EC 1.1.1.50: 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
OxidoreductasesOpen in Browse
CatLog read 244 records for EC 1.1.1.50 from 12 papers, for 5 organisms. Names in these papers: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9), 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), NADP+-dependent 3α-hydroxysteroid dehydrogenase and 9 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 93 records for EC 1.1.1.50 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.50 in Browse.
Papers
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase) | Rattus norvegicus | 3-oxo-5beta-cholan-24-oic acid | 0.25 | 7 × 10⁻⁴ | 357.2 | pH 7.4 | PMID 3459552 | Open record: 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase), 3-oxo-5beta-cholan-24-oic acid |
| 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase) | Rattus norvegicus | 5beta-cholestane-3alpha,7alpha-diol | 0.062 | 0.0213 | 2.8 | pH 7.4 | PMID 3459552 | Open record: 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase), 5beta-cholestane-3alpha,7alpha-diol |
| 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase) | Rattus norvegicus | 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one | 0.075 | 0.0045 | 16.7 | pH 7.4 | PMID 3459552 | Open record: 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase), 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one |
| 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase) | Rattus norvegicus | 7alpha-hydroxy-5beta-cholestan-3-one100 µM NADPH (100 nmol in 1.0 ml); cosubstrate NADPH | 0.235 | 0.0103 | 22.8 | pH 7.4 | PMID 3459552 | Open record: 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase), 7alpha-hydroxy-5beta-cholestan-3-one |
| 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase) | Rattus norvegicus | 7alpha-hydroxy-5beta-cholestan-3-oneNADH in place of NADPH; cosubstrate NADH | 0.248 | 0.4665 | 0.5 | pH 7.4 | PMID 3459552 | Open record: 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase), 7alpha-hydroxy-5beta-cholestan-3-one |
| 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase) | Rattus norvegicus | Androsterone | 1.078 | 0.0085 | 127 | pH 7.4 | PMID 3459552 | Open record: 3alpha-hydroxysteroid dehydrogenase (7alpha,12alpha-dihydroxy-5beta-cholestan-3-one 3alpha-reductase), Androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3alpha-HSD/CR) | Comamonas testosteroni | androsterone | — | — | 4.3 × 10⁴ | 25 °C | PMID 15572373 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3alpha-HSD/CR), androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3alpha-HSD/CR)variant S114A | Comamonas testosteroni | androsterone | — | — | 7.3 | 25 °C | PMID 15572373 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3alpha-HSD/CR) variant S114A, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3alpha-HSD/CR)variant Y155F | Comamonas testosteroni | androsterone | 1.2 | — | 17 | 25 °C | PMID 15572373 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3alpha-HSD/CR) variant Y155F, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3alpha-HSD/CR)variant Y155F/K159A | Comamonas testosteroni | androsterone | 0.0046 | — | 0.071 | 25 °C | PMID 15572373 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3alpha-HSD/CR) variant Y155F/K159A, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) | Comamonas testosteroni | 2-(1-imidazolyl)-1-(4-methoxyphenyl)-2-methyl-1-propanone | — | 1.807 | — | pH 7 | PMID 10833462 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), 2-(1-imidazolyl)-1-(4-methoxyphenyl)-2-methyl-1-propanone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) | Comamonas testosteroni | 2-methyl-1,2-di-(3-pyridyl)-1-propanone | — | 1.882 | — | pH 7 | PMID 10833462 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), 2-methyl-1,2-di-(3-pyridyl)-1-propanone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) | Comamonas testosteroni | 4-nitrobenzaldehyde | — | 3.286 | — | pH 7 | PMID 10833462 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), 4-nitrobenzaldehyde |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) | Comamonas testosteroni | 5α-dihydrotestosterone | — | 0.0223 | — | pH 7 | PMID 10833462 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), 5α-dihydrotestosterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) | Comamonas testosteroni | androstanedione | — | 0.0422 | — | pH 7 | PMID 10833462 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), androstanedione |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) | Comamonas testosteroni | androsterone | — | 0.0311 | — | pH 8.9 | PMID 10833462 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) | Comamonas testosteroni | cholic acid | — | 0.0184 | — | pH 8.9 | PMID 10833462 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), cholic acid |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) | Comamonas testosteroni | fusidic acid | — | 0.0061 | — | pH 8.9 | PMID 10833462 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), fusidic acid |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193A | Comamonas testosteroni | 2-decalol | — | — | 0.066 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193A, 2-decalol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193A | Comamonas testosteroni | androsterone | — | — | 1.8 × 10³ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193A, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193A | Comamonas testosteroni | cyclohexanol | — | — | 0.0025 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193A, cyclohexanol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193F | Comamonas testosteroni | 2-decalol | 0.9 | 0.906 | 1.1 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193F, 2-decalol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193F | Comamonas testosteroni | androsterone | 508 | 0.0065 | 8 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193F, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193F | Comamonas testosteroni | cyclohexanol | 1 | 30 | 0.032 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193F, cyclohexanol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193F | Comamonas testosteroni | nicotinamide adenine dinucleotide (oxidized) | — | 0.127 | — | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193F, nicotinamide adenine dinucleotide (oxidized) |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193G | Comamonas testosteroni | 2-decalol | — | — | 0.017 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193G, 2-decalol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193G | Comamonas testosteroni | androsterone | — | — | 88 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193G, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193G | Comamonas testosteroni | cyclohexanol | — | — | 0.0041 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193G, cyclohexanol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193I | Comamonas testosteroni | 2-decalol | 1.3 | 1.87 | 0.7 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193I, 2-decalol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193I | Comamonas testosteroni | androsterone | — | — | 1.75 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193I, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193I | Comamonas testosteroni | cyclohexanol | 2.2 | 123 | 0.018 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193I, cyclohexanol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193M | Comamonas testosteroni | 2-decalol | 1.2 | 1.967 | 0.6 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193M, 2-decalol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193M | Comamonas testosteroni | androsterone | 849 | 0.022 | 3.8 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193M, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193M | Comamonas testosteroni | cyclohexanol | 0.9 | 20 | 0.043 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193M, cyclohexanol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193M | Comamonas testosteroni | nicotinamide adenine dinucleotide (oxidized) | — | 0.503 | — | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193M, nicotinamide adenine dinucleotide (oxidized) |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193P | Comamonas testosteroni | 2-decalol | — | — | 0.00119 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193P, 2-decalol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193P | Comamonas testosteroni | androsterone | — | — | 2.12 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193P, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193P | Comamonas testosteroni | cyclohexanol | — | — | 4.1 × 10⁻⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193P, cyclohexanol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193T | Comamonas testosteroni | 2-decalol | — | — | 0.182 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193T, 2-decalol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193T | Comamonas testosteroni | androsterone | — | — | 5.96 × 10³ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193T, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193T | Comamonas testosteroni | cyclohexanol | — | — | 0.0055 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193T, cyclohexanol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193V | Comamonas testosteroni | 2-decalol | — | — | 0.48 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193V, 2-decalol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193V | Comamonas testosteroni | androsterone | 798 | 0.04 | 2 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193V, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193V | Comamonas testosteroni | cyclohexanol | — | — | 0.0124 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193V, cyclohexanol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193V | Comamonas testosteroni | nicotinamide adenine dinucleotide (oxidized) | — | 0.498 | — | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193V, nicotinamide adenine dinucleotide (oxidized) |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193W | Comamonas testosteroni | 2-decalol | — | — | 0.3 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193W, 2-decalol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193W | Comamonas testosteroni | androsterone | 124 | 0.02 | 6.2 × 10³ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193W, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193W | Comamonas testosteroni | cyclohexanol | — | — | 0.0161 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193W, cyclohexanol |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant R201A | Comamonas testosteroni | androsterone | 407 | 0.006 | 6.73 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant R201A, androsterone |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant R201A | Comamonas testosteroni | nicotinamide adenine dinucleotide (oxidized) | — | 0.311 | — | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant R201A, nicotinamide adenine dinucleotide (oxidized) |
| 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant Y202A | Comamonas testosteroni | androsterone | 228 | 0.048 | 4.8 × 10³ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant Y202A, androsterone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) | Rattus norvegicus | 5α-Androstan-3α-ol-17-one | 2.7 | 0.075 | 35.3 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9), 5α-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) | Rattus norvegicus | 5α-Pregnan-3α-ol-20-one | 0.35 | 0.00603 | 57.5 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9), 5α-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) | Rattus norvegicus | 5β-Androstan-3α-ol-17-one | 2.57 | 0.074 | 35 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9), 5β-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) | Rattus norvegicus | 5β-Pregnan-3α-ol-20-one | 1.42 | 0.0264 | 53.8 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9), 5β-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant F118A | Rattus norvegicus | 5α-Androstan-3α-ol-17-one | 0.0117 | 0.367 | 0.033 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant F118A, 5α-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant F118A | Rattus norvegicus | 5α-Pregnan-3α-ol-20-one | 0.0052 | 0.00853 | 0.67 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant F118A, 5α-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant F118A | Rattus norvegicus | 5β-Androstan-3α-ol-17-one | 0.0402 | 0.721 | 0.05 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant F118A, 5β-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant F129A | Rattus norvegicus | 5α-Androstan-3α-ol-17-one | 0.015 | 0.268 | 0.05 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant F129A, 5α-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant F129A | Rattus norvegicus | 5α-Pregnan-3α-ol-20-one | 0.0035 | 0.00451 | 0.83 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant F129A, 5α-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant F129A | Rattus norvegicus | 5β-Androstan-3α-ol-17-one | 0.0247 | 0.397 | 0.067 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant F129A, 5β-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant F129A | Rattus norvegicus | 5β-Pregnan-3α-ol-20-one | — | — | 0.05 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant F129A, 5β-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant L54A | Rattus norvegicus | 5α-Androstan-3α-ol-17-one | 0.162 | 0.205 | 0.83 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant L54A, 5α-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant L54A | Rattus norvegicus | 5α-Pregnan-3α-ol-20-one | 0.0093 | 0.00633 | 1.5 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant L54A, 5α-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant L54A | Rattus norvegicus | 5β-Androstan-3α-ol-17-one | — | — | 0.5 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant L54A, 5β-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant L54A | Rattus norvegicus | 5β-Pregnan-3α-ol-20-one | — | — | 0.33 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant L54A, 5β-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant N306A | Rattus norvegicus | 5α-Androstan-3α-ol-17-one | 0.0403 | 0.186 | 0.22 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant N306A, 5α-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant N306A | Rattus norvegicus | 5α-Pregnan-3α-ol-20-one | 0.0097 | 0.012 | 0.83 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant N306A, 5α-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant N306A | Rattus norvegicus | 5β-Androstan-3α-ol-17-one | 0.192 | 0.288 | 0.67 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant N306A, 5β-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant N306A | Rattus norvegicus | 5β-Pregnan-3α-ol-20-one | 0.1 | 0.121 | 0.83 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant N306A, 5β-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant T226A | Rattus norvegicus | 5α-Androstan-3α-ol-17-one | 1.9 | 0.088 | 22 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant T226A, 5α-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant T226A | Rattus norvegicus | 5α-Pregnan-3α-ol-20-one | 0.438 | 0.00784 | 55.8 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant T226A, 5α-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant T226A | Rattus norvegicus | 5β-Androstan-3α-ol-17-one | 2 | 0.07 | 28.7 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant T226A, 5β-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant T226A | Rattus norvegicus | 5β-Pregnan-3α-ol-20-one | 2.62 | 0.12 | 21.8 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant T226A, 5β-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant T24A | Rattus norvegicus | 5α-Androstan-3α-ol-17-one | 2.93 | 0.122 | 24.2 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant T24A, 5α-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant T24A | Rattus norvegicus | 5α-Pregnan-3α-ol-20-one | 0.25 | 0.00615 | 39.5 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant T24A, 5α-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant T24A | Rattus norvegicus | 5β-Androstan-3α-ol-17-one | 3.3 | 0.276 | 12 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant T24A, 5β-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant T24A | Rattus norvegicus | 5β-Pregnan-3α-ol-20-one | — | — | 12.5 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant T24A, 5β-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant W227A | Rattus norvegicus | 5α-Androstan-3α-ol-17-one | 0.0092 | 0.25 | 0.033 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant W227A, 5α-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant W227A | Rattus norvegicus | 5α-Pregnan-3α-ol-20-one | 0.0013 | 0.00605 | 0.22 calc. | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant W227A, 5α-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant W227A | Rattus norvegicus | 5β-Androstan-3α-ol-17-one | 0.048 | 0.755 | 0.067 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant W227A, 5β-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant W227A | Rattus norvegicus | 5β-Pregnan-3α-ol-20-one | 0.047 | 0.132 | 0.33 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant W227A, 5β-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant Y310A | Rattus norvegicus | 5α-Androstan-3α-ol-17-one | 0.0812 | 0.529 | 0.15 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant Y310A, 5α-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant Y310A | Rattus norvegicus | 5α-Pregnan-3α-ol-20-one | 0.018 | 0.00636 | 2.8 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant Y310A, 5α-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant Y310A | Rattus norvegicus | 5β-Androstan-3α-ol-17-one | — | — | 1.8 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant Y310A, 5β-Androstan-3α-ol-17-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9)variant Y310A | Rattus norvegicus | 5β-Pregnan-3α-ol-20-one | — | — | 2.2 | pH 7, 37 °C | PMID 12604226 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD or AKR1C9) variant Y310A, 5β-Pregnan-3α-ol-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-pregnan-20-oneno SSRI added | — | 0.0103 | — | pH 8.9 | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-pregnan-20-one | — | 0.0106 | — | pH 8.9 | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-pregnan-20-one | — | 0.0086 | — | pH 8.9 | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-pregnan-20-one | — | 0.0101 | — | pH 8.9 | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-pregnane-3,20-dioneno SSRI added | — | 5.94 × 10⁻⁵ | — | pH 7.3, 37 °C | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-pregnane-3,20-dione | — | 6 × 10⁻⁷ | — | pH 7.3, 37 °C | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-pregnane-3,20-dione | — | 1.6 × 10⁻⁶ | — | pH 7.3, 37 °C | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-pregnane-3,20-dione | — | 6 × 10⁻⁵ | — | pH 7.3, 37 °C | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | 3-dehydro-α-ecdysone | — | 0.028 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), 3-dehydro-α-ecdysone |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | 3α-hydroxy-desogestrel | — | 0.0216 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), 3α-hydroxy-desogestrel |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | 5α-dihydrotestosterone | — | 0.019 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), 5α-dihydrotestosterone |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | 5α-pregnanolone | — | 0.0257 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), 5α-pregnanolone |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | 5β-dihydrotestosterone | — | 0.0201 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), 5β-dihydrotestosterone |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | 5β-pregnanolone | — | 0.0235 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), 5β-pregnanolone |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | androsterone | — | 0.0267 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), androsterone |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | cholic acid | — | 0.025 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), cholic acid |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | fusidic acid | — | 0.0068 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), fusidic acid |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | metyrapone | — | 0.63 | — | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), metyrapone | |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | p-nitroacetophenone | — | 1 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), p-nitroacetophenone |
| 3α-hydroxysteroid dehydrogenase (HSD 29) | Pseudomonas sp. | p-nitrobenzaldehyde | — | 1 | — | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase (HSD 29), p-nitrobenzaldehyde | |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-oneno SSRI added | — | 0.043 | — | pH 8.9 | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-one | — | 0.0309 | — | pH 8.9 | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-one | — | 0.015 | — | pH 8.9 | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-one | — | 0.1304 | — | pH 8.9 | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 3α-hydroxy-5α-pregnan-20-one | — | 0.0714 | — | pH 8.9 | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 3α-hydroxy-5α-pregnan-20-one |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dioneno SSRI added | — | 7.2 × 10⁻⁶ | — | pH 7.3, 37 °C | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dione | — | 6.3 × 10⁻⁷ | — | pH 7.3, 37 °C | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dione | — | 2.6 × 10⁻⁷ | — | pH 7.3, 37 °C | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dione | — | 6.9 × 10⁻⁷ | — | pH 7.3, 37 °C | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III) | Homo sapiens | 5α-pregnane-3,20-dione | — | 9.93 × 10⁻⁶ | — | pH 7.3, 37 °C | PMID 10557352 | Open record: 3α-hydroxysteroid dehydrogenase type III (3α-HSD type III), 5α-pregnane-3,20-dione |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) | Comamonas testosteroni | androsterone | 299 | 0.0038 | 7.9 × 10⁴ | pH 10.2, 25 °C | PMID 19683506 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR), androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant D249A | Comamonas testosteroni | androsterone | 41 | 0.016 | 2.6 × 10³ | pH 10.2, 25 °C | PMID 19683506 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant D249A, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant D249K | Comamonas testosteroni | androsterone | 0.5 | 0.009 | 56 | pH 10.2, 25 °C | PMID 19683506 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant D249K, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant D249S | Comamonas testosteroni | androsterone | 286 | 0.005 | 5.8 × 10⁴ | pH 10.2, 25 °C | PMID 19683506 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant D249S, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193A | Comamonas testosteroni | 2-decalol | — | — | 0.066 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193A, 2-decalol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193A | Comamonas testosteroni | androsterone | — | — | 1.8 × 10³ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193A, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193A | Comamonas testosteroni | cyclohexanol | — | — | 0.0025 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193A, cyclohexanol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193F | Comamonas testosteroni | 2-decalol | — | — | 1.1 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193F, 2-decalol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193F | Comamonas testosteroni | androsterone | — | — | 8 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193F, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193F | Comamonas testosteroni | cyclohexanol | — | — | 0.032 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193F, cyclohexanol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193G | Comamonas testosteroni | 2-decalol | — | — | 0.017 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193G, 2-decalol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193G | Comamonas testosteroni | androsterone | — | — | 88 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193G, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193G | Comamonas testosteroni | cyclohexanol | — | — | 0.0041 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193G, cyclohexanol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193I | Comamonas testosteroni | 2-decalol | — | — | 0.7 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193I, 2-decalol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193I | Comamonas testosteroni | androsterone | — | — | 1.75 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193I, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193I | Comamonas testosteroni | cyclohexanol | — | — | 0.018 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193I, cyclohexanol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193M | Comamonas testosteroni | 2-decalol | — | — | 0.6 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193M, 2-decalol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193M | Comamonas testosteroni | androsterone | — | — | 3.8 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193M, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193M | Comamonas testosteroni | cyclohexanol | — | — | 0.043 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193M, cyclohexanol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193P | Comamonas testosteroni | 2-decalol | — | — | 0.00119 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193P, 2-decalol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193P | Comamonas testosteroni | androsterone | — | — | 2.12 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193P, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193P | Comamonas testosteroni | cyclohexanol | — | — | 4.1 × 10⁻⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193P, cyclohexanol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193T | Comamonas testosteroni | 2-decalol | — | — | 0.182 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193T, 2-decalol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193T | Comamonas testosteroni | androsterone | — | — | 5.96 × 10³ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193T, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193T | Comamonas testosteroni | cyclohexanol | — | — | 0.0055 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193T, cyclohexanol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193V | Comamonas testosteroni | 2-decalol | — | — | 0.48 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193V, 2-decalol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193V | Comamonas testosteroni | androsteroneTable 1 | — | — | 2 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193V, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193V | Comamonas testosteroni | androsteronein the text | — | 0.04 | — | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193V, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193V | Comamonas testosteroni | cyclohexanol | — | — | 0.0124 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193V, cyclohexanol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193W | Comamonas testosteroni | 2-decalol | — | — | 0.3 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193W, 2-decalol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193W | Comamonas testosteroni | androsterone | — | — | 6.2 × 10³ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193W, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant L193W | Comamonas testosteroni | cyclohexanol | — | — | 0.0161 | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant L193W, cyclohexanol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant R201A | Comamonas testosteroni | androsterone | — | — | 6.73 × 10⁴ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant R201A, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR)variant Y202A | Comamonas testosteroni | androsterone | — | — | 4.8 × 10³ | pH 10.5, 25 °C | PMID 41940686 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) variant Y202A, androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | 2-(1-imidazolyl)-1-(4-methoxyphenyl)-2-methyl-1-propanone | — | 1 | — | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), 2-(1-imidazolyl)-1-(4-methoxyphenyl)-2-methyl-1-propanone | |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | 3-dehydro-α-ecdysone | — | 0.025 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), 3-dehydro-α-ecdysone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | 3-dehydro-β-ecdysone | — | 0.035 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), 3-dehydro-β-ecdysone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | 3α-hydroxy-desogestrel | — | 0.0152 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), 3α-hydroxy-desogestrel |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | 5α-dihydrotestosterone | — | 0.0161 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), 5α-dihydrotestosterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | 5α-pregnanolone | — | 0.0287 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), 5α-pregnanolone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | 5β-dihydrotestosterone | — | 0.0111 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), 5β-dihydrotestosterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | 5β-pregnanolone | — | 0.022 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), 5β-pregnanolone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | androstandiol | — | 0.0328 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), androstandiol |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | androstandione | — | 0.0357 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), androstandione |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | androsterone | — | 0.0244 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), androsterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | cholic acid | — | 0.0301 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), cholic acid |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | epiandrosterone | — | 0.0207 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), epiandrosterone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | fusidic acid | — | 0.003 | — | pH 8.9 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), fusidic acid |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | metyrapol | — | 2.1 | — | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), metyrapol | |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | metyrapone | — | 0.61 | — | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), metyrapone | |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | p-nitroacetophenone | — | 0.9 | — | pH 7 | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), p-nitroacetophenone |
| 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28) | Comamonas testosteroni | p-nitrobenzaldehyde | — | 1.09 | — | PMID 8944761 | Open record: 3α-hydroxysteroid dehydrogenase/carbonyl reductase (HSD 28), p-nitrobenzaldehyde | |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-androstan-17-onerecombinant | 1.26 | 0.0463 | 27 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 3α-hydroxy-5α-androstan-17-one |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 3α-hydroxy-5α-androstan-17-onepurified from rat liver (native enzyme) | 2.17 | 0.057 | 38 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 3α-hydroxy-5α-androstan-17-one |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 4-Nitroacetophenonerecombinant | 1.09 | 0.23 | 5 | pH 6, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 4-Nitroacetophenone |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 4-Nitroacetophenonepurified from rat liver (native enzyme) | 1.31 | 0.134 | 10 | pH 6, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 4-Nitroacetophenone |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 4-Nitrobenzaldehyderecombinant | 1.1 | 0.044 | 25 | pH 6, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 4-Nitrobenzaldehyde |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 4-Nitrobenzaldehydepurified from rat liver (native enzyme) | 2.02 | 0.0555 | 37 | pH 6, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 4-Nitrobenzaldehyde |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-androstan-3,17-dionerecombinant | 0.28 | 0.0041 | 68 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 5α-androstan-3,17-dione |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 5α-androstan-3,17-dionepurified from rat liver (native enzyme) | 0.54 | 0.0063 | 85 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 5α-androstan-3,17-dione |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 9,10-Phenanthrenequinonerecombinant | 2.22 | 0.0013 | 1.7 × 10³ | pH 6, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 9,10-Phenanthrenequinone |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | 9,10-Phenanthrenequinonepurified from rat liver (native enzyme) | 3.62 | 0.0019 | 1.9 × 10³ | pH 6, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), 9,10-Phenanthrenequinone |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | NAD+recombinant | 1.14 | 0.94 | 1.2 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), NAD+ |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | NAD+purified from rat liver (native enzyme) | 2.05 | 0.725 | 2.8 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), NAD+ |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | NADHrecombinant | 0.29 | 0.0267 | 12 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), NADH |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | NADHpurified from rat liver (native enzyme) | 0.43 | 0.0267 | 17 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), NADH |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | trans-1,2-dihydroxy-3,5-cyclohexadienerecombinant | 1.18 | 1.4 | 0.83 | pH 9, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), trans-1,2-dihydroxy-3,5-cyclohexadiene |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) | Rattus norvegicus | trans-1,2-dihydroxy-3,5-cyclohexadienepurified from rat liver (native enzyme) | 1.7 | 1.4 | 1.2 | pH 9, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD), trans-1,2-dihydroxy-3,5-cyclohexadiene |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C170A | Rattus norvegicus | 3α-hydroxy-5α-androstan-17-one | 2.07 | 0.0429 | 50 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C170A, 3α-hydroxy-5α-androstan-17-one |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C170A | Rattus norvegicus | 5α-androstan-3,17-dione | 0.45 | 0.0035 | 130 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C170A, 5α-androstan-3,17-dione |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C170A | Rattus norvegicus | NAD+ | 1.68 | 0.86 | 2 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C170A, NAD+ |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C170A | Rattus norvegicus | NADH | 0.42 | 0.0231 | 18 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C170A, NADH |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C217A | Rattus norvegicus | 3α-hydroxy-5α-androstan-17-one | 1.19 | 0.0652 | 18 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C217A, 3α-hydroxy-5α-androstan-17-one |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C217A | Rattus norvegicus | 5α-androstan-3,17-dione | 0.53 | 0.0187 | 28 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C217A, 5α-androstan-3,17-dione |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C217A | Rattus norvegicus | NAD+ | 0.85 | 0.71 | 1.3 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C217A, NAD+ |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C217A | Rattus norvegicus | NADH | 0.43 | 0.0505 | 8.3 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C217A, NADH |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C242A | Rattus norvegicus | 3α-hydroxy-5α-androstan-17-one | 1.47 | 0.0298 | 50 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C242A, 3α-hydroxy-5α-androstan-17-one |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C242A | Rattus norvegicus | 5α-androstan-3,17-dione | 0.41 | 0.0058 | 70 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C242A, 5α-androstan-3,17-dione |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C242A | Rattus norvegicus | NAD+ | 1.59 | 1 | 1.7 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C242A, NAD+ |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant C242A | Rattus norvegicus | NADH | 0.36 | 0.0205 | 18 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant C242A, NADH |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant Y205F | Rattus norvegicus | 3α-hydroxy-5α-androstan-17-one | 1.14 | 0.0292 | 40 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant Y205F, 3α-hydroxy-5α-androstan-17-one |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant Y205F | Rattus norvegicus | 5α-androstan-3,17-dione | 0.27 | 0.0042 | 65 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant Y205F, 5α-androstan-3,17-dione |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant Y205F | Rattus norvegicus | NAD+ | 1.43 | 0.83 | 1.7 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant Y205F, NAD+ |
| 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD)variant Y205F | Rattus norvegicus | NADH | 0.36 | 0.0303 | 12 | pH 7, 25 °C | PMID 8175784 | Open record: 3α-hydroxysteroid/dihydrodiol dehydrogenase (3α-HSD) variant Y205F, NADH |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 1-Phenyl-1,2-propanedione | — | 0.41 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 1-Phenyl-1,2-propanedione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 17α,21-Dihydroxy-5β-pregnane-3,11,20-trione | — | 0.0017 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 17α,21-Dihydroxy-5β-pregnane-3,11,20-trione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 17β-Hydroxy-5α-androstan-3-one | — | 0.0024 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 17β-Hydroxy-5α-androstan-3-one |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 17β-Hydroxy-5β-androstan-3-one | — | 0.0015 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 17β-Hydroxy-5β-androstan-3-one |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 2,3-Butanedione | — | 0.8 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 2,3-Butanedione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 2,3-Heptanedione | — | 0.077 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 2,3-Heptanedione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 2,3-Hexanedione | — | 0.21 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 2,3-Hexanedione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 2,3-Pentanedione | — | 0.43 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 2,3-Pentanedione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 2-Nitrobenzaldehyde | — | 0.2 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 2-Nitrobenzaldehyde |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 3-Oxo-5β-cholan-24-oic acid | — | 7 × 10⁻⁴ | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 3-Oxo-5β-cholan-24-oic acid |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 3α,17α,21-Trihydroxy-5β-pregnane-11,20-dione | — | 0.167 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 3α,17α,21-Trihydroxy-5β-pregnane-11,20-dione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 3α,21-Dihydroxy-5β-pregnan-20-one | — | 0.011 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 3α,21-Dihydroxy-5β-pregnan-20-one |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 3α-hydroxy-5α-androstan-17-one | — | 0.0095 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 3α-hydroxy-5α-androstan-17-one |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 3α-hydroxy-5α-androstan-17-one | — | 0.0091 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 3α-hydroxy-5α-androstan-17-one |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 3α-Hydroxy-5β-androstan-17-one | — | 0.025 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 3α-Hydroxy-5β-androstan-17-one |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 3α-hydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide | — | 0.0052 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 3α-hydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 3α-Hydroxy-5β-pregnan-20-one | — | 0.0079 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 3α-Hydroxy-5β-pregnan-20-one |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 4-Nitroacetophenone | — | 0.55 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 4-Nitroacetophenone |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 4-Nitrobenzaldehyde | — | 0.083 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 4-Nitrobenzaldehyde |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 5α-Androstane-3,17-dione | — | 4.9 × 10⁻⁴ | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 5α-Androstane-3,17-dione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 5α-androstane-3,17-dione | — | 4.2 × 10⁻⁴ | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 5α-androstane-3,17-dione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 5α-Androstane-3α,17β-diol | — | 0.016 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 5α-Androstane-3α,17β-diol |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 5α-Pregnane-2,20-dione | — | 4.8 × 10⁻⁴ | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 5α-Pregnane-2,20-dione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 5β-Androstane-3,17-dione | — | 3.5 × 10⁻⁴ | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 5β-Androstane-3,17-dione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 5β-Androstane-3α,17β-diol | — | 0.012 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 5β-Androstane-3α,17β-diol |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | 5β-Pregnane-3,20-dione | — | 3.8 × 10⁻⁴ | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, 5β-Pregnane-3,20-dione |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | Acenaphthequinone | — | 0.0012 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, Acenaphthequinone |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | Benzene dihydrodiol | — | 6.7 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, Benzene dihydrodiol |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | Camphorquinone | — | 0.031 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, Camphorquinone |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | NADP+ | — | 0.012 | — | pH 9.5, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, NADP+ |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | NADP+ | — | 0.0167 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, NADP+ |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | NADPH100 mM potassium phosphate buffer | — | 9.7 × 10⁻⁴ | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, NADPH |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | NADPH100 mM potassium phosphate | — | 8.5 × 10⁻⁴ | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, NADPH |
| NADP+-dependent 3α-hydroxysteroid dehydrogenase | Mus musculus | Pyridine-4-aldehyde | — | 0.61 | — | pH 7, 25 °C | PMID 3170514 | Open record: NADP+-dependent 3α-hydroxysteroid dehydrogenase, Pyridine-4-aldehyde |
| NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR) | Rattus norvegicus | 3α-hydroxy-5α-pregnan-20-one | — | 0.0014 | — | pH 7.2, 37 °C | PMID 2268552 | Open record: NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR), 3α-hydroxy-5α-pregnan-20-one |
| NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR) | Rattus norvegicus | 5α-pregnane-3,20-dione10 µg/ml bovine gamma globulin | — | 8 × 10⁻⁵ | — | pH 7.2, 37 °C | PMID 2268552 | Open record: NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR), 5α-pregnane-3,20-dione |
| NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR) | Rattus norvegicus | 5α-pregnane-3,20-dione5α-DHP varied (50-1000 nM) with saturating NADPH | — | 1.38 × 10⁻⁴ | — | pH 7.2, 37 °C | PMID 2268552 | Open record: NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR), 5α-pregnane-3,20-dione |
| NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR) | Rattus norvegicus | NADP+ | — | 0.0016 | — | pH 7.2, 37 °C | PMID 2268552 | Open record: NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR), NADP+ |
| NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR) | Rattus norvegicus | NADPH | — | 7.1 × 10⁻⁴ | — | pH 7.2, 37 °C | PMID 2268552 | Open record: NADPH:5α-dihydroprogesterone 3α-hydroxysteroid oxidoreductase (3α-HSOR), NADPH |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | 6-tert-butyl-2,3-epoxy-4(S)-hydroxy-5-cyclohexen-1-one | 0.102 | 3.6 | 0.028 calc. | pH 7.4, 25 °C | PMID 16788056 | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), 6-tert-butyl-2,3-epoxy-4(S)-hydroxy-5-cyclohexen-1-one |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione | 0.4 | 0.023 | 17 calc. | pH 7.4, 25 °C | PMID 16788056 | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | trans-1,2-dihydrobenzene-1,2-diol | 0.06 | 0.37 | 0.16 calc. | pH 7.4, 25 °C | PMID 16788056 | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), trans-1,2-dihydrobenzene-1,2-diol |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | α-3-Hydroxyhexobarbital | 0.05 | 1.6 | 0.031 calc. | pH 7.4, 25 °C | PMID 16788056 | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), α-3-Hydroxyhexobarbital |
| rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2) | Rattus norvegicus | β-3-Hydroxyhexobarbital | 0.078 | 2.5 | 0.031 calc. | pH 7.4, 25 °C | PMID 16788056 | Open record: rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD, AKR1C9; identified as TBER2), β-3-Hydroxyhexobarbital |