Values CatLog read from this paper

Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant

PMID 27486859doi:10.1111/febs.13828Open in Browse

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CatLog read 6 records (14 values) from this paper: dimethylglycine dehydrogenase (hDMGDH) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.5.8.4

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
dimethylglycine dehydrogenase (hDMGDH)Homo sapiensN,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP0.730.32.43pH 7.8, 25 °COpen record: dimethylglycine dehydrogenase (hDMGDH), N,N-dimethylglycine
dimethylglycine dehydrogenase (hDMGDH)Homo sapiensN,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP; approximate Km—30—pH 7.8, 25 °COpen record: dimethylglycine dehydrogenase (hDMGDH), N,N-dimethylglycine
dimethylglycine dehydrogenase (hDMGDH)Homo sapiensN,N-dimethylglycineferrocenium assay: 50 mM HEPES/NaOH; 0.1 mM EDTA3.551.42.28pH 7.8, 25 °COpen record: dimethylglycine dehydrogenase (hDMGDH), N,N-dimethylglycine
dimethylglycine dehydrogenase (hDMGDH)variant H109RHomo sapiensN,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP1.524.70.33pH 7.8, 25 °COpen record: dimethylglycine dehydrogenase (hDMGDH) variant H109R, N,N-dimethylglycine
dimethylglycine dehydrogenase (hDMGDH)variant H109RHomo sapiensN,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP; approximate Km—90—pH 7.8, 25 °COpen record: dimethylglycine dehydrogenase (hDMGDH) variant H109R, N,N-dimethylglycine
dimethylglycine dehydrogenase (hDMGDH)variant H109RHomo sapiensN,N-dimethylglycineferrocenium assay: 50 mM HEPES/NaOH; 0.1 mM EDTA9.0732.20.18pH 7.8, 25 °COpen record: dimethylglycine dehydrogenase (hDMGDH) variant H109R, N,N-dimethylglycine