Values CatLog read from this paper
Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362
PMID 16757477doi:10.1074/jbc.m603451200Open in Browse
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CatLog read 16 records (48 values) from this paper: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) | Homo sapiens | NAD+without fumarate | 119.4 | 0.57 | 209.5 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME), NAD+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) | Homo sapiens | NAD+with 3 mM fumarate | 174.4 | 0.16 | 1.09 × 10³ | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME), NAD+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) | Homo sapiens | NADP+without fumarate | 6.71 | 1.57 | 4.27 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME), NADP+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) | Homo sapiens | NADP+with 3 mM fumarate | 13.96 | 1.19 | 11.73 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME), NADP+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362A | Homo sapiens | NAD+without fumarate | 54.08 | 0.95 | 56.93 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362A, NAD+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362A | Homo sapiens | NAD+with 3 mM fumarate | 82.15 | 0.27 | 304.3 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362A, NAD+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362A | Homo sapiens | NADP+without fumarate | 3.63 | 2.24 | 1.62 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362A, NADP+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362A | Homo sapiens | NADP+with 3 mM fumarate | 6.21 | 1.4 | 4.44 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362A, NADP+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362K | Homo sapiens | NAD+without fumarate | 27.41 | 0.9 | 30.46 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362K, NAD+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362K | Homo sapiens | NAD+with 3 mM fumarate | 55.32 | 0.55 | 100.6 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362K, NAD+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362K | Homo sapiens | NADP+without fumarate | 58.17 | 0.39 | 149.2 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362K, NADP+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362K | Homo sapiens | NADP+with 3 mM fumarate | 66.94 | 0.21 | 318.8 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362K, NADP+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362N | Homo sapiens | NAD+without fumarate | 18.24 | 1.63 | 11.19 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362N, NAD+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362N | Homo sapiens | NAD+with 3 mM fumarate | 36.44 | 0.62 | 58.77 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362N, NAD+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362N | Homo sapiens | NADP+without fumarate | 1.61 | 3.36 | 0.48 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362N, NADP+ |
| mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362N | Homo sapiens | NADP+with 3 mM fumarate | 2.66 | 2.86 | 0.93 | pH 7.4, 30 °C | Open record: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME) variant Q362N, NADP+ |