Values CatLog read from this paper
Substrate specificity and inhibitor sensitivity of rabbit 20α-hydroxysteroid dehydrogenase
PMID 23995665doi:10.1248/bpb.b13-00342Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 64 records (191 values) from this paper: 20α-hydroxysteroid dehydrogenase (AKR1C5), 20α-hydroxysteroid dehydrogenase (AKR1C1) from Oryctolagus cuniculus, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 1 kcat/Km value marked “calc.” from kcat and Km; no printed kcat/Km was read for that record.
EC 1.1.1.51, EC 1.1.1.53, EC 1.1.1.62, EC 1.1.1.112, EC 1.1.1.149, EC 1.1.1.189, EC 1.1.1.209, EC 1.1.1.210, EC 1.1.1.270, EC 1.1.1.357, EC 1.3.1.20
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 20α-hydroxysteroid dehydrogenase (AKR1C1) | Homo sapiens | β-Ionol | 0.053 | 0.0012 | 44 calc. | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C1), β-Ionol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | (S)-1-Indanol | 0.2 | 0.131 | 1.53 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), (S)-1-Indanol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | (S)-1-Tetralol | 0.22 | 0.112 | 2 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), (S)-1-Tetralol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 1-Hexanal | 0.043 | 0.0076 | 5.7 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 1-Hexanal |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 1-Nonanal | 0.032 | 9 × 10⁻⁴ | 35 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 1-Nonanal |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 17β-Estradiol | 0.0112 | 0.0013 | 8.7 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 17β-Estradiol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 2-tert-butyl-1,4-benzoquinone | 0.18 | 0.001 | 180 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 2-tert-butyl-1,4-benzoquinone |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 20α-Hydroxyprogesterone | 0.048 | 0.0022 | 22 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 20α-Hydroxyprogesterone |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 3-Deoxyglucosone | 0.18 | 1.4 | 0.13 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 3-Deoxyglucosone |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 4-Androstene-3,17-dione | 0.043 | 0.001 | 43 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 4-Androstene-3,17-dione |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 4-Chromanol | 0.068 | 0.152 | 0.45 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 4-Chromanol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 4-Hydroxy-2-nonenal | 0.0087 | 0.0053 | 1.63 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 4-Hydroxy-2-nonenal |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 4-Nitroacetophenone | 0.112 | 0.0012 | 93 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 4-Nitroacetophenone |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 4-Oxo-2-hexenal | 0.0115 | 0.0059 | 1.8 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 4-Oxo-2-hexenal |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 4-Oxo-2-nonenal | 0.112 | 0.0018 | 62 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 4-Oxo-2-nonenal |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 4-Pregnen-3α-ol-20-one | 0.032 | 0.001 | 32 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 4-Pregnen-3α-ol-20-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5-Androstene-3β,17β-diol | 0.1 | 0.0031 | 32 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5-Androstene-3β,17β-diol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-androstan-17β-ol-3-onereduction; 0.1 mM NADPH; NADPH absorbance; cosubstrate NADPH | 0.025 | 0.0034 | 7.3 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-androstan-17β-ol-3-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-androstan-17β-ol-3-oneoxidation; 0.25 mM NADP+; NADPH fluorescence | 0.047 | 0.018 | 2.7 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-androstan-17β-ol-3-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Androstan-3α-ol-17-one | 0.085 | 0.0041 | 20 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Androstan-3α-ol-17-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Androstan-3β-ol-17-one | 0.083 | 0.006 | 13.8 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Androstan-3β-ol-17-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Androstane-3α,17β-diol | 0.27 | 0.0042 | 63 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Androstane-3α,17β-diol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Androstane-3β,17β-diol | 0.032 | 0.0022 | 14.3 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Androstane-3β,17β-diol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Pregnan-20α-ol-3-onereduction; 0.1 mM NADPH; NADPH absorbance; cosubstrate NADPH | 0.077 | 0.0059 | 13 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Pregnan-20α-ol-3-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Pregnan-20α-ol-3-oneoxidation; 0.25 mM NADP+; NADPH fluorescence | 0.158 | 0.011 | 14.3 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Pregnan-20α-ol-3-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Pregnan-3α-ol-20-one | 0.032 | 0.0013 | 25 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Pregnan-3α-ol-20-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Pregnane-3,20-dione | 0.018 | 5 × 10⁻⁴ | 37 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Pregnane-3,20-dione |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Pregnane-3α,20α-diol | 0.025 | 8 × 10⁻⁴ | 30 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Pregnane-3α,20α-diol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5α-Pregnane-3α,21-diol-20-one | 0.018 | 0.0062 | 3 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5α-Pregnane-3α,21-diol-20-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Androstan-17β-ol-3-one | 0.153 | 0.0062 | 25 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Androstan-17β-ol-3-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Androstan-3α-ol-17-one | 0.067 | 0.0017 | 40 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Androstan-3α-ol-17-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Androstan-3β-ol-17-one | 0.045 | 0.0028 | 16 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Androstan-3β-ol-17-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Androstane-3α,17β-diol | 0.25 | 0.0014 | 180 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Androstane-3α,17β-diol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Androstane-3β,17β-diol | 0.033 | 0.0025 | 13.3 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Androstane-3β,17β-diol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Pregnan-20α-ol-3-one | 0.153 | 0.0057 | 27 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Pregnan-20α-ol-3-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Pregnan-3α-ol-20-one | 0.03 | 0.001 | 30 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Pregnan-3α-ol-20-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Pregnane-3,20-dione | 0.028 | 0.001 | 28 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Pregnane-3,20-dione |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Pregnane-3α,20α-diol | 0.28 | 0.0078 | 37 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Pregnane-3α,20α-diol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 5β-Pregnane-3α,21-diol-20-one | 0.017 | 0.0026 | 6.3 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 5β-Pregnane-3α,21-diol-20-one |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione | 0.17 | 0.002 | 83 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | 7α-hydroxydehydroepiandrosterone | 0.043 | 0.0029 | 15 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), 7α-hydroxydehydroepiandrosterone |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Acetoin | 0.097 | 0.162 | 1.33 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Acetoin |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Acrolein | 0.035 | 0.014 | 2.5 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Acrolein |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | all-trans-Retinal | 0.0085 | 0.0089 | 0.95 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), all-trans-Retinal |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Befunolol | 0.117 | 0.034 | 13.2 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Befunolol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | dehydroepiandrosterone (5-androsten-3β-ol-17-one) | 0.155 | 0.006 | 27 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), dehydroepiandrosterone (5-androsten-3β-ol-17-one) |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | dehydroepiandrosterone 3-sulfate | 0.08 | 0.0042 | 18 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), dehydroepiandrosterone 3-sulfate |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Diacetyl | 0.158 | 0.019 | 8.3 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Diacetyl |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Estrone | 0.017 | 0.0011 | 15.2 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Estrone |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Estrone-3-sulfate | 0.098 | 0.0067 | 14.7 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Estrone-3-sulfate |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Geraniol | 0.033 | 0.18 | 0.18 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Geraniol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Isatin | 0.137 | 6 × 10⁻⁴ | 230 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Isatin |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Isocaproaldehyde | 0.023 | 0.068 | 0.35 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Isocaproaldehyde |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Ketotifen | 0.02 | 0.111 | 0.18 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Ketotifen |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Menadione | 0.125 | 0.018 | 2 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Menadione |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Methylglyoxal | 0.12 | 0.088 | 1.37 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Methylglyoxal |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Progesterone | 0.027 | 6 × 10⁻⁴ | 45 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Progesterone |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Pyridine-3-aldehyde | 0.132 | 0.061 | 2.2 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Pyridine-3-aldehyde |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | Testosterone | 0.057 | 0.013 | 4.3 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), Testosterone |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | trans-2-Hexenal | 0.025 | 0.0074 | 3.3 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), trans-2-Hexenal |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | trans-2-Nonenal | 0.02 | 0.0055 | 3.7 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), trans-2-Nonenal |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | trans-Benzene dihydrodiol | 0.108 | 0.26 | 0.42 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), trans-Benzene dihydrodiol |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | α-Tetralone | 0.053 | 0.053 | 1 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), α-Tetralone |
| 20α-hydroxysteroid dehydrogenase (AKR1C5) | Oryctolagus cuniculus | β-Ionol | 0.23 | 0.018 | 10.2 | pH 7.4, 25 °C | Open record: 20α-hydroxysteroid dehydrogenase (AKR1C5), β-Ionol |