EC 1.1.1.64: testosterone 17beta-dehydrogenase (NADP+)

OxidoreductasesOpen in Browse

CatLog read 100 records for EC 1.1.1.64 from 8 papers, for 2 organisms. Names in these papers: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), aldo-keto reductase 1B15 (AKR1B15.1), AKR1C3, 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 25 records for EC 1.1.1.64 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.64 in Browse.

Papers

Papers with records for EC 1.1.1.64
Paper	Organisms	Records
Molecular cloning of a novel type of rat cytoplasmic 17beta-hydroxysteroid dehydrogenase distinct from the type 5 isozyme	Rattus norvegicus	40
Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase	Homo sapiens	21
Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone	Homo sapiens	15
Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes	Homo sapiens	12
Aldo-keto Reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates	Homo sapiens	7
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target…	Homo sapiens	2
A new branch of mammalian vitamin B₆ metabolism: AKR1C-mediated conversion of pyridoxal to pyridoxine and 4-pyridoxolactone	Homo sapiens	2
Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone…	Homo sapiens	1

Records

Records for EC 1.1.1.64 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-17β-ol-3-oneno SSRI added	—	0.00237	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-17β-ol-3-one	—	5 × 10⁻⁵	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-17β-ol-3-one	—	3.9 × 10⁻⁴	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-17β-ol-3-one	—	0.0178	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-3α,17β-diolno SSRI added	—	0.001	—	pH 8.9	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-3α,17β-diol	—	0.0072	—	pH 8.9	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-3α,17β-diol	—	4.6 × 10⁻⁴	—	pH 8.9	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-3α,17β-diol	—	2.1 × 10⁻⁴	—	pH 8.9	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	progesteroneno SSRI added	—	0.1421	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	progesterone	—	0.238	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	progesterone	—	0.121	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	progesterone	—	0.1499	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone
AKR1B15.1	Homo sapiens	17β-Estradiol	0.0083	0.0091	1	pH 7.4, 37 °C	PMID 25577493	Open record: AKR1B15.1, 17β-Estradiol
AKR1B15.1	Homo sapiens	3α,17β-Androstandiol	0.05	0.0192	2.7	pH 7.4, 37 °C	PMID 25577493	Open record: AKR1B15.1, 3α,17β-Androstandiol
AKR1B15.1	Homo sapiens	Acetoacetyl-CoA	0.0083	0.0634	0.17	pH 7, 37 °C	PMID 25577493	Open record: AKR1B15.1, Acetoacetyl-CoA
AKR1B15.1	Homo sapiens	androst-4-ene-3,17-dione	0.018	0.0019	10	pH 7.4, 37 °C	PMID 25577493	Open record: AKR1B15.1, androst-4-ene-3,17-dione
AKR1B15.1	Homo sapiens	Androsterone	0.028	0.0028	10.2	pH 7.4, 37 °C	PMID 25577493	Open record: AKR1B15.1, Androsterone
AKR1B15.1	Homo sapiens	Estrone	0.017	0.0025	6.3	pH 7.4, 37 °C	PMID 25577493	Open record: AKR1B15.1, Estrone
AKR1B15.1	Homo sapiens	Testosterone	0.01	0.0071	1.5	pH 7.4, 37 °C	PMID 25577493	Open record: AKR1B15.1, Testosterone
AKR1C3	Homo sapiens	(S)-1,2,3,4-tetrahydro-1-naphthol	0.58	1.4	0.5	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, (S)-1,2,3,4-tetrahydro-1-naphthol
AKR1C3	Homo sapiens	17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)	0.0038	—	—	pH 7, 37 °C	PMID 14672942	Open record: AKR1C3, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)
AKR1C3	Homo sapiens	4-pregnen-20α-ol-3-one	5 × 10⁻⁴	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 4-pregnen-20α-ol-3-one
AKR1C3	Homo sapiens	5α-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.0087	0.0021	4.2	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnan-20α-ol-3-one
AKR1C3	Homo sapiens	5α-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	1.7 × 10⁻⁴	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnan-20α-ol-3-one
AKR1C3	Homo sapiens	5α-pregnan-3α-ol-20-one	0.0013	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnan-3α-ol-20-one
AKR1C3	Homo sapiens	5α-pregnane-21-ol-3,20-dione	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnane-21-ol-3,20-dione
AKR1C3	Homo sapiens	5α-pregnane-3,20-dione	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnane-3,20-dione
AKR1C3	Homo sapiens	5α-pregnane-3α,20α-diol	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnane-3α,20α-diol
AKR1C3	Homo sapiens	5α-pregnane-3α,21-diol-20-one	1.7 × 10⁻⁴	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnane-3α,21-diol-20-one
AKR1C3	Homo sapiens	5β-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.018	9 × 10⁻⁴	20	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnan-20α-ol-3-one
AKR1C3	Homo sapiens	5β-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	5 × 10⁻⁴	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnan-20α-ol-3-one
AKR1C3	Homo sapiens	5β-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnan-3α-ol-20-one
AKR1C3	Homo sapiens	5β-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnan-3α-ol-20-one
AKR1C3	Homo sapiens	5β-pregnane-3,20-dione	0.0032	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnane-3,20-dione
AKR1C3	Homo sapiens	5β-pregnane-3α,20α-diol	0.028	0.027	1	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnane-3α,20α-diol
AKR1C3	Homo sapiens	9,10-phenanthrenequinone	1.4	0.0015	920	pH 7, 37 °C	PMID 17950253	Open record: AKR1C3, 9,10-phenanthrenequinone
AKR1C3	Homo sapiens	androst-4-ene-3,17-dione	0.0027	0.0066	0.4	pH 7, 37 °C	PMID 17950253	Open record: AKR1C3, androst-4-ene-3,17-dione
AKR1C3	Homo sapiens	pyridoxalpyridoxal reductase (PLR) activity; PL -> pyridoxine	0.0053	0.298	0.018	pH 7, 37 °C	PMID 41741972	Open record: AKR1C3, pyridoxal
AKR1C3	Homo sapiens	pyridoxalpyridoxal dehydrogenase (PLD) activity; 0.2 mM NADP+	0.0127	1.02	0.013	pH 7, 37 °C	PMID 41741972	Open record: AKR1C3, pyridoxal
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	2,3-butanedione	0.177	—	—	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 2,3-butanedione
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	2,3-hexanedione	0.158	—	—	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 2,3-hexanedione
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	2,4-pentanedione	0.037	0.04	0.92	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 2,4-pentanedione
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	2-butanone	0.175	0.78	0.225	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 2-butanone
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	2-cyclohexen-1-one	0.0735	0.365	0.202	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 2-cyclohexen-1-one
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	3,5-heptanedione	0.088	1.3	0.065	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 3,5-heptanedione
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	3-buten-2-one	0.137	0.0213	6.3	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 3-buten-2-one
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	3-nonen-2-one	0.1127	0.0017	67	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 3-nonen-2-one
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	4-hydroxy-2-nonenal	0.087	0.0022	42	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 4-hydroxy-2-nonenal
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	9-cis-retinaldehyde	0.063	1.6 × 10⁻⁴	427	pH 7.4, 37 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), 9-cis-retinaldehyde
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	acrolein	0.147	0.036	4	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), acrolein
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	all-trans-retinaldehyde	0.09	0.001	88	pH 7.4, 37 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), all-trans-retinaldehyde
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	benzaldehyde	0.202	—	—	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), benzaldehyde
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	cinnamaldehyde	0.222	—	—	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), cinnamaldehyde
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	citral	0.092	0.0015	62	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), citral
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	d,l-glyceraldehyde	0.178	0.88	0.207	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), d,l-glyceraldehyde
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	farnesal	0.08	—	—	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), farnesal
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	hexanal	0.122	0.0031	38	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), hexanal
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	NADPH	—	0.0057	—	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), NADPH
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	pyridine-3-aldehyde	0.15	0.0029	52.5	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), pyridine-3-aldehyde
aldo-keto reductase 1B15 (AKR1B15.1)	Homo sapiens	trans-2-hexenal	0.188	0.005	37	pH 7, 25 °C	PMID 26222439	Open record: aldo-keto reductase 1B15 (AKR1B15.1), trans-2-hexenal
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	(S)-indan-1-ol	0.113	3.08	0.033	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), (S)-indan-1-ol
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	16-Ketoestrone	0.087	7 × 10⁻⁴	125	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 16-Ketoestrone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	17α-Hydroxyprogesterone	0.103	0.05	2	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 17α-Hydroxyprogesterone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	17β-Estradiol	0.42	0.014	30	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 17β-Estradiol
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	2,3-Butanedione	0.27	0.126	2.2	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 2,3-Butanedione
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	2,3-Pentanedione	0.147	0.057	2.5	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 2,3-Pentanedione
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	2-Cyclohexen-1-ol	0.058	7	0.0083	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 2-Cyclohexen-1-ol
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	21-Dehydrocortisol	0.12	0.0028	43	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 21-Dehydrocortisol
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	4-Androsten-3α-ol-17-one	0.032	0.0085	3.7	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Androsten-3α-ol-17-one
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	4-Androstene-3,17-dione	0.033	0.0016	22	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Androstene-3,17-dione
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	4-Chlorobenzaldehyde	0.108	0.263	0.33	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Chlorobenzaldehyde
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	4-Nitroacetophenone	0.138	0.084	1.7	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Nitroacetophenone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	4-Nitrobenzaldehyde	0.132	0.011	12	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-Nitrobenzaldehyde
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	4-pregnen-20alpha-ol-3-one	0.142	0.024	5.8	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 4-pregnen-20alpha-ol-3-one
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	5α-Androstane-3,17-dione	0.042	0.0024	18	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5α-Androstane-3,17-dione
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	5α-Androstane-3α,17β-diol	0.14	0.019	7.3	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5α-Androstane-3α,17β-diol
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	5α-Dihydrotestosterone	0.3	0.028	10.8	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5α-Dihydrotestosterone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	5β-Androstan-17β-ol-3-one	0.37	0.031	11.8	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5β-Androstan-17β-ol-3-one
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	5β-Androstane-3,17-dione	0.027	0.0062	4.2	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5β-Androstane-3,17-dione
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	5β-Androstane-3α,17β-diol	0.13	0.01	13	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 5β-Androstane-3α,17β-diol
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione	0.153	0.016	9.7	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	9,10-Phenanthrenequinone	0.3	5 × 10⁻⁴	600	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 9,10-Phenanthrenequinone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	9alpha,11beta-prostaglandin F2	0.03	0.161	0.17	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), 9alpha,11beta-prostaglandin F2
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	Acetylpyridine	0.075	0.266	0.33	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Acetylpyridine
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	Dehydroepiandrosterone	0.083	0.011	7.5	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Dehydroepiandrosterone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	Estrone	0.045	0.011	4.2	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Estrone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	Isatin	0.18	0.0021	87	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Isatin
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	NAD+	—	0.261	4.2	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), NAD+
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	NADH	—	0.026	63	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), NADH
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	NADP+	—	0.0015	250	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), NADP+
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	NADPH	—	5 × 10⁻⁴	430	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), NADPH
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	prostaglandin F2alpha (9alpha,11alpha-PGF2)	0.0085	0.054	0.17	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), prostaglandin F2alpha (9alpha,11alpha-PGF2)
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	R-CamphorquinoneNADPH as coenzyme at saturating concentration	0.18	0.0016	115	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), R-Camphorquinone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	R-Camphorquinonewith 0.1 mM NADPH (reduction direction); cosubstrate NADPH	—	0.0019	—	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), R-Camphorquinone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	R-Camphorquinonewith 0.1 mM NADH (reduction direction); cosubstrate NADH	—	0.019	—	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), R-Camphorquinone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	S-Camphorquinone	0.2	0.0057	35	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), S-Camphorquinone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	Testosterone	0.35	0.021	17	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), Testosterone
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	trans-1,2-dihydrobenzene-1,2-diol	0.068	2.3	0.033	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), trans-1,2-dihydrobenzene-1,2-diol
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	α-3-Hydroxyhexobarbital	0.038	1.1	0.033	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), α-3-Hydroxyhexobarbital
rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD)	Rattus norvegicus	β-3-Hydroxyhexobarbital	0.058	0.84	0.067	pH 7.4, 25 °C	PMID 16788056	Open record: rat 17beta-hydroxysteroid dehydrogenase type 5 (17HSD5, rHSD), β-3-Hydroxyhexobarbital