CatLogenzyme kinetics catalog

Values CatLog read from this paper

Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2

PMID 16828555doi:10.1016/j.bmc.2006.06.030Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 7 records (19 values) from this paper: 15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.141

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)Homo sapiensnicotinamide adenine dinucleotide (oxidized, NAD+)——1.24 × 10³pH 7.5, 37 °COpen
15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148EHomo sapiensnicotinamide adenine dinucleotide (oxidized, NAD+)1123.27330pH 7.5, 37 °COpen
15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148EHomo sapiensprostaglandin E21250.02585 × 10³pH 7.5, 37 °COpen
15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148HHomo sapiensnicotinamide adenine dinucleotide (oxidized, NAD+)2660.342780pH 7.5, 37 °COpen
15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148HHomo sapiensprostaglandin E23290.05846 × 10³pH 7.5, 37 °COpen
15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148NHomo sapiensnicotinamide adenine dinucleotide (oxidized, NAD+)2990.241.25 × 10³pH 7.5, 37 °COpen
15-hydroxyprostaglandin dehydrogenase (15-PGDH, Type I, NAD+-dependent)variant Q148NHomo sapiensprostaglandin E22970.02451.2 × 10⁴pH 7.5, 37 °COpen