Values CatLog read from this paper
Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant
PMID 27486859doi:10.1111/febs.13828Open in Browse
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CatLog read 6 records (14 values) from this paper: dimethylglycine dehydrogenase (hDMGDH) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| dimethylglycine dehydrogenase (hDMGDH) | Homo sapiens | N,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP | 0.73 | 0.3 | 2.43 | pH 7.8, 25 °C | Open record: dimethylglycine dehydrogenase (hDMGDH), N,N-dimethylglycine |
| dimethylglycine dehydrogenase (hDMGDH) | Homo sapiens | N,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP; approximate Km | — | 30 | — | pH 7.8, 25 °C | Open record: dimethylglycine dehydrogenase (hDMGDH), N,N-dimethylglycine |
| dimethylglycine dehydrogenase (hDMGDH) | Homo sapiens | N,N-dimethylglycineferrocenium assay: 50 mM HEPES/NaOH; 0.1 mM EDTA | 3.55 | 1.4 | 2.28 | pH 7.8, 25 °C | Open record: dimethylglycine dehydrogenase (hDMGDH), N,N-dimethylglycine |
| dimethylglycine dehydrogenase (hDMGDH)variant H109R | Homo sapiens | N,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP | 1.52 | 4.7 | 0.33 | pH 7.8, 25 °C | Open record: dimethylglycine dehydrogenase (hDMGDH) variant H109R, N,N-dimethylglycine |
| dimethylglycine dehydrogenase (hDMGDH)variant H109R | Homo sapiens | N,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP; approximate Km | — | 90 | — | pH 7.8, 25 °C | Open record: dimethylglycine dehydrogenase (hDMGDH) variant H109R, N,N-dimethylglycine |
| dimethylglycine dehydrogenase (hDMGDH)variant H109R | Homo sapiens | N,N-dimethylglycineferrocenium assay: 50 mM HEPES/NaOH; 0.1 mM EDTA | 9.07 | 32.2 | 0.18 | pH 7.8, 25 °C | Open record: dimethylglycine dehydrogenase (hDMGDH) variant H109R, N,N-dimethylglycine |