Values CatLog read from this paper
Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation
PMID 19569192doi:10.1002/pro.171Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 5 records (15 values) from this paper: thymidylate synthase from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| thymidylate synthase | Homo sapiens | 2'-deoxyuridine 5'-monophosphate | 3.11 | 0.00259 | 1.2 × 10³ | 37 °C | Open record: thymidylate synthase, 2'-deoxyuridine 5'-monophosphate |
| thymidylate synthasevariant A191K | Homo sapiens | 2'-deoxyuridine 5'-monophosphate | 0.52 | 8.5 × 10⁻⁴ | 610 | 37 °C | Open record: thymidylate synthase variant A191K, 2'-deoxyuridine 5'-monophosphate |
| thymidylate synthasevariant L198P | Homo sapiens | 2'-deoxyuridine 5'-monophosphate | 1.64 | 0.01563 | 100 | 37 °C | Open record: thymidylate synthase variant L198P, 2'-deoxyuridine 5'-monophosphate |
| thymidylate synthasevariant M190E | Homo sapiens | 2'-deoxyuridine 5'-monophosphate | 0.53 | 9.6 × 10⁻⁴ | 550 | 37 °C | Open record: thymidylate synthase variant M190E, 2'-deoxyuridine 5'-monophosphate |
| thymidylate synthasevariant M190K | Homo sapiens | 2'-deoxyuridine 5'-monophosphate | 0.03 | 0.179 | 0.16 | 37 °C | Open record: thymidylate synthase variant M190K, 2'-deoxyuridine 5'-monophosphate |