Values CatLog read from this paper
Role of Ambler Position 104 in Defining Substrate Specificity in the KPC Family of β-Lactamases
PMID 42047351doi:10.1021/acsinfecdis.6c00071Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 5 records (15 values) from this paper: KPC-3 from Klebsiella pneumoniae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| KPC-3 | Klebsiella pneumoniae | ceftazidime | 79 | 3.504 | 20 | pH 7.4 | Open record: KPC-3, ceftazidime |
| KPC-3variant P104K | Klebsiella pneumoniae | cefiderocol | 13.5 | 0.866 | 16 | pH 7.4 | Open record: KPC-3 variant P104K, cefiderocol |
| KPC-3variant P104K | Klebsiella pneumoniae | ceftazidime | 95 | 0.34 | 270 | pH 7.4 | Open record: KPC-3 variant P104K, ceftazidime |
| KPC-3variant P104R | Klebsiella pneumoniae | cefiderocol | 8.4 | 0.424 | 19 | pH 7.4 | Open record: KPC-3 variant P104R, cefiderocol |
| KPC-3variant P104R | Klebsiella pneumoniae | ceftazidime | 92 | 0.595 | 160 | pH 7.4 | Open record: KPC-3 variant P104R, ceftazidime |