 records
• The kinetic properties and sensitivities to inhibitors of lactate dehydrogenases (LDH1 and LDH2) from Toxoplasma gondii: comparisons with pLDH from Plasmodium falciparum · PMID 11704270 · 16 records
• The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment · PMID 23240582 · 8 records
• The kinetic properties of citrate synthase from rat liver mitochondria · PMID 5820645 · 20 records
• The kinetic properties of various R258 mutants of deacetoxycephalosporin C synthase · PMID 12631288 · 28 records
• The kinetic properties producing the perfunctory pH profiles of catalase-peroxidases · PMID 18413236 · 18 records
• The kinetics of pig heart triphosphopyridine nucleotide-isocitrate dehydrogenase. I. Initial velocity, substrate and product inhibition, and isotope exchange studies · PMID 4151308 · 18 records
• The kinetics of rat liver and heart mitochondrial beta-hydroxybutyrate dehydrogenase · PMID 475768 · 24 records
• The kinetics, substrate and inhibitor specificity of the lactate transporter of Ehrlich-Lettre tumour cells studied with the intracellular pH indicator BCECF · PMID 7818477 · 26 records
• The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties - comparative modeling to probe the molecular basis · PMID 17944947 · 6 records
• The last step in cocaine biosynthesis is catalyzed by a BAHD acyltransferase · PMID 25406120 · 8 records
• The LPG1x family from Leishmania major is constituted of rare eukaryotic galactofuranosyltransferases with unprecedented catalytic properties · PMID 30514885 · 11 records
• The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum · PMID 17720817 · 6 records
• The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU · PMID 29684272 · 11 records
• The mechanism of action of the fragile histidine triad, Fhit: isolation of a covalent adenylyl enzyme and chemical rescue of H96G-Fhit · PMID 15182206 · 6 records
• The mechanism of domain alternation in the acyl-adenylate forming ligase superfamily member 4-chlorobenzoate: coenzyme A ligase · PMID 19320426 · 6 records
• The mechanism of kynurenine hydrolysis catalyzed by kynureninase · PMID 118164 · 7 records
• The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenase · PMID 22299628 · 9 records
• The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily · PMID 19678710 · 22 records
• The metabolic role and evolution of L-arabinitol 4-dehydrogenase of Hypocrea jecorina · PMID 15128296 · 13 records
• THE METABOLISM OF GAMMA-HYDROXYGLUTAMATE IN RAT LIVER. I. ENZYMIC SYNTHESIS OF GAMMA-HYDROXY-ALPHA-KETOGLUTARATE FROM PYRUVATE AND GLYOXYLATE · PMID 14089442 · 3 records
• The methylotrophic Bacillus methanolicus MGA3 possesses two distinct fructose 1,6-bisphosphate aldolases · PMID 23760818 · 6 records
• The minimal structure for iodotyrosine deiodinase function is defined by an outlier protein from the thermophilic bacterium Thermotoga neapolitana · PMID 34748729 · 6 records
• The missing link in the fungal D-galacturonate pathway: identification of the L-threo-3-deoxy-hexulosonate aldolase · PMID 17609199 · 5 records
• The molecular basis for acetylhistidine synthesis by HisAT/NAT16 · PMID 40595645 · 12 records
• The molecular basis of the expansive substrate specificity of the antibiotic resistance enzyme aminoglycoside acetyltransferase-6'-aminoglycoside phosphotransferase-2". The role of ASP-99 as an… · PMID 12566434 · 21 records
• The molecular basis of the nonprocessive elongation mechanism in levansucrases · PMID 33303628 · 4 records
• The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua · PMID 18495659 · 5 records
• The molecular mechanism of thermostable α-galactosidases AgaA and AgaB explained by x-ray crystallography and mutational studies · PMID 23012371 · 13 records
• The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase · PMID 10464321 · 3 records
• The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives · PMID 11415433 · 5 records
• The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates · PMID 7961706 · 2 records
• The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages · PMID 18208524 · 5 records
• The Mycobacterium tuberculosis ORF Rv0654 encodes a carotenoid oxygenase mediating central and excentric cleavage of conventional and aromatic carotenoids · PMID 20929460 · 4 records
• The Mycobacterium tuberculosis Rv0132c Gene Product Mtb-FGD2 Can Act as an F₄₂₀-Dependent Glucose Dehydrogenase · PMID 42012189 · 7 records
• The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane · PMID 10497248 · 19 records
• The N-terminal domain of mammalian Lysyl-tRNA synthetase is a functional tRNA-binding domain · PMID 11706011 · 11 records
• The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase · PMID 12574508 · 7 records
• The NAD-dependent glutamate dehydrogenase from Dictyostelium discoideum: purification and properties · PMID 1952936 · 6 records
• The NAD-linked aromatic alpha-hydroxy acid dehydrogenase from Trypanosoma cruzi. A new member of the cytosolic malate dehydrogenases group without malate dehydrogenase activity · PMID 10583384 · 8 records
• The NADH-dependent flavin reductase ThdF follows an ordered sequential mechanism though crystal structures reveal two FAD molecules in the active site · PMID 39725031 · 8 records
• The nature of Staphylococcus aureus MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors · PMID 19298367 · 4 records
• The new beta-D-glucosidase in terpenoid-isoquinoline alkaloid biosynthesis in Psychotria ipecacuanha · PMID 18927081 · 15 records
• The new fluorogenic substrates of neutrophil proteinase 3 optimized in prime site region · PMID 20074540 · 30 records
• The newly discovered Q motif of DEAD-box RNA helicases regulates RNA-binding and helicase activity · PMID 15201868 · 7 records
• The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis · PMID 29703974 · 6 records
• The nitrite reductase from Pseudomonas aeruginosa: essential role of two active-site histidines in the catalytic and structural properties · PMID 11226222 · 6 records
• The nonphosphorylative Entner-Doudoroff pathway in the thermoacidophilic euryarchaeon Picrophilus torridus involves a novel 2-keto-3-deoxygluconate- specific aldolase · PMID 20023024 · 12 records
• The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells · PMID 24467396 · 10 records
• The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine · PMID 10644753 · 8 records
• The Origin and Biosynthesis of the Benzenoid Moiety of Ubiquinone (Coenzyme Q) in Arabidopsis · PMID 24838974 · 5 records
• The origin of the high sensitivity of muscle fructose 1,6-bisphosphatase towards AMP · PMID 16213487 · 8 records
• The oxidation of adrenaline and noradrenaline by the two forms of monoamine oxidase from human and rat brain · PMID 20493079 · 22 records
• The oxidation of hydrazine derivatives catalyzed by the purified liver microsomal FAD-containing monooxygenase · PMID 7217078 · 18 records
• The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein · PMID 10373420 · 6 records
• The oxyanion hole of Pseudomonas fluorescens mannitol 2-dehydrogenase: a novel structural motif for electrostatic stabilization in alcohol dehydrogenase active sites · PMID 19857201 · 16 records
• The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion · PMID 18845175 · 29 records
• The pentose phosphate pathway of cellulolytic clostridia relies on 6-phosphofructokinase instead of transaldolase · PMID 31871051 · 7 records
• The peroxisomal Acyl-CoA thioesterase Pte1p from Saccharomyces cerevisiae is required for efficient degradation of short straight chain and branched chain fatty acids · PMID 16490786 · 6 records
• The pH Requirement for in Vivo Activity of the Iron-Deficiency-Induced "Turbo" Ferric Chelate Reductase (A Comparison of the Iron-Deficiency-Induced Iron Reductase Activities of Intact Plants and… · PMID 12226175 · 22 records
• The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme · PMID 29995887 · 8 records
• The phosphonopyruvate decarboxylase from Bacteroides fragilis · PMID 12904299 · 6 records
• The plant cysteine oxidases from Arabidopsis thaliana are kinetically tailored to act as oxygen sensors · PMID 29848548 · 10 records
• The processing of human mitochondrial leucyl-tRNA synthetase in the insect cells · PMID 12527375 · 6 records
• The prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenase · PMID 14610090 · 7 records
• The Production and Utilization of GDP-glucose in the Biosynthesis of Trehalose 6-Phosphate by Streptomyces venezuelae · PMID 27903647 · 14 records
• The Progesterone 5β-Reductase/Iridoid Synthase Family: A Catalytic Reservoir for Specialized Metabolism across Land Plants · PMID 32501002 · 22 records
• The properties and potential metabolic role of glucokinase in halotolerant obligate methanotroph Methylomicrobium alcaliphilum 20Z · PMID 27915410 · 4 records
• The proton transfer step catalyzed by yeast pyruvate kinase · PMID 12562754 · 16 records
• The purification and properties of cyclohexanone oxygenase from Nocardia globerula CL1 and Acinetobacter NCIB 9871 · PMID 1261545 · 18 records
• The purification, characterization, cloning and sequencing of the gene for a halostable and thermostable leucine dehydrogenase from Thermoactinomyces intermedius · PMID 8020469 · 13 records
• The putative catalytic bases have, at most, an accessory role in the mechanism of arginine kinase · PMID 12732621 · 14 records
• The putative malate/lactate dehydrogenase from Pseudomonas putida is an NADPH-dependent delta1-piperideine-2-carboxylate/delta1-pyrroline-2-carboxylate reductase involved in the catabolism of… · PMID 15561717 · 8 records
• The pyridoxal 5'-phosphate (PLP)-dependent enzyme serine palmitoyltransferase (SPT): effects of the small subunits and insights from bacterial mimics of human hLCB2a HSAN1 mutations · PMID 24175284 · 6 records
• The pyruvate decarboxylase activity of IpdC is a limitation for isobutanol production by Klebsiella pneumoniae · PMID 35501883 · 18 records
• The quaternary structure of Escherichia coli N-acetylneuraminate lyase is essential for functional expression · PMID 19646958 · 11 records
• The quest for a thermostable sucrose phosphorylase reveals sucrose 6'-phosphate phosphorylase as a novel specificity · PMID 24599311 · 6 records
• The quinohemoprotein alcohol dehydrogenase of Gluconobacter suboxydans has ubiquinol oxidation activity at a site different from the ubiquinone reduction site · PMID 9878716 · 40 records
• The quorum-quenching lactonase from Alicyclobacter acidoterrestris: purification, kinetic characterization, crystallization and crystallographic analysis · PMID 28777091 · 4 records
• The R117A variant of the Escherichia coli transacylase FabD synthesizes novel acyl-(acyl carrier proteins) · PMID 29075826 · 10 records
• The RadA protein from a hyperthermophilic archaeon Pyrobaculum islandicum is a DNA-dependent ATPase that exhibits two disparate catalytic modes, with a transition temperature at 75 degrees C · PMID 10672022 · 18 records
• The regulation by fibrinogen and fibrin of tissue plasminogen activator kinetics and inhibition by plasminogen activator inhibitor 1 · PMID 17408411 · 12 records
• THE RELATIONSHIPS BETWEEN SUBSTRATES AND ENZYMES OF GLYCOLYSIS IN BRAIN · PMID 14114860 · 23 records
• The release of N-acetyl- and N-glycolloyl-neuraminic acid from soluble complex carbohydrates and erythrocytes by bacterial, viral and mammalian sialidases · PMID 7325957 · 36 records
• The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon · PMID 18668122 · 8 records
• The role in the substrate specificity and catalysis of residues forming the substrate aglycone-binding site of a beta-glycosidase · PMID 18422657 · 35 records
• The role of a beta barrel loop 4 extension in modulating the physical and functional properties of long-chain 2-hydroxy-acid oxidase isozymes · PMID 8706682 · 16 records
• The role of a conserved histidine residue in a pyruvate-specific Class II aldolase · PMID 18775708 · 3 records
• The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276 · PMID 19351161 · 12 records
• The Role of Active Site Residues in ATP Binding and Catalysis in the Methanosarcina thermophila Acetate Kinase · PMID 25775277 · 30 records
• The role of active site tyrosine 58 in Citrobacter freundii methionine γ-lyase · PMID 25584856 · 10 records
• The role of ala198 in the stability and coenzyme specificity of bacterial formate dehydrogenases · PMID 25927002 · 11 records
• The role of amino acid residues in the active site of L-methionine γ-lyase from Pseudomonas putida · PMID 22785484 · 31 records
• The role of aristolochene synthase in diphosphate activation · PMID 22349314 · 7 records
• The role of Asp-295 in the catalytic mechanism of Leuconostoc mesenteroides sucrose phosphorylase probed with site-directed mutagenesis · PMID 17350620 · 16 records
• The role of cations in avian liver phosphoenolpyruvate carboxykinase catalysis. Activation and regulation · PMID 6796577 · 5 records
• The role of cysteine 160 in thiamine diphosphate binding of the Calvin-Benson-Bassham cycle transketolase of Rhodobacter sphaeroides · PMID 15130781 · 14 records
• The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase · PMID 19019081 · 12 records
• The role of factor XIa (FXIa) catalytic domain exosite residues in substrate catalysis and inhibition by the Kunitz protease inhibitor domain of protease nexin 2 · PMID 21778227 · 16 records
• The role of Gln269Leu mutation on the thermostability and structure of uricase from Aspergillus flavus · PMID 40064946 · 2 records
• The role of Glu498 in the dioxygen reactivity of CotA-laccase from Bacillus subtilis · PMID 20200715 · 12 records
• The role of glutamate 87 in the kinetic mechanism of Thermus thermophilus isopropylmalate dehydrogenase · PMID 8535253 · 26 records
• The role of glycine residues 140 and 141 of subunit B in the functional ubiquinone binding site of the Na+-pumping NADH:quinone oxidoreductase from Vibrio cholerae · PMID 22645140 · 4 records
• The role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphatase · PMID 18647345 · 19 records
• The role of histidines in the acetate kinase from Methanosarcina thermophila · PMID 10958794 · 28 records
• The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase · PMID 11985586 · 34 records
• The role of kinase domain dimerization in EGFR activation · PMID 41421344 · 9 records
• The role of lysine residues 297 and 306 in nucleoside triphosphate regulation of E. coli CTP synthase: inactivation by 2',3'-dialdehyde ATP and mutational analyses · PMID 16427816 · 15 records
• The role of lysine-234 in beta-lactamase catalysis probed by site-directed mutagenesis · PMID 1974463 · 48 records
• The Role of Metal Complexation in the Unfolding Energetics of a Nudix Hydrolase · PMID 41995431 · 6 records
• The role of N286 and D320 in the reaction mechanism of human dihydrolipoamide dehydrogenase (E3) center domain · PMID 17171578 · 16 records
• The role of OXA-1 beta-lactamase Asp(66) in the stabilization of the active-site carbamate group and in substrate turnover · PMID 18031291 · 31 records
• The role of phosphagen specificity loops in arginine kinase · PMID 14978299 · 24 records
• The role of residue Thr249 in modulating the catalytic efficiency and substrate specificity of catechol-2,3-dioxygenase from Pseudomonas stutzeri OX1 · PMID 16734718 · 16 records
• The role of the Aedes aegypti Epsilon glutathione transferases in conferring resistance to DDT and pyrethroid insecticides · PMID 21195177 · 18 records
• The role of the allosteric B site in the fumarase reaction · PMID 14990798 · 10 records
• The role of the conserved residues His-246, His-199, and Tyr-255 in the catalysis of catechol 2,3-dioxygenase from Pseudomonas stutzeri OX1 · PMID 15347689 · 15 records
• The role of the lys628 (192) residue of the complement protease, c1s, in interacting with Peptide and protein substrates · PMID 25278939 · 9 records
• The role of the S1 binding site of carboxypeptidase M in substrate specificity and turn-over · PMID 17208058 · 68 records
• The role of Tyr605 and Ala607 of thimet oligopeptidase and Tyr606 and Gly608 of neurolysin in substrate hydrolysis and inhibitor binding · PMID 17313369 · 82 records
• The role of tyrosine 343 in substrate binding and catalysis by human sulfite oxidase · PMID 14729666 · 44 records
• The roles of active site residues in the catalytic mechanism of methylaspartate ammonia-lyase · PMID 23905011 · 8 records
• The roles of conserved carboxylate residues in IMP dehydrogenase and identification of a transition state analog · PMID 9341229 · 24 records
• The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major · PMID 9153248 · 29 records
• The roles of Ser-36, Asp-132 and Asp-201 in the reaction of Pseudomonas fluorescens Kynureninase · PMID 31100408 · 2 records
• The second conserved motif in bacterial laccase regulates catalysis and robustness · PMID 29516145 · 16 records
• The second-shell metal ligands of human arginase affect coordination of the nucleophile and substrate · PMID 21053939 · 14 records
• The seven human coronavirus main proteases exhibit differential modulation of NF-κB suppression via TAB1 cleavage · PMID 42168570 · 14 records
• The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5' to 3' viral helicases · PMID 12917423 · 8 records
• The site for GTP hydrolysis on the archaeal elongation factor 2 is unmasked by aliphatic alcohols · PMID 9116052 · 11 records
• The small subunit of snapdragon geranyl diphosphate synthase modifies the chain length specificity of tobacco geranylgeranyl diphosphate synthase in planta · PMID 20028839 · 18 records
• The specificity of alcohol dehydrogenase with cis-retinoids. Activity with 11-cis-retinol and localization in retina · PMID 15096205 · 47 records
• The stacking tryptophan of galactose oxidase: a second-coordination sphere residue that has profound effects on tyrosyl radical behavior and enzyme catalysis · PMID 17385891 · 6 records
• The stereoselectivity and catalytic properties of Xanthobacter autotrophicus 2-[(R)-2-Hydroxypropylthio]ethanesulfonate dehydrogenase are controlled by interactions between C-terminal arginine… · PMID 15157110 · 26 records
• The stratagem utilized by the plasminogen activator from the snake Trimeresurus stejnegeri to escape serpins · PMID 12081498 · 14 records
• The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation · PMID 12899635 · 7 records
• The streptococcal hyaluronan synthases are inhibited by sulfhydryl-modifying reagents, but conserved cysteine residues are not essential for enzyme function · PMID 11799120 · 38 records
• The structural and functional basis of catalysis mediated by NAD(P)H:acceptor Oxidoreductase (FerB) of Paracoccus denitrificans · PMID 24817153 · 21 records
• The structural and mutational analyses of O-ureido-L-serine synthase necessary for D-cycloserine biosynthesis · PMID 26207937 · 20 records
• The structural basis for catalysis and specificity of the Pseudomonas cellulosa alpha-glucuronidase, GlcA67A · PMID 11937059 · 5 records
• The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase · PMID 15044458 · 5 records
• The structural basis of substrate promiscuity in glucose dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus · PMID 16556607 · 14 records
• The structural basis of substrate promiscuity in UDP-hexose 4-epimerase from the hyperthermophilic Eubacterium Thermotoga maritima · PMID 26344854 · 4 records
• The structural basis of substrate selectivity of the acinetobactin biosynthetic adenylation domain, BasE · PMID 40096888 · 33 records
• The Structural Determinants Accounting for the Broad Substrate Specificity of the Quorum Quenching Lactonase GcL · PMID 30864300 · 13 records
• The structural mechanism for the nucleoside tri- and diphosphate hydrolysis activity of Ntdp from Staphylococcus aureus · PMID 33955674 · 18 records
• The structural roles of a conserved small hydrophobic core in the active site and an ionic bridge in domain I of Delta class glutathione S-transferase · PMID 16153184 · 26 records
• The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a--an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity · PMID 26783088 · 5 records
• The structure of a putative S-formylglutathione hydrolase from Agrobacterium tumefaciens · PMID 19653299 · 6 records
• The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism · PMID 15769597 · 24 records
• The Structure of Murine N¹-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism · PMID 28029774 · 10 records
• The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance · PMID 31883412 · 12 records
• The structure of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei reveals a zinc binding site at the heart of the active site · PMID 20447408 · 3 records
• The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coli · PMID 17652087 · 12 records
• The substrate specificity of cruzipain 2, a cysteine protease isoform from Trypanosoma cruzi · PMID 16734782 · 23 records
• The Substrate Versatility of Δ¹-Pyrroline-5-carboxylate Reductase (ProC) from Escherichia coli · PMID 41683478 · 9 records
• The suicide inactivation of ox liver short-chain acyl-CoA dehydrogenase by propionyl-CoA. Formation of an FAD adduct · PMID 4062874 · 1 record
• The sulfuryl transfer mechanism. Crystal structure of a vanadate complex of estrogen sulfotransferase and mutational analysis · PMID 9765259 · 19 records
• The T296V Mutant of Amorpha-4,11-diene Synthase Is Defective in Allylic Diphosphate Isomerization but Retains the Ability To Cyclize the Intermediate (3R)-Nerolidyl Diphosphate to Amorpha-4,11-diene · PMID 27933789 · 5 records
• The tandemly repeated domains of a β-propeller phytase act synergistically to increase catalytic efficiency · PMID 21707924 · 7 records
• The temperature dependence of activity and structure for the most prevalent mutant aldolase B associated with hereditary fructose intolerance · PMID 12464284 · 28 records
• The terminal adenosine of tRNA(Gln) mediates tRNA-dependent amino acid recognition by glutaminyl-tRNA synthetase · PMID 9657697 · 19 records
• The thermophilic archaeon Sulfolobus solfataricus is able to grow on phenol · PMID 15921893 · 6 records
• The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes · PMID 28341845 · 48 records
• The tRNA-dependent activation of arginine by arginyl-tRNA synthetase requires inter-domain communication · PMID 10993737 · 64 records
• The tRNA-interacting factor p43 associates with mammalian arginyl-tRNA synthetase but does not modify its tRNA aminoacylation properties · PMID 15078106 · 4 records
• The tryptophan synthase β-subunit paralogs TrpB1 and TrpB2 in Thermococcus kodakarensis are both involved in tryptophan biosynthesis and indole salvage · PMID 24835339 · 6 records
• The two analogous phosphoglycerate mutases of Escherichia coli · PMID 10437801 · 4 records
• The two homologous domains of human angiotensin I-converting enzyme are both catalytically active · PMID 1851160 · 12 records
• The unique functional role of the C-HS hydrogen bond in the substrate specificity and enzyme catalysis of type 1 methionine aminopeptidase · PMID 27225936 · 4 records
• The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase · PMID 19588076 · 11 records
• The unraveling of substrate specificity of histone deacetylase 6 domains using acetylome peptide microarrays and peptide libraries · PMID 30496698 · 32 records
• The ureide-degrading reactions of purine ring catabolism employ three amidohydrolases and one aminohydrolase in Arabidopsis, soybean, and rice · PMID 23940254 · 10 records
• The urinary tract commensal Peptoniphilus spp. encodes a novel 17β-hydroxysteroid dehydrogenase · PMID 42657876 · 2 records
• The use of fluoro- and deoxy-substrate analogs to examine binding specificity and catalysis in the enzymes of the sorbitol pathway · PMID 10209867 · 33 records
• The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase · PMID 10630424 · 7 records
• The versatile O-methyltransferase LrOMT catalyzes multiple O-methylation reactions in amaryllidaceae alkaloids biosynthesis · PMID 31494163 · 8 records
• The vertebrate alcohol dehydrogenase system: variable class II type form elucidates separate stages of enzymogenesis · PMID 7479907 · 4 records
• The X-ray crystal structures of human alpha-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a · PMID 16540464 · 4 records
• The xylan-degrading enzyme system of Talaromyces emersonii: novel enzymes with activity against aryl beta-D-xylosides and unsubstituted xylans · PMID 8452541 · 10 records
• The ywad gene from Bacillus subtilis encodes a double-zinc aminopeptidase · PMID 15668014 · 11 records
• The ZN domain acts as a dynamic switch coordinating multiple-step aminoacylation in bacterial leucyl-tRNA synthetase · PMID 42573068 · 15 records
• The zymogenic form of SARS-CoV-2 main protease: A discrete target for drug discovery · PMID 39675720 · 2 records
• The β and γ subunits play distinct functional roles in the α₂βγ heterotetramer of human NAD-dependent isocitrate dehydrogenase · PMID 28139779 · 19 records
• The β2αB loop determines NAD(P) cofactor specificity and kinetics in trypanosomal D-3-hydroxybutyrate dehydrogenases · PMID 42456964 · 46 records
• Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers · PMID 17401542 · 8 records
• Thermal stabilization of the deglycating enzyme Amadoriase I by rational design · PMID 29445091 · 5 records
• Thermal unfolding studies of cold adapted uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua). A comparative study with human UNG · PMID 21959147 · 12 records
• Thermoanaerobacterium thermosulfurigenes cyclodextrin glycosyltransferase · PMID 12492486 · 12 records
• Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA · PMID 30586940 · 8 records
• Thermodynamic analysis shows conformational coupling and dynamics confer substrate specificity in fructose-1,6-bisphosphate aldolase · PMID 17935305 · 15 records
• Thermodynamic and kinetic analysis of the isolated FAD domain of rat neuronal nitric oxide synthase altered in the region of the FAD shielding residue Phe1395 · PMID 15182370 · 8 records
• Thermodynamic insights into the structural basis governing the donor substrate recognition by human beta1,4-galactosyltransferase 7 · PMID 19032152 · 9 records
• Thermolysin: kinetic study with oligopeptides · PMID 4993757 · 40 records
• Thermostable alcohol dehydrogenase from Thermococcus kodakarensis KOD1 for enantioselective bioconversion of aromatic secondary alcohols · PMID 23354700 · 9 records
• Thermostable aminopeptidase from Pyrococcus horikoshii · PMID 10218575 · 11 records
• Thermostable beta-galactosidase from the archaebacterium Sulfolobus solfataricus. Purification and properties · PMID 2105216 · 4 records
• Thermostable esterase from a thermoacidophilic archaeon: purification and characterization for enzymatic resolution of a chiral compound · PMID 15564667 · 5 records
• Thermostable variants of pyranose 2-oxidase showing altered substrate selectivity for glucose and galactose · PMID 20158200 · 6 records
• Thermotoga maritima MazG protein has both nucleoside triphosphate pyrophosphohydrolase and pyrophosphatase activities · PMID 12657645 · 8 records
• Thermotoga maritima TM0298 is a highly thermostable mannitol dehydrogenase · PMID 18719905 · 9 records
• Thermotolerant D-Hydantoinases for Efficient and Stereoselective Intermediate Synthesis of (R)-3-Isobutylglutaric Acid Monoamide, a Key Intermediate in Pregabalin Production · PMID 41846534 · 6 records
• Thiamin Diphosphate Activation in 1-Deoxy-d-xylulose 5-Phosphate Synthase: Insights into the Mechanism and Underlying Intermolecular Interactions · PMID 27537621 · 10 records
• Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): a homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs · PMID 19405909 · 30 records
• Thiol S-methyltransferase from rat liver · PMID 485170 · 18 records
• Thiolation-enhanced substrate recognition by D-alanyl carrier protein ligase DltA from Bacillus cereus · PMID 25285205 · 9 records
• Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus · PMID 18313035 · 5 records
• Thioredoxin Reductase-Type Ferredoxin: NADP⁺ Oxidoreductase of Rhodopseudomonas palustris: Potentiometric Characteristics and Reactions with Nonphysiological Oxidants · PMID 35624864 · 35 records
• Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum: structural and functional insights into thiosulfate oxidation · PMID 25673691 · 12 records
• Thr373, Asp375, and Lys260 are in the coenzyme site of porcine NADP-dependent isocitrate dehydrogenase · PMID 16712772 · 11 records
• Three bovine alpha2-fucosyltransferase genes encode enzymes that preferentially transfer fucose on Galbeta1-3GalNAc acceptor substrates · PMID 10814703 · 6 records
• Three different classes of aminotransferases evolved prephenate aminotransferase functionality in arogenate-competent microorganisms · PMID 24302739 · 17 records
• Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors · PMID 8218285 · 16 records
• Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties · PMID 10455188 · 18 records
• Three new O-methyltransferases are sufficient for all O-methylation reactions of ipecac alkaloid biosynthesis in root culture of Psychotria ipecacuanha · PMID 20061395 · 11 records
• Three prime repair exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural, and conformational properties · PMID 38838778 · 8 records
• Three-dimensional structure and catalytic mechanism of cytosine deaminase · PMID 21545144 · 9 records
• Three-dimensional structure of phosphoenolpyruvate carboxylase: a proposed mechanism for allosteric inhibition · PMID 9927652 · 6 records
• Three-step hydroxylation of vitamin D3 by a genetically engineered CYP105A1: enzymes and catalysis · PMID 20731719 · 3 records
• Threonine 201 in the diiron enzyme toluene 4-monooxygenase is not required for catalysis · PMID 10651645 · 4 records
• Threonine 246 at the active site of the L-lactate dehydrogenase of Bacillus stearothermophilus is important for catalysis but not for substrate binding · PMID 8251493 · 35 records
• Threonine-insensitive homoserine dehydrogenase from soybean: genomic organization, kinetic mechanism, and in vivo activity · PMID 19897476 · 30 records
• Thymidine kinase 1 regulatory fine-tuning through tetramer formation · PMID 23351158 · 20 records
• Thymidylate kinase of Mycobacterium tuberculosis: a chimera sharing properties common to eukaryotic and bacterial enzymes · PMID 11369858 · 9 records
• Tissue factor alters the pK(a) values of catalytically important factor VIIa residues · PMID 11876644 · 20 records
• TK1211 Encodes an Amino Acid Racemase towards Leucine and Methionine in the Hyperthermophilic Archaeon Thermococcus kodakarensis · PMID 33468590 · 4 records
• TK2268 encodes the major aminotransferase involved in the conversion from oxaloacetic acid to aspartic acid in Thermococcus kodakarensis · PMID 39992121 · 4 records
• Tonotopic specialization of MYO7A isoforms in auditory hair cells · PMID 42236700 · 2 records
• Toward tailoring the specificity of the S1 pocket of subtilisin B. lentus: chemical modification of mutant enzymes as a strategy for removing specificity limitations · PMID 10529215 · 21 records
• Toward Understanding the Catalytic Mechanism of Human Paraoxonase 1: Site-Specific Mutagenesis at Position 192 · PMID 26829396 · 5 records
• Toxicity of Bordetella avium beta-cystathionase toward MC3T3-E1 osteogenic cells · PMID 8463265 · 2 records
• Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog · PMID 16829527 · 4 records
• Transcellular proteolysis demonstrated by novel cell surface-associated substrates of dipeptidyl peptidase IV (CD26) · PMID 12095981 · 9 records
• Transcription analysis of pyranose dehydrogenase from the basidiomycete Agaricus bisporus and characterization of the recombinantly expressed enzyme · PMID 26616098 · 13 records
• Transcriptional and Biochemical Characterization of Cytosolic Pyruvate Kinases in Arabidopsis thaliana · PMID 32168758 · 10 records
• Transcriptome-wide identification and characterization of CAD isoforms specific for podophyllotoxin biosynthesis from Podophyllum hexandrum · PMID 27387305 · 8 records
• Transgalactosylation by thermostable beta-glycosidases from Pyrococcus furiosus and Sulfolobus solfataricus. Binding interactions of nucleophiles with the galactosylated enzyme intermediate make… · PMID 10931188 · 8 records
• Transgenic down-regulation of caffeic acid O-methyltransferase (COMT) led to improved digestibility in tall fescue (Festuca arundinacea) · PMID 32688895 · 6 records
• Transglycosylation Activity of Engineered Bifidobacterium Lacto-N-Biosidase Mutants at Donor Subsites for Lacto-N-Tetraose Synthesis · PMID 33810098 · 14 records
• Transient and equilibrium kinetic studies on yeast 3-phosphoglycerate kinase. Evidence that an intermediate containing 1,3-bisphosphoglycerate accumulates in the steady state · PMID 7827041 · 8 records
• Transient-State Analysis of Porcine Dihydropyrimidine Dehydrogenase Reveals Reductive Activation by NADPH · PMID 32516529 · 12 records
• Transition state analogues rescue ribosomes from saporin-L1 ribosome inactivating protein · PMID 19764816 · 4 records
• Transition State Analysis of the Reaction Catalyzed by the Phosphotriesterase from Sphingobium sp. TCM1 · PMID 30730705 · 27 records
• Transition state stabilization by six arginines clustered in the active site of creatine kinase · PMID 16005271 · 14 records
• Transition-State Analogues of Campylobacter jejuni 5'-Methylthioadenosine Nucleosidase · PMID 30339406 · 5 records
• Transition-state analysis of the arginine-specific human ADP-ribosyltransferase 1 · PMID 42201951 · 10 records
• Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis · PMID 16630632 · 7 records
• Transketolase A of Escherichia coli K12. Purification and properties of the enzyme from recombinant strains · PMID 7607225 · 13 records
• Transmitting the allosteric signal in methylglyoxal synthase · PMID 23592737 · 20 records
• Trapping choline oxidase in a nonfunctional conformation by freezing at low pH · PMID 17143885 · 4 records
• Treponema denticola cystalysin exhibits significant alanine racemase activity accompanied by transamination: mechanistic implications · PMID 12519070 · 5 records
• Trimethylation of histone H3 lysine 36 by human methyltransferase PRDM9 protein · PMID 24634223 · 16 records
• Triphosphopyridine nucleotide-linked aldehyde reductase. I. Purification and properties of the enzyme from pig kidney cortex · PMID 4402936 · 13 records
• Triple serine loop region regulates the aspartate racemase activity of the serine/aspartate racemase family · PMID 28744579 · 64 records
• tRNA recognition by a bacterial tRNA Xm32 modification enzyme from the SPOUT methyltransferase superfamily · PMID 26202969 · 15 records
• Tropine forming tropinone reductase gene from Withania somnifera (Ashwagandha): biochemical characteristics of the recombinant enzyme and novel physiological overtones of tissue-wide gene expression… · PMID 24086372 · 24 records
• Trp-999 of beta-galactosidase (Escherichia coli) is a key residue for binding, catalysis, and synthesis of allolactose, the natural lac operon inducer · PMID 12578395 · 10 records
• TrpB2 enzymes are O-phospho-l-serine dependent tryptophan synthases · PMID 25184516 · 4 records
• Trypanosoma brucei thymidine kinase is tandem protein consisting of two homologous parts, which together enable efficient substrate binding · PMID 22442154 · 14 records
• Trypanosome mRNA recapping is triggered by hypermethylation originating from cap 4 · PMID 39011881 · 16 records
• Trypanothione synthesis in crithidia revisited · PMID 15537651 · 6 records
• Trypsin cleavage of human cystathionine beta-synthase into an evolutionarily conserved active core: structural and functional consequences · PMID 9675031 · 10 records
• Tryptophan prenyltransferases showing higher catalytic activities for Friedel-Crafts alkylation of o- and m-tyrosines than tyrosine prenyltransferases · PMID 26077893 · 6 records
• Tryptophan-47 in the active site of Methylophaga sp. strain SK1 flavin-monooxygenase is important for hydride transfer · PMID 23357278 · 10 records
• Tryptophanase from Proteus vulgaris: the conformational rearrangement in the active site, induced by the mutation of Tyrosine 72 to phenylalanine, and its mechanistic consequences · PMID 16455316 · 8 records
• Tryptophanase Mining and Characterization toward the Biological Production of Indole Derivatives · PMID 41835499 · 18 records
• Two (betaalpha)(8)-barrel enzymes of histidine and tryptophan biosynthesis have similar reaction mechanisms and common strategies for protecting their labile substrates · PMID 12356303 · 11 records
• Two active forms of UDP-N-acetylglucosamine enolpyruvyl transferase in gram-positive bacteria · PMID 10894720 · 4 records
• Two active site arginines are critical determinants of substrate binding and catalysis in MenD: a thiamine-dependent enzyme in menaquinone biosynthesis · PMID 30341164 · 10 records
• Two aldehyde dehydrogenases from human liver. Isolation via affinity chromatography and characterization of the isozymes · PMID 18196 · 14 records
• Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis · PMID 20061481 · 15 records
• Two alternative substrate paths for compound I formation and reduction in catalase-peroxidase KatG from Burkholderia pseudomallei · PMID 17063492 · 27 records
• Two bifunctional enzymes from the marine protist Thraustochytrium roseum: biochemical characterization of wax ester synthase/acyl-CoA:diacylglycerol acyltransferase activity catalyzing wax… · PMID 28725265 · 18 records
• Two cinnamoyl-CoA reductase (CCR) genes from Arabidopsis thaliana are differentially expressed during development and in response to infection with pathogenic bacteria · PMID 11430991 · 6 records
• Two conserved histidine residues are critical to the function of the TagF-like family of enzymes · PMID 16141206 · 6 records
• Two D-2-hydroxy-acid dehydrogenases in Arabidopsis thaliana with catalytic capacities to participate in the last reactions of the methylglyoxal and beta-oxidation pathways · PMID 19586914 · 11 records
• Two different dihydroorotate dehydrogenases from yeast Saccharomyces kluyveri · PMID 15196933 · 10 records
• Two distinct alcohol dehydrogenase classes mediate bacterial 2-hydroxyethylphosphonate catabolism · PMID 42742056 · 5 records
• Two distinct arabinofuranosidases contribute to arabino-oligosaccharide degradation in Bacillus subtilis · PMID 18757805 · 10 records
• Two distinct cinnamoyl-CoA reductases in Selaginella moellendorffii offer insight into the divergence of CCRs in plants · PMID 28321576 · 12 records
• Two distinct domains of the beta subunit of Aquifex aeolicus leucyl-tRNA synthetase are involved in tRNA binding as revealed by a three-hybrid selection · PMID 15208367 · 26 records
• Two essential regions for tRNA recognition in Bacillus subtilis tryptophanyl-tRNA synthetase · PMID 11966471 · 7 records
• Two esterases released from Mycobacterium smegmatis from the hydrolysis of long chain acyl-CoAs and Tween · PMID 7334001 · 6 records
• Two forms of NADP-dependent malic enzyme in expanding maize leaves · PMID 24407260 · 32 records
• Two Fusarium copper radical oxidases with high activity on aryl alcohols · PMID 34134727 · 27 records
• Two genes in Arabidopsis thaliana encoding GDP-L-galactose phosphorylase are required for ascorbate biosynthesis and seedling viability · PMID 17877701 · 8 records
• Two ginseng UDP-glycosyltransferases synthesize ginsenoside Rg3 and Rd · PMID 25320211 · 4 records
• Two Glu/Asp residues cooperatively mediate an early step of ATP hydrolysis in GHKL ATPases MutL and GyrB · PMID 42788712 · 13 records
• Two glucosyltransferases are involved in detoxification of benzoxazinoids in maize · PMID 11851909 · 6 records
• Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase · PMID 11781092 · 16 records
• Two glyceraldehyde-3-phosphate dehydrogenases with opposite physiological roles in a nonphotosynthetic bacterium · PMID 10799476 · 6 records
• Two L-amino acid oxidase isoenzymes from Russell's viper (Daboia russelli russelli) venom with different mechanisms of inhibition by substrate analogs · PMID 18384385 · 12 records
• Two methionine aminopeptidases from Acinetobacter baumannii are functional enzymes · PMID 21524572 · 8 records
• Two NADH-dependent (S)-3-hydroxyacyl-CoA dehydrogenases from polyhydroxyalkanoate-producing Ralstonia eutropha · PMID 30243533 · 6 records
• Two New Unspecific Peroxygenases from Heterologous Expression of Fungal Genes in Escherichia coli · PMID 31980430 · 16 records
• Two novel cyclodextrin-degrading enzymes isolated from thermophilic bacteria have similar domain structures but differ in oligomeric state and activity profile · PMID 16310726 · 10 records
• Two Novel Glycoside Hydrolases Responsible for the Catabolism of Cyclobis-(1→6)-α-nigerosyl · PMID 27302067 · 5 records
• Two novel metal-independent long-chain alkyl alcohol dehydrogenases from Geobacillus thermodenitrificans NG80-2 · PMID 19383697 · 12 records
• Two novel mutant human adenylosuccinate lyases (ASLs) associated with autism and characterization of the equivalent mutant Bacillus subtilis ASL · PMID 15471876 · 12 records
• Two oxidation sites for low redox potential substrates: a directed mutagenesis, kinetic, and crystallographic study on Pleurotus eryngii versatile peroxidase · PMID 23071108 · 99 records
• Two radical-dependent mechanisms for anaerobic degradation of the globally abundant organosulfur compound dihydroxypropanesulfonate · PMID 32571930 · 3 records
• Two shikimate dehydrogenases, VvSDH3 and VvSDH4, are involved in gallic acid biosynthesis in grapevine · PMID 27241494 · 12 records
• Two thymidine kinases and one multisubstrate deoxyribonucleoside kinase salvage DNA precursors in Arabidopsis thaliana · PMID 22897443 · 15 records
• Two trehalose-hydrolyzing enzymes from Crenarchaeon Sulfolobus acidocaldarius exhibit distinct activities and affinities toward trehalose · PMID 29574614 · 6 records
• Two Tropinone Reductases with Distinct Stereospecificities from Cultured Roots of Hyoscyamus niger · PMID 16653065 · 21 records
• Two tyrosine residues outside the editing active site in Giardia lamblia leucyl-tRNA synthetase are essential for the post-transfer editing · PMID 19540202 · 10 records
• Two tyrosine residues, Tyr-108 and Tyr-503, are responsible for the deprotonation of phenolic substrates in vanillyl-alcohol oxidase · PMID 28717004 · 6 records
• Two UGT84 Family Glycosyltransferases Catalyze a Critical Reaction of Hydrolyzable Tannin Biosynthesis in Pomegranate (Punica granatum) · PMID 27227328 · 16 records
• Two-step bioconversion of pyridoxal 5'-phosphate from pyridoxine through cofactor regeneration and pyridoxine 5'-phosphate oxidase evolution · PMID 42006857 · 4 records
• Type I Arginine Methyltransferases PRMT1 and PRMT-3 Act Distributively · PMID 19158082 · 10 records
• Tyr219 of human matrix metalloproteinase 7 is not critical for catalytic activity, but is involved in the broad pH-dependence of the activity · PMID 21593056 · 14 records
• Tyr235 of human cytosolic phosphoenolpyruvate carboxykinase influences catalysis through an anion-quadrupole interaction with phosphoenolpyruvate carboxylate · PMID 19021757 · 38 records
• Tyrosinase-Mediated Oxidation of Endocannabinoid and Endovanilloid N-Arachidonoyl Dopamine and N-Arachidonoyl Tyrosine · PMID 42509833 · 4 records
• Tyrosine 105 and threonine 212 at outermost substrate binding subsites -6 and +4 control substrate specificity, oligosaccharide cleavage patterns, and multiple binding modes of barley alpha-amylase… · PMID 14660599 · 17 records
• Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations · PMID 21153519 · 7 records
• Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1β aspartate aminotransferase · PMID 30771275 · 10 records
• Tyrosine Residues 232 and 401 Play a Critical Role in the Binding of the Cofactor FAD of Acyl-coA Oxidase · PMID 29372418 · 5 records
• Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry · PMID 41879255 · 6 records
• Tyrosine residues near the FAD binding site are critical for FAD binding and for the maintenance of the stable and active conformation of rat monoamine oxidase A · PMID 11754741 · 21 records
• Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H… · PMID 8117659 · 19 records
• Tyrosine83 is essential for the activity of E. coli galactoside transacetylase · PMID 17208523 · 12 records
• Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors · PMID 29402945 · 23 records
• UDP-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (Bellis perennis) flowers. Enzymology and phylogenetics of a novel glucuronosyltransferase involved in flower pigment… · PMID 15509561 · 6 records
• UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues · PMID 31836608 · 20 records
• UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree · PMID 22186971 · 17 records
• UDP-sugar pyrophosphorylase with broad substrate specificity toward various monosaccharide 1-phosphates from pea sprouts · PMID 15326166 · 8 records
• Ultrahigh and high resolution structures and mutational analysis of monomeric Streptococcus pyogenes SpeB reveal a functional role for the glycine-rich C-terminal loop · PMID 22645124 · 10 records
• UMP kinase from Streptococcus pneumoniae: evidence for co-operative ATP binding and allosteric regulation · PMID 15324307 · 4 records
• Uncovering divergent evolution of α/β-hydrolases: a surprising residue substitution needed to convert Hevea brasiliensis hydroxynitrile lyase into an esterase · PMID 25346843 · 20 records
• Understanding functional divergence in proteins by studying intragenomic homologues · PMID 18281960 · 26 records
• Understanding in vivo benzenoid metabolism in petunia petal tissue · PMID 15286288 · 6 records
• Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed… · PMID 20369883 · 8 records
• Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus · PMID 24649856 · 8 records
• Understanding the Catalytic Determinant role of Diaphorase-Like Subunit in Formate Dehydrogenases via Redox Couples · PMID 42154453 · 5 records
• Understanding the Molecular Mechanism Underlying the High Catalytic Activity of p-Hydroxybenzoate Hydroxylase Mutants for Producing Gallic Acid · PMID 31639299 · 3 records
• Understanding the role of residues around the active site tunnel towards generating a glucose-tolerant β-glucosidase from Agrobacterium tumefaciens 5A · PMID 28873987 · 38 records
• Unidirectional mannitol synthesis of Acinetobacter baumannii MtlD is facilitated by the helix-loop-helix-mediated dimer formation · PMID 35363566 · 19 records
• Unique coenzyme binding mode of hyperthermophilic archaeal sn-glycerol-1-phosphate dehydrogenase from Pyrobaculum calidifontis · PMID 27616573 · 8 records
• Unique substrate recognition mechanism of the botulinum neurotoxin D light chain · PMID 23963459 · 17 records
• Unique substrate specificity of ornithine aminotransferase from Toxoplasma gondii · PMID 28126740 · 15 records
• Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration · PMID 42206565 · 1 record
• Unlocking Lignin's Potential: Engineered Bacterial Laccases to Produce Biologically Active Molecules · PMID 39258808 · 33 records
• Unraveling Additional O-Methylation Steps in Benzylisoquinoline Alkaloid Biosynthesis in California Poppy (Eschscholzia californica) · PMID 28922749 · 10 records
• Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α₂β₂ Acyl-CoA Dehydrogenase Initiates β-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA · PMID 26161441 · 6 records
• Unraveling multistate unfolding of pig kidney fructose-1,6-bisphosphatase using single tryptophan mutants · PMID 17894826 · 6 records
• Unraveling the difference between invertases and fructan exohydrolases: a single amino acid (Asp-239) substitution transforms Arabidopsis cell wall invertase1 into a fructan 1-exohydrolase · PMID 17873089 · 13 records
• Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus · PMID 23296511 · 18 records
• Unraveling the kinetic diversity of microbial 3-dehydroquinate dehydratases of shikimate pathway · PMID 25852984 · 34 records
• Unraveling the mechanisms of tryptophan fluorescence quenching in the triosephosphate isomerase from Giardia lamblia · PMID 18620084 · 9 records
• Unravelling Regioselectivity of Leuconostoc citreum ABK-1 Alternansucrase by Acceptor Site Engineering · PMID 33810084 · 10 records
• Unusual extra space at the active site and high activity for acetylated hydroxyproline of prolyl aminopeptidase from Serratia marcescens · PMID 16452443 · 15 records
• Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes · PMID 10833458 · 9 records
• Unusual substrate specificity of the peptidoglycan MurE ligase from Erysipelothrix rhusiopathiae · PMID 26700151 · 8 records
• Unveiling 14 novel 2-hydroxy acid racemization and epimerization reactions in the lactate racemase superfamily · PMID 39667499 · 96 records
• Unveiling a catalytically promiscuous feruloyl esterase from Clostridium acetobutylicum · PMID 41781769 · 2 records
• Unveiling the mechanism of dye-decolorizing peroxidase (DyP): unique anthraquinone-directed catalysis exposes a dual-function peroxidase · PMID 42017670 · 15 records
• Unveiling the Transgalactosylation Switch of a GH42 β‑Galactosidase from the Infant Isolate Bifidobacterium breve DSM20213 · PMID 41676231 · 2 records
• Update on biochemical properties of recombinant Pseudomonas diminuta phosphotriesterase · PMID 19548794 · 5 records
• UPF0586 Protein C9orf41 Homolog Is Anserine-producing Methyltransferase · PMID 26001783 · 8 records
• Uridine diphosphate N-acetylglucosamine homeostasis via CgNgk1 kinase modulates chitin levels and cell-wall integrity in Candida glabrata · PMID 41769087 · 6 records
• Use of an Isotope-Coded Mass Tag (ICMT) Method To Determine the Orientation of Cholesterol Oxidase on Model Membranes · PMID 30125103 · 18 records
• Use of docking peptides to design modular substrates with high efficiency for mitogen-activated protein kinase extracellular signal-regulated kinase · PMID 17918909 · 12 records
• Use of endoproteases to identify catalytic domains, linker regions, and functional interactions in soluble peptidylglycine alpha-amidating monooxygenase · PMID 8486658 · 9 records
• Use of indirect site-directed mutagenesis to alter the substrate specificity of methylamine dehydrogenase · PMID 11733518 · 23 records
• Use of site-directed mutagenesis to identify residues specific for each reaction catalyzed by chorismate mutase-prephenate dehydrogenase from Escherichia coli · PMID 9843375 · 31 records
• Use of structural comparisons to select mutagenic targets in aspartate-beta-semialdehyde dehydrogenase · PMID 7756269 · 20 records
• Using a bioluminescence resonance energy transfer caspase biosensor to study caspase-3 cleavage site specificity · PMID 41816988 · 45 records
• Using a molecular model and kinetic experiments in the presence of divalent cations to study the active site and catalysis of Pseudomonas aeruginosa phosphorylcholine phosphatase · PMID 18801468 · 14 records
• Using substrate analogues to probe the kinetic mechanism and active site of Escherichia coli MenD · PMID 21928762 · 45 records
• Utilisation of 10-formyldihydrofolate as substrate by dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) tranformylase/IMP cyclohydrolase (PurH) in… · PMID 29799386 · 7 records
• Utilization of multiple substrates by butyrate kinase from Listeria monocytogenes · PMID 27940001 · 18 records
• UTP-bound and Apo structures of a minimal RNA uridylyltransferase · PMID 17189640 · 18 records
• Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6 · PMID 12485962 · 11 records
• Valine dehydrogenase from Streptomyces fradiae: purification and properties · PMID 3269392 · 17 records
• Variable sulfation of dietary polyphenols by recombinant human sulfotransferase (SULT) 1A1 genetic variants and SULT1E1 · PMID 17293380 · 14 records
• Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase · PMID 16027371 · 1 record
• Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation · PMID 19569192 · 5 records
• Variants of Phosphotriesterase for the Enhanced Detoxification of the Chemical Warfare Agent VR · PMID 26274608 · 122 records
• Variation in the divalent cation requirements of influenza A virus N1 neuraminidases · PMID 16567409 · 12 records
• Vein Patterning 1-encoded progesterone 5β-reductase: activity-guided improvement of catalytic efficiency · PMID 22357344 · 12 records
• Versatile Fungal Polyphenol Oxidase with Chlorophenol Bioremediation Potential: Characterization and Protein Engineering · PMID 30266731 · 7 records
• Versatile peroxidase of Bjerkandera fumosa: substrate and inhibitor specificity · PMID 23199738 · 28 records
• Versatile peroxidase oxidation of high redox potential aromatic compounds: site-directed mutagenesis, spectroscopic and crystallographic investigation of three long-range electron transfer pathways · PMID 16246366 · 12 records
• Versatility of putative aromatic aminotransferases from Candida albicans · PMID 29199101 · 15 records
• Vgb from Staphylococcus aureus inactivates streptogramin B antibiotics by an elimination mechanism not hydrolysis · PMID 11467949 · 7 records
• Virtual screening of mandelate racemase mutants with enhanced activity based on binding energy in the transition state · PMID 24411454 · 17 records
• Virus-encoded aminoacyl-tRNA synthetases: structural and functional characterization of mimivirus TyrRS and MetRS · PMID 17855524 · 14 records
• Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase · PMID 18823127 · 11 records
• Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS? · PMID 22745722 · 5 records
• Wildtype and engineered monomeric triosephosphate isomerase from Trypanosoma brucei: partitioning of reaction intermediates in D2O and activation by phosphite dianion · PMID 21553855 · 13 records
• WOR5, a novel tungsten-containing aldehyde oxidoreductase from Pyrococcus furiosus with a broad substrate Specificity · PMID 16199576 · 14 records
• WrbA from Escherichia coli and Archaeoglobus fulgidus is an NAD(P)H:quinone oxidoreductase · PMID 16672604 · 6 records
• X-ray crystallographic analysis of the 6-aminohexanoate cyclic dimer hydrolase: catalytic mechanism and evolution of an enzyme responsible for nylon-6 byproduct degradation · PMID 19889645 · 6 records
• X-ray crystallographic and site-directed mutagenesis analysis of the mechanism of Schiff-base formation in phosphonoacetaldehyde hydrolase catalysis · PMID 14670958 · 8 records
• X-ray structure and characterization of carbamate kinase from the human parasite Giardia lamblia · PMID 20383005 · 4 records
• X-Ray Structure and Mutagenesis Studies of the N-Isopropylammelide Isopropylaminohydrolase, AtzC · PMID 26390431 · 14 records
• Xanthine oxidase from human liver: purification and characterization · PMID 3010873 · 35 records
• Xanthosine and xanthine. Substrate properties with purine nucleoside phosphorylases, and relevance to other enzyme systems · PMID 12180982 · 24 records
• Xenopus laevis CYP17 regulates androgen biosynthesis independent of the cofactor cytochrome b5 · PMID 15640159 · 27 records
• Xylo- and cello-oligosaccharide oxidation by gluco-oligosaccharide oxidase from Sarocladium strictum and variants with reduced substrate inhibition · PMID 24119501 · 73 records
• Xylose reductase from the Basidiomycete fungus Cryptococcus flavus: purification, steady-state kinetic characterization, and detailed analysis of the substrate binding pocket using… · PMID 12761304 · 41 records
• Xylose reductase from the thermophilic fungus Talaromyces emersonii: cloning and heterologous expression of the native gene (Texr) and a double mutant (TexrK271R + N273D) with altered coenzyme… · PMID 20093741 · 8 records
• Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine · PMID 18291415 · 8 records
• Yeast epiarginase regulation, an enzyme-enzyme activity control: identification of residues of ornithine carbamoyltransferase and arginase responsible for enzyme catalytic and regulatory activities · PMID 12679340 · 27 records
• Yeast glyoxalase I is a monomeric enzyme with two active sites · PMID 11050082 · 7 records
• Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment · PMID 22343532 · 40 records
• Yeast sterol C24-methyltransferase: role of highly conserved tyrosine-81 in catalytic competence studied by site-directed mutagenesis and thermodynamic analysis · PMID 18555004 · 14 records
• Yellow fever virus NS2B/NS3 protease: hydrolytic properties and substrate specificity · PMID 21419753 · 21 records
• Yerba mate (Ilex paraguariensis) genome provides new insights into convergent evolution of caffeine biosynthesis · PMID 39773819 · 3 records
• YhbO is a DJ-1 family glyoxalase and α-oxoaldehyde hydratase that confers resistance to reactive carbonyl stress · PMID 42372922 · 5 records
• YqfB protein from Escherichia coli: an atypical amidohydrolase active towards N⁴-acylcytosine derivatives · PMID 31964920 · 20 records
• Zinc-mediated allosteric inhibition of caspase-6 · PMID 22891250 · 5 records
• Zinc-mediated amino acid discrimination in cysteinyl-tRNA synthetase · PMID 12662918 · 13 records
• ²H kinetic isotope effects and pH dependence of catalysis as mechanistic probes of rat monoamine oxidase A: comparisons with the human enzyme · PMID 21819071 · 28 records
• α-N-acetylgalactosaminidase from infant-associated bifidobacteria belonging to novel glycoside hydrolase family 129 is implicated in alternative mucin degradation pathway · PMID 22090027 · 7 records
• β-Cyanoalanine Synthases and Their Possible Role in Pierid Host Plant Adaptation · PMID 28629163 · 26 records
• μ₃-Oxo nucleophile formation enables efficient S_N2 hydrolysis at the trinuclear metal center in inorganic pyrophosphatase · PMID 41927744 · 3 records
• ω-Hydroxyacid Dehydrogenases From Clostridium viride: Iron-Containing Biocatalysts With Biotechnological Potential · PMID 42626997 · 23 records