EC 1.13.11.52: indoleamine 2,3-dioxygenase

OxidoreductasesOpen in Browse

CatLog read 95 records for EC 1.13.11.52 from 13 papers, for 17 organisms. Names in these papers: indoleamine 2,3-dioxygenase 1 (hIDO1), indoleamine 2,3-dioxygenase 2 (IDO2), indoleamine 2,3-dioxygenase, indoleamine 2,3-dioxygenase (hIDO) and 17 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 72 records for EC 1.13.11.52 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.13.11.52 in Browse.

Papers

Papers with records for EC 1.13.11.52
Paper	Organisms	Records
Low efficiency IDO2 enzymes are conserved in lower vertebrates, whereas higher efficiency IDO1 enzymes are dispensable	Anolis carolinensis, Gallus gallus and 5 more	18
Catalytic activity of human indoleamine 2,3-dioxygenase (hIDO1) at low oxygen	Homo sapiens	16
Evolution of vertebrate indoleamine 2,3-dioxygenases	Danio rerio, Homo sapiens and 3 more	11
1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan	Danio rerio, Gallus gallus and 3 more	10
The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenase	Homo sapiens	9
Molecular evolution and characterization of fungal indoleamine 2,3-dioxygenases	Aspergillus oryzae, Saccharomyces cerevisiae	8
Inhibitory substrate binding site of human indoleamine 2,3-dioxygenase	Homo sapiens	6
A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase	Homo sapiens	5
Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1	Homo sapiens	4
Efficient tryptophan-catabolizing activity is consistently conserved through evolution of TDO enzymes, but not IDO enzymes	Branchiostoma floridae, Haliotis diversicolor and 2 more	4
Reassessment of the reaction mechanism in the heme dioxygenases	Homo sapiens	2
Monooxygenase Activity of Indoleamine 2,3-Dioxygenase	Homo sapiens	1
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1	Homo sapiens	1

Records

Records for EC 1.13.11.52 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
IDO paralogue (proto-IDO, IDO-2)	Mus musculus	L-tryptophan	1.545	38.85	0.0398	pH 6.5, 37 °C	PMID 18026683	Open record: IDO paralogue (proto-IDO, IDO-2), L-tryptophan
IDO paralogue (proto-IDO, IDO-2)	Mus musculus	L-tryptophan	—	45	—		PMID 18026683	Open record: IDO paralogue (proto-IDO, IDO-2), L-tryptophan
indoleamine 2,3-dioxygenase	Homo sapiens	L-tryptophan	1.4	0.005	280 calc.	pH 8, 20 °C	PMID 22299628	Open record: indoleamine 2,3-dioxygenase, L-tryptophan
indoleamine 2,3-dioxygenasevariant F163A	Homo sapiens	L-tryptophan	0.04	0.068	0.59 calc.	pH 8, 20 °C	PMID 22299628	Open record: indoleamine 2,3-dioxygenase variant F163A, L-tryptophan
indoleamine 2,3-dioxygenasevariant F164A	Homo sapiens	L-tryptophan	0.68	0.16	4.2 calc.	pH 8, 20 °C	PMID 22299628	Open record: indoleamine 2,3-dioxygenase variant F164A, L-tryptophan
indoleamine 2,3-dioxygenasevariant F226A	Homo sapiens	L-tryptophan	0.12	0.31	0.39 calc.	pH 8, 20 °C	PMID 22299628	Open record: indoleamine 2,3-dioxygenase variant F226A, L-tryptophan
indoleamine 2,3-dioxygenasevariant F226Y	Homo sapiens	L-tryptophan	6	0.16	38 calc.	pH 8, 20 °C	PMID 22299628	Open record: indoleamine 2,3-dioxygenase variant F226Y, L-tryptophan
indoleamine 2,3-dioxygenasevariant F227A	Homo sapiens	L-tryptophan	0.4	0.015	27 calc.	pH 8, 20 °C	PMID 22299628	Open record: indoleamine 2,3-dioxygenase variant F227A, L-tryptophan
indoleamine 2,3-dioxygenasevariant R231K	Homo sapiens	L-tryptophan	0.3	—	—	pH 8, 20 °C	PMID 22299628	Open record: indoleamine 2,3-dioxygenase variant R231K, L-tryptophan
indoleamine 2,3-dioxygenasevariant S167A	Homo sapiens	L-tryptophan	1.6	0.022	73 calc.	pH 8, 20 °C	PMID 22299628	Open record: indoleamine 2,3-dioxygenase variant S167A, L-tryptophan
indoleamine 2,3-dioxygenasevariant S167H	Homo sapiens	L-tryptophan	0.006	0.026	0.23 calc.	pH 8, 20 °C	PMID 22299628	Open record: indoleamine 2,3-dioxygenase variant S167H, L-tryptophan
indoleamine 2,3-dioxygenase (hIDO)	Homo sapiens	1-methyl-L-tryptophan	0.027	0.15	0.18 calc.	pH 8	PMID 19275153	Open record: indoleamine 2,3-dioxygenase (hIDO), 1-methyl-L-tryptophan
indoleamine 2,3-dioxygenase (hIDO)	Homo sapiens	1-methyl-L-tryptophan	0.064	0.062	1.0 calc.		PMID 19737010	Open record: indoleamine 2,3-dioxygenase (hIDO), 1-methyl-L-tryptophan
indoleamine 2,3-dioxygenase (hIDO)	Homo sapiens	D-tryptophan	5.9	2.6	2.3 calc.		PMID 19737010	Open record: indoleamine 2,3-dioxygenase (hIDO), D-tryptophan
indoleamine 2,3-dioxygenase (hIDO)	Homo sapiens	dioxygen	2.9	0.042	69 calc.		PMID 19737010	Open record: indoleamine 2,3-dioxygenase (hIDO), dioxygen
indoleamine 2,3-dioxygenase (hIDO)	Homo sapiens	L-tryptophanair-saturated; cosubstrate O2 (air-saturated)	3.1	0.015	210 calc.		PMID 19737010	Open record: indoleamine 2,3-dioxygenase (hIDO), L-tryptophan
indoleamine 2,3-dioxygenase (hIDO)	Homo sapiens	L-tryptophanwith 2.5 mM 3-indole ethanol (IDE, effector); cosubstrate O2	3.2	0.016	200 calc.		PMID 19737010	Open record: indoleamine 2,3-dioxygenase (hIDO), L-tryptophan
indoleamine 2,3-dioxygenase (hIDO)	Homo sapiens	L-tryptophanwith 5.1 mM 3-indole ethanol (IDE, effector); cosubstrate O2	3.5	0.015	230 calc.		PMID 19737010	Open record: indoleamine 2,3-dioxygenase (hIDO), L-tryptophan
indoleamine 2,3-dioxygenase (hIDO)	Homo sapiens	L-tryptophan	1.4	—	—		PMID 41640298	Open record: indoleamine 2,3-dioxygenase (hIDO), L-tryptophan
indoleamine 2,3-dioxygenase (hIDO)variant S167A	Homo sapiens	1-methyl-L-tryptophan	0.032	0.031	1.0 calc.	pH 8	PMID 19275153	Open record: indoleamine 2,3-dioxygenase (hIDO) variant S167A, 1-methyl-L-tryptophan
indoleamine 2,3-dioxygenase (IDO)	Branchiostoma floridae	L-tryptophan	1.377	55.4	0.025	pH 7.5, 37 °C	PMID 25702628	Open record: indoleamine 2,3-dioxygenase (IDO), L-tryptophan
indoleamine 2,3-dioxygenase (IDO)	Homo sapiens	D-tryptophanGST fusion (N-terminal GST; pGEX 4T-3	11.76	4.576	2.57	pH 6.5, 37 °C	PMID 18026683	Open record: indoleamine 2,3-dioxygenase (IDO), D-tryptophan
indoleamine 2,3-dioxygenase (IDO)	Homo sapiens	D-tryptophan	8.883	4.605	1.93	pH 6.5, 37 °C	PMID 18026683	Open record: indoleamine 2,3-dioxygenase (IDO), D-tryptophan
indoleamine 2,3-dioxygenase (IDO)	Homo sapiens	L-tryptophanGST fusion (N-terminal GST; pGEX 4T-3	7.500	0.01815	413.2	pH 6.5, 37 °C	PMID 18026683	Open record: indoleamine 2,3-dioxygenase (IDO), L-tryptophan
indoleamine 2,3-dioxygenase (IDO)	Homo sapiens	L-tryptophan	6.062	0.02123	285.5	pH 6.5, 37 °C	PMID 18026683	Open record: indoleamine 2,3-dioxygenase (IDO), L-tryptophan
indoleamine 2,3-dioxygenase (IDO)	Monosiga brevicollis	L-tryptophan	2.355	42.74	0.055	pH 7, 37 °C	PMID 25702628	Open record: indoleamine 2,3-dioxygenase (IDO), L-tryptophan
indoleamine 2,3-dioxygenase (IDO)	Mus musculus	D-tryptophan	13.65	2.87	4.75	pH 6.5, 37 °C	PMID 18026683	Open record: indoleamine 2,3-dioxygenase (IDO), D-tryptophan
indoleamine 2,3-dioxygenase (IDO)	Mus musculus	L-tryptophan	11.90	0.0281	423.5	pH 6.5, 37 °C	PMID 18026683	Open record: indoleamine 2,3-dioxygenase (IDO), L-tryptophan
indoleamine 2,3-dioxygenase (IDO)	Nematostella vectensis	L-tryptophan	1	3.2	0.312	pH 7.5, 37 °C	PMID 25702628	Open record: indoleamine 2,3-dioxygenase (IDO), L-tryptophan
indoleamine 2,3-dioxygenase (IDO, proto-IDO)	Danio rerio	L-tryptophan	2.628	28.15	0.0933	pH 6.5, 37 °C	PMID 18026683	Open record: indoleamine 2,3-dioxygenase (IDO, proto-IDO), L-tryptophan
indoleamine 2,3-dioxygenase (IDO, proto-IDO)	Xenopus laevis	L-tryptophan	2.223	11.69	0.19	pH 6.5, 37 °C	PMID 18026683	Open record: indoleamine 2,3-dioxygenase (IDO, proto-IDO), L-tryptophan
indoleamine 2,3-dioxygenase (IDO; molluscan IDO-like protein, MIP)	Haliotis diversicolor	L-tryptophan	0.537	29.9	0.018	pH 7, 37 °C	PMID 25702628	Open record: indoleamine 2,3-dioxygenase (IDO; molluscan IDO-like protein, MIP), L-tryptophan
indoleamine 2,3-dioxygenase (rhIDO)	Homo sapiens	5-fluoro-DL-tryptophan	0.76	0.006	130 calc.	pH 8, 25 °C	PMID 18370401	Open record: indoleamine 2,3-dioxygenase (rhIDO), 5-fluoro-DL-tryptophan
indoleamine 2,3-dioxygenase (rhIDO)	Homo sapiens	5-hydroxy-L-tryptophan	0.025	0.017	1.5 calc.	pH 8, 25 °C	PMID 18370401	Open record: indoleamine 2,3-dioxygenase (rhIDO), 5-hydroxy-L-tryptophan
indoleamine 2,3-dioxygenase (rhIDO)	Homo sapiens	5-methyl-DL-tryptophan	3.78	0.098	39 calc.	pH 8, 25 °C	PMID 18370401	Open record: indoleamine 2,3-dioxygenase (rhIDO), 5-methyl-DL-tryptophan
indoleamine 2,3-dioxygenase (rhIDO)	Homo sapiens	D-tryptophan	3.93	1.57	2.50 calc.	pH 8, 25 °C	PMID 18370401	Open record: indoleamine 2,3-dioxygenase (rhIDO), D-tryptophan
indoleamine 2,3-dioxygenase (rhIDO)	Homo sapiens	L-tryptophan	1.4	0.007	200 calc.	pH 8, 25 °C	PMID 18370401	Open record: indoleamine 2,3-dioxygenase (rhIDO), L-tryptophan
indoleamine 2,3-dioxygenase (S. cerevisiae IDO, BNA2 gene product)	Saccharomyces cerevisiae	D-tryptophan	1.683	9.2	1.4	pH 6.5, 37 °C	PMID 21170645	Open record: indoleamine 2,3-dioxygenase (S. cerevisiae IDO, BNA2 gene product), D-tryptophan
indoleamine 2,3-dioxygenase (S. cerevisiae IDO, BNA2 gene product)	Saccharomyces cerevisiae	L-tryptophan	8.247	0.412	20	pH 6.5, 37 °C	PMID 21170645	Open record: indoleamine 2,3-dioxygenase (S. cerevisiae IDO, BNA2 gene product), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	dioxygenfixed [L-Trp] = 8.33 µM; O2 varied 11.5-230 µM (Fig. 2B)	3.7	0.0237	150	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	dioxygenfixed [L-Trp] = 10.0 µM; O2 varied 11.5-230 µM (Fig. 2B)	4.2	0.024	170	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	dioxygenfixed [L-Trp] = 13.3 µM; O2 varied 11.5-230 µM (Fig. 2B)	4.1	0.0142	280	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	dioxygenfixed [L-Trp] = 16.7 µM; O2 varied 11.5-230 µM (Fig. 2B)	4.4	0.0115	380	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	dioxygenfixed [L-Trp] = 20.0 µM; O2 varied 11.5-230 µM (Fig. 2B)	4.8	0.014	340	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	dioxygenfixed [L-Trp] = 50.0 µM; O2 varied 4.6-348 µM (Fig. 2B)	5.8	0.0186	310	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), dioxygen
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5	8.2	0.019	430 calc.	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 20 mM ascorbate; 10 µM methylene blue	8.7	0.028	310 calc.	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 20 mM ascorbate; 10 µM methylene blue	8.9	0.029	310 calc.	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5	7.1	0.0211	330	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5	8.5	0.024	350	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5	8.5	0.0207	410	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5	8.9	0.0201	440	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5	9.7	0.0234	410	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5	10.3	0.0256	400	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (hIDO1)	Homo sapiens	L-tryptophanreducing system 150 µM beta-NADH; 1.0 µM cytochrome b5	8.3	0.019	440	pH 7, 25 °C	PMID 25712221	Open record: indoleamine 2,3-dioxygenase 1 (hIDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (IDO1)	Homo sapiens	L-tryptophan	2.17	0.0079	314	pH 6.5, 25 °C	PMID 41804238	Open record: indoleamine 2,3-dioxygenase 1 (IDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (IDO1)	Mus musculus	L-tryptophan	14.54	0.0158	920	pH 7	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 1 (IDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (IDO1)variant S171T	Mus musculus	L-tryptophan	6.577	0.0713	92	pH 7	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 1 (IDO1) variant S171T, L-tryptophan
indoleamine 2,3-dioxygenase 1 (IDO1)	Ornithorhynchus anatinus	L-tryptophan	4.27	0.0225	190	pH 8	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 1 (IDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (IDO1)variant S171T	Ornithorhynchus anatinus	L-tryptophan	4.562	0.0631	72	pH 8	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 1 (IDO1) variant S171T, L-tryptophan
indoleamine 2,3-dioxygenase 1 (IDO1)	Oryzias latipes	L-tryptophan	4.175	0.3511	12	pH 7.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 1 (IDO1), L-tryptophan
indoleamine 2,3-dioxygenase 1 (IDO1)variant S175T	Oryzias latipes	L-tryptophan	2.555	5.205	0.492	pH 7	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 1 (IDO1) variant S175T, L-tryptophan
indoleamine 2,3-dioxygenase 2 (Chicken IDO2)	Gallus gallus	L-tryptophan	0.62	4.1	0.152	pH 6.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Chicken IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (Chicken IDO2)	Gallus gallus	L-tryptophan	0.73	2.3	0.312	pH 7.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Chicken IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (Fish IDO2)	Danio rerio	L-tryptophan	1.155	37	0.032	pH 6.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Fish IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (Fish IDO2)	Danio rerio	L-tryptophan	1.65	33.9	0.048	pH 7.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Fish IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (Frog IDO2)	Xenopus laevis	L-tryptophan	2.202	12.5	0.177	pH 6.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Frog IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (Frog IDO2)	Xenopus laevis	L-tryptophan	2.332	7.4	0.315	pH 7.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Frog IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)	Anolis carolinensis	L-tryptophan	0.158	0.0814	1.945	pH 6.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)variant S171T	Anolis carolinensis	L-tryptophan	0.873	0.6002	1.455	pH 6.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant S171T, L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)	Gallus gallus	L-tryptophan	0.895	1.842	0.485	pH 8	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)variant T171S	Gallus gallus	L-tryptophan	0.665	0.4687	1.418	pH 8	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant T171S, L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)variant T171S	Mus musculus	L-tryptophan	2.89	9.4	0.307	pH 7	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant T171S, L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)variant T171S	Ornithorhynchus anatinus	L-tryptophan	4.208	12.36	0.34	pH 7.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant T171S, L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)	Oryzias latipes	L-tryptophan	1.133	24.67	0.046	pH 7.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)variant T168S	Oryzias latipes	L-tryptophan	1.858	7.83	0.237	pH 7.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant T168S, L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)	Pelodiscus sinensis	L-tryptophan	0.75	10.14	0.073	pH 7.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)variant T171S	Pelodiscus sinensis	L-tryptophan	1.112	2.464	0.45	pH 7.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant T171S, L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)	Xenopus laevis	L-tryptophan	2.493	7.313	0.342	pH 7.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (IDO2)variant T163S	Xenopus laevis	L-tryptophan	2.927	2.344	1.248	pH 7.5	PMID 25950090	Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant T163S, L-tryptophan
indoleamine 2,3-dioxygenase 2 (Opossum IDO2)	opossum	L-tryptophan	0.953	46.6	0.02	pH 6.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Opossum IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (Opossum IDO2)	opossum	L-tryptophan	0.785	21.2	0.037	pH 7.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Opossum IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (Platypus IDO2)	Ornithorhynchus anatinus	L-tryptophan	6.643	62.8	0.105	pH 6.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Platypus IDO2), L-tryptophan
indoleamine 2,3-dioxygenase 2 (Platypus IDO2)	Ornithorhynchus anatinus	L-tryptophan	6.127	47.5	0.128	pH 7.5, 37 °C	PMID 20399882	Open record: indoleamine 2,3-dioxygenase 2 (Platypus IDO2), L-tryptophan
indoleamine 2,3-dioxygenase IDOα	Aspergillus oryzae	D-tryptophan	0.365	5.8	0.063	pH 6.5, 37 °C	PMID 21170645	Open record: indoleamine 2,3-dioxygenase IDOα, D-tryptophan
indoleamine 2,3-dioxygenase IDOα	Aspergillus oryzae	L-tryptophan	0.84	0.154	5	pH 6.5, 37 °C	PMID 21170645	Open record: indoleamine 2,3-dioxygenase IDOα, L-tryptophan
indoleamine 2,3-dioxygenase IDOβ (fully spliced isoform)	Aspergillus oryzae	D-tryptophan	6.227	40.2	0.153	pH 7.5, 37 °C	PMID 21170645	Open record: indoleamine 2,3-dioxygenase IDOβ (fully spliced isoform), D-tryptophan
indoleamine 2,3-dioxygenase IDOβ (fully spliced isoform)	Aspergillus oryzae	L-tryptophan	31.89	1.4	22.7	pH 7.5, 37 °C	PMID 21170645	Open record: indoleamine 2,3-dioxygenase IDOβ (fully spliced isoform), L-tryptophan
indoleamine 2,3-dioxygenase IDOβ+ (splice isoform retaining the first intron, 447 aa)	Aspergillus oryzae	D-tryptophan	0.095	25.4	0.0033	pH 7.5, 37 °C	PMID 21170645	Open record: indoleamine 2,3-dioxygenase IDOβ+ (splice isoform retaining the first intron, 447 aa), D-tryptophan
indoleamine 2,3-dioxygenase IDOβ+ (splice isoform retaining the first intron, 447 aa)	Aspergillus oryzae	L-tryptophan	5.41	20.8	0.27	pH 7.5, 37 °C	PMID 21170645	Open record: indoleamine 2,3-dioxygenase IDOβ+ (splice isoform retaining the first intron, 447 aa), L-tryptophan
indoleamine 2,3-dioxygenase-1 (IDO1)	Homo sapiens	1-methyl-D-tryptophan	0.095	0.66	0.14 calc.	pH 6.5, 25 °C	PMID 24875753	Open record: indoleamine 2,3-dioxygenase-1 (IDO1), 1-methyl-D-tryptophan
indoleamine 2,3-dioxygenase-1 (IDO1)	Homo sapiens	1-methyl-L-tryptophan	0.062	0.07	0.89 calc.	pH 6.5, 25 °C	PMID 24875753	Open record: indoleamine 2,3-dioxygenase-1 (IDO1), 1-methyl-L-tryptophan
indoleamine 2,3-dioxygenase-1 (IDO1)	Homo sapiens	D-tryptophan	2.7	0.296	9.1 calc.	pH 6.5, 25 °C	PMID 24875753	Open record: indoleamine 2,3-dioxygenase-1 (IDO1), D-tryptophan
indoleamine 2,3-dioxygenase-1 (IDO1)	Homo sapiens	L-tryptophan	2.97	0.0209	142 calc.	pH 6.5, 25 °C	PMID 24875753	Open record: indoleamine 2,3-dioxygenase-1 (IDO1), L-tryptophan
molluscan IDO-like protein (MIP-II)	Sulculus diversicolor	L-tryptophan	0.4068	42.66	0.0095	pH 6.5, 37 °C	PMID 18026683	Open record: molluscan IDO-like protein (MIP-II), L-tryptophan