Values CatLog read from this paper
Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1
PMID 24875753doi:10.1007/s00726-014-1766-3Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (32 values) from this paper: indoleamine 2,3-dioxygenase-2 (IDO2), indoleamine 2,3-dioxygenase-1 (IDO1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 4 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| indoleamine 2,3-dioxygenase-1 (IDO1) | Homo sapiens | 1-methyl-D-tryptophan | 0.095 | 0.66 | 0.14 calc. | pH 6.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-1 (IDO1), 1-methyl-D-tryptophan |
| indoleamine 2,3-dioxygenase-1 (IDO1) | Homo sapiens | 1-methyl-L-tryptophan | 0.062 | 0.07 | 0.89 calc. | pH 6.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-1 (IDO1), 1-methyl-L-tryptophan |
| indoleamine 2,3-dioxygenase-1 (IDO1) | Homo sapiens | D-tryptophan | 2.7 | 0.296 | 9.1 calc. | pH 6.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-1 (IDO1), D-tryptophan |
| indoleamine 2,3-dioxygenase-1 (IDO1) | Homo sapiens | L-tryptophan | 2.97 | 0.0209 | 142 calc. | pH 6.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-1 (IDO1), L-tryptophan |
| indoleamine 2,3-dioxygenase-2 (IDO2) | Homo sapiens | 1-methyl-D-tryptophan | 0.0052 | 0.747 | 0.007 | pH 7.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-2 (IDO2), 1-methyl-D-tryptophan |
| indoleamine 2,3-dioxygenase-2 (IDO2) | Homo sapiens | 1-methyl-L-tryptophan | 0.011 | 0.696 | 0.016 | pH 7.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-2 (IDO2), 1-methyl-L-tryptophan |
| indoleamine 2,3-dioxygenase-2 (IDO2) | Homo sapiens | 5-fluoro-D,L-tryptophan | 0.049 | 1.768 | 0.028 | pH 7.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-2 (IDO2), 5-fluoro-D,L-tryptophan |
| indoleamine 2,3-dioxygenase-2 (IDO2) | Homo sapiens | 5-methoxy-D,L-tryptophan | 0.161 | 0.547 | 0.294 | pH 7.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-2 (IDO2), 5-methoxy-D,L-tryptophan |
| indoleamine 2,3-dioxygenase-2 (IDO2) | Homo sapiens | 5-methyl-D,L-tryptophan | 0.36 | 1.57 | 0.229 | pH 7.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-2 (IDO2), 5-methyl-D,L-tryptophan |
| indoleamine 2,3-dioxygenase-2 (IDO2) | Homo sapiens | 6-methyl-D,L-tryptophan | 0.108 | 3.457 | 0.031 | pH 7.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-2 (IDO2), 6-methyl-D,L-tryptophan |
| indoleamine 2,3-dioxygenase-2 (IDO2) | Homo sapiens | D-tryptophan | 0.0103 | 3.609 | 0.0028 | pH 7.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-2 (IDO2), D-tryptophan |
| indoleamine 2,3-dioxygenase-2 (IDO2) | Homo sapiens | L-tryptophan | 0.103 | 6.809 | 0.015 | pH 7.5, 25 °C | Open record: indoleamine 2,3-dioxygenase-2 (IDO2), L-tryptophan |