CatLogenzyme kinetics catalog

Values CatLog read from this paper

A new branch of mammalian vitamin B6 metabolism: AKR1C-mediated conversion of pyridoxal to pyridoxine and 4-pyridoxolactone

PMID 41741972doi:10.1111/febs.70471Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 7 records (17 values) from this paper: AKR1C1, AKR1C3, AKR1C6 and 1 more from Homo sapiens, Mus musculus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.51, EC 1.1.1.53, EC 1.1.1.62, EC 1.1.1.64, EC 1.1.1.112, EC 1.1.1.149, EC 1.1.1.188, EC 1.1.1.209, EC 1.1.1.210, EC 1.1.1.225, EC 1.1.1.239, EC 1.1.1.270, EC 1.1.1.357, EC 1.3.1.20

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
AKR1C1Homo sapienspyridoxalpyridoxal reductase (PLR) activity; PL -> pyridoxine0.0420.3630.115pH 7, 37 °COpen
AKR1C1Homo sapienspyridoxalpyridoxal dehydrogenase (PLD) activity; 0.2 mM NADP+0.0570.6290.09pH 7, 37 °COpen
AKR1C3Homo sapienspyridoxalpyridoxal reductase (PLR) activity; PL -> pyridoxine0.00530.2980.018pH 7, 37 °COpen
AKR1C3Homo sapienspyridoxalpyridoxal dehydrogenase (PLD) activity; 0.2 mM NADP+0.01271.020.013pH 7, 37 °COpen
AKR1C4Homo sapienspyridoxal0.0060.3040.02pH 7, 37 °COpen
AKR1C6Mus musculuspyridoxalpyridoxal reductase (PLR) activity; PL -> pyridoxine——0.17pH 7, 37 °COpen
AKR1C6Mus musculuspyridoxalpyridoxal dehydrogenase (PLD) activity; 0.2 mM NADP+——0.027pH 7, 37 °COpen