CatLogenzyme kinetics catalog

Values CatLog read from this paper

Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase

PMID 14592457doi:10.1016/j.abb.2003.09.019Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 28 records (28 values) from this paper: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.141

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)Homo sapiensNAD+—0.0315—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)Homo sapiensprostaglandin E2—0.0063—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant A14S/Q15K/D36S/W37RHomo sapiensNADP+—0.0279—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant A14S/Q15K/D36S/W37RHomo sapiensprostaglandin E2—0.0031—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15KHomo sapiensNAD+—0.0794—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15KHomo sapiensprostaglandin E2—0.0267—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/D36A/W37RHomo sapiensNADP+—0.4587—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/D36A/W37RHomo sapiensprostaglandin E2—0.1031—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/D36S/W37RHomo sapiensNADP+—0.4254—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/D36S/W37RHomo sapiensprostaglandin E2—0.1068—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37KHomo sapiensNAD+—0.037—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37KHomo sapiensprostaglandin E2—0.0131—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37RHomo sapiensNAD+—0.074—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37RHomo sapiensNADP+—0.9145—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37RHomo sapiensprostaglandin E2cosubstrate NAD+—0.0077—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37RHomo sapiensprostaglandin E2cosubstrate NADP+—0.0461—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15RHomo sapiensNAD+—0.0321—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15RHomo sapiensprostaglandin E2—0.0053—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37KHomo sapiensNAD+—0.048—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37KHomo sapiensprostaglandin E2—0.0078—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37RHomo sapiensNAD+—0.0401—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37RHomo sapiensNADP+—0.8922—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37RHomo sapiensprostaglandin E2cosubstrate NAD+—0.0064—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37RHomo sapiensprostaglandin E2cosubstrate NADP+—0.0273—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant W37KHomo sapiensNAD+—0.0482—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant W37KHomo sapiensprostaglandin E2—0.0081—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant W37RHomo sapiensNAD+—0.0289—pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant W37RHomo sapiensprostaglandin E2—0.0064—pH 7.5, 37 °COpen