Values CatLog read from this paper
The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276
PMID 19351161doi:10.1021/bi9003292Open in Browse
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CatLog read 12 records (28 values) from this paper: SHV-1 β-lactamase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| SHV-1 β-lactamase | — | ampicillin | 3.1 × 10³ | 0.183 | 1.7 × 10⁴ | pH 7.4 | Open record: SHV-1 β-lactamase, ampicillin |
| SHV-1 β-lactamase | — | cephalothin | 14 | 0.029 | 470 | pH 7.4 | Open record: SHV-1 β-lactamase, cephalothin |
| SHV-1 β-lactamase | — | clavulanate | 0.6 | — | — | pH 7.4 | Open record: SHV-1 β-lactamase, clavulanate |
| SHV-1 β-lactamase | — | methylidene penem | 0.34 | — | — | pH 7.4 | Open record: SHV-1 β-lactamase, methylidene penem |
| SHV-1 β-lactamase | — | nitrocefin | 237 | 0.021 | 1.1 × 10⁴ | pH 7.4 | Open record: SHV-1 β-lactamase, nitrocefin |
| SHV-1 β-lactamase | — | piperacillin | 898 | 0.077 | 1.2 × 10⁴ | pH 7.4 | Open record: SHV-1 β-lactamase, piperacillin |
| SHV-1 β-lactamasevariant N276D | — | ampicillin | 989 | 0.134 | 7 × 10³ | pH 7.4 | Open record: SHV-1 β-lactamase variant N276D, ampicillin |
| SHV-1 β-lactamasevariant N276D | — | cephalothin | 10 | 0.083 | 120 | pH 7.4 | Open record: SHV-1 β-lactamase variant N276D, cephalothin |
| SHV-1 β-lactamasevariant N276D | — | clavulanate | 0.75 | — | — | pH 7.4 | Open record: SHV-1 β-lactamase variant N276D, clavulanate |
| SHV-1 β-lactamasevariant N276D | — | methylidene penem | 0.48 | — | — | pH 7.4 | Open record: SHV-1 β-lactamase variant N276D, methylidene penem |
| SHV-1 β-lactamasevariant N276D | — | nitrocefin | 137 | 0.028 | 5 × 10³ | pH 7.4 | Open record: SHV-1 β-lactamase variant N276D, nitrocefin |
| SHV-1 β-lactamasevariant N276D | — | piperacillin | 976 | 0.105 | 9 × 10³ | pH 7.4 | Open record: SHV-1 β-lactamase variant N276D, piperacillin |