CatLogenzyme kinetics catalog

Values CatLog read from this paper

Characterization of structural and functional properties of human 17 beta-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesis

PMID 8994190doi:10.1210/mend.11.1.9872Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 18 records (18 values) from this paper: 17beta-hydroxysteroid dehydrogenase type 1 from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.62

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
17beta-hydroxysteroid dehydrogenase type 1Homo sapiens17beta-estradiolpurified (Reactive Red-agarose, Mono Q)—0.00211—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1Homo sapiens17beta-estradiol—0.00229—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1Homo sapiensestronepurified (Reactive Red-agarose, Mono Q)—9 × 10⁻⁴—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1Homo sapiensestrone—0.00138—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant E282AHomo sapiens17beta-estradiol—0.00163—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant E282AHomo sapiensestrone—0.00113—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant E282QHomo sapiens17beta-estradiol—0.0018—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant E282QHomo sapiensestrone—6.6 × 10⁻⁴—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant H221A/E282AHomo sapiens17beta-estradiol—0.00374—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant H221A/E282AHomo sapiensestrone—0.00511—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant H221A/E282QHomo sapiens17beta-estradiol—0.00428—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant H221A/E282QHomo sapiensestrone—0.00375—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant K159AHomo sapiens17beta-estradiol—0.00539—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant K159AHomo sapiensestrone—0.00114—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant S134AHomo sapiens17beta-estradiol—0.00253—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant S134AHomo sapiensestrone—7.8 × 10⁻⁴—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant S142AHomo sapiens17beta-estradiol—0.00526—pH 7.5, 37 °COpen
17beta-hydroxysteroid dehydrogenase type 1variant S142AHomo sapiensestrone—0.00166—pH 7.5, 37 °COpen