Values CatLog read from this paper
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
PMID 41804238doi:10.1111/febs.70476Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (24 values) from this paper: indoleamine 2,3-dioxygenase 2 (IDO2), indoleamine 2,3-dioxygenase 1 (IDO1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| indoleamine 2,3-dioxygenase 1 (IDO1) | Homo sapiens | L-tryptophan | 2.17 | 0.0079 | 314 | pH 6.5, 25 °C | Open record: indoleamine 2,3-dioxygenase 1 (IDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase 2 (IDO2) | Homo sapiens | 5-methoxy-L-tryptophan | 0.648 | 0.311 | 2.69 | pH 7.4, 25 °C | Open record: indoleamine 2,3-dioxygenase 2 (IDO2), 5-methoxy-L-tryptophan |
| indoleamine 2,3-dioxygenase 2 (IDO2) | Homo sapiens | 5-methyl-L-tryptophan | 0.449 | 0.0446 | 13.7 | pH 7.4, 25 °C | Open record: indoleamine 2,3-dioxygenase 2 (IDO2), 5-methyl-L-tryptophan |
| indoleamine 2,3-dioxygenase 2 (IDO2) | Homo sapiens | L-tryptophanN-terminally truncated (Δ13); residues 14-420 | 0.239 | 2.1 | 0.125 | pH 7.4, 25 °C | Open record: indoleamine 2,3-dioxygenase 2 (IDO2), L-tryptophan |
| indoleamine 2,3-dioxygenase 2 (IDO2) | Homo sapiens | L-tryptophan | 0.39 | 1.792 | 0.22 | pH 7.4, 25 °C | Open record: indoleamine 2,3-dioxygenase 2 (IDO2), L-tryptophan |
| indoleamine 2,3-dioxygenase 2 (IDO2)variant H143Y | Homo sapiens | 5-methoxy-L-tryptophan | 0.237 | 0.0256 | 22.3 | pH 7.4, 25 °C | Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant H143Y, 5-methoxy-L-tryptophan |
| indoleamine 2,3-dioxygenase 2 (IDO2)variant H143Y | Homo sapiens | 5-methyl-L-tryptophan | 0.89 | 0.289 | 4.98 | pH 7.4, 25 °C | Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant H143Y, 5-methyl-L-tryptophan |
| indoleamine 2,3-dioxygenase 2 (IDO2)variant H143Y | Homo sapiens | L-tryptophan | 0.758 | 0.0056 | 161 | pH 7.4, 25 °C | Open record: indoleamine 2,3-dioxygenase 2 (IDO2) variant H143Y, L-tryptophan |