Values CatLog read from this paper
Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism
PMID 19218247doi:10.1074/jbc.m809465200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (30 values) from this paper: aldo-keto reductase AKR1C1 (human 20α-HSD), aldo-keto reductase AKR1C2 (human type 3 3α-HSD), aldo-keto reductase AKR1C4 (human type 1 3α-HSD) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 1.1.1.51, EC 1.1.1.53, EC 1.1.1.62, EC 1.1.1.112, EC 1.1.1.149, EC 1.1.1.209, EC 1.1.1.210, EC 1.1.1.225, EC 1.1.1.270, EC 1.1.1.357, EC 1.3.1.20
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| aldo-keto reductase AKR1C1 (human 20α-HSD) | Homo sapiens | 5α-dihydrotestosterone | 0.0123 | 0.0042 | 3 | Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), 5α-dihydrotestosterone | |
| aldo-keto reductase AKR1C1 (human 20α-HSD) | Homo sapiens | 5α-dihydrotestosterone-17β-glucuronide | 0.0088 | 0.0161 | 0.55 | Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), 5α-dihydrotestosterone-17β-glucuronide | |
| aldo-keto reductase AKR1C1 (human 20α-HSD) | Homo sapiens | 5α-dihydrotestosterone-17β-sulfate | 0.0125 | 0.0052 | 2.3 | Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), 5α-dihydrotestosterone-17β-sulfate | |
| aldo-keto reductase AKR1C1 (human 20α-HSD) | Homo sapiens | tibolone-17β-sulfate | 0.032 | 0.0025 | 12.7 | Open record: aldo-keto reductase AKR1C1 (human 20α-HSD), tibolone-17β-sulfate | |
| aldo-keto reductase AKR1C2 (human type 3 3α-HSD) | Homo sapiens | 5α-dihydrotestosterone | 0.033 | 0.0029 | 11.3 | Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), 5α-dihydrotestosterone | |
| aldo-keto reductase AKR1C2 (human type 3 3α-HSD) | Homo sapiens | 5α-dihydrotestosterone-17β-glucuronide | 0.004 | 0.0041 | 0.98 | Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), 5α-dihydrotestosterone-17β-glucuronide | |
| aldo-keto reductase AKR1C2 (human type 3 3α-HSD) | Homo sapiens | 5α-dihydrotestosterone-17β-sulfate | 0.017 | 0.0042 | 4 | Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), 5α-dihydrotestosterone-17β-sulfate | |
| aldo-keto reductase AKR1C2 (human type 3 3α-HSD) | Homo sapiens | tibolone-17β-sulfate | 0.202 | 0.0012 | 170 | Open record: aldo-keto reductase AKR1C2 (human type 3 3α-HSD), tibolone-17β-sulfate | |
| aldo-keto reductase AKR1C4 (human type 1 3α-HSD) | Homo sapiens | 5α-dihydrotestosterone | 0.0513 | — | — | Open record: aldo-keto reductase AKR1C4 (human type 1 3α-HSD), 5α-dihydrotestosterone | |
| aldo-keto reductase AKR1C4 (human type 1 3α-HSD) | Homo sapiens | 5α-dihydrotestosterone-17β-glucuronide | 0.0547 | — | — | Open record: aldo-keto reductase AKR1C4 (human type 1 3α-HSD), 5α-dihydrotestosterone-17β-glucuronide | |
| aldo-keto reductase AKR1C4 (human type 1 3α-HSD) | Homo sapiens | 5α-dihydrotestosterone-17β-sulfate | 0.0512 | — | — | Open record: aldo-keto reductase AKR1C4 (human type 1 3α-HSD), 5α-dihydrotestosterone-17β-sulfate | |
| aldo-keto reductase AKR1C4 (human type 1 3α-HSD) | Homo sapiens | tibolone-17β-sulfate | 0.02 | 5 × 10⁻⁴ | 40 | Open record: aldo-keto reductase AKR1C4 (human type 1 3α-HSD), tibolone-17β-sulfate |