EC 1.1.1.218: morphine 6-dehydrogenase
OxidoreductasesOpen in Browse
CatLog read 49 records for EC 1.1.1.218 from 2 papers, for 2 organisms. Names in these papers: AKR1C26 (morphine 6-dehydrogenase), morphine 6-dehydrogenase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 26 records for EC 1.1.1.218 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.218 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Characterization of rabbit morphine 6-dehydrogenase and two NAD(+)-dependent 3α(17β)-hydroxysteroid dehydrogenases | Oryctolagus cuniculus | 35 |
| Purification and characterization of guinea pig liver morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | 14 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 1-phenyl-1,2-propanedione | 0.2 | 0.003 | 67 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 1-phenyl-1,2-propanedione |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 16-ketoestrone | 0.157 | 0.003 | 52 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 16-ketoestrone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 2,3-butanedione | 0.118 | 0.21 | 0.5 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 2,3-butanedione |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 2-cyclohexen-1-ol | 0.035 | 0.06 | 0.58 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 2-cyclohexen-1-ol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 4-pregnen-20α-ol-3-one | 0.0048 | 0.076 | 0.067 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 4-pregnen-20α-ol-3-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 4-pregnen-3α-ol-20-one | 0.0057 | 0.0014 | 4 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 4-pregnen-3α-ol-20-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-androstan-17β-ol-3-one | 6.7 × 10⁻⁴ | 0.0052 | 0.12 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-androstan-17β-ol-3-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-androstan-3α-ol-17-one | 0.0092 | 0.058 | 0.15 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-androstan-3α-ol-17-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-androstane-3α,17β-diol | 5 × 10⁻⁴ | 0.0027 | 0.2 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-androstane-3α,17β-diol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-pregnan-20α-ol-3-one | 0.0113 | 0.058 | 0.2 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-pregnan-20α-ol-3-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5α-pregnan-3α-ol-20-one | 6.7 × 10⁻⁴ | 0.0012 | 0.5 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 5α-pregnan-3α-ol-20-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5β-androstan-17β-ol-3-one | 6.7 × 10⁻⁴ | 0.0032 | 0.22 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 5β-androstan-17β-ol-3-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5β-androstan-3α-ol-17-one | 0.0015 | 0.052 | 0.033 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 5β-androstan-3α-ol-17-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5β-androstane-3α,17β-diol | 0.002 | 0.004 | 0.5 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 5β-androstane-3α,17β-diol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 5β-pregnan-3α-ol-20-one | 0.0037 | 0.0074 | 0.5 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 5β-pregnan-3α-ol-20-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one | 0.052 | 0.0042 | 12.3 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | 9,10-phenanthrenequinone | 0.152 | 1 × 10⁻⁴ | 1.52 × 10³ | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), 9,10-phenanthrenequinone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | farnesol | 0.0025 | 0.0055 | 0.45 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), farnesol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | geraniol | 0.0118 | 0.019 | 0.62 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), geraniol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | geranylgeraniol | 8.3 × 10⁻⁴ | 8 × 10⁻⁴ | 0.98 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), geranylgeraniol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | isatin | 0.22 | 5 × 10⁻⁴ | 430 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), isatin |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | lithocholic acid | 0.012 | 0.015 | 0.8 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), lithocholic acid |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | morphine | 0.052 | 0.49 | 0.1 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), morphine |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | NAD+ | 0.02 | 0.004 | 5 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), NAD+ |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | NADH | 0.123 | 0.0033 | 37 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), NADH |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | NADP+ | 0.0118 | 0.021 | 0.57 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), NADP+ |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | pyridine-3-aldehyde | 0.085 | 0.3 | 0.33 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), pyridine-3-aldehyde |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | S-(+)-1,2,3,4-tetrahydro-1-naphthol | 0.022 | 0.042 | 0.5 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), S-(+)-1,2,3,4-tetrahydro-1-naphthol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | S-1-indanol | 0.042 | 0.039 | 1.07 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), S-1-indanol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | S-camphorquinone | 0.18 | 0.0029 | 63 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), S-camphorquinone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | testosterone | 0.0017 | 0.0079 | 0.22 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), testosterone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | trans-1,2-dihydronaphthalene-1,2-diol | 0.027 | 0.067 | 0.4 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), trans-1,2-dihydronaphthalene-1,2-diol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | trans-cyclohexa-3,5-diene-1,2-diol | 0.027 | 0.29 | 0.1 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), trans-cyclohexa-3,5-diene-1,2-diol |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | α-tetralone | 0.0143 | 0.0038 | 3.8 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), α-tetralone |
| AKR1C26 (morphine 6-dehydrogenase) | Oryctolagus cuniculus | β-ionol | 0.009 | 0.0075 | 1.2 | pH 7.4, 25 °C | PMID 23228597 | Open record: AKR1C26 (morphine 6-dehydrogenase), β-ionol |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Codeine | — | 0.079 | — | 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Codeine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Dihydrocodeine | — | 1.54 | — | 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Dihydrocodeine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Dihydrocodeine | — | 2.11 | — | pH 9.1, 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Dihydrocodeine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Ethylmorphine | — | 0.4 | — | 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Ethylmorphine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Ethylmorphine | — | 1.54 | — | pH 9.1, 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Ethylmorphine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Morphine | — | 0.12 | — | 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Morphine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Morphine | — | 0.49 | — | pH 9.1, 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Morphine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | NAD+ | — | 0.12 | — | 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, NAD+ |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | NADP+100 mM Tricine-NaOH buffer pH 9.1; NADPH formation at 340 nm | — | 0.42 | — | pH 9.1, 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, NADP+ |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | NADP+Tricine-NaOH buffer pH 9.1; Lineweaver-Burk plot (Fig. 7) | — | 0.32 | — | pH 9.1, 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, NADP+ |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Nalorphine | — | 0.015 | — | 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Nalorphine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Nalorphine | — | 0.048 | — | pH 9.1, 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Nalorphine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Normorphine | — | 0.044 | — | 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Normorphine |
| morphine 6-dehydrogenase | Cavia porcellus (guinea pig) | Normorphine | — | 0.15 | — | pH 9.1, 25 °C | PMID 2580834 | Open record: morphine 6-dehydrogenase, Normorphine |