EC 2.4.2.8: hypoxanthine phosphoribosyltransferase

TransferasesOpen in Browse

CatLog read 160 records for EC 2.4.2.8 from 12 papers, for 7 organisms. Names in these papers: hypoxanthine phosphoribosyltransferase (HPRT), hypoxanthine-guanine phosphoribosyltransferase (HGPRT), hypoxanthine guanine phosphoribosyltransferase (HGPRT), xanthine phosphoribosyltransferase (LdXPRT) and 6 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 104 records for EC 2.4.2.8 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.4.2.8 in Browse.

Papers

Papers with records for EC 2.4.2.8
Paper	Organisms	Records
A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity	Homo sapiens, Plasmodium falciparum	32
Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase	Trypanosoma cruzi	23
Ile209 of Leishmania donovani xanthine phosphoribosyltransferase plays a key role in determining its purine base specificity	Leishmania donovani	20
Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase	Homo sapiens, Plasmodium falciparum	17
Role of the flexible loop of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus in enzyme catalysis	Tritrichomonas foetus	12
Cloning, purification, and characterization of thermostable hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis	Thermoanaerobacter tengcongensis	12
Biochemical and structural characterization of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Pyrococcus horikoshii	Pyrococcus horikoshii	12
Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes	Homo sapiens	9
Saturation mutagenesis, complement selection, and steady-state kinetic studies illuminate the roles of invariant residues in active site loop I of the hypoxanthine phosphoribosyltransferase from…	Trypanosoma cruzi	9
Steady-state kinetics of the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi	Trypanosoma cruzi	8
Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase	Leishmania donovani	3
Investigation of the functional hot-spot residues of an enzyme by real-time monitoring of the enzymatic reaction using NMR and computational approaches	Homo sapiens	3

Records

Records for EC 2.4.2.8 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
human hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	guanine	14	—	—	pH 7.4, 23 °C	PMID 26902413	Open record: human hypoxanthine-guanine phosphoribosyltransferase (HGPRT), guanine
human hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	hypoxanthine	6.3	—	—	pH 7.4, 23 °C	PMID 26902413	Open record: human hypoxanthine-guanine phosphoribosyltransferase (HGPRT), hypoxanthine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	guanine	25.5	0.0045	5.7 × 10³	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT), guanine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	hypoxanthine	7.1	0.0014	5.2 × 10³	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT), hypoxanthine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	PRPPIMP formation followed spectrophotometrically at 245 nm	—	0.0351	200	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT), PRPP
hypoxanthine guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	PRPPGMP formation followed spectrophotometrically at 257.5 nm	—	0.0755	300	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT), PRPP
hypoxanthine guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	xanthine	0.007	—	—	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT), xanthine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36G	Homo sapiens	guanine	3.4	0.0061	600	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36G, guanine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36G	Homo sapiens	hypoxanthine	3.1	0.0018	1.7 × 10³	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36G, hypoxanthine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36G	Homo sapiens	PRPPIMP formation followed spectrophotometrically at 245 nm	—	0.011	400	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36G, PRPP
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36G	Homo sapiens	PRPPGMP formation followed spectrophotometrically at 257.5 nm	—	0.0498	70	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36G, PRPP
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36G	Homo sapiens	xanthine	0.023	—	—	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36G, xanthine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36K	Homo sapiens	guanine	6.3	0.0029	2.2 × 10³	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36K, guanine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36K	Homo sapiens	hypoxanthine	3.4	0.0016	2.1 × 10³	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36K, hypoxanthine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36K	Homo sapiens	PRPPIMP formation followed spectrophotometrically at 245 nm	—	0.0044	800	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36K, PRPP
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36K	Homo sapiens	PRPPGMP formation followed spectrophotometrically at 257.5 nm	—	0.0289	200	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36K, PRPP
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36K	Homo sapiens	xanthine	0.027	—	—	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36K, xanthine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36L	Homo sapiens	guanine	18	0.002	9 × 10³	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36L, guanine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36L	Homo sapiens	hypoxanthine	5.4	0.0044	1.2 × 10³	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36L, hypoxanthine
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36L	Homo sapiens	PRPPIMP formation followed spectrophotometrically at 245 nm	—	0.027	200	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36L, PRPP
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36L	Homo sapiens	PRPPGMP formation followed spectrophotometrically at 257.5 nm	—	0.041	400	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36L, PRPP
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36L	Homo sapiens	xanthine	0.07	0.2865	0.24	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (HGPRT) variant F36L, xanthine
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2A	Plasmodium falciparum	guanine	1.1	—	—	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant L44F/P2A, guanine
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2A	Plasmodium falciparum	hypoxanthine	0.94	—	—	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant L44F/P2A, hypoxanthine
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2A	Plasmodium falciparum	PRPPIMP formation followed spectrophotometrically at 245 nm	—	0.1019	9	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant L44F/P2A, PRPP
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2A	Plasmodium falciparum	PRPPGMP formation followed spectrophotometrically at 257.5 nm	—	0.116	9	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant L44F/P2A, PRPP
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2A	Plasmodium falciparum	PRPPXMP formation followed spectrophotometrically at 255 nm	—	0.151	8	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant L44F/P2A, PRPP
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2A	Plasmodium falciparum	xanthine	1.2	0.853	1.4	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant L44F/P2A, xanthine
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2A	Plasmodium falciparum	guanine	1.2	—	—	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant P2A, guanine
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2A	Plasmodium falciparum	hypoxanthine	1.13	—	—	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant P2A, hypoxanthine
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2A	Plasmodium falciparum	PRPPIMP formation followed spectrophotometrically at 245 nm	—	0.0297	30	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant P2A, PRPP
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2A	Plasmodium falciparum	PRPPGMP formation followed spectrophotometrically at 257.5 nm	—	0.201	6	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant P2A, PRPP
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2A	Plasmodium falciparum	PRPPXMP formation followed spectrophotometrically at 255 nm	—	0.0789	40	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant P2A, PRPP
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2A	Plasmodium falciparum	xanthine	2.9	0.261	10	pH 7.4	PMID 15178494	Open record: hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) variant P2A, xanthine
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	5-phospho-alpha-D-ribosyl 1-pyrophosphateforward reaction (IMP formation, A245); cosubstrate Hx	23.2	0.0308	750	pH 7.5, 37 °C	PMID 15210120	Open record: hypoxanthine phosphoribosyltransferase (HPRT), 5-phospho-alpha-D-ribosyl 1-pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	5-phospho-alpha-D-ribosyl 1-pyrophosphateforward reaction (GMP formation, A257.5); cosubstrate G	32.2	0.0318	1.01 × 10³	pH 7.5, 37 °C	PMID 15210120	Open record: hypoxanthine phosphoribosyltransferase (HPRT), 5-phospho-alpha-D-ribosyl 1-pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	5-phospho-α-D-ribosyl-1-pyrophosphate	23	0.0324	720	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT), 5-phospho-α-D-ribosyl-1-pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	guanine	32.9	0.0124	2.65 × 10³	pH 7.5, 37 °C	PMID 15210120	Open record: hypoxanthine phosphoribosyltransferase (HPRT), guanine
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	guanosine monophosphate	0.087	0.0294	3	pH 7.5, 37 °C	PMID 15210120	Open record: hypoxanthine phosphoribosyltransferase (HPRT), guanosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	hypoxanthine	23	0.0086	2.66 × 10³	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT), hypoxanthine
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	hypoxanthine	22.9	0.00863	2.65 × 10³	pH 7.5, 37 °C	PMID 15210120	Open record: hypoxanthine phosphoribosyltransferase (HPRT), hypoxanthine
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	inosine monophosphate	0.47	0.0266	17.7	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT), inosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	inosine monophosphate	0.463	0.0163	28.4	pH 7.5, 37 °C	PMID 15210120	Open record: hypoxanthine phosphoribosyltransferase (HPRT), inosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	pyrophosphate	0.48	0.0345	13.9	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT), pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	pyrophosphatereverse reaction (IMP pyrophosphorolysis); cosubstrate IMP	0.473	0.0162	29.2	pH 7.5, 37 °C	PMID 15210120	Open record: hypoxanthine phosphoribosyltransferase (HPRT), pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)	Trypanosoma cruzi	pyrophosphatereverse reaction (GMP pyrophosphorolysis); cosubstrate GMP	0.095	0.0218	4.4	pH 7.5, 37 °C	PMID 15210120	Open record: hypoxanthine phosphoribosyltransferase (HPRT), pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant G69S	Trypanosoma cruzi	guanine	22.1	0.0218	1.02 × 10³	pH 7.5, 37 °C	PMID 15158715	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, guanine
hypoxanthine phosphoribosyltransferase (HPRT)variant G69S	Trypanosoma cruzi	hypoxanthine	22	0.0339	650	pH 7.5, 37 °C	PMID 15158715	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, hypoxanthine
hypoxanthine phosphoribosyltransferase (HPRT)variant G69S	Trypanosoma cruzi	inosine monophosphate	0.19	0.0798	2.34	pH 7.5, 37 °C	PMID 15158715	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, inosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant G69S	Trypanosoma cruzi	phosphoribosylpyrophosphate	20	0.0834	240	pH 7.5, 37 °C	PMID 15158715	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, phosphoribosylpyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant G69S	Trypanosoma cruzi	pyrophosphate	0.31	0.2135	1.44	pH 7.5, 37 °C	PMID 15158715	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68D	Trypanosoma cruzi	5-phospho-α-D-ribosyl-1-pyrophosphate	21	0.224	94	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68D, 5-phospho-α-D-ribosyl-1-pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68D	Trypanosoma cruzi	hypoxanthine	22	0.0381	580	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68D, hypoxanthine
hypoxanthine phosphoribosyltransferase (HPRT)variant K68D	Trypanosoma cruzi	inosine monophosphate	0.003	0.0314	0.096	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68D, inosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68E	Trypanosoma cruzi	5-phospho-α-D-ribosyl-1-pyrophosphate	44	0.483	91	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68E, 5-phospho-α-D-ribosyl-1-pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68E	Trypanosoma cruzi	hypoxanthine	39	0.0443	880	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68E, hypoxanthine
hypoxanthine phosphoribosyltransferase (HPRT)variant K68E	Trypanosoma cruzi	inosine monophosphate	0.002	0.106	0.019	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68E, inosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68E	Trypanosoma cruzi	pyrophosphate	0.002	0.0484	0.041	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68E, pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68N	Trypanosoma cruzi	5-phospho-α-D-ribosyl-1-pyrophosphate	3.8	0.0226	170	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68N, 5-phospho-α-D-ribosyl-1-pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68N	Trypanosoma cruzi	hypoxanthine	4.5	0.0537	84	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68N, hypoxanthine
hypoxanthine phosphoribosyltransferase (HPRT)variant K68N	Trypanosoma cruzi	inosine monophosphate	0.02	0.253	0.079	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68N, inosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68N	Trypanosoma cruzi	pyrophosphate	0.018	0.0796	0.23	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68N, pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68P	Trypanosoma cruzi	5-phospho-α-D-ribosyl-1-pyrophosphate	2	0.0207	97	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68P, 5-phospho-α-D-ribosyl-1-pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68P	Trypanosoma cruzi	hypoxanthine	2.3	0.0611	37	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68P, hypoxanthine
hypoxanthine phosphoribosyltransferase (HPRT)variant K68P	Trypanosoma cruzi	inosine monophosphate	0.007	0.0539	0.13	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68P, inosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68P	Trypanosoma cruzi	pyrophosphate	0.008	0.0949	0.08	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68P, pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68R	Trypanosoma cruzi	5-phospho-α-D-ribosyl-1-pyrophosphate	12	0.097	120	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68R, 5-phospho-α-D-ribosyl-1-pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68R	Trypanosoma cruzi	hypoxanthine	12	0.009	1.3 × 10³	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68R, hypoxanthine
hypoxanthine phosphoribosyltransferase (HPRT)variant K68R	Trypanosoma cruzi	inosine monophosphate	0.53	7.4	0.072	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68R, inosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant K68R	Trypanosoma cruzi	pyrophosphate	0.4	0.0264	15.2	pH 7.5, 37 °C	PMID 14698288	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68R, pyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant L67M	Trypanosoma cruzi	hypoxanthine	5.68	0.0192	295	pH 7.5, 37 °C	PMID 15158715	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant L67M, hypoxanthine
hypoxanthine phosphoribosyltransferase (HPRT)variant L67M	Trypanosoma cruzi	inosine monophosphate	0.07	0.0266	3	pH 7.5, 37 °C	PMID 15158715	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant L67M, inosine monophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant L67M	Trypanosoma cruzi	phosphoribosylpyrophosphate	4.7	0.132	35	pH 7.5, 37 °C	PMID 15158715	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant L67M, phosphoribosylpyrophosphate
hypoxanthine phosphoribosyltransferase (HPRT)variant L67M	Trypanosoma cruzi	pyrophosphate	0.12	0.1354	0.92	pH 7.5, 37 °C	PMID 15158715	Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant L67M, pyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	favipiravir	0.617	22.6	0.0273 calc.	25 °C	PMID 41530325	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), favipiravir
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	guanine	10.48	0.004533	2311	pH 7.4	PMID 10833458	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), guanine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	hypoxanthine	5.7	0.001036	5502	pH 7.4	PMID 10833458	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), hypoxanthine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	phosphoribosylpyrophosphate245 nm (hypoxanthine to IMP); cosubstrate hypoxanthine	—	0.03288	173	pH 7.4	PMID 10833458	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), phosphoribosylpyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Homo sapiens	phosphoribosylpyrophosphate257.5 nm (guanine to GMP); cosubstrate guanine	—	0.0731	143	pH 7.4	PMID 10833458	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), phosphoribosylpyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)chimera DS1	Homo sapiens	guanine	0.013	0.001141	11	pH 7.4	PMID 10833458	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT) chimera DS1, guanine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)chimera DS1	Homo sapiens	hypoxanthine	0.073	0.001452	50	pH 7.4	PMID 10833458	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT) chimera DS1, hypoxanthine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)chimera DS1	Homo sapiens	phosphoribosylpyrophosphate245 nm (hypoxanthine to IMP); cosubstrate hypoxanthine	—	0.4444	0.164	pH 7.4	PMID 10833458	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT) chimera DS1, phosphoribosylpyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)chimera DS1	Homo sapiens	phosphoribosylpyrophosphate257.5 nm (guanine to GMP); cosubstrate guanine	—	0.3181	0.0408	pH 7.4	PMID 10833458	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT) chimera DS1, phosphoribosylpyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)chimera DS1	Homo sapiens	xanthine	0.062	—	—	pH 7.4	PMID 10833458	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT) chimera DS1, xanthine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)variant K140M	Homo sapiens	favipiravir	0.315	9.44	0.0334 calc.	25 °C	PMID 41530325	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT) variant K140M, favipiravir
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)variant T138A	Homo sapiens	favipiravir	2.47	10.7	0.231 calc.	25 °C	PMID 41530325	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT) variant T138A, favipiravir
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	5-phospho-alpha-D-ribosyl-1-pyrophosphateIMP formation followed at 245 nm; cosubstrate hypoxanthine	—	0.123	33	pH 7.4, 25 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	5-phospho-alpha-D-ribosyl-1-pyrophosphateIMP formation followed at 245 nm; cosubstrate hypoxanthine	—	0.119	67	pH 7.4, 37 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	5-phospho-alpha-D-ribosyl-1-pyrophosphateIMP formation followed at 245 nm; cosubstrate hypoxanthine	—	0.138	115	pH 7.4, 50 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	5-phospho-alpha-D-ribosyl-1-pyrophosphateGMP formation followed at 257 nm; cosubstrate guanine	—	0.125	16	pH 7.4, 25 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	5-phospho-alpha-D-ribosyl-1-pyrophosphateGMP formation followed at 257 nm; cosubstrate guanine	—	0.116	34	pH 7.4, 37 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	5-phospho-alpha-D-ribosyl-1-pyrophosphateGMP formation followed at 257 nm; cosubstrate guanine	—	0.112	73	pH 7.4, 50 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	guanine	2.04	0.0036	560	pH 7.4, 25 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), guanine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	guanine	3.98	0.0042	940	pH 7.4, 37 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), guanine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	guanine	8.16	0.0032	2.54 × 10³	pH 7.4, 50 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), guanine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	hypoxanthine	4.12	0.0024	1.75 × 10³	pH 7.4, 25 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), hypoxanthine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	hypoxanthine	7.97	0.0033	2.51 × 10³	pH 7.4, 37 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), hypoxanthine
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)	Thermoanaerobacter tengcongensis	hypoxanthine	15.9	0.0027	5.94 × 10³	pH 7.4, 50 °C	PMID 14965769	Open record: hypoxanthine-guanine phosphoribosyltransferase (HGPRT), hypoxanthine
hypoxanthine-guanine phosphoribosyltransferase (LdHGPRT)variant D168E	Leishmania donovani	guanine	5.4	0.0059	920 calc.	pH 7.5, 25 °C	PMID 19861168	Open record: hypoxanthine-guanine phosphoribosyltransferase (LdHGPRT) variant D168E, guanine
hypoxanthine-guanine phosphoribosyltransferase (LdHGPRT)variant D168E	Leishmania donovani	hypoxanthine	3	8 × 10⁻⁴	3.8 × 10³ calc.	pH 7.5, 25 °C	PMID 19861168	Open record: hypoxanthine-guanine phosphoribosyltransferase (LdHGPRT) variant D168E, hypoxanthine
hypoxanthine-guanine phosphoribosyltransferase (LdHGPRT)variant D185E	Leishmania donovani	hypoxanthine	0.07	0.0149	4.7 calc.	pH 7.5, 25 °C	PMID 19861168	Open record: hypoxanthine-guanine phosphoribosyltransferase (LdHGPRT) variant D185E, hypoxanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)	Tritrichomonas foetus	alpha-D-5-phosphoribosyl-1-pyrophosphate	—	0.046	—	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase), alpha-D-5-phosphoribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)	Tritrichomonas foetus	guanine	2.5	0.0024	1.0 × 10³ calc.	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase), guanine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant S73A	Tritrichomonas foetus	alpha-D-5-phosphoribosyl-1-pyrophosphate	—	0.1941	—	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant S73A, alpha-D-5-phosphoribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant S73A	Tritrichomonas foetus	guanine	2.3	0.0112	210 calc.	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant S73A, guanine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant S75H	Tritrichomonas foetus	alpha-D-5-phosphoribosyl-1-pyrophosphate	—	0.0287	—	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant S75H, alpha-D-5-phosphoribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant S75H	Tritrichomonas foetus	guanine	3.3	0.0029	1.1 × 10³ calc.	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant S75H, guanine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant Y74E	Tritrichomonas foetus	alpha-D-5-phosphoribosyl-1-pyrophosphate	—	0.2068	—	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant Y74E, alpha-D-5-phosphoribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant Y74E	Tritrichomonas foetus	guanine	1.5	0.0164	91 calc.	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant Y74E, guanine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant Y74F	Tritrichomonas foetus	alpha-D-5-phosphoribosyl-1-pyrophosphate	—	0.1385	—	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant Y74F, alpha-D-5-phosphoribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant Y74F	Tritrichomonas foetus	guanine	1.8	0.0145	120 calc.	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant Y74F, guanine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant Y74W	Tritrichomonas foetus	alpha-D-5-phosphoribosyl-1-pyrophosphate	—	0.0412	—	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant Y74W, alpha-D-5-phosphoribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase)variant Y74W	Tritrichomonas foetus	guanine	3.1	0.0043	720 calc.	pH 7, 37 °C	PMID 11284686	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase) variant Y74W, guanine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	5-phospho-alpha-D-ribosyl-1-pyrophosphateunactivated PfHGXPRT; post-lag linear phase	—	0.72	0.42	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	5-phospho-alpha-D-ribosyl-1-pyrophosphateIMP activated PfHGXPRT (pre-incubated with IMP)	—	0.028	43	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	guanine	0.3	—	—	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), guanine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	hypoxanthine	0.4	—	—	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), hypoxanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	inorganic pyrophosphate-Mg2+ complexunactivated PfHGXPRT	—	0.0039	0.9	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inorganic pyrophosphate-Mg2+ complex
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	inorganic pyrophosphate-Mg2+ complexIMP activated PfHGXPRT	—	0.0042	1	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inorganic pyrophosphate-Mg2+ complex
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	inorganic pyrophosphate-Mg2+ complexPRPP.Mg2+ activated PfHGXPRT	—	0.02	0.2	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inorganic pyrophosphate-Mg2+ complex
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	inosine 5'-monophosphateunactivated PfHGXPRT; IMP pyrophosphorolysis	0.0036	0.0016	2.2	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	inosine 5'-monophosphateIMP activated PfHGXPRT; IMP pyrophosphorolysis	0.0042	—	0.6	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	inosine 5'-monophosphatePRPP.Mg2+ activated PfHGXPRT; IMP pyrophosphorolysis	0.004	0.006	0.7	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	inosine 5'-monophosphateunactivated PfHGXPRT; IMP pyrophosphorolysis stopped-flow	0.003	—	—	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	inosine 5'-monophosphateIMP activated PfHGXPRT; IMP pyrophosphorolysis stopped-flow	0.003	—	—	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	inosine 5'-monophosphateactivated (cis-tetramer) PfHGXPRT; IMP pyrophosphorolysis	0.0039	—	—	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	xanthineunactivated PfHGXPRT; post-lag linear phase	0.3	0.052	5.8	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), xanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT)	Plasmodium falciparum	xanthineIMP activated PfHGXPRT (pre-incubated with IMP)	1.2	0.09	13	pH 7.4, 23 °C	PMID 26902413	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), xanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	guanine	0.212	0.00485	43.7	pH 7.5, 50 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), guanine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	guanine	1.428	0.00326	438.5	pH 7.5, 70 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), guanine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	hypoxanthine	0.375	0.00388	96.5	pH 7.5, 40 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), hypoxanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	hypoxanthine	0.828	0.00702	118	pH 7.5, 50 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), hypoxanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	hypoxanthine	1.383	0.00483	286.5	pH 7.5, 60 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), hypoxanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	hypoxanthine	3.158	0.0061	517.8	pH 7.5, 70 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), hypoxanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	xanthine	0.678	0.1012	6.7	pH 7.5, 50 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), xanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	xanthine	2.197	0.095	23.2	pH 7.5, 70 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), xanthine
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	α-D-phosphoribosyl-1-pyrophosphate	0.662	0.0428	15.5	pH 7.5, 40 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), α-D-phosphoribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	α-D-phosphoribosyl-1-pyrophosphate	0.475	0.0412	11.5	pH 7.5, 50 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), α-D-phosphoribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	α-D-phosphoribosyl-1-pyrophosphate	1.678	0.0282	59.5	pH 7.5, 60 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), α-D-phosphoribosyl-1-pyrophosphate
hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT)	Pyrococcus horikoshii	α-D-phosphoribosyl-1-pyrophosphate	3.05	0.0369	82.7	pH 7.5, 70 °C	PMID 18405676	Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PhHGXPRT), α-D-phosphoribosyl-1-pyrophosphate
xanthine phosphoribosyltransferase (LdXPRT)	Leishmania donovani	5-phospho-alpha-D-ribose 1-diphosphate1.0 mM xanthine; cosubstrate xanthine	2	0.01885	106	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT), 5-phospho-alpha-D-ribose 1-diphosphate
xanthine phosphoribosyltransferase (LdXPRT)	Leishmania donovani	5-phospho-alpha-D-ribose 1-diphosphate1.0 mM hypoxanthine; cosubstrate hypoxanthine	1.3	0.04176	31.1	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT), 5-phospho-alpha-D-ribose 1-diphosphate
xanthine phosphoribosyltransferase (LdXPRT)	Leishmania donovani	guanine	0.455	0.1037	4.3	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT), guanine
xanthine phosphoribosyltransferase (LdXPRT)	Leishmania donovani	hypoxanthine	1.1	0.2042	5.3	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT), hypoxanthine
xanthine phosphoribosyltransferase (LdXPRT)	Leishmania donovani	xanthine	1.8	0.0089	202.2	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT), xanthine
xanthine phosphoribosyltransferase (LdXPRT)variant I209V	Leishmania donovani	5-phospho-alpha-D-ribose 1-diphosphate1.0 mM xanthine; cosubstrate xanthine	4.38	0.0299	146	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, 5-phospho-alpha-D-ribose 1-diphosphate
xanthine phosphoribosyltransferase (LdXPRT)variant I209V	Leishmania donovani	5-phospho-alpha-D-ribose 1-diphosphate1.0 mM hypoxanthine; cosubstrate hypoxanthine	1.21	0.03576	33.8	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, 5-phospho-alpha-D-ribose 1-diphosphate
xanthine phosphoribosyltransferase (LdXPRT)variant I209V	Leishmania donovani	guanine	0.518	0.0373	13.8	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, guanine
xanthine phosphoribosyltransferase (LdXPRT)variant I209V	Leishmania donovani	hypoxanthine	1.23	0.04862	25.2	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, hypoxanthine
xanthine phosphoribosyltransferase (LdXPRT)variant I209V	Leishmania donovani	xanthine	4.19	0.06662	62.8	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V, xanthine
xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D	Leishmania donovani	5-phospho-alpha-D-ribose 1-diphosphate1.0 mM xanthine; cosubstrate xanthine	13.29	0.03669	362.2	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, 5-phospho-alpha-D-ribose 1-diphosphate
xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D	Leishmania donovani	5-phospho-alpha-D-ribose 1-diphosphate1.0 mM hypoxanthine; cosubstrate hypoxanthine	7.99	0.02257	354	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, 5-phospho-alpha-D-ribose 1-diphosphate
xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D	Leishmania donovani	guanine	8.68	0.01441	602.3	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, guanine
xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D	Leishmania donovani	hypoxanthine	9.89	0.02649	373.3	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, hypoxanthine
xanthine phosphoribosyltransferase (LdXPRT)variant I209V/E215D	Leishmania donovani	xanthine	15.92	0.06098	261	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant I209V/E215D, xanthine
xanthine phosphoribosyltransferase (LdXPRT)variant Y208F	Leishmania donovani	5-phospho-alpha-D-ribose 1-diphosphate1.0 mM xanthine; cosubstrate xanthine	0.81	0.01954	41.4	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, 5-phospho-alpha-D-ribose 1-diphosphate
xanthine phosphoribosyltransferase (LdXPRT)variant Y208F	Leishmania donovani	5-phospho-alpha-D-ribose 1-diphosphate1.0 mM hypoxanthine; cosubstrate hypoxanthine	1.1	0.03253	33.8	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, 5-phospho-alpha-D-ribose 1-diphosphate
xanthine phosphoribosyltransferase (LdXPRT)variant Y208F	Leishmania donovani	guanine	0.308	0.05703	5.4	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, guanine
xanthine phosphoribosyltransferase (LdXPRT)variant Y208F	Leishmania donovani	hypoxanthine	0.577	0.08221	7	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, hypoxanthine
xanthine phosphoribosyltransferase (LdXPRT)variant Y208F	Leishmania donovani	xanthine	1.126	0.02554	44	pH 7	PMID 34268726	Open record: xanthine phosphoribosyltransferase (LdXPRT) variant Y208F, xanthine