CatLogenzyme kinetics catalog

Values CatLog read from this paper

Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone…

PMID 14672942doi:10.1074/jbc.m313308200Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 7 records (9 values) from this paper: AKR1C2, AKR1C1, AKR1C3 and 1 more from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.51, EC 1.1.1.53, EC 1.1.1.62, EC 1.1.1.64, EC 1.1.1.112, EC 1.1.1.149, EC 1.1.1.188, EC 1.1.1.209, EC 1.1.1.210, EC 1.1.1.225, EC 1.1.1.239, EC 1.1.1.270, EC 1.1.1.357, EC 1.3.1.20

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
AKR1C1Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)0.0125——pH 7, 37 °COpen
AKR1C2Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)radiometric time courses; apparent kcat0.0492——pH 7, 37 °COpen
AKR1C2Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)radiometric assay; [4-14C]DHT; DHT 1.6-41.25 µM—0.0066—pH 7, 37 °COpen
AKR1C2Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)radiometric assay; [4-14C]DHT; DHT 1.6-41.25 µM—0.011—pH 7, 37 °COpen
AKR1C2Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)0.05170.004311.937 °COpen
AKR1C3Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)0.0038——pH 7, 37 °COpen
AKR1C4Homo sapiens17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone)0.0938——pH 7, 37 °COpen