EC 2.7.1.20: adenosine kinase

TransferasesOpen in Browse

CatLog read 76 records for EC 2.7.1.20 from 8 papers, for 8 organisms. Names in these papers: adenosine kinase, adenosine kinase (TbAK), ZmADK2 (adenosine kinase), adenosine kinase (LdAdK) and 4 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 49 records for EC 2.7.1.20 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.1.20 in Browse.

Papers

Papers with records for EC 2.7.1.20
Paper	Organisms	Records
A monomer-dimer switch modulates the activity of plant adenosine kinase	Physcomitrella patens, Zea mays	19
Adenosine kinase mediates high affinity adenosine salvage in Trypanosoma brucei	Trypanosoma brucei	16
Mutational analysis of the active-site residues crucial for catalytic activity of adenosine kinase from Leishmania donovani	Leishmania donovani	11
A high-affinity adenosine kinase from Anopheles gambiae	Anopheles gambiae	10
Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors	Homo sapiens	7
A broad specificity nucleoside kinase from Thermoplasma acidophilum	Thermoplasma acidophilum	6
Phosphorylation of ribavirin and viramidine by adenosine kinase and cytosolic 5'-nucleotidase II: Implications for ribavirin metabolism in erythrocytes	Chinese hamster	5
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metabolite	Homo sapiens	2

Records

Records for EC 2.7.1.20 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
adenosine kinase	Anopheles gambiae	adenosine27 °C radiometric assay; cosubstrate ATP (fixed)	0.16	8.1 × 10⁻⁶	1.97 × 10⁴	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, adenosine
adenosine kinase	Anopheles gambiae	adenosineadenosine varied; GTP fixed (footnote a: 100 μM NTP)	0.63	2.3 × 10⁻⁴	2.7 × 10³	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, adenosine
adenosine kinase	Anopheles gambiae	adenosineadenosine varied; UTP fixed (footnote a: 100 μM NTP)	0.035	7.4 × 10⁻⁴	4.7 × 10³	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, adenosine
adenosine kinase	Anopheles gambiae	adenosineadenosine varied; CTP fixed (footnote a: 100 μM NTP)	0.029	6.3 × 10⁻⁴	4.6 × 10³	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, adenosine
adenosine kinase	Anopheles gambiae	adenosineadenosine varied; TTP fixed (footnote a: 100 μM NTP)	0.056	7.9 × 10⁻⁴	7.1 × 10³	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, adenosine
adenosine kinase	Anopheles gambiae	adenosine 5'-triphosphate	0.33	0.0014	240	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, adenosine 5'-triphosphate
adenosine kinase	Anopheles gambiae	cytidine 5'-triphosphate	0.062	0.049	1.27	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, cytidine 5'-triphosphate
adenosine kinase	Anopheles gambiae	guanosine 5'-triphosphate	1.39	0.054	26	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, guanosine 5'-triphosphate
adenosine kinase	Anopheles gambiae	thymidine 5'-triphosphate	0.3	0.245	1.2	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, thymidine 5'-triphosphate
adenosine kinase	Anopheles gambiae	uridine 5'-triphosphate	0.061	0.056	1.09	pH 7.4, 27 °C	PMID 21247194	Open record: adenosine kinase, uridine 5'-triphosphate
adenosine kinase	Chinese hamster	1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide1x Dulbecco's PBS; 1.5 mM MgCl2	0.03	0.54	0.055	pH 7.3, 37 °C	PMID 15917509	Open record: adenosine kinase, 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
adenosine kinase	Chinese hamster	1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide100 mM HEPES replacing PBS	0.0103	7.8	0.00132	pH 7.3, 37 °C	PMID 15917509	Open record: adenosine kinase, 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
adenosine kinase	Chinese hamster	1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine	0.0027	16	1.7 × 10⁻⁴	pH 7.3, 37 °C	PMID 15917509	Open record: adenosine kinase, 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine
adenosine kinase	Chinese hamster	1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine	0.0043	7.7	5.7 × 10⁻⁴	pH 9, 37 °C	PMID 15917509	Open record: adenosine kinase, 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine
adenosine kinase	Chinese hamster	adenosine	0.22	0.0032	65	pH 7.3, 37 °C	PMID 15917509	Open record: adenosine kinase, adenosine
adenosine kinase	Homo sapiens	adenosine	0.5	4 × 10⁻⁴	1.25 × 10³	pH 7.5, 37 °C	PMID 26242695	Open record: adenosine kinase, adenosine
adenosine kinasevariant F338A	Homo sapiens	adenosine	0.08	8.3 × 10⁻⁴	100	pH 7.5, 37 °C	PMID 26242695	Open record: adenosine kinase variant F338A, adenosine
adenosine kinasevariant H107A	Homo sapiens	adenosine	0.35	0.00166	270	pH 7.5, 37 °C	PMID 26242695	Open record: adenosine kinase variant H107A, adenosine
adenosine kinasevariant K341A	Homo sapiens	adenosine	0.22	1.7 × 10⁻⁴	1.29 × 10³	pH 7.5, 37 °C	PMID 26242695	Open record: adenosine kinase variant K341A, adenosine
adenosine kinasevariant Q74A	Homo sapiens	adenosine	0.05	4.8 × 10⁻⁴	100	pH 7.5, 37 °C	PMID 26242695	Open record: adenosine kinase variant Q74A, adenosine
adenosine kinasevariant Q74A/F338A	Homo sapiens	adenosine	0.02	3.6 × 10⁻⁴	50	pH 7.5, 37 °C	PMID 26242695	Open record: adenosine kinase variant Q74A/F338A, adenosine
adenosine kinasevariant Q78A	Homo sapiens	adenosine	0.05	3.9 × 10⁻⁴	130	pH 7.5, 37 °C	PMID 26242695	Open record: adenosine kinase variant Q78A, adenosine
adenosine kinase (ADK)	Homo sapiens	adenosine	0.237	7.2 × 10⁻⁴	330	pH 7.5	PMID 42363837	Open record: adenosine kinase (ADK), adenosine
adenosine kinase (ADK)	Homo sapiens	GS-441524	5.5 × 10⁻⁵	0.193	2.85 × 10⁻⁴	pH 7.5	PMID 42363837	Open record: adenosine kinase (ADK), GS-441524
adenosine kinase (LdAdK)	Leishmania donovani	adenosine	1.43	0.02	72	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK), adenosine
adenosine kinase (LdAdK)	Leishmania donovani	adenosine 5'-triphosphate	1.2	0.042	28.5	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK), adenosine 5'-triphosphate
adenosine kinase (LdAdK)variant G62D	Leishmania donovani	adenosine 5'-triphosphate	0.0033	0.139	0.017	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK) variant G62D, adenosine 5'-triphosphate
adenosine kinase (LdAdK)variant R131A	Leishmania donovani	adenosine	0.065	0.016	4	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK) variant R131A, adenosine
adenosine kinase (LdAdK)variant R131A	Leishmania donovani	adenosine 5'-triphosphate	0.052	0.071	0.72	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK) variant R131A, adenosine 5'-triphosphate
adenosine kinase (LdAdK)variant R69A	Leishmania donovani	adenosine	0.038	0.015	2.55	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK) variant R69A, adenosine
adenosine kinase (LdAdK)variant R69A	Leishmania donovani	adenosine 5'-triphosphate	0.0292	0.068	0.42	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK) variant R69A, adenosine 5'-triphosphate
adenosine kinase (LdAdK)variant R69K	Leishmania donovani	adenosine	0.043	0.017	2.55	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK) variant R69K, adenosine
adenosine kinase (LdAdK)variant R69K	Leishmania donovani	adenosine 5'-triphosphate	0.0323	0.278	0.12	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK) variant R69K, adenosine 5'-triphosphate
adenosine kinase (LdAdK)variant R69K/R131A	Leishmania donovani	adenosine	0.0062	0.016	0.38	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK) variant R69K/R131A, adenosine
adenosine kinase (LdAdK)variant R69K/R131A	Leishmania donovani	adenosine 5'-triphosphate	0.0077	1.282	0.0067	30 °C	PMID 15606359	Open record: adenosine kinase (LdAdK) variant R69K/R131A, adenosine 5'-triphosphate
adenosine kinase (TbAK)	Trypanosoma brucei	2'-deoxyadenosine5 mM potassium phosphate	4.2	0.11	38	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), 2'-deoxyadenosine
adenosine kinase (TbAK)	Trypanosoma brucei	2'-deoxyadenosine0 mM potassium phosphate	—	0.11	—	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), 2'-deoxyadenosine
adenosine kinase (TbAK)	Trypanosoma brucei	2'-deoxyadenosine50 mM potassium phosphate	—	0.19	—	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), 2'-deoxyadenosine
adenosine kinase (TbAK)	Trypanosoma brucei	3'-deoxyadenosine5 mM potassium phosphate	3.9	0.013	300	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), 3'-deoxyadenosine
adenosine kinase (TbAK)	Trypanosoma brucei	3'-deoxyadenosine50 mM potassium phosphate	—	0.032	—	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), 3'-deoxyadenosine
adenosine kinase (TbAK)	Trypanosoma brucei	adenosine5 mM potassium phosphate	8.1	4.1 × 10⁻⁵	2 × 10⁵	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), adenosine
adenosine kinase (TbAK)	Trypanosoma brucei	adenosine0 mM potassium phosphate	—	4.1 × 10⁻⁵	—	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), adenosine
adenosine kinase (TbAK)	Trypanosoma brucei	adenosine50 mM potassium phosphate	—	8.5 × 10⁻⁵	—	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), adenosine
adenosine kinase (TbAK)	Trypanosoma brucei	ATP	7.3	0.026	280	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), ATP
adenosine kinase (TbAK)	Trypanosoma brucei	CTP	20	0.61	32	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), CTP
adenosine kinase (TbAK)	Trypanosoma brucei	fludarabine	0.11	0.54	0.2	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), fludarabine
adenosine kinase (TbAK)	Trypanosoma brucei	GTP	16	0.082	190	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), GTP
adenosine kinase (TbAK)	Trypanosoma brucei	inosine	1.1	0.57	2	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), inosine
adenosine kinase (TbAK)	Trypanosoma brucei	UTP	18	0.34	52	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), UTP
adenosine kinase (TbAK)	Trypanosoma brucei	vidarabine5 mM potassium phosphate	1.3	0.23	5.8	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), vidarabine
adenosine kinase (TbAK)	Trypanosoma brucei	vidarabine50 mM potassium phosphate	—	0.28	—	pH 7.6, 37 °C	PMID 18167353	Open record: adenosine kinase (TbAK), vidarabine
nucleoside kinase TaNK (Ta0880)	Thermoplasma acidophilum	adenosine	0.084	0.00112	74.9	pH 8, 22 °C	PMID 23161756	Open record: nucleoside kinase TaNK (Ta0880), adenosine
nucleoside kinase TaNK (Ta0880)	Thermoplasma acidophilum	ATP	0.174	0.0469	3.7	pH 8, 22 °C	PMID 23161756	Open record: nucleoside kinase TaNK (Ta0880), ATP
nucleoside kinase TaNK (Ta0880)	Thermoplasma acidophilum	cytidine	0.0644	4.11 × 10⁻⁴	156	pH 8, 22 °C	PMID 23161756	Open record: nucleoside kinase TaNK (Ta0880), cytidine
nucleoside kinase TaNK (Ta0880)	Thermoplasma acidophilum	GTP	0.266	0.185	1.44	pH 8, 22 °C	PMID 23161756	Open record: nucleoside kinase TaNK (Ta0880), GTP
nucleoside kinase TaNK (Ta0880)	Thermoplasma acidophilum	guanosine	0.0719	2.08 × 10⁻⁴	345	pH 8, 22 °C	PMID 23161756	Open record: nucleoside kinase TaNK (Ta0880), guanosine
nucleoside kinase TaNK (Ta0880)	Thermoplasma acidophilum	inosine	0.16	7.12 × 10⁻⁴	215	pH 8, 22 °C	PMID 23161756	Open record: nucleoside kinase TaNK (Ta0880), inosine
PpADK1 (adenosine kinase)	Physcomitrella patens	adenosine	0.21	7.1 × 10⁻⁴	300	pH 7.5, 30 °C	PMID 40063605	Open record: PpADK1 (adenosine kinase), adenosine
PpADK1 (adenosine kinase)	Physcomitrella patens	N6-isopentenyladenosine	0.03	0.0121	2.5	pH 7.5, 30 °C	PMID 40063605	Open record: PpADK1 (adenosine kinase), N6-isopentenyladenosine
ZmADK2 (adenosine kinase)	Zea mays	2'-deoxyadenosine	0.46	0.506	0.91 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), 2'-deoxyadenosine
ZmADK2 (adenosine kinase)	Zea mays	3'-deoxyadenosine	0.43	0.173	2.5 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), 3'-deoxyadenosine
ZmADK2 (adenosine kinase)	Zea mays	7-deazaadenosine	0.17	0.0034	50 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), 7-deazaadenosine
ZmADK2 (adenosine kinase)	Zea mays	adenine arabinoside	0.24	0.524	0.46 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), adenine arabinoside
ZmADK2 (adenosine kinase)	Zea mays	adenosine	1.55	6.5 × 10⁻⁴	2.4 × 10³	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), adenosine
ZmADK2 (adenosine kinase)	Zea mays	Cytidine	0.23	0.313	0.73 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), Cytidine
ZmADK2 (adenosine kinase)	Zea mays	Guanosine	0.48	0.218	2.2 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), Guanosine
ZmADK2 (adenosine kinase)	Zea mays	Inosine	0.57	0.42	1.4 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), Inosine
ZmADK2 (adenosine kinase)	Zea mays	N6,N6-dimethyladenosine	0.2	0.0112	18 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), N6,N6-dimethyladenosine
ZmADK2 (adenosine kinase)	Zea mays	N6-isobutyladenosine	0.21	0.0704	3.0 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), N6-isobutyladenosine
ZmADK2 (adenosine kinase)	Zea mays	N6-isopentenyladenosine	0.19	0.0098	20	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), N6-isopentenyladenosine
ZmADK2 (adenosine kinase)	Zea mays	N6-isopropyladenosine	0.19	0.0548	3.5 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), N6-isopropyladenosine
ZmADK2 (adenosine kinase)	Zea mays	N6-methyladenosine	0.24	0.0107	22 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), N6-methyladenosine
ZmADK2 (adenosine kinase)	Zea mays	Uridine	0.15	—	—	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), Uridine
ZmADK2 (adenosine kinase)	Zea mays	Xanthosine	0.55	0.178	3.1 calc.	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK2 (adenosine kinase), Xanthosine
ZmADK3 (adenosine kinase)	Zea mays	adenosine	1.18	5.1 × 10⁻⁴	2.3 × 10³	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK3 (adenosine kinase), adenosine
ZmADK3 (adenosine kinase)	Zea mays	N6-isopentenyladenosine	0.22	0.0043	50	pH 7.5, 30 °C	PMID 40063605	Open record: ZmADK3 (adenosine kinase), N6-isopentenyladenosine