Values CatLog read from this paper

Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism

PMID 19218247doi:10.1074/jbc.m809465200Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 12 records (30 values) from this paper: aldo-keto reductase AKR1C1 (human 20α-HSD), aldo-keto reductase AKR1C2 (human type 3 3α-HSD), aldo-keto reductase AKR1C4 (human type 1 3α-HSD) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.51, EC 1.1.1.53, EC 1.1.1.62, EC 1.1.1.112, EC 1.1.1.149, EC 1.1.1.209, EC 1.1.1.210, EC 1.1.1.225, EC 1.1.1.270, EC 1.1.1.357, EC 1.3.1.20

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
aldo-keto reductase AKR1C1 (human 20α-HSD)Homo sapiens5α-dihydrotestosterone0.01230.00423Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), 5α-dihydrotestosterone
aldo-keto reductase AKR1C1 (human 20α-HSD)Homo sapiens5α-dihydrotestosterone-17β-glucuronide0.00880.01610.55Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), 5α-dihydrotestosterone-17β-glucuronide
aldo-keto reductase AKR1C1 (human 20α-HSD)Homo sapiens5α-dihydrotestosterone-17β-sulfate0.01250.00522.3Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), 5α-dihydrotestosterone-17β-sulfate
aldo-keto reductase AKR1C1 (human 20α-HSD)Homo sapienstibolone-17β-sulfate0.0320.002512.7Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), tibolone-17β-sulfate
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)Homo sapiens5α-dihydrotestosterone0.0330.002911.3Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), 5α-dihydrotestosterone
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)Homo sapiens5α-dihydrotestosterone-17β-glucuronide0.0040.00410.98Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), 5α-dihydrotestosterone-17β-glucuronide
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)Homo sapiens5α-dihydrotestosterone-17β-sulfate0.0170.00424Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), 5α-dihydrotestosterone-17β-sulfate
aldo-keto reductase AKR1C2 (human type 3 3α-HSD)Homo sapienstibolone-17β-sulfate0.2020.0012170Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), tibolone-17β-sulfate
aldo-keto reductase AKR1C4 (human type 1 3α-HSD)Homo sapiens5α-dihydrotestosterone0.0513——Open record: aldo-keto reductase AKR1C4 (human type 1 3α-HSD), 5α-dihydrotestosterone
aldo-keto reductase AKR1C4 (human type 1 3α-HSD)Homo sapiens5α-dihydrotestosterone-17β-glucuronide0.0547——Open record: aldo-keto reductase AKR1C4 (human type 1 3α-HSD), 5α-dihydrotestosterone-17β-glucuronide
aldo-keto reductase AKR1C4 (human type 1 3α-HSD)Homo sapiens5α-dihydrotestosterone-17β-sulfate0.0512——Open record: aldo-keto reductase AKR1C4 (human type 1 3α-HSD), 5α-dihydrotestosterone-17β-sulfate
aldo-keto reductase AKR1C4 (human type 1 3α-HSD)Homo sapienstibolone-17β-sulfate0.025 × 10⁻⁴40Open record: aldo-keto reductase AKR1C4 (human type 1 3α-HSD), tibolone-17β-sulfate