CatLogenzyme kinetics catalog

Values CatLog read from this paper

A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity

PMID 15178494doi:10.1016/j.abb.2004.04.014Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 32 records (68 values) from this paper: hypoxanthine guanine phosphoribosyltransferase (HGPRT), hypoxanthine guanine phosphoribosyltransferase (PfHGPRT) from Homo sapiens, Plasmodium falciparum.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.4.2.8

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
hypoxanthine guanine phosphoribosyltransferase (HGPRT)Homo sapiensguanine25.50.00455.7 × 10³pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)Homo sapienshypoxanthine7.10.00145.2 × 10³pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)Homo sapiensPRPPIMP formation followed spectrophotometrically at 245 nm—0.0351200pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)Homo sapiensPRPPGMP formation followed spectrophotometrically at 257.5 nm—0.0755300pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)Homo sapiensxanthine0.007——pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36GHomo sapiensguanine3.40.0061600pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36GHomo sapienshypoxanthine3.10.00181.7 × 10³pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36GHomo sapiensPRPPIMP formation followed spectrophotometrically at 245 nm—0.011400pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36GHomo sapiensPRPPGMP formation followed spectrophotometrically at 257.5 nm—0.049870pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36GHomo sapiensxanthine0.023——pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36KHomo sapiensguanine6.30.00292.2 × 10³pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36KHomo sapienshypoxanthine3.40.00162.1 × 10³pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36KHomo sapiensPRPPIMP formation followed spectrophotometrically at 245 nm—0.0044800pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36KHomo sapiensPRPPGMP formation followed spectrophotometrically at 257.5 nm—0.0289200pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36KHomo sapiensxanthine0.027——pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36LHomo sapiensguanine180.0029 × 10³pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36LHomo sapienshypoxanthine5.40.00441.2 × 10³pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36LHomo sapiensPRPPIMP formation followed spectrophotometrically at 245 nm—0.027200pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36LHomo sapiensPRPPGMP formation followed spectrophotometrically at 257.5 nm—0.041400pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (HGPRT)variant F36LHomo sapiensxanthine0.070.28650.24pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2APlasmodium falciparumguanine1.1——pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2APlasmodium falciparumhypoxanthine0.94——pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2APlasmodium falciparumPRPPIMP formation followed spectrophotometrically at 245 nm—0.10199pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2APlasmodium falciparumPRPPGMP formation followed spectrophotometrically at 257.5 nm—0.1169pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2APlasmodium falciparumPRPPXMP formation followed spectrophotometrically at 255 nm—0.1518pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant L44F/P2APlasmodium falciparumxanthine1.20.8531.4pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2APlasmodium falciparumguanine1.2——pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2APlasmodium falciparumhypoxanthine1.13——pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2APlasmodium falciparumPRPPIMP formation followed spectrophotometrically at 245 nm—0.029730pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2APlasmodium falciparumPRPPGMP formation followed spectrophotometrically at 257.5 nm—0.2016pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2APlasmodium falciparumPRPPXMP formation followed spectrophotometrically at 255 nm—0.078940pH 7.4Open
hypoxanthine guanine phosphoribosyltransferase (PfHGPRT)variant P2APlasmodium falciparumxanthine2.90.26110pH 7.4Open