CatLogenzyme kinetics catalog

Values CatLog read from this paper

Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase

PMID 15581601doi:10.1016/j.abb.2004.09.036Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 18 records (54 values) from this paper: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.141

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)Homo sapiensNAD+470.0381.2 × 10³pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)Homo sapiensprostaglandin E2500.00341.5 × 10⁴pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17AHomo sapiensNAD+1290.555200pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17AHomo sapiensprostaglandin E21270.0111.2 × 10⁴pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17LHomo sapiensNAD+1650.0592.8 × 10³pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17LHomo sapiensprostaglandin E22100.01181.8 × 10⁴pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17VHomo sapiensNAD+1100.0981.1 × 10³pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant I17VHomo sapiensprostaglandin E21430.01121.3 × 10⁴pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant N91AHomo sapiensNAD+910.719100pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant N91AHomo sapiensprostaglandin E2730.00611.2 × 10⁴pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant N91DHomo sapiensNAD+420.0321.3 × 10³pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant N91DHomo sapiensprostaglandin E2450.00261.7 × 10⁴pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186AHomo sapiensNAD+700.0242.9 × 10³pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186AHomo sapiensprostaglandin E2780.00451.7 × 10⁴pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186IHomo sapiensNAD+2470.272900pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186IHomo sapiensprostaglandin E22620.02181.2 × 10⁴pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186KHomo sapiensNAD+350.0221.6 × 10³pH 7.5, 37 °COpen
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)variant V186KHomo sapiensprostaglandin E2370.00351.1 × 10⁴pH 7.5, 37 °COpen