Values CatLog read from this paper
Molecular cloning of a novel type of rat cytoplasmic 17beta-hydroxysteroid dehydrogenase distinct from the type 5 isozyme
PMID 16788056doi:10.1093/jb/mvj109Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 96 records (247 values) from this paper: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) from Rattus norvegicus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 5 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | (S)-indan-1-ol | 0.113 | 3.08 | 0.033 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), (S)-indan-1-ol |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 16-Ketoestrone | 0.087 | 7 × 10⁻⁴ | 125 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 16-Ketoestrone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 17α-Hydroxyprogesterone | 0.103 | 0.05 | 2 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 17α-Hydroxyprogesterone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 17β-Estradiol | 0.42 | 0.014 | 30 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 17β-Estradiol |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 2,3-Butanedione | 0.27 | 0.126 | 2.2 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 2,3-Butanedione |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 2,3-Pentanedione | 0.147 | 0.057 | 2.5 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 2,3-Pentanedione |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 2-Cyclohexen-1-ol | 0.058 | 7 | 0.0083 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 2-Cyclohexen-1-ol |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 21-Dehydrocortisol | 0.12 | 0.0028 | 43 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 21-Dehydrocortisol |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 4-Androsten-3α-ol-17-one | 0.032 | 0.0085 | 3.7 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Androsten-3α-ol-17-one |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 4-Androstene-3,17-dione | 0.033 | 0.0016 | 22 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Androstene-3,17-dione |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 4-Chlorobenzaldehyde | 0.108 | 0.263 | 0.33 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Chlorobenzaldehyde |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 4-Nitroacetophenone | 0.138 | 0.084 | 1.7 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Nitroacetophenone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 4-Nitrobenzaldehyde | 0.132 | 0.011 | 12 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Nitrobenzaldehyde |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 4-pregnen-20alpha-ol-3-one | 0.142 | 0.024 | 5.8 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-pregnen-20alpha-ol-3-one |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 5α-Androstane-3,17-dione | 0.042 | 0.0024 | 18 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5α-Androstane-3,17-dione |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 5α-Androstane-3α,17β-diol | 0.14 | 0.019 | 7.3 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5α-Androstane-3α,17β-diol |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 5α-Dihydrotestosterone | 0.3 | 0.028 | 10.8 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5α-Dihydrotestosterone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 5β-Androstan-17β-ol-3-one | 0.37 | 0.031 | 11.8 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5β-Androstan-17β-ol-3-one |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 5β-Androstane-3,17-dione | 0.027 | 0.0062 | 4.2 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5β-Androstane-3,17-dione |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 5β-Androstane-3α,17β-diol | 0.13 | 0.01 | 13 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5β-Androstane-3α,17β-diol |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione | 0.153 | 0.016 | 9.7 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 9,10-Phenanthrenequinone | 0.3 | 5 × 10⁻⁴ | 600 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 9,10-Phenanthrenequinone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | 9alpha,11beta-prostaglandin F2 | 0.03 | 0.161 | 0.17 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 9alpha,11beta-prostaglandin F2 |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | Acetylpyridine | 0.075 | 0.266 | 0.33 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Acetylpyridine |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | Dehydroepiandrosterone | 0.083 | 0.011 | 7.5 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Dehydroepiandrosterone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | Estrone | 0.045 | 0.011 | 4.2 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Estrone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | Isatin | 0.18 | 0.0021 | 87 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Isatin |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | NAD+ | — | 0.261 | 4.2 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), NAD+ |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | NADH | — | 0.026 | 63 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), NADH |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | NADP+ | — | 0.0015 | 250 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), NADP+ |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | NADPH | — | 5 × 10⁻⁴ | 430 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), NADPH |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | prostaglandin F2alpha (9alpha,11alpha-PGF2) | 0.0085 | 0.054 | 0.17 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), prostaglandin F2alpha (9alpha,11alpha-PGF2) |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | R-CamphorquinoneNADPH as coenzyme at saturating concentration | 0.18 | 0.0016 | 115 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), R-Camphorquinone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | R-Camphorquinonewith 0.1 mM NADPH (reduction direction); cosubstrate NADPH | — | 0.0019 | — | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), R-Camphorquinone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | R-Camphorquinonewith 0.1 mM NADH (reduction direction); cosubstrate NADH | — | 0.019 | — | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), R-Camphorquinone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | S-Camphorquinone | 0.2 | 0.0057 | 35 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), S-Camphorquinone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | Testosterone | 0.35 | 0.021 | 17 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Testosterone |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | trans-1,2-dihydrobenzene-1,2-diol | 0.068 | 2.3 | 0.033 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), trans-1,2-dihydrobenzene-1,2-diol |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | α-3-Hydroxyhexobarbital | 0.038 | 1.1 | 0.033 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), α-3-Hydroxyhexobarbital |
| rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD) | Rattus norvegicus | β-3-Hydroxyhexobarbital | 0.058 | 0.84 | 0.067 | pH 7.4, 25 °C | Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), β-3-Hydroxyhexobarbital |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | 6-tert-butyl-2,3-epoxy-4(S)-hydroxy-5-cyclohexen-1-one | 0.102 | 3.6 | 0.028 calc. | pH 7.4, 25 °C | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), 6-tert-butyl-2,3-epoxy-4(S)-hydroxy-5-cyclohexen-1-one |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione | 0.4 | 0.023 | 17 calc. | pH 7.4, 25 °C | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | trans-1,2-dihydrobenzene-1,2-diol | 0.06 | 0.37 | 0.16 calc. | pH 7.4, 25 °C | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), trans-1,2-dihydrobenzene-1,2-diol |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | α-3-Hydroxyhexobarbital | 0.05 | 1.6 | 0.031 calc. | pH 7.4, 25 °C | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), α-3-Hydroxyhexobarbital |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | β-3-Hydroxyhexobarbital | 0.078 | 2.5 | 0.031 calc. | pH 7.4, 25 °C | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), β-3-Hydroxyhexobarbital |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | (S)-(+)-1,2,3,4-tetrahydro-1-naphtholNAD+ as coenzyme at saturating concentration | 0.75 | 0.168 | 4.5 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), (S)-(+)-1,2,3,4-tetrahydro-1-naphthol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | (S)-(+)-1,2,3,4-tetrahydro-1-naphtholNADP+ as coenzyme; cosubstrate NADP+ | — | 0.53 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), (S)-(+)-1,2,3,4-tetrahydro-1-naphthol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | (S)-(+)-1,2,3,4-tetrahydro-1-naphtholNAD+ as coenzyme (preferred coenzyme NAD(H)) | — | 0.102 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), (S)-(+)-1,2,3,4-tetrahydro-1-naphthol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | (S)-indan-1-ol | 0.42 | 0.134 | 3.2 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), (S)-indan-1-ol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 16-Ketoestrone | 1.88 | 4 × 10⁻⁴ | 4.72 × 10³ | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 16-Ketoestrone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 17α-Hydroxyprogesterone | 0.042 | 0.0025 | 17 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 17α-Hydroxyprogesterone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 17β-EstradiolNAD+ as coenzyme at saturating concentration | 0.15 | 0.033 | 4.5 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 17β-Estradiol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 17β-EstradiolNAD+ as coenzyme (preferred coenzyme NAD(H)) | — | 0.034 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 17β-Estradiol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 2,3-Butanedione | 1.7 | 4.8 | 0.33 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 2,3-Butanedione |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 2,3-Pentanedione | 0.48 | 0.385 | 1.3 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 2,3-Pentanedione |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 2-Cyclohexen-1-olNAD+ as coenzyme at saturating concentration | 0.43 | 1.5 | 0.33 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 2-Cyclohexen-1-ol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 2-Cyclohexen-1-olNAD+ as coenzyme (preferred coenzyme NAD(H)) | — | 1.13 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 2-Cyclohexen-1-ol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 21-Dehydrocortisol | 0.38 | 0.0045 | 85 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 21-Dehydrocortisol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-Androsten-3α-ol-17-oneNAD+ as coenzyme at saturating concentration | 0.06 | 0.014 | 4.2 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-Androsten-3α-ol-17-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-Androsten-3α-ol-17-oneNADH as coenzyme at saturating concentration | 0.022 | 0.013 | 1.7 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-Androsten-3α-ol-17-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-Androsten-3α-ol-17-oneNAD(H) as coenzyme (direction not stated) | — | 0.017 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-Androsten-3α-ol-17-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-Androstene-3,17-dione | 0.017 | 0.017 | 1 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-Androstene-3,17-dione |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-ChlorobenzaldehydeNADH as coenzyme at saturating concentration | 0.22 | 0.028 | 7.7 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-Chlorobenzaldehyde |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-Chlorobenzaldehyde | — | 0.11 | — | pH 6, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-Chlorobenzaldehyde |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-ChlorobenzaldehydeNADPH as coenzyme; cosubstrate NADPH | — | 0.12 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-Chlorobenzaldehyde |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-Nitrobenzaldehyde | 0.3 | 0.096 | 3.3 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-Nitrobenzaldehyde |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-pregnen-20alpha-ol-3-one | 0.053 | 0.0081 | 6.5 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-pregnen-20alpha-ol-3-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-pregnene-17alpha,20alpha-diol-3-oneNAD+ as coenzyme at saturating concentration | 0.132 | 0.012 | 11 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-pregnene-17alpha,20alpha-diol-3-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 4-pregnene-17alpha,20alpha-diol-3-oneNAD+ as coenzyme (preferred coenzyme NAD(H)) | — | 0.014 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 4-pregnene-17alpha,20alpha-diol-3-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5α-Androstane-3,17-dione | 0.022 | 0.018 | 1.2 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5α-Androstane-3,17-dione |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5α-Androstane-3α,17β-diol | 0.07 | 0.017 | 4.2 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5α-Androstane-3α,17β-diol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5α-DihydrotestosteroneNAD+ as coenzyme at saturating concentration | 0.2 | 0.0091 | 21.7 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5α-Dihydrotestosterone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5α-DihydrotestosteroneNAD+ as coenzyme (preferred coenzyme NAD(H)) | — | 0.01 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5α-Dihydrotestosterone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5α-Pregnan-20α-ol-3-one | 0.04 | 0.0051 | 7.8 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5α-Pregnan-20α-ol-3-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5β-Androstan-17β-ol-3-one | 0.23 | 0.0091 | 20 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5β-Androstan-17β-ol-3-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5β-Androstane-3,17-dione | 0.053 | 0.019 | 2.8 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5β-Androstane-3,17-dione |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5β-Androstane-3α,17β-diol | 0.47 | 0.0035 | 135 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5β-Androstane-3α,17β-diol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5β-Pregnan-20α-ol-3-one | 0.017 | 0.019 | 0.83 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5β-Pregnan-20α-ol-3-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5β-Pregnan-3α-ol-20-one | 0.0138 | 0.0084 | 1.7 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5β-Pregnan-3α-ol-20-one |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 5β-Pregnane-3,20-dione | 0.013 | 0.0016 | 8.2 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 5β-Pregnane-3,20-dione |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione | 1.25 | 0.18 | 7 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione | — | 0.3 | — | pH 6, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 9,10-Phenanthrenequinone | 2.62 | 4 × 10⁻⁴ | 6.55 × 10³ | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 9,10-Phenanthrenequinone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | 9alpha,11beta-prostaglandin F2 | 0.0025 | 0.024 | 0.1 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), 9alpha,11beta-prostaglandin F2 |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | IsatinNADH as coenzyme at saturating concentration | 1.75 | 0.0022 | 800 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), Isatin |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | IsatinNADH as coenzyme (preferred coenzyme NAD(H)) | — | 0.002 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), Isatin |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | prostaglandin F2alpha (9alpha,11alpha-PGF2) | 0.0028 | 0.072 | 0.033 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), prostaglandin F2alpha (9alpha,11alpha-PGF2) |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | R-Camphorquinone | 1.3 | 0.033 | 40 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), R-Camphorquinone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | S-CamphorquinoneNADH as coenzyme at saturating concentration | 1.88 | 0.0099 | 180 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), S-Camphorquinone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | S-CamphorquinoneNADH as coenzyme (preferred coenzyme NAD(H)) | — | 0.01 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), S-Camphorquinone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | TestosteroneNAD+ as coenzyme at saturating concentration | 0.27 | 0.025 | 10.3 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), Testosterone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | TestosteroneNAD+ as coenzyme (preferred coenzyme NAD(H)) | — | 0.027 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), Testosterone |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | trans-1,2-dihydrobenzene-1,2-diolNAD+ as coenzyme at saturating concentration | 0.63 | 0.215 | 3 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), trans-1,2-dihydrobenzene-1,2-diol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | trans-1,2-dihydrobenzene-1,2-diolNAD+ as coenzyme (preferred coenzyme NAD(H)) | — | 0.215 | — | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), trans-1,2-dihydrobenzene-1,2-diol |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | α-3-Hydroxyhexobarbital | 0.28 | 0.42 | 0.67 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), α-3-Hydroxyhexobarbital |
| TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24) | Rattus norvegicus | β-3-Hydroxyhexobarbital | 0.12 | 1.18 | 0.1 | pH 7.4, 25 °C | Open record: TBER1 (6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione reductase 1; NAD+-dependent 17beta-HSD, AKR1C24), β-3-Hydroxyhexobarbital |