Values CatLog read from this paper

A single residue in leucyl-tRNA synthetase affecting amino acid specificity and tRNA aminoacylation

PMID 17378584doi:10.1021/bi0618215Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 31 records (93 values) from this paper: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS), Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) from Homo sapiens, Escherichia coli.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 6.1.1.4

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)	Escherichia coli	Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)	14.5	4 × 10⁻⁴	3.6 × 10⁴	pH 7, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS), Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)	Escherichia coli	human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)	0.0016	0.025	0.0064	pH 7, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS), human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)	Escherichia coli	isoleucine	0.51	0.14	3.6	pH 7.5, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS), isoleucine
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)	Escherichia coli	leucine	29	0.013	2.2 × 10³	pH 7.5, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS), leucine
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570F	Escherichia coli	Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)	24	0.0029	8 × 10³	pH 7, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570F, Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570F	Escherichia coli	human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)	0.0029	0.0017	1.7	pH 7, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570F, human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570F	Escherichia coli	isoleucine	0.55	0.05	10.8	pH 7.5, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570F, isoleucine
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570F	Escherichia coli	leucine	35	0.15	230	pH 7.5, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570F, leucine
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570K	Escherichia coli	Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)	9.8	9 × 10⁻⁴	1.1 × 10⁴	pH 7, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570K, Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570K	Escherichia coli	human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)	1.8 × 10⁻⁵	0.002	0.009	pH 7, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570K, human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570K	Escherichia coli	isoleucine	0.76	1.5	0.5	pH 7.5, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570K, isoleucine
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570K	Escherichia coli	leucine	37	0.013	2.8 × 10³	pH 7.5, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570K, leucine
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570R	Escherichia coli	Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)	21	0.0015	1.4 × 10⁴	pH 7, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570R, Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570R	Escherichia coli	isoleucine	0.23	0.09	2.6	pH 7.5, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570R, isoleucine
Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS)variant L570R	Escherichia coli	leucine	43	0.003	1.43 × 10⁴	pH 7.5, 37 °C	Open record: Escherichia coli leucyl-tRNA synthetase (E. coli LeuRS) variant L570R, leucine
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)	Homo sapiens	Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)	0.39	2 × 10⁻⁴	2 × 10³	pH 7, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS), Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)	Homo sapiens	human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)	0.09	0.004	24	pH 7, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS), human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)	Homo sapiens	isoleucine	0.44	11	0.04	pH 7.5, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS), isoleucine
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)	Homo sapiens	leucine	7.9	0.15	50	pH 7.5, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS), leucine
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600F	Homo sapiens	Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)	3	0.0022	1.4 × 10³	pH 7, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600F, Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600F	Homo sapiens	human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)	0.13	0.006	20	pH 7, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600F, human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600F	Homo sapiens	isoleucine	0.5	0.9	0.58	pH 7.5, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600F, isoleucine
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600F	Homo sapiens	leucine	25	0.33	80	pH 7.5, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600F, leucine
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600L	Homo sapiens	Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)	0.35	0.0018	190	pH 7, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600L, Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600L	Homo sapiens	human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)	0.0027	0.0015	1.8	pH 7, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600L, human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600L	Homo sapiens	isoleucine	0.14	11	0.013	pH 7.5, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600L, isoleucine
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600L	Homo sapiens	leucine	5.9	0.03	200	pH 7.5, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600L, leucine
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600R	Homo sapiens	Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)	3.2	0.0013	1.8 × 10³	pH 7, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600R, Escherichia coli tRNALeu(CUN) (T7 in vitro transcript)
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600R	Homo sapiens	human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)	0.14	0.004	30	pH 7, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600R, human mitochondrial tRNALeu(UUR) (T7 in vitro transcript)
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600R	Homo sapiens	isoleucine	0.52	1.1	0.49	pH 7.5, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600R, isoleucine
human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS)variant K600R	Homo sapiens	leucine	27	0.07	420	pH 7.5, 37 °C	Open record: human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) variant K600R, leucine