Values CatLog read from this paper
Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase
PMID 26902413doi:10.1016/j.molbiopara.2016.02.006Open in Browse
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CatLog read 17 records (31 values) from this paper: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) from Plasmodium falciparum, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) | Homo sapiens | guanine | 14 | — | — | pH 7.4, 23 °C | Open record: human hypoxanthine-guanine phosphoribosyltransferase (HGPRT), guanine |
| human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) | Homo sapiens | hypoxanthine | 6.3 | — | — | pH 7.4, 23 °C | Open record: human hypoxanthine-guanine phosphoribosyltransferase (HGPRT), hypoxanthine |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | 5-phospho-alpha-D-ribosyl-1-pyrophosphateunactivated PfHGXPRT; post-lag linear phase | — | 0.72 | 0.42 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | 5-phospho-alpha-D-ribosyl-1-pyrophosphateIMP activated PfHGXPRT (pre-incubated with IMP) | — | 0.028 | 43 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), 5-phospho-alpha-D-ribosyl-1-pyrophosphate |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | guanine | 0.3 | — | — | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), guanine |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | hypoxanthine | 0.4 | — | — | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), hypoxanthine |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | inorganic pyrophosphate-Mg2+ complexunactivated PfHGXPRT | — | 0.0039 | 0.9 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inorganic pyrophosphate-Mg2+ complex |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | inorganic pyrophosphate-Mg2+ complexIMP activated PfHGXPRT | — | 0.0042 | 1 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inorganic pyrophosphate-Mg2+ complex |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | inorganic pyrophosphate-Mg2+ complexPRPP.Mg2+ activated PfHGXPRT | — | 0.02 | 0.2 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inorganic pyrophosphate-Mg2+ complex |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | inosine 5'-monophosphateunactivated PfHGXPRT; IMP pyrophosphorolysis | 0.0036 | 0.0016 | 2.2 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | inosine 5'-monophosphateIMP activated PfHGXPRT; IMP pyrophosphorolysis | 0.0042 | — | 0.6 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | inosine 5'-monophosphatePRPP.Mg2+ activated PfHGXPRT; IMP pyrophosphorolysis | 0.004 | 0.006 | 0.7 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | inosine 5'-monophosphateunactivated PfHGXPRT; IMP pyrophosphorolysis stopped-flow | 0.003 | — | — | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | inosine 5'-monophosphateIMP activated PfHGXPRT; IMP pyrophosphorolysis stopped-flow | 0.003 | — | — | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | inosine 5'-monophosphateactivated (cis-tetramer) PfHGXPRT; IMP pyrophosphorolysis | 0.0039 | — | — | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), inosine 5'-monophosphate |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | xanthineunactivated PfHGXPRT; post-lag linear phase | 0.3 | 0.052 | 5.8 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), xanthine |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) | Plasmodium falciparum | xanthineIMP activated PfHGXPRT (pre-incubated with IMP) | 1.2 | 0.09 | 13 | pH 7.4, 23 °C | Open record: hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), xanthine |