Values CatLog read from this paper
A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase
PMID 18370401doi:10.1021/bi702393bOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (15 values) from this paper: indoleamine 2,3-dioxygenase (rhIDO), tryptophan 2,3-dioxygenase (rhTDO) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 7 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| indoleamine 2,3-dioxygenase (rhIDO) | Homo sapiens | 5-fluoro-DL-tryptophan | 0.76 | 0.006 | 130 calc. | pH 8, 25 °C | Open record: indoleamine 2,3-dioxygenase (rhIDO), 5-fluoro-DL-tryptophan |
| indoleamine 2,3-dioxygenase (rhIDO) | Homo sapiens | 5-hydroxy-L-tryptophan | 0.025 | 0.017 | 1.5 calc. | pH 8, 25 °C | Open record: indoleamine 2,3-dioxygenase (rhIDO), 5-hydroxy-L-tryptophan |
| indoleamine 2,3-dioxygenase (rhIDO) | Homo sapiens | 5-methyl-DL-tryptophan | 3.78 | 0.098 | 39 calc. | pH 8, 25 °C | Open record: indoleamine 2,3-dioxygenase (rhIDO), 5-methyl-DL-tryptophan |
| indoleamine 2,3-dioxygenase (rhIDO) | Homo sapiens | D-tryptophan | 3.93 | 1.57 | 2.50 calc. | pH 8, 25 °C | Open record: indoleamine 2,3-dioxygenase (rhIDO), D-tryptophan |
| indoleamine 2,3-dioxygenase (rhIDO) | Homo sapiens | L-tryptophan | 1.4 | 0.007 | 200 calc. | pH 8, 25 °C | Open record: indoleamine 2,3-dioxygenase (rhIDO), L-tryptophan |
| tryptophan 2,3-dioxygenase (rhTDO) | Homo sapiens | 5-fluoro-DL-tryptophan | 0.18 | 0.36 | 0.50 calc. | pH 8, 25 °C | Open record: tryptophan 2,3-dioxygenase (rhTDO), 5-fluoro-DL-tryptophan |
| tryptophan 2,3-dioxygenase (rhTDO) | Homo sapiens | 5-methyl-DL-tryptophan | — | — | 0.1 | pH 8, 25 °C | Open record: tryptophan 2,3-dioxygenase (rhTDO), 5-methyl-DL-tryptophan |
| tryptophan 2,3-dioxygenase (rhTDO) | Homo sapiens | L-tryptophan | 1.4 | 0.222 | 6.3 calc. | pH 8, 25 °C | Open record: tryptophan 2,3-dioxygenase (rhTDO), L-tryptophan |