Values CatLog read from this paper
Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase
PMID 14698288doi:10.1016/j.jmb.2003.11.012Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 23 records (69 values) from this paper: hypoxanthine phosphoribosyltransferase (HPRT) from Trypanosoma cruzi.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| hypoxanthine phosphoribosyltransferase (HPRT) | Trypanosoma cruzi | 5-phospho-α-D-ribosyl-1-pyrophosphate | 23 | 0.0324 | 720 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT), 5-phospho-α-D-ribosyl-1-pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT) | Trypanosoma cruzi | hypoxanthine | 23 | 0.0086 | 2.66 × 10³ | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT), hypoxanthine |
| hypoxanthine phosphoribosyltransferase (HPRT) | Trypanosoma cruzi | inosine monophosphate | 0.47 | 0.0266 | 17.7 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT), inosine monophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT) | Trypanosoma cruzi | pyrophosphate | 0.48 | 0.0345 | 13.9 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT), pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68D | Trypanosoma cruzi | 5-phospho-α-D-ribosyl-1-pyrophosphate | 21 | 0.224 | 94 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68D, 5-phospho-α-D-ribosyl-1-pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68D | Trypanosoma cruzi | hypoxanthine | 22 | 0.0381 | 580 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68D, hypoxanthine |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68D | Trypanosoma cruzi | inosine monophosphate | 0.003 | 0.0314 | 0.096 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68D, inosine monophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68E | Trypanosoma cruzi | 5-phospho-α-D-ribosyl-1-pyrophosphate | 44 | 0.483 | 91 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68E, 5-phospho-α-D-ribosyl-1-pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68E | Trypanosoma cruzi | hypoxanthine | 39 | 0.0443 | 880 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68E, hypoxanthine |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68E | Trypanosoma cruzi | inosine monophosphate | 0.002 | 0.106 | 0.019 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68E, inosine monophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68E | Trypanosoma cruzi | pyrophosphate | 0.002 | 0.0484 | 0.041 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68E, pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68N | Trypanosoma cruzi | 5-phospho-α-D-ribosyl-1-pyrophosphate | 3.8 | 0.0226 | 170 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68N, 5-phospho-α-D-ribosyl-1-pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68N | Trypanosoma cruzi | hypoxanthine | 4.5 | 0.0537 | 84 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68N, hypoxanthine |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68N | Trypanosoma cruzi | inosine monophosphate | 0.02 | 0.253 | 0.079 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68N, inosine monophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68N | Trypanosoma cruzi | pyrophosphate | 0.018 | 0.0796 | 0.23 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68N, pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68P | Trypanosoma cruzi | 5-phospho-α-D-ribosyl-1-pyrophosphate | 2 | 0.0207 | 97 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68P, 5-phospho-α-D-ribosyl-1-pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68P | Trypanosoma cruzi | hypoxanthine | 2.3 | 0.0611 | 37 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68P, hypoxanthine |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68P | Trypanosoma cruzi | inosine monophosphate | 0.007 | 0.0539 | 0.13 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68P, inosine monophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68P | Trypanosoma cruzi | pyrophosphate | 0.008 | 0.0949 | 0.08 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68P, pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68R | Trypanosoma cruzi | 5-phospho-α-D-ribosyl-1-pyrophosphate | 12 | 0.097 | 120 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68R, 5-phospho-α-D-ribosyl-1-pyrophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68R | Trypanosoma cruzi | hypoxanthine | 12 | 0.009 | 1.3 × 10³ | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68R, hypoxanthine |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68R | Trypanosoma cruzi | inosine monophosphate | 0.53 | 7.4 | 0.072 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68R, inosine monophosphate |
| hypoxanthine phosphoribosyltransferase (HPRT)variant K68R | Trypanosoma cruzi | pyrophosphate | 0.4 | 0.0264 | 15.2 | pH 7.5, 37 °C | Open record: hypoxanthine phosphoribosyltransferase (HPRT) variant K68R, pyrophosphate |