Values CatLog read from this paper
Catalytic activity of human indoleamine 2,3-dioxygenase (hIDO1) at low oxygen
PMID 25712221doi:10.1016/j.abb.2015.02.014Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 16 records (45 values) from this paper: indoleamine 2,3-dioxygenase 1 (hIDO1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 3 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | dioxygenfixed [L-Trp] = 8.33 µM; O2 varied 11.5-230 µM (Fig. 2B) | 3.7 | 0.0237 | 150 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | dioxygenfixed [L-Trp] = 10.0 µM; O2 varied 11.5-230 µM (Fig. 2B) | 4.2 | 0.024 | 170 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | dioxygenfixed [L-Trp] = 13.3 µM; O2 varied 11.5-230 µM (Fig. 2B) | 4.1 | 0.0142 | 280 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | dioxygenfixed [L-Trp] = 16.7 µM; O2 varied 11.5-230 µM (Fig. 2B) | 4.4 | 0.0115 | 380 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | dioxygenfixed [L-Trp] = 20.0 µM; O2 varied 11.5-230 µM (Fig. 2B) | 4.8 | 0.014 | 340 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | dioxygenfixed [L-Trp] = 50.0 µM; O2 varied 4.6-348 µM (Fig. 2B) | 5.8 | 0.0186 | 310 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5 | 8.2 | 0.019 | 430 calc. | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 20 mM ascorbate; 10 µM methylene blue | 8.7 | 0.028 | 310 calc. | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 20 mM ascorbate; 10 µM methylene blue | 8.9 | 0.029 | 310 calc. | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5 | 7.1 | 0.0211 | 330 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5 | 8.5 | 0.024 | 350 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5 | 8.5 | 0.0207 | 410 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5 | 8.9 | 0.0201 | 440 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5 | 9.7 | 0.0234 | 410 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5 | 10.3 | 0.0256 | 400 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 1 (hIDO1) | Homo sapiens | L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5 | 8.3 | 0.019 | 440 | pH 7, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan |