Values CatLog read from this paper
Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors
PMID 26242695doi:10.1111/cbdd.12630Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 7 records (21 values) from this paper: adenosine kinase from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| adenosine kinase | Homo sapiens | adenosine | 0.5 | 4 × 10⁻⁴ | 1.25 × 10³ | pH 7.5, 37 °C | Open record: adenosine kinase, adenosine |
| adenosine kinasevariant F338A | Homo sapiens | adenosine | 0.08 | 8.3 × 10⁻⁴ | 100 | pH 7.5, 37 °C | Open record: adenosine kinase variant F338A, adenosine |
| adenosine kinasevariant H107A | Homo sapiens | adenosine | 0.35 | 0.00166 | 270 | pH 7.5, 37 °C | Open record: adenosine kinase variant H107A, adenosine |
| adenosine kinasevariant K341A | Homo sapiens | adenosine | 0.22 | 1.7 × 10⁻⁴ | 1.29 × 10³ | pH 7.5, 37 °C | Open record: adenosine kinase variant K341A, adenosine |
| adenosine kinasevariant Q74A | Homo sapiens | adenosine | 0.05 | 4.8 × 10⁻⁴ | 100 | pH 7.5, 37 °C | Open record: adenosine kinase variant Q74A, adenosine |
| adenosine kinasevariant Q74A/F338A | Homo sapiens | adenosine | 0.02 | 3.6 × 10⁻⁴ | 50 | pH 7.5, 37 °C | Open record: adenosine kinase variant Q74A/F338A, adenosine |
| adenosine kinasevariant Q78A | Homo sapiens | adenosine | 0.05 | 3.9 × 10⁻⁴ | 130 | pH 7.5, 37 °C | Open record: adenosine kinase variant Q78A, adenosine |