Values CatLog read from this paper

Excision of products of oxidative DNA base damage by human NTH1 protein

PMID 9890904doi:10.1021/bi9819071Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 39 records (39 values) from this paper: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 4.2.99.18

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5,6-dihydroxycytosine (lesion in oxidatively damaged DNA)Table 1	2.17 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5,6-dihydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5,6-dihydroxycytosine (lesion in oxidatively damaged DNA)Table 2	—	7.18 × 10⁻⁴	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5,6-dihydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5,6-dihydroxycytosine (lesion in oxidatively damaged DNA)Table 3	—	—	0.302	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5,6-dihydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxy-6-hydrothymine (lesion in oxidatively damaged DNA)Table 1	1.68 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxy-6-hydrothymine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxy-6-hydrothymine (lesion in oxidatively damaged DNA)Table 2	—	3.71 × 10⁻⁴	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxy-6-hydrothymine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxy-6-hydrothymine (lesion in oxidatively damaged DNA)Table 3	—	—	0.455	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxy-6-hydrothymine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)γ-irradiated under N2O (irradiation/N2O); Table 1	3.22 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)γ-irradiated under air (irradiation/air); Table 1	4.67 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)treated with H2O2/Fe(III)-EDTA (H2O2/Fe-EDTA); Table 1	3.48 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)treated with H2O2/Cu(II) (H2O2/Cu); Table 1	4.4 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)γ-irradiated under N2O (irradiation/N2O); Table 2	—	5.48 × 10⁻⁴	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)γ-irradiated under air (irradiation/air); Table 2	—	7.64 × 10⁻⁴	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)treated with H2O2/Fe(III)-EDTA (H2O2/Fe-EDTA); Table 2	—	8.61 × 10⁻⁴	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)treated with H2O2/Cu(II) (H2O2/Cu); Table 2	—	5.76 × 10⁻⁴	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)γ-irradiated under N2O (irradiation/N2O); Table 3	—	—	0.587	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)γ-irradiated under air (irradiation/air); Table 3	—	—	0.612	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)treated with H2O2/Fe(III)-EDTA (H2O2/Fe-EDTA); Table 3	—	—	0.403	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxycytosine (lesion in oxidatively damaged DNA)treated with H2O2/Cu(II) (H2O2/Cu); Table 3	—	—	0.763	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxycytosine (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxyuracil (lesion in oxidatively damaged DNA)γ-irradiated under air (irradiation/air); Table 1	1.67 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxyuracil (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxyuracil (lesion in oxidatively damaged DNA)treated with H2O2/Fe(III)-EDTA (H2O2/Fe-EDTA); Table 1	1 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxyuracil (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxyuracil (lesion in oxidatively damaged DNA)treated with H2O2/Cu(II) (H2O2/Cu); Table 1	3.18 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxyuracil (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxyuracil (lesion in oxidatively damaged DNA)γ-irradiated under air (irradiation/air); Table 2	—	6.35 × 10⁻⁴	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxyuracil (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxyuracil (lesion in oxidatively damaged DNA)treated with H2O2/Fe(III)-EDTA (H2O2/Fe-EDTA); Table 2	—	5.79 × 10⁻⁴	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxyuracil (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxyuracil (lesion in oxidatively damaged DNA)treated with H2O2/Cu(II) (H2O2/Cu); Table 2	—	0.001093	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxyuracil (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxyuracil (lesion in oxidatively damaged DNA)γ-irradiated under air (irradiation/air); Table 3	—	—	0.263	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxyuracil (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxyuracil (lesion in oxidatively damaged DNA)treated with H2O2/Fe(III)-EDTA (H2O2/Fe-EDTA); Table 3	—	—	0.173	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxyuracil (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	5-hydroxyuracil (lesion in oxidatively damaged DNA)treated with H2O2/Cu(II) (H2O2/Cu); Table 3	—	—	0.29	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), 5-hydroxyuracil (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)γ-irradiated under N2O (irradiation/N2O); Table 1	2.88 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)γ-irradiated under air (irradiation/air); Table 1	9.4 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)treated with H2O2/Fe(III)-EDTA (H2O2/Fe-EDTA); Table 1	7.52 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)treated with H2O2/Cu(II) (H2O2/Cu); Table 1	8.25 × 10⁻⁴	—	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)γ-irradiated under N2O (irradiation/N2O); Table 2	—	0.001101	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)γ-irradiated under air (irradiation/air); Table 2	—	0.003864	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)treated with H2O2/Fe(III)-EDTA (H2O2/Fe-EDTA); Table 2	—	0.003438	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)treated with H2O2/Cu(II) (H2O2/Cu); Table 2	—	0.00192	—	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)γ-irradiated under N2O (irradiation/N2O); Table 3	—	—	0.262	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)γ-irradiated under air (irradiation/air); Table 3	—	—	0.243	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)treated with H2O2/Fe(III)-EDTA (H2O2/Fe-EDTA); Table 3	—	—	0.218	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)
hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III)	Homo sapiens	thymine glycol (lesion in oxidatively damaged DNA)treated with H2O2/Cu(II) (H2O2/Cu); Table 3	—	—	0.43	pH 7.4, 37 °C	Open record: hNTH1 protein (human Nth protein, homologue of E. coli endonuclease III), thymine glycol (lesion in oxidatively damaged DNA)