Values CatLog read from this paper
Saturation mutagenesis, complement selection, and steady-state kinetic studies illuminate the roles of invariant residues in active site loop I of the hypoxanthine phosphoribosyltransferase from…
PMID 15158715doi:10.1016/j.bbapap.2004.01.006Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 9 records (27 values) from this paper: hypoxanthine phosphoribosyltransferase (HPRT) from Trypanosoma cruzi.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| hypoxanthine phosphoribosyltransferase (HPRT)variant G69S | Trypanosoma cruzi | guanine | 22.1 | 0.0218 | 1.02 × 10³ | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, guanine |
| hypoxanthine phosphoribosyltransferase (HPRT)variant G69S | Trypanosoma cruzi | hypoxanthine | 22 | 0.0339 | 650 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, hypoxanthine |
| hypoxanthine phosphoribosyltransferase (HPRT)variant G69S | Trypanosoma cruzi | inosine monophosphate | 0.19 | 0.0798 | 2.34 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, inosine monophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant G69S | Trypanosoma cruzi | phosphoribosylpyrophosphate | 20 | 0.0834 | 240 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, phosphoribosylpyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant G69S | Trypanosoma cruzi | pyrophosphate | 0.31 | 0.2135 | 1.44 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant G69S, pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant L67M | Trypanosoma cruzi | hypoxanthine | 5.68 | 0.0192 | 295 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant L67M, hypoxanthine |
| hypoxanthine phosphoribosyltransferase (HPRT)variant L67M | Trypanosoma cruzi | inosine monophosphate | 0.07 | 0.0266 | 3 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant L67M, inosine monophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant L67M | Trypanosoma cruzi | phosphoribosylpyrophosphate | 4.7 | 0.132 | 35 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant L67M, phosphoribosylpyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant L67M | Trypanosoma cruzi | pyrophosphate | 0.12 | 0.1354 | 0.92 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant L67M, pyrophosphate |