EC 1.1.1.239: 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)

OxidoreductasesOpen in Browse

CatLog read 136 records for EC 1.1.1.239 from 12 papers, for 4 organisms. Names in these papers: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), AKR1C3, 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) and 7 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 57 records for EC 1.1.1.239 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.239 in Browse.

Papers

Papers with records for EC 1.1.1.239
Paper	Organisms	Records
Characterization of rabbit morphine 6-dehydrogenase and two NAD(+)-dependent 3α(17β)-hydroxysteroid dehydrogenases	Oryctolagus cuniculus	68
Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone	Homo sapiens	15
Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes	Homo sapiens	12
Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate	Homo sapiens, Rattus norvegicus	11
Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization…	Homo sapiens	9
Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity	Homo sapiens	6
Molecular characterization of a first human 3(alpha-->beta)-hydroxysteroid epimerase	Homo sapiens	5
Characterization of Ke 6, a new 17beta-hydroxysteroid dehydrogenase, and its expression in gonadal tissues	Mus musculus	4
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target…	Homo sapiens	2
A new branch of mammalian vitamin B₆ metabolism: AKR1C-mediated conversion of pyridoxal to pyridoxine and 4-pyridoxolactone	Homo sapiens	2
Complementary deoxyribonucleic acid cloning and enzymatic characterization of a novel 17beta/3alpha-hydroxysteroid/retinoid short chain dehydrogenase/reductase	Mus musculus	1
Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone…	Homo sapiens	1

Records

Records for EC 1.1.1.239 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
17beta/3alpha-hydroxysteroid/retinoid short chain dehydrogenase/reductase (17bHSD9)	Mus musculus	all-trans-retinol	—	0.0032	—	pH 9, 37 °C	PMID 10537158	Open record: 17beta/3alpha-hydroxysteroid/retinoid short chain dehydrogenase/reductase (17bHSD9), all-trans-retinol
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)	Rattus norvegicus	4-androsten-17beta-ol-3-one	—	0.0011	—	pH 7.5, 37 °C	PMID 9188497	Open record: 17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6), 4-androsten-17beta-ol-3-one
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)	Rattus norvegicus	5alpha-androstan-17beta-ol-3-one	—	5 × 10⁻⁴	—	pH 7.5, 37 °C	PMID 9188497	Open record: 17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6), 5alpha-androstan-17beta-ol-3-one
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)	Rattus norvegicus	5alpha-androstan-3alpha-ol-17-one	—	2 × 10⁻⁴	—	pH 7.5, 37 °C	PMID 9188497	Open record: 17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6), 5alpha-androstan-3alpha-ol-17-one
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)	Rattus norvegicus	5alpha-androstane-3alpha,17beta-diol	—	1 × 10⁻⁴	—	pH 7.5, 37 °C	PMID 9188497	Open record: 17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6), 5alpha-androstane-3alpha,17beta-diol
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)	Rattus norvegicus	Estradiol	—	8 × 10⁻⁴	—	pH 7.5, 37 °C	PMID 9188497	Open record: 17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6), Estradiol
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)	Rattus norvegicus	NAD+	—	0.003	—	pH 7.5, 37 °C	PMID 9188497	Open record: 17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6), NAD+
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)	Rattus norvegicus	NADP+	—	1	—	pH 7.5, 37 °C	PMID 9188497	Open record: 17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6), NADP+
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)	Homo sapiens	11-dehydrocorticosterone	5 × 10⁻⁴	0.0017	0.3	pH 9.3, 25 °C	PMID 12917011	Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 11-dehydrocorticosterone
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)	Homo sapiens	3-hydroxybutyryl-CoA	4.83	0.0852	57	pH 9.3, 25 °C	PMID 12917011	Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 3-hydroxybutyryl-CoA
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)	Homo sapiens	3α,7α-dihydroxy-5β-cholan-24-oic acid	5.7 × 10⁻⁴	0.0364	0.017	pH 9.3, 25 °C	PMID 12917011	Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 3α,7α-dihydroxy-5β-cholan-24-oic acid
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)	Homo sapiens	3β,7β-dihydroxy-5β-cholan-24-oic acid	9 × 10⁻⁴	0.219	0.0033	pH 9.3, 25 °C	PMID 12917011	Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 3β,7β-dihydroxy-5β-cholan-24-oic acid
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)	Homo sapiens	5α-androstan-3α-ol-17-one	6.7 × 10⁻⁴	0.041	0.017	pH 9.3, 25 °C	PMID 12917011	Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 5α-androstan-3α-ol-17-one
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)	Homo sapiens	5α-pregnan-20β-ol-3-one	0.0042	0.005	0.88	pH 9.3, 25 °C	PMID 12917011	Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 5α-pregnan-20β-ol-3-one
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)	Homo sapiens	acetoacetyl-CoA	23.8	0.0257	927	pH 7, 25 °C	PMID 12917011	Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), acetoacetyl-CoA
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)	Homo sapiens	NAD+	—	0.0423	—	pH 9.3, 25 °C	PMID 12917011	Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), NAD+
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)	Homo sapiens	NADH	—	0.0306	—	pH 7, 25 °C	PMID 12917011	Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), NADH
17β-hydroxysteroid dehydrogenase type 2	Homo sapiens	(17β)-estra-1,3,5(10)-triene-3,17-diol	—	2.1 × 10⁻⁴	—	pH 7.4, 37 °C	PMID 8099587	Open record: 17β-hydroxysteroid dehydrogenase type 2, (17β)-estra-1,3,5(10)-triene-3,17-diol
17β-hydroxysteroid dehydrogenase type 2	Homo sapiens	17β-hydroxy-4-androsten-3-one	—	3.9 × 10⁻⁴	—	pH 7.4, 37 °C	PMID 8099587	Open record: 17β-hydroxysteroid dehydrogenase type 2, 17β-hydroxy-4-androsten-3-one
17β-hydroxysteroid dehydrogenase type 2	Homo sapiens	17β-hydroxy-5α-androstan-3-one	—	3.1 × 10⁻⁴	—	pH 7.4, 37 °C	PMID 8099587	Open record: 17β-hydroxysteroid dehydrogenase type 2, 17β-hydroxy-5α-androstan-3-one
17β-hydroxysteroid dehydrogenase type 2	Homo sapiens	20α-hydroxypregn-4-ene-3-one	—	7.1 × 10⁻⁴	—	pH 7.4, 37 °C	PMID 8099587	Open record: 17β-hydroxysteroid dehydrogenase type 2, 20α-hydroxypregn-4-ene-3-one
17β-hydroxysteroid dehydrogenase type 2	Homo sapiens	3-hydroxyestra-1,3,5(10)-trien-17-one	—	7.8 × 10⁻⁴	—	pH 7.4, 37 °C	PMID 8099587	Open record: 17β-hydroxysteroid dehydrogenase type 2, 3-hydroxyestra-1,3,5(10)-trien-17-one
17β-hydroxysteroid dehydrogenase type 2	Homo sapiens	androst-4-ene-3,17-dione	—	0.00263	—	pH 7.4, 37 °C	PMID 8099587	Open record: 17β-hydroxysteroid dehydrogenase type 2, androst-4-ene-3,17-dione
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)	Homo sapiens	5α-androstane-3,17-dioneproduct: ADT (androsterone)	—	4 × 10⁻⁴	—	pH 7.4, 37 °C	PMID 10896656	Open record: 3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE), 5α-androstane-3,17-dione
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)	Homo sapiens	5α-androstane-3,17-dioneproduct: epi-ADT (epi-androsterone)	—	2 × 10⁻⁴	—	pH 7.4, 37 °C	PMID 10896656	Open record: 3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE), 5α-androstane-3,17-dione
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)	Homo sapiens	5α-androstane-3β-ol-17-one	—	0.0017	—	pH 7.4, 37 °C	PMID 10896656	Open record: 3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE), 5α-androstane-3β-ol-17-one
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)	Homo sapiens	5α-pregnane-3α-ol-20-one	—	0.003	—	pH 7.4, 37 °C	PMID 10896656	Open record: 3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE), 5α-pregnane-3α-ol-20-one
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)	Homo sapiens	androsterone	—	4 × 10⁻⁴	—	pH 7.4, 37 °C	PMID 10896656	Open record: 3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE), androsterone
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-17β-ol-3-oneno SSRI added	—	0.00237	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-17β-ol-3-one	—	5 × 10⁻⁵	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-17β-ol-3-one	—	3.9 × 10⁻⁴	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-17β-ol-3-one	—	0.0178	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-3α,17β-diolno SSRI added	—	0.001	—	pH 8.9	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-3α,17β-diol	—	0.0072	—	pH 8.9	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-3α,17β-diol	—	4.6 × 10⁻⁴	—	pH 8.9	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	5α-androstan-3α,17β-diol	—	2.1 × 10⁻⁴	—	pH 8.9	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	progesteroneno SSRI added	—	0.1421	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	progesterone	—	0.238	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	progesterone	—	0.121	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)	Homo sapiens	progesterone	—	0.1499	—	pH 7.3, 37 °C	PMID 10557352	Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	1-phenyl-1,2-propanedione	0.45	0.005	90	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 1-phenyl-1,2-propanedione
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	16-ketoestrone	0.87	0.01	87	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 16-ketoestrone
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	17β-estradiol	0.0063	0.1	0.067	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 17β-estradiol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	2,3-butanedione	0.55	0.371	1.5	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 2,3-butanedione
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	2-cyclohexen-1-ol	0.105	0.67	0.15	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 2-cyclohexen-1-ol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	4-pregnen-3α-ol-20-one	0.0118	0.081	0.15	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 4-pregnen-3α-ol-20-one
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5α-androstan-17β-ol-3-one	0.0103	0.13	0.083	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-androstan-17β-ol-3-one
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5β-androstan-17β-ol-3-one	0.002	0.03	0.067	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-androstan-17β-ol-3-one
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5β-pregnan-3α-ol-20-one	0.023	0.17	0.13	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-pregnan-3α-ol-20-one
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one	0.108	0.101	1	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	9,10-phenanthrenequinone	0.62	2 × 10⁻⁴	3.08 × 10³	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 9,10-phenanthrenequinone
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	geraniol	0.0153	0.57	0.033	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), geraniol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	isatin	0.65	0.0011	580	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), isatin
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	lithocholic acid	0.018	0.14	0.13	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), lithocholic acid
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	NAD+	0.28	0.012	23	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NAD+
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	NADH	0.68	0.0043	108	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NADH
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	NADP+	0.103	0.068	1.52	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NADP+
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	pyridine-3-aldehyde	0.2	1.1	0.17	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), pyridine-3-aldehyde
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	S-(+)-1,2,3,4-tetrahydro-1-naphthol	0.37	0.25	1.47	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-(+)-1,2,3,4-tetrahydro-1-naphthol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	S-1-indanol	0.4	0.11	3.7	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-1-indanol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	S-camphorquinone	0.98	0.0087	113	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-camphorquinone
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	testosterone	0.0082	0.25	0.033	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), testosterone
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	trans-cyclohexa-3,5-diene-1,2-diol	0.127	1.11	0.12	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), trans-cyclohexa-3,5-diene-1,2-diol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	α-tetralone	0.2	0.15	1.3	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), α-tetralone
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant F310I	Oryctolagus cuniculus	17β-estradiol	0.025	0.029	0.87	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant F310I, 17β-estradiol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant F310I	Oryctolagus cuniculus	5α-androstan-17β-ol-3-one	0.103	0.055	1.8	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant F310I, 5α-androstan-17β-ol-3-one
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant F310I	Oryctolagus cuniculus	S-(+)-1,2,3,4-tetrahydro-1-naphthol	0.147	0.13	1.13	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant F310I, S-(+)-1,2,3,4-tetrahydro-1-naphthol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant F310I	Oryctolagus cuniculus	testosterone	0.105	0.129	0.82	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant F310I, testosterone
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F	Oryctolagus cuniculus	17β-estradiol	0.0128	0.016	0.8	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F, 17β-estradiol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F	Oryctolagus cuniculus	5α-androstan-17β-ol-3-one	0.016	0.04	0.4	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F, 5α-androstan-17β-ol-3-one
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F	Oryctolagus cuniculus	S-(+)-1,2,3,4-tetrahydro-1-naphthol	0.2	0.022	9.2	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F, S-(+)-1,2,3,4-tetrahydro-1-naphthol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F	Oryctolagus cuniculus	testosterone	0.0107	0.088	0.12	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F, testosterone
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F/F310I	Oryctolagus cuniculus	17β-estradiol	0.025	0.0026	9.7	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F/F310I, 17β-estradiol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F/F310I	Oryctolagus cuniculus	5α-androstan-17β-ol-3-one	0.058	0.015	3.8	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F/F310I, 5α-androstan-17β-ol-3-one
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F/F310I	Oryctolagus cuniculus	S-(+)-1,2,3,4-tetrahydro-1-naphthol	0.22	0.005	40	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F/F310I, S-(+)-1,2,3,4-tetrahydro-1-naphthol
AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F/F310I	Oryctolagus cuniculus	testosterone	0.068	0.045	1.52	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F/F310I, testosterone
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	1-phenyl-1,2-propanedione	0.155	8 × 10⁻⁴	200	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 1-phenyl-1,2-propanedione
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	16-ketoestrone	0.27	0.0021	127	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 16-ketoestrone
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	17β-estradiol	0.022	0.0021	10.3	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 17β-estradiol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	2,3-butanedione	0.23	0.19	1.2	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 2,3-butanedione
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	2-cyclohexen-1-ol	0.072	0.066	1.1	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 2-cyclohexen-1-ol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	4-pregnen-20α-ol-3-one	0.0038	0.019	0.2	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 4-pregnen-20α-ol-3-one
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	4-pregnen-3α-ol-20-one	0.0032	0.0073	0.43	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 4-pregnen-3α-ol-20-one
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5α-androstan-17β-ol-3-one	0.065	0.0078	8.7	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-androstan-17β-ol-3-one
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5α-androstan-3α-ol-17-one	0.0033	0.0023	1.48	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-androstan-3α-ol-17-one
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5α-androstane-3α,17β-diol	0.055	0.0078	7.2	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-androstane-3α,17β-diol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5α-pregnan-3α-ol-20-one	0.0072	0.0035	2	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-pregnan-3α-ol-20-one
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5β-androstan-17β-ol-3-one	0.017	0.0076	2.2	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-androstan-17β-ol-3-one
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5β-androstan-3α-ol-17-one	0.0023	0.002	1.2	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-androstan-3α-ol-17-one
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5β-androstane-3α,17β-diol	0.0122	0.0022	5.5	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-androstane-3α,17β-diol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	5β-pregnan-3α-ol-20-one	0.005	0.0036	1.38	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-pregnan-3α-ol-20-one
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one	0.108	0.0021	52	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	9,10-phenanthrenequinone	0.23	1 × 10⁻⁴	230	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 9,10-phenanthrenequinone
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	farnesol	0.027	4 × 10⁻⁴	67	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), farnesol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	geraniol	0.028	0.0042	6.7	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), geraniol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	geranylgeraniol	0.0127	7 × 10⁻⁴	18	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), geranylgeraniol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	isatin	0.18	8 × 10⁻⁴	230	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), isatin
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	NAD+	0.1	0.0096	15.7	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NAD+
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	NADH	0.22	0.0026	83	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NADH
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	NADP+	0.033	0.075	0.45	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NADP+
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	pyridine-3-aldehyde	0.07	0.29	0.17	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), pyridine-3-aldehyde
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	S-(+)-1,2,3,4-tetrahydro-1-naphthol	0.1	0.004	25	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-(+)-1,2,3,4-tetrahydro-1-naphthol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	S-1-indanol	0.13	0.014	9.2	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-1-indanol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	S-camphorquinone	0.18	0.0019	97	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-camphorquinone
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	testosterone	0.098	0.037	2.7	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), testosterone
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	trans-cyclohexa-3,5-diene-1,2-diol	0.088	0.12	0.73	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), trans-cyclohexa-3,5-diene-1,2-diol
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	α-tetralone	0.025	0.06	0.5	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), α-tetralone
AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)	Oryctolagus cuniculus	β-ionol	0.028	6 × 10⁻⁴	47	pH 7.4, 25 °C	PMID 23228597	Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), β-ionol
AKR1C3	Homo sapiens	(S)-1,2,3,4-tetrahydro-1-naphthol	0.58	1.4	0.5	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, (S)-1,2,3,4-tetrahydro-1-naphthol
AKR1C3	Homo sapiens	17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)	0.0038	—	—	pH 7, 37 °C	PMID 14672942	Open record: AKR1C3, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)
AKR1C3	Homo sapiens	4-pregnen-20α-ol-3-one	5 × 10⁻⁴	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 4-pregnen-20α-ol-3-one
AKR1C3	Homo sapiens	5α-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.0087	0.0021	4.2	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnan-20α-ol-3-one
AKR1C3	Homo sapiens	5α-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	1.7 × 10⁻⁴	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnan-20α-ol-3-one
AKR1C3	Homo sapiens	5α-pregnan-3α-ol-20-one	0.0013	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnan-3α-ol-20-one
AKR1C3	Homo sapiens	5α-pregnane-21-ol-3,20-dione	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnane-21-ol-3,20-dione
AKR1C3	Homo sapiens	5α-pregnane-3,20-dione	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnane-3,20-dione
AKR1C3	Homo sapiens	5α-pregnane-3α,20α-diol	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnane-3α,20α-diol
AKR1C3	Homo sapiens	5α-pregnane-3α,21-diol-20-one	1.7 × 10⁻⁴	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5α-pregnane-3α,21-diol-20-one
AKR1C3	Homo sapiens	5β-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.018	9 × 10⁻⁴	20	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnan-20α-ol-3-one
AKR1C3	Homo sapiens	5β-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	5 × 10⁻⁴	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnan-20α-ol-3-one
AKR1C3	Homo sapiens	5β-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnan-3α-ol-20-one
AKR1C3	Homo sapiens	5β-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnan-3α-ol-20-one
AKR1C3	Homo sapiens	5β-pregnane-3,20-dione	0.0032	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnane-3,20-dione
AKR1C3	Homo sapiens	5β-pregnane-3α,20α-diol	0.028	0.027	1	pH 7, 25 °C	PMID 12604236	Open record: AKR1C3, 5β-pregnane-3α,20α-diol
AKR1C3	Homo sapiens	9,10-phenanthrenequinone	1.4	0.0015	920	pH 7, 37 °C	PMID 17950253	Open record: AKR1C3, 9,10-phenanthrenequinone
AKR1C3	Homo sapiens	androst-4-ene-3,17-dione	0.0027	0.0066	0.4	pH 7, 37 °C	PMID 17950253	Open record: AKR1C3, androst-4-ene-3,17-dione
AKR1C3	Homo sapiens	pyridoxalpyridoxal reductase (PLR) activity; PL -> pyridoxine	0.0053	0.298	0.018	pH 7, 37 °C	PMID 41741972	Open record: AKR1C3, pyridoxal
AKR1C3	Homo sapiens	pyridoxalpyridoxal dehydrogenase (PLD) activity; 0.2 mM NADP+	0.0127	1.02	0.013	pH 7, 37 °C	PMID 41741972	Open record: AKR1C3, pyridoxal
Ke 6 (17beta-hydroxysteroid dehydrogenase)	Mus musculus	17beta-estradiol	—	1.1 × 10⁻⁴	—		PMID 9712896	Open record: Ke 6 (17beta-hydroxysteroid dehydrogenase), 17beta-estradiol
Ke 6 (17beta-hydroxysteroid dehydrogenase)	Mus musculus	5alpha-dihydrotestosterone	—	3.6 × 10⁻⁴	—		PMID 9712896	Open record: Ke 6 (17beta-hydroxysteroid dehydrogenase), 5alpha-dihydrotestosterone
Ke 6 (17beta-hydroxysteroid dehydrogenase)	Mus musculus	estrone	—	3.68 × 10⁻⁴	—		PMID 9712896	Open record: Ke 6 (17beta-hydroxysteroid dehydrogenase), estrone
Ke 6 (17beta-hydroxysteroid dehydrogenase)	Mus musculus	testosterone	—	4.22 × 10⁻⁴	—		PMID 9712896	Open record: Ke 6 (17beta-hydroxysteroid dehydrogenase), testosterone
RoDH (retinol dehydrogenase), human	Homo sapiens	4-androsten-17beta-ol-3-one	—	0.0033	—	pH 7.5, 37 °C	PMID 9188497	Open record: RoDH (retinol dehydrogenase), human, 4-androsten-17beta-ol-3-one
RoDH (retinol dehydrogenase), human	Homo sapiens	5alpha-androstan-17beta-ol-3-one	—	1 × 10⁻⁴	—	pH 7.5, 37 °C	PMID 9188497	Open record: RoDH (retinol dehydrogenase), human, 5alpha-androstan-17beta-ol-3-one
RoDH (retinol dehydrogenase), human	Homo sapiens	5alpha-androstan-3alpha-ol-17-one	—	1 × 10⁻⁴	—	pH 7.5, 37 °C	PMID 9188497	Open record: RoDH (retinol dehydrogenase), human, 5alpha-androstan-3alpha-ol-17-one
RoDH (retinol dehydrogenase), human	Homo sapiens	5alpha-androstane-3alpha,17beta-diol	—	1 × 10⁻⁴	—	pH 7.5, 37 °C	PMID 9188497	Open record: RoDH (retinol dehydrogenase), human, 5alpha-androstane-3alpha,17beta-diol