EC 1.1.1.178: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
OxidoreductasesOpen in Browse
CatLog read 9 records for EC 1.1.1.178 from 1 paper, for 1 organism. Names in these papers: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 6 records for EC 1.1.1.178 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.178 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization… | Homo sapiens | 9 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) | Homo sapiens | 11-dehydrocorticosterone | 5 × 10⁻⁴ | 0.0017 | 0.3 | pH 9.3, 25 °C | PMID 12917011 | Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 11-dehydrocorticosterone |
| 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) | Homo sapiens | 3-hydroxybutyryl-CoA | 4.83 | 0.0852 | 57 | pH 9.3, 25 °C | PMID 12917011 | Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 3-hydroxybutyryl-CoA |
| 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) | Homo sapiens | 3α,7α-dihydroxy-5β-cholan-24-oic acid | 5.7 × 10⁻⁴ | 0.0364 | 0.017 | pH 9.3, 25 °C | PMID 12917011 | Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 3α,7α-dihydroxy-5β-cholan-24-oic acid |
| 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) | Homo sapiens | 3β,7β-dihydroxy-5β-cholan-24-oic acid | 9 × 10⁻⁴ | 0.219 | 0.0033 | pH 9.3, 25 °C | PMID 12917011 | Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 3β,7β-dihydroxy-5β-cholan-24-oic acid |
| 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) | Homo sapiens | 5α-androstan-3α-ol-17-one | 6.7 × 10⁻⁴ | 0.041 | 0.017 | pH 9.3, 25 °C | PMID 12917011 | Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 5α-androstan-3α-ol-17-one |
| 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) | Homo sapiens | 5α-pregnan-20β-ol-3-one | 0.0042 | 0.005 | 0.88 | pH 9.3, 25 °C | PMID 12917011 | Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), 5α-pregnan-20β-ol-3-one |
| 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) | Homo sapiens | acetoacetyl-CoA | 23.8 | 0.0257 | 927 | pH 7, 25 °C | PMID 12917011 | Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), acetoacetyl-CoA |
| 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) | Homo sapiens | NAD+ | — | 0.0423 | — | pH 9.3, 25 °C | PMID 12917011 | Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), NAD+ |
| 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB) | Homo sapiens | NADH | — | 0.0306 | — | pH 7, 25 °C | PMID 12917011 | Open record: 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10, ERAB), NADH |