Values CatLog read from this paper
Antiplasmodial activity of quinones: roles of aziridinyl substituents and the inhibition of Plasmodium falciparum glutathione reductase
PMID 19919822doi:10.1016/j.abb.2009.11.012Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 48 records (70 values) from this paper: glutathione reductase (PfGR), ferredoxin:NADP+ reductase (PfFNR), glutathione reductase (HGR), human erythrocyte from Plasmodium falciparum, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 1,4-Dihydroxy-9,10-anthraquinone | 5 | — | 800 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 1,4-Dihydroxy-9,10-anthraquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 1,4-Naphthoquinone | 25.2 | — | 3.3 × 10³ | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 1,4-Naphthoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 1,8-Dihydroxy-9,10-anthraquinone | 1.25 | — | 470 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 1,8-Dihydroxy-9,10-anthraquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 2,5-Bis(ethylamino)-3,6-diaziridinyl-1,4-benzoquinone | 1.2 | — | 27 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 2,5-Bis(ethylamino)-3,6-diaziridinyl-1,4-benzoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 2,6-Dimethyl-1,4-benzoquinone | 6.3 | — | 950 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 2,6-Dimethyl-1,4-benzoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 2-Hydroxy-1,4-naphthoquinone | 2.5 | — | 25 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 2-Hydroxy-1,4-naphthoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 2-Hydroxy-3-methyl-1,4-naphthoquinone | 2 | — | 10 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 2-Hydroxy-3-methyl-1,4-naphthoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 2-Methyl-1,4-naphthoquinone | 14.3 | — | 1 × 10³ | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 2-Methyl-1,4-naphthoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 5,8-Dihydroxy-1,4-naphthoquinone | 25 | — | 2.5 × 10³ | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 5,8-Dihydroxy-1,4-naphthoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 5-Hydroxy-1,4-naphthoquinone | 33.3 | — | 6.7 × 10³ | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 5-Hydroxy-1,4-naphthoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | 9,10-Phenanthrene quinone | 20.5 | — | 1.2 × 10³ | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), 9,10-Phenanthrene quinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | AZQ | 12.5 | — | 200 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), AZQ |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | BZQ | — | — | 20 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), BZQ |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | DZQ | 50 | — | 650 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), DZQ |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | MeDZQ | 25 | — | 2 × 10³ | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), MeDZQ |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | RH1 | 10.5 | — | 330 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), RH1 |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | Tetramethyl-1,4-benzoquinone | 12.5 | — | 250 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), Tetramethyl-1,4-benzoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | Trimethyl-1,4-benzoquinone | 20.2 | — | 460 | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), Trimethyl-1,4-benzoquinone |
| ferredoxin:NADP+ reductase (PfFNR) | Plasmodium falciparum | Trimethyl-aziridinyl-1,4-benzoquinone | 50.5 | — | 1.5 × 10³ | pH 7, 25 °C | Open record: ferredoxin:NADP+ reductase (PfFNR), Trimethyl-aziridinyl-1,4-benzoquinone |
| glutathione reductase (HGR), human erythrocyte | Homo sapiens | GSSG | 190 | — | — | pH 7, 25 °C | Open record: glutathione reductase (HGR), human erythrocyte, GSSG |
| glutathione reductase (PfGR) | Plasmodium falciparum | 1,4-Dihydroxy-9,10-anthraquinone | 0.11 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 1,4-Dihydroxy-9,10-anthraquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 1,4-Dihydroxy-9,10-anthraquinonequinone-mediated cytochrome c reduction assay | 0.1 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 1,4-Dihydroxy-9,10-anthraquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 1,4-Dihydroxy-9,10-anthraquinone | — | — | 3.2 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 1,4-Dihydroxy-9,10-anthraquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 1,4-Dihydroxy-9,10-anthraquinonequinone-mediated cytochrome c reduction assay | — | — | 3 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 1,4-Dihydroxy-9,10-anthraquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 1,4-Naphthoquinone | 1 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 1,4-Naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 1,4-Naphthoquinonequinone-mediated cytochrome c reduction assay | 1.1 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 1,4-Naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 1,4-Naphthoquinone | — | — | 5.2 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 1,4-Naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 1,4-Naphthoquinonequinone-mediated cytochrome c reduction assay | — | — | 5.7 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 1,4-Naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 1,8-Dihydroxy-9,10-anthraquinone | — | — | 0.37 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 1,8-Dihydroxy-9,10-anthraquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 2,6-Dimethyl-1,4-benzoquinone | 1.1 | — | 6.5 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 2,6-Dimethyl-1,4-benzoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 2-Methyl-1,4-naphthoquinone | 0.14 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 2-Methyl-1,4-naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 2-Methyl-1,4-naphthoquinonequinone-mediated cytochrome c reduction assay | 0.17 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 2-Methyl-1,4-naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 2-Methyl-1,4-naphthoquinone | — | — | 1.8 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 2-Methyl-1,4-naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 2-Methyl-1,4-naphthoquinonequinone-mediated cytochrome c reduction assay | — | — | 2 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 2-Methyl-1,4-naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 5,8-Dihydroxy-1,4-naphthoquinone | 7 | — | 430 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 5,8-Dihydroxy-1,4-naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 5-Hydroxy-1,4-naphthoquinone | 5.5 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 5-Hydroxy-1,4-naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 5-Hydroxy-1,4-naphthoquinonequinone-mediated cytochrome c reduction assay | 5.7 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 5-Hydroxy-1,4-naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 5-Hydroxy-1,4-naphthoquinone | — | — | 360 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 5-Hydroxy-1,4-naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 5-Hydroxy-1,4-naphthoquinonequinone-mediated cytochrome c reduction assay | — | — | 400 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 5-Hydroxy-1,4-naphthoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | 9,10-Phenanthrene quinone | 0.22 | — | 4.2 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), 9,10-Phenanthrene quinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | AZQ | — | — | 0.75 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), AZQ |
| glutathione reductase (PfGR) | Plasmodium falciparum | DZQ | 5 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), DZQ |
| glutathione reductase (PfGR) | Plasmodium falciparum | DZQquinone-mediated cytochrome c reduction assay | 5.3 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), DZQ |
| glutathione reductase (PfGR) | Plasmodium falciparum | DZQ | — | — | 40 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), DZQ |
| glutathione reductase (PfGR) | Plasmodium falciparum | DZQquinone-mediated cytochrome c reduction assay | — | — | 45 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), DZQ |
| glutathione reductase (PfGR) | Plasmodium falciparum | GSSG | 145 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), GSSG |
| glutathione reductase (PfGR) | Plasmodium falciparum | Tetramethyl-1,4-benzoquinone | 0.3 | — | 1 | pH 7, 25 °C | Open record: glutathione reductase (PfGR), Tetramethyl-1,4-benzoquinone |
| glutathione reductase (PfGR) | Plasmodium falciparum | Trimethyl-1,4-benzoquinone | 0.2 | — | — | pH 7, 25 °C | Open record: glutathione reductase (PfGR), Trimethyl-1,4-benzoquinone |