CatLogenzyme kinetics catalog

EC 1.5.8.4: dimethylglycine dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 6 records for EC 1.5.8.4 from 1 paper, for 1 organism. Names in these papers: dimethylglycine dehydrogenase (hDMGDH).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 5 records for EC 1.5.8.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.5.8.4 in Browse.

Papers

PaperOrganismsRecords
Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variantHomo sapiens6

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
dimethylglycine dehydrogenase (hDMGDH)Homo sapiensN,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP0.730.32.43pH 7.8, 25 °CPMID 27486859Open
dimethylglycine dehydrogenase (hDMGDH)Homo sapiensN,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP; approximate Km—30—pH 7.8, 25 °CPMID 27486859Open
dimethylglycine dehydrogenase (hDMGDH)Homo sapiensN,N-dimethylglycineferrocenium assay: 50 mM HEPES/NaOH; 0.1 mM EDTA3.551.42.28pH 7.8, 25 °CPMID 27486859Open
dimethylglycine dehydrogenase (hDMGDH)variant H109RHomo sapiensN,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP1.524.70.33pH 7.8, 25 °CPMID 27486859Open
dimethylglycine dehydrogenase (hDMGDH)variant H109RHomo sapiensN,N-dimethylglycineDCPIP assay: 50 mM HEPES/NaOH; 135 µM DCPIP; approximate Km—90—pH 7.8, 25 °CPMID 27486859Open
dimethylglycine dehydrogenase (hDMGDH)variant H109RHomo sapiensN,N-dimethylglycineferrocenium assay: 50 mM HEPES/NaOH; 0.1 mM EDTA9.0732.20.18pH 7.8, 25 °CPMID 27486859Open