Values CatLog read from this paper
Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity
PMID 24434280doi:10.1016/j.jsbmb.2014.01.003Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 4 records (12 values) from this paper: 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 1.1.1.51, EC 1.1.1.62, EC 1.1.1.112, EC 1.1.1.209, EC 1.1.1.357, EC 1.3.1.20
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2) | Homo sapiens | 5α-dihydrotestosterone | 0.0612 | 0.00218 | 28 | pH 7.4, 37 °C | Open record: 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2), 5α-dihydrotestosterone |
| 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2) | Homo sapiens | progesterone | 0.0035 | 8.4 × 10⁻⁴ | 4.2 | pH 7.4, 37 °C | Open record: 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2), progesterone |
| 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)variant V54L | Homo sapiens | 5α-dihydrotestosterone | 0.1153 | 0.07103 | 1.7 | pH 7.4, 37 °C | Open record: 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2) variant V54L, 5α-dihydrotestosterone |
| 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)variant V54L | Homo sapiens | progesterone | 0.0392 | 0.00213 | 18.3 | pH 7.4, 37 °C | Open record: 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2) variant V54L, progesterone |