Values CatLog read from this paper
SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2
PMID 32457458doi:10.1038/s41598-020-65351-zOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (20 values) from this paper: IDH2 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 10 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| IDH2 | Homo sapiens | isocitrate | 15.5 | 0.005 | 3.1 × 10³ calc. | pH 8, 37 °C | Open record: IDH2, isocitrate |
| IDH2 | Homo sapiens | isocitratecells co-transfected with SIRT3 WT | 11.3 | 0.0039 | 2.9 × 10³ calc. | pH 8, 37 °C | Open record: IDH2, isocitrate |
| IDH2 | Homo sapiens | isocitratecells co-transfected with inactive SIRT3 H248Y | 12.3 | 0.0052 | 2.4 × 10³ calc. | pH 8, 37 °C | Open record: IDH2, isocitrate |
| IDH2 | Homo sapiens | isocitrateIDH2-overexpressing SHSY5Y cells transfected with GCN5L | 21 | 0.005 | 4.2 × 10³ calc. | pH 8, 37 °C | Open record: IDH2, isocitrate |
| IDH2 | Homo sapiens | NADP+ | 23.5 | 0.0176 | 1.34 × 10³ calc. | pH 8, 37 °C | Open record: IDH2, NADP+ |
| IDH2 | Homo sapiens | NADP+cells co-transfected with SIRT3 WT | 19.2 | 0.0119 | 1.61 × 10³ calc. | pH 8, 37 °C | Open record: IDH2, NADP+ |
| IDH2 | Homo sapiens | NADP+cells co-transfected with inactive SIRT3 H248Y | 21.9 | 0.0177 | 1.24 × 10³ calc. | pH 8, 37 °C | Open record: IDH2, NADP+ |
| IDH2 | Homo sapiens | NADP+IDH2-overexpressing SHSY5Y cells transfected with GCN5L | 26.6 | 0.0126 | 2.11 × 10³ calc. | pH 8, 37 °C | Open record: IDH2, NADP+ |
| IDH2variant K413Q | Homo sapiens | isocitrate | 4.9 | 0.003 | 1.6 × 10³ calc. | pH 8, 37 °C | Open record: IDH2 variant K413Q, isocitrate |
| IDH2variant K413Q | Homo sapiens | NADP+ | 7.9 | 0.0569 | 140 calc. | pH 8, 37 °C | Open record: IDH2 variant K413Q, NADP+ |