CatLogenzyme kinetics catalog

EC 1.1.1.62: 17beta-estradiol 17-dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 275 records for EC 1.1.1.62 from 24 papers, for 4 organisms. Names in these papers: DHRS11 (dehydrogenase/reductase SDR family member 11), AKR1C1, dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase), AKR1C2 and 21 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 64 records for EC 1.1.1.62 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.62 in Browse.

Papers

PaperOrganismsRecords
Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesteroneHomo sapiens71
Human dehydrogenase/reductase (SDR family) member 11 is a novel type of 17β-hydroxysteroid dehydrogenaseHomo sapiens46
Mouse liver dihydrodiol dehydrogenases. Identity of the predominant and a minor form with 17 beta-hydroxysteroid dehydrogenase and aldehyde reductaseMus musculus26
Characterization of structural and functional properties of human 17 beta-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesisHomo sapiens18
Human placental estradiol-17 beta dehydrogenase. II. Kinetics and substrate specificitiesHomo sapiens14
Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymesHomo sapiens12
Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolismHomo sapiens12
Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostateHomo sapiens, Rattus norvegicus11
Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization…Homo sapiens9
Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone…Homo sapiens7
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target…Homo sapiens6
Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activityHomo sapiens6
Molecular characterization of a first human 3(alpha-->beta)-hydroxysteroid epimeraseHomo sapiens5
A new branch of mammalian vitamin B6 metabolism: AKR1C-mediated conversion of pyridoxal to pyridoxine and 4-pyridoxolactoneHomo sapiens5
Dimerization and enzymatic activity of fungal 17beta-hydroxysteroid dehydrogenase from the short-chain dehydrogenase/reductase superfamilyCochliobolus lunatus4
Rational design of novel mutants of fungal 17beta-hydroxysteroid dehydrogenaseCochliobolus lunatus4
Factorizing the role of a critical leucine residue in the binding of substrate to human 20alpha-hydroxysteroid dehydrogenase (AKR1C1): molecular modeling and kinetic studies of the Leu308Val mutant…Homo sapiens4
Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activityHomo sapiens4
Characterization of Ke 6, a new 17beta-hydroxysteroid dehydrogenase, and its expression in gonadal tissuesMus musculus4
Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7Homo sapiens2
Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate…Homo sapiens2
Complementary deoxyribonucleic acid cloning and enzymatic characterization of a novel 17beta/3alpha-hydroxysteroid/retinoid short chain dehydrogenase/reductaseMus musculus1
Kinetic studies of AKR1B10, human aldose reductase-like protein: endogenous substrates and inhibition by steroidsHomo sapiens1
Substrate specificity and inhibitor sensitivity of rabbit 20α-hydroxysteroid dehydrogenaseHomo sapiens1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
17beta-hydroxysteroid dehydrogenase type 1Homo sapiens17beta-estradiolpurified (Reactive Red-agarose, Mono Q)—0.00211—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1Homo sapiens17beta-estradiol—0.00229—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1Homo sapiensestronepurified (Reactive Red-agarose, Mono Q)—9 × 10⁻⁴—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1Homo sapiensestrone—0.00138—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant E282AHomo sapiens17beta-estradiol—0.00163—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant E282AHomo sapiensestrone—0.00113—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant E282QHomo sapiens17beta-estradiol—0.0018—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant E282QHomo sapiensestrone—6.6 × 10⁻⁴—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant H221A/E282AHomo sapiens17beta-estradiol—0.00374—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant H221A/E282AHomo sapiensestrone—0.00511—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant H221A/E282QHomo sapiens17beta-estradiol—0.00428—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant H221A/E282QHomo sapiensestrone—0.00375—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant K159AHomo sapiens17beta-estradiol—0.00539—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant K159AHomo sapiensestrone—0.00114—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant S134AHomo sapiens17beta-estradiol—0.00253—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant S134AHomo sapiensestrone—7.8 × 10⁻⁴—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant S142AHomo sapiens17beta-estradiol—0.00526—pH 7.5, 37 °CPMID 8994190Open
17beta-hydroxysteroid dehydrogenase type 1variant S142AHomo sapiensestrone—0.00166—pH 7.5, 37 °CPMID 8994190Open
17beta/3alpha-hydroxysteroid/retinoid short chain dehydrogenase/reductase (17bHSD9)Mus musculusall-trans-retinol—0.0032—pH 9, 37 °CPMID 10537158Open
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)Rattus norvegicus4-androsten-17beta-ol-3-one—0.0011—pH 7.5, 37 °CPMID 9188497Open
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)Rattus norvegicus5alpha-androstan-17beta-ol-3-one—5 × 10⁻⁴—pH 7.5, 37 °CPMID 9188497Open
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)Rattus norvegicus5alpha-androstan-3alpha-ol-17-one—2 × 10⁻⁴—pH 7.5, 37 °CPMID 9188497Open
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)Rattus norvegicus5alpha-androstane-3alpha,17beta-diol—1 × 10⁻⁴—pH 7.5, 37 °CPMID 9188497Open
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)Rattus norvegicusEstradiol—8 × 10⁻⁴—pH 7.5, 37 °CPMID 9188497Open
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)Rattus norvegicusNAD+—0.003—pH 7.5, 37 °CPMID 9188497Open
17β-HSD6 (17β-hydroxysteroid dehydrogenase type 6)Rattus norvegicusNADP+—1—pH 7.5, 37 °CPMID 9188497Open
17β-hydroxysteroid dehydrogenase (17β-HSDcl)Cochliobolus lunatusNADP+0.656 × 10⁻⁵1.1 × 10⁴pH 8, 25 °CPMID 16359545Open
17β-hydroxysteroid dehydrogenase (17β-HSDcl)Cochliobolus lunatusNADPH3.80.0065580pH 8, 25 °CPMID 16359545Open
17β-hydroxysteroid dehydrogenase (17β-HSDcl)variant H111ACochliobolus lunatusNADP+0.90.0046190pH 8, 25 °CPMID 16359545Open
17β-hydroxysteroid dehydrogenase (17β-HSDcl)variant H111ACochliobolus lunatusNADPH2.40.050647pH 8, 25 °CPMID 16359545Open
17β-hydroxysteroid dehydrogenase (17β-HSDcl)variant H164GCochliobolus lunatusNADP+4.72.8 × 10⁻⁴1.6 × 10⁴pH 8, 25 °CPMID 17196285Open
17β-hydroxysteroid dehydrogenase (17β-HSDcl)variant H164GCochliobolus lunatusNADPH1.93.5 × 10⁻⁴5.5 × 10³pH 8, 25 °CPMID 17196285Open
17β-hydroxysteroid dehydrogenase (17β-HSDcl)variant H164WCochliobolus lunatusNADP+3.11.9 × 10⁻⁴1.6 × 10⁴pH 8, 25 °CPMID 17196285Open
17β-hydroxysteroid dehydrogenase (17β-HSDcl)variant H164WCochliobolus lunatusNADPH1.84 × 10⁻⁴4.5 × 10³pH 8, 25 °CPMID 17196285Open
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens11-dehydrocorticosterone5 × 10⁻⁴0.00170.3pH 9.3, 25 °CPMID 12917011Open
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens3-hydroxybutyryl-CoA4.830.085257pH 9.3, 25 °CPMID 12917011Open
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens3α,7α-dihydroxy-5β-cholan-24-oic acid5.7 × 10⁻⁴0.03640.017pH 9.3, 25 °CPMID 12917011Open
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens3β,7β-dihydroxy-5β-cholan-24-oic acid9 × 10⁻⁴0.2190.0033pH 9.3, 25 °CPMID 12917011Open
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens5α-androstan-3α-ol-17-one6.7 × 10⁻⁴0.0410.017pH 9.3, 25 °CPMID 12917011Open
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens5α-pregnan-20β-ol-3-one0.00420.0050.88pH 9.3, 25 °CPMID 12917011Open
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiensacetoacetyl-CoA23.80.0257927pH 7, 25 °CPMID 12917011Open
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiensNAD+—0.0423—pH 9.3, 25 °CPMID 12917011Open
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiensNADH—0.0306—pH 7, 25 °CPMID 12917011Open
17β-hydroxysteroid dehydrogenase type 2Homo sapiens(17β)-estra-1,3,5(10)-triene-3,17-diol—2.1 × 10⁻⁴—pH 7.4, 37 °CPMID 8099587Open
17β-hydroxysteroid dehydrogenase type 2Homo sapiens17β-hydroxy-4-androsten-3-one—3.9 × 10⁻⁴—pH 7.4, 37 °CPMID 8099587Open
17β-hydroxysteroid dehydrogenase type 2Homo sapiens17β-hydroxy-5α-androstan-3-one—3.1 × 10⁻⁴—pH 7.4, 37 °CPMID 8099587Open
17β-hydroxysteroid dehydrogenase type 2Homo sapiens20α-hydroxypregn-4-ene-3-one—7.1 × 10⁻⁴—pH 7.4, 37 °CPMID 8099587Open
17β-hydroxysteroid dehydrogenase type 2Homo sapiens3-hydroxyestra-1,3,5(10)-trien-17-one—7.8 × 10⁻⁴—pH 7.4, 37 °CPMID 8099587Open
17β-hydroxysteroid dehydrogenase type 2Homo sapiensandrost-4-ene-3,17-dione—0.00263—pH 7.4, 37 °CPMID 8099587Open
17β-hydroxysteroid dehydrogenase type 7 (h17HSD7)Homo sapiens5α-dihydrotestosterone—0.0026—PMID 12732193Open
17β-hydroxysteroid dehydrogenase type 7 (h17HSD7)Homo sapiensestrone—0.00325—PMID 12732193Open
20α-hydroxysteroid dehydrogenase (AKR1C1)Homo sapiensβ-Ionol0.0530.001244 calc.pH 7.4, 25 °CPMID 23995665Open
20α-hydroxysteroid dehydrogenase (AKR1C1)variant L308AHomo sapiens(S)-1,2,3,4-tetrahydronaphthalen-1-ol—0.470.83pH 7.4, 25 °CPMID 20656485Open
20α-hydroxysteroid dehydrogenase (AKR1C1)variant L308VHomo sapiens(S)-1,2,3,4-tetrahydronaphthalen-1-ol—0.01613pH 7.4, 25 °CPMID 20656485Open
20α-hydroxysteroid dehydrogenase (AKR1C1)variant L308VHomo sapiens5α-pregnane-3α,20α-diol—4 × 10⁻⁴270pH 7.4, 25 °CPMID 20656485Open
20α-hydroxysteroid dehydrogenase (AKR1C1)variant L308VHomo sapiens5β-pregnan-3α-ol-20-one—0.006227pH 7.4, 25 °CPMID 20656485Open
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)Homo sapiens5α-androstane-3,17-dioneproduct: ADT (androsterone)—4 × 10⁻⁴—pH 7.4, 37 °CPMID 10896656Open
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)Homo sapiens5α-androstane-3,17-dioneproduct: epi-ADT (epi-androsterone)—2 × 10⁻⁴—pH 7.4, 37 °CPMID 10896656Open
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)Homo sapiens5α-androstane-3β-ol-17-one—0.0017—pH 7.4, 37 °CPMID 10896656Open
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)Homo sapiens5α-pregnane-3α-ol-20-one—0.003—pH 7.4, 37 °CPMID 10896656Open
3(α→β)-hydroxysteroid epimerase (3(α→β)-HSE)Homo sapiensandrosterone—4 × 10⁻⁴—pH 7.4, 37 °CPMID 10896656Open
3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)Homo sapiens5α-dihydrotestosterone0.06120.0021828pH 7.4, 37 °CPMID 24434280Open
3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)Homo sapiensprogesterone0.00358.4 × 10⁻⁴4.2pH 7.4, 37 °CPMID 24434280Open
3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)variant V54LHomo sapiens5α-dihydrotestosterone0.11530.071031.7pH 7.4, 37 °CPMID 24434280Open
3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)variant V54LHomo sapiensprogesterone0.03920.0021318.3pH 7.4, 37 °CPMID 24434280Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiens5α-androstan-17β-ol-3-oneno SSRI added—0.00237—pH 7.3, 37 °CPMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiens5α-androstan-17β-ol-3-one—5 × 10⁻⁵—pH 7.3, 37 °CPMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiens5α-androstan-17β-ol-3-one—3.9 × 10⁻⁴—pH 7.3, 37 °CPMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiens5α-androstan-17β-ol-3-one—0.0178—pH 7.3, 37 °CPMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiens5α-androstan-3α,17β-diolno SSRI added—0.001—pH 8.9PMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiens5α-androstan-3α,17β-diol—0.0072—pH 8.9PMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiens5α-androstan-3α,17β-diol—4.6 × 10⁻⁴—pH 8.9PMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiens5α-androstan-3α,17β-diol—2.1 × 10⁻⁴—pH 8.9PMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiensprogesteroneno SSRI added—0.1421—pH 7.3, 37 °CPMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiensprogesterone—0.238—pH 7.3, 37 °CPMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiensprogesterone—0.121—pH 7.3, 37 °CPMID 10557352Open
3α-hydroxysteroid dehydrogenase type IIBrain (3α-HSD type IIBrain)Homo sapiensprogesterone—0.1499—pH 7.3, 37 °CPMID 10557352Open
AKR1C1Homo sapiens(S)-1,2,3,4-tetrahydro-1-naphthol0.430.00762pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)0.0125——pH 7, 37 °CPMID 14672942Open
AKR1C1Homo sapiens4-pregnen-20α-ol-3-one0.1520.0169.5pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5α-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.017 × 10⁻⁴14.3pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5α-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.1520.002757pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5α-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.0730.00237pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5α-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.00130.00330.33pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5α-pregnane-21-ol-3,20-dione0.00930.00127pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5α-pregnane-3,20-dione0.0430.001140pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5α-pregnane-3α,20α-diol0.0379 × 10⁻⁴40pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5α-pregnane-3α,21-diol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.0017——pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5α-pregnane-3α,21-diol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.00370.00261.3pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5β-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.0370.001328pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5β-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.0930.00193pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5β-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.180.003355pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5β-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.0060.00451.3pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5β-pregnan-3α-ol-20-oneKm from secondary plots; reduction of 3α,5β-THP—0.0012—pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5β-pregnane-3,20-dione0.050.001242pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5β-pregnane-3α,20α-dioloxidation direction with 0.25 mM NADP+0.160.0015107pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens5β-pregnane-3α,20α-diolKm from secondary plots—0.0011—pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiens9,10-phenanthrenequinone0.587.3 × 10⁻⁴800pH 7, 37 °CPMID 17950253Open
AKR1C1Homo sapiensNADP+—9 × 10⁻⁴—pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiensNADPH—0.0021—pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapienspregn-4-ene-3,20-dione0.0250.001320pH 7, 25 °CPMID 12604236Open
AKR1C1Homo sapiensprogesterone0.01550.00573.5pH 7, 37 °CPMID 17950253Open
AKR1C1Homo sapienspyridoxalpyridoxal reductase (PLR) activity; PL -> pyridoxine0.0420.3630.115pH 7, 37 °CPMID 41741972Open
AKR1C1Homo sapienspyridoxalpyridoxal dehydrogenase (PLD) activity; 0.2 mM NADP+0.0570.6290.09pH 7, 37 °CPMID 41741972Open
AKR1C2Homo sapiens(S)-1,2,3,4-tetrahydro-1-naphthol0.270.261pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)radiometric time courses; apparent kcat0.0492——pH 7, 37 °CPMID 14672942Open
AKR1C2Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)radiometric assay; [4-14C]DHT; DHT 1.6-41.25 µM—0.0066—pH 7, 37 °CPMID 14672942Open
AKR1C2Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)radiometric assay; [4-14C]DHT; DHT 1.6-41.25 µM—0.011—pH 7, 37 °CPMID 14672942Open
AKR1C2Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)0.05170.004311.937 °CPMID 14672942Open
AKR1C2Homo sapiens4-pregnen-20α-ol-3-one0.00220.00730.33pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5α-dihydrotestosterone0.0630.004613.7pH 7, 37 °CPMID 17950253Open
AKR1C2Homo sapiens5α-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.0085 × 10⁻⁴16pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5α-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.001——pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5α-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.00430.00311.3pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5α-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.00470.0280.17pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5α-pregnane-21-ol-3,20-dione0.00828 × 10⁻⁴10.2pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5α-pregnane-3,20-dione0.0086 × 10⁻⁴11.7pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5α-pregnane-3α,20α-diol0.00320.00181.8pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5α-pregnane-3α,21-diol-20-one0.00220.00680.33pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5β-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.01083 × 10⁻⁴37pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5β-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.0012——pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5β-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.0070.00451.5pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5β-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.00450.00281.7pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5β-pregnane-3,20-dione0.0187 × 10⁻⁴27pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens5β-pregnane-3α,20α-diol0.00370.0013.7pH 7, 25 °CPMID 12604236Open
AKR1C2Homo sapiens9,10-phenanthrenequinone1.830.00111.7 × 10³pH 7, 37 °CPMID 17950253Open
AKR1C2Homo sapienspregn-4-ene-3,20-dione6.7 × 10⁻⁴——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens(S)-1,2,3,4-tetrahydro-1-naphthol0.581.40.5pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)0.0038——pH 7, 37 °CPMID 14672942Open
AKR1C3Homo sapiens4-pregnen-20α-ol-3-one5 × 10⁻⁴——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5α-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.00870.00214.2pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5α-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+1.7 × 10⁻⁴——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5α-pregnan-3α-ol-20-one0.0013——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5α-pregnane-21-ol-3,20-dione0.001——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5α-pregnane-3,20-dione0.001——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5α-pregnane-3α,20α-diol0.001——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5α-pregnane-3α,21-diol-20-one1.7 × 10⁻⁴——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5β-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.0189 × 10⁻⁴20pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5β-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+5 × 10⁻⁴——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5β-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.001——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5β-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.001——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5β-pregnane-3,20-dione0.0032——pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens5β-pregnane-3α,20α-diol0.0280.0271pH 7, 25 °CPMID 12604236Open
AKR1C3Homo sapiens9,10-phenanthrenequinone1.40.0015920pH 7, 37 °CPMID 17950253Open
AKR1C3Homo sapiensandrost-4-ene-3,17-dione0.00270.00660.4pH 7, 37 °CPMID 17950253Open
AKR1C3Homo sapienspyridoxalpyridoxal reductase (PLR) activity; PL -> pyridoxine0.00530.2980.018pH 7, 37 °CPMID 41741972Open
AKR1C3Homo sapienspyridoxalpyridoxal dehydrogenase (PLD) activity; 0.2 mM NADP+0.01271.020.013pH 7, 37 °CPMID 41741972Open
AKR1C4Homo sapiens(S)-1,2,3,4-tetrahydro-1-naphthol0.20.111.8pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)0.0938——pH 7, 37 °CPMID 14672942Open
AKR1C4Homo sapiens4-pregnen-20α-ol-3-one0.00573 × 10⁻⁴18pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5α-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.0220.001120pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5α-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.01072 × 10⁻⁴53pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5α-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.019 × 10⁻⁴11.2pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5α-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.0672 × 10⁻⁴330pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5α-pregnane-21-ol-3,20-dione0.0350.001720pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5α-pregnane-3,20-dione0.026 × 10⁻⁴33pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5α-pregnane-3α,20α-diol0.0672 × 10⁻⁴330pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5α-pregnane-3α,21-diol-20-one0.073 × 10⁻⁴230pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5β-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.0230.001515.5pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5β-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.00833 × 10⁻⁴28pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5β-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH0.01225 × 10⁻⁴25pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5β-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+0.0274 × 10⁻⁴67pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5β-pregnane-3,20-dione0.0577 × 10⁻⁴82pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapiens5β-pregnane-3α,20α-diol0.022 × 10⁻⁴100pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapienspregn-4-ene-3,20-dione8.3 × 10⁻⁴——pH 7, 25 °CPMID 12604236Open
AKR1C4Homo sapienspyridoxal0.0060.3040.02pH 7, 37 °CPMID 41741972Open
AKR1C4 (hydroxysteroid dehydrogenase isoform)Homo sapiens(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenal (all-trans-geranylgeranial)——13PMID 19464995Open
aldo-keto reductase AKR1C1 (human 20α-HSD)Homo sapiens5α-dihydrotestosterone0.01230.00423PMID 19218247Open
aldo-keto reductase AKR1C1 (human 20α-HSD)Homo sapiens5α-dihydrotestosterone-17β-glucuronide0.00880.01610.55PMID 19218247Open
aldo-keto reductase AKR1C1 (human 20α-HSD)Homo sapiens5α-dihydrotestosterone-17β-sulfate0.01250.00522.3PMID 19218247Open
aldo-keto reductase AKR1C1 (human 20α-HSD)Homo sapienstibolone-17β-sulfate0.0320.002512.7PMID 19218247Open
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)Homo sapiens5α-dihydrotestosterone0.0330.002911.3PMID 19218247Open
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)Homo sapiens5α-dihydrotestosterone-17β-glucuronide0.0040.00410.98PMID 19218247Open
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)Homo sapiens5α-dihydrotestosterone-17β-sulfate0.0170.00424PMID 19218247Open
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)Homo sapienstibolone-17β-sulfate0.2020.0012170PMID 19218247Open
aldo-keto reductase AKR1C4 (human type 1 3α-HSD)Homo sapiens5α-dihydrotestosterone0.0513——PMID 19218247Open
aldo-keto reductase AKR1C4 (human type 1 3α-HSD)Homo sapiens5α-dihydrotestosterone-17β-glucuronide0.0547——PMID 19218247Open
aldo-keto reductase AKR1C4 (human type 1 3α-HSD)Homo sapiens5α-dihydrotestosterone-17β-sulfate0.0512——PMID 19218247Open
aldo-keto reductase AKR1C4 (human type 1 3α-HSD)Homo sapienstibolone-17β-sulfate0.025 × 10⁻⁴40PMID 19218247Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens1-Indanone—0.915—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens1-Phenyl-1,2-propanedione—0.06—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens17β-Estradiol—0.016—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens2,3-Heptanedione—0.201—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens2,3-Hexanedione—0.62—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens2,3-Pentanedione—4—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens20α-Hydroxyprogesterone—0.0051—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens3,4-Hexanedione—0.42—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens3β-Hydroxyprogesterone—0.022—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens4-Androsten-3α-ol-17-one—0.019—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens4-Androstene-3,17-dione—0.0046—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens4-Androstene-3α,17β-diol—0.023—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5-Androstene-3β,17β-diol—0.011—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5α-Androstan-3α-ol-17-one—0.0013—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5α-Androstan-3β-ol-17-one—0.0022—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5α-Androstane-3,17-dione—0.012—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5α-Androstane-3α,17β-diol—0.0092—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5α-Androstane-3β,17β-diol—0.0011—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5α-dihydrotestosterone—0.026—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Androstan-3β-ol-17-one—0.036—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Androstane-3,17-dione—0.0052—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Androstane-3β,17β-diol—0.012—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Cholanic acid-3,7-dione—0.0052—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-dihydrotestosterone—0.102—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Pregnan-20β-ol-3-one—7 × 10⁻⁴—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Pregnan-3β-ol-20-one—0.036—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Pregnane-21-ol-3,20-dione—0.0021—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Pregnane-3,20-dione—0.015—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Pregnane-3β,20β-diol—0.014—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiens5β-Pregnane-3β,21-diol-20-one—0.0047—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensDehydrocholic acid—0.029—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensdehydroepiandrosterone—0.011—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensdehydroepiandrosterone sulfate—0.012—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensDehydrolithocholic acid—0.0011—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensDiacetyl—5.1—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensEstrone—7 × 10⁻⁴—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensEthyl pyruvate—1.7—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensIsolithocholic acid—4 × 10⁻⁴—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensLoxoprofen—0.74—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensMethylglyoxal—4.27—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensNADPH—0.0011—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensPhenylglyoxal—0.161—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensProgesterone—0.0034—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensTaurodehydrocholic acid—0.044—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensTestosterone—0.03—pH 7, 37 °CPMID 26920053Open
DHRS11 (dehydrogenase/reductase SDR family member 11)Homo sapiensα-Tetralone—0.178—pH 7, 37 °CPMID 26920053Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus1,2,3,4-tetrahydro-1-naphthol—0.23—pH 10, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus1-acenaphthenol—1.12—pH 10, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus1-indanol—0.75—pH 10, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus2-nitrobenzaldehyde—0.002—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus3-nitrobenzaldehyde—0.058—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus4-benzoylpyridine—0.03—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus4-nitroacetophenone—0.015—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus4-nitrobenzaldehyde—0.024—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus5alpha-dihydrotestosterone—0.009—pH 10, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculus5beta-dihydrotestosterone—0.007—pH 10, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusaetiocholanolone—0.002—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusandrost-4-ene-3,17-dione—0.004—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusandrosterone—0.009—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculuscyclohex-2-en-1-ol—0.169—pH 10, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusdiacetyl—0.014—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusepiandrosterone—0.008—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusmenadione—0.023—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusn-butyraldehyde—0.308—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusNADP—0.015—pH 10, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusNADPH—0.001—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusoestradiol-17beta—0.014—pH 10, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculusoestrone-3-sulfate—0.009—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculuspyridine-3-aldehyde—0.103—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculuspyridine-4-aldehyde—0.004—pH 6, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculustestosterone—0.019—pH 10, 25 °CPMID 3276326Open
dihydrodiol dehydrogenase DD1 (17beta-hydroxysteroid dehydrogenase)Mus musculustrans-1,2-dihydroxy-3,5-cyclohexadiene—0.11—pH 10, 25 °CPMID 3276326Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiens1-methylestra-1,3,5(10),6-tetraene-3,17beta-diol—0.0085—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiens1-methylestra-1,3,5(10)-triene-3,17beta-diol—0.015—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiens3-acetoxyestra-1,3,5(10),6,8-pentaene-11,17-dione—0.012—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiens3-hydroxyestra-1,3,5(10),6,8-pentaen-17-one—0.02—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiens3-hydroxyestra-1,3,5(10),7-tetraen-17-one—0.013—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiens3-hydroxyestra-1,3,5(10)-trien-17-one—0.022—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiens3-hydroxyestra-1,3,5(10)-triene-7,17-dione—0.047—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiens3-methoxyestra-1,3,5(10)-trien-17beta-ol—0.03—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiens4-methylestra-1,3,5(10)-triene-1,17beta-diol—0.032—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiensestra-1,3,5(10)-triene-3,17beta-diol—0.022—37 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiensestra-1,3,5(10)-triene-3,17beta-diolCary recording spectrophotometer (DPNH formation)—0.003—23 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiensestra-1,3,5(10)-triene-3,17beta-diolCary recording spectrophotometer (DPNH formation)—0.0034—23 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiensestra-1,3,5(10)-triene-3,17beta-diolCary recording spectrophotometer (DPNH formation)—0.0035—23 °CPMID 14413943Open
estradiol-17beta dehydrogenase (DPN-specific)Homo sapiensestra-1,3,5(10)-triene-3,17beta-diolabout 23 °C—0.0045—23 °CPMID 14413943Open
human type 3 3α-hydroxysteroid dehydrogenase (h3α-HSD3)variant Y24AHomo sapiensandrost-4-ene-3,17-dione17α-HSD activity (17α-reduction of Δ4)3.3 × 10⁻⁴0.020940.017pH 7.3, 37 °CPMID 17442338Open
human type 3 3α-hydroxysteroid dehydrogenase (h3α-HSD3)variant Y24AHomo sapiensandrost-4-ene-3,17-dione17β-HSD activity (17β-reduction of Δ4 to testosterone)0.02150.029570.73pH 7.3, 37 °CPMID 17442338Open
Ke 6 (17beta-hydroxysteroid dehydrogenase)Mus musculus17beta-estradiol—1.1 × 10⁻⁴—PMID 9712896Open
Ke 6 (17beta-hydroxysteroid dehydrogenase)Mus musculus5alpha-dihydrotestosterone—3.6 × 10⁻⁴—PMID 9712896Open
Ke 6 (17beta-hydroxysteroid dehydrogenase)Mus musculusestrone—3.68 × 10⁻⁴—PMID 9712896Open
Ke 6 (17beta-hydroxysteroid dehydrogenase)Mus musculustestosterone—4.22 × 10⁻⁴—PMID 9712896Open
RoDH (retinol dehydrogenase), humanHomo sapiens4-androsten-17beta-ol-3-one—0.0033—pH 7.5, 37 °CPMID 9188497Open
RoDH (retinol dehydrogenase), humanHomo sapiens5alpha-androstan-17beta-ol-3-one—1 × 10⁻⁴—pH 7.5, 37 °CPMID 9188497Open
RoDH (retinol dehydrogenase), humanHomo sapiens5alpha-androstan-3alpha-ol-17-one—1 × 10⁻⁴—pH 7.5, 37 °CPMID 9188497Open
RoDH (retinol dehydrogenase), humanHomo sapiens5alpha-androstane-3alpha,17beta-diol—1 × 10⁻⁴—pH 7.5, 37 °CPMID 9188497Open