Values CatLog read from this paper
Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics
PMID 19804409doi:10.1111/j.1742-4658.2009.07337.xOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 33 records (82 values) from this paper: glutaminyl cyclase isoenzyme (isoQC) (human), glutaminyl cyclase isoenzyme (isoQC) (murine) from Homo sapiens, Mus musculus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 9 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| glutaminyl cyclase isoenzyme (isoQC) (human) | Homo sapiens | H-Gln-Glu-Asp-Leu-NH2 | — | — | 10 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human), H-Gln-Glu-Asp-Leu-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (human) | Homo sapiens | H-Gln-Glu-Tyr-Phe-NH2 | — | — | 110 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human), H-Gln-Glu-Tyr-Phe-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (human) | Homo sapiens | H-Gln-Phe-Ala-NH2 | — | — | 33 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human), H-Gln-Phe-Ala-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (human) | Homo sapiens | H-Gln-Tyr-Ala-NH2 | — | — | 66 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human), H-Gln-Tyr-Ala-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N | Homo sapiens | H-Gln-Gln-OH | 6.2 | 0.19 | 33 calc. | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N, H-Gln-Gln-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N | Homo sapiens | H-Gln-Glu-OH | 4.9 | 0.79 | 6.2 calc. | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N, H-Gln-Glu-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N | Homo sapiens | L-glutamine beta-naphthylamide | 12 | 0.058 | 210 calc. | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N, L-glutamine beta-naphthylamide |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Gln-OHstarting at Glu60 (Table 1 label prints F60 | 5.7 | 0.19 | 30 calc. | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Gln-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Gln-OHstarting at Glu60 (Table 1 label prints F60; deglycosylated | 4.6 | 0.16 | 29 calc. | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Gln-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Gln-OHC-terminal His6 tag; secreted from Pichia pastoris | 2.7 | 0.11 | 54 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Gln-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Glu-Asp-Leu-NH2 | 6.4 | 0.16 | 55 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Glu-Asp-Leu-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Glu-OHstarting at Glu60 (Table 1 label prints F60 | 4.9 | 1.1 | 4.5 calc. | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Glu-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Glu-OHstarting at Glu60 (Table 1 label prints F60; deglycosylated | 4.3 | 0.89 | 4.8 calc. | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Glu-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Glu-OHC-terminal His6 tag; secreted from Pichia pastoris | 2.6 | 0.61 | 9 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Glu-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Glu-Tyr-Phe-NH2 | 3.3 | 0.04 | 123 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Glu-Tyr-Phe-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Gly-OH | 1.65 | 0.36 | 9 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Gly-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Gly-Pro-OH | 4 | 0.23 | 38 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Gly-Pro-OH |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Phe-Ala-NH2 | 7.5 | 0.1 | 117 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Phe-Ala-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | H-Gln-Tyr-Ala-NH2 | 7.7 | 0.08 | 207 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, H-Gln-Tyr-Ala-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | L-glutamine 7-amido-4-methylcoumarin | 1.07 | 0.03 | 103 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, L-glutamine 7-amido-4-methylcoumarin |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | L-glutamine beta-naphthylamidestarting at Glu60 (Table 1 label prints F60 | 9 | 0.034 | 260 calc. | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, L-glutamine beta-naphthylamide |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | L-glutamine beta-naphthylamidestarting at Glu60 (Table 1 label prints F60; deglycosylated | 7 | 0.039 | 180 calc. | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, L-glutamine beta-naphthylamide |
| glutaminyl cyclase isoenzyme (isoQC) (human)variant I73N/C369A | Homo sapiens | L-glutamine beta-naphthylamideC-terminal His6 tag; secreted from Pichia pastoris | 3.4 | 0.035 | 229 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (human) variant I73N/C369A, L-glutamine beta-naphthylamide |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | H-Gln-Gln-OH | 8.66 | 0.092 | 95 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, H-Gln-Gln-OH |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | H-Gln-Glu-Asp-Leu-NH2 | 6.4 | 0.16 | 104 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, H-Gln-Glu-Asp-Leu-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | H-Gln-Glu-OH | 7.79 | 0.47 | 16 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, H-Gln-Glu-OH |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | H-Gln-Glu-Tyr-Phe-NH2 | 11.78 | 0.029 | 413 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, H-Gln-Glu-Tyr-Phe-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | H-Gln-Gly-OH | 4.57 | 0.16 | 28 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, H-Gln-Gly-OH |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | H-Gln-Gly-Pro-OH | 11.4 | 0.102 | 111 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, H-Gln-Gly-Pro-OH |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | H-Gln-Phe-Ala-NH2 | 24.1 | 0.06 | 403 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, H-Gln-Phe-Ala-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | H-Gln-Tyr-Ala-NH2 | 22.9 | 0.058 | 394 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, H-Gln-Tyr-Ala-NH2 |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | L-glutamine 7-amido-4-methylcoumarin | 6.98 | 0.03 | 311 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, L-glutamine 7-amido-4-methylcoumarin |
| glutaminyl cyclase isoenzyme (isoQC) (murine)variant I74N | Mus musculus | L-glutamine beta-naphthylamide | 17.48 | 0.032 | 554 | pH 8, 30 °C | Open record: glutaminyl cyclase isoenzyme (isoQC) (murine) variant I74N, L-glutamine beta-naphthylamide |