CatLogenzyme kinetics catalog

Values CatLog read from this paper

Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core

PMID 30457329doi:10.1021/acs.biochem.8b00497Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 9 records (16 values) from this paper: UDP-glucose dehydrogenase (hUGDH) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 7 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 1.1.1.22

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
UDP-glucose dehydrogenase (hUGDH)Homo sapiensNAD+0.94——pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)Homo sapiensUDP-glucoseUDP-Glc saturation curve with NAD+ fixed at 5 mM (Table 3)0.590.007678 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)Homo sapiensUDP-glucoseUDP-Glc saturation curves at 00.590.007480 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)Homo sapiensUDP-glucoseUDP-Glc saturation curve in the presence of 2.7 μM UDP-Xyl0.45——pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)variant A104GHomo sapiensUDP-glucose0.670.017239 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)variant A104LHomo sapiensNAD+0.790.04816 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)variant A104LHomo sapiensUDP-glucoseUDP-Glc saturation curve with NAD+ fixed at 5 mM (Table 3)0.820.009487 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)variant A104LHomo sapiensUDP-glucoseUDP-Glc saturation curves at 00.840.010382 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)variant A104LHomo sapiensUDP-glucose0.850.008897 calc.pH 7.5, 25 °COpen