CatLogenzyme kinetics catalog

EC 1.1.1.38: malate dehydrogenase (oxaloacetate-decarboxylating)

OxidoreductasesOpen in Browse

CatLog read 122 records for EC 1.1.1.38 from 7 papers, for 3 organisms. Names in these papers: mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME), mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME), human mitochondrial NAD(P)+-dependent malic enzyme, malic enzyme and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 57 records for EC 1.1.1.38 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.38 in Browse.

Papers

PaperOrganismsRecords
Functional roles of the tetramer organization of malic enzymeHomo sapiens60
Functional roles of ATP-binding residues in the catalytic site of human mitochondrial NAD(P)+-dependent malic enzymeHomo sapiens16
Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362Homo sapiens16
Dual functional roles of ATP in the human mitochondrial malic enzymeHomo sapiens10
Structural Insights into Malic Enzyme Variants Favoring an Unnatural Redox CofactorEscherichia coli10
Structural characteristics of the nonallosteric human cytosolic malic enzymeHomo sapiens8
The Bacillus subtilis ywkA gene encodes a malic enzyme and its transcription is activated by the YufL/YufM two-component system in response to malateBacillus subtilis2

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
human mitochondrial NAD(P)+-dependent malic enzymeHomo sapiensL-malate261.419 calc.pH 7.4, 30 °CPMID 15182181Open
human mitochondrial NAD(P)+-dependent malic enzymeHomo sapiensNAD+—0.13—pH 7.4, 30 °CPMID 15182181Open
human mitochondrial NAD(P)+-dependent malic enzymevariant R197AHomo sapiensL-malate491.241 calc.pH 7.4, 30 °CPMID 15182181Open
human mitochondrial NAD(P)+-dependent malic enzymevariant R197AHomo sapiensNAD+—0.13—pH 7.4, 30 °CPMID 15182181Open
human mitochondrial NAD(P)+-dependent malic enzymevariant R197EHomo sapiensL-malate522.224 calc.pH 7.4, 30 °CPMID 15182181Open
human mitochondrial NAD(P)+-dependent malic enzymevariant R197EHomo sapiensNAD+—0.179—pH 7.4, 30 °CPMID 15182181Open
human mitochondrial NAD(P)+-dependent malic enzymevariant R542AHomo sapiensL-malate521.731 calc.pH 7.4, 30 °CPMID 15182181Open
human mitochondrial NAD(P)+-dependent malic enzymevariant R542AHomo sapiensNAD+—0.243—pH 7.4, 30 °CPMID 15182181Open
human mitochondrial NAD(P)+-dependent malic enzymevariant R542EHomo sapiensL-malate111.110 calc.pH 7.4, 30 °CPMID 15182181Open
human mitochondrial NAD(P)+-dependent malic enzymevariant R542EHomo sapiensNAD+—0.204—pH 7.4, 30 °CPMID 15182181Open
malic enzymevariant L310R/R346A/Q401CEscherichia colinicotinamide adenine dinucleotide0.020.090.22PMID 33523590Open
malic enzymevariant L310R/R346A/Q401CEscherichia colinicotinamide cytosine dinucleotide1.5350.31PMID 33523590Open
malic enzymevariant L310R/R346D/Q401CEscherichia colinicotinamide adenine dinucleotide0.020.760.03PMID 33523590Open
malic enzymevariant L310R/R346D/Q401CEscherichia colinicotinamide cytosine dinucleotide0.125.320.02PMID 33523590Open
malic enzymevariant L310R/R346F/Q401CEscherichia colinicotinamide adenine dinucleotide0.084.830.02PMID 33523590Open
malic enzymevariant L310R/R346F/Q401CEscherichia colinicotinamide cytosine dinucleotide9.3310.240.91PMID 33523590Open
malic enzymevariant L310R/R346K/Q401CEscherichia colinicotinamide adenine dinucleotide0.182.310.08PMID 33523590Open
malic enzymevariant L310R/R346K/Q401CEscherichia colinicotinamide cytosine dinucleotide3.380.447.68PMID 33523590Open
malic enzymevariant L310R/R346Y/Q401CEscherichia colinicotinamide adenine dinucleotide0.081.110.07PMID 33523590Open
malic enzymevariant L310R/R346Y/Q401CEscherichia colinicotinamide cytosine dinucleotide0.640.292.21PMID 33523590Open
malic enzyme YwkA (MaeA)Bacillus subtilisnicotinamide adenine dinucleotide (oxidized, NAD+)112—102pH 8, 37 °CPMID 12949160Open
malic enzyme YwkA (MaeA)Bacillus subtilisnicotinamide adenine dinucleotide phosphate (oxidized, NADP+)88—10pH 8, 37 °CPMID 12949160Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)Homo sapiensL-malateno fumarate238.5——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)Homo sapiensL-malate4 mM fumarate added306.4——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)Homo sapiensL-malatewithout fumarate43——pH 7.4, 30 °CPMID 24998673Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)Homo sapiensL-malatewith 5 mM fumarate55——pH 7.4, 30 °CPMID 24998673Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)Homo sapiensNAD+no fumarate—0.68—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)Homo sapiensNAD+4 mM fumarate added—0.32—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)Homo sapiensNAD+without fumarate—1.4—pH 7.4, 30 °CPMID 24998673Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)Homo sapiensNAD+with 5 mM fumarate—0.3—pH 7.4, 30 °CPMID 24998673Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant D139AHomo sapiensL-malateno fumarate114.5——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant D139AHomo sapiensL-malate4 mM fumarate added115.4——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant D139AHomo sapiensNAD+no fumarate—1.06—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant D139AHomo sapiensNAD+4 mM fumarate added—0.76—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant D568AHomo sapiensL-malateno fumarate124——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant D568AHomo sapiensL-malate4 mM fumarate added139.6——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant D568AHomo sapiensNAD+no fumarate—1.82—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant D568AHomo sapiensNAD+4 mM fumarate added—0.85—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant E90AHomo sapiensL-malateno fumarate203——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant E90AHomo sapiensL-malate4 mM fumarate added210.7——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant E90AHomo sapiensNAD+no fumarate—0.32—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant E90AHomo sapiensNAD+4 mM fumarate added—0.34—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant H142AHomo sapiensL-malateno fumarate117.9——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant H142AHomo sapiensL-malate4 mM fumarate added139.9——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant H142AHomo sapiensNAD+no fumarate—0.82—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant H142AHomo sapiensNAD+4 mM fumarate added—0.47—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant H142A/D568AHomo sapiensL-malateno fumarate112.8——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant H142A/D568AHomo sapiensL-malate4 mM fumarate added127.4——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant H142A/D568AHomo sapiensNAD+no fumarate—1.39—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant H142A/D568AHomo sapiensNAD+4 mM fumarate added—0.72—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant K57S/E59N/K73E/D102SHomo sapiensL-malatewithout fumarate5——pH 7.4, 30 °CPMID 24998673Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant K57S/E59N/K73E/D102SHomo sapiensL-malatewith 5 mM fumarate5——pH 7.4, 30 °CPMID 24998673Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant K57S/E59N/K73E/D102SHomo sapiensNAD+without fumarate—0.3—pH 7.4, 30 °CPMID 24998673Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant K57S/E59N/K73E/D102SHomo sapiensNAD+with 5 mM fumarate—0.3—pH 7.4, 30 °CPMID 24998673Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P567AHomo sapiensL-malateno fumarate141.1——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P567AHomo sapiensL-malate4 mM fumarate added164.4——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P567AHomo sapiensNAD+no fumarate—0.87—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P567AHomo sapiensNAD+4 mM fumarate added—0.51—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P573AHomo sapiensL-malateno fumarate150.2——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P573AHomo sapiensL-malate4 mM fumarate added167.1——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P573AHomo sapiensNAD+no fumarate—1.2—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P573AHomo sapiensNAD+4 mM fumarate added—0.59—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P579AHomo sapiensL-malateno fumarate234.3——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P579AHomo sapiensL-malate4 mM fumarate added284.1——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P579AHomo sapiensNAD+no fumarate—0.79—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P579AHomo sapiensNAD+4 mM fumarate added—0.39—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P580AHomo sapiensL-malateno fumarate196.5——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P580AHomo sapiensL-malate4 mM fumarate added211.6——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P580AHomo sapiensNAD+no fumarate—0.95—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant P580AHomo sapiensNAD+4 mM fumarate added—0.4—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Q51AHomo sapiensL-malateno fumarate139.1——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Q51AHomo sapiensL-malate4 mM fumarate added189.9——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Q51AHomo sapiensNAD+no fumarate—0.99—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Q51AHomo sapiensNAD+4 mM fumarate added—0.51—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Q51A/E90AHomo sapiensL-malateno fumarate140.1——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Q51A/E90AHomo sapiensL-malate4 mM fumarate added143.3——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Q51A/E90AHomo sapiensNAD+no fumarate—0.45—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Q51A/E90AHomo sapiensNAD+4 mM fumarate added—0.43—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant V581AHomo sapiensL-malateno fumarate205.8——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant V581AHomo sapiensL-malate4 mM fumarate added234.4——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant V581AHomo sapiensNAD+no fumarate—0.83—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant V581AHomo sapiensNAD+4 mM fumarate added—0.4—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant W572AHomo sapiensL-malateno fumarate150.4——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant W572AHomo sapiensL-malate4 mM fumarate added181.9——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant W572AHomo sapiensNAD+no fumarate—1.01—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant W572AHomo sapiensNAD+4 mM fumarate added—0.54—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Y570AHomo sapiensL-malateno fumarate141.9——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Y570AHomo sapiensL-malate4 mM fumarate added165.7——pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Y570AHomo sapiensNAD+no fumarate—1.07—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME)variant Y570AHomo sapiensNAD+4 mM fumarate added—0.58—pH 7.4, 30 °CPMID 19416979Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)Homo sapiensL-malateno fumarate added115.58.3913.8 calc.pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)Homo sapiensL-malate3 mM fumarate added207.93.0967.3 calc.pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)Homo sapiensNAD+without fumarate119.40.57209.5pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)Homo sapiensNAD+with 3 mM fumarate174.40.161.09 × 10³pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)Homo sapiensNADP+without fumarate6.711.574.27pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)Homo sapiensNADP+with 3 mM fumarate13.961.1911.73pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)Homo sapiensnicotinamide adenine dinucleotideno fumarate added—0.35—pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)Homo sapiensnicotinamide adenine dinucleotide3 mM fumarate added—0.23—pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant E314AHomo sapiensL-malateno fumarate added35.143.659.63 calc.pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant E314AHomo sapiensL-malate3 mM fumarate added43.922.1920.1 calc.pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant E314AHomo sapiensnicotinamide adenine dinucleotideno fumarate added—0.05—pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant E314AHomo sapiensnicotinamide adenine dinucleotide3 mM fumarate added—0.03—pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant N259AHomo sapiensL-malateno fumarate added78.137.849.97 calc.pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant N259AHomo sapiensL-malate3 mM fumarate added157.13.7442.0 calc.pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant N259AHomo sapiensnicotinamide adenine dinucleotideno fumarate added—0.42—pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant N259AHomo sapiensnicotinamide adenine dinucleotide3 mM fumarate added—0.29—pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362AHomo sapiensNAD+without fumarate54.080.9556.93pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362AHomo sapiensNAD+with 3 mM fumarate82.150.27304.3pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362AHomo sapiensNADP+without fumarate3.632.241.62pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362AHomo sapiensNADP+with 3 mM fumarate6.211.44.44pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362KHomo sapiensNAD+without fumarate27.410.930.46pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362KHomo sapiensNAD+with 3 mM fumarate55.320.55100.6pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362KHomo sapiensNADP+without fumarate58.170.39149.2pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362KHomo sapiensNADP+with 3 mM fumarate66.940.21318.8pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362NHomo sapiensNAD+without fumarate18.241.6311.19pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362NHomo sapiensNAD+with 3 mM fumarate36.440.6258.77pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362NHomo sapiensNADP+without fumarate1.613.360.48pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant Q362NHomo sapiensNADP+with 3 mM fumarate2.662.860.93pH 7.4, 30 °CPMID 16757477Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant R165AHomo sapiensL-malateno fumarate added0.0417.90.0052 calc.pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant R165AHomo sapiensL-malate3 mM fumarate added0.0437.810.0055 calc.pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant R165AHomo sapiensnicotinamide adenine dinucleotideno fumarate added—1.67—pH 7.4, 30 °CPMID 16171388Open
mitochondrial NAD(P)+-dependent malic enzyme (m-NAD-ME)variant R165AHomo sapiensnicotinamide adenine dinucleotide3 mM fumarate added—0.6—pH 7.4, 30 °CPMID 16171388Open