CatLogenzyme kinetics catalog

Values CatLog read from this paper

Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization…

PMID 12917011doi:10.1042/bj20030877Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 19 records (47 values) from this paper: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully), 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) from Drosophila melanogaster, Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.35, EC 1.1.1.53, EC 1.1.1.62, EC 1.1.1.159, EC 1.1.1.178, EC 1.1.1.239

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens11-dehydrocorticosterone5 × 10⁻⁴0.00170.3pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens3-hydroxybutyryl-CoA4.830.085257pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens3α,7α-dihydroxy-5β-cholan-24-oic acid5.7 × 10⁻⁴0.03640.017pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens3β,7β-dihydroxy-5β-cholan-24-oic acid9 × 10⁻⁴0.2190.0033pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens5α-androstan-3α-ol-17-one6.7 × 10⁻⁴0.0410.017pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiens5α-pregnan-20β-ol-3-one0.00420.0050.88pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiensacetoacetyl-CoA23.80.0257927pH 7, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiensNAD+—0.0423—pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB)Homo sapiensNADH—0.0306—pH 7, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogaster17β-estradiol0.00870.01110.8pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogaster3-hydroxybutyryl-CoA1.1330.10111.2pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogaster3β,7β-dihydroxy-5β-cholan-24-oic acid2.3 × 10⁻⁴0.0030.083pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogaster5α-androstan-17β-ol-3-one0.0770.01236.2pH 6.4, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogaster5α-androstan-3α-ol-17-one0.210.03735.5pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogaster5α-pregnan-20β-ol-3-one0.001270.0090.13pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogasteracetoacetyl-CoA27.670.0337837pH 6.4, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogasterNAD+beta-hydroxybutyryl-CoA; cosubstrate β-Hydroxybutyryl-CoA—0.0644—pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogasterNAD+androsterone; cosubstrate Androsterone—0.124—pH 9.3, 25 °COpen
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, Scully)Drosophila melanogasterNADH—0.0325—pH 6.4, 25 °COpen