EC 1.1.1.141: 15-hydroxyprostaglandin dehydrogenase (NAD+)
OxidoreductasesOpen in Browse
CatLog read 77 records for EC 1.1.1.141 from 4 papers, for 3 organisms. Names in these papers: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I), 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 41 records for EC 1.1.1.141 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.141 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase | Homo sapiens | 28 |
| C-Terminal region of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase is involved in the interaction with prostaglandin substrates | Homo sapiens, Mus musculus and 1 more | 24 |
| Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase | Homo sapiens | 18 |
| Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2 | Homo sapiens | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent) | Homo sapiens | nicotinamide adenine dinucleotide (oxidized, NAD+) | — | — | 1.24 × 10³ | pH 7.5, 37 °C | PMID 16828555 | Open record: 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent), nicotinamide adenine dinucleotide (oxidized, NAD+) |
| 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148E | Homo sapiens | nicotinamide adenine dinucleotide (oxidized, NAD+) | 112 | 3.273 | 30 | pH 7.5, 37 °C | PMID 16828555 | Open record: 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent) variant Q148E, nicotinamide adenine dinucleotide (oxidized, NAD+) |
| 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148E | Homo sapiens | prostaglandin E2 | 125 | 0.0258 | 5 × 10³ | pH 7.5, 37 °C | PMID 16828555 | Open record: 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent) variant Q148E, prostaglandin E2 |
| 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148H | Homo sapiens | nicotinamide adenine dinucleotide (oxidized, NAD+) | 266 | 0.342 | 780 | pH 7.5, 37 °C | PMID 16828555 | Open record: 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent) variant Q148H, nicotinamide adenine dinucleotide (oxidized, NAD+) |
| 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148H | Homo sapiens | prostaglandin E2 | 329 | 0.0584 | 6 × 10³ | pH 7.5, 37 °C | PMID 16828555 | Open record: 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent) variant Q148H, prostaglandin E2 |
| 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148N | Homo sapiens | nicotinamide adenine dinucleotide (oxidized, NAD+) | 299 | 0.24 | 1.25 × 10³ | pH 7.5, 37 °C | PMID 16828555 | Open record: 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent) variant Q148N, nicotinamide adenine dinucleotide (oxidized, NAD+) |
| 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148N | Homo sapiens | prostaglandin E2 | 297 | 0.0245 | 1.2 × 10⁴ | pH 7.5, 37 °C | PMID 16828555 | Open record: 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent) variant Q148N, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Homo sapiens | NAD+ | — | 0.0456 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Homo sapiens | NAD+pTYB1 intein fusion expressed in E. coli ER2566 | — | 0.0384 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Homo sapiens | NAD+ | 47 | 0.038 | 1.2 × 10³ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Homo sapiens | prostaglandin E2 | — | 0.0039 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Homo sapiens | prostaglandin E2pTYB1 intein fusion expressed in E. coli ER2566 | — | 0.0043 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Homo sapiens | prostaglandin E2 | 50 | 0.0034 | 1.5 × 10⁴ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Homo sapiens | prostaglandin E2 methyl ester | — | 0.0051 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), prostaglandin E2 methyl ester |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)C-terminal truncate PGDH-255 (last 11 residues deleted) | Homo sapiens | NAD+ | — | 0.0717 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) C-terminal truncate PGDH-255 (last 11 residues deleted), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)C-terminal truncate PGDH-255 (last 11 residues deleted) | Homo sapiens | prostaglandin E2 | — | 0.0169 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) C-terminal truncate PGDH-255 (last 11 residues deleted), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)C-terminal truncate PGDH-255 (last 11 residues deleted) | Homo sapiens | prostaglandin E2 methyl ester | — | 0.0213 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) C-terminal truncate PGDH-255 (last 11 residues deleted), prostaglandin E2 methyl ester |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)C-terminal truncate PGDH-259 (last 7 residues deleted) | Homo sapiens | NAD+ | — | 0.0484 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) C-terminal truncate PGDH-259 (last 7 residues deleted), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)C-terminal truncate PGDH-259 (last 7 residues deleted) | Homo sapiens | prostaglandin E2 | — | 0.0105 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) C-terminal truncate PGDH-259 (last 7 residues deleted), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)C-terminal truncate PGDH-259 (last 7 residues deleted) | Homo sapiens | prostaglandin E2 methyl ester | — | 0.0152 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) C-terminal truncate PGDH-259 (last 7 residues deleted), prostaglandin E2 methyl ester |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)C-terminal truncate PGDH-263 (last 3 residues deleted) | Homo sapiens | NAD+ | — | 0.0507 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) C-terminal truncate PGDH-263 (last 3 residues deleted), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)C-terminal truncate PGDH-263 (last 3 residues deleted) | Homo sapiens | prostaglandin E2 | — | 0.0031 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) C-terminal truncate PGDH-263 (last 3 residues deleted), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)C-terminal truncate PGDH-263 (last 3 residues deleted) | Homo sapiens | prostaglandin E2 methyl ester | — | 0.0067 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) C-terminal truncate PGDH-263 (last 3 residues deleted), prostaglandin E2 methyl ester |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)human/rat chimera (C-terminal 14 residues from rat 15-PGDH) | Homo sapiens | NAD+ | — | 0.0465 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) human/rat chimera (C-terminal 14 residues from rat 15-PGDH), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)human/rat chimera (C-terminal 14 residues from rat 15-PGDH) | Homo sapiens | prostaglandin E2 | — | 0.0075 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) human/rat chimera (C-terminal 14 residues from rat 15-PGDH), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17A | Homo sapiens | NAD+ | 129 | 0.555 | 200 | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant I17A, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17A | Homo sapiens | prostaglandin E2 | 127 | 0.011 | 1.2 × 10⁴ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant I17A, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17L | Homo sapiens | NAD+ | 165 | 0.059 | 2.8 × 10³ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant I17L, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17L | Homo sapiens | prostaglandin E2 | 210 | 0.0118 | 1.8 × 10⁴ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant I17L, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17V | Homo sapiens | NAD+ | 110 | 0.098 | 1.1 × 10³ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant I17V, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17V | Homo sapiens | prostaglandin E2 | 143 | 0.0112 | 1.3 × 10⁴ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant I17V, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant N91A | Homo sapiens | NAD+ | 91 | 0.719 | 100 | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant N91A, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant N91A | Homo sapiens | prostaglandin E2 | 73 | 0.0061 | 1.2 × 10⁴ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant N91A, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant N91D | Homo sapiens | NAD+ | 42 | 0.032 | 1.3 × 10³ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant N91D, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant N91D | Homo sapiens | prostaglandin E2 | 45 | 0.0026 | 1.7 × 10⁴ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant N91D, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186A | Homo sapiens | NAD+ | 70 | 0.024 | 2.9 × 10³ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant V186A, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186A | Homo sapiens | prostaglandin E2 | 78 | 0.0045 | 1.7 × 10⁴ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant V186A, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186I | Homo sapiens | NAD+ | 247 | 0.272 | 900 | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant V186I, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186I | Homo sapiens | prostaglandin E2 | 262 | 0.0218 | 1.2 × 10⁴ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant V186I, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186K | Homo sapiens | NAD+ | 35 | 0.022 | 1.6 × 10³ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant V186K, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186K | Homo sapiens | prostaglandin E2 | 37 | 0.0035 | 1.1 × 10⁴ | pH 7.5, 37 °C | PMID 15581601 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) variant V186K, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Mus musculus | NAD+ | — | 0.0417 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Mus musculus | prostaglandin E2 | — | 0.008 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Rattus norvegicus | NAD+ | — | 0.0635 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Rattus norvegicus | NAD+pTYB1 intein fusion expressed in E. coli ER2566 | — | 0.0582 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Rattus norvegicus | prostaglandin E2 | — | 0.0099 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | Rattus norvegicus | prostaglandin E2pTYB1 intein fusion expressed in E. coli ER2566 | — | 0.0092 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)rat/human chimera (C-terminal 14 residues from human 15-PGDH) | Rattus norvegicus | NAD+ | — | 0.0484 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) rat/human chimera (C-terminal 14 residues from human 15-PGDH), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)rat/human chimera (C-terminal 14 residues from human 15-PGDH) | Rattus norvegicus | prostaglandin E2 | — | 0.0069 | — | pH 7.5, 37 °C | PMID 11422365 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) rat/human chimera (C-terminal 14 residues from human 15-PGDH), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) | Homo sapiens | NAD+ | — | 0.0315 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I), NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) | Homo sapiens | prostaglandin E2 | — | 0.0063 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I), prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant A14S/Q15K/D36S/W37R | Homo sapiens | NADP+ | — | 0.0279 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant A14S/Q15K/D36S/W37R, NADP+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant A14S/Q15K/D36S/W37R | Homo sapiens | prostaglandin E2 | — | 0.0031 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant A14S/Q15K/D36S/W37R, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K | Homo sapiens | NAD+ | — | 0.0794 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K | Homo sapiens | prostaglandin E2 | — | 0.0267 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/D36A/W37R | Homo sapiens | NADP+ | — | 0.4587 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/D36A/W37R, NADP+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/D36A/W37R | Homo sapiens | prostaglandin E2 | — | 0.1031 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/D36A/W37R, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/D36S/W37R | Homo sapiens | NADP+ | — | 0.4254 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/D36S/W37R, NADP+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/D36S/W37R | Homo sapiens | prostaglandin E2 | — | 0.1068 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/D36S/W37R, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37K | Homo sapiens | NAD+ | — | 0.037 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/W37K, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37K | Homo sapiens | prostaglandin E2 | — | 0.0131 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/W37K, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37R | Homo sapiens | NAD+ | — | 0.074 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/W37R, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37R | Homo sapiens | NADP+ | — | 0.9145 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/W37R, NADP+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37R | Homo sapiens | prostaglandin E2cosubstrate NAD+ | — | 0.0077 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/W37R, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15K/W37R | Homo sapiens | prostaglandin E2cosubstrate NADP+ | — | 0.0461 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15K/W37R, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R | Homo sapiens | NAD+ | — | 0.0321 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15R, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R | Homo sapiens | prostaglandin E2 | — | 0.0053 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15R, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37K | Homo sapiens | NAD+ | — | 0.048 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15R/W37K, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37K | Homo sapiens | prostaglandin E2 | — | 0.0078 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15R/W37K, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37R | Homo sapiens | NAD+ | — | 0.0401 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15R/W37R, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37R | Homo sapiens | NADP+ | — | 0.8922 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15R/W37R, NADP+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37R | Homo sapiens | prostaglandin E2cosubstrate NAD+ | — | 0.0064 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15R/W37R, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant Q15R/W37R | Homo sapiens | prostaglandin E2cosubstrate NADP+ | — | 0.0273 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant Q15R/W37R, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant W37K | Homo sapiens | NAD+ | — | 0.0482 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant W37K, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant W37K | Homo sapiens | prostaglandin E2 | — | 0.0081 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant W37K, prostaglandin E2 |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant W37R | Homo sapiens | NAD+ | — | 0.0289 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant W37R, NAD+ |
| NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I)variant W37R | Homo sapiens | prostaglandin E2 | — | 0.0064 | — | pH 7.5, 37 °C | PMID 14592457 | Open record: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) variant W37R, prostaglandin E2 |