Values CatLog read from this paper
Ile209 of Leishmania donovani xanthine phosphoribosyltransferase plays a key role in determining its purine base specificity
PMID 34268726doi:10.1002/1873-3468.14162Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 20 records (60 values) from this paper: xanthine phosphoribosyltransferase (LdXPRT) from Leishmania donovani.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| xanthine phosphoribosyltransferase (LdXPRT) | Leishmania donovani | 5-phospho-alpha-D-ribose 1-diphosphate1.0 mM xanthine; cosubstrate xanthine | 2 | 0.01885 | 106 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT), 5-phospho-alpha-D-ribose 1-diphosphate |
| xanthine phosphoribosyltransferase (LdXPRT) | Leishmania donovani | 5-phospho-alpha-D-ribose 1-diphosphate1.0 mM hypoxanthine; cosubstrate hypoxanthine | 1.3 | 0.04176 | 31.1 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT), 5-phospho-alpha-D-ribose 1-diphosphate |
| xanthine phosphoribosyltransferase (LdXPRT) | Leishmania donovani | guanine | 0.455 | 0.1037 | 4.3 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT), guanine |
| xanthine phosphoribosyltransferase (LdXPRT) | Leishmania donovani | hypoxanthine | 1.1 | 0.2042 | 5.3 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT), hypoxanthine |
| xanthine phosphoribosyltransferase (LdXPRT) | Leishmania donovani | xanthine | 1.8 | 0.0089 | 202.2 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT), xanthine |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V | Leishmania donovani | 5-phospho-alpha-D-ribose 1-diphosphate1.0 mM xanthine; cosubstrate xanthine | 4.38 | 0.0299 | 146 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, 5-phospho-alpha-D-ribose 1-diphosphate |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V | Leishmania donovani | 5-phospho-alpha-D-ribose 1-diphosphate1.0 mM hypoxanthine; cosubstrate hypoxanthine | 1.21 | 0.03576 | 33.8 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, 5-phospho-alpha-D-ribose 1-diphosphate |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V | Leishmania donovani | guanine | 0.518 | 0.0373 | 13.8 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, guanine |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V | Leishmania donovani | hypoxanthine | 1.23 | 0.04862 | 25.2 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, hypoxanthine |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V | Leishmania donovani | xanthine | 4.19 | 0.06662 | 62.8 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, xanthine |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D | Leishmania donovani | 5-phospho-alpha-D-ribose 1-diphosphate1.0 mM xanthine; cosubstrate xanthine | 13.29 | 0.03669 | 362.2 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, 5-phospho-alpha-D-ribose 1-diphosphate |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D | Leishmania donovani | 5-phospho-alpha-D-ribose 1-diphosphate1.0 mM hypoxanthine; cosubstrate hypoxanthine | 7.99 | 0.02257 | 354 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, 5-phospho-alpha-D-ribose 1-diphosphate |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D | Leishmania donovani | guanine | 8.68 | 0.01441 | 602.3 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, guanine |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D | Leishmania donovani | hypoxanthine | 9.89 | 0.02649 | 373.3 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, hypoxanthine |
| xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D | Leishmania donovani | xanthine | 15.92 | 0.06098 | 261 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, xanthine |
| xanthine phosphoribosyltransferase (LdXPRT)variant Y208F | Leishmania donovani | 5-phospho-alpha-D-ribose 1-diphosphate1.0 mM xanthine; cosubstrate xanthine | 0.81 | 0.01954 | 41.4 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, 5-phospho-alpha-D-ribose 1-diphosphate |
| xanthine phosphoribosyltransferase (LdXPRT)variant Y208F | Leishmania donovani | 5-phospho-alpha-D-ribose 1-diphosphate1.0 mM hypoxanthine; cosubstrate hypoxanthine | 1.1 | 0.03253 | 33.8 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, 5-phospho-alpha-D-ribose 1-diphosphate |
| xanthine phosphoribosyltransferase (LdXPRT)variant Y208F | Leishmania donovani | guanine | 0.308 | 0.05703 | 5.4 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, guanine |
| xanthine phosphoribosyltransferase (LdXPRT)variant Y208F | Leishmania donovani | hypoxanthine | 0.577 | 0.08221 | 7 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, hypoxanthine |
| xanthine phosphoribosyltransferase (LdXPRT)variant Y208F | Leishmania donovani | xanthine | 1.126 | 0.02554 | 44 | pH 7 | Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, xanthine |