EC 1.3.1.20: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 446 records for EC 1.3.1.20 from 22 papers, for 10 organisms. Names in these papers: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), dimeric dihydrodiol dehydrogenase, dimeric dihydrodiol dehydrogenase (DD), AKR1C1 and 36 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 85 records for EC 1.3.1.20 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.3.1.20 in Browse.

Papers

Papers with records for EC 1.3.1.20
Paper	Organisms	Records
Molecular characterization of two monkey dihydrodiol dehydrogenases	Homo sapiens, Macaca fascicularis and 1 more	96
Kinetic alteration of a human dihydrodiol/3alpha-hydroxysteroid dehydrogenase isoenzyme, AKR1C4, by replacement of histidine-216 with tyrosine or phenylalanine	Homo sapiens	77
Identity of dimeric dihydrodiol dehydrogenase as NADP(+)-dependent D-xylose dehydrogenase in pig liver	Canis lupus familiaris, Macaca fuscata (Japanese monkey) and 2 more	44
Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone	Homo sapiens	39
Dihydrodiol dehydrogenases in guinea pig liver	guinea pig	34
Purification and characterization of dimeric dihydrodiol dehydrogenase from dog liver	Canis lupus familiaris	28
Dihydrodiol dehydrogenase activities of rabbit liver are associated with hydroxysteroid dehydrogenases and aldo-keto reductases	Oryctolagus cuniculus	21
Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells	Homo sapiens	18
Enzymatic characterization of a novel bovine liver dihydrodiol dehydrogenase--reaction mechanism and bile acid dehydrogenase activity	Bos taurus	15
Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite…	Homo sapiens	14
Roles of His-79 and Tyr-180 of D-xylose/dihydrodiol dehydrogenase in catalytic function	Macaca fuscata (Japanese monkey)	12
Dimeric dihydrodiol dehydrogenase in monkey kidney. Substrate specificity, stereospecificity of hydrogen transfer, and distribution	Macaca fuscata (Japanese monkey)	10
Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism	Homo sapiens	8
Sequence of the cDNA of a human dihydrodiol dehydrogenase isoform (AKR1C2) and tissue distribution of its mRNA	Homo sapiens	6
Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone…	Homo sapiens	5
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target…	Homo sapiens	4
Factorizing the role of a critical leucine residue in the binding of substrate to human 20alpha-hydroxysteroid dehydrogenase (AKR1C1): molecular modeling and kinetic studies of the Leu308Val mutant…	Homo sapiens	4
Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity	Homo sapiens	4
Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate…	Homo sapiens	2
Mouse liver dihydrodiol dehydrogenases. Identity of the predominant and a minor form with 17 beta-hydroxysteroid dehydrogenase and aldehyde reductase	Mus musculus	2
A new branch of mammalian vitamin B₆ metabolism: AKR1C-mediated conversion of pyridoxal to pyridoxine and 4-pyridoxolactone	Homo sapiens	2
Substrate specificity and inhibitor sensitivity of rabbit 20α-hydroxysteroid dehydrogenase	Homo sapiens	1

Records

Records for EC 1.3.1.20 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
20α-hydroxysteroid dehydrogenase (AKR1C1)	Homo sapiens	β-Ionol	0.053	0.0012	44 calc.	pH 7.4, 25 °C	PMID 23995665	Open record: 20α-hydroxysteroid dehydrogenase (AKR1C1), β-Ionol
20α-hydroxysteroid dehydrogenase (AKR1C1)variant L308A	Homo sapiens	(S)-1,2,3,4-tetrahydronaphthalen-1-ol	—	0.47	0.83	pH 7.4, 25 °C	PMID 20656485	Open record: 20α-hydroxysteroid dehydrogenase (AKR1C1) variant L308A, (S)-1,2,3,4-tetrahydronaphthalen-1-ol
20α-hydroxysteroid dehydrogenase (AKR1C1)variant L308V	Homo sapiens	(S)-1,2,3,4-tetrahydronaphthalen-1-ol	—	0.016	13	pH 7.4, 25 °C	PMID 20656485	Open record: 20α-hydroxysteroid dehydrogenase (AKR1C1) variant L308V, (S)-1,2,3,4-tetrahydronaphthalen-1-ol
20α-hydroxysteroid dehydrogenase (AKR1C1)variant L308V	Homo sapiens	5α-pregnane-3α,20α-diol	—	4 × 10⁻⁴	270	pH 7.4, 25 °C	PMID 20656485	Open record: 20α-hydroxysteroid dehydrogenase (AKR1C1) variant L308V, 5α-pregnane-3α,20α-diol
20α-hydroxysteroid dehydrogenase (AKR1C1)variant L308V	Homo sapiens	5β-pregnan-3α-ol-20-one	—	0.0062	27	pH 7.4, 25 °C	PMID 20656485	Open record: 20α-hydroxysteroid dehydrogenase (AKR1C1) variant L308V, 5β-pregnan-3α-ol-20-one
3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)	Homo sapiens	5α-dihydrotestosterone	0.0612	0.00218	28	pH 7.4, 37 °C	PMID 24434280	Open record: 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2), 5α-dihydrotestosterone
3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)	Homo sapiens	progesterone	0.0035	8.4 × 10⁻⁴	4.2	pH 7.4, 37 °C	PMID 24434280	Open record: 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2), progesterone
3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)variant V54L	Homo sapiens	5α-dihydrotestosterone	0.1153	0.07103	1.7	pH 7.4, 37 °C	PMID 24434280	Open record: 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2) variant V54L, 5α-dihydrotestosterone
3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)variant V54L	Homo sapiens	progesterone	0.0392	0.00213	18.3	pH 7.4, 37 °C	PMID 24434280	Open record: 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2) variant V54L, progesterone
AKR1C1	Homo sapiens	(S)-1,2,3,4-tetrahydro-1-naphthol	0.43	0.007	62	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, (S)-1,2,3,4-tetrahydro-1-naphthol
AKR1C1	Homo sapiens	17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)	0.0125	—	—	pH 7, 37 °C	PMID 14672942	Open record: AKR1C1, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)
AKR1C1	Homo sapiens	4-pregnen-20α-ol-3-one	0.152	0.016	9.5	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 4-pregnen-20α-ol-3-one
AKR1C1	Homo sapiens	5α-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.01	7 × 10⁻⁴	14.3	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5α-pregnan-20α-ol-3-one
AKR1C1	Homo sapiens	5α-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.152	0.0027	57	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5α-pregnan-20α-ol-3-one
AKR1C1	Homo sapiens	5α-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.073	0.002	37	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5α-pregnan-3α-ol-20-one
AKR1C1	Homo sapiens	5α-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.0013	0.0033	0.33	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5α-pregnan-3α-ol-20-one
AKR1C1	Homo sapiens	5α-pregnane-21-ol-3,20-dione	0.0093	0.0012	7	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5α-pregnane-21-ol-3,20-dione
AKR1C1	Homo sapiens	5α-pregnane-3,20-dione	0.043	0.0011	40	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5α-pregnane-3,20-dione
AKR1C1	Homo sapiens	5α-pregnane-3α,20α-diol	0.037	9 × 10⁻⁴	40	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5α-pregnane-3α,20α-diol
AKR1C1	Homo sapiens	5α-pregnane-3α,21-diol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.0017	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5α-pregnane-3α,21-diol-20-one
AKR1C1	Homo sapiens	5α-pregnane-3α,21-diol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.0037	0.0026	1.3	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5α-pregnane-3α,21-diol-20-one
AKR1C1	Homo sapiens	5β-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.037	0.0013	28	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5β-pregnan-20α-ol-3-one
AKR1C1	Homo sapiens	5β-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.093	0.001	93	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5β-pregnan-20α-ol-3-one
AKR1C1	Homo sapiens	5β-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.18	0.0033	55	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5β-pregnan-3α-ol-20-one
AKR1C1	Homo sapiens	5β-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.006	0.0045	1.3	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5β-pregnan-3α-ol-20-one
AKR1C1	Homo sapiens	5β-pregnan-3α-ol-20-oneKm from secondary plots; reduction of 3α,5β-THP	—	0.0012	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5β-pregnan-3α-ol-20-one
AKR1C1	Homo sapiens	5β-pregnane-3,20-dione	0.05	0.0012	42	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5β-pregnane-3,20-dione
AKR1C1	Homo sapiens	5β-pregnane-3α,20α-dioloxidation direction with 0.25 mM NADP+	0.16	0.0015	107	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5β-pregnane-3α,20α-diol
AKR1C1	Homo sapiens	5β-pregnane-3α,20α-diolKm from secondary plots	—	0.0011	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, 5β-pregnane-3α,20α-diol
AKR1C1	Homo sapiens	9,10-phenanthrenequinone	0.58	7.3 × 10⁻⁴	800	pH 7, 37 °C	PMID 17950253	Open record: AKR1C1, 9,10-phenanthrenequinone
AKR1C1	Homo sapiens	NADP+	—	9 × 10⁻⁴	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, NADP+
AKR1C1	Homo sapiens	NADPH	—	0.0021	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, NADPH
AKR1C1	Homo sapiens	pregn-4-ene-3,20-dione	0.025	0.0013	20	pH 7, 25 °C	PMID 12604236	Open record: AKR1C1, pregn-4-ene-3,20-dione
AKR1C1	Homo sapiens	progesterone	0.0155	0.0057	3.5	pH 7, 37 °C	PMID 17950253	Open record: AKR1C1, progesterone
AKR1C1	Homo sapiens	pyridoxalpyridoxal reductase (PLR) activity; PL -> pyridoxine	0.042	0.363	0.115	pH 7, 37 °C	PMID 41741972	Open record: AKR1C1, pyridoxal
AKR1C1	Homo sapiens	pyridoxalpyridoxal dehydrogenase (PLD) activity; 0.2 mM NADP+	0.057	0.629	0.09	pH 7, 37 °C	PMID 41741972	Open record: AKR1C1, pyridoxal
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	(R)-1,2,3,4-tetrahydronaphthalen-1-ol	0.018	0.18	0.17	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), (R)-1,2,3,4-tetrahydronaphthalen-1-ol
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	4-Chromanol	0.65	0.104	6.3	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 4-Chromanol
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	4-Chromanone	0.12	0.0031	38	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 4-Chromanone
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	4-Pregnen-20α-ol-3-one	0.152	0.016	9.3	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 4-Pregnen-20α-ol-3-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Androstan-17β-ol-3-one	0.018	0.012	1.5	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Androstan-17β-ol-3-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-androstan-17β-ol-3-one	6.7 × 10⁻⁴	—	—	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-androstan-17β-ol-3-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Androstan-3α-ol-17-one	0.0035	0.015	0.17	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Androstan-3α-ol-17-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Androstane-3,17-dione	0.027	0.0033	8	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Androstane-3,17-dione
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Androstane-3α,17β-diol	0.005	0.018	0.33	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Androstane-3α,17β-diol
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Pregnan-20α-ol-3-one	0.152	0.0027	57	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Pregnan-20α-ol-3-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Pregnan-20α-ol-3-one	0.01	7 × 10⁻⁴	14.3	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Pregnan-20α-ol-3-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Pregnan-3α-ol-20-one	0.0013	0.0033	0.33	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Pregnan-3α-ol-20-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Pregnane-21-ol-3,20-dione	0.0083	0.0012	7	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Pregnane-21-ol-3,20-dione
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Pregnane-3,20-dione	0.05	0.0011	45	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Pregnane-3,20-dione
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5α-Pregnane-3α,21-diol-20-one	0.0037	0.0026	1.5	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5α-Pregnane-3α,21-diol-20-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5β-Pregnan-20α-ol-3-one	0.093	0.001	93	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5β-Pregnan-20α-ol-3-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5β-Pregnan-20α-ol-3-one	0.037	0.0013	28	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5β-Pregnan-20α-ol-3-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	5β-Pregnan-3α-ol-20-one	0.0063	0.0045	1.5	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), 5β-Pregnan-3α-ol-20-one
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	Befunolol	0.1	0.041	2.5	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), Befunolol
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	Progesterone	0.025	—	—	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), Progesterone
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	Prostaglandin D2	0.017	0.012	1.3	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), Prostaglandin D2
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	S-(+)-1,2,3,4-tetrahydronaphth-1-ol	0.43	0.0074	62	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), S-(+)-1,2,3,4-tetrahydronaphth-1-ol
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	S-Indan-1-ol	0.42	0.05	8.3	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), S-Indan-1-ol
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	trans-Benzene dihydrodiol	0.145	0.82	0.17	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), trans-Benzene dihydrodiol
AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase)	Homo sapiens	α-Tetralone	0.05	0.0013	38	pH 7, 25 °C	PMID 15618685	Open record: AKR1C1 (human 3(20)α-hydroxysteroid dehydrogenase), α-Tetralone
AKR1C2	Homo sapiens	(S)-1,2,3,4-tetrahydro-1-naphthol	0.27	0.26	1	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, (S)-1,2,3,4-tetrahydro-1-naphthol
AKR1C2	Homo sapiens	17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)radiometric time courses; apparent kcat	0.0492	—	—	pH 7, 37 °C	PMID 14672942	Open record: AKR1C2, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)
AKR1C2	Homo sapiens	17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)radiometric assay; [4-14C]DHT; DHT 1.6-41.25 µM	—	0.0066	—	pH 7, 37 °C	PMID 14672942	Open record: AKR1C2, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)
AKR1C2	Homo sapiens	17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)radiometric assay; [4-14C]DHT; DHT 1.6-41.25 µM	—	0.011	—	pH 7, 37 °C	PMID 14672942	Open record: AKR1C2, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)
AKR1C2	Homo sapiens	17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)	0.0517	0.0043	11.9	37 °C	PMID 14672942	Open record: AKR1C2, 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)
AKR1C2	Homo sapiens	4-pregnen-20α-ol-3-one	0.0022	0.0073	0.33	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 4-pregnen-20α-ol-3-one
AKR1C2	Homo sapiens	5α-dihydrotestosterone	0.063	0.0046	13.7	pH 7, 37 °C	PMID 17950253	Open record: AKR1C2, 5α-dihydrotestosterone
AKR1C2	Homo sapiens	5α-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.008	5 × 10⁻⁴	16	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5α-pregnan-20α-ol-3-one
AKR1C2	Homo sapiens	5α-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.001	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5α-pregnan-20α-ol-3-one
AKR1C2	Homo sapiens	5α-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.0043	0.0031	1.3	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5α-pregnan-3α-ol-20-one
AKR1C2	Homo sapiens	5α-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.0047	0.028	0.17	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5α-pregnan-3α-ol-20-one
AKR1C2	Homo sapiens	5α-pregnane-21-ol-3,20-dione	0.0082	8 × 10⁻⁴	10.2	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5α-pregnane-21-ol-3,20-dione
AKR1C2	Homo sapiens	5α-pregnane-3,20-dione	0.008	6 × 10⁻⁴	11.7	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5α-pregnane-3,20-dione
AKR1C2	Homo sapiens	5α-pregnane-3α,20α-diol	0.0032	0.0018	1.8	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5α-pregnane-3α,20α-diol
AKR1C2	Homo sapiens	5α-pregnane-3α,21-diol-20-one	0.0022	0.0068	0.33	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5α-pregnane-3α,21-diol-20-one
AKR1C2	Homo sapiens	5β-pregnan-20α-ol-3-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.0108	3 × 10⁻⁴	37	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5β-pregnan-20α-ol-3-one
AKR1C2	Homo sapiens	5β-pregnan-20α-ol-3-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.0012	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5β-pregnan-20α-ol-3-one
AKR1C2	Homo sapiens	5β-pregnan-3α-ol-20-onereduction direction with 0.1 mM NADPH; cosubstrate NADPH	0.007	0.0045	1.5	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5β-pregnan-3α-ol-20-one
AKR1C2	Homo sapiens	5β-pregnan-3α-ol-20-oneoxidation direction with 0.25 mM NADP+; cosubstrate NADP+	0.0045	0.0028	1.7	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5β-pregnan-3α-ol-20-one
AKR1C2	Homo sapiens	5β-pregnane-3,20-dione	0.018	7 × 10⁻⁴	27	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5β-pregnane-3,20-dione
AKR1C2	Homo sapiens	5β-pregnane-3α,20α-diol	0.0037	0.001	3.7	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, 5β-pregnane-3α,20α-diol
AKR1C2	Homo sapiens	9,10-phenanthrenequinone	1.83	0.0011	1.7 × 10³	pH 7, 37 °C	PMID 17950253	Open record: AKR1C2, 9,10-phenanthrenequinone
AKR1C2	Homo sapiens	pregn-4-ene-3,20-dione	6.7 × 10⁻⁴	—	—	pH 7, 25 °C	PMID 12604236	Open record: AKR1C2, pregn-4-ene-3,20-dione
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	(R)-1,2,3,4-tetrahydronaphthalen-1-ol	0.18	0.16	1.2	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), (R)-1,2,3,4-tetrahydronaphthalen-1-ol
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	4-Chromanol	0.103	0.65	1.7	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 4-Chromanol
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	4-Pregnen-20α-ol-3-one	0.0057	3 × 10⁻⁴	18	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 4-Pregnen-20α-ol-3-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Androstan-17β-ol-3-one	0.023	7 × 10⁻⁴	33	pH 7, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Androstan-17β-ol-3-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Androstan-3α-ol-17-one	0.043	5 × 10⁻⁴	87	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Androstan-3α-ol-17-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Androstane-3,17-dione	0.03	0.0014	22	pH 7, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Androstane-3,17-dione
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Androstane-3α,17β-diol	0.087	8 × 10⁻⁴	103	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Androstane-3α,17β-diol
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Pregnan-20α-ol-3-one	0.0107	2 × 10⁻⁴	53	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Pregnan-20α-ol-3-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Pregnan-20α-ol-3-one	0.018	0.0011	17	pH 7, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Pregnan-20α-ol-3-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Pregnan-3α-ol-20-one	0.067	3 × 10⁻⁴	220	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Pregnan-3α-ol-20-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Pregnan-3α-ol-20-one	0.01	9 × 10⁻⁴	11.2	pH 7, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Pregnan-3α-ol-20-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Pregnane-21-ol-3,20-dione	0.035	0.0017	20	pH 7, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Pregnane-21-ol-3,20-dione
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Pregnane-3,20-dione	0.02	6 × 10⁻⁴	33	pH 7, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Pregnane-3,20-dione
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5α-Pregnane-3α,21-diol-20-one	0.07	3 × 10⁻⁴	230	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5α-Pregnane-3α,21-diol-20-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5β-Pregnan-20α-ol-3-one	0.01	3 × 10⁻⁴	33	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5β-Pregnan-20α-ol-3-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5β-Pregnan-20α-ol-3-one	0.023	0.0012	20	pH 7, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5β-Pregnan-20α-ol-3-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5β-Pregnan-3α-ol-20-one	0.027	4 × 10⁻⁴	67	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5β-Pregnan-3α-ol-20-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	5β-Pregnan-3α-ol-20-one	0.0122	5 × 10⁻⁴	25	pH 7, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), 5β-Pregnan-3α-ol-20-one
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	S-(+)-1,2,3,4-tetrahydronaphth-1-ol	0.162	0.105	1.5	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), S-(+)-1,2,3,4-tetrahydronaphth-1-ol
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	S-Indan-1-ol	0.102	0.146	0.67	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), S-Indan-1-ol
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	trans-Benzene dihydrodiol	0.01	0.022	0.5	pH 7.4, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), trans-Benzene dihydrodiol
AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1)	Homo sapiens	α-Tetralone	0.028	0.035	0.83	pH 7, 25 °C	PMID 15618685	Open record: AKR1C4 (human 3α-hydroxysteroid dehydrogenase type 1), α-Tetralone
aldo-keto reductase AKR1C1 (human 20α-HSD)	Homo sapiens	5α-dihydrotestosterone	0.0123	0.0042	3		PMID 19218247	Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), 5α-dihydrotestosterone
aldo-keto reductase AKR1C1 (human 20α-HSD)	Homo sapiens	5α-dihydrotestosterone-17β-glucuronide	0.0088	0.0161	0.55		PMID 19218247	Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), 5α-dihydrotestosterone-17β-glucuronide
aldo-keto reductase AKR1C1 (human 20α-HSD)	Homo sapiens	5α-dihydrotestosterone-17β-sulfate	0.0125	0.0052	2.3		PMID 19218247	Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), 5α-dihydrotestosterone-17β-sulfate
aldo-keto reductase AKR1C1 (human 20α-HSD)	Homo sapiens	tibolone-17β-sulfate	0.032	0.0025	12.7		PMID 19218247	Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), tibolone-17β-sulfate
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)	Homo sapiens	5α-dihydrotestosterone	0.033	0.0029	11.3		PMID 19218247	Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), 5α-dihydrotestosterone
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)	Homo sapiens	5α-dihydrotestosterone-17β-glucuronide	0.004	0.0041	0.98		PMID 19218247	Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), 5α-dihydrotestosterone-17β-glucuronide
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)	Homo sapiens	5α-dihydrotestosterone-17β-sulfate	0.017	0.0042	4		PMID 19218247	Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), 5α-dihydrotestosterone-17β-sulfate
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)	Homo sapiens	tibolone-17β-sulfate	0.202	0.0012	170		PMID 19218247	Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), tibolone-17β-sulfate
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)	Macaca fuscata (Japanese monkey)	camphorquinone	—	0.1	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase), camphorquinone
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)	Macaca fuscata (Japanese monkey)	D-xylose25 mM Tris-HCl	—	4.4	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase), D-xylose
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)	Macaca fuscata (Japanese monkey)	D-xylose0.1 M phosphate buffer; pH 7.5	—	6.3	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase), D-xylose
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)	Macaca fuscata (Japanese monkey)	NADP+25 mM Tris-HCl	—	5.5 × 10⁻⁴	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase), NADP+
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)	Macaca fuscata (Japanese monkey)	NADP+0.1 M phosphate buffer; pH 7.5	—	0.0021	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase), NADP+
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)	Macaca fuscata (Japanese monkey)	NADPH	—	5.6 × 10⁻⁴	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase), NADPH
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)variant H79Q	Macaca fuscata (Japanese monkey)	camphorquinone	—	0.51	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase) variant H79Q, camphorquinone
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)variant H79Q	Macaca fuscata (Japanese monkey)	D-xylose25 mM Tris-HCl; D-xylose varied with 0.25 mM NADP+	—	67	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase) variant H79Q, D-xylose
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)variant H79Q	Macaca fuscata (Japanese monkey)	D-xylose0.1 M phosphate buffer; pH 7.5; cosubstrate NADP+ (2.0 mM)	—	213	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase) variant H79Q, D-xylose
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)variant H79Q	Macaca fuscata (Japanese monkey)	NADP+25 mM Tris-HCl; cosubstrate D-xylose (0.4 M)	—	0.014	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase) variant H79Q, NADP+
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)variant H79Q	Macaca fuscata (Japanese monkey)	NADP+0.1 M phosphate buffer; pH 7.5; cosubstrate D-xylose (1.0 M)	—	0.402	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase) variant H79Q, NADP+
D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase)variant H79Q	Macaca fuscata (Japanese monkey)	NADPH	—	0.028	—	pH 7.5, 25 °C	PMID 11097839	Open record: D-xylose/dihydrodiol dehydrogenase (dimeric dihydrodiol dehydrogenase) variant H79Q, NADPH
dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	1-acenaphthenol	—	0.23	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme), 1-acenaphthenol
dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	17beta-hydroxyandrost-4-en-3-one	—	0.012	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme), 17beta-hydroxyandrost-4-en-3-one
dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5alpha-androstan-17beta-ol-3-one	—	0.01	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme), 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5beta-androstan-17beta-ol-3-one	—	0.007	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme), 5beta-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	trans-1,2-dihydrobenzene-1,2-diol	—	0.2	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D1 (testosterone 17beta-dehydrogenase isozyme), trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	1-acenaphthenol	—	0.2	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme), 1-acenaphthenol
dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	17beta-hydroxyandrost-4-en-3-one	—	0.008	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme), 17beta-hydroxyandrost-4-en-3-one
dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5alpha-androstan-17beta-ol-3-one	—	0.009	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme), 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5beta-androstan-17beta-ol-3-one	—	0.01	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme), 5beta-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	trans-1,2-dihydrobenzene-1,2-diol	—	0.19	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D2 (testosterone 17beta-dehydrogenase isozyme), trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	1-acenaphthenol	—	0.28	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme), 1-acenaphthenol
dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	17beta-hydroxyandrost-4-en-3-one	—	0.009	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme), 17beta-hydroxyandrost-4-en-3-one
dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5alpha-androstan-17beta-ol-3-one	—	0.008	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme), 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5beta-androstan-17beta-ol-3-one	—	0.006	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme), 5beta-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	trans-1,2-dihydrobenzene-1,2-diol	—	0.26	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D3 (testosterone 17beta-dehydrogenase isozyme), trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	1-acenaphthenol	—	0.24	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme), 1-acenaphthenol
dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	17beta-hydroxyandrost-4-en-3-one	—	0.01	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme), 17beta-hydroxyandrost-4-en-3-one
dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5alpha-androstan-17beta-ol-3-one	—	0.007	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme), 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5beta-androstan-17beta-ol-3-one	—	0.006	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme), 5beta-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	trans-1,2-dihydrobenzene-1,2-diol	—	0.29	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D4 (testosterone 17beta-dehydrogenase isozyme), trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase D5 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	17beta-hydroxyandrost-4-en-3-one	—	0.009	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D5 (testosterone 17beta-dehydrogenase isozyme), 17beta-hydroxyandrost-4-en-3-one
dihydrodiol dehydrogenase D5 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5beta-androstan-17beta-ol-3-one	—	0.005	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D5 (testosterone 17beta-dehydrogenase isozyme), 5beta-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D5 (testosterone 17beta-dehydrogenase isozyme)	guinea pig	trans-1,2-dihydrobenzene-1,2-diol	—	0.21	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D5 (testosterone 17beta-dehydrogenase isozyme), trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme)	guinea pig	1-acenaphthenol	—	0.12	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme), 1-acenaphthenol
dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme)	guinea pig	17beta-hydroxyandrost-4-en-3-one	—	0.048	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme), 17beta-hydroxyandrost-4-en-3-one
dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5alpha-androstan-17beta-ol-3-one	—	0.044	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme), 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5beta-androstan-17beta-ol-3-one	—	0.035	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme), 5beta-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme)	guinea pig	trans-1,2-dihydrobenzene-1,2-diol	—	7.2	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6a (testosterone 17beta-dehydrogenase isozyme), trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme)	guinea pig	1-acenaphthenol	—	0.22	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme), 1-acenaphthenol
dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme)	guinea pig	17beta-hydroxyandrost-4-en-3-one	—	0.123	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme), 17beta-hydroxyandrost-4-en-3-one
dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5alpha-androstan-17beta-ol-3-one	—	0.155	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme), 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme)	guinea pig	5beta-androstan-17beta-ol-3-one	—	0.014	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme), 5beta-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme)	guinea pig	trans-1,2-dihydrobenzene-1,2-diol	—	5.2	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D6b (testosterone 17beta-dehydrogenase isozyme), trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase D7 (aldehyde reductase)	guinea pig	trans-1,2-dihydrobenzene-1,2-diol	—	5	—	25 °C	PMID 3535806	Open record: dihydrodiol dehydrogenase D7 (aldehyde reductase), trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase DD1	Homo sapiens	(+/-)-trans-1,2-dihydroxy-3,5-cyclohexadiene	0.048	0.15	0.32	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD1, (+/-)-trans-1,2-dihydroxy-3,5-cyclohexadiene
dihydrodiol dehydrogenase DD1	Homo sapiens	1-acenaphthenol	0.49	0.022	22	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD1, 1-acenaphthenol
dihydrodiol dehydrogenase DD1	Homo sapiens	1-indanol	0.208	0.048	4.3	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD1, 1-indanol
dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase)	Bos taurus	chenodeoxycholic acid	0.0115	0.0045	2.7	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase), chenodeoxycholic acid
dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase)	Bos taurus	cholic acid	0.045	0.16	0.3	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase), cholic acid
dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase)	Bos taurus	deoxycholic acid	0.133	0.0042	32	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase), deoxycholic acid
dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase)	Bos taurus	lithocholic acid	0.0065	0.0016	4.2	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase), lithocholic acid
dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase)	Bos taurus	taurochenodeoxycholic acid	0.37	0.018	20	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase), taurochenodeoxycholic acid
dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase)	Bos taurus	taurocholic acid	0.07	0.21	0.35	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase), taurocholic acid
dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase)	Bos taurus	taurolithocholic acid	0.082	0.0038	22	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD1 (3alpha-hydroxysteroid dehydrogenase), taurolithocholic acid
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	(R)-1,2,3,4-tetrahydronaphthalen-1-ol	0.023	0.056	0.33	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), (R)-1,2,3,4-tetrahydronaphthalen-1-ol
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	4-Chromanol	0.8	0.073	10.8	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 4-Chromanol
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	4-Chromanone	0.112	0.0031	37	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 4-Chromanone
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	4-Pregnen-20α-ol-3-one	0.072	0.012	5.8	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 4-Pregnen-20α-ol-3-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Androstan-17β-ol-3-one	0.018	0.011	1.7	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Androstan-17β-ol-3-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-androstan-17β-ol-3-one	8.3 × 10⁻⁴	—	—	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-androstan-17β-ol-3-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Androstan-3α-ol-17-one	0.0065	0.01	0.67	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Androstan-3α-ol-17-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Androstane-3,17-dione	0.023	0.0022	10.7	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Androstane-3,17-dione
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Androstane-3α,17β-diol	0.0083	0.013	0.67	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Androstane-3α,17β-diol
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Pregnan-20α-ol-3-one	0.143	0.0021	68	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Pregnan-20α-ol-3-one	0.015	9 × 10⁻⁴	18	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Pregnan-3α-ol-20-one	0.0037	0.0037	1	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Pregnan-3α-ol-20-one	0.083	0.0023	37	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Pregnane-21-ol-3,20-dione	0.0153	0.0019	8	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Pregnane-21-ol-3,20-dione
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Pregnane-3,20-dione	0.047	5 × 10⁻⁴	93	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Pregnane-3,20-dione
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5α-Pregnane-3α,21-diol-20-one	0.0032	0.0028	1.2	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5α-Pregnane-3α,21-diol-20-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5β-Pregnan-20α-ol-3-one	0.105	0.0015	70	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5β-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5β-Pregnan-20α-ol-3-one	0.053	0.0017	32	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5β-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5β-Pregnan-3α-ol-20-one	0.0067	0.0028	2.3	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5β-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	5β-Pregnan-3α-ol-20-one	0.163	0.0038	43	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), 5β-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	Befunolol	0.093	0.027	3.5	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), Befunolol
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	Progesterone	0.022	7 × 10⁻⁴	30	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), Progesterone
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	Prostaglandin D2	0.018	0.011	1.7	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), Prostaglandin D2
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	S-(+)-1,2,3,4-tetrahydronaphth-1-ol	0.53	0.029	18	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), S-(+)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	S-Indan-1-ol	0.57	0.076	7.5	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), S-Indan-1-ol
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	trans-Benzene dihydrodiol	0.068	0.72	0.1	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), trans-Benzene dihydrodiol
dihydrodiol dehydrogenase DD1 (cyDD1)	Macaca fascicularis	α-Tetralone	0.057	0.001	57	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD1 (cyDD1), α-Tetralone
dihydrodiol dehydrogenase DD1 (human liver)	Homo sapiens	(S)-1,2,3,4-tetrahydronaphth-1-ol	0.23	0.005	47 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (human liver), (S)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase DD1 (human liver)	Homo sapiens	(S)-Indan-1-ol	0.17	0.038	4.4 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (human liver), (S)-Indan-1-ol
dihydrodiol dehydrogenase DD1 (human liver)	Homo sapiens	4-Pregnen-20α-ol-3-one	0.087	0.012	7.2 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (human liver), 4-Pregnen-20α-ol-3-one
dihydrodiol dehydrogenase DD1 (human liver)	Homo sapiens	5β-Androstane-3,17-dione	0.018	0.001	18 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (human liver), 5β-Androstane-3,17-dione
dihydrodiol dehydrogenase DD1 (human liver)	Homo sapiens	5β-Pregnan-20α-ol-3-one	0.048	0.003	16 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (human liver), 5β-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD1 (human liver)	Homo sapiens	5β-Pregnan-3α-ol-20-one	0.027	0.002	13 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (human liver), 5β-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD1 (human liver)	Homo sapiens	5β-Pregnane-3α,20α-diol	0.075	0.003	25 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (human liver), 5β-Pregnane-3α,20α-diol
dihydrodiol dehydrogenase DD1 (human liver)	Homo sapiens	Benzene dihydrodiol	0.053	0.58	0.092 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (human liver), Benzene dihydrodiol
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	(S)-1,2,3,4-tetrahydronaphth-1-ol	0.43	0.007	62 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), (S)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	(S)-Indan-1-ol	0.42	0.05	8.3 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), (S)-Indan-1-ol
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	4-Pregnen-20α-ol-3-one	0.25	0.013	19 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), 4-Pregnen-20α-ol-3-one
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	5β-Androstane-3,17-dione	0.043	0.002	22 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), 5β-Androstane-3,17-dione
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	5β-Pregnan-20α-ol-3-one	0.08	0.002	40 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), 5β-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	5β-Pregnan-3α-ol-20-one	0.032	0.001	32 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), 5β-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	5β-Pregnane-3α,20α-diol	0.132	0.003	44 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), 5β-Pregnane-3α,20α-diol
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	9α,11β-prostaglandin F2	0.118	0.138	0.860 calc.	pH 10, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), 9α,11β-prostaglandin F2
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	Benzene dihydrodiol	0.145	0.87	0.17 calc.	pH 7.4, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), Benzene dihydrodiol
dihydrodiol dehydrogenase DD1 (recombinant, rDD1)	Homo sapiens	prostaglandin D2	0.08	0.02	4.0 calc.	pH 6, 25 °C	PMID 8573067	Open record: dihydrodiol dehydrogenase DD1 (recombinant, rDD1), prostaglandin D2
dihydrodiol dehydrogenase DD2	Homo sapiens	(+/-)-trans-1,2-dihydroxy-3,5-cyclohexadiene	0.018	1.8	0.01	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD2, (+/-)-trans-1,2-dihydroxy-3,5-cyclohexadiene
dihydrodiol dehydrogenase DD2	Homo sapiens	1-acenaphthenol	0.585	0.022	27	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD2, 1-acenaphthenol
dihydrodiol dehydrogenase DD2	Homo sapiens	1-indanol	0.163	0.94	0.18	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD2, 1-indanol
dihydrodiol dehydrogenase DD2	Homo sapiens	5alpha-androstan-3alpha-ol-17-one	0.0067	0.0035	1.8	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD2, 5alpha-androstan-3alpha-ol-17-one
dihydrodiol dehydrogenase DD2 (AKR1C2)	Homo sapiens	(1S)-1,2,3,4-tetrahydronaphthalen-1-ol	0.2	0.14	1.4 calc.	pH 7.4, 25 °C	PMID 9716498	Open record: dihydrodiol dehydrogenase DD2 (AKR1C2), (1S)-1,2,3,4-tetrahydronaphthalen-1-ol
dihydrodiol dehydrogenase DD2 (AKR1C2)	Homo sapiens	(1S)-2,3-dihydro-1H-inden-1-ol	0.18	0.49	0.37 calc.	pH 7.4, 25 °C	PMID 9716498	Open record: dihydrodiol dehydrogenase DD2 (AKR1C2), (1S)-2,3-dihydro-1H-inden-1-ol
dihydrodiol dehydrogenase DD2 (AKR1C2)	Homo sapiens	11β-prostaglandin F2α (9α,11β-PGF2)	0.083	0.22	0.38 calc.	pH 10, 25 °C	PMID 9716498	Open record: dihydrodiol dehydrogenase DD2 (AKR1C2), 11β-prostaglandin F2α (9α,11β-PGF2)
dihydrodiol dehydrogenase DD2 (AKR1C2)	Homo sapiens	5β-pregnane-3α,20α-diol	0.0017	0.001	1.7 calc.	pH 7.4, 25 °C	PMID 9716498	Open record: dihydrodiol dehydrogenase DD2 (AKR1C2), 5β-pregnane-3α,20α-diol
dihydrodiol dehydrogenase DD2 (AKR1C2)	Homo sapiens	androsterone (3α-hydroxy-5α-androstan-17-one)recombinant	0.0067	0.0022	3.0 calc.	pH 7.4, 25 °C	PMID 9716498	Open record: dihydrodiol dehydrogenase DD2 (AKR1C2), androsterone (3α-hydroxy-5α-androstan-17-one)
dihydrodiol dehydrogenase DD2 (AKR1C2)	Homo sapiens	androsterone (3α-hydroxy-5α-androstan-17-one)native enzyme purified from human liver (hepatic DD2)	0.0067	0.002	3.3 calc.	pH 7.4, 25 °C	PMID 9716498	Open record: dihydrodiol dehydrogenase DD2 (AKR1C2), androsterone (3α-hydroxy-5α-androstan-17-one)
dihydrodiol dehydrogenase DD3	Bos taurus	(S)-(+)-1-indanol	0.42	0.33	1.27	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD3, (S)-(+)-1-indanol
dihydrodiol dehydrogenase DD3	Bos taurus	1-acenaphthenol	2	0.54	3.83	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD3, 1-acenaphthenol
dihydrodiol dehydrogenase DD3	Bos taurus	lithocholic acid	0.087	0.017	5	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD3, lithocholic acid
dihydrodiol dehydrogenase DD3	Bos taurus	NADP+	—	0.0027	—	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD3, NADP+
dihydrodiol dehydrogenase DD3	Bos taurus	taurochenodeoxycholic acid	0.78	0.89	0.88	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD3, taurochenodeoxycholic acid
dihydrodiol dehydrogenase DD3	Bos taurus	taurolithocholic acid	0.22	0.033	6.7	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD3, taurolithocholic acid
dihydrodiol dehydrogenase DD3	Bos taurus	trans-1,2-dihydrobenzene-1,2-diol	0.58	0.28	2	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD3, trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase DD3	Bos taurus	trans-1,2-dihydronaphthalene-1,2-diol	0.65	1.5	0.45	pH 9.5, 25 °C	PMID 7766669	Open record: dihydrodiol dehydrogenase DD3, trans-1,2-dihydronaphthalene-1,2-diol
dihydrodiol dehydrogenase DD3	Mus musculus	trans-1,2-dihydroxy-3,5-cyclohexadiene	—	5.1	—	pH 10, 25 °C	PMID 3276326	Open record: dihydrodiol dehydrogenase DD3, trans-1,2-dihydroxy-3,5-cyclohexadiene
dihydrodiol dehydrogenase DD4	Homo sapiens	(+/-)-trans-1,2-dihydroxy-3,5-cyclohexadiene	0.033	0.017	2	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD4, (+/-)-trans-1,2-dihydroxy-3,5-cyclohexadiene
dihydrodiol dehydrogenase DD4	Homo sapiens	1-acenaphthenol	0.125	0.14	0.25	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD4, 1-acenaphthenol
dihydrodiol dehydrogenase DD4	Homo sapiens	1-indanol	0.158	0.17	0.93	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD4, 1-indanol
dihydrodiol dehydrogenase DD4	Homo sapiens	5alpha-androstan-3alpha-ol-17-one	0.018	0.0035	5.2	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DD4, 5alpha-androstan-3alpha-ol-17-one
dihydrodiol dehydrogenase DD4	Mus musculus	trans-1,2-dihydroxy-3,5-cyclohexadiene	—	5.3	—	pH 10, 25 °C	PMID 3276326	Open record: dihydrodiol dehydrogenase DD4, trans-1,2-dihydroxy-3,5-cyclohexadiene
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	(R)-1,2,3,4-tetrahydronaphthalen-1-ol	0.7	0.382	1.3	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), (R)-1,2,3,4-tetrahydronaphthalen-1-ol
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	4-Chromanol	0.042	0.34	0.12	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 4-Chromanol
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	4-Pregnen-20α-ol-3-one	0.0127	3 × 10⁻⁴	42	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 4-Pregnen-20α-ol-3-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Androstan-17β-ol-3-one	0.04	8 × 10⁻⁴	50	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Androstan-17β-ol-3-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Androstan-3α-ol-17-one	0.2	7 × 10⁻⁴	280	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Androstan-3α-ol-17-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Androstane-3,17-dione	0.045	0.0013	35	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Androstane-3,17-dione
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Androstane-3α,17β-diol	0.22	6 × 10⁻⁴	350	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Androstane-3α,17β-diol
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Pregnan-20α-ol-3-one	0.025	2 × 10⁻⁴	125	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Pregnan-20α-ol-3-one	0.048	8 × 10⁻⁴	60	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Pregnan-3α-ol-20-one	0.153	3 × 10⁻⁴	520	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Pregnan-3α-ol-20-one	0.0072	4 × 10⁻⁴	18	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Pregnane-21-ol-3,20-dione	0.07	8 × 10⁻⁴	88	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Pregnane-21-ol-3,20-dione
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Pregnane-3,20-dione	0.08	9 × 10⁻⁴	88	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Pregnane-3,20-dione
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5α-Pregnane-3α,21-diol-20-one	0.38	6 × 10⁻⁴	630	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5α-Pregnane-3α,21-diol-20-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5β-Pregnan-20α-ol-3-one	0.0078	2 × 10⁻⁴	40	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5β-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5β-Pregnan-20α-ol-3-one	0.053	7 × 10⁻⁴	77	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5β-Pregnan-20α-ol-3-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5β-Pregnan-3α-ol-20-one	0.082	3 × 10⁻⁴	270	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5β-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	5β-Pregnan-3α-ol-20-one	0.013	4 × 10⁻⁴	30	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), 5β-Pregnan-3α-ol-20-one
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	S-(+)-1,2,3,4-tetrahydronaphth-1-ol	0.6	0.307	2	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), S-(+)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	S-Indan-1-ol	0.33	0.42	0.83	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), S-Indan-1-ol
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	trans-Benzene dihydrodiol	0.025	0.025	1	pH 7.4, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), trans-Benzene dihydrodiol
dihydrodiol dehydrogenase DD4 (jpDD4)	Macaca fuscata	α-Tetralone	0.025	0.038	0.67	pH 7, 25 °C	PMID 15618685	Open record: dihydrodiol dehydrogenase DD4 (jpDD4), α-Tetralone
dihydrodiol dehydrogenase DDX	Homo sapiens	(+/-)-trans-1,2-dihydroxy-3,5-cyclohexadiene	0.015	0.32	0.047	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DDX, (+/-)-trans-1,2-dihydroxy-3,5-cyclohexadiene
dihydrodiol dehydrogenase DDX	Homo sapiens	1-acenaphthenol	0.42	0.07	6	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DDX, 1-acenaphthenol
dihydrodiol dehydrogenase DDX	Homo sapiens	1-indanol	0.087	1.4	0.062	pH 7.4, 25 °C	PMID 9578563	Open record: dihydrodiol dehydrogenase DDX, 1-indanol
dihydrodiol dehydrogenase isoenzyme CF-1	Oryctolagus cuniculus	5alpha-androstan-17beta-ol-3-one	—	1.1	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-1, 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase isoenzyme CF-1	Oryctolagus cuniculus	5alpha-androstan-3alpha-ol-17-one	—	0.03	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-1, 5alpha-androstan-3alpha-ol-17-one
dihydrodiol dehydrogenase isoenzyme CF-1	Oryctolagus cuniculus	trans-1,2-dihydrobenzene-1,2-diol	—	0.23	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-1, trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase isoenzyme CF-2	Oryctolagus cuniculus	5alpha-androstan-17beta-ol-3-one	—	0.01	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-2, 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase isoenzyme CF-2	Oryctolagus cuniculus	5alpha-androstan-3alpha-ol-17-one	—	0.37	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-2, 5alpha-androstan-3alpha-ol-17-one
dihydrodiol dehydrogenase isoenzyme CF-2	Oryctolagus cuniculus	phenanthrene-9,10-quinone	—	0.03	—	pH 7.4, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-2, phenanthrene-9,10-quinone
dihydrodiol dehydrogenase isoenzyme CF-2	Oryctolagus cuniculus	trans-1,2-dihydrobenzene-1,2-diol	—	0.47	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-2, trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase isoenzyme CF-3	Oryctolagus cuniculus	5alpha-androstan-3alpha-ol-17-one	—	0.09	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-3, 5alpha-androstan-3alpha-ol-17-one
dihydrodiol dehydrogenase isoenzyme CF-3	Oryctolagus cuniculus	phenanthrene-9,10-quinone	—	0.05	—	pH 7.4, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-3, phenanthrene-9,10-quinone
dihydrodiol dehydrogenase isoenzyme CF-3	Oryctolagus cuniculus	trans-1,2-dihydrobenzene-1,2-diol	—	0.2	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-3, trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase isoenzyme CF-4	Oryctolagus cuniculus	trans-1,2-dihydrobenzene-1,2-diol	—	0.54	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-4, trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase isoenzyme CF-5	Oryctolagus cuniculus	5alpha-androstan-17beta-ol-3-one	—	0.01	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-5, 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase isoenzyme CF-5	Oryctolagus cuniculus	5alpha-androstan-3alpha-ol-17-one	—	0.01	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-5, 5alpha-androstan-3alpha-ol-17-one
dihydrodiol dehydrogenase isoenzyme CF-5	Oryctolagus cuniculus	phenanthrene-9,10-quinone	—	1.43	—	pH 7.4, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-5, phenanthrene-9,10-quinone
dihydrodiol dehydrogenase isoenzyme CF-5	Oryctolagus cuniculus	trans-1,2-dihydrobenzene-1,2-diol	—	6.33	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-5, trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase isoenzyme CF-6	Oryctolagus cuniculus	5alpha-androstan-17beta-ol-3-one	—	0.63	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-6, 5alpha-androstan-17beta-ol-3-one
dihydrodiol dehydrogenase isoenzyme CF-6	Oryctolagus cuniculus	5alpha-androstan-3alpha-ol-17-one	—	0.04	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-6, 5alpha-androstan-3alpha-ol-17-one
dihydrodiol dehydrogenase isoenzyme CF-6	Oryctolagus cuniculus	trans-1,2-dihydrobenzene-1,2-diol	—	5.75	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CF-6, trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase isoenzyme CM-1	Oryctolagus cuniculus	trans-1,2-dihydrobenzene-1,2-diol	—	7.47	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CM-1, trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase isoenzyme CM-2	Oryctolagus cuniculus	phenanthrene-9,10-quinone	—	0.06	—	pH 7.4, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CM-2, phenanthrene-9,10-quinone
dihydrodiol dehydrogenase isoenzyme CM-2	Oryctolagus cuniculus	trans-1,2-dihydrobenzene-1,2-diol	—	11.05	—	pH 9, 37 °C	PMID 1576998	Open record: dihydrodiol dehydrogenase isoenzyme CM-2, trans-1,2-dihydrobenzene-1,2-diol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	(R)-1,2,3,4-tetrahydronaphth-1-ol	0.18	0.16	1.1 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), (R)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	(S)-1,2,3,4-tetrahydronaphth-1-ol	0.2	0.11	1.8 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), (S)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	(S)-Indan-1-ol	0.102	0.146	0.700 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), (S)-Indan-1-ol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	5α-Androstane-3α,17β-diol	0.087	8 × 10⁻⁴	110 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), 5α-Androstane-3α,17β-diol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	5β-Androstan-3α-ol-17-one	0.048	9 × 10⁻⁴	54 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), 5β-Androstan-3α-ol-17-one
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	5β-androstane-3α,17β-diol	0.047	0.0012	39 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), 5β-androstane-3α,17β-diol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	Androsterone	0.043	5 × 10⁻⁴	87 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), Androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	androsteroneno activator (control row of the activator study)	0.043	5 × 10⁻⁴	87 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	androsteronewith 5 µM Sulphobromophthalein (non-essential activator)	0.45	0.0011	410 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	androsteronewith 50 µM (R)-Ibuprofen (non-essential activator)	0.17	7 × 10⁻⁴	240 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	androsteronewith 100 µM Clofibric acid (non-essential activator)	0.107	8 × 10⁻⁴	130 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	androsteronewith 1 µM L-Thyroxine (non-essential activator)	0.28	0.001	280 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	androsteronewith 1 µM D-Thyroxine (non-essential activator)	0.33	0.0012	280 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	Chenodeoxycholic acid	0.032	0.0011	29 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), Chenodeoxycholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	Cholic acid	0.2	0.059	3.4 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), Cholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	Deoxycholic acid	0.085	0.0097	8.8 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), Deoxycholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	Lithocholic acid	0.032	0.001	32 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), Lithocholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	NAD+	0.2	1.2	0.17	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), NAD+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	NADP+fluorimetric NAD(P)H production; Table 1	0.04	0.0017	23	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0016	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0019	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0017	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0018	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0019	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0017	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4), NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	(R)-1,2,3,4-tetrahydronaphth-1-ol	0.38	0.38	1.0 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, (R)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	(S)-1,2,3,4-tetrahydronaphth-1-ol	0.27	0.24	1.1 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, (S)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	(S)-Indan-1-ol	0.27	0.28	0.95 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, (S)-Indan-1-ol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	5α-Androstane-3α,17β-diol	0.3	0.0031	97 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, 5α-Androstane-3α,17β-diol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	5β-Androstan-3α-ol-17-one	0.135	0.0014	96 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, 5β-Androstan-3α-ol-17-one
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	5β-androstane-3α,17β-diol	0.165	0.0021	79 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, 5β-androstane-3α,17β-diol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	Androsterone	0.153	0.0022	70 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, Androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	androsteroneno activator (control row of the activator study)	0.153	0.0026	59 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	androsteronewith 5 µM Sulphobromophthalein (non-essential activator)	0.48	0.023	21 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	androsteronewith 50 µM (R)-Ibuprofen (non-essential activator)	0.22	0.0083	26 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	androsteronewith 100 µM Clofibric acid (non-essential activator)	0.25	0.01	25 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	androsteronewith 1 µM L-Thyroxine (non-essential activator)	0.32	0.014	23 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	androsteronewith 1 µM D-Thyroxine (non-essential activator)	0.32	0.013	24 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	Chenodeoxycholic acid	0.105	0.0023	46 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, Chenodeoxycholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	Cholic acid	0.03	0.032	0.94 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, Cholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	Deoxycholic acid	0.012	0.0014	8.3 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, Deoxycholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	Lithocholic acid	0.04	0.0018	22 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, Lithocholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	NAD+	0.33	1.2	0.28	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, NAD+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	NADP+fluorimetric NAD(P)H production; Table 1	0.16	6 × 10⁻⁴	270	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	5 × 10⁻⁴	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0014	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	6 × 10⁻⁴	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0011	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0013	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216F	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0015	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216F, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216W	Homo sapiens	androsterone	—	0.0072	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216W, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216W	Homo sapiens	NADP+	—	0.0067	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216W, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	(R)-1,2,3,4-tetrahydronaphth-1-ol	0.77	0.68	1.1 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, (R)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	(S)-1,2,3,4-tetrahydronaphth-1-ol	0.43	0.29	1.5 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, (S)-1,2,3,4-tetrahydronaphth-1-ol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	(S)-Indan-1-ol	0.4	0.42	0.95 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, (S)-Indan-1-ol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	5α-Androstane-3α,17β-diol	0.35	0.0026	130 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, 5α-Androstane-3α,17β-diol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	5β-Androstan-3α-ol-17-one	0.18	0.0018	100 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, 5β-Androstan-3α-ol-17-one
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	5β-androstane-3α,17β-diol	0.18	0.0022	83 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, 5β-androstane-3α,17β-diol
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	Androsterone	0.28	0.0027	100 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, Androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	androsteroneno activator (control row of the activator study)	0.3	0.0022	140 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	androsteronewith 5 µM Sulphobromophthalein (non-essential activator)	0.83	0.023	36 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	androsteronewith 50 µM (R)-Ibuprofen (non-essential activator)	0.38	0.005	77 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	androsteronewith 100 µM Clofibric acid (non-essential activator)	0.43	0.011	39 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	androsteronewith 1 µM L-Thyroxine (non-essential activator)	0.67	0.02	33 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	androsteronewith 1 µM D-Thyroxine (non-essential activator)	0.62	0.013	47 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, androsterone
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	Chenodeoxycholic acid	0.133	0.0029	46 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, Chenodeoxycholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	Cholic acid	0.05	0.041	1.2 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, Cholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	Deoxycholic acid	0.018	0.0013	14 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, Deoxycholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	Lithocholic acid	0.043	0.0019	23 calc.	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, Lithocholic acid
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	NAD+	0.58	1	0.58	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, NAD+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	NADP+fluorimetric NAD(P)H production; Table 1	0.25	5 × 10⁻⁴	500	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	5 × 10⁻⁴	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0025	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.001	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	9 × 10⁻⁴	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0018	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, NADP+
dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4)variant H216Y	Homo sapiens	NADP+androsterone dehydrogenase assay with NADP+; Table 4	—	0.0019	—	pH 7.4, 25 °C	PMID 11104674	Open record: dihydrodiol dehydrogenase/3alpha-hydroxysteroid dehydrogenase isoenzyme AKR1C4 (DD4) variant H216Y, NADP+
dimeric dihydrodiol dehydrogenase	Canis lupus familiaris	2-deoxy-D-glucose	—	97	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, 2-deoxy-D-glucose
dimeric dihydrodiol dehydrogenase	Canis lupus familiaris	D-galactose	—	95	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-galactose
dimeric dihydrodiol dehydrogenase	Canis lupus familiaris	D-glucose	—	49	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-glucose
dimeric dihydrodiol dehydrogenase	Canis lupus familiaris	D-ribose	—	7.3	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-ribose
dimeric dihydrodiol dehydrogenase	Canis lupus familiaris	D-xylose	—	1.6	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Canis lupus familiaris	L-xylose	—	27	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, L-xylose
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	2-deoxy-D-glucose	—	91	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, 2-deoxy-D-glucose
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	4-Nitrobenzaldehyde	11.3	3.3	3.4	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, 4-Nitrobenzaldehyde
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	Camphorquinone	62.5	0.17	368	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, Camphorquinone
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	D-galactose	—	137	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-galactose
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	D-glucose	—	29	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-glucose
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	D-Glyceraldehyde	31.4	45	0.7	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, D-Glyceraldehyde
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	D-ribose	—	26	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-ribose
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	D-xylose	—	6.4	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	Dihydroxyacetone	5.5	5.4	1	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, Dihydroxyacetone
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	Dihydroxyacetone phosphate	4.3	5	0.86	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, Dihydroxyacetone phosphate
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	DL-Glyceraldehyde-3-phosphate	8	50	0.16	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, DL-Glyceraldehyde-3-phosphate
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	L-Glyceraldehyde	9.1	121	0.08	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, L-Glyceraldehyde
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	L-xylose	—	42	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, L-xylose
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	NADPH	—	5 × 10⁻⁴	—	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, NADPH
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	trans-1,2-dihydro-1,2-dihydroxynaphthalene	34	2.7	12.6	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, trans-1,2-dihydro-1,2-dihydroxynaphthalene
dimeric dihydrodiol dehydrogenase	Macaca fuscata (Japanese monkey)	trans-1,2-dihydrobenzene-1,2-diol	14	2.6	5.4	pH 7.4, 25 °C	PMID 2697716	Open record: dimeric dihydrodiol dehydrogenase, trans-1,2-dihydrobenzene-1,2-diol
dimeric dihydrodiol dehydrogenase	Oryctolagus cuniculus	2-deoxy-D-glucose	—	25	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, 2-deoxy-D-glucose
dimeric dihydrodiol dehydrogenase	Oryctolagus cuniculus	D-galactose	—	170	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-galactose
dimeric dihydrodiol dehydrogenase	Oryctolagus cuniculus	D-glucose	—	58	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-glucose
dimeric dihydrodiol dehydrogenase	Oryctolagus cuniculus	D-ribose	—	10	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-ribose
dimeric dihydrodiol dehydrogenase	Oryctolagus cuniculus	D-xylose	—	4.4	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Oryctolagus cuniculus	L-xylose	—	83	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, L-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	2-deoxy-D-glucose	—	8.7	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, 2-deoxy-D-glucose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-galactose	—	35	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-galactose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-glucose	—	19	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-glucose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-ribose	—	3.3	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-ribose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose0.1 M potassium phosphate buffer; liver	—	0.8	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose	—	2.1	—	pH 7.5, 30 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose0.1 M potassium phosphate buffer	—	0.7	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose25 mM Tris-HCl buffer (TB)	—	0.46	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose25 mM Tris-HCl buffer (TB); + 20 mM MgCl2	—	1.3	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose25 mM Tris-HCl buffer (TB); + 0.1 M KCl	—	1.2	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose100 mM Tris-HCl buffer (TB)	—	0.9	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose25 mM potassium phosphate buffer (PB)	—	0.28	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose25 mM potassium phosphate buffer (PB); + 20 mM MgCl2	—	2.3	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose25 mM potassium phosphate buffer (PB); + 0.1 M KCl	—	1.9	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	D-xylose100 mM potassium phosphate buffer (PB)	—	0.68	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, D-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	L-xylose	—	24	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, L-xylose
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+	—	0.0035	—	pH 7.5, 30 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+0.1 M potassium phosphate buffer	—	0.013	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+25 mM Tris-HCl buffer (TB)	—	3.9 × 10⁻⁴	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+25 mM Tris-HCl buffer (TB); + 20 mM MgCl2	—	0.0011	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+25 mM Tris-HCl buffer (TB); + 0.1 M KCl	—	9.5 × 10⁻⁴	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+100 mM Tris-HCl buffer (TB)	—	8.2 × 10⁻⁴	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+25 mM potassium phosphate buffer (PB)	—	5.9 × 10⁻⁴	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+25 mM potassium phosphate buffer (PB); + 20 mM MgCl2	—	0.0011	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+25 mM potassium phosphate buffer (PB); + 0.1 M KCl	—	0.0012	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase	Sus scrofa	NADP+100 mM potassium phosphate buffer (PB)	—	0.0019	—	pH 7.5, 25 °C	PMID 11306093	Open record: dimeric dihydrodiol dehydrogenase, NADP+
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	(1R,2R)-cyclohexane-1,2-diolNADP+-linked dehydrogenase activity	—	0.81	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), (1R,2R)-cyclohexane-1,2-diol
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	(1R,2R)-cyclohexane-1,2-diolconstants from secondary replots	—	0.87	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), (1R,2R)-cyclohexane-1,2-diol
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	(1R,2R)-trans-1,2-dihydroxycyclohexa-3,5-diene	—	0.05	—		PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), (1R,2R)-trans-1,2-dihydroxycyclohexa-3,5-diene
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	2,3-Heptanedione	—	0.83	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), 2,3-Heptanedione
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	2,3-Hexanedione	—	1.1	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), 2,3-Hexanedione
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	2,3-Pentanedione	—	0.13	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), 2,3-Pentanedione
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	3-Deoxyglucosone	—	0.68	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), 3-Deoxyglucosone
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	3-Nitrobenzaldehyde	—	1.4	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), 3-Nitrobenzaldehyde
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	4-Nitrobenzaldehyde	—	5.9	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), 4-Nitrobenzaldehyde
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Acetoin	—	0.67	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Acetoin
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Camphorquinone	—	0.07	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Camphorquinone
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	D-Glyceraldehyde	—	2.1	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), D-Glyceraldehyde
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	D-Lactaldehyde	—	1.1	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), D-Lactaldehyde
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Diacetyl	—	0.02	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Diacetyl
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Dihydroxyacetone	—	3.4	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Dihydroxyacetone
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Ethyl pyruvate	—	0.73	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Ethyl pyruvate
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	L-Glyceraldehyde	—	0.96	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), L-Glyceraldehyde
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	L-Lactaldehyde	—	0.67	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), L-Lactaldehyde
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Methyl pyruvate	—	0.59	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Methyl pyruvate
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Methylglyoxal	—	0.21	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Methylglyoxal
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	NADP+fixed 5 mM [1R,2R]-trans-cyclohexanediol	—	0.002	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), NADP+
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	NADP+constants from secondary replots	—	0.0017	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), NADP+
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	NADPH	—	0.004	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), NADPH
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Phenyl-1,2-propanedione	—	0.12	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Phenyl-1,2-propanedione
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Phenylglyoxal	—	0.81	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Phenylglyoxal
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	Pyridine-3-aldehyde	—	2	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), Pyridine-3-aldehyde
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	trans-1,2-dihydroxy-1,2-dihydronaphthalene	—	1.6	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), trans-1,2-dihydroxy-1,2-dihydronaphthalene
dimeric dihydrodiol dehydrogenase (DD)	Canis lupus familiaris	trans-1,2-dihydroxycyclohexa-3,5-diene	—	0.27	—	pH 7.5, 25 °C	PMID 7852295	Open record: dimeric dihydrodiol dehydrogenase (DD), trans-1,2-dihydroxycyclohexa-3,5-diene
human type 3 3α-hydroxysteroid dehydrogenase (h3α-HSD3)variant Y24A	Homo sapiens	androst-4-ene-3,17-dione17α-HSD activity (17α-reduction of Δ4)	3.3 × 10⁻⁴	0.02094	0.017	pH 7.3, 37 °C	PMID 17442338	Open record: human type 3 3α-hydroxysteroid dehydrogenase (h3α-HSD3) variant Y24A, androst-4-ene-3,17-dione
human type 3 3α-hydroxysteroid dehydrogenase (h3α-HSD3)variant Y24A	Homo sapiens	androst-4-ene-3,17-dione17β-HSD activity (17β-reduction of Δ4 to testosterone)	0.0215	0.02957	0.73	pH 7.3, 37 °C	PMID 17442338	Open record: human type 3 3α-hydroxysteroid dehydrogenase (h3α-HSD3) variant Y24A, androst-4-ene-3,17-dione