Values CatLog read from this paper
Characterization of rabbit morphine 6-dehydrogenase and two NAD(+)-dependent 3α(17β)-hydroxysteroid dehydrogenases
PMID 23228597doi:10.1016/j.abb.2012.11.013Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 103 records (309 values) from this paper: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), AKR1C26 (morphine 6-dehydrogenase), AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) from Oryctolagus cuniculus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 1-phenyl-1,2-propanedione | 0.2 | 0.003 | 67 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 1-phenyl-1,2-propanedione |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 16-ketoestrone | 0.157 | 0.003 | 52 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 16-ketoestrone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 2,3-butanedione | 0.118 | 0.21 | 0.5 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 2,3-butanedione |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 2-cyclohexen-1-ol | 0.035 | 0.06 | 0.58 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 2-cyclohexen-1-ol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 4-pregnen-20α-ol-3-one | 0.0048 | 0.076 | 0.067 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 4-pregnen-20α-ol-3-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 4-pregnen-3α-ol-20-one | 0.0057 | 0.0014 | 4 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 4-pregnen-3α-ol-20-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-androstan-17β-ol-3-one | 6.7 × 10⁻⁴ | 0.0052 | 0.12 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-androstan-17β-ol-3-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-androstan-3α-ol-17-one | 0.0092 | 0.058 | 0.15 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-androstan-3α-ol-17-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-androstane-3α,17β-diol | 5 × 10⁻⁴ | 0.0027 | 0.2 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-androstane-3α,17β-diol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-pregnan-20α-ol-3-one | 0.0113 | 0.058 | 0.2 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-pregnan-20α-ol-3-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-pregnan-3α-ol-20-one | 6.7 × 10⁻⁴ | 0.0012 | 0.5 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-pregnan-3α-ol-20-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5β-androstan-17β-ol-3-one | 6.7 × 10⁻⁴ | 0.0032 | 0.22 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 5β-androstan-17β-ol-3-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5β-androstan-3α-ol-17-one | 0.0015 | 0.052 | 0.033 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 5β-androstan-3α-ol-17-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5β-androstane-3α,17β-diol | 0.002 | 0.004 | 0.5 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 5β-androstane-3α,17β-diol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5β-pregnan-3α-ol-20-one | 0.0037 | 0.0074 | 0.5 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 5β-pregnan-3α-ol-20-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one | 0.052 | 0.0042 | 12.3 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 9,10-phenanthrenequinone | 0.152 | 1 × 10⁻⁴ | 1.52 × 10³ | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), 9,10-phenanthrenequinone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | farnesol | 0.0025 | 0.0055 | 0.45 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), farnesol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | geraniol | 0.0118 | 0.019 | 0.62 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), geraniol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | geranylgeraniol | 8.3 × 10⁻⁴ | 8 × 10⁻⁴ | 0.98 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), geranylgeraniol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | isatin | 0.22 | 5 × 10⁻⁴ | 430 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), isatin |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | lithocholic acid | 0.012 | 0.015 | 0.8 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), lithocholic acid |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | morphine | 0.052 | 0.49 | 0.1 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), morphine |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | NAD+ | 0.02 | 0.004 | 5 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), NAD+ |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | NADH | 0.123 | 0.0033 | 37 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), NADH |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | NADP+ | 0.0118 | 0.021 | 0.57 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), NADP+ |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | pyridine-3-aldehyde | 0.085 | 0.3 | 0.33 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), pyridine-3-aldehyde |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | S-(+)-1,2,3,4-tetrahydro-1-naphthol | 0.022 | 0.042 | 0.5 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), S-(+)-1,2,3,4-tetrahydro-1-naphthol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | S-1-indanol | 0.042 | 0.039 | 1.07 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), S-1-indanol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | S-camphorquinone | 0.18 | 0.0029 | 63 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), S-camphorquinone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | testosterone | 0.0017 | 0.0079 | 0.22 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), testosterone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | trans-1,2-dihydronaphthalene-1,2-diol | 0.027 | 0.067 | 0.4 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), trans-1,2-dihydronaphthalene-1,2-diol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | trans-cyclohexa-3,5-diene-1,2-diol | 0.027 | 0.29 | 0.1 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), trans-cyclohexa-3,5-diene-1,2-diol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | α-tetralone | 0.0143 | 0.0038 | 3.8 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), α-tetralone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | β-ionol | 0.009 | 0.0075 | 1.2 | pH 7.4, 25 °C | Open record: AKR1C26 (morphine 6-dehydrogenase), β-ionol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 1-phenyl-1,2-propanedione | 0.45 | 0.005 | 90 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 1-phenyl-1,2-propanedione |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 16-ketoestrone | 0.87 | 0.01 | 87 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 16-ketoestrone |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 17β-estradiol | 0.0063 | 0.1 | 0.067 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 17β-estradiol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 2,3-butanedione | 0.55 | 0.371 | 1.5 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 2,3-butanedione |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 2-cyclohexen-1-ol | 0.105 | 0.67 | 0.15 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 2-cyclohexen-1-ol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 4-pregnen-3α-ol-20-one | 0.0118 | 0.081 | 0.15 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 4-pregnen-3α-ol-20-one |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5α-androstan-17β-ol-3-one | 0.0103 | 0.13 | 0.083 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-androstan-17β-ol-3-one |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5β-androstan-17β-ol-3-one | 0.002 | 0.03 | 0.067 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-androstan-17β-ol-3-one |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5β-pregnan-3α-ol-20-one | 0.023 | 0.17 | 0.13 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-pregnan-3α-ol-20-one |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one | 0.108 | 0.101 | 1 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 9,10-phenanthrenequinone | 0.62 | 2 × 10⁻⁴ | 3.08 × 10³ | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 9,10-phenanthrenequinone |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | geraniol | 0.0153 | 0.57 | 0.033 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), geraniol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | isatin | 0.65 | 0.0011 | 580 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), isatin |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | lithocholic acid | 0.018 | 0.14 | 0.13 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), lithocholic acid |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | NAD+ | 0.28 | 0.012 | 23 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NAD+ |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | NADH | 0.68 | 0.0043 | 108 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NADH |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | NADP+ | 0.103 | 0.068 | 1.52 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NADP+ |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | pyridine-3-aldehyde | 0.2 | 1.1 | 0.17 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), pyridine-3-aldehyde |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | S-(+)-1,2,3,4-tetrahydro-1-naphthol | 0.37 | 0.25 | 1.47 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-(+)-1,2,3,4-tetrahydro-1-naphthol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | S-1-indanol | 0.4 | 0.11 | 3.7 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-1-indanol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | S-camphorquinone | 0.98 | 0.0087 | 113 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-camphorquinone |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | testosterone | 0.0082 | 0.25 | 0.033 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), testosterone |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | trans-cyclohexa-3,5-diene-1,2-diol | 0.127 | 1.11 | 0.12 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), trans-cyclohexa-3,5-diene-1,2-diol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | α-tetralone | 0.2 | 0.15 | 1.3 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), α-tetralone |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant F310I | Oryctolagus cuniculus | 17β-estradiol | 0.025 | 0.029 | 0.87 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant F310I, 17β-estradiol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant F310I | Oryctolagus cuniculus | 5α-androstan-17β-ol-3-one | 0.103 | 0.055 | 1.8 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant F310I, 5α-androstan-17β-ol-3-one |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant F310I | Oryctolagus cuniculus | S-(+)-1,2,3,4-tetrahydro-1-naphthol | 0.147 | 0.13 | 1.13 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant F310I, S-(+)-1,2,3,4-tetrahydro-1-naphthol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant F310I | Oryctolagus cuniculus | testosterone | 0.105 | 0.129 | 0.82 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant F310I, testosterone |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F | Oryctolagus cuniculus | 17β-estradiol | 0.0128 | 0.016 | 0.8 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F, 17β-estradiol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F | Oryctolagus cuniculus | 5α-androstan-17β-ol-3-one | 0.016 | 0.04 | 0.4 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F, 5α-androstan-17β-ol-3-one |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F | Oryctolagus cuniculus | S-(+)-1,2,3,4-tetrahydro-1-naphthol | 0.2 | 0.022 | 9.2 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F, S-(+)-1,2,3,4-tetrahydro-1-naphthol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F | Oryctolagus cuniculus | testosterone | 0.0107 | 0.088 | 0.12 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F, testosterone |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F/F310I | Oryctolagus cuniculus | 17β-estradiol | 0.025 | 0.0026 | 9.7 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F/F310I, 17β-estradiol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F/F310I | Oryctolagus cuniculus | 5α-androstan-17β-ol-3-one | 0.058 | 0.015 | 3.8 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F/F310I, 5α-androstan-17β-ol-3-one |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F/F310I | Oryctolagus cuniculus | S-(+)-1,2,3,4-tetrahydro-1-naphthol | 0.22 | 0.005 | 40 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F/F310I, S-(+)-1,2,3,4-tetrahydro-1-naphthol |
| AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase)variant Y118F/F310I | Oryctolagus cuniculus | testosterone | 0.068 | 0.045 | 1.52 | pH 7.4, 25 °C | Open record: AKR1C27 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) variant Y118F/F310I, testosterone |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 1-phenyl-1,2-propanedione | 0.155 | 8 × 10⁻⁴ | 200 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 1-phenyl-1,2-propanedione |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 16-ketoestrone | 0.27 | 0.0021 | 127 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 16-ketoestrone |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 17β-estradiol | 0.022 | 0.0021 | 10.3 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 17β-estradiol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 2,3-butanedione | 0.23 | 0.19 | 1.2 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 2,3-butanedione |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 2-cyclohexen-1-ol | 0.072 | 0.066 | 1.1 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 2-cyclohexen-1-ol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 4-pregnen-20α-ol-3-one | 0.0038 | 0.019 | 0.2 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 4-pregnen-20α-ol-3-one |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 4-pregnen-3α-ol-20-one | 0.0032 | 0.0073 | 0.43 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 4-pregnen-3α-ol-20-one |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5α-androstan-17β-ol-3-one | 0.065 | 0.0078 | 8.7 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-androstan-17β-ol-3-one |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5α-androstan-3α-ol-17-one | 0.0033 | 0.0023 | 1.48 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-androstan-3α-ol-17-one |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5α-androstane-3α,17β-diol | 0.055 | 0.0078 | 7.2 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-androstane-3α,17β-diol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5α-pregnan-3α-ol-20-one | 0.0072 | 0.0035 | 2 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5α-pregnan-3α-ol-20-one |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5β-androstan-17β-ol-3-one | 0.017 | 0.0076 | 2.2 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-androstan-17β-ol-3-one |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5β-androstan-3α-ol-17-one | 0.0023 | 0.002 | 1.2 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-androstan-3α-ol-17-one |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5β-androstane-3α,17β-diol | 0.0122 | 0.0022 | 5.5 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-androstane-3α,17β-diol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 5β-pregnan-3α-ol-20-one | 0.005 | 0.0036 | 1.38 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 5β-pregnan-3α-ol-20-one |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one | 0.108 | 0.0021 | 52 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | 9,10-phenanthrenequinone | 0.23 | 1 × 10⁻⁴ | 230 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), 9,10-phenanthrenequinone |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | farnesol | 0.027 | 4 × 10⁻⁴ | 67 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), farnesol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | geraniol | 0.028 | 0.0042 | 6.7 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), geraniol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | geranylgeraniol | 0.0127 | 7 × 10⁻⁴ | 18 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), geranylgeraniol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | isatin | 0.18 | 8 × 10⁻⁴ | 230 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), isatin |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | NAD+ | 0.1 | 0.0096 | 15.7 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NAD+ |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | NADH | 0.22 | 0.0026 | 83 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NADH |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | NADP+ | 0.033 | 0.075 | 0.45 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), NADP+ |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | pyridine-3-aldehyde | 0.07 | 0.29 | 0.17 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), pyridine-3-aldehyde |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | S-(+)-1,2,3,4-tetrahydro-1-naphthol | 0.1 | 0.004 | 25 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-(+)-1,2,3,4-tetrahydro-1-naphthol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | S-1-indanol | 0.13 | 0.014 | 9.2 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-1-indanol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | S-camphorquinone | 0.18 | 0.0019 | 97 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), S-camphorquinone |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | testosterone | 0.098 | 0.037 | 2.7 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), testosterone |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | trans-cyclohexa-3,5-diene-1,2-diol | 0.088 | 0.12 | 0.73 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), trans-cyclohexa-3,5-diene-1,2-diol |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | α-tetralone | 0.025 | 0.06 | 0.5 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), α-tetralone |
| AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase) | Oryctolagus cuniculus | β-ionol | 0.028 | 6 × 10⁻⁴ | 47 | pH 7.4, 25 °C | Open record: AKR1C28 (NAD+-dependent 3alpha/17beta-hydroxysteroid dehydrogenase), β-ionol |