Values CatLog read from this paper
Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes
PMID 10557352doi:10.1073/pnas.96.23.13512Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 30 records (30 values) from this paper: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxysteroid dehydrogenase (3α-HSD) from Homo sapiens, Rattus norvegicus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 1.1.1.50, EC 1.1.1.53, EC 1.1.1.62, EC 1.1.1.64, EC 1.1.1.188, EC 1.1.1.210, EC 1.1.1.239, EC 1.1.1.357
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-pregnan-20-oneno SSRI added | — | 0.0103 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-pregnan-20-one | — | 0.0106 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-pregnan-20-one | — | 0.0086 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-pregnan-20-one | — | 0.0101 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-pregnane-3,20-dioneno SSRI added | — | 5.94 × 10⁻⁵ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-pregnane-3,20-dione | — | 6 × 10⁻⁷ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-pregnane-3,20-dione | — | 1.6 × 10⁻⁶ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-pregnane-3,20-dione | — | 6 × 10⁻⁵ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | 5α-androstan-17β-ol-3-oneno SSRI added | — | 0.00237 | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | 5α-androstan-17β-ol-3-one | — | 5 × 10⁻⁵ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | 5α-androstan-17β-ol-3-one | — | 3.9 × 10⁻⁴ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | 5α-androstan-17β-ol-3-one | — | 0.0178 | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-17β-ol-3-one |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | 5α-androstan-3α,17β-diolno SSRI added | — | 0.001 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | 5α-androstan-3α,17β-diol | — | 0.0072 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | 5α-androstan-3α,17β-diol | — | 4.6 × 10⁻⁴ | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | 5α-androstan-3α,17β-diol | — | 2.1 × 10⁻⁴ | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), 5α-androstan-3α,17β-diol |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | progesteroneno SSRI added | — | 0.1421 | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | progesterone | — | 0.238 | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | progesterone | — | 0.121 | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone |
| 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain) | Homo sapiens | progesterone | — | 0.1499 | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain), progesterone |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-oneno SSRI added | — | 0.043 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-one | — | 0.0309 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-one | — | 0.015 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-one | — | 0.1304 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-one | — | 0.0714 | — | pH 8.9 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dioneno SSRI added | — | 7.2 × 10⁻⁶ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dione | — | 6.3 × 10⁻⁷ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dione | — | 2.6 × 10⁻⁷ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dione | — | 6.9 × 10⁻⁷ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dione | — | 9.93 × 10⁻⁶ | — | pH 7.3, 37 °C | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |