Values CatLog read from this paper
Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates
PMID 22123821doi:10.1074/jbc.m111.313015Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 14 records (26 values) from this paper: UDP-glucose 6-dehydrogenase (hUGDH) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| UDP-glucose 6-dehydrogenase (hUGDH) | Homo sapiens | NAD+pH profile (pH 5.0-10.5); ionic strength 0.1 M | — | — | 2.715 | 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH), NAD+ |
| UDP-glucose 6-dehydrogenase (hUGDH) | Homo sapiens | NAD+initial rates from NADH absorbance at 340 nm | 1.1 | — | — | 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH), NAD+ |
| UDP-glucose 6-dehydrogenase (hUGDH) | Homo sapiens | UDP-alpha-D-glucose | 1.1 | — | — | 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH), UDP-alpha-D-glucose |
| UDP-glucose 6-dehydrogenase (hUGDH)variant D280A | Homo sapiens | NAD+ | — | — | 2 × 10⁻⁶ | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant D280A, NAD+ |
| UDP-glucose 6-dehydrogenase (hUGDH)variant D280A | Homo sapiens | UDP-alpha-D-glucose | — | 0.07 | — | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant D280A, UDP-alpha-D-glucose |
| UDP-glucose 6-dehydrogenase (hUGDH)variant E161Q | Homo sapiens | NAD+ | — | 0.1 | 0.014 | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant E161Q, NAD+ |
| UDP-glucose 6-dehydrogenase (hUGDH)variant E161Q | Homo sapiens | UDP-alpha-D-glucose | 0.0014 | 0.055 | 0.025 | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant E161Q, UDP-alpha-D-glucose |
| UDP-glucose 6-dehydrogenase (hUGDH)variant K220A | Homo sapiens | NAD+ | — | 0.15 | 1.3 × 10⁻⁵ | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant K220A, NAD+ |
| UDP-glucose 6-dehydrogenase (hUGDH)variant K220A | Homo sapiens | UDP-alpha-D-glucose | 2 × 10⁻⁶ | 0.04 | 5 × 10⁻⁵ | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant K220A, UDP-alpha-D-glucose |
| UDP-glucose 6-dehydrogenase (hUGDH)variant K220A | Homo sapiens | UDP-alpha-D-glucoseapparent kcat | 2.3 × 10⁻⁴ | — | — | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant K220A, UDP-alpha-D-glucose |
| UDP-glucose 6-dehydrogenase (hUGDH)variant N224A | Homo sapiens | NAD+ | — | 2.9 | 0.1 | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant N224A, NAD+ |
| UDP-glucose 6-dehydrogenase (hUGDH)variant N224A | Homo sapiens | UDP-alpha-D-glucose | 0.3 | 0.18 | 1.7 | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant N224A, UDP-alpha-D-glucose |
| UDP-glucose 6-dehydrogenase (hUGDH)variant T131S | Homo sapiens | NAD+ | — | 0.7 | 0.6 | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant T131S, NAD+ |
| UDP-glucose 6-dehydrogenase (hUGDH)variant T131S | Homo sapiens | UDP-alpha-D-glucose | 0.45 | 0.04 | 11.3 | pH 7.5, 25 °C | Open record: UDP-glucose 6-dehydrogenase (hUGDH) variant T131S, UDP-alpha-D-glucose |